Department of Neurology and Neurological Science

211  articles.  
* There may be some overlapped articles listed due to the difference of format.

  1. Kawai, H; Nishida, Y; Ishiguro, T; Akaza, M; Miyazaki, S; Yokota, T: Severe respiratory failure secondary to unilateral phrenic nerve injury: A case report NEUROLOGY AND CLINICAL NEUROSCIENCE. 2024.11; 12 (6): 379-382. ( DOI )

  2. Yokote H, Miyazaki Y, Fujimori J, Nishida Y, Toru S, Niino M, Nakashima I, Miura Y, Yokota T: Slowly expanding lesions are associated with disease activity and gray matter loss in relapse-onset multiple sclerosis. Journal of neuroimaging : official journal of the American Society of Neuroimaging. 2024.10; ( PubMed , DOI )

  3. Kuwabara S, Kusunoki S, Kuwahara M, Yamano Y, Nishida Y, Ishida H, Kasuya T, Kupperman E, Lin Q, Frick G, Misawa S: Efficacy and safety of eculizumab in Guillain-Barré syndrome: A phase 3, multicenter, double-blind, randomized, placebo-controlled clinical trial. Journal of the peripheral nervous system : JPNS. 2024.09; 29 (3): 339-349. ( PubMed , DOI )

  4. Chikada Ayaka, Orimo Kenta, Mitsui Jun, Matsukawa Takashi, Ishiura Hiroyuki, Toda Tatsushi, Mizusawa Hidehiro, Takahashi Yuji, Katsuno Masahisa, Hara Kazuhiro, Onodera Osamu, Ishihara Tomohiko, Tada Masayoshi, Kuwabara Satoshi, Sugiyama Atsuhiko, Yamanaka Yoshitaka, Takahashi Ryosuke, Sawamoto Nobukatsu, Sakato Yusuke, Ishimoto Tomoyuki, Hanajima Ritsuko, Watanabe Yasuhiro, Takigawa Hiroshi, Adachi Tadashi, Abe Koji, Yamashita Toru, Takashima Hiroshi, Higashi Keiko, Kira Junichi, Yabe Ichiro, Matsushima Masaaki, Ogata Katsuhisa, Ishikawa Kinya, Nishida Yoichiro, Ishiguro Taro, Ozaki Kokoro, Nagata Tetsuya, Tsuji Shoji: The Japan MSA registry: A multicenter cohort study of multiple system atrophy(タイトル和訳中) Neurology and Clinical Neuroscience. 2024.09; 12 (5): 271-277. ( ichushi )

  5. Takahashi S, Ono D, Shintaku H, Oyama J, Nishida Y, Ishikawa K, Yokota T: Cryptogenic New-onset Refractory Status Epilepticus with Hyperintensity of T1-weighted Magnetic Resonance Imaging in the Bilateral Basal Ganglia: An Autopsy Report. Internal medicine (Tokyo, Japan). 2024.09; ( PubMed , DOI )

  6. Yokote H, Miyazaki Y, Fujimori J, Nishida Y, Toru S, Niino M, Nakashima I, Miura Y, Yokota T: Characterization of Japanese multiple sclerosis patients with progression independent of relapse activity: A 2-year multicenter cohort study. Journal of neuroimmunology. 2024.07; 394 578407. ( PubMed , DOI )

  7. Taiki Matsubayashi, Kotaro Yoshioka, Su Su Lei Mon, Maho Katsuyama, Chunyan Jia, Takao Yamaguchi, Rintaro Iwata Hara, Tetsuya Nagata, Osamu Nakagawa, Satoshi Obika, Takanori Yokota: Favorable efficacy and reduced acute neurotoxicity by antisense oligonucleotides with 2′,4′-BNA/LNA with 9-(aminoethoxy)phenoxazine Mol Ther Nucleic Acids. 2024.03;

  8. Okamoto T, Ishizuka T, Shimizu R, Asahina Y, Nakamura H, Shimizu Y, Nishida Y, Yokota T, Lin Y, Sato W, Yamamura T: Efficacy and Safety of the Natural Killer T Cell-Stimulatory Glycolipid OCH-NCNP1 for Patients With Relapsing Multiple Sclerosis: Protocol for a Randomized Placebo-Controlled Clinical Trial. JMIR research protocols. 2024.01; 13 e46709. ( PubMed , DOI )

  1. Chunyan Jia, Su Su Lei Mon, Ying Yang, Maho Katsuyama, Kie Yoshida-Tanaka, Tetsuya Nagata, Kotaro Yoshioka, Takanori Yokota: Change of intracellular calcium level causes acute neurotoxicity by antisense oligonucleotides via CSF route Molecular Therapy Nucleic Acids. 2023.03;

  2. Takaaki Koide, Shintaro Mandai*, Reo Kitaoka, Hisazumi Matsuki, Motoko Chiga, Kouhei Yamamoto, Kotaro Yoshioka, Yohsuke Yagi, Soichiro Suzuki, Tamami Fujiki, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Soichiro Iimori, Shotaro Naito, Eisei Sohara, Tatemitsu Rai, Takanori Yokota, Shinichi Uchida: Circulating Extracellular Vesicle-Propagated microRNA Signature as a Vascular Calcification Factor in Chronic Kidney Disease. Circ Res. 2023.01; ( PubMed , DOI )

  1. Taiki Matsubayashi, Nobuo Sanjo: Systematic Review of Clinical and Pathophysiological Features of Genetic Creutzfeldt–Jakob Disease Caused by a Val-to-Ile Mutation at Codon 180 in the Prion Protein Gene International Journal of Molecular Science. 2022.12; 23 15172.

  2. Masaaki Niino, Shoko Fukumoto, Tatsusada Okuno, Nobuo Sanjo, Hikoaki Fukaura, Masahiro Mori, Takashi Ohashi, Hideyuki Takeuchi, Yuko Shimizu, Juichi Fujimori, Izumi Kawachi, Jun-ichi Kira, Eri Takahashi, Yusei Miyazaki, Nobuhiro Mifune: Health related quality of life in Japanese patients with multiple sclerosis Journal of Neurology. 2022.11; 270 1011-1018.

  3. Yokote H, Miyazaki Y, Toru S, Nishida Y, Hattori T, Niino M, Sanjo N, Yokota T: High-efficacy therapy reduces subcortical grey matter volume loss in Japanese patients with relapse-onset multiple sclerosis: A 2-year cohort study. Mult Scler Relat Disord. 2022.07; 67 104077. ( PubMed , DOI )

  4. Tamaki Kana, Nishida Yoichiro, Sanjo Nobuo, Yokota Takanori: A patient with generalized myasthenia gravis facing an impending crisis triggered by early fast-acting treatment Clinical and Experimental Neuroimmunology. 2022.05; 13 (2): 99-101. ( ichushi )

  5. Koki Kosami, Ryusuke Ae, Tsuyoshi Hamaguchi, Nobuo Sanjo, Tadashi Tsukamoto, Tetsuyuki Kitamoto, Masahito Yamada, Hidehiro Mizusawa, Yosikazu Nakamura: Methionine homozygosity for PRNP polymorphism and susceptibility to human prion diseases Journal of Neurology, Neurosurgery, and Psychiatry. 2022.04; 93 779-784.

  6. Yamada Akane, Nishida Yoichiro, Wake Kenjiro, Nakamura Ayako, Sakamaki Yuriko, Kuwahara Hiroya, Uchihara Toshiki, Yokota Takanori: Serial ultrathin sections to identify ultrastructural localization of GLUT1 molecules in vesicles in brain endothelial cells-correlative light and electron microscopy in depth(和訳中) Microscopy. 2022.04; 71 (2): 124-131. ( ichushi )

  7. Kawano Y, Obana M, Nagata M, Mano Y, Katsuyama M, Yamamoto Y, Maeda-Minami A, Negishi K, Takagi M, Shimada S, Aoyama T: The antiplatelet effect of mirtazapine is mediated by co-blocking 5-HT#D2A#DR and α#D2#DR-adrenergic receptors on platelets: An in vitro human plasma-based study. European journal of pharmacology. 2022.02; 917 174640. ( PubMed , DOI )

  8. Yamada A, Nishida Y, Wake K, Nakamura A, Sakamaki Y, Kuwahara H, Uchihara T, Yokota T: Serial ultrathin sections to identify ultrastructural localization of GLUT1 molecules in vesicles in brain endothelial cells-correlative light and electron microscopy in depth. Microscopy (Oxford, England). 2022.02; 71 (2): 124-131. ( PubMed , DOI )

  9. Masaaki Niino, Shoko Fukumoto, Tatsusada Okuno, Nobuo Sanjo, Hikoaki Fukaura, Masahiro Mori, Takashi Ohashi, Hideyuki Takeuchi, Yuko Shimizu, Juichi Fujimori, Izumi Kawachi, Jun-ichi Kira, Eri Takahashi, Yusei Miyazaki, Nobuhiro Mifune: Correlation of the Symbol Digit Modalities Test with the Quality of Life and Depression in Japanese Patients with Multiple Sclerosis Multiple Sclerosis and Related Disorders. 2022.01; 57 103427.

  10. Yohsuke Yagi, Yutaro Asami, Mitsuki Kyoya, Takanori Yokota: Cerebral venous sinus thrombosis after mRNA-based COVID-19 vaccination. Neurol Sci. 2022.01; 43 (1): 41-43. ( PubMed , DOI )

  1. Kotaro Noda, Yohsuke Yagi, Takanori Yokota: Evaluation of the risk factors predicting thrombotic complications associated with intravenous immunoglobulin therapy in neuroimmunological diseases. Neurol Sci. 2021.12; 42 (12): 5321-5326. ( PubMed , DOI )

  2. Yoichiro Nishida,Taro Ishiguro, Takanori Yokota: Tap-Elicited Clonus of the Biceps and Triceps Brachii. JAMA Neurol. 2021.11; 79 (2): 194. ( PubMed , DOI )

  3. Shinya Akiko, Takahashi Makoto, Sato Nozomu, Nishida Yoichiro, Inaba Akira, Inaji Motoki, Yokota Takanori, Orimo Satoshi: Oculo-dento-digital Dysplasia Presenting as Spastic Paraparesis Which Was Successfully Treated by Intrathecal Baclofen Therapy Internal Medicine. 2021.07; 60 (14): 2301-2305. ( ichushi )

  4. Yoichiro Nishida, Takanori Yokota: Reversible reduction of dopamine transporter uptake in a case of hydrocephalus. Ann Neurol. 2021.05; ( PubMed , DOI )

  5. Hiroaki Yokote, Shuta Toru, Yoichiro Nishida, Takaaki Hattori, Nobuo Sanjo, Takanori Yokota : Serum amyloid A level correlates with T2 lesion volume and cortical volume in patients with multiple sclerosis. J Neuroimmunol. 2021.02; 351 577466. ( PubMed , DOI )

  6. Asami Yutaro, Nagata Tetsuya, Yoshioka Kotaro, Kunieda Taiki, Yoshida-Tanaka Kie, Bennett C. Frank, Seth Punit P., Yokota Takanori: Efficient Gene Suppression by DNA/DNA Double-Stranded Oligonucleotide In Vivo. Mol Ther. 2021.02; 29 (2): 838-847. ( PubMed , DOI )

  7. Akiko Shinya, Makoto Takahashi, Nozomu Sato, Yoichiro Nishida, Akira Inaba, Motoki Inaji, Takanori Yokota, Satoshi Orimo: A case of oculo-dento-digital dysplasia presenting as spastic paraparesis which was successfully treated by intrathecal baclofen therapy. Intern Med. 2021.02; 60 (14): 2301-2305. ( PubMed , DOI )

  8. Kawano Y, Katsuyama M, Nagata M, Obana M, Nakamatsu S, Mori A, Sakamoto N, Mano Y, Negishi K, Shimada S, Aoyama T: Antiplatelet Effect of Mirtazapine via Co-blocking of the 5-HT#D2A#DR and α#D2#DR-Adrenergic Receptors on Platelets. Biological & pharmaceutical bulletin. 2021.02; 44 (2): 238-244. ( PubMed , DOI )

  9. Mitsuru Watanabe, Yuri Nakamura, Shinya Sato, Masaaki Niino, Hikoaki Fukaura, Masami Tanaka, Hirofumi Ochi, Takashi Kanda, Yukio Takeshita, Takanori Yokota, Yoichiro Nishida, Makoto Matsui, Shigemi Nagayama, Susumu Kusunoki, Katsuichi Miyamoto, Masanori Mizuno, Izumi Kawachi, Etsuji Saji, Takashi Ohashi, Shun Shimohama, Shin Hisahara, Kazutoshi Nishiyama, Takahiro Iizuka, Yuji Nakatsuji, Tatsusada Okuno, Kazuhide Ochi, Akio Suzumura, Ken Yamamoto, Yuji Kawano, Shoji Tsuji, Makoto Hirata, Ryuichi Sakate, Tomonori Kimura, Yuko Shimizu, Akiko Nagaishi, Kazumasa Okada, Fumie Hayashi, Ayako Sakoda, Katsuhisa Masaki, Koji Shinoda, Noriko Isobe, Takuya Matsushita, Jun-Ichi Kira : HLA genotype-clinical phenotype correlations in multiple sclerosis and neuromyelitis optica spectrum disorders based on Japan MS/NMOSD Biobank data. Sci rep. 2021.01; 11 (1): 607. ( PubMed , DOI )

  1. Yoshioka Kotaro, Kunieda Taiki, Asami Yutaro, Tanaka Kie, Piao Wenying, Kuwahara Hiroya, Nishina Kazutaka, Nagata Tetsuya, Yokota Takanori: オーバーハングしたヘテロ二重鎖オリゴヌクレオチドを用いたFAPのトランスフェリンを介した送達による治療(Treatment for FAP with overhanging heteroduplex oligonucleotides by transferrin-mediated delivery) 臨床神経学. 2020.11; 60 (Suppl.): S315. ( ichushi )

  2. Asami Yutaro, Nagata Tetsuya, Yoshioka Kotaro, Kunieda Taiki, Yoshida-Tanaka Kie, Yokota Takanori: in vivoにおけるDNA/DNA二重鎖オリゴヌクレオチドによる効率的な遺伝子抑制(Efficient gene suppression by DNA/DNA double-stranded oligonucleotide in vivo) 臨床神経学. 2020.11; 60 (Suppl.): S498. ( ichushi )

  3. Sugita Y, Nishida Y, Ishibashi S, Yokota T: Convexity Subarachnoid Hemorrhage Soon after Starting a Direct Oral Anticoagulant in 2 Patients with Acute Infarction. J Stroke Cerebrovasc Dis .. 2020.11; 29 (11): 105216. ( PubMed , DOI )

  4. Nishida Y, Takahashi YK, Kanai T, Nose Y, Ishibashi S, Sanjo N, Uzawa A, Oda F, Ozawa Y, Kuwabara S, Noguchi E, Suzuki S, Nakahara J, Suzuki N, Ogawa T, Yokoyama K, Hattori N, Konno S, Fujioka T, Kawaguchi N, Hatanaka Y, Sonoo M, Kaneko J, Ogino M, Nishiyama K, Nomura K, Yokota T: Safety of tapering tacrolimus dose in patients with well-controlled anti-acetylcholine receptor antibody-positive myasthenia gravis. European journal of neurology. 2020.01; 27 (1): 100-104. ( PubMed , DOI )

  5. Lei Mon SS, Yoshioka K, Jia C, Kunieda T, Asami Y, Yoshida-Tanaka K, Piao W, Kuwahara H, Nishina K, Nagata T, Yokota T: Highly efficient gene silencing in mouse brain by overhanging-duplex oligonucleotides via intraventricular route. FEBS letters. 2020.01; 594 (9): 1413-1423. ( PubMed , DOI )

  6. Tsuyoshi Hamaguchi, Nobuo Sanjo, Ryusuke Ae, Yosikazu Nakamura, Kenji Sakai, Masaki Takao, Shigeo Murayama, Yasushi Iwasaki, Katsuya Satoh, Hiroyuki Murai, Masafumi Harada, Tadashi Tsukamoto, Hidehiro Mizusawa, Masahito Yamada.: MM2 type sporadic Creutzfeldt-Jakob disease: new diagnostic criteria for MM2-cortical type. Journal of Neurology, Neurosurgery & Psychiatry . 2020; in press in press.

  7. Kenji Sakai, Tsuyoshi Hamaguchi, Nobuo Sanjo, Hiroyuki Murai, Yasushi Iwasaki, Tadanori Hamano, Mari Honma, Moeko Noguchi-Shinohara, Ichiro Nozaki, Yosikazu Nakamura, Tetsuyuki Kitamoto, Masafumi Harada, Hidehiro Mizusawa, MasahitoYamada. : Diffusion-weighted magnetic resonance imaging in dura mater graftassociated Creutzfeldt-Jakob disease. Journal of the Neurological Sciences . 2020; in press

  1. Yanagidaira M, Nishida Y, Yokota T: Temporal correlation between serum CH50 level and symptom severity of myasthenia gravis during eculizumab therapy. Clinical neurology and neurosurgery. 2019.12; 189 105630. ( PubMed , DOI )

  2. Yoshioka Kotaro, Su Su Lei Mon , Jia Chunyan, Yamada Hiroki, Asami Yutaro, Tanaka Kie, Wenying Piao, Kuwahara Hiroya, Nishina Kazutaka, Nagata Tetsuya, Yokota Takanori: CNSを標的としたオーバーハングヘテロ二2本鎖核酸を用いた新しいアンチセンスオリゴヌクレオチド治療(A novel antisense oligonucleotide therapy by overhanging heteroduplex oligonucleotide targeting CNS) 臨床神経学. 2019.11; 59 (Suppl.): S408. ( ichushi )

  3. Masaki Ohyagi, Takashi Irioka, Takuya Ohkubo, Satoru Ishibashi, Yuko K Takahashi, Eiichiro Amano, Akira Machida, Hiroya Kuwahara, Takanori Yokota: Intrathecal IgG Synthesis and Persistent Inflammation Are Associated with White Matter Lesions in HIV-negative Patients with Cryptococcal Meningoencephalitis. Intern. Med.. 2019.11; 58 (21): 3077-3082. ( PubMed , DOI )

  4. Yokote Hiroaki, Amano Ryota, Toru Shuta, Hattori Takaaki, Nishida Yoichiro, Sanjo Nobuo, Yokota Takanori: 多発性硬化症患者における血清アミロイドA蛋白の上昇と脳萎縮との関連(Brain atrophy is associated with higher serum amyloid A levels in patients with multiple sclerosis) 臨床神経学. 2019.11; 59 (Suppl.): S400. ( ichushi )

  5. Amano Akiko, Sanjo Nobuo, Nakakido Makoto, Tsumoto Kouhei, Matsubara Etsuro, Furukawa Fumiko, Nishida Yoichiro, Saito Takashi, Saido Takaomi, Yokota Takanori: ドットブロット法を用いたマウス脳におけるAβオリゴマーの定量的評価(Quantitative evaluation of Aβ oligomer in mouse brain using dot blot method) Dementia Japan. 2019.10; 33 (4): 515. ( ichushi )

  6. Murai H., Nakamura Y., Matsushita T., Kitamoto T., Tsuboi Y., Sanjo N., Yamada M., Mizusawa H.: Epidemiological study of Gerstmann-Straussler-Scheinker disease with codon 102 mutation in Japan JOURNAL OF THE NEUROLOGICAL SCIENCES. 2019.10; 405 (73): 73 -73. ( DOI )

  7. Ohara M, Sanjo N, Hattori T, Oyama J, Hamada M, Ozaki K, Yokota T: Olivary hypertrophy improved by steroid treatment: Two case reports with unique presentations. Journal of neuroimmunology. 2019.09; 334 577003. ( PubMed , DOI )

  8. Yoshioka K, Kunieda T, Asami Y, Guo H, Miyata H, Yoshida-Tanaka K, Sujino Y, Piao W, Kuwahara H, Nishina K, Hara RI, Nagata T, Wada T, Obika S, Yokota T: Highly efficient silencing of microRNA by heteroduplex oligonucleotides. Nucleic acids research. 2019.08; 47 (14): 7321-7332. ( PubMed , DOI )

  9. Minikel Eric Vallabh, Vallabh Sonia M., Orseth Margaret C., Brandel Jean-Philippe, Haik Stephane, Laplanche Jean-Louis, Zerr Inga, Parchi Piero, Capellari Sabina, Safar Jiri, Kenny Janna, Fong Jamie C., Takada Leonel T., Ponto Claudia, Hermann Peter, Knipper Tobias, Stehmann Christiane, Kitamoto Tetsuyuki, Ae Ryusuke, Hamaguchi Tsuyoshi, Sanjo Nobuo, Tsukamoto Tadashi, Mizusawa Hidehiro, Collins Steven J., Chiesa Roberto, Roiter Ignazio, de Pedro-Cuesta Jesus, Calero Miguel, Geschwind Michael D., Yamada Masahito, Nakamura Yosikazu, Mead Simon: Age at onset in genetic prion disease and the design of preventive clinical trials NEUROLOGY. 2019.07; 93 (2): E125-E134. ( PubMed , DOI )

  10. Guo L, Bertola DR, Takanohashi A, Saito A, Segawa Y, Yokota T, Ishibashi S, Nishida Y, Yamamoto GL, Franco JFDS, Honjo RS, Kim CA, Musso CM, Timmons M, Pizzino A, Taft RJ, Lajoie B, Knight MA, Fischbeck KH, Singleton AB, Ferreira CR, Wang Z, Yan L, Garbern JY, Simsek-Kiper PO, Ohashi H, Robey PG, Boyde A, Matsumoto N, Miyake N, Spranger J, Schiffmann R, Vanderver A, Nishimura G, Passos-Bueno MRDS, Simons C, Ishikawa K, Ikegawa S: Bi-allelic CSF1R Mutations Cause Skeletal Dysplasia of Dysosteosclerosis-Pyle Disease Spectrum and Degenerative Encephalopathy with Brain Malformation. American journal of human genetics. 2019.05; 104 (5): 925-935. ( PubMed , DOI )

  11. Nishida Yoichiro, Hizume Masaki, Fumimura Yuichi, Ichikawa Tadashi: ドネペジルにより改善した小脳性認知情動症候群(Cerebellar Cognitive Affective Syndrome Improved by Donepezil) Internal Medicine. 2019.04; 58 (7): 1003-1006. ( ichushi )

  12. Furukawa F, Ishikawa K, Yokota T, Sanjo N: Cross-Sectional Area Analysis of the Head of the Caudate Nucleus in Huntington's Disease. European neurology. 2019.04; 81 (1-2): 13-18. ( PubMed , DOI )

  13. Hashimoto S, Inaji M, Nariai T, Kobayashi D, Sanjo N, Yokota T, Ishii K, Taketoshi M: Usefulness of [11C] Methionine PET in the Differentiation of Tumefactive Multiple Sclerosis from High Grade Astrocytoma. Neurologia medico-chirurgica. 2019.04; 59 (5): 176-183. ( PubMed , DOI )

  14. Takahashi Yuko K., Nishida Yoichiro, Nose Yurie, Ishibashi Satoru, Sanjo Nobuo, Kanai Tetsuya, Uzawa Akiyuki, Oda Fumiko, Ozawa Yukiko, Kuwabara Satoshi, Yokota Takanori: Calcineurin Inhibitors Can Be Safely Reduced in Most Patients with Well-controlled Myasthenia Gravis NEUROLOGY. 2019.04; 92 (15):

  15. Takahashi Yuko K., Nishida Yoichiro, Nose Yurie, Ishibashi Satoru, Sanjo Nobuo, Kanai Tetsuya, Uzawa Akiyuki, Oda Fumiko, Ozawa Yukiko, Kuwabara Satoshi, Yokota Takanori: Calcineurin Inhibitors Can Be Safely Reduced in Most Patients with Well-controlled Myasthenia Gravis NEUROLOGY. 2019.04; 92 (15):

  16. Yokote H., Amano R., Toru S., Hattori T., Nishida Y., Sanjo N., Yokota T.: Brain Atrophy is Associated with Higher Serum Amyloid A Levels in Patients with Relapsing and Remitting Multiple Sclerosis and Clinically Isolated Syndrome MULTIPLE SCLEROSIS JOURNAL. 2019.03; 25 (3): 442.

  17. Yokote H., Amano R., Toru S., Hattori T., Nishida Y., Sanjo N., Yokota T.: Brain Atrophy is Associated with Higher Serum Amyloid A Levels in Patients with Relapsing and Remitting Multiple Sclerosis and Clinically Isolated Syndrome MULTIPLE SCLEROSIS JOURNAL. 2019.03; 25 (3): 442.

  18. Sanjo N, Nose Y, Shishido-Hara Y, Mizutani S, Sekijima Y, Aizawa H, Tanizawa T, Yokota T: A controlled inflammation and a regulatory immune system are associated with more favorable prognosis of progressive multifocal leukoencephalopathy. Journal of neurology. 2019.02; 266 (2): 369-377. ( PubMed , DOI )

  19. Takahashi K, Yanai S, Takisawa S, Kono N, Arai H, Nishida Y, Yokota T, Endo S, Ishigami A: Vitamin C and vitamin E double-deficiency increased neuroinflammation and impaired conditioned fear memory. Archives of biochemistry and biophysics. 2019.01; 663 120-128. ( PubMed , DOI )

  20. Amano E, Ozaki K, Ishibashi S, Sanjo N, Yokota T: Remarkable improvement in progressive multifocal leukoencephalopathy following acute pyelonephritis with bacteremia. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 2019.01; 62 226-228. ( PubMed , DOI )

  21. Y. Nishida, Y. K. Takahashi, T. Kanai, Y. Nose, S. Ishibashi, N. Sanjo, A. Uzawa, F. Oda, Y. Ozawa, S. Kuwabara, E. Noguchi, S. Suzuki, J. Nakahara, N. Suzuki, T. Ogawa, K. Yokoyama, N. Hattori, S. Konno, T. Fujioka, N. Kawaguchi, Y. Hatanaka, M. Sonoo, J. Kaneko, M. Ogino, K. Nishiyama, K. Nomura, T. Yokota. : Safety of tapering tacrolimus dose in patients with well-controlled anti-acetylcholine receptor antibody-positive myasthenia gravis. European Journal of Neurology . 2019; 27 (1): 100-104.

  22. Eric Vallabh Minikel, Sonia M Vallabh, Margaret C Orseth, Jean-Philippe Brandel, Stéphane Haïk, Jean-Louis Laplanche, Inga Zerr, Piero Parchi, Sabina Capellari, Jiri Safar, Janna Kenny, Jamie C Fong, Leonel T Takada, Claudia Ponto, Peter Hermann, Tobias Knipper, Christiane Stehmann, Tetsuyuki Kitamoto, Ryusuke Ae, Tsuyoshi Hamaguchi, Nobuo Sanjo, Tadashi Tsukamoto, Hidehiro Mizusawa, Steven J Collins, Roberto Chiesa, Ignazio Roiter, Jesús de Pedro-Cuesta, Miguel Calero, Michael D Geschwind, Masahito Yamada, Yosikazu Nakamura, Simon Mead. : Age at onset in genetic prion disease and the design of preventive clinical trials. Neurology. 2019; 93 125-134.

  23. Eiichiro Amano, Kokoro Ozaki, Satoru Ishibashi, Nobuo Sanjo, Takanori Yokota. : Remarkable improvement in progressive multifocal leukoencephalopathy following acute pyelonephritis with bacteremia. Journal of Clinical Neuroscience . 2019; 62 226-228.

  1. Yoshioka Kotaro, Kunieda Taiki, Asami Yutaro, Guo Huija, Enomoto Seiya, Miyata Haruka, Tanaka Kie, Piao Wenying, Kuwahara Hiroya, Nishina Kazutaka, Nagata Tetsuya, Yokota Takanori: 新しい種類の二本鎖オリゴヌクレオチドはin vivoにおいてmicroRNAサイレンシングの効力を増強する(A new class of double-stranded oligonucleotide enhances in vivo potency of microRNA silencing) 臨床神経学. 2018.12; 58 (Suppl.): S234. ( ichushi )

  2. Mon Su Su Lei, Yoshioka Kotaro, Kunieda Taiki, Asami Yutaro, Tanaka Kie, Piao Wenying, Kuwahara Hiroya, Nishina Kazutaka, Nagata Tetsuya, Yokota Takanori: アンチセンスオリゴヌクレオチド二本鎖の新しい構造は脳室内経路を介した効果を改善する(A novel structure of duplex antisense oligonucleotides improves potency via intraventricular route) 臨床神経学. 2018.12; 58 (Suppl.): S394. ( ichushi )

  3. Nishida Y, Hizume M, Fumimura Y, Ichikawa T: Cerebellar Cognitive Affective Syndrome Improved by Donepezil. Internal medicine (Tokyo, Japan). 2018.12; ( PubMed , DOI )

  4. Miura M, Numasawa Y, Takahisa M, Ozaki K, Irioka T, Nishida Y, Ishibashi S, Yokota T: Levodopa-responsive truncal tremor in a patient with spinocerebellar ataxia type 3. Journal of the neurological sciences. 2018.09; 392 32-33. ( PubMed , DOI )

  5. Ozaki K, Ohkubo T, Yamada T, Yoshioka K, Ichijo M, Majima T, Kudo S, Akashi T, Honda K, Ito E, Watanabe M, Sekine M, Hamagaki M, Eishi Y, Sanjo N, Ishibashi S, Mizusawa H, Yokota T: Progressive Encephalomyelitis with Rigidity and Myoclonus Resolving after Thymectomy with Subsequent Anasarca: An Autopsy Case. Internal medicine (Tokyo, Japan). 2018.07; ( PubMed , DOI )

  6. Misawa S, Kuwabara S, Sato Y, Yamaguchi N, Nagashima K, Katayama K, Sekiguchi Y, Iwai Y, Amino H, Suichi T, Yokota T, Nishida Y, Kanouchi T, Kohara N, Kawamoto M, Ishii J, Kuwahara M, Suzuki H, Hirata K, Kokubun N, Masuda R, Kaneko J, Yabe I, Sasaki H, Kaida KI, Takazaki H, Suzuki N, Suzuki S, Nodera H, Matsui N, Tsuji S, Koike H, Yamasaki R, Kusunoki S, Japanese Eculizumab Trial for GBS (JET-GBS) Study Group.: Safety and efficacy of eculizumab in Guillain-Barré syndrome: a multicentre, double-blind, randomised phase 2 trial. The Lancet. Neurology. 2018.06; 17 (6): 519-529. ( PubMed , DOI )

  7. Guo Huijia, Yoshioka Kotaro, Kunieda Taiki, Asami Yutaro, Miyata Haruka, Yoshida-Tanaka Kie, Nagata Tetsuya, Yokota Takanori: Efficacy of microRNA silencing by lipid-conjugated double-stranded antisense oligonucleotides Journal of Medical and Dental Sciences. 2018.06; 65 (2): 83-88. ( ichushi )

  8. Hiroya Kuwahara, Jindong Song, Takahiro Shimoura, Kie Yoshida-Tanaka, Tadahaya Mizuno, Tatsuki Mochizuki, Satoshi Zeniya, Fuying Li, Kazutaka Nishina, Tetsuya Nagata, Shingo Ito, Hiroyuki Kusuhara, Takanori Yokota: Modulation of blood-brain barrier function by a heteroduplex oligonucleotide in vivo. Sci Rep. 2018.03; 8 (1): 4377. ( PubMed , DOI )

  9. Yoko Ito, Nobuo Sanjo, Masaki Hizume, Atsushi Kobayashi, Tetsuya Ohgami, Katsuya Satoh, Tsuyoshi Hamaguchi Masahito Yamada, Tetsuyuki Kitamoto, Hidehiro Mizusawa, Takanori Yokota: Biochemical features of genetic Creutzfeldt-Jakob disease with valine-to-isoleucine substitution at codon 180 on the prion protein gene. Biochemical and Biophysical Research Communications. 2018.02; 496 (4): 1055-1061. ( PubMed , DOI )

  10. Furukawa F, Sanjo N, Kobayashi A, Hamaguchi T, Yamada M, Kitamoto T, Mizusawa H, Yokota T: Specific amyloid-β42 deposition in the brain of a Gerstmann-Sträussler-Scheinker disease patient with a P105L mutation on the prion protein gene. Prion. 2018; 12 (5-6): 315-319. ( PubMed , DOI )

  11. Ohara Masahiro, Ozaki Kokoro, Ohkubo Takuya, Yamada Akane, Numasawa Yoshiyuki, Tanaka Keisuke, Tomii Shohei, Ishibashi Satoru, Sanjo Nobuo, Yokota Takanori: Myasthenia Gravis Complicated with Peripheral T-cell Lymphoma, Not Otherwise Specified (PTCL-NOS), Following Thymectomy and Longstanding Tacrolimus Therapy INTERNAL MEDICINE. 2018; 57 (4): 601-604. ( PubMed , DOI )

  1. Masaaki Niino,Toshiyuki Fukazawa,Jun-ichi Kira,Tatsusada Okuno,Masahiro Mori,Nobuo Sanjo,Takashi Ohashi,Hiroaki Fukaura,Juichi Fujimori,Yuko Shimizu,Nobuhiro Mifune,Yusei Miyazaki,Eri Takahashi,Seiji Kikuchi,Dawn Langdon,Ralph HB Benedict,Makoto Matsui: Validation of the Brief International Cognitive Assessment for Multiple Sclerosis in Japan. Multiple Sclerosis Journal. 2017.12; 26 (3): ( PubMed , DOI )

  2. Shuta Toru, Tadashi Kanouchi, Takanori Yokota, Yosuke Yagi, Akira Machida, Takayoshi Kobayashi: Utility of Autonomic Function Tests to Differentiate Dementia with Lewy Bodies and Parkinson Disease with Dementia from Alzheimer Disease. Eur. Neurol.. 2017.11; 79 (1-2): 27-32. ( PubMed , DOI )

  3. Yoshioka K., Kunieda T., Asami Y., Sujino Y., Tanaka K., Piao W., Kuwahara H., Nishina K., Nagata T., Yokota T.: Dual overhanging-duplex oligonucleotide improved efficacy and safety in gene therapy for FAP JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 140. ( DOI )

  4. Y Anraku, H Kuwahara, Y Fukusato, A Mizoguchi, T Ishii, K Nitta, Y Matsumoto, K Toh, K Miyata, S Uchida, K Nishina, K Osada, K Itaka, N Nishiyama, H Mizusawa, T Yamasoba, T Yokota, K Kataoka: Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain. Nat Commun. 2017.10; 8 (1): 1001. ( PubMed , DOI )

  5. Nishida Y., Winkler E., Sagare A., De Vivo D., Zlokovic B.: Decreased glucose transporter 1 expression at the blood-brain barrier exacerbates Alzheimer disease-like phenotypes in mouse models JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 768. ( DOI )

  6. Yamada A., Numasawa Y., Hattori T., Ozaki K., Ishibashi S., Nishida Y., Kanouchi T., Sanjo N., Takanori Y.: Signal changes of skeletal muscle MRI in peripheral nerve disorders JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 1068. ( DOI )

  7. Ichinose K., Ishibashi S., Miyashita A., Sanjo N., Uchida K., Suzuki Y., Sekine M., Kobayashi D., Eishi Y., Yokota T.: Clinicopathological features of neuromuscular sarcoidosis and its immunoreactivity profiles of P. acne JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 465. ( DOI )

  8. Numasawa Y., Hattori T., Ishiai S., Kobayashi Z., Kamata T., Kotera M., Ishibashi S., Sanjo N., Mizusawa H., Yokota T.: Components of depressive disorder due to raphe-nuclei damage: Subclass analysis of patients with brainstem infarction JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 636. ( DOI )

  9. Hamaguchi T., Sakai K., Kobayashi A., Kitamoto T., Ae R., Nakamura Y., Sanjo N., Arai K., Koide M., Katada F., Tsukamoto T., Mizusawa H., Yamada M.: Investigation of clinical and pathological features of "sporadic Creutzfeldt-Jakob disease" with history of neurosurgery to identify iatrogenic cases JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 416-417. ( DOI )

  10. Nozomu Sato, Nozomi Toide, Mami Kizawa, Takuya Ohkubo, Satoru Ishibashi, Nobuo Sanjo, Takanori Yokota: Methotrexate-associated lymphoproliferative disorder in a patient with neuromyelitis optica spectrum disorder: An implication for pathogenesis mediated by Epstein-Barr virus. J. Neurol. Sci.. 2017.08; 379 219-221. ( PubMed , DOI )

  11. Hiroaki Yokote,Tomoyuki Kamata,Nobuo Sanjo,Takanori Yokota: Serum retinol levels are associated with brain volume loss in patients with multiple sclerosis. Multiple Sclerosis Journal 2017. 2017.07; 3 (3): ( DOI )

  12. Maya Higuma,Nobuo Sanjo,Hiroshi Mitoma,Mitsuru Yoneyama,Takanori Yokota: Whole-day gait monitoring in patients with Alzheimer's disease: a relationship between attention and gait cycle. Journal of Alzheimer's Disease Reports 2017 . 2017.07; 1 (1): 1-8. ( DOI )

  13. Yoshiyuki Numasawa, Takaaki Hattori, Sumio Ishiai, Zen Kobayashi, Tomoyuki Kamata, Minoru Kotera, Satoru Ishibashi, Nobuo Sanjo, Hidehiro Mizusawa, Takanori Yokota.: Depressive disorder is associated with brainstem infarction involving raphe nuclei. Journal of Affective Disorders. 2017.04; (213): 191-198.

  14. Yoshiyuki Numasawa, Takaaki Hattori, Sumio Ishiai, Zen Kobayashi, Tomoyuki Kamata, Minoru Kotera, Satoru Ishibashi, Nobuo Sanjo, Hidehiro Mizusawa, Takanori Yokota: Depressive disorder may be associated with raphe nuclei lesions in patients with brainstem infarction. Journal of Affective Disorder. 2017.04; 213 191-198. ( PubMed , DOI )

  15. Yohsuke Yagi, Takuya Ohkubo, Hideya Kawaji, Akira Machida, Haruka Miyata, Saori Goda, Sugata Roy, Yoshihide Hayashizaki, Harukazu Suzuki, Takanori Yokota: Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. Neurosci. Lett.. 2017.01; 636 48-57. ( PubMed , DOI )

  16. Maya Higuma, Nobuo Sanjo, Hiroshi Mitoma, Mitsuru Yoneyama, Takanori Yokota. : Whole-day gait monitoring in patients with Alzheimer disease: a relationship between attention and gait cycle. Journal of Alzheimer’s Disease Reports. 2017; 1 (1): 1-8.

  1. Nobuko Yamaguchi, Sonoko Misawa, Yasunori Sato, Kengo Nagashima, Kanako Katayama, Yukari Sekiguchi, Yuta Iwai, Hiroshi Amino, Tomoki Suichi, Takanori Yokota, Yoichiro Nishida, Nobuo Kohara, Koichi Hirata, Kazutoshi Nishiyama, Ichiro Yabe, Ken-Ichi Kaida, Norihiro Suzuki, Hiroyuki Nodera, Shoji Tsuji, Haruki Koike, Jun-Ichi Kira, Hideki Hanaoka, Susumu Kusunoki, Satoshi Kuwabara, : A Prospective, Multicenter, Randomized Phase II Study to Evaluate the Efficacy and Safety of Eculizumab in Patients with Guillain-Barré Syndrome (GBS): Protocol of Japanese Eculizumab Trial for GBS (JET-GBS). JMIR Res Protoc. 2016.11; 5 (4): e210. ( PubMed , DOI )

  2. Koya Ono, Ken Murata, Toshinari Arai, Tomoyuki Kino, Keisuke Onaka, Satoru Takahashi, Hirotaka Sato, Hiroya Kuwahara: Posterior reversible encephalopathy syndrome after iron administration in a patient with chronic severe anemia. Journal of the Neurological Sciences. 2016.08; 367 333-334. ( PubMed , DOI )

  3. Hamaguchi Tsuyoshi, Taniguchi Yu, Sakai Kenji, Kitamoto Tetsuyuki, Takao Masaki, Murayama Shigeo, Iwasaki Yasushi, Yoshida Mari, Shimizu Hiroshi, Kakita Akiyoshi, Takahashi Hitoshi, Suzuki Hiroyoshi, Naiki Hironobu, Sanjo Nobuo, Mizusawa Hidehiro, Yamada Masahito: Significant association of cadaveric dura mater grafting with subpial A beta deposition and meningeal amyloid angiopathy ACTA NEUROPATHOLOGICA. 2016.08; 132 (2): 313-315. ( PubMed , DOI )

  4. Mitsuru Yoneyama,Hiroshi Mitoma,Nobuo Sanjo, Maya Higuma,Hiroo Terashi,Takanori Yokota: Ambulatory Gait Behavior in Patients with Dementia: A Comparison with Parkinson's Disease. Transactions on Neural System and Rehabilitation Engineering 2015 . 2016.08; 24 (8): 817-826. ( PubMed , DOI )

  5. Nobuo Sanjo,Satoko Kina,Yukiko Shishido-Hara,Yurie Nose,Satoru Ishibashi,Tetsuya Fukuda,Taketoshi Maehara,Yoshinobu Eishi,Hidehiro Mizusawa,Takanori Yokota: A Case of Progressive Multifocal Leukoencephalopathy with Balanced CD4/CD8 T-Cell Infiltration and Good Response to Mefloquine Treatment. Internal Medicine. 2016.01; 55 (12): 1631-1635. ( PubMed , DOI )

  6. Eric Vallabh Minikel,Sonia M. Vallabh,Monkol Lek,Karol O. Estrada,Kaitline E. Samocya,J. Fah Sathirapongsasuti,Cory Y. McLean,Joice Y. Tung,Linda P.C.Yu, Pierluigi Gambetti,Janis Blevins,Shuling Zhamg,Yvonne Cohen,Wei Chen,Masahito Yamada,Tsuyoshi Hamaguchi,Nobuo Sanjo,Hidehiro Mizusawa,Yoshikazu Nakamura,Tetsuyuki Kitamoto,Steven J. Collins,Alison Boyd,Robert G Will,Richard Knight,Claudia Ponto,Inga Zerr,Theo Kraus,Sabina Eigenbrod,Armin Giese,Jesus de Pedro Cuesta,Stéphane Haïk,Jean-Louis Laplanche,Jean Philippe Brandel,Michael Boenke,Markku Laakso,Karen Mohlke,Francis S.Collins,Anna Kähler,Kinberly Chambert, Steven McCarroll,Patrick Sullivan,Christina M. Hultman,Shaun M.Purcell,Pamela Sklar,Cornelia M.van Dujin,F.Rivadeneira Ramirez,Arfan Ikram,Sven J.van der Lee,Jeannette M.Vergeer-Drop,André G.Uitterlinden,Mark J.Daley,Daniel G.MacArthur,: Quantifying prion disease penetrance using large population control cohorts. Science Translational Medicine 2016. 2016.01; 8 (322): 322R9-322RA9. ( PubMed , DOI )

  7. Yutaro Asami, Kotaro Yoshioka, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota: Drug delivery system of therapeutic oligonucleotides. Drug Discov Ther. 2016; 10 (5): 256-262. ( PubMed , DOI )

  8. Ishimura Yuko, Tsukamoto Tadashi, Kuwata Kazuo, Yamada Masahito, Doh-ura Katsumi, Tsuboi Yoshio, Sato Katsuya, Nakamura Yoshikazu, Sanjo Nobuo, Tamura Chieko, Mizusawa Hidehiro: The Japan Consortium of Prion Disease (JACOP) for patients' registration and clinical studies of Prion diseases in Japan PRION. 2016; 10 S106-S107.

  9. Furukawa Fumiko, Sanjo Nobuo, Kobayashi Atsushi, Hamaguchi Tsuyoshi, Yamada Masahito, Kitamoto Tetsuyuki, Mizusawa Hidehiro, Yokota Takanori: Differential association of amyloid-beta with PrPSc pathology in each genetic prion disease PRION. 2016; 10 S85-S86.

  10. Yamada Masahito, Hamaguchi Tsuyoshi, Sakai Kenji, Nozaki Ichiro, Noguchi-Shinohara Moeko, Sanjo Nobuo, Tsukamoto Tadashi, Ae Ryusuke, Nakamura Yosikazu, Kitamoto Tetsuyuki, Mizusawa Hidehiro: Epidemiological and clinical features of human prion diseases in Japan: Prospective 17-year surveillance PRION. 2016; 10 S10-S11.

  11. Mitsuru Yoneyama, Hiroshi Mitoma, Nobuo Sanjo, Maya Higuma, Hiroo Terashi, Takanori Yokota: Ambulatory Gait Behavior in Patients with Dementia: A Comparison with Parkinson’s Disease. Transactions on Neural System and Rehabilitation Engineering. 2016; 24 (8): 817-826.

  1. Masahiro Murakami, Kazutaka Nishina, Chie Watanabe, Kie Yoshida-Tanaka, Wenying Piao, Hiroya Kuwahara, Yuji Horikiri, Kanjiro Miyata, Nobuhiro Nishiyama, Kazunori Kataoka, Masayuki Yoshida, Hidehiro Mizusawa, Takanori Yokota.: Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route. Scientific Reports. 2015.11; 5 17035. ( PubMed , DOI )

  2. Murai H., Nakamura Y., Kitamoto T., Tsuboi Y., Sanjo N., Yamada M., Mizusawa H., Kira J.: Clinical and epidemiological survey of gerstmann-strausslerscheinker disease with codon 102 mutation in Japan JOURNAL OF THE NEUROLOGICAL SCIENCES. 2015.10; 357 E114. ( DOI )

  3. Kazutaka Nishina, Wenying Piao, Kie Yoshida-Tanaka, Yumiko Sujino, Tomoko Nishina, Tsuyoshi Yamamoto, Keiko Nitta, Kotaro Yoshioka, Hiroya Kuwahara, Hidenori Yasuhara, Takeshi Baba, Fumiko Ono, Kanjiro Miyata, Koichi Miyake, Punit P Seth, Audrey Low, Masayuki Yoshida, C Frank Bennett, Kazunori Kataoka, Hidehiro Mizusawa, Satoshi Obika, Takanori Yokota: DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing. Nat Commun. 2015.08; 6 7969. ( PubMed , DOI )

  4. Hiroya Kuwahara, Kazutaka Nishina, Takanori Yokota.: Blood-brain barrier: a novel therapeutic target in multiple sclerosis. Clinical and Experimental Neuroimmunology.. 2015.05; 6 (2): 129-138. ( DOI )

  5. Yohsuke Yagi, Hiroaki Yokote, Yukiko Watanabe, Takeshi Amino, Tomoyuki Kamata, Susumu Kusunoki: Taste impairment in Miller Fisher syndrome. Neurol. Sci.. 2015.05; 36 (5): 809-810. ( PubMed , DOI )

  6. Ethan A Winkler, Yoichiro Nishida, Abhay P Sagare, Sanket V Rege, Robert D Bell, David Perlmutter, Jesse D Sengillo, Sara Hillman, Pan Kong, Amy R Nelson, John S Sullivan, Zhen Zhao, Herbert J Meiselman, Rosalinda B Wenby, Jamie Soto, E Dale Abel, Jacob Makshanoff, Edward Zuniga, Darryl C De Vivo, Berislav V Zlokovic: GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration. Nat. Neurosci.. 2015.04; 18 (4): 521-530. ( PubMed , DOI )

  7. Furukawa Fumiko, Sanjo Nobuo, Higuma Maya, Kitamoto Tetsuyuki, Hizume Masaki, Nakamura Yoshikazu, Yukamoto Tadashi, Murayama Shigeo, Koshi Kagari, Matsukawa Takashi, Tsuji Shoji, Goto Jun, Yamada Masahito, Mizusawa Hidehiro, Yokota Takanori: Clinical features in Gerstmann-Straussler-Scheinker syndrome with P105L mutation PRION. 2015.04; 9 S16.

  8. Minikel Eric Vallabh, Vallabh Sonia M., Lek Monkol, Estrada Karol O., Samocha Kaitlin E., Sathirapongsasuti J. Fah, McLean Cory Y., Tung Joyce Y., Yu Linda P. C., Gambetti Pierluigi, Blevins Janis, Zhang Shulin, Cohen Yvonne, Chen Wei, Yamada Masahito, Hamaguchi Tsuyoshi, Sanjo Nobuo, Mizusawa Hidehiro, Nakamura Yosikazu, Kitamoto Tetsuyuki, Collins Steven J., Boyd Alison, Will Robert G., Knight Richard, Ponto Claudia, Zerr Inga, Kraus Theo F. J., Eigenbrod Sabina, Giese Armin, Calero Miguel, de Pedro-Cuesta Jesus, Haik Stephane, Laplanche Jean-Louis, Bouaziz-Amar Elodie, Brandel Jean-Philippe, Capellari Sabina, Parchi Piero, O'Donnell-Luria Anne H., Karczewski Konrad J., Marshall Jamie L., Boehnke Michael, Laakso Markku, Mohlke Karen L., Kahler Anna, Chambert Kimberly, McCarroll Steven, Sullivan Patrick F., Hultman Christina M., Purcell Shaun M., Sklar Pamela, van der Lee Sven J., Rozemuller Annemieke, Jansen Casper, Hofman Albert, Kraaij Robert, van Rooij Jeroen G. J., Ikram M. Arfan, Uitterlinden Andre G., van Duijn Cornelia M., Daly Mark J., MacArthur Daniel G.: Assessing the pathogenicity of rare PRNP variants by comparing case and control allele frequency PRION. 2015.04; 9 S90-S91.

  9. Hamaguchi Tsuyoshi, Sakai Kenji, Noguchi-Shinohara Moeko, Nozaki Ichiro, Takumi Ichiro, Sanjo Nobuo, Nakamura Yosikazu, Kitamoto Tetsuyuki, Saito Nobuhito, Mizusawa Hidehiro, Yamada Masahito: A comparative study of dura mater graft-associated Creutzfeldt-Jakob disease between Japan and other countries PRION. 2015.04; 9 S23-S24.

  10. Tomoko Nishina, Junna Numata, Kazutaka Nishina, Kie Yoshida-Tanaka, Keiko Nitta, Wenying Piao, Rintaro Iwata, Shingo Ito, Hiroya Kuwahara, Takeshi Wada, Hidehiro Mizusawa, Takanori Yokota.: Chimeric Antisense Oligonucleotide Conjugated to α-Tocopherol. Mol Ther Nucleic Acids.. 2015.01; 4 e220. ( PubMed , DOI )

  11. Yoichiro Nishida, Akihiko Ueda, Yukio Ando, Tadashi Ichikawa: Skin Biopsy-based Diagnosis of CADASIL with Atypical MRI Findings. Intern. Med.. 2015; 54 (5): 537-538. ( PubMed , DOI )

  12. Daishi Yui, Yoichiro Nishida, Tomoko Nishina, Kaoru Mogushi, Mio Tajiri, Satoru Ishibashi, Itsuki Ajioka, Kinya Ishikawa, Hidehiro Mizusawa, Shigeo Murayama, Takanori Yokota: Enhanced Phospholipase A2 Group 3 Expression by Oxidative Stress Decreases the Insulin-Degrading Enzyme. PLoS ONE. 2015; 10 (12): e0143518. ( PubMed , DOI )

  13. Yosikazu Nakamaura, Ryusuke Ae, Ichiro Takumi, Nobuo Sanjo, Tetsuyuki Kitamoto, Masahito Yamada, Hidehiro Mizusawa. : Descriptive epidemiology of prion disease in Japan: 1999-2012. Journal of Epidemiology . 2015; 25 (1): 8-14.

  1. Kazuo Iwasa, Keisuke Shima, Kiyonobu Komai, Yoichiro Nishida, Takanori Yokota, Masahito Yamada: Retinitis pigmentosa and macular degeneration in a patient with ataxia with isolated vitamin E deficiency with a novel c.717 del C mutation in the TTPA gene. J. Neurol. Sci.. 2014.10; 345 (1-2): 228-230. ( PubMed , DOI )

  2. Yosikazu Nakamaura, Ryusuke Ae, Ichiro Takumi, Nobuo Sanjo, Tetsuyuki Kitamoto, Masahito Yamada, Hidehiro Mizusawa: Descriptive Epidemiology of Prion Disease in Japan: 1999-2012. J Epidemiol. 2014.10; ( PubMed )

  3. Fumiko Furukawa, Satoru Ishibashi, Nobuo Sanjo, Hiroshi Yamashita, Hidehiro Mizusawa: Serial magnetic resonance imaging changes in sporadic Creutzfeldt-Jakob disease with valine homozygosity at codon 129 of the prion protein gene. JAMA Neurol. 2014.09; 71 (9): 1186-1187. ( PubMed , DOI )

  4. Masahiko Ichijo, Satoru Ishibashi, Takuya Ohkubo, Shosaku Nomura, Nobuo Sanjo, Takanori Yokota, Hidehiro Mizusawa: Elevated platelet microparticle levels after acute ischemic stroke with concurrent idiopathic thrombocytopenic purpura. J Stroke Cerebrovasc Dis. 2014.03; 23 (3): 587-589. ( PubMed , DOI )

  5. Hirai Takashi, Enomoto Mitsuhiro, Kaburagi Hidetoshi, Sotome Shinichi, Yoshida-Tanaka Kie, Ukegawa Madoka, Kuwahara Hiroya, Yamamoto Mariko, Tajiri Mio, Miyata Haruka, Hirai Yukihiko, Tominaga Makoto, Shinomiya Kenichi, Mizusawa Hidehiro, Okawa Atsushi, Yokota Takanori.: Intrathecal AAV serotype 9-mediated delivery of shRNA against TRPV1 attenuates thermal hyperalgesia in a mouse model of peripheral nerve injury. Molecular Therapy.. 2014.02; 22 (2): 409-419. ( PubMed , DOI )

  6. Kuwahara Hiroya, Tsuchiya Kuniaki, Kobayashi Zen, Inaba Akira, Akiyama Haruhiko, Mizusawa Hidehiro.: Cryptococcal meningitis accompanying lymphocytic inflammation predominantly in cerebral deep white matter: a possible manifestation of immune reconstitution inflammatory syndrome. Neuropathology.. 2014.02; 34 (1): 45-48. ( PubMed , DOI )

  7. Teruhiko Sekiguchi, Tadashi Kanouchi, Kazumoto Shibuya, Yu-ichi Noto, Yohsuke Yagi, Akira Inaba, Keisuke Abe, Sonoko Misawa, Satoshi Orimo, Takayoshi Kobayashi, Tomoyuki Kamata, Masanori Nakagawa, Satoshi Kuwabara, Hidehiro Mizusawa, Takanori Yokota: Spreading of amyotrophic lateral sclerosis lesions--multifocal hits and local propagation? J. Neurol. Neurosurg. Psychiatr.. 2014.01; 85 (1): 85-91. ( PubMed , DOI )

  8. Furukawa Fumiko, Sanjo Nobuo, Kobayashi Atsushi, Kitamoto Tetsuyuki, Shiraishi Atsushi, Ishikawa Kinya, Honda Haruhisa, Yamada Masahito, Mizusawa Hidehiro: Clinical features of Gerstmann-Straussler-Scheinker syndrome with a P105L mutation and a valine-encoding polymorphic codon 129 in the prion protein gene PRION. 2014; 8 130-131.

  9. Yu Mizuno, Yasuhisa Sakurai, Izumi Sugimoto, Keiko Ichinose, Shoichiro Ishihara, Nobuo Sanjo, Hidehiro Mizusawa, Toru Mannen: Delayed leukoencephalopathy after carbon monoxide poisoning presenting as subacute dementia. Intern. Med.. 2014; 53 (13): 1441-1445. ( PubMed )

  10. Temu Qina, Nobuo Sanjo, Masaki Hizume, Maya Higuma, Makoto Tomita, Ryuichiro Atarashi, Katsuya Satoh, Ichiro Nozaki, Tsuyoshi Hamaguchi, Yosikazu Nakamura, Atsushi Kobayashi, Tetsuyuki Kitamoto, Shigeo Murayama, Hiroyuki Murai, Masahito Yamada, Hidehiro Mizusawa: Clinical features of genetic Creutzfeldt-Jakob disease with V180I mutation in the prion protein gene. BMJ Open. 2014; 4 (5): e004968. ( PubMed , DOI )

  11. Temu Qina, Nobuo Sanjo, Masaki Hizume, Maya Higuma, Makoto Tomita, Ryuichiro Atarashi, Katsuya Satoh, Ichiro Nozaki, Tsuyoshi Hamaguchi, Yosikazu Nakamura, Atsushi Kobayashi, Tetsuyuki Kitamoto, Shigeo Murayama, Hiroyuki Murai, Masahito Yamada, Hidehiro Mizusawa.: Clinical features of genetic Creutzfeldt-Jakob disease with V180I mutation in the prion protein gene. BMJ Open . 2014; 4 (5): e004968.

  1. Kuwahara Hiroya, Suzuki Shigeharu, Matsumura Ken, Watanabe Mutsufusa, Yakushiji Fumiatsu, Fujigasaki Hiroto.: Ocular flutter, generalized myoclonus, and truncal ataxia in a patient with Graves' ophthalmopathy. Journal of Neurology.. 2013.11; 260 (11): 2906-2907. ( PubMed , DOI )

  2. Tsuyoshi Hamaguchi, Kenji Sakai, Moeko Noguchi-Shinohara, Ichiro Nozaki, Ichiro Takumi, Nobuo Sanjo, Atsuko Sadakane, Yosikazu Nakamura, Tetsuyuki Kitamoto, Nobuhito Saito, Hidehiro Mizusawa, Masahito Yamada: Insight into the frequent occurrence of dura mater graft-associated Creutzfeldt-Jakob disease in Japan. J. Neurol. Neurosurg. Psychiatr.. 2013.10; 84 (10): 1171-1175. ( PubMed , DOI )

  3. Yohsuke Yagi, Yukiko Watanabe, Hiroaki Yokote, Takeshi Amino, Tomoyuki Kamata: Cervical dystonia in an Alzheimer's disease patient treated with donepezil. Acta Neurol Belg. 2013.09; 113 (3): 363-364. ( PubMed , DOI )

  4. Machida Akira, Kuwahara Hiroya, Mayra Azat, Kubodera Takayuki, Hirai Takashi, Sunaga Fumiko, Tajiri Mio, Hirai Yukihiko, Shimada Takashi, Mizusawa Hidehiro, Yokota Takanori.: Intraperitoneal administration of AAV9-shRNA inhibits target gene expression in the dorsal root ganglia of neonatal mice. Molecular Pain.. 2013.07; 9 36. ( PubMed , DOI )

  5. Hiroaki Yokote, Yohsuke Yagi, Yukiko Watanabe, Takeshi Amino, Tomoyuki Kamata, Hidehiro Mizusawa: Serum amyloid A level is increased in neuromyelitis optica and atypical multiple sclerosis with smaller T2 lesion volume in brain MRI. J. Neuroimmunol.. 2013.06; 259 (1-2): 92-95. ( PubMed , DOI )

  6. Yohsuke Yagi, Yukiko Watanabe, Hiroaki Yokote, Takeshi Amino, Tomoyuki Kamata: Transient Charles Bonnet syndrome in a patient with reversible cerebral vasoconstriction syndrome. Neurol. Sci.. 2013.06; 34 (6): 1023-1025. ( PubMed , DOI )

  7. Yohsuke Yagi, Yukiko Watanabe, Hiroaki Yokote, Takeshi Amino, Tomoyuki Kamata: Lacunar thalamic infarction with isolated dysesthesia in contralateral fingers. Acta Neurol Belg. 2013.06; 113 (2): 199-200. ( PubMed , DOI )

  8. Hiroya Kuwahara.: Persistent hemichorea. New England Journal of Medicine. 2013.05; 368 (20): e26. ( PubMed , DOI )

  9. Abhay P Sagare, Robert D Bell, Alaka Srivastava, Jesse D Sengillo, Itender Singh, Yoichiro Nishida, Nienwen Chow, Berislav V Zlokovic: A lipoprotein receptor cluster IV mutant preferentially binds amyloid-β and regulates its clearance from the mouse brain. J. Biol. Chem.. 2013.05; 288 (21): 15154-15166. ( PubMed , DOI )

  10. Piao Wenying, Nishina Kazutaka, Yoshida-Tanaka Kie, Kuwahara Hiroya, Nishina Tomoko, Sakata Mina, Mizusawa Hidehiro, Yokota Takanori: Efficient in vivo delivery of antisense oligonucleotide to choroid plexus. J Med Dent Sci. 2013.03; 60 (1): 9-16. ( PubMed )

  11. Kuwahara Hiroya, Matsumura Ken, Watanabe Mutsufusa, Fujigasaki Hiroto: Intravenous t-PA for the occlusion of an accessory MCA. Intern Med. 2013.01; 52 (1): 163. ( PubMed )

  12. Teruhiko Sekiguchi, Hiroyuki Tomimitsu, Teruhiko Sekiguchi, Yoichiro Nishida, Takashi Irioka, Akira Inaba, Yoshinobu Hoshii: ATTR amyloidosis complicated by phrenic nerve palsy. Can J Neurol Sci. 2013.01; 40 (1): 129-130. ( PubMed )

  13. Zen Kobayashi, Miho Akaza, Yoshiyuki Numasawa, Shoichiro Ishihara, Hiroyuki Tomimitsu, Kazuo Nakamichi, Masayuki Saijo, Tomohiro Morio, Norio Shimizu, Nobuo Sanjo, Shuzo Shintani, Hidehiro Mizusawa: Failure of mefloquine therapy in progressive multifocal leukoencephalopathy: report of two Japanese patients without human immunodeficiency virus infection. J. Neurol. Sci.. 2013.01; 324 (1-2): 190-194. ( PubMed , DOI )

  14. Masaki Ohyagi, Takuya Ohkubo, Yousuke Yagi, Satoru Ishibashi, Junko Akiyama, Masakazu Nagahori, Mamoru Watanabe, Takanori Yokota, Hidehiro Mizusawa: Chronic inflammatory demyelinating polyradiculoneuropathy in a patient with Crohn's disease. Intern. Med.. 2013; 52 (1): 125-128. ( PubMed )

  15. Yohsuke Yagi, Nobuo Sanjo, Takanori Yokota, Hidehiro Mizusawa: Tacrolimus monotherapy: a promising option for ocular myasthenia gravis. Eur. Neurol.. 2013; 69 (6): 344-345. ( PubMed , DOI )

  16. Teruhiko Sekiguchi, Yoichiro Nishida, Akira Inaba, Shigeo Toyota: Mesothelioma-mimicking multiple myeloma with dumbbell-type progression. Intern. Med.. 2013; 52 (11): 1287-1288. ( PubMed )

  17. Kazunori Sano, Katsuya Satoh, Ryuichiro Atarashi, Hiroshi Takashima, Yasushi Iwasaki, Mari Yoshida, Nobuo Sanjo, Hiroyuki Murai, Hidehiro Mizusawa, Matthias Schmitz, Inga Zerr, Yong-Sun Kim, Noriyuki Nishida: Early detection of abnormal prion protein in genetic human prion diseases now possible using real-time QUIC assay. PLoS ONE. 2013; 8 (1): e54915. ( PubMed , DOI )

  18. Maya Higuma, Nobuo Sanjo, Katsuya Satoh, Yusei Shiga, Kenji Sakai, Ichiro Nozaki, Tsuyoshi Hamaguchi, Yosikazu Nakamura, Tetsuyuki Kitamoto, Susumu Shirabe, Shigeo Murayama, Masahito Yamada, Jun Tateishi, Hidehiro Mizusawa: Relationships between clinicopathological features and cerebrospinal fluid biomarkers in Japanese patients with genetic prion diseases. PLoS ONE. 2013; 8 (3): e60003. ( PubMed , DOI )

  19. Takumi Hori, Nobuo Sanjo, Makoto Tomita, Hidehiro Mizusawa: Visual Reproduction on the Wechsler Memory Scale-Revised as a predictor of Alzheimer's disease in Japanese patients with mild cognitive impairments. Dement Geriatr Cogn Disord. 2013; 35 (3-4): 165-176. ( PubMed , DOI )

  20. Kenji Sakai, Tsuyoshi Hamaguchi, Moeko Noguchi-Shinohara, Ichiro Nozaki, Ichiro Takumi, Nobuo Sanjo, Yosikazu Nakamura, Tetsuyuki Kitamoto, Nobuhito Saito, Hidehiro Mizusawa, Masahito Yamada: Graft-related disease progression in dura mater graft-associated Creutzfeldt-Jakob disease: a cross-sectional study. BMJ Open. 2013; 3 (8): e003400. ( PubMed , DOI )

  21. Kenji Sakai, Tsuyoshi Hamaguchi, Moeko Noguchi-Shinohara, Ichiro Nozaki, Ichiro Takumi, Nobuo Sanjo, Yosikazu Nakamura, Tetsuyuki Kitamoto, Nobuhito Saito, Hidehiro Mizusawa, Masahito Yamada.: Graft-related disease progression in dura mater graft-associated Creutzfeldt-Jakob disease: a cross-sectional study. BMJ Open. 2013; 3 (8): e003400.

  22. Kazunori Sano, Katsuya Satoh, Ryuichiro Atarashi, Hiroshi Takashima, Yasushi Iwasaki, Mari Yoshida, Nobuo Sanjo, Hiroyuki Murai, Hidehiro Mizusawa, Matthias Schmitz, Inga Zerr, Yong-Sun Kim, Noriyuki Nishida.: Early Detection of Abnormal Prion Protein in Genetic Human Prion Diseases Now Possible Using Real-Time QUIC Assay. PLoS One. 2013; 8 (1): e54915.

  23. Maya Higuma, Nobuo Sanjo, Katsuya Satoh, Yusei Shiga, Kenji Sakai, Ichiro Nozaki, Tsuyoshi Hamaguchi, Yosikazu Nakamura, Tetsuyuki Kitamoto, Susumu Shirabe, Shigeo Murayama, Masahito Yamada, Jun Tateishi, Hidehiro Mizusawa.: Relationships between Clinicopathological Features and Cerebrospinal Fluid Biomarkers in Japanese Patients with Genetic Prion Diseases. PLoS One. 2013; 8 (3): e60003.

  24. Takumi Hori, Nobuo Sanjo, Makoto Tomita, Hidehiro Mizusawa. : Visual Reproduction on the Wechsler Memory Scale-Revised as a predictor of Alzheimer’s disease in Japanese patients with mild cognitive impairments. Dementia and Geriatric Cognitive Disorders. 2013; 35 165-176.

  1. Yohsuke Yagi, Akira Machida, Shuta Toru, Takayoshi Kobayashi, Tomonari Amano, Katsuiku Hirokawa, Masanobu Kitagawa: Myotonic dystrophy and lipoma: a new association. Neurol. Sci.. 2012.12; 33 (6): 1477-1478. ( PubMed , DOI )

  2. 三條 伸夫, Qina Temu, 日熊 麻耶, Fraser Paul, 水澤 英洋: アミロイドβ産生に及ぼすI143Tの変異を持つPSEN1の影響(An Effect of PSEN1 with I143T Mutation on Amyloid β Production) Dementia Japan. 2012.10; 26 (4): 515. ( ichushi )

  3. Masaki Ohyagi, Nobuo Sanjo, Takanori Yokota, Hidehiro Mizusawa: Hereditary neuropathy with liability to pressure palsy combined with suspected schwannomas of the peroneal and radial nerves. J. Neurol.. 2012.05; 259 (5): 977-979. ( PubMed , DOI )

  4. Hirai Takashi, Enomoto Mitsuhiro, Machida Akira, Yamamoto Mariko, Kuwahara Hiroya, Tajiri Mio, Hirai Yukihiko, Sotome Shinichi, Mizusawa Hidehiro, Shinomiya Kenichi, Okawa Atsushi, Yokota Takanori: Intrathecal shRNA-AAV9 inhibits target protein expression in the spinal cord and dorsal root ganglia of adult mice. Hum Gene Ther Methods. 2012.04; 23 (2): 119-127. ( PubMed , DOI )

  5. Kuwahara Hiroya, Yokota Takanori: Delivery of siRNA into the blood-brain barrier: recent advances and future perspective. Ther Deliv. 2012.04; 3 (4): 417-420. ( PubMed )

  6. Kuwahara Hiroya, Matsunaga Shin-ichi: Central pontine myelinolysis associated with pancreatic diabetes. J Neurol. 2012.02; 259 (2): 353-354. ( PubMed , DOI )

  7. Yoichiro Nishida, Tadashi Ichikawa: Pontine hyperperfusion during recovery from central pontine myelinolysis. Intern. Med.. 2012; 51 (7): 817-818. ( PubMed )

  8. Sanjo Nobuo: Clinical features of genetic prion disease and cerebrospinal fluid findings in Japanese patients PRION. 2012; 6 128.

  9. Koji Fujita, Masafumi Harada, Makoto Sasaki, Tatsuhiko Yuasa, Kenji Sakai, Tsuyoshi Hamaguchi, Nobuo Sanjo, Yusei Shiga, Katsuya Satoh, Ryuichiro Atarashi, Susumu Shirabe, Ken Nagata, Tetsuya Maeda, Shigeo Murayama, Yuishin Izumi, Ryuji Kaji, Masahito Yamada, Hidehiro Mizusawa: Multicentre multiobserver study of diffusion-weighted and fluid-attenuated inversion recovery MRI for the diagnosis of sporadic Creutzfeldt-Jakob disease: a reliability and agreement study. BMJ Open. 2012; 2 (1): e000649. ( PubMed , DOI )

  10. Koji Fujita, Masafumi Harada, Makoto Sasaki, Tatsuhiko Yuasa, Kenji Sakai, Tsuyoshi Hamaguchi, Nobuo Sanjo, Yusei Shiga, Katsuya Satoh, Ryuichiro Atarashi, Susumu Shirabe, Ken Nagata, Tetsuya Maeda, Shigeo Murayama, Yuishin Izumi, Ryuji Kaji, Masahito Yamada, Hidehiro Mizusawa. : Multicentre, multiobserver study of diffusion-weighted and fluid-attenuated inversion recovery MRI for the diagnosis of sporadic Creutzfeldt–Jakob disease: a reliability and agreement study. BMJ open. 2012; 2 e000649.

  1. Yoko Ito,Nobuo Sanjo,Kinya Ishikawa,Osamu Tao,Takanori Yokota,Hidehiro Mizusawa: Brainstem congestion due to carotid-cavernous fistula via a shunt from the external calotid artery. Journal of Neurology . 2011.12; (258): 2288-2290. ( PubMed , DOI )

  2. Kuwahara H, Nishina K, Yoshida K, Nishina T, Yamamoto M, Saito Y, Piao W, Yoshida M, Mizusawa H, Yokota T: Efficient in vivo delivery of siRNA into brain capillary endothelial cells along with endogenous lipoprotein. Mol Ther. 2011.12; 19 (12): 2213-2221. ( PubMed , DOI )

  3. Yohsuke Yagi, Akira Machida, Shuta Toru, Takayoshi Kobayashi, Toshiki Uchihara: Sialidosis type I with neoplasms in siblings: the first clinical cases. Neurol. Sci.. 2011.08; 32 (4): 737-738. ( PubMed , DOI )

  4. Kuwahara Hiroya, Nakatsuru Enichi, Ozawa Naoko: Exertional rhabdomyolysis affecting anterior compartment of unilateral lower leg. Intern Med. 2011.04; 50 (7): 793. ( PubMed )

  1. Kuwahara Hiroya, Noguchi Yoshimasa, Saito Yukinobu, Inaba Akira: Multiple cavernous angiomas in the brain and spinal cord. Arch Neurol. 2010.11; 67 (11): 1405-1406. ( PubMed , DOI )

  2. Kuwahara Hiroya, Tsuchiya Kuniaki, Saito Yukinobu, Kobayashi Zen, Miyazaki Hiroshi, Izumiyama Yoko, Akiyama Haruhiko, Arai Tetsuaki, Mizusawa Hidehiro: Frontotemporal lobar degeneration with motor neuron disease showing severe and circumscribed atrophy of anterior temporal lobes. J Neurol Sci. 2010.10; 297 (1-2): 92-96. ( PubMed , DOI )

  3. Nobuo Sanjo, Taiichi Katayama, Hiroshi Hasegawa, Haifeng Jin, Monika Duthie, Howard T J Mount, Hidehiro Mizusawa, Peter St George-Hyslop, Paul E. Fraser: Localization and trafficking of endogenous anterior pharynx-defective 1, a component of Alzheimer's disease related gamma-secretase. Neurosci. Lett.. 2010.10; 483 (1): 53-56. ( PubMed , DOI )

  4. Ichiro Nozaki, Tsuyoshi Hamaguchi, Nobuo Sanjo, Moeko Noguchi-Shinohara, Kenji Sakai, Yosikazu Nakamura, Takeshi Sato, Tetsuyuki Kitamoto, Hidehiro Mizusawa, Fumio Moriwaka, Yusei Shiga, Yoshiyuki Kuroiwa, Masatoyo Nishizawa, Shigeki Kuzuhara, Takashi Inuzuka, Masatoshi Takeda, Shigetoshi Kuroda, Koji Abe, Hiroyuki Murai, Shigeo Murayama, Jun Tateishi, Ichiro Takumi, Susumu Shirabe, Masafumi Harada, Atsuko Sadakane, Masahito Yamada: Prospective 10-year surveillance of human prion diseases in Japan. Brain. 2010.10; 133 (10): 3043-3057. ( PubMed , DOI )

  5. Yoichiro Nishida, Takashi Irioka, Teruhiko Sekiguchi, Hidehiro Mizusawa: Pure sensory infarct in the territories of anterior cerebral artery. Neurology. 2010.07; 75 (3): 287. ( PubMed , DOI )

  6. Haifeng Jin, Nobuo Sanjo, Toshiki Uchihara, Kazuhiko Watabe, Peter St George-Hyslop, Paul E Fraser, Hidehiro Mizusawa: Presenilin-1 holoprotein is an interacting partner of sarco endoplasmic reticulum calcium-ATPase and confers resistance to endoplasmic reticulum stress. J. Alzheimers Dis.. 2010; 20 (1): 261-273. ( PubMed , DOI )

  7. Nobuo Sanjo, Taiichi Katayama, Hiroshi Hasegawa, Haifeng Jin, Monika Duthie, Howard T.J. Mount, Hidehiro Mizusawa, Peter St George-Hyslop, Paul E. Fraser. : Localization and trafficking of endogenous anterior pharynx-defective 1, a component of Alzheimer's disease related γ-secretase. Neuroscience Lett 2010; 483(1): 53-56. 2010; 483 (1): 53-56.

  8. 三條伸夫, 佐々木真理, 水澤英洋, プリオン病画像小委員会: 脳外科手術によるCJDリスク保因可能性者事例の経過と注意すべきプリオン病画像診断のポイント. CI研究. 2010; 31 (4): 233-239.

  9. Ichiro Nozaki, Tsuyoshi Hamaguchi, Nobuo Sanjo, Kenji Sakai, Moeko Noguchi-Shinohara, Yosikazu Nakamura, Takeshi Sato, Tetsuyuki Kitamoto, Hidehiro Mizusawa, Fumio Moriwaka, Yusei Shiga, Yoshiyuki Kuroiwa, Masatoyo Nishizawa, Shigeki Kuzuhara, Takashi Inuzuka, Masatoshi Takeda, Shigetoshi Kuroda, Koji Abe, Hiroyuki Murai, Shigeo Murayama, Jun Tateishi, Ichiro Takumi, Susumu Sirabe, Masafumi Harada, Masahito Yamada. : Prospective 10-years surveillance for human prion diseases in Japan. Brain 133(10); 2010, 3043-57. 2010; 133 (10): 3043-3057.

  1. Yoichiro Nishida, Shingo Ito, Sumio Ohtsuki, Naoki Yamamoto, Tsubura Takahashi, Nobuhisa Iwata, Kou-Ichi Jishage, Hiromi Yamada, Hiroki Sasaguri, Shigefumi Yokota, Wenying Piao, Hiroyuki Tomimitsu, Takaomi C Saido, Katsuhiko Yanagisawa, Tetsuya Terasaki, Hidehiro Mizusawa, Takanori Yokota: Depletion of vitamin E increases amyloid beta accumulation by decreasing its clearances from brain and blood in a mouse model of Alzheimer disease. J. Biol. Chem.. 2009.11; 284 (48): 33400-33408. ( PubMed , DOI )

  2. Takashi Irioka, Ayaka Yamanami, Yohsuke Yagi, Hidehiro Mizusawa: Aortic dissection as a possible cause of pure transient global amnesia: a case report and literature review. Neurol. Sci.. 2009.06; 30 (3): 255-258. ( PubMed , DOI )

  3. Yoichiro Nishida, Yuki Saito, Takanori Yokota, Takashi Kanda, Hidehiro Mizusawa: Skeletal muscle MRI in complex regional pain syndrome. Intern. Med.. 2009; 48 (4): 209-212. ( PubMed )

  1. Katayama Taiichi, Sanjo Nobuo, Fraser Paul, George-Hyslop Peter St., Sato Kohji: インビボクロスリンク法を用いたガンマセクレターゼ新規構成蛋白質の探索(A screening for novel components of gamma-secretase complex using by in vivo crosslink method) 神経化学. 2007.08; 46 (2-3): 484. ( ichushi )

  2. Yoichiro Nishida, Hiroshi Komachi, Hidehiro Mizusawa: A case of Listeria meningitis associated with increased adenosine deaminase in cerebrospinal fluid. Diagn. Microbiol. Infect. Dis.. 2007.04; 57 (4): 435-437. ( PubMed , DOI )

  3. Shiraishi Atsushi, Hino Taro, Kyodo Toride, Sanjo Nobuo, Ishibashi Satoru, Machida Akira, Mizutani Saneyuki, Shintani Shuzo, Mizusawa Hidehiro: Dual-plane diffusion-weighted imaging can improve the detection of diffusion-restricted lesions in patients who were suspected of stroke with mild severity: Axial and coronal DWI for acute stroke (ACORDAS) study STROKE. 2007.02; 38 (2): 495.

  1. Yoichiro Nishida, Takanori Yokota, Tsubura Takahashi, Toshiki Uchihara, Kou-ichi Jishage, Hidehiro Mizusawa: Deletion of vitamin E enhances phenotype of Alzheimer disease model mouse. Biochem. Biophys. Res. Commun.. 2006.11; 350 (3): 530-536. ( PubMed , DOI )

  2. Yong-Ri Ren, Yoichiro Nishida, Kenji Yoshimi, Toru Yasuda, Kou-Ichi Jishage, Toshiki Uchihara, Takanori Yokota, Yoshikuni Mizuno, Hideki Mochizuki: Genetic vitamin E deficiency does not affect MPTP susceptibility in the mouse brain. J. Neurochem.. 2006.09; 98 (6): 1810-1816. ( PubMed , DOI )

  3. Fusheng Chen, Hiroshi Hasegawa, Gerold Schmitt-Ulms, Toshitaka Kawarai, Christopher Bohm, Taiichi Katayama, Yongjun Gu, Nobuo Sanjo, Michael Glista, Ekaterina Rogaeva, Yosuke Wakutani, Raphaëlle Pardossi-Piquard, Xueying Ruan, Anurag Tandon, Frédéric Checler, Philippe Marambaud, Kirk Hansen, David Westaway, Peter St George-Hyslop, Paul Fraser: TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity. Nature. 2006.04; 440 (7088): 1208-1212. ( PubMed , DOI )

  4. Toshiki Uchihara, Nobuo Sanjo, Ayako Nakamura, Kyung Han, Si-Young Song, Peter St George-Hyslop, Paul E Fraser: Transient abundance of presenilin 1 fragments/nicastrin complex associated with synaptogenesis during development in rat cerebellum. Neurobiol. Aging. 2006.01; 27 (1): 88-97. ( PubMed , DOI )

  5. Uchihara T, Sanjo N, Nakamura A, Han K, Song SY, St George-Hyslop P, Fraser P.: Transient abundance of presenilin 1 fragments/nicastrin complex associated with synaptogenesis during development in rat cerebellum. Neurobiol Aging . 2006; 27 (1): 88-97.

  1. Agnes Petit, Toshitaka Kawarai, Erwan Paitel, Nobuo Sanjo, Mary Maj, Michael Scheid, Fusheng Chen, Yongjun Gu, Hiroshi Hasegawa, Shabnam Salehi-Rad, Linda Wang, Ekaterina Rogaeva, Paul Fraser, Brian Robinson, Peter St George-Hyslop, Anurag Tandon: Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations. J. Biol. Chem.. 2005.10; 280 (40): 34025-34032. ( PubMed , DOI )

  2. Koyama Rikako, Nakanishi Koji, Kato Masako, Yamashita Shigeo, Kuwahara Hiroya, Katori Hideyuki: Hypoglycemia and hyperglycemia due to insulin antibodies against therapeutic human insulin: treatment with double filtration plasmapheresis and prednisolone. Am J Med Sci. 2005.05; 329 (5): 259-264. ( PubMed )

  3. Petit A, Kawarai T, Paitel E, Sanjo N, Maj M, Scheid M, Chen F, Gu Y, Hasegawa H, Salehi-Rad S, Wang L, Rogaeva E, Fraser P, Robinson B, St George-Hyslop P, Tandon A (2005): Wild-type PINK1 Prevents Basal and Induced Neuronal Apoptosis, a Protective Effect Abrogated by Parkinson Disease-related Mutations. J Biol Chem. 2005; 280 34025-34032.

  1. Y Nishida, N Sodeyama, Y Toru, S Toru, T Kitamoto, H Mizusawa: Creutzfeldt-Jakob disease with a novel insertion and codon 219 Lys/Lys polymorphism in PRNP. Neurology. 2004.11; 63 (10): 1978-1979. ( PubMed )

  2. Hiroshi Hasegawa, Nobuo Sanjo, Fusheng Chen, Yong-Jun Gu, Cortney Shier, Agnes Petit, Toshitaka Kawarai, Taiichi Katayama, Stephen D Schmidt, Paul M Mathews, Gerold Schmitt-Ulms, Paul E Fraser, Peter St George-Hyslop: Both the sequence and length of the C terminus of PEN-2 are critical for intermolecular interactions and function of presenilin complexes. J. Biol. Chem.. 2004.11; 279 (45): 46455-46463. ( PubMed , DOI )

  3. Yongjun Gu, Nobuo Sanjo, Fusheng Chen, Hiroshi Hasegawa, Agnes Petit, Xueying Ruan, Wenping Li, Cortney Shier, Toshitaka Kawarai, Gerold Schmitt-Ulms, David Westaway, Peter St George-Hyslop, Paul E Fraser: The presenilin proteins are components of multiple membrane-bound complexes that have different biological activities. J. Biol. Chem.. 2004.07; 279 (30): 31329-31336. ( PubMed , DOI )

  4. Sumio Ishiai, Yasumasa Koyama, Naomi Nakano, Keiko Seki, Yoichiro Nishida, Kazuko Hayashi: Image of a line is not shrunk but neglected. Absence of crossover in unilateral spatial neglect. Neuropsychologia. 2004; 42 (2): 251-256. ( PubMed )

  5. Hasegawa H, Sanjo N, Chen F, Gu YJ, Shier C, Petit A, Kawarai, T., Katayama, T., Schmidt, S. D., Mathews, P. M., Schmitt-Ulms, G., Fraser, P. E., St George-Hyslop, P. : Both the sequence and length of the C-terminus of PEN-2 are critical for intermolecular interactions and function of presenilin complexes. Journal of Biological Chemistry . 2004; 279 (45): 46455-46463.

  6. Gu Y*, Sanjo N*, Chen F*, Hasegawa H, Petit A, Ruan X, Li, W., Shier, C., Kawarai, T., Schmitt-Ulms, G., Westaway, D., St George-Hyslop, P., Fraser, P. E. (*: equally contributed): The presenilin proteins are components of multiple membrane-bound complexes which have different biological activities. Journal of Biological Chemistry . 2004; 279 (30): 31329-31336.

  1. Fusheng Chen, Anurag Tandon, Nobuo Sanjo, Yong-Jun Gu, Hiroshi Hasegawa, Shigeki Arawaka, Frank J S Lee, Xueying Ruan, Peter Mastrangelo, Serap Erdebil, Linda Wang, David Westaway, Howard T J Mount, Bruce Yankner, Paul E Fraser, Peter St George-Hyslop: Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brain. J. Biol. Chem.. 2003.05; 278 (22): 19974-19979. ( PubMed , DOI )

  2. Kazuko Aoki, Toshiki Uchihara, Nobuo Sanjo, Ayako Nakamura, Kenji Ikeda, Kuniaki Tsuchiya, Yoshihiro Wakayama: Increased expression of neuronal apolipoprotein E in human brain with cerebral infarction. Stroke. 2003.04; 34 (4): 875-880. ( PubMed , DOI )

  3. Yongjun Gu, Fusheng Chen, Nobuo Sanjo, Toshitaka Kawarai, Hiroshi Hasegawa, Monica Duthie, Wenping Li, Xueying Ruan, Anchla Luthra, Howard T J Mount, Anurag Tandon, Paul E Fraser, Peter St George-Hyslop: APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin.nicastrin complexes. J. Biol. Chem.. 2003.02; 278 (9): 7374-7380. ( PubMed , DOI )

  4. Aoki K., Uchihara T., Sanjo N., Nakamura A., Ikeda K., Tsuchiya K. and Wakayama Y. : Increased Expression of Neuronal Apolipoprotein E in Human Brain With Cerebral Infarction. Stroke 2003; 34: 875-80.. 2003; 34 875-880.

  5. Chen F., Tandon A., Sanjo N., Gu Y. J., Hasegawa H., Arawaka S., Lee F. J., Ruan X., Mastrangelo P., Erdebil S., Wang L., Westaway D., Mount H. T., Yankner B., Fraser P. E. and St George-Hyslop P. : Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in mammalian brain. Journal of Biological Chemistry. 2003; 278 (22): 19974-19979.

  6. Gu Y, Chen F, Sanjo N, Kawarai T, Hasegawa H, Duthie M, Li W, Ruan X, Luthra A, Mount HT, Tsndon A, Fraser PE and St. George-Hyslop P. : APH-1 Interacts with Mature and Immature Forms of Presenilins and Nicastrin and May Play a Role in Maturation of Presenilin-Nicastrin Complexes Journal of Biological Chemistry. 2003; 278 7374-7380.

  1. Y Nishida, M Yamada, K Hara, T Tsunemi, M Yamawaki, R Shimokawa, R Okeda, T Tsutsumi, H Mizusawa: Creutzfeldt-Jakob disease after Jannetta's operation with cadaveric dura mater graft: initial manifestations related to the grafted site. J. Neurol.. 2002.04; 249 (4): 480-483. ( PubMed , DOI )

  1. 三條　伸夫, 上原　晋, 井浦　泰夫, 松本　卓, 市川　忠.: ＭＲＩ上椎骨・脳底動脈領域血管に異常を有する脳血管障害患者における未破裂脳動脈瘤保有率の検討. リハビリテーション医学. 2000; 37 165-170.

  1. K Owada, N Sanjo, T Kobayashi, H Mizusawa, H Muramatsu, T Muramatsu, M Michikawa: Midkine inhibits caspase-dependent apoptosis via the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase in cultured neurons. J. Neurochem.. 1999.11; 73 (5): 2084-2092. ( PubMed )

  2. Owada K, Sanjo N, Kobayashi T, Mizusawa H, Muramatsu H, Muramatsu T, Michikawa M.: Midkine inhibits Caspase-dependent apoptosis via the activation of Mitogen-activated protein kinase and phosphatidylinositol 3-kinase in cultured neurons. Journal of Neurochemistory . 1999; 73 (5): 2084-2092.

  3. Owada K, Sanjo N, Kobayashi T, Kamata T, Mizusawa H, Muramatsu H, Muramatsu T and Michikawa M. : Midkine inhibits apoptosis via extracellular signal regulated kinase (ERK) activation in PC12 cells. Journal of Medical and Dental Science . 1999; 46 45-51.

  1. N Sanjo, K Owada, T Kobayashi, H Mizusawa, A Awaya, M Michikawa: A novel neurotrophic pyrimidine compound MS-818 enhances neurotrophic effects of basic fibroblast growth factor. J. Neurosci. Res.. 1998.12; 54 (5): 604-612. ( PubMed )

  1. N Sanjo, T Yokota, Y Saitou, H Miake, H Tanaka: Painful bilateral abducens nerve palsy associated with anti-neutrophil cytoplasmic autoantibodies. J. Neurol.. 1996.08; 243 (8): 612-613. ( PubMed )

  1. Takanori Yokota, Kazutaka Nishina, Hiroya Kuwahara: Gene Therapy with therapeutic oligonucleotides Neurological Therapeutics. 2016.11; 33 (3): 303-306.

  1. Kazutaka Nishina, Kotaro Yoshioka, Hiroya Kuwahara, Takanori Yokota.: Gene therapy for neurological disorder using therapeutic oligonucleotides. Neurological Medicine. 2015.10; 83 (4): 283-288.

  2. Hiroya Kuwahara, Takanori Yokota.: Nano-DDS for oligonucleotide therapeutics. Cell Technology. 2015.10; 34 (10): 939-945.

  3. Hiroya Kuwahara, Toshiki Uchihara, Mitsuru Kawamura.: An autopsy case of amyotrophic lateral sclerosis presenting with flail arm syndrome and rapid progression of respiratory failure. Brain Nerve.. 2015.05; 67 (5): 639-650.

  1. Hiroya Kuwahara, Kazutaka Nishina, Takanori Yokota.: Drug delivery system for nucleic acie therapeutics. 2014.02; 40 (2): 19-22.

  1. Nobuo Sanjo, Hidehiro Mizusawa: [Prion disease--the characteristics and diagnostic points in Japan]. Clinical Neurology. 2010.05; 50 (5): 287-300. ( PubMed )

  1. Hiroya Kuwahara, Yoshimasa Noguchi, Akira Inaba, Hidehiro Mizusawa: Case of an 81-year-old woman with theophylline-associated seizures followed by partial seizures due to vitamin B6 deficiency. Rinsho Shinkeigaku. 2008.02; 48 (2): 125-129. ( PubMed )

  1. Nobuo Sanjo: [Acquired Creutzfeldt-Jakob disease (CJD)--Kuru, iatrogenic CJD, variant CJD]. 2007.08; 65 (8): 1438-1445. ( PubMed )

  1. Zeniya S, Kuwahara H, Daizo K, Watari A, Kondoh M, Yoshida-Tanaka K, Kaburagi H, Asada K, Nagata T, Nagahama M, Yagi K, Yokota T: Angubindin-1 opens the blood-brain barrier in vivo for delivery of antisense oligonucleotide to the central nervous system. Journal of controlled release : official journal of the Controlled Release Society. 2018.05; 283 126-134. ( PubMed , DOI )

  1. Yoshioka K, Kuwahara H, Nishina K, Nagata T, Yokota T: [Recent progress and prospect in oligonucleotide therapeutics]. Nihon rinsho. Japanese journal of clinical medicine. 2015.06; 73 (6): 1057-1065. ( PubMed )

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