Department of NCC Cancer Science

18  articles.  
* There may be some overlapped articles listed due to the difference of format.

  1. Obata Y, Natsume M, Shiina I, Takahashi T, Nishida T.: Golgi retention of KIT in gastrointestinal stromal tumour cells is phospholipase D activity-dependent bioRxiv. 2025.03;

  2. Electrically Driven, Bioluminescent Compliant Devices for Soft Robotics. ACS Appl Mater Interfaces. 2025.02;

  3. Akimi Yonezawa, Kana Shimomura, Koji Okamoto & Haruna Takeda: Inhibition of BRD4 attenuated IFNγ-induced apoptosis in colorectal cancer organoids. BMC Cancer. 2025.01; ( DOI )

  1. Disruption of cotranscriptional splicing suggests that RBM39 is a therapeutic target in acute lymphoblastic leukemia. Blood. 2024.12;

  2. Mechanistic insights into lethal hyper progressive disease induced by PD-L1 inhibitor in metastatic urothelial carcinoma. NPJ Precis Oncol. 2024.09;

  3. Knockdown of CDX2 Induces microRNA-221 Up-regulation in Human Colon Cancer Cells. Anticancer Res. 2024.08;

  4. Ileuchi, H., Matsuno, Y., Kusumoto-Matsuo, R., Ueno, T., Kojima, S., Ikegami, M., Kitada, R., Okuma, H., Kojima, Y., Yonemori, K., Yatabe, Y., Takamochi, K., Suzuki, K., Yoshioka, K., Mano, H., Kohsaka, S.: GLI1 confers resistance to PARP inhibitors by activating the DNA damage repair pathway. Oncogene. 2024.08; 43 3037-3048. ( DOI )

  5. Inhibition of TOPORS ubiquitin ligase augments the efficacy of DNA hypomethylating agents through DNMT1 stabilization. Nat Commun. 2024.08;

  6. Iyoda S, Yoshida K, Shoji K, Ito N, Tanaka M, Nannya Y, Yamato G, Tsujimoto S, Shiba N, Hayashi Y, Shiozawa Y, Shiraishi Y, Chiba K, Okada A, Tanaka H, Miyano S, Koga Y, Goto H, Moritake H, Terui K, Ito E, Kiyokawa N, Tomizawa D, Taga T, Tawa A, Takita J, Nishikori M, Adachi S, Ogawa S, Matsuo H: KRAS G12 mutations as adverse prognostic factors in KMT2A-rearranged acute myeloid leukemia. Leukemia. 2024.07; 38 (7): 1609-1612. ( PubMed , DOI )

  7. Natsume M, Niwa M, Ichikawa S, Okamoto T, Tsutsui H, Usukura D, Murata T, Abe R, Shimonaka M, Nishida T, Shiina I & Obata Y: Brefeldin A and M-COPA block the export of RTKs from the endoplasmic reticulum via simultaneous inactivation of ARF1, ARF4, and ARF5 J. Biol. Chem.. 2024.06; 300 (6): 107327.

  8. Sato T, Yoshida K, Toki T, Kanezaki R, Terui K, Saiki R, Ojima M, Ochi Y, Mizuno S, Yoshihara M, Uechi T, Kenmochi N, Tanaka S, Matsubayashi J, Kisai K, Kudo K, Yuzawa K, Takahashi Y, Tanaka T, Yamamoto Y, Kobayashi A, Kamio T, Sasaki S, Shiraishi Y, Chiba K, Tanaka H, Muramatsu H, Hama A, Hasegawa D, Sato A, Koh K, Karakawa S, Kobayashi M, Hara J, Taneyama Y, Imai C, Hasegawa D, Fujita N, Yoshitomi M, Iwamoto S, Yamato G, Saida S, Kiyokawa N, Deguchi T, Ito M, Matsuo H, Adachi S, Hayashi Y, Taga T, Saito AM, Horibe K, Watanabe K, Tomizawa D, Miyano S, Takahashi S, Ogawa S, Ito E: Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms. Blood. 2024.06; 143 (25): 2627-2643. ( PubMed , DOI )

  9. Kohsaka, S., Yagishita, S., Shirai, Y., Matsuno, Y., Ueno, T., Kojima, S., Ileuchi, H., Ikegami, M., Kitada, R., Yoshioka, K., Toshimitsu, K., Tabata, K., Yokoi, A., Doi, T., Yamamoto, N., Owa, T., Hamada, A., Mano, H.: An RBM39 inhibitor, E7820, induces synthetic lethality in cancer cells with homologous recombination repair deficiency npj Precision Oncology. 2024.05; 8 117. ( DOI )

  10. Metabolic reprogramming regulated by TRAF6 contributes to the leukemia progression. Leukemia. 2024.04;

  11. Manaka, Y., Kusumoto-Matsuo, R., Matsuno, Y., Asai, H., and Yoshioka, K.: Single Base Substitution Signatures 17a, 17b, and 40 Are Induced by γ-Ray Irradiation in Association with Increased ROS Levels. Heliyon. 2024.03; 9 e28044. ( DOI )

  12. Naoko Iida, Yukari Muranaka, Jun Won Park, Shigeki Sekine, Neal G. Copeland, Nancy A. Jenkins, Yuichi Shiraishi, Masanobu Oshima, Haruna Takeda: Sleeping Beauty transposon mutagenesis in mouse intestinal organoids identifies genes involved in tumor progression and metastasis Cancer Gene Therapy . 2024.01; ( DOI )

  13. Noerenberg, D., Briest, F., Hennch, C., Yoshida, K., Hablesreiter, R., Takeuchi, Y., Ueno, H., Staiger, A. M., Ziepert, M., Asmar, F., Locher, B. N., Toth, E., Weber, T., Amini, R. M., Klapper, W., Bouzani, M., Poeschel, V., Rosenwald, A., Held, G., Campo, E., Ishaque, N., Stamatopoulos, K., Kanellis, G., Anagnostopoulos, I., Bullinger, L., Goldschmidt, N., Zinzani, P. L., Bodor, C., Rosenquist, R., Vassilakopoulos, T. P., Ott, G., Ogawa, S., Damm, F.: Genetic Characterization of Primary Mediastinal B-Cell Lymphoma: Pathogenesis and Patient Outcomes. J Clin Oncol. 2024; 42 (4): 452-466. ( PubMed , DOI )

  14. Aoki, T., Shiba, N., Tsujimoto, S., Yamato, G., Hara, Y., Kato, S., Yoshida, K., Ogawa, S., Hayashi, Y., Iwamoto, S., Taki, T., Shimada, A., Iijima-Yamashita, Y., Horibe, K., Tawa, A., Taga, T., Adachi, S., Tomizawa, D.: High IL2RA/CD25 expression is a prognostic stem cell biomarker for pediatric acute myeloid leukemia without a core-binding factor. Pediatr Blood Cancer. 2024; 71 (2): e30803. ( PubMed , DOI )

  1. Halik, A., Tilgner, M., Silva, P., Estrada, N., Altwasser, R., Jahn, E., Heuser, M., Hou, H. A., Pratcorona, M., Hills, R. K., Metzeler, K. H., Fenwarth, L., Dolnik, A., Terre, C., Kopp, K., Blau, O., Szyska, M., Christen, F., Kronke, J., Vasseur, L., Lowenberg, B., Esteve, J., Valk, P. J. M., Duchmann, M., Chou, W. C., Linch, D. C., Dohner, H., Gale, R. E., Dohner, K., Bullinger, L., Yoshida, K., Damm, F.: Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients. J Hematol Oncol. 2004; 17 (1): 70. ( PubMed , DOI )

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