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Incidence of Central Nervous System Toxicity and Cytokine Release Syndrome in Leukemia Patients Treated with Blinatumomab 2022.11; 140 11663-11665. ( DOI )
Outcomes of Older Patients with Aplastic Anemia Treated with Frontline Anti-Thymocyte Globulin (ATG)-Based Immunosuppressive Therapy 2022.11; 140 8652-8654. ( DOI )
Improved Outcomes with Low-Dose Inotuzumab and Mini-Hyper-CVD Followed By Blinatumomab Consolidation in Relapsed-Refractory Acute Lymphoblastic Leukemia: Results of a Phase II Study 2022.11; 140 11698-11701. ( DOI )
Prognostic Model of Transformation to Blast Phase in Patients with Chronic Myeloid Leukemia 2022.11; 140 3895-3896. ( DOI )
Long-Term Follow-up of Low-Dose Dasatinib (50mg Daily) As Frontline Therapy in Newly Diagnosed Chronic Myeloid Leukemia 2022.11; 140 1493-1494. ( DOI )
Phase I/II Study of Azacitidine (AZA) with Venetoclax (VEN) and Magrolimab (Magro) in Patients (pts) with Newly Diagnosed (ND) Older/Unfit or High-Risk Acute Myeloid Leukemia (AML) and Relapsed/Refractory (R/R) AML 2022.11; 140 ( DOI )
A Descriptive Analysis of TP53 Y220C Mutations in Patients with Hematologic Malignancies 2022.11; 140 11830-11832. ( DOI )
More Than Ten Years Follow-up of Frontline Tyrosine Kinase Inhibitor Therapy in Patients with Chronic Myeloid Leukemia 2022.11; 140 3897-3899. ( DOI )
A Phase I/II Study of Combination of Azacitidine, Venetoclax and Pevonedistat in Patients with Newly-Diagnosed Secondary Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) with Hypomethylating Agent (HMA) Failure 2022.11; 140 6206-6208. ( DOI )
A Phase II Study of Azacitidine Plus Venetoclax As Maintenance Therapy in Acute Myeloid Leukemia: Durable Responses with Longer Term Follow- 2022.11; 140 9005-9007. ( DOI )
A Phase II Study of the Combination of Decitabine, Venetoclax and Ponatinib in Patients with Chronic Myeloid Leukemia (CML) in Myeloid Blast Phase (MBP) or Philadelphia-Chromosome Positive (Ph plus ) Acute Myeloid Leukemia (AML) 2022.11; 140 3880-3882. ( DOI )
Myelodysplastic Syndromes without Detectable Mutations: Analysis of Clinical Presentation and Outcome 2022.11; 140 9793-9795. ( DOI )
A Phase II Study of Inotuzumab Ozogamicin for the Treatment of Measurable Residual Disease-Positive B-Cell Acute Lymphoblastic Leukemia 2022.11; 140 3253-3255. ( DOI )
A Suboptimal Response in CML Is Associated with Expression of the Immune Checkpoint VISTA 2022.11; 140 6739-6741. ( DOI )
Activity of menin inhibitor ziftomenib (KO-539) as monotherapy or in combinations against AML cells with MLL1 rearrangement or mutant NPM1. 2022.11; 36 (11): 2729-2733. ( PubMed , DOI )
ASC2ESCALATE: A Phase 2, Single-Arm, Dose-Escalation Study of Asciminib Monotherapy in Patients (Pts) with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) Previously Treated with 1 Prior Tyrosine Kinase Inhibitor (TKI) 2022.11; 140 6784-6786. ( DOI )
Aplastic anemia following the severe acute respiratory syndrome coronavirus-2 vaccine. 2022.11; 4 (1): 288-90. ( PubMed , DOI )
Combined Ibrutinib and Venetoclax for First-Line Treatment of Patients with Chronic Lymphocytic Leukemia (CLL): 4-Year Follow-up Data 2022.11; 140 ( DOI )
Combined Structural Variant and Mutation Profiling for Comprehensive Characterization of Chromoanagenesis and TP53 Mutations in Myelodysplastic Syndromes with Complex Karyotype 2022.11; 140 7844-7845. ( DOI )
Contemporary outcomes in IDH-mutated acute myeloid leukemia: The impact of co-occurring NPM1 mutations and venetoclax-based treatment. 2022.11; 97 (11): 1443-1452. ( PubMed , DOI )
Del5q with One Additional Cytogenetic Abnormality Other Than Del20q Identifies a Higher Risk Population of MDS Patients 2022.11; 140 4042-4044. ( DOI )
Ohara M, Sanjo N, Kanouchi T, Yokota T: Entrapment partly participates in the longitudinal progression of neuropathy with anti-MAG antibodies. Revue neurologique. 2022.11; 179 (1-2): 118-122. ( PubMed , DOI )
Outcome of Third-Line Tyrosine Kinase Inhibitors in Patients with Chronic Myeloid Leukemia in Chronic Phase: A Propensity Score Analysis 2022.11; 140 ( DOI )
Preclinical Efficacy of Novel Drug Combination Against AML with 3q26 Lesions and EVI1 Overexpression 2022.11; 140 ( DOI )
Updated Results from a Phase I/II Study of the Triplet Combination of Azacitidine, Venetoclax and Gilteritinib for Patients with FLT3-Mutated Acute Myeloid Leukemia 2022.11; 140 2007-2009. ( DOI )
Updated Phase IIb Results of Venetoclax with FLAG-IDA in Relapsed or Refractory Acute Myeloid Leukemia 2022.11; 140 ( DOI )
Updated Results of CPX-351 in Combination with Gemtuzumab Ozogamicin (GO) in Relapsed Refractory (R/R) Acute Myeloid Leukemia (AML) and Post-Hypomethylating Agent (Post-HMA) Failure High-Risk Myelodysplastic Syndrome (HR-MDS) 2022.11; 140 9050-9053. ( DOI )
Venetoclax Added to Cladribine (CLAD) plus Low Dose AraC (LDAC) Alternating with Azacitidine (AZA) Is Highly Active As Frontline Therapy in Older Patients with Newly Diagnosed Acute Myeloid Leukemia in a Phase 2 Study 2022.11; 140 9041-9043. ( DOI )
Efficacy of Novel Non-Chemotherapy Combinations Against AML Cells with Mutant NPM1 2022.11; 140 5860-5861. ( DOI )
Efficacy of Vcp/p97 Inhibitor, CB-5339, Alone and in Combinations Against High-Risk AML, Including Those with Genetic Lesion in TP53 2022.11; 140 8807-8808. ( DOI )
Frontline Combination of Hyper-CVAD with Ponatinib for Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia-6-Year Follow-up Results 2022.11; 140 3250-3252. ( DOI )
Homologous Recombination DNA Repair Deficiency Score Is Independent Prognostic Variable in Myelodysplastic Syndrome/ Acute Myeloid Leukemia with Complex Karyotype 2022.11; 140 1353-1354. ( DOI )
Splicing Gene Mutations Do Not Affect Outcomes in Newly Diagnosed Patients with Acute Myeloid Leukemia 2022.11; 140 1427-1429. ( DOI )
Clinical and Molecular Characterization of Newly Diagnosed IDH/TP53 Co-Mutated AML and Impact of Genomically Sensitive Treatment Strategies 2022.11; 140 6328-6330. ( DOI )
The Addition of Inotuzumab Ozogamicin to Hyper-CVAD Plus Blinatumomab Further Improves Outcomes in Patients with Newly Diagnosed B-Cell Acute Lymphoblastic Leukemia: Updated Results from a Phase II Study 2022.11; 140 8966-8968. ( DOI )
Transcriptomic Signatures of Hypomethylating Agent Failure in Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia. 2022.11; 115 44-53. ( PubMed , DOI )
A Phase II Study of Azacitidine and Venetoclax as Maintenance Therapy in Patients With Acute Myeloid Leukemia 2022.10; 22 S239-S240. ( DOI )
Acute Lymphoblastic Leukemia Following Multiple Myeloma Therapy: A Single-Center Experience With 9 Patients 2022.10; 22 S201-S202. ( DOI )
Asciminib Provides Durable Molecular Responses in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP) With the T315I Mutation: Updated Efficacy and Safety Data From a Phase I Trial 2022.10; 22 S300. ( DOI )
Association Between Myeloid Malignancies With MECOM Rearrangement and Ocular Adnexal Leukemic Infiltration 2022.10; 22 S233-S234. ( PubMed , DOI )
Prognostic Implication of the Molecular Profiles of Patients With Hypocellular Myelodysplastic Syndrome 2022.10; 22 S310. ( DOI )
Impact of ASXL1 Mutations on Prognosis of Chronic Phase Chronic Myeloid Leukemia 2022.10; 22 S291. ( DOI )
Updated Results from the Phase II Study of Blinatumomab in Combination With Ponatinib in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia 2022.10; 22 S204. ( DOI )
Prognostic impact of ASXL1 mutations in chronic phase chronic myeloid leukemia. 2022.10; 12 (10): 144. ( PubMed , DOI )
Efficacy and Safety Results From ASCEMBL, a Phase III Study of Asciminib vs. Bosutinib in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP) After.2 Prior Tyrosine Kinase Inhibitors (TKIs): Week 96 Update 2022.10; 22 S295-S296. ( DOI )
Yoshifuji Kota, Sasaki Koji: Adverse events and dose modifications of tyrosine kinase inhibitors in chronic myelogenous leukemia FRONTIERS IN ONCOLOGY. 2022.10; 12 1021662. ( PubMed , DOI )
The Role of FLT3 Inhibitors in Patients With Acute Myeloid Leukemia (AML) and T(6;9)(P22;Q34) 2022.10; 22 S258. ( DOI )
Low-dose decitabine versus low-dose azacitidine in lower-risk MDS 2022.09; 1 (10): ( DOI )
A multi-arm phase Ib/II study designed for rapid, parallel evaluation of novel immunotherapy combinations in relapsed/refractory acute myeloid leukemia. 2022.09; 63 (9): 2161-2170. ( PubMed , DOI )
Takahiro Mitsumura, Tsukasa Okamoto, Mizuho Tosaka, Takashi Yamana, Sho Shimada, Yuki Iijima, Rie Sakakibara, Sho Shibata, Takayuki Honda, Tsuyoshi Shirai, Masahiro Ishizuka, Junichi Aiboshi, Haruhiko Furusawa, Tomoya Tateishi, Meiyo Tamaoka, Hidenobu Shigemitsu, Hirokuni Arai, Yasuhiro Otomo, Shuji Tohda, Tatsuhiko Anzai, Kunihiko Takahashi, Shinsuke Yasuda, Yasunari Miyazaki: Association of SARS-CoV-2 RNA Copy Number with the COVID-19 Mortality Rate and Its Effect on the Predictive Performance of Mortality in Severe Cases. Jpn J Infect Dis. 2022.09; 75 (5): 504-510. ( PubMed , DOI )
Immunohistochemical loss of enhancer of Zeste Homolog 2 (EZH2) protein expression correlates with EZH2 alterations and portends a worse outcome in myelodysplastic syndromes. 2022.09; 35 (9): 1212-1219. ( PubMed , DOI )
High-resolution structural variant profiling of myelodysplastic syndromes by optical genome mapping uncovers cryptic aberrations of prognostic and therapeutic significance 2022.09; 36 (9): 2306-2316. ( PubMed , DOI )
Nogami A., Sasaki K.: Therapeutic Advances in Immunotherapies for Hematological Malignancies Therapeutic Advances in Immunotherapies for Hematological Malignancies. International Journal of Molecular Sciences . 2022.09; 23 11526.
Mitsumura Takahiro, Okamoto Tsukasa, Tosaka Mizuho, Yamana Takashi, Shimada Sho, Iijima Yuki, Sakakibara Rie, Shibata Sho, Honda Takayuki, Shirai Tsuyoshi, Ishizuka Masahiro, Aiboshi Junichi, Furusawa Haruhiko, Tateishi Tomoya, Tamaoka Meiyo, Shigemitsu Hidenobu, Arai Hirokuni, Otomo Yasuhiro, Tohda Shuji, Anzai Tatsuhiko, Takahashi Kunihiko, Yasuda Shinsuke, Miyazaki Yasunari: Association of SARS-CoV-2 RNA Copy Number with the COVID-19 Mortality Rate and Its Effect on the Predictive Performance of Mortality in Severe Cases(タイトル和訳中) Japanese Journal of Infectious Diseases. 2022.09; 75 (5): 504-510. ( ichushi )
Real‐life incidence of thrombotic events in leukemia patients treated with ponatinib 2022.09; 97 (9): E350-E352-E352. ( PubMed , DOI )
Transcatheter arterial embolization for hemothorax caused by spinal fracture without arterial injury: a case report and review of the literature. 2022.09; 16 (1): 332. ( PubMed , DOI )
Therapeutic Advances in Immunotherapies for Hematological Malignancies. 2022.09; 23 (19): ( PubMed , DOI )
Low‐dose dasatinib 50 mg/day versus standard‐dose dasatinib 100 mg/day as frontline therapy in chronic myeloid leukemia in chronic phase: A propensity score analysis 2022.08; 97 (11): 1413-1418. ( PubMed , DOI )
Venetoclax combined with FLAG-IDA induction and consolidation in newly diagnosed acute myeloid leukemia. 2022.08; 97 (8): 1035-1043. ( PubMed , DOI )
Yusuke Ota, Chihiro Tani Sassa, Masayo Kashiwagi, Chikako Okawara, Shuji Tohda, Ryoichi Saito: Complete Genome Sequence of an Enterobacter roggenkampii Strain with Reduced Carbapenem Susceptibility Isolated from a Home-Visit Nursing Agency. Microbiol Resour Announc. 2022.08; e0035322. ( PubMed , DOI )
TP53 ‐altered chronic lymphocytic leukemia treated with firstline Bruton's tyrosine kinase inhibitor‐based therapy: A retrospective analysis 2022.08; 97 (8): 1005-1012. ( PubMed , DOI )
Yuasa S, Nakajima J, Takatsuki Y, Takahashi Y, Tani-Sassa C, Iwasaki Y, Nagano K, Sonobe K, Yoshimoto T, Nukui Y, Takeuchi H, Tanimoto K, Tanaka Y, Kimura A, Ichimura N, Tohda S.: Viral load of SARS-CoV-2 Omicron is not high despite its high infectivity Journal of Medical Virology. 2022.07; 94 (11): 5543-5546. ( PubMed , DOI )
Urgent cytoreduction for newly diagnosed acute myeloid leukemia patients allows acquisition of pretreatment genomic data and enrollment on investigational clinical trials. 2022.07; 97 (7): 885-894. ( PubMed , DOI )
Prediction of survival with intensive chemotherapy in acute myeloid leukemia 2022.07; 97 (7): 865-876. ( PubMed , DOI )
Outcomes of patients with newly diagnosed acute myeloid leukemia (AML) and hyperleukocytosis. 2022.06; 40 (16): E19029. ( DOI )
Intrathecal prophylaxis with 12 versus 8 administrations reduces the incidence of central nervous system relapse in patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukemia 2022.06; 98 (1): E11-E14-E14. ( PubMed , DOI )
Phase 2 study of azacitidine (AZA) and venetoclax (VEN) as maintenance therapy for acute myeloid leukemia (AML) patients in remission. 2022.06; 40 (16): E19018.
A dynamic 3-factor survival model for acute myeloid leukemia that accounts for response to induction chemotherapy 2022.06; 97 (9): 1127-1134. ( PubMed , DOI )
A phase II trial of a chemotherapy-free combination of ponatinib and blinatumomab in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph plus ALL). 2022.06; 40 (16):
A phase II study of hyper-CVAD with sequential blinatumomab (Blina), with or without inotuzumab ozogamicin (INO), in adults with newly diagnosed B-cell acute lymphoblastic leukemia (ALL). 2022.06; 40 (16):
Acute myeloid leukemia with KMT2Ar and association with risk of bleeding and early mortality. 2022.06; 40 (16):
Hamada Satomi, Sasaki Kanae, Kito Hotaka, Tooyama Yui, Ihara Kensuke, Aoyagi Eiko, Ichimura Naoya, Tohda Shuji, Sasano Tetsuo: Effect of the recording condition on the quality of a single-lead electrocardiogram(和訳中) Heart and Vessels. 2022.06; 37 (6): 1010-1026. ( ichushi )
Treatment-free remission (TFR) in patients with chronic myeloid leukemia (CML) following the discontinuation of tyrosine kinase inhibitors. 2022.06; 40 (16):
Phase II Study of Venetoclax Added to Cladribine Plus Low-Dose Cytarabine Alternating With 5-Azacitidine in Older Patients With Newly Diagnosed Acute Myeloid Leukemia 2022.06; 374 (33): 3848-3857. ( PubMed , DOI )
Blinatumomab Is Associated with Favorable Outcomes in Patients With B-cell Lineage Acute Lymphoblastic Leukemia and Positive Measurable Residual Disease at a Threshold of 10-4 and Higher. 2022.06; 97 (9): 1135-1141. ( PubMed , DOI )
Efficacy and safety results from ASCEMBL, a phase 3 study of asciminib versus bosutinib (BOS) in patients (pts) with chronic myeloid leukemia in chronic phase (CML-CP) after >= 2 prior tyrosine kinase inhibitors (TKIs): Week 96 update. 2022.06; 40 (16):
Ryo Iwase, Tadashi Kanouchi, Toshitaka Yoshii, Taro Ishiguro, Takashi Hirai, Atsushi Okawa, Takanori Yokota, Nobuo Sanjo: Diverging pathophysiology in superficial siderosis with proximal upper limb amyotrophy. J Neurol Sci. 2022.05; 436 120248. ( PubMed , DOI )
Hypomethylating agent and venetoclax with FLT3 inhibitor "triplet" therapy in older/unfit patients with FLT3 mutated AML. 2022.05; 12 (5): 77. ( PubMed , DOI )
Venetoclax combined with induction chemotherapy in patients with newly diagnosed acute myeloid leukaemia: a post-hoc, propensity score-matched, cohort study. 2022.05; 9 (5): e350-e360-e360. ( PubMed , DOI )
Chromosomal Instability in Chronic Myeloid Leukemia: Mechanistic Insights and Effects. 2022.05; 14 (10): ( PubMed , DOI )
Improved survival of patients with myelofibrosis in the last decade: Single‐center experience 2022.04; 128 (8): 1658-1665. ( PubMed , DOI )
Intracranial hypertension associated with BCR-ABL1 tyrosine kinase inhibitors in chronic myeloid leukemia 2022.04; 63 (7): 1-4. ( PubMed , DOI )
Saito Tatsuya, Itoh M. A. I., Tohda Shuji: TYRO3 Knockdown Suppresses the Growth of Myeloid Leukaemia Cells ANTICANCER RESEARCH. 2022.04; 42 (4): 1757-1761. ( PubMed , DOI )
Satoru Aoyama, Shunichiro Yasuda, Huixin Li, Daisuke Watanabe, Yoshihiro Umezawa, Keigo Okada, Ayako Nogami, Osamu Miura, Norihiko Kawamata: A novel chimeric antigen receptor (CAR) system using an exogenous protease, in which activation of T cells is controlled by expression patterns of cell‑surface proteins on target cells. International Journal of Molecular Medicine. 2022.04; 49 (4): ( PubMed , DOI )
Tani-Sassa C, Iwasaki Y, Ichimura N, Nagano K, Takatsuki Y, Yuasa S, Takahashi Y, Nakajima J, Sonobe K, Nukui Y, Takeuchi H, Tanimoto K, Tanaka Y, Kimura A, Tohda S.: Viral loads and profile of the patients infected with SARS-CoV-2 Delta, Alpha, or R.1 variants in Tokyo Journal of Medical Virology. 2022.04; 94 (4): 1707-1710. ( PubMed , DOI )
Ryoichi Saito, Jun Nakajima, Isaac Prah, Masatomo Morita, Samiratu Mahazu, Yusuke Ota, Ayuka Kobayashi, Shuji Tohda, Hajime Kamiya, Hideyuki Takahashi, Makoto Ohnishi: Penicillin- and Ciprofloxacin-Resistant Invasive Neisseria meningitidis Isolates from Japan. Microbiol Spectr. 2022.04; e0062722. ( PubMed , DOI )
Improved outcomes among newly diagnosed patients with FMS‐like tyrosine kinase 3 internal tandem duplication mutated acute myeloid leukemia treated with contemporary therapy: Revisiting the European LeukemiaNet adverse risk classification 2022.03; 97 (3): 329-337. ( PubMed , DOI )
Major and minor complications of the pancreas after transcatheter arterial embolization using n-butyl-2-cyanoacrylate for acute bleeding from pancreatic arteries. 2022.03; 40 (3): 308-317. ( PubMed , DOI )
Dismal outcomes of patients with relapsed/refractory Philadelphia chromosome‐negative B‐cell acute lymphoblastic leukemia after failure of both inotuzumab ozogamicin and blinatumomab 2022.03; 97 (6): E201-E204-E204. ( PubMed , DOI )
Treatment‐Free Remission in Patients with Chronic Myeloid Leukemia Following the Discontinuation of Tyrosine Kinase Inhibitors 2022.03; 97 (7): 856-864. ( PubMed , DOI )
Genetic correlates in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with Hyper-CVAD plus dasatinib or ponatinib 2022.02; 36 (5): 1253-1260. ( PubMed , DOI )
Kawahara Tomoki, Ueki Yutaka, Nawa Nobutoshi, Miyamae Shigeru, Hanafusa Mariko, Goto Yuki, Tohda Shuji, Fujiwara Takeo: Characteristics of SARS-CoV-2 super-spreaders in Japan JOURNAL OF INFECTION. 2022.02; 84 (2): e6-e9. ( PubMed , DOI )
Kameda Takahiro, Horiuchi Yuna, Shimano Shitsuko, Yano Kouji, Lai Shao-Jui, Ichimura Naoya, Tohda Shuji, Kurihara Yuriko, Tozuka Minoru, Ohkawa Ryunosuke: Effect of myeloperoxidase oxidation and N-homocysteinylation of high-density lipoprotein on endothelial repair function BIOLOGICAL CHEMISTRY. 2022.02; 403 (3): 265-277. ( PubMed , DOI )
Yamada Toru, Suzuki Risa, Ichimura Naoya, Mabuchi Suguru, Nagamine Yuiko, Sassa Chihiro, Tohda Shuji: Clinical Evaluation of Reverse Transcription-Polymerase Chain Reaction and Rapid Antigen Tests of Tongue Swabs for Detecting COVID-19(和訳中) Journal of Hospital General Medicine. 2022.01; 4 (1): 12-20. ( ichushi )
Prediction of early (4‐week) mortality in acute myeloid leukemia with intensive chemotherapy 2022.01; 97 (1): 68-78. ( PubMed , DOI )
Characteristics and Outcomes of Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm Treated with Frontline HCVAD 2022.01; 6 (10): 3027-3035. ( PubMed , DOI )
Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c) 2022.01; 12 (1): 5. ( PubMed , DOI )
Yusuke Ota, Natsune Hongou, Yoko Nukui, Ryuji Koike, Shuji Tohda, Ryoichi Saito: Evaluation of polymerase chain reaction-based open reading frame typing method for the clonality investigation of Clostridioides difficile isolates. Anaerobe. 2021.12; 72 102462. ( PubMed , DOI )
Ibrutinib, fludarabine, cyclophosphamide, and obinutuzumab (iFCG) regimen for chronic lymphocytic leukemia (CLL) with mutated IGHV and without TP53 aberrations. 2021.12; 35 (12): 3421-3429. ( PubMed , DOI )
Prediction for sustained deep molecular response for treatment-free remission. 2021.12; 63 (1): 5-6. ( PubMed , DOI )
Efficacy of superselective transcatheter arterial embolization for intractable postpartum hemorrhage due to genital tract trauma after vaginal delivery. 2021.12; 28 (6): 1127-1133. ( PubMed , DOI )
Outcomes of Patients with Chronic Myelomonocytic Leukemia (CMML) Treated with Hypomethylating Agents 2021.11; 138 ( DOI )
Efficacy and Safety Results from Ascembl, a Multicenter, Open-Label, Phase 3 Study of Asciminib, a First -in -Class STAMP Inhibitor, Vs Bosutinib in Patients with Chronic Myeloid Leukemia in Chronic Phase after >= 2 Prior Tyrosine Kinase Inhibitors: Update after 48 Weeks 2021.11; 138 ( DOI )
Phase I/II Study of Azacitidine (AZA) with Venetoclax (VEN) and Magrolimab (Magro) in Patients (pts) with Newly Diagnosed Older/Unfit or High-Risk Acute Myeloid Leukemia (AML) and Relapsed/Refractory (R/R) AML 2021.11; 138 ( DOI )
Liposomal Cytarabine and Daunorubicin (CPX-351) in Combination with Gemtuzumab Ozogamicin (GO) in Relapsed Refractory (R/R) Acute Myeloid Leukemia (AML) and PostHypomethylating Agent (Post-HMA) Failure High-Risk Myelodysplastic Syndrome (HR-MDS) 2021.11; 138 ( DOI )
Long-Term Follow-up of the Combination of Low-Intensity Chemotherapy Plus Inotuzumab Ozogamicin with or without Blinatumomab in Patients with Relapsed-Refractory Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia 2021.11; 138 ( DOI )
A Phase II Study of 5-Azacytidine (AZA) and Venetoclax As Maintenance Therapy in Patients with Acute Myeloid Leukemia (AML) in Remission 2021.11; 138 ( DOI )
A Phase II Study of Inotuzumab Ozogamicin for the Treatment of Measurable Residual Disease-Positive BCell Acute Lymphoblastic Leukemia 2021.11; 138 ( DOI )
A Triplet Combination of Azacitidine, Venetoclax and Gilteritinib for Patients with FLT3-Mutated Acute Myeloid Leukemia: Results from a Phase I/II Study 2021.11; 138 ( DOI )
NPM1 Mutations Do Not Retain a Favorable Prognostic Impact in Adults with Advanced Relapsed or Refractory (R/R) Acute Myeloid Leukemia (AML) 2021.11; 138 ( DOI )
Association between Bariatric Surgery and Outcomes in Patients with Chronic Myeloid Leukemia Treated with Oral Tyrosine Kinase Inhibitors 2021.11; 138 ( DOI )
Disease Characteristics of Multiple Myeloma Involving BRAF Mutations 2021.11; 138 ( DOI )
Outcomes for Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Treated with Frontline HCVADBased Chemotherapy 2021.11; 138 ( DOI )
Azacitidine, Venetoclax and Pevonedistat As Frontline Therapy for Patients with Secondary Acute Myeloid Leukemia Who Are Unfit for Intensive Chemotherapy: Results from a Phase I/II Study 2021.11; 138 ( DOI )
Phase II Trial of Ten-Day Decitabine with Venetoclax (DEC10-VEN) in Acute Myeloid Leukemia: Updated Outcomes in Genomic Subgroups 2021.11; 138 ( DOI )
Updated Results of a Phase II Study of Ponatinib and Blinatumomab for Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia 2021.11; 138 ( DOI )
General Characteristics and Association of Myeloid Neoplasm with Thyroid Cancer 2021.11; 138 ( DOI )
Hypomethylating Agent (HMA) Therapy and Venetoclax (VEN) with FLT3 Inhibitor "Triplet" Therapy Is Highly Active in Older/Unfit Patients with FLT3 Mutated AML 2021.11; 138 ( DOI )
Retrospective Single-Institution Analysis of Patients with Chronic Lymphocytic Leukemia with TP53 alterations Treated First-Line with Bruton's Tyrosine Kinase Inhibitor-Based Therapy 2021.11; 138 ( DOI )
Clinical and Pathological Characteristics of Hypocellular Myelodysplastic Syndrome : A Single-Center Retrospective Study 2021.11; 138 ( DOI )
Clinical Outcomes of Patients with Newly Diagnosed Myelodysplastic Syndrome with MLL Aberrations 2021.11; 138 ( DOI )
The effect of eltrombopag in managing thrombocytopenia associated with tyrosine kinase therapy in patients with chronic myeloid leukemia and myelofibrosis. 2021.11; 106 (11): 2853-2858. ( PubMed , DOI )
Ten-Day Decitabine with Venetoclax (DEC10-VEN) in Acute Myeloid Leukemia and Myelodysplastic Syndrome: Updated Results of a Phase II Trial 2021.11; 138 ( DOI )
The Prognostic Implication of Adult Comorbidity Evaluation 27 Score in CML Patients on Tyrosine-Kinase Inhibitors 2021.11; 138 ( DOI )
Clonal dynamics and clinical implications of postremission clonal hematopoiesis in acute myeloid leukemia. 2021.11; 138 (18): 1733-1739. ( PubMed , DOI )
Transcriptomic Signitures of Azacitidine (AZA) and Decitabine (DAC) Resistance in MDS and CMML 2021.11; 138 ( DOI )
Phase II Study of Venetoclax Added to Cladribine (CLAD) and Low Dose AraC (LDAC) Alternating with 5-Azacytidine (AZA) in Older and Unfit Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) 2021.11; 138 ( DOI )
Only SF3B1 mutation involving K700E independently predicts overall survival in myelodysplastic syndromes. 2021.10; 127 (19): 3552-3565. ( PubMed , DOI )
Takayuki Kuroda, Miho Akaza, Kazunori Miki, Shoko Fujii, Yousuke Yagi, Tadashi Kanouchi, Nobuo Sanjo, Kazutaka Sumita, Takanori Yokota: Sacral dural arteriovenous fistula mimicking multiple mononeuropathy. Clin Neurol Neurosurg. 2021.10; 210 106993. ( PubMed , DOI )
Outcomes in patients with newly diagnosed TP53-mutated acute myeloid leukemia with or without venetoclax-based therapy. 2021.10; 127 (19): 3541-3551. ( PubMed , DOI )
Improved Survival of Patients with Primary Myelofibrosis in the Last Decade at a Large Single Academic Center 2021.09; 21 S361.
A Simplified Three-Marker Panel for Myelodysplastic Syndrome Prognostic Outperforms the Well-Established Revised International Prognostic Scoring Systems (IPSS-R) 2021.09; 21 S351.
Predictors of outcomes in adults with acute myeloid leukemia and KMT2A rearrangements. 2021.09; 11 (9): 162. ( PubMed , DOI )
Prognostic impact of conventional cytogenetics in acute myeloid leukemia treated with venetoclax and decitabine. 2021.09; 62 (14): 3501-3505. ( PubMed , DOI )
Venetoclax Combined With FLAG-IDA Induction and Consolidation in Newly Diagnosed and Relapsed or Refractory Acute Myeloid Leukemia. 2021.09; 39 (25): 2768-2778. ( PubMed , DOI )
Venetoclax Combined with FLAG-IDA Induction and Consolidation in Newly Diagnosed Acute Myeloid Leukemia 2021.09; 21 S291.
Hyper-CVAD plus ofatumumab versus hyper-CVAD plus rituximab as frontline therapy in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia: A propensity score analysis. 2021.09; 127 (18): 3381-3389. ( PubMed , DOI )
Clinicopathologic correlates and natural history of atypical chronic myeloid leukemia. 2021.09; 127 (17): 3113-3124. ( PubMed , DOI )
A Phase 3, Open-Label, Randomized Study of Asciminib, a STAMP Inhibitor, vs Bosutinib in CML After ≥2 Prior TKIs. 2021.08; 138 (21): 2031-2041. ( PubMed , DOI )
Ibrutinib plus Venetoclax for First-line Treatment of Chronic Lymphocytic Leukemia: A Nonrandomized Phase 2 Trial 2021.08; 7 (8): 1213-1219. ( PubMed , DOI )
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Sasaki, K; Jabbour, E; Issa, GC; Garcia-Manero, G; Kadia, TM; Wierda, WG; Yilmaz, M; DiNardo, CD; Skinner, J; Khouri, M; Pemmaraju, N; Nasnas, P; Pierce, SA; Cortes, JE; Kantarjian, HM: Outcomes of Patients with Chronic Myeloid Leukemia Treated with Third-Line Tyrosine Kinase Inhibitors BLOOD. 2020.11; 136 ( DOI )
Interim Results of an Open-Label Phase IB/II Multi-Arm Study of OX40 Agonist Monoclonal Antibody (mAb), Anti-PDL1 Mab, Smoothened Inhibitor, Anti-CD33 Mab, Bcl-2 Inhibitor, and Azacitidine As Single-Agents and As Combinations for Relapsed/Refractory Acute Myeloid Leukemia 2020.11; 136 ( DOI )
Interim Analysis of the Phase 1b/2 Study of the BCL-2 Inhibitor Venetoclax in Combination with Standard Intensive AML Induction/Consolidation Therapy with FLAG-IDA in Patients with Newly Diagnosed or Relapsed/Refractory AML 2020.11; 136 ( DOI )
Morita, K; Bravo, GM; Sasaki, K; Bodden, KR; Wang, F; Bose, P; Alvarado, Y; Daver, N; Borthakur, G; Ravandi, F; Takahashi, K; Jabbour, E; DiNardo, CD; Pemmaraju, N; Kadia, TM; Ohanian, M; Pierce, SA; Azab, M; Kantarjian, HM; Garcia-Manero, G: Long-Term Follow up of a Phase II Study of Guadecitabine (SGI-110) in Patients with Higher-Risk Myelodysplastic Syndrome (MDS) BLOOD. 2020.11; 136 ( DOI )
Perez, JMR; Kadia, TM; Montalban-Bravo, G; Faderl, S; Sasaki, K; Daver, N; DiNardo, CD; Masarova, L; Ferrajoli, A; Jabbour, E; Borthakur, G; Al Azzawi, H; Pemmaraju, N; Konopleva, M; Pierce, SA; Garcia-Manero, G; Andreeff, M; Kantarjian, HM; Ravandi, F; Alvarado, Y: Liposomal Cytarabine and Daunorubicin (CPX-351) in Combination with Gemtuzumab Ozogamicin (GO) in Relapsed Refractory (R/R) Patients with Acute Myeloid Leukemia (AML) and Post-Hypomethylating Agent (Post-HMA) Failure High-Risk Myelodysplastic Syndrome (HR-MDS) BLOOD. 2020.11; 136 ( DOI )
Sasaki, K; Jabbour, E; Bravo, GM; Short, NJ; Kanagal-Shamanna, R; Kadia, TM; Borthakur, G; Pemmaraju, N; Cortes, JE; Ravandi, F; Alvarado, Y; Chien, KS; Yang, H; Kantarjian, HM; Garcia-Manero, G: Long-Term Outcome of Low-Dose Hypomethylating Agents in Lower-Risk Myelodysplastic Syndromes: A Randomized Phase 2 Study BLOOD. 2020.11; 136 ( DOI )
Sasaki, K; Kantarjian, HM; Ravandi, F; Short, NJ; Kebriaei, P; Huang, XL; Jain, N; Konopleva, M; Garcia-Manero, G; Champlin, RE; Kadia, TM; Takahashi, K; Daver, N; Rafei, H; Khoury, JD; Jorgensen, JL; Wang, SA; Khouri, MR: Long-Term Follow-up of the Combination of Low-Intensity Chemotherapy Plus Inotuzumab Ozogamicin with or without Blinatumomab in Patients with Relapsed-Refractory Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia: A Phase 2 Trial BLOOD. 2020.11; 136 ( DOI )
Morita, K; Kantarjian, HM; Bravo, GM; Sasaki, K; Daver, N; Jabbour, E; Alvarado, Y; Chien, KS; DiNardo, CD; Ravandi, F; Borthakur, G; Bose, P; Pemmaraju, N; Naqvi, K; Cortes, JE; Kadia, TM; Konopleva, M; Rausch, CR; Gasior, Y; Garcia-Manero, G: A Phase II Study of Double Immune Checkpoint Inhibitor Blockade with Nivolumab and Ipilimumab with or without Azacitidine in Patients with Myelodysplastic Syndrome (MDS) BLOOD. 2020.11; 136 ( DOI )
A Prognostic Model for Survival in Patients with Relapsed/Refractory Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia on the Combination of Low-Intensity Chemotherapy Plus Inotuzumab Ozogamicin with or without Blinatumomab 2020.11; 136 ( DOI )
Kanagal-Shamanna, R; Bravo, GM; Sasaki, K; Bueso-Ramos, CE; Jabbour, E; Wei, Y; Darbaniyan, F; Routbort, M; Pierce, SA; Soltysiak, KA; Patel, K; Medeiros, LJ; Kantarjian, HM; Garcia-Manero, G: Only Hotspot SF3B1 K700E Mutation Is an Independent Predictor of Overall Survival in Myelodysplastic Syndromes BLOOD. 2020.11; 136 ( DOI )
Hammond, D; DiNardo, CD; Konopleva, M; Borthakur, G; Perez, JMR; Guerra, VA; Kanagal-Shamanna, R; Paul, S; Naqvi, K; Sasaki, K; Jabbour, E; Pemmaraju, N; Kadia, TM; Ravandi, F; Daver, N; Estrov, ZE; Pierce, SA; Kantarjian, HM; Garcia-Manero, G; Montalban-Bravo, G: Activity of Venetoclax-Based Therapy in CMML and CMML with Blast Transformation BLOOD. 2020.11; 136 ( DOI )
Azacitidine (AZA) with Nivolumab (Nivo), and AZA with Nivo plus Ipilimumab (Ipi) in Relapsed/Refractory (R/R) Acute Myeloid Leukemia: Clinical and Immune Biomarkers of Response 2020.11; 136 ( DOI )
Jain, N; Keating, MJ; Thompson, PA; Ferrajoli, A; Burger, JA; Borthakur, G; Takahashi, K; Estrov, ZE; Sasaki, K; Fowler, NH; Kadia, TM; Konopleva, M; Alvarado, Y; Yilmaz, M; DiNardo, CD; Bose, P; Ohanian, M; Pemmaraju, N; Jabbour, E; Kanagal-Shamanna, R; Patel, K; Wang, W; Jorgensen, JL; Wang, SA; Garg, N; Wang, XM; Cruz, N; Ayala, A; Plunkett, W; Kantarjian, HM; Gandhi, V; Wierda, WG: Combined Ibrutinib and Venetoclax for First-Line Treatment for Patients with Chronic Lymphocytic Leukemia (CLL): Focus on MRD Results BLOOD. 2020.11; 136 ( DOI )
Comparison of Hyper-CVAD Plus Ofatumumab to Hyper-CVAD Plus Rituximab in Patients with Newly Diagnosed Philadelphia Chromosome-Negative CD20-Positive B-Cell Acute Lymphoblastic Leukemia: A Propensity Score Analysis 2020.11; 136 ( DOI )
Outcome of Patients with T-Cell Acute Lymphoblastic Leukemia/Lymphoma with Early T-Cell Precursor-like Immunophenotype with Strong CD5 Expression 2020.11; 136 ( DOI )
Morita, K; Kantarjian, HM; Ravandi, F; Sasaki, K; Jain, N; Konopleva, M; Short, NJ; Takahashi, K; Khouri, R; Nasnas, P; DiNardo, CD; Kadia, TM; Garcia-Manero, G; Daver, N; Bravo, GM; Issa, GC; Cortes, JE; Jabbour, E: Outcome of Patients with Chronic Myeloid Leukemia in Lymphoid Blast Crisis (CML-LBC) and Philadelphia Chromosome (Ph)-Positive Acute Lymphoblastic Leukemia (ALL) Treated with Hyper-CVAD and Dasatinib BLOOD. 2020.11; 136 ( DOI )
Rafei, H; Kantarjian, HM; Sasaki, K; Short, NJ; Ravandi, F; Huang, XL; Khoury, JD; Wang, SA; Jorgensen, JL; Yin, CC; Khouri, IF; Kebriaei, P; Jain, N; Takahashi, K; Dabaja, BS; Verstovsek, S; Kadia, TM; Paul, S; Rausch, CR; Garcia-Manero, G; Wierda, WG; DiNardo, CD; Daver, N; Montalban-Bravo, G; Yilmaz, M; Nasnas, P; Khouri, R; Kwari, M; Jacob, J; Rostykus, M; Garris, R; Konopleva, M; O'Brien, SM; Jabbour, E: Impact of Cytogenetic Abnormalities (CA) on Outcome of Patients (Pts) with Relapsed/Refractory (R-R) Acute Lymphoblastic Leukemia (ALL) Treated with Inotuzumab Ozogamicin (INO) in Combination with Low-Intensity Chemotherapy (mini-hyper-CVD) with or without Blinatumomab: Results from a Phase 2 Study BLOOD. 2020.11; 136 ( DOI )
Sasaki, K; Kantarjian, HM; Issa, GC; Garcia-Manero, G; Kadia, TM; Wierda, WG; Yilmaz, M; DiNardo, CD; Skinner, J; Khouri, R; Pemmaraju, N; Nasnas, P; Dellasala, SE; Pierce, SA; Cortes, JE; Jabbour, E: Impact of Molecular Response at Specific Timepoints in Patients with Newly Diagnosed Chronic Myeloid Leukemia Treated with Second Generation Tyrosine Kinase Inhibitors BLOOD. 2020.11; 136 ( DOI )
Darbaniyan, F; Bravo, GM; Wei, Y; Kanagal-Shamanna, R; Sasaki, K; Yang, H; Soltysiak, KA; Chien, KS; Do, KA: Impact of Hemoglobin Level As a Continuous Variable in Calculating Prognosis in MDS: Incorporation into LSC4 and IPSS-R BLOOD. 2020.11; 136 ( DOI )
Reville, PK; González, GMN; Ravandi, F; Sasaki, K; Borthakur, G; Garcia-Manero, G; Daver, N; DiNardo, CD; Jabbour, E; Pemmaraju, N; Andreeff, M; Verstovsek, S; Ferrajoli, A; Jain, N; Ohanian, M; Pierce, SA; Estrov, ZE; Konopleva, M; Kantarjian, HM; Kadia, TM: Predictors of Early Mortality, Response, and Survival in Newly Diagnosed Acute Myeloid Leukemia (AML) Using a Contemporary Academic Cohort BLOOD. 2020.11; 136 ( DOI )
CD22 Expression Level As a Predictor of Survival in Patients (Pts) with Relapsed/Refractory (R-R) Acute Lymphoblastic Leukemia (ALL) Treated with Inotuzumab Ozogamicin (INO) in Combination with Low-Intensity Chemotherapy (mini-hyper-CVD) with or without Blinatumomab: Results from a Phase 2 Study 2020.11; 136 ( DOI )
Hochhaus, A; Boquimpani, C; Rea, D; Minami, Y; Lomaia, E; Voloshin, S; Turkina, AG; Kim, DW; Apperley, J; Cortes, JE; Abdo, A; Fogliatto, LM; Kim, DDH; Le Coutre, PD; Saussele, S; Annunziata, M; Hughes, TP; Chaudhri, NA; Chee, LCY; Gutierrez, VG; Sasaki, K; Aimone, P; Allepuz, A; Quenet, S; Bédoucha, V; Mauro, MJ: Efficacy and Safety Results from ASCEMBL, a Multicenter, Open-Label, Phase 3 Study of Asciminib, a First-in-Class STAMP Inhibitor, vs Bosutinib (BOS) in Patients (Pts) with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) Previously Treated with ≥2 Tyrosine Kinase Inhibitors (TKIs BLOOD. 2020.11; 136 ( DOI )
Kanagal-Shamanna, R; Bravo, GM; Katsonis, P; Sasaki, K; Class, C; Benton, CB; Jabbour, E; Chien, KS; Luthra, R; Bueso-Ramos, CE; Kadia, TM; Andreeff, M; Short, NJ; Daver, N; Routbort, M; Khoury, JD; Patel, K; Ganan-Gomez, I; Wei, Y; Borthakur, G; Ravandi, F; Do, KA; Soltysiak, KA; Lichtarge, O; Medeiros, LJ; Kantarjian, HM; Garcia-Manero, G: Evolutionary Action Score Identifies a Subset of TP53 Mutated Myelodysplastic Syndrome with Favorable Prognosis BLOOD. 2020.11; 136 ( DOI )
Cherng, HJJ; Jammal, N; Paul, S; Wang, XM; Sasaki, K; Thompson, PA; Burger, JA; Ferrajoli, A; Estrov, ZE; O'Brien, SM; Keating, MJ; Wierda, WG; Jain, N: Examination of Clinical and Molecular Characteristics and Treatment Patterns of Adolescent and Young Adult (AYA) Patients with Chronic Lymphocytic Leukemia BLOOD. 2020.11; 136 ( DOI )
Bravo, GM; Kanagal-Shamanna, R; Darbaniyan, F; Ganan-Gomez, I; Sasaki, K; Naqvi, K; Wei, Y; Yang, H; Soltysiak, KA; Chien, KS; Bueso-Ramos, CE; Kantarjian, HM; Garcia-Manero, G: Genomic and Transcriptomic Differences of Myelodysplastic Syndrome/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T) and Myelodysplastic Syndrome with Ring Sideroblasts (MDS-RS) BLOOD. 2020.11; 136 ( DOI )
Major, CK; Kantarjian, H; Sasaki, K; Borthakur, G; Kadia, T; Pemmaraju, N; DiNardo, C; Short, NJ; Daver, N; Jabbour, E; Champlin, R; Garcia-Manero, G; Konopleva, M; Andreeff, M; Kornblau, S; Wierda, W; Pierce, S; Ravandi, F; Cortes, J: Survivorship in AML - a landmark analysis on the outcomes of acute myelogenous leukemia patients after maintaining complete remission for at least 3 years LEUKEMIA & LYMPHOMA. 2020.11; 61 (13): 3120-3127. ( PubMed , DOI )
Maiti, A; DiNardo, CD; Wang, SA; Jorgensen, JL; Kadia, TM; Daver, N; Short, NJ; Yilmaz, M; Pemmaraju, N; Borthakur, G; Bose, P; Issa, GC; Ferrajoli, A; Jabbour, E; Jain, N; Garcia-Manero, G; Ohanian, M; Takahashi, K; Montalban-Bravo, G; Masarova, L; Burger, JA; Thompson, PA; Verstovsek, S; Sasaki, K; Andreeff, M; Rausch, CR; Montalbano, K; Pierce, SA; Kantarjian, HM; Konopleva, M; Ravandi, F: Prognostic Value of Measurable Residual Disease after Venetoclax and Decitabine in Acute Myeloid Leukemia BLOOD. 2020.11; 136 ( DOI )
Prognostic Significance of Genetic Alterations in Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Treated with Hyper-CVAD Plus Dasatinib or Hyper-CVAD Plus Ponatinib 2020.11; 136 ( DOI )
Guerra, VA; Alwash, Y; Yan, YQ; Perez, JMR; Richard-Carpentier, G; Alotaibi, AS; Ahaneku, HO; Samra, B; Raghunath, A; Jain, N; Short, NJ; Ravandi, F; Borthakur, G; Ferrajoli, A; Sasaki, K; Kornblau, SM; Estrov, ZE; Cortes, JE; Kantarjian, HM; Garcia-Manero, G; Jabbour, E; Kadia, TM: Risk Factors Associated with 30-Day Unplanned Readmissions for Adult Acute Lymphoblastic Leukemia (ALL) BLOOD. 2020.11; 136 ( DOI )
Perez, JMR; Guerra, VA; Hammond, D; Chien, KS; Kanagal-Shamanna, R; Naqvi, K; Sasaki, K; Paul, S; Kadia, TM; DiNardo, CD; Konopleva, M; Daver, N; Ravandi, F; Pemmaraju, N; Short, NJ; Takahashi, K; Estrov, ZE; Pierce, SA; Kantarjian, HM; Garcia-Manero, G; Montalban-Bravo, G: Response and Survival Outcomes with Hypomethylating Agents in Patients with Chronic Myelomonocytic Leukemia Based on Disease Phenotype and Risk Categories BLOOD. 2020.11; 136 ( DOI )
Rafei, H; Kantarjian, HM; Sasaki, K; Short, NJ; Ravandi, F; Huang, XL; Khoury, JD; Wang, SA; Jorgensen, JL; Khouri, IF; Kebriaei, P; Champlin, RE; Jain, N; Dabaja, BS; Issa, GC; Pemmaraju, N; Kadia, TM; Paul, S; Jammal, N; Garcia-Manero, G; Wierda, WG; DiNardo, CD; Daver, N; Montalban-Bravo, G; Khouri, R; Nasnas, P; Thompson, PA; Jacob, J; Rostykus, M; Garris, R; Konopleva, M; O'Brien, SM; Jabbour, E: Roleof Allogeneic Stem Cell Transplant (ASCT) in Patients (Pts) with Relapsed/Refractory (R-R) Acute Lymphoblastic Leukemia (ALL) Treated with Inotuzumab Ozogamicin (INO) in Combination with Low-Intensity Chemotherapy (mini-hyper-CVD) with or without Blinatumomab (Blina): Results from a Phase 2 Study BLOOD. 2020.11; 136 ( DOI )
Sequential Combination of Inotuzumab Ozogamicin (InO) with Low-Intensity Chemotherapy (mini-hyper-CVD) with or without Blinatumomab (Blina) As Salvage Therapy for Patients (Pts) with Acute Lymphoblastic Leukemia (ALL) in First Relapse 2020.11; 136 ( DOI )
Bravo, GM; Kanagal-Shamanna, R; Guerra, V; Perez, JMR; Hammond, D; Paul, S; Naqvi, K; Sasaki, K; Jabbour, E; DiNardo, CD; Takahashi, K; Konopleva, M; Pemmaraju, N; Kadia, TM; Ravandi, F; Daver, N; Borthakur, G; Estrov, ZE; Khoury, JD; Loghavi, S; Pierce, SA; Bueso-Ramos, CE; Patel, K; Kantarjian, HM: Clinical Outcomes and Influence of Mutation Clonal Dominance in Oligomonocytic and Classical Chronic Myelomonocytic Leukemia BLOOD. 2020.11; 136 ( DOI )
Bravo, GM; Kanagal-Shamanna, R; Sasaki, K; Masarova, L; Naqvi, K; Jabbour, E; DiNardo, CD; Takahashi, K; Konopleva, M; Pemmaraju, N; Short, NJ; Issa, GC; Kadia, TM; Ravandi, F; Daver, N; Borthakur, G; Estrov, ZE; Khoury, JD; Loghavi, S; Pierce, SA; Bueso-Ramos, CE; Patel, K; Verstovsek, S; Kantarjian, HM; Bose, P; Garcia-Manero, G: Clinicopathologic Correlates and Natural History of Atypical Chronic Myeloid Leukemia BLOOD. 2020.11; 136 ( DOI )
Sasaki, K; Jabbour, E; Naqvi, K; Skinner, J; Anderson, K; Dellasala, SE; Yilmaz, M; Ferrajoli, A; Bose, P; Thompson, PA; Alvarado, Y; Jain, N; Garcia-Manero, G; Takahashi, K; Burger, JA; Borthakur, G; Pemmaraju, N; Khouri, R; Paul, S; Pierce, SA; Cortes, JE; Kantarjian, HM: The Comparison of Frontline Lower-Dose Dasatinib 50 Mg/Day to Standard-Dose Dasatinib 100 Mg/Day in Newly Diagnosed Chronic Myeloid Leukemia: A Propensity Score Analysis BLOOD. 2020.11; 136 ( DOI )
Siddiqui, MT; Kanagal-Shamanna, R; Naqvi, K; Sasaki, K; Masarova, L; Jabbour, E; Pemmaraju, N; Kadia, TM; Ravandi, F; Daver, N; Borthakur, G; Pierce, SA; Verstovsek, S; Bose, P; Kantarjian, HM; Garcia-Manero, G; Montalban-Bravo, G: Clinical Outcomes with Hypomethylating Agents in Patients with Myelodysplastic Syndrome/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T); A Case Series BLOOD. 2020.11; 136 ( DOI )
Phase II Study of Venetoclax Added to Cladribine plus Low Dose AraC (LDAC) Alternating with 5-Azacytidine Demonstrates High Rates of Minimal Residual Disease (MRD) Negative Complete Remissions (CR) and Excellent Tolerability in Older Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) 2020.11; 136 ( DOI )
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Issa, G; Zarka, J; Sasaki, K; Short, N; Jabbour, E; Kadia, T; Borthakur, G; Garcia-Manero, G; Kantarjian, H; Ravandi, F: Predictors of Outcomes in AML with MLL Rearrangement CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2020.09; 20 S202-S203.
Jabbour, E; Richard-Carpentier, G; Sasaki, Y; Konopleva, M; Patel, K; Roberts, K; Gu, ZH; Wang, F; Huang, XL; Sasaki, K; Short, NJ; Jain, N; Ravandi, F; Daver, NG; Kadia, TM; Alvarado, Y; DiNardo, CD; Issa, GC; Pemmaraju, N; Garcia-Manero, G; Verstovsek, S; Wang, S; Khoury, JD; Jorgensen, J; Champlin, R; Khouri, I; Kebriaei, P; Schroeder, H; Khouri, M; Mullighan, CG; Takahashi, K; O'Brien, SM; Kantarjian, H: Hyper-CVAD regimen in combination with ofatumumab as frontline therapy for adults with Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia: a single-arm, phase 2 trial LANCET HAEMATOLOGY. 2020.07; 7 (7): E523-E533. ( PubMed , DOI )
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Tatsuya Saito, Mai Itoh, Shuji Tohda: Metformin suppresses the growth of leukemia cells partly through downregulation of AXL receptor tyrosine kinase. Leuk Res. 2020.05; 94 106383. ( PubMed , DOI )
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Yukino Usui, Alafate Ayibieke, Yuko Kamiichi, Shu Okugawa, Kyoji Moriya, Shuji Tohda, Ryoichi Saito: Impact of deoxycholate on Clostridioides difficile growth, toxin production, and sporulation. Heliyon. 2020.04; 6 (4): e03717. ( PubMed , DOI )
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Watanabe D, Nogami A, Okada K, Akiyama H, Umezawa Y, Miura O: FLT3-ITD Activates RSK1 to Enhance Proliferation and Survival of AML Cells by Activating mTORC1 and eIF4B Cooperatively with PIM or PI3K and by Inhibiting Bad and BIM. Cancers. 2019.11; 11 (12): ( PubMed , DOI )
Yagi Yohsuke, Iida Shintaro, Kanouchi Tadashi, Kusunoki Susumu, Sobue Gen, Kaji Ryuji, Kuwabara Satoshi, Yokota Takanori, Glovenin-I CIDP Study Group: IVIg維持療法はCIDPの進行を抑制する(Maintenance treatment with IVIg for CIDP can prevent disease progression) 臨床神経学. 2019.11; 59 (Suppl.): S384. ( ichushi )
Short, NJ; Kantarjian, HM; Kanagal-Shamanna, R; Sasaki, K; Ravandi, F; Cortes, JE; Konopleva, MY; Issa, GC; Kornblau, SM; Garcia-Manero, G; Rivera, V; Garris, R; Higgins, J; Pratt, G; Williams, LN; Valentine, CC; Salk, JJ; Prichard, J; Radich, JP; Jabbour, E: Ultra-Accurate Assessment of Pretreatment ABL1 Kinase Domain (KD) Mutations in Patients (pts) with Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph plus ALL) Using Duplex Sequencing (DS) BLOOD. 2019.11; 134 ( DOI )
Montalban-Bravo, G; Class, C; Ganan-Gomez, I; Kanagal-Shamanna, R; Sasaki, K; Richard-Carpentier, G; Naqvi, K; Wei, Y; Yang, H; Soltysiak, K; Chien, KS; Bueso-Ramos, CE; Do, KA; Kantarjian, HM; Garcia-Manero, G: Transcriptomic Analysis Implicates Necroptosis in Disease Progression and Prognosis in Myelodysplastic Syndromes BLOOD. 2019.11; 134 ( DOI )
Short, NJ; Kantarjian, HM; Ravandi, F; Huang, XL; Jain, N; Sasaki, K; Khouri, R; Daver, NG; Pemmaraju, N; Khoury, JD; Jorgensen, JL; Alvarado, Y; Konopleva, MY; Garcia-Manero, G; Kadia, TM; Yilmaz, ME; Borthakur, GM; Burger, JA; Kornblau, SM; Wierda, WG; DiNardo, CD; Ferrajoli, A; Jacob, J; Rostykus, M; Garris, R; Ward, M; Huang, BR; Encarnacion, C; Loiselle, C; O'Brien, SM; Jabbour, E: Updated Results of a Phase II Study of Reduced-Intensity Chemotherapy with Mini-Hyper-CVD in Combination with Inotuzumab Ozogamicin, with or without Blinatumomab, in Older Adults with Newly Diagnosed Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia BLOOD. 2019.11; 134 ( DOI )
Richard-Carpentier, G; Kantarjian, HM; Short, NJ; Ravandi, F; Ferrajoli, A; Schroeder, HM; Garcia-Manero, G; Bravo, GM; Cortes, JE; Kwari, M; Loiselle, C; Garris, R; Volter, N; Jain, N; Konopleva, MY; Takahashi, K; Sasaki, K; Wierda, WG; Jabbour, E: Updated Results from the Phase II Study of Hyper-CVAD in Sequential Combination with Blinatumomab in Newly Diagnosed Adults with B-Cell Acute Lymphoblastic Leukemia (B-ALL) BLOOD. 2019.11; 134 ( DOI )
Kadia, TM; Cortes, JE; Konopleva, MY; Borthakur, GM; Pemmaraju, N; Daver, NG; Bravo, GM; Issa, GC; Naqvi, K; Short, NJ; DiNardo, CD; Bhalla, KN; Jabbour, E; Takahashi, K; Sasaki, K; Kornblau, SM; Malla, R; Pierce, SA; Wang, XM; Estrov, ZE; Andreeff, M; Garcia-Manero, G; Ravandi, F; Kantarjian, HM: Venetoclax Combined with Cladribine plus Low Dose AraC (LDAC) Alternating with 5-Azacytidine Produces High Rates of Minimal Residual Disease (MRD) Negative Complete Remissions (CR) in Older Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) BLOOD. 2019.11; 134 ( DOI )
Rausch, CR; DiNardo, CD; Maiti, A; Jammal, N; Kadia, TM; Marx, K; Borthakur, GM; Savoy, JM; Pemmaraju, N; Dipippo, A; Daver, NG; Chew, S; Sasaki, K; Issa, GC; Naqvi, K; Ravandi, F; Kantarjian, HM; Konopleva, MY: Venetoclax Dosing in Combination with Antifungal Agents: Real World Experience in Patients with Acute Myeloid Leukemia BLOOD. 2019.11; 134 ( DOI )
Guerra, VA; Kantarjian, HM; Cortes, JE; Garcia-Manero, G; Masarova, L; Pemmaraju, N; Jabbour, E; Kadia, TM; DiNardo, CD; Zhou, LS; Pierce, SA; Borthakur, GM; Wierda, WG; Ferrajoli, A; Sasaki, K; Takahashi, K; Naqvi, K; Alvarado, Y; Ohanian, MN; Jain, N; Bose, P; Ravandi, F; Konopleva, MY; Estrov, ZE; Verstovsek, S; Daver, NG: A Phase II Trial of Azacitidine (AZA) in Combination with Ruxolitinib (RUX) in Myelodysplastic Syndrome/Myeloproliferative Neoplasms (MDS/MPNs) BLOOD. 2019.11; 134 ( DOI )
Cortes, J; Garcia-Manero, G; Sasaki, K; Naqvi, K; Alvarado, Y; Kadia, TM; Ravandi, F; Cortes, JE; Daver, NG; Takahashi, K; Jabbour, E; Borthakur, GM; Pemmaraju, N; Konopleva, MY; Pierce, SA; Bueso-Ramos, CE; Patel, KP; Kantarjian, HM; Bravo, GM: Activity of Venetoclax-Based Therapy in Myelodysplastic Syndrome (MDS) BLOOD. 2019.11; 134 ( DOI )
Cortes, J; Alfayez, M; Kadia, TM; Konopleva, MY; Ravandi, F; Cortes, JE; Jabbour, E; Garcia-Manero, G; Pierce, SA; Yilmaz, ME; Short, NJ; Sasaki, K; Masarova, L; Pemmaraju, N; Borthakur, GM; Kantarjian, HM; DiNardo, CD; Daver, NG: Activity of Multiple Targetable Therapies in FLT3-Mutated (mu) Acute Myeloid Leukemia (AML) Patients (pts) with Concurrent Isocitrate Dehydrogenase Mutation (IDHm) BLOOD. 2019.11; 134 ( DOI )
Daver, NG; Garcia-Manero, G; Konopleva, MY; Alfayez, M; Pemmaraju, N; Kadia, TM; DiNardo, CD; Cortes, JE; Ravandi, F; Abbas, H; Basu, S; Jabbour, E; Pierce, SA; Estrov, ZE; Takahashi, K; Ning, J; Kornblau, SM; Sasaki, K; Masarova, L; Flores, W; Allison, JP; Sharma, P; Kantarjian, HM: Azacitidine (AZA) with Nivolumab (Nivo), and AZA with Nivo plus Ipilimumab (Ipi) in Relapsed/Refractory Acute Myeloid Leukemia: A Non-Randomized, Prospective, Phase 2 Study BLOOD. 2019.11; 134 ( DOI )
Nogami Ayako, Watanabe Daisuke, Okada Keigo, Akiyama Hiroki, Umezawa Yoshihiro, Nagao Toshikage, Tohda Shuji, Miura Osamu: FLT3-ITD Enhances Proliferation and Survival of AML Cells through Activation of RSK1 to Upregulate the mTORC1/eIF4F Pathway Cooperatively with PIM or PI3K and to Inhibit Bad and Bim BLOOD. 2019.11; 134 ( DOI )
Jain, N; Keating, MJ; Thompson, PA; Burger, JA; Ferrajoli, A; Estrov, ZE; Borthakur, GM; Takahashi, K; Bose, P; Fowler, NH; Kadia, TM; Daver, NG; Konopleva, MY; Alvarado, Y; Yilmaz, M; DiNardo, CD; Ohanian, M; Pemmaraju, N; Jabbour, E; Sasaki, K; Kanagal-Shamanna, R; Patel, K; Jorgensen, JL; Wang, SA; Garg, N; Wang, XM; Sondermann, K; Cruz, N; Wei, CJ; Ayala, A; Plunkett, W; Kantarjian, HM; Gandhi, V; Wierda, WG: Combined Ibrutinib and Venetoclax in Patients with Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia (CLL) BLOOD. 2019.11; 134 ( DOI )
Jain, N; Keating, MJ; Thompson, PA; Ferrajoli, A; Burger, JA; Borthakur, GM; Takahashi, K; Estrov, ZE; Fowler, NH; Kadia, TM; Konopleva, MY; Alvarado, Y; Yilmaz, M; DiNardo, CD; Bose, P; Ohanian, M; Pemmaraju, N; Jabbour, E; Sasaki, K; Kanagal-Shamanna, R; Patel, K; Jorgensen, JL; Wang, SA; Garg, N; Wang, XM; Sondermann, K; Cruz, N; Wei, CJ; Ayala, A; Plunkett, W; Kantarjian, HM; Gandhi, V; Wierda, WG: Combined Ibrutinib and Venetoclax for First-Line Treatment for Patients with Chronic Lymphocytic Leukemia (CLL) BLOOD. 2019.11; 134 ( DOI )
Samra, B; Kantarjian, HM; Sasaki, K; Konopleva, MY; Khouri, R; O'Brien, SM; Ferrajoli, A; Nunez, C; Kadia, TM; Jabbour, E: Discontinuation of Tyrosine Kinase Inhibitors (TKIs) in Philadelphia Chromosome-Positive (Ph plus ) Acute Lymphoblastic Leukemia (ALL) BLOOD. 2019.11; 134 ( DOI )
The Detection of Minor Clones with Somatic KIT D816V Mutations Using Droplet Digital PCR in Pediatric De Novo AML: AML-05 Trial from the Japanese Pediatric Leukemia/Lymphoma Study Group 2019.11; 134 ( DOI )
Alfayez, M; Richard-Carpentier, G; Jabbour, E; Vishnu, P; Naqvi, K; Sasaki, K; Cortes, J; Pemmaraju, N: Sudden blastic transformation in treatment-free remission chronic myeloid leukaemia BRITISH JOURNAL OF HAEMATOLOGY. 2019.11; 187 (4): 543-545. ( PubMed , DOI )
Sasaki, K; Kantarjian, HM; Kadia, T; Patel, K; Loghavi, S; Garcia-Manero, G; Jabbour, EJ; DiNardo, C; Pemmaraju, N; Daver, N; Abou Dalle, I; Short, N; Yilmaz, M; Bose, P; Naqvi, K; Pierce, S; Yalniz, F; Cortes, JE; Ravandi, F: Sorafenib plus intensive chemotherapy improves survival in patients with newly diagnosed, FLT3-internal tandem duplication mutation-positive acute myeloid leukemia CANCER. 2019.11; 125 (21): 3755-3766. ( PubMed , DOI )
Sasaki, K; Kantarjian, HM; Ravandi, F; Short, NJ; Kebriaei, P; Huang, XL; Rytting, ME; Jain, N; Konopleva, MY; Garcia-Manero, G; Champlin, RE; Kadia, TM; Cortes, JE; Estrov, ZE; Takahashi, K; Loiselle, C; Encarnacion, C; Rostykus, M; Khouri, R; Nasnas, P; Jacob, J; Kwari, M; Garris, R; Jabbour, E: Sequential Combination of Inotuzumab Ozogamicin (InO) with Low-Intensity Chemotherapy (Mini-hyper-CVD) with or without Blinatumomab Is Highly Effective in Patients (pts) with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia (ALL) in First Relapse BLOOD. 2019.11; 134 ( DOI )
Sasaki, K; Kantarjian, HM; Jabbour, EJ: Reply to Mini-HCVD plus inotuzumab plus or minus blinatumomab: Hype or hope? CANCER. 2019.11; 125 (21): 3891-3892. ( PubMed , DOI )
Maiti, A; DiNardo, CD; Rausch, CR; Cortes, JE; Pemmaraju, N; Daver, NG; Ravandi, F; Garcia-Manero, G; Borthakur, GM; Naqvi, K; Ohanian, MN; Short, NJ; Alvarado, Y; Benton, CB; Kadia, TM; Takahashi, K; Yilmaz, ME; Jain, N; Kornblau, SM; Sasaki, K; Andreeff, M; Bose, P; Ferrajoli, A; Issa, GC; Jabbour, E; Masarova, L; Rytting, ME; Thompson, PA; Wang, SA; Konoplev, S; Chen, ZN; Goswami, M; Maduike, R; Guerrero, JA; Zhang, Q; Cavazos, A; Ma, H; Bivins, CA; Wade, A; Adewale, SL; Tse, S; Thomas, R; Vaughan, K; Pierce, SA; Ning, J; Qiao, W; Welch, JS; Kantarjian, HM; Konopleva, MY: Ten-Day Decitabine with Venetoclax (DEC10-VEN) in Acute Myeloid Leukemia: Updated Results of a Phase II Trial BLOOD. 2019.11; 134 ( DOI )
Sasaki, K; Ribera, JM; Figueroa, M; Ravandi, F; Short, NJ; Garcia-Manero, G; Daver, NG; Kadia, TM; Konopleva, MY; Jain, N; Issa, GC; Estrov, ZE; Garris, R; Khouri, R; Nasnas, P; DiNardo, CD; Naqvi, K; Kornblau, SM; Montalban-Bravo, G; Pemmaraju, N; Cortes, JE; O'Brien, SM; Chandra, J; Kantarjian, HM; Jabbour, E: The Impact of Smoking on Survival in Patients (Pts) with Newly Diagnosed Philadelphia Chromosome Positive (Ph plus ) Acute Lymphoblastic Leukemia (ALL) Treated with the Combination of Intensive Therapy with Tyrosine Kinase Inhibitor (TKI) BLOOD. 2019.11; 134 ( DOI )
Chien, KS; Kanagal-Shamanna, R; Naqvi, K; Sasaki, K; Alvarado, Y; Takahashi, K; Kadia, TM; Borthakur, GM; Jabbour, E; Routbort, M; Pierce, SA; Soltysiak, K; Kantarjian, HM; Garcia-Manero, G; Montalban-Bravo, G: The Impact of PHF6 Mutations in Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, and Acute Myeloid Leukemia BLOOD. 2019.11; 134 ( DOI )
Yilmaz, M; Kantarjian, HM; Wang, XM; Khoury, JD; Ravandi, F; Jorgensen, JL; Short, NJ; Loghavi, S; Cortes, JE; Garcia-Manero, G; Kadia, TM; Sasaki, K; Konopleva, MY; Takahashi, K; Wierda, WG; Jain, N; Verstovsek, S; Estrov, ZE; Bose, P; Pierce, SA; Garris, R; O'Brien, SM; Jabbour, E: The Early Achievement of Measurable Residual Disease Negativity in the Treatment of Adults with Philadelphia-Negative B-Cell Acute Lymphoblastic Leukemia Is a Strong Predictor for Survival BLOOD. 2019.11; 134 ( DOI )
Paul, S; Sasaki, K; Savoy, JM; Dipippo, A; Jammal, N; Marx, K; Kadia, TM; Garcia-Manero, G; Ravandi, F; Kantarjian, HM; Jabbour, E: Title: 12 Versus 8 Prophylactic Intrathecal (IT) Chemotherapy Administration Decrease Incidence of Central Nervous System (CNS) Relapse in Patients (pts) with Newly Diagnosed Philadelphia ( Ph)-Positive Acute Lymphocytic Leukemia (ALL) BLOOD. 2019.11; 134 ( DOI )
Sasaki, K; Kantarjian, HM; Jabbour, E; Ravandi, F; Konopleva, MY; Borthakur, GM; Wierda, WG; Daver, NG; Takahashi, K; Naqvi, K; DiNardo, CD; Bravo, GM; Kanagal-Shamanna, R; Pemmaraju, N; Issa, GC; Jain, P; Skinner, J; Rios, MB; Pierce, SA; Soltysiak, K; Sato, J; Garcia-Manero, G; Cortes, JE: The Impact of Treatment Recommendation By Leukemia Artificial Intelligence Program (LEAP) on Survival in Patients with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) BLOOD. 2019.11; 134 ( DOI )
Kanagal-Shamanna, R; Montalban-Bravo, G; Class, C; Sasaki, K; Benton, CB; Soltysiak, K; Jabbour, E; Kadia, TM; Bueso-Ramos, CE; Patel, KP; Routbort, M; Ganan-Gomez, I; Wei, Y; Borthakur, GM; Ravandi, F; Do, KA; Medeiros, LJ; Kantarjian, HM; Garcia-Manero, G: Evolutionary Action (EA) Score of TP53 Mutations Defines Prognostic Subsets within TP53 Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia BLOOD. 2019.11; 134 ( DOI )
Cortes, J; Kantarjian, HM; Richard-Carpentier, G; Borthakur, GM; Ravandi, F; Naqvi, K; Sasaki, K; Kadia, TM; Verstovsek, S; Garcia-Manero, G; DiNardo, CD; Pemmaraju, N; Daver, NG; Bose, P; Pierce, SA; Dara, S; Jabbour, E; Cortes, JE: Effectiveness of Bosutinib in Chronic Myeloid Leukemia (CML) Who Have Received Multi Tyrosine Kinase Inhibitors (TKIs) BLOOD. 2019.11; 134 ( DOI )
Kanagal-Shamanna, R; Montalban-Bravo, G; Sasaki, K; Luthra, R; Phdmd, HY; Toruner, GA; Patel, KP; Mallampati, S; Kantarjian, HM; Bueso-Ramos, CE; Medeiros, LJ; Garcia-Manero, G: High-Resolution Next-Generation Whole Genome Optical Mapping As a Novel Molecular Diagnostic Tool for Comprehensive Assessment of Structural Chromosomal Variations in Myelodysplastic Syndromes BLOOD. 2019.11; 134 ( DOI )
Montalban-Bravo, G; Kanagal-Shamanna, R; Benton, CB; Class, C; Chien, KS; Sasaki, K; Naqvi, K; Alvarado, Y; Kadia, TM; Ravandi, F; Cortes, JE; Daver, NG; Takahashi, K; DiNardo, CD; Jabbour, E; Borthakur, GM; Pemmaraju, N; Konopleva, MY; Pierce, SA; Bueso-Ramos, CE; Andreeff, M; Patel, KP; Kantarjian, HM; Garcia-Manero, G: Genomic Context and TP53 Allele Frequency Define Prognostic Subgroups and Response Outcomes in TP53 Mutated Myelodysplastic Syndromes BLOOD. 2019.11; 134 ( DOI )
Jain, N; Thompson, PA; Burger, JA; Ferrajoli, A; Takahashi, K; Estrov, ZE; Borthakur, GM; Bose, P; Kadia, TM; Pemmaraju, N; Sasaki, K; Garg, N; Wang, XM; Kanagal-Shamanna, R; Patel, K; Jorgensen, JL; Wang, SA; Lopez, W; Ayala, A; Plunkett, W; Gandhi, V; Kantarjian, HM; O'Brien, S; Keating, MJ; Wierda, WG: Ibrutinib, Fludarabine, Cyclophosphamide, and Obinutuzumab (iFCG) for First-Line Treatment of IGHV-Mutated CLL and without Del(17p)/Mutated TP53 BLOOD. 2019.11; 134 ( DOI )
Jabbour, E; Roberts, KG; Sasaki, K; Zhao, YQ; Qu, CX; Gu, ZH; Jain, N; Patel, KP; Ravandi, F; Short, NJ; Garcia-Manero, G; Garris, R; Kornblau, S; Konopleva, MY; Mullighan, CG; Kantarjian, HM: Inotuzumab Ozogamicin (Ino) May Overcome the Impact of Philadelphia Chromosome (Ph)-like Phenotype in Adult Patients (pts) with Relapsed/Refractory (R/R) Acute Lymphoblastic Leukemia (ALL) BLOOD. 2019.11; 134 ( DOI )
Perez, JMR; Kadia, TM; Montalban-Bravo, G; Benton, CB; Faderl, S; Sasaki, K; Naqvi, K; Cortes, JE; Daver, NG; DiNardo, CD; Jabbour, E; Borthakur, GM; Al Azzawi, H; Pemmaraju, N; Konopleva, MY; Pierce, SA; Jain, N; Ohanian, M; Garcia-Manero, G; Andreeff, M; Kantarjian, HM; Ravandi, F; Alvarado, Y: Liposomal Cytarabine and Daunorubicin (CPX-351) in Combination with Gemtuzumab Ozogamicin (GO) in Relapsed Refractory (R/R) Patients with Acute Myeloid Leukemia (AML) and Post-Hypomethylating Agent (Post-HMA) Failure High-Risk Myelodysplastic Syndrome (HR-MDS) BLOOD. 2019.11; 134 ( DOI )
Sasaki, K; Bravo, GM; Kanagal-Shamanna, R; Jabbour, E; Ravandi, F; Kadia, TM; Naqvi, K; Daver, NG; Pierce, SA; Takahashi, K; DiNardo, CD; González, GMN; Patel, K; Soltysiak, K; Sato, J; Cortes, JE; Kantarjian, HM; Garcia-Manero, G: Machine Learning Prediction for Complete Response to Hypomethylating Agents with or without Additional Agents in Patients with Newly Diagnosed Myelodysplastic Syndrome BLOOD. 2019.11; 134 ( DOI )
Sakhdari, A; Class, C; Montalban-Bravo, G; Sasaki, K; Bueso-Ramos, CE; Patel, KP; Khoury, JD; Kantarjian, HM; Garcia-Manero, G; Medeiros, LJ; Kanagal-Shamanna, R: Loss of EZH2 Protein Expression in Myelodysplastic Syndrome Correlates with EZH2 Mutation and Portends a Worse Outcome BLOOD. 2019.11; 134 ( DOI )
Short, NJ; Kantarjian, HM; Ravandi, F; Huang, XL; Daver, NG; DiNardo, CD; Konopleva, MY; Pemmaraju, N; Wierda, WG; Garcia-Manero, G; Sasaki, K; Cortes, JE; Garris, R; Ward, M; Huang, BR; Encarnacion, C; Loiselle, C; Khoury, JD; Jorgensen, JL; Jain, N; Alvarez, J; Tippett, N; O'Brien, SM; Jabbour, E: Long-Term Safety and Efficacy of Hyper-CVAD Plus Ponatinib As Frontline Therapy for Adults with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia BLOOD. 2019.11; 134 ( DOI )
Montalban-Bravo, G; Jabbour, E; Class, C; Short, NJ; Kanagal-Shamanna, R; Kadia, TM; Borthakur, GM; Pemmaraju, N; Sasaki, K; Estrov, ZE; Cortes, JE; Ravandi, F; Alvarado, Y; Komrokji, RS; Sekeres, MA; Steensma, DP; DeZern, AE; Roboz, GJ; Yang, H; Kantarjian, HM; Garcia-Manero, G: Long-Term Follow up of a Randomized Phase 2 Study of Low-Dose Decitabine Versus Low-Dose Azacitidine in Lower-Risk Myelodysplastic Syndromes BLOOD. 2019.11; 134 ( DOI )
Maiti, A; Rausch, CR; Cortes, JE; Pemmaraju, N; Daver, NG; Ravandi, F; Garcia-Manero, G; Borthakur, GM; Naqvi, K; Ohanian, M; Short, NJ; Alvarado, Y; Benton, CB; Kadia, TM; Takahashi, K; Yilmaz, M; Jain, N; Kornblau, SM; Sasaki, K; Andreeff, M; Bose, P; Ferrajoli, A; Issa, GC; Jabbour, E; Masarova, L; Rytting, ME; Thompson, PA; Wang, SA; Konoplev, S; Chen, ZN; Goswami, M; Maduike, R; Guerrero, JA; Zhang, Q; Cavazos, A; Ma, H; Bivins, CA; Wade, A; Adewale, SL; Tse, S; Thomas, R; Vaughan, K; Pierce, SA; Ning, J; Qiao, W; Welch, JS; Patel, KP; Kantarjian, HM; Konopleva, MY; DiNardo, CD: Outcomes in Molecular Subgroups and Resistance Patterns with Ten-Day Decitabine and Venetoclax (DEC10-VEN) in Acute Myeloid Leukemia BLOOD. 2019.11; 134 ( DOI )
Samra, B; Kantarjian, HM; Sasaki, K; Short, NJ; Khouri, R; Khoury, JD; Champlin, RE; Kebriaei, P; Cortes, JE; Jorgensen, JL; Wang, SA; Garcia-Manero, G; Kadia, TM; Borthakur, GM; Verstovsek, S; Daver, NG; Montalban-Bravo, G; Jain, N; Konopleva, MY; Yilmaz, ME; Naqvi, K; O'Brien, SM; Ravandi, F; Jabbour, E: Outcome of Patients (Pts) with Philadelphia Chromosome-Positive (Ph plus ) Acute Lymphoblastic Leukemia (ALL) without 3-Month Complete Molecular Response (CMR) BLOOD. 2019.11; 134 ( DOI )
Bravo, GM; Kanagal-Shamanna, R; Sasaki, K; Ravandi, F; Cortes, JE; Daver, NG; Takahashi, K; DiNardo, CD; Jabbour, E; Borthakur, GM; Naqvi, K; Konopleva, MY; Pierce, SA; Bueso-Ramos, CE; Patel, KP; Kantarjian, HM; Garcia-Manero, G; Kadia, TM: Outcomes of Patients with Acute Myeloid Leukemia (AML) with Myelodysplasia Related Changes (AML-MRC) Are Dependent on Diagnostic Criteria and Therapy BLOOD. 2019.11; 134 ( DOI )
Montalban-Bravo, G; Kanagal-Shamanna, R; Sasaki, K; Ravandi, F; Cortes, JE; Daver, NG; Takahashi, K; DiNardo, CD; Jabbour, E; Borthakur, GM; Naqvi, K; Konopleva, MY; Pierce, SA; Bueso-Ramos, CE; Patel, KP; Kantarjian, HM; Garcia-Manero, G; Kadia, TM: Outcomes of Patients with Acute Myeloid Leukemia with Myelodysplastic Are Dependent on Diagnostic Criteria and Therapy BLOOD. 2019.11; 134 ( DOI )
Masarova, L; Verstovsek, S; Bose, P; Pemmaraju, N; Cortes, JE; Jabbour, E; Ohanian, M; Zhou, LS; Pierce, SA; Gergis, R; Borthakur, GM; Kadia, TM; DiNardo, CD; Ravandi, F; Konopleva, MY; Naqvi, K; Sasaki, K; Estrov, ZE; Garcia-Manero, G; Bueso-Ramos, CE; Kantarjian, HM; Daver, NG: Phase 2 Study of Ruxolitinib (RUX) in Combination with 5-Azacitidine (AZA) in Patients (pts) with Myelofibrosis BLOOD. 2019.11; 134 ( DOI )
Maiti, A; Rausch, CR; Cortes, JE; Pemmaraju, N; Daver, NG; Ravandi, F; Garcia-Manero, G; Borthakur, GM; Naqvi, K; Ohanian, M; Short, NJ; Alvarado, Y; Benton, CB; Benton, CB; Kadia, TM; Takahashi, K; Yilmaz, ME; Jain, N; Kornblau, SM; Bravo, GM; Sasaki, K; Andreeff, M; Bose, P; Ferrajoli, A; Issa, GC; Jabbour, E; Masarova, L; Rytting, ME; Thompson, PA; Wang, SA; Konoplev, S; Chen, ZN; Goswami, M; Maduike, R; Guerrero, JA; Zhang, Q; Cavazos, A; Ma, H; Bivins, CA; Wade, A; Adewale, SL; Tse, S; Thomas, R; Vaughan, K; Pierce, SA; Ning, J; Qiao, W; Welch, JS; Kantarjian, HM; Konopleva, MY; DiNardo, CD: Outcomes of Relapsed or Refractory Acute Myeloid Leukemia after Frontline Hypomethylating Agent with Venetoclax Regimens BLOOD. 2019.11; 134 ( DOI )
Ahaneku, HO; Kantarjian, HM; González, GMN; Borthakur, GM; Verstovsek, S; Kadia, TM; Pemmaraju, N; Garcia-Manero, G; Konopleva, MY; DiNardo, CD; Naqvi, K; Sasaki, K; Issa, GC; Jabbour, E; Cortes, JE: Outcomes of Patients with Suboptimal /Warning Response to Tyrosine Kinase Inhibitors: A Comparison of the 2009 and 2013 Guidelines of the European Leukemianet BLOOD. 2019.11; 134 2930. ( DOI )
Nukui Y, Chino T, Tani C, Sonobe K, Aiso Y, Tohda S, Koike R, Saito R: Molecular epidemiologic and clinical analysis of Helicobacter cinaedi bacteremia in Japan. Helicobacter. 2019.11; e12675. ( PubMed , DOI )
Richard-Carpentier, G; Kantarjian, HM; Konopleva, MY; Patel, KP; Roberts, KG; Gu, ZH; Ravandi, F; Jain, N; Short, NJ; Garcia-Manero, G; Schroeder, HM; Kwari, M; Garris, R; Khouri, R; Jones, M; Loiselle, C; Cortes, JE; Sasaki, K; Issa, GC; Kadia, TM; DiNardo, CD; Verstovsek, S; Daver, NG; Mullighan, CG; O'Brien, SM; Jabbour, E: Phase II Study of the Hyper-CVAD Regimen in Combination with Ofatumumab (HCVAD-O) As Frontline Therapy for Adult Patients (pts) with CD20-Positive B-Cell Acute Lymphoblastic Leukemia (B-ALL) BLOOD. 2019.11; 134 ( DOI )
Richard-Carpentier, G; DeZern, AE; Takahashi, K; Konopleva, MY; Loghavi, S; Masarova, L; Alvarado, Y; Ravandi, F; Bravo, GM; Naqvi, K; Sasaki, K; Delumpa, R; Kwari, M; Sekeres, MA; Nazha, A; Roboz, GJ; Kantarjian, HM; Garcia-Manero, G; DiNardo, CD: Preliminary Results from the Phase II Study of the IDH2-Inhibitor Enasidenib in Patients with High-Risk IDH2-Mutated Myelodysplastic Syndromes (MDS) BLOOD. 2019.11; 134 ( DOI )
Ryoichi Saito, Yukino Usui, Alafate Ayibieke, Jun Nakajima, Isaac Prah, Kazunari Sonobe, Yoshibumi Aiso, Shiori Ito, Yasuhiro Itsui, Yoshiro Hadano, Yoko Nukui, Ryuji Koike, Shuji Tohda: Hypervirulent clade 2, ribotype 019/sequence type 67 Clostridioides difficile strain from Japan. Gut Pathog. 2019.11; 11 54. ( PubMed , DOI )
Sasaki, K; Kantarjian, HM; Samra, B; Short, NJ; Khoury, JD; Kanagal-Shamanna, R; Konopleva, MY; Jain, N; DiNardo, CD; Khouri, R; Garcia-Manero, G; Kadia, TM; Wierda, WG; Tippett, N; Garris, R; Jeanis, V; Daver, NG; Thompson, PA; Yilmaz, M; Cortes, JE; O'Brien, SM; Ravandi, F; Jabbour, E: Prognostic Factors for Progression in Patients (pts) with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph plus ALL) in Complete Molecular Response (CMR) within 3 Months of Therapy with Tyrosine Kinase Inhibitors (TKIs) BLOOD. 2019.11; 134 ( DOI )
Sasaki, Y; Short, NJ; Kantarjian, HM; Garris, R; Jain, N; Sasaki, K; Ravandi, F; Konopleva, MY; Rytting, ME; Garcia-Manero, G; Little, L; Gumbs, C; Zhao, L; Futreal, PA; Wang, F; Takahashi, K; Jabbour, E: Prognostic Significance of IKZF1, PAX5, and CDKN2A Deletions in Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Treated with Hyper-CVAD/MA with Dasatinib or Ponatinib BLOOD. 2019.11; 134 ( DOI )
Kaminaka S., Akaza M., Kawabata S., Watanabe T., Miyano Y., Iida S., Sasaki T., Adachi Y., Sekihara K., Kanouchi T., Sumi Y., Okawa A., Yokota T.: Diagnosis of C8 radiculopathy by magnetospinogram JOURNAL OF THE NEUROLOGICAL SCIENCES. 2019.10; 405 ( DOI )
Sasaki, K; Kantarjian, H; Richard-Carpentier, G; Ravandi, F; Short, N; Garcia-Manero, G; Daver, N; Kadia, T; Konopleva, M; Jain, N; Issa, G; Jeanis, V; Alvarez, J; Khouri, M; Nasnas, P; Garris, R; Wierda, W; Thompson, P; Pemmaraju, N; Cortes, J; O'Brien, S; Jabbour, E: Dynamic Prediction of Outcome with Longitudinal BCR-ABL1 Levels in Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019.09; 19 S180-S181.
Short, N; Kantarjian, H; Sasaki, K; Kanagal-Shamanna, R; Ravandi, F; Cortes, J; Konopleva, M; Issa, G; Kornblau, S; Garcia-Manero, G; Rivera, V; Garris, R; Salk, J; Prichard, J; Radich, J; Jabbour, E: Duplex Sequencing Identifies Low Level ABL1 Kinase Domain Mutations in Untreated Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019.09; 19 S186.
Short, N; Jabbour, E; Sasaki, K; Ravandi, F; Huang, XL; Kebriaei, P; Jain, N; Garcia-Manero, G; Kadia, T; Konopleva, M; Jacob, J; Garris, R; Cortes, J; O'Brien, S; Kantarjian, H: Reduced-Intensity Chemotherapy Plus Inotuzumab Ozogamicin, With or Without Sequential Blinatumomab, is Highly Effective as First Salvage Treatment in Patients with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019.09; 19 S186-S187.
Sasaki, K; Kantarjian, H; Richard-Carpentier, G; Ravandi, F; Short, N; Garcia-Manero, G; Daver, N; Kadia, T; Konopleva, M; Jain, N; Issa, G; Estrov, Z; Garris, R; Khouri, M; Nasnas, P; Pemmaraju, N; Cortes, J; O'Brien, S; Jabbour, E: The Impact of Smoking on Relapse and Survival in Patients with Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Treated with the Combination of Intensive Therapy with Tyrosine Kinase Inhibitor CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019.09; 19 S180.
Yilmaz, M; Kantarjian, H; Wang, XM; Loghavi, S; Khoury, J; Jorgensen, J; Ravandi, F; Short, N; Cortes, J; Garcia-Manero, G; Kadia, T; Sasaki, K; Konopleva, M; Takahashi, K; Wierda, W; Khouri, M; Jain, N; Verstovsek, S; Estrov, Z; Bose, P; Pierce, S; Garris, R; O'Brien, S; Jabbour, E: The Early Achievement of Measurable Residual Disease Negativity in the Treatment of Adults with Philadelphia-Negative B-Cell Acute Lymphoblastic Leukemia is a Strong Predictor for Survival CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019.09; 19 S193-S194. ( DOI )
Yilmaz, M; Kantarjian, H; Ravandi, F; Thomas, D; Khouri, M; Garcia-Manero, G; Garris, R; Cortes, J; Short, N; Sasaki, K; Issa, G; Koller, P; Schroeder, H; Kadia, T; Verstovsek, S; Daver, N; Jain, N; Konopleva, M; O'Brien, S; Jabbour, E: Hyper-CVAD Plus Ofatumumab as Frontline Therapy for Adults with CD20 Positive Acute Lymphoblastic Leukemia CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019.09; 19 S185. ( DOI )
Sasaki, K; Kantarjian, H; Richard-Carpentier, G; Short, N; Ravandi, F; Khouri, M; Garcia-Manero, G; Daver, N; Kadia, T; Konopleva, M; Jain, N; Issa, G; Jacob, J; Garris, R; Yilmaz, M; Thompson, P; Nasnas, P; Pemmaraju, N; Cortes, J; O'Brien, S; Jabbour, E: Inotuzumab Ozogamicin Combined with Low-Intensity, with or without Blinatumomab vs. Intensive Therapy for Older Patients with Newly Diagnosed Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia: A Propensity Score Analysis CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019.09; 19 S181. ( DOI )
Chien, K; Class, C; Bravo, GM; Sasaki, K; Naqvi, K; Gomez, IG; Wei, Y; Yang, H; Kanagal-Shamanna, R; Soltysiak, K; Kantarjian, H; Garcia-Manero, G: LILRB4 Expression in CMML and MDS Based on Response to Hypomethylating Agents CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019.09; 19 S341. ( DOI )
Yalniz, F; Abou Dalle, I; Kantarjian, H; Borthakur, G; Kadia, T; Patel, K; Loghavi, S; Garcia-Manero, G; Sasaki, K; Daver, N; DiNardo, C; Pemmaraju, N; Short, NJ; Yilmaz, M; Bose, P; Naqvi, K; Pierce, S; Gonzalez, GMN; Konopleva, M; Andreeff, M; Cortes, J; Ravandi, F: Prognostic significance of baseline FLT3-ITD mutant allele level in acute myeloid leukemia treated with intensive chemotherapy with/without sorafenib AMERICAN JOURNAL OF HEMATOLOGY. 2019.09; 94 (9): 984-991. ( PubMed , DOI )
Yoko Nukui, Alafate Ayibieke, Makoto Taniguchi, Yoshibumi Aiso, Yuka Shibuya, Kazunari Sonobe, Jun Nakajima, Saki Kanehira, Yoshiro Hadano, Shuji Tohda, Ryuji Koike, Ryoichi Saito: Whole-genome analysis of EC129, an NDM-5-, CTX-M-14-, OXA-10- and MCR-1-co-producing Escherichia coli ST167 strain isolated from Japan. J Glob Antimicrob Resist. 2019.09; 18 148-150. ( PubMed , DOI )
Itoh M, Okuhashi Y, Takahashi Y, Sonoda Y, Mohammad S, Saito T, Shiratori E, Tohda S: Hypoxia Up-regulates HIF Expression While Suppressing Cell Growth and NOTCH Activity in Leukaemia Cells. Anticancer research. 2019.08; 39 (8): 4165-4170. ( PubMed , DOI )
Jabbour, EJ; Sasaki, K; Ravandi, F; Short, NJ; Garcia-Manero, G; Daver, N; Kadia, T; Konopleva, M; Jain, N; Cortes, J; Issa, GC; Jacob, J; Kwari, M; Thompson, P; Garris, R; Pemmaraju, N; Yilmaz, M; O'Brien, SM; Kantarjian, HM: Inotuzumab ozogamicin in combination with low-intensity chemotherapy (mini-HCVD) with or without blinatumomab versus standard intensive chemotherapy (HCVAD) as frontline therapy for older patients with Philadelphia chromosome-negative acute lymphoblastic leukemia: A propensity score analysis CANCER. 2019.08; 125 (15): 2579-2586. ( PubMed , DOI )
Naqvi, K; Sasaki, K; Montalban-Bravo, G; Pierola, AA; Yilmaz, M; Short, N; Assi, R; Jabbour, E; Ravandi, F; Kadia, T; Pierce, S; Takahashi, K; Gonzalez, GN; Kanagal-Shamanna, R; Patel, K; Soltysiak, KA; Kantarjian, HM; Garcia-Manero, G: Clonal hematopoiesis of indeterminate potential-associated mutations and risk of comorbidities in patients with myelodysplastic syndrome CANCER. 2019.07; 125 (13): 2233-2241. ( PubMed , DOI )
Horiuchi Y., Ohkawa R., Lai S., Shimano S., Hagihara M., Tohda S., Tozuka M.: Availability of ApoB-depleted serum in clinical assay for cholesterol efflux capacity using immobilized liposome-bound gel beads CLINICA CHIMICA ACTA. 2019.06; 493 S78-S79. ( DOI )
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Sasaki, K; Kantarjian, HM; O'Brien, S; Ravandi, F; Konopleva, M; Borthakur, G; Garcia-Manero, G; Wierda, WG; Daver, N; Ferrajoli, A; Takahashi, K; Jain, P; Rios, MB; Pierce, SA; Jabbour, EJ; Cortes, JE: Incidence of second malignancies in patients with chronic myeloid leukemia in the era of tyrosine kinase inhibitors INTERNATIONAL JOURNAL OF HEMATOLOGY. 2019.05; 109 (5): 545-552. ( PubMed , DOI )
Chien, KS; Class, CA; Montalban-Bravo, G; Sasaki, K; Naqvi, K; Gomez, IG; Wei, Y; Yang, H; Kanagal-Shamanna, R; Kantarjian, HM; Garcia-Manero, G: LILRB4 expression in CMML and MDS based on response to hypomethylating agents. JOURNAL OF CLINICAL ONCOLOGY. 2019.05; 37 (15):
Chien, KS; Benton, CB; Class, CA; Kadia, TM; Dinardo, CD; Konopleva, M; Andreeff, M; Sasaki, K; Naqvi, K; Gomez, IG; Wei, Y; Yang, H; Pierce, SA; Patel, KP; Kanagal-Shamanna, R; Kantarjian, HM; Garcia-Manero, G; Montalban-Bravo, G: Patterns of leukemic transformation in patients with TP53-mutant myelodysplastic syndromes. JOURNAL OF CLINICAL ONCOLOGY. 2019.05; 37 (15):
Montalban-Bravo, G; Kanagal-Shamanna, R; Sasaki, K; Patel, K; Ganan-Gomez, I; Jabbour, E; Kadia, T; Ravandi, F; Dinardo, C; Borthakur, G; Takahashi, K; Konopleva, M; Komrokji, RS; DeZern, A; Kuzmanovic, T; Maciejewski, J; Pierce, S; Colla, S; Sekeres, MA; Kantarjian, H; Bueso-Ramos, C; Garcia-Manero, G: NPM1 mutations define a specific subgroup of MDS and MDS/MPN patients with favorable outcomes with intensive chemotherapy BLOOD ADVANCES. 2019.03; 3 (6): 922-933. ( PubMed , DOI )
Jain, P; Kantarjian, H; Boddu, PC; Nogueras-González, GM; Verstovsek, S; Garcia-Manero, G; Borthakur, G; Sasaki, K; Kadia, TM; Sam, P; Ahaneku, H; O'Brien, S; Estrov, Z; Ravandi, F; Jabbour, E; Cortes, JE: Analysis of cardiovascular and arteriothrombotic adverse events in chronic-phase CML patients after frontline TKIs BLOOD ADVANCES. 2019.03; 3 (6): 851-861. ( PubMed , DOI )
Yuna Horiuchi, Ryunosuke Ohkawa, Shao-Jui Lai, Shitsuko Shimano, Michio Hagihara, Shuji Tohda, Takahiro Kameda, Minoru Tozuka: Usefulness of apolipoprotein B-depleted serum in cholesterol efflux capacity assays using immobilized liposome-bound gel beads. Biosci. Rep.. 2019.03; ( PubMed , DOI )
Hamada S, Hasegawa Y, Oono A, Suzuki A, Takahashi N, Nishimura T, Koyama T, Hagihara M, Tohda S, Furukawa T, Hirao K, Sasano T: Author Correction: Differential Assessment of Factor Xa Activity and Global Blood Coagulability Utilizing Novel Dielectric Coagulometry. Scientific reports. 2019.03; 9 (1): 4957. ( PubMed , DOI )
Nogami Ayako, Okada Keigo, Ishida Shinya, Akiyama Hiroki, Umezawa Yoshihiro, Miura Osamu: Inhibition of the STAT5/Pim Kinase Axis Enhanecs Cytotoxic Effects of Proteasome Inhibitors on FLT3-ITD-Positive Cells by Cooperatively Inhibiting the mTORC1/4EBP1/S6K/Mcl-1 Pathway TRANSLATIONAL ONCOLOGY. 2019.02; 12 (2): 336-349. ( PubMed , DOI )
Short, NJ; Jabbour, E; Naqvi, K; Patel, A; Ning, J; Sasaki, K; Nogueras-Gonzalez, GM; Bose, P; Kornblau, SM; Takahashi, K; Andreeff, M; Sanchez-Petitto, G; Estrov, Z; Dinardo, CD; Montalban-Bravo, G; Konopleva, M; Alvarado, Y; Bhalla, KN; Fiskus, W; Khouri, M; Islam, R; Kantarjian, H; Garcia-Manero, G: A phase II study of omacetaxine mepesuccinate for patients with higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia after failure of hypomethylating agents AMERICAN JOURNAL OF HEMATOLOGY. 2019.01; 94 (1): 74-79. ( PubMed , DOI )
Hu, B; Thall, P; Milton, DR; Sasaki, K; Bashir, Q; Shah, N; Patel, K; Popat, U; Hosing, C; Nieto, Y; Lin, P; Delgado, R; Jorgensen, J; Manasanch, E; Weber, D; Thomas, S; Orlowski, RZ; Champlin, R; Qazilbash, MH: High-risk myeloma and minimal residual disease postautologous-HSCT predict worse outcomes LEUKEMIA & LYMPHOMA. 2019.01; 60 (2): 442-452. ( PubMed , DOI )
Kawaguchi-Ihara Noriko, Zhao Yan, Nakamura Suzune, Suzuki Keiko, Zhang Yi, Tohda Shuji, Murohashi Ikuo: Chloroquine Inhibits Self-Renewal of Blast Progenitors Synergistically With Phytochemicals or Nonsteroidal Anti-inflammatory Drugs in Hematological Malignant Cell Lines ANTICANCER RESEARCH. 2019.01; 39 (1): 87-98. ( PubMed , DOI )
Akiyama Hiroki, Umezawa Yoshihiro, Ishida Shinya, Okada Keigo, Nogami Ayako, Miura Osamu: Inhibition of USP9X induces apoptosis in FLT3-ITD-positive AML cells cooperatively by inhibiting the mutant kinase through aggresomal translocation and inducing oxidative stress CANCER LETTERS. 2019; 453 84-94. ( PubMed , DOI )
Jabbour, E; Short, NJ; Ravandi, F; Huang, XL; Daver, N; DiNardo, CD; Konopleva, M; Pemmaraju, N; Wierda, W; Garcia-Manero, G; Sasaki, K; Cortes, J; Garris, R; Khoury, JD; Jorgensen, J; Jain, N; Alvarez, J; O'Brien, S; Kantarjian, H: Combination of hyper-CVAD with ponatinib as first-line therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia: long-term follow-up of a single-centre, phase 2 study LANCET HAEMATOLOGY. 2018.12; 5 (12): E618-E627. ( PubMed , DOI )
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Sasaki, K; Jabbour, EJ; Ravandi, F; Short, NJ; Garcia-Manero, G; Daver, NG; Kadia, TM; Konopleva, MY; Jain, N; Issa, GC; Jeanis, V; Alvarez, J; Khouri, M; Nasnas, P; Garris, RE; Wierda, WG; Thompson, PA; Pemmaraju, N; Cortes, JE; O'Brien, SM; Kantarjian, HM: Dynamic Personalized Assessment of Outcome in Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia BLOOD. 2018.11; 132 ( DOI )
Short, NJ; Kantarjian, HM; Sasaki, K; Ravandi, F; Cortes, JE; Konopleva, MY; Issa, GC; Kanagal-Shamanna, R; Kornblau, SM; Garcia-Manero, G; Rivera, V; Garris, RE; Salk, J; Prichard, J; Radich, JP; Jabbour, EJ: Ultrasensitive Duplex Sequencing of Pretreatment ABL1 Kinase Domain Mutations in Patients with Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia BLOOD. 2018.11; 132 ( DOI )
Rausch, CR; Paul, S; Kantarjian, HM; Ravandi, F; Short, NJ; Sasaki, K; Khouri, M; Jacob, J; Montalbano, KS; Thompson, PA; Jain, N; Yilmaz, M; Naqvi, K; Ohanian, MN; Nasnas, P; Estrov, ZE; O'Brien, SM; Jabbour, EJ: Utility of Leucovorin Rescue in Patients with Acute Lymphoblastic Leukemia (ALL) Treated with the Mini-Hypercvd Regimen BLOOD. 2018.11; 132 ( DOI )
Richard-Carpentier, G; Kantarjian, HM; Short, NJ; Ravandi, F; Ferrajoli, A; Schroeder, HM; Khouri, M; Garcia-Manero, G; Bravo, GM; Cortes, JE; Jain, N; Konopleva, MY; Takahashi, K; Sasaki, K; Garris, RE; Jabbour, EJ: A Phase II Study of the Hyper-CVAD Regimen in Sequential Combination with Blinatumomab As Frontline Therapy for Adults with B-Cell Acute Lymphoblastic Leukemia (B-ALL) BLOOD. 2018.11; 132 ( DOI )
Garcia-Manero, G; Sasaki, K; Montalban-Bravo, G; Daver, NG; Jabbour, EJ; Alvarado, Y; DiNardo, CD; Ravandi, F; Borthakur, G; Bose, P; Pemmaraju, N; Naqvi, K; Cortes, JE; Kadia, TM; Konopleva, MY; Colla, S; Yang, H; Rausch, CR; Gasior, Y; Bueso-Ramos, CE; Kanagal-Shamanna, R; Patel, KP; Kantarjian, HM: A Phase II Study of Nivolumab or Ipilimumab with or without Azacitidine for Patients with Myelodysplastic Syndrome (MDS) BLOOD. 2018.11; 132 ( DOI )
Short, NJ; Jabbour, EJ; Ravandi, F; Huang, XL; Jain, N; Sasaki, K; Pemmaraju, N; Daver, NG; Khoury, JD; Jorgensen, JL; Alvarado, Y; Konopleva, MY; Garcia-Manero, G; Kadia, TM; Yilmaz, M; Borthakur, G; Burger, JA; Kornblau, SM; Wierda, WG; DiNardo, CD; Ferrajoli, A; Nasnas, P; Jacob, J; Garris, RE; O'Brien, SM; Kantarjian, HM: Chemoimmunotherapy with Inotuzumab Ozogamicin Combined with Mini-Hyper-CVD, with or without Blinatumomab, for Newly Diagnosed Older Patients with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia: Results from a Phase II Study BLOOD. 2018.11; 132 ( DOI )
Naqvi, K; Sasaki, K; Montalban-Bravo, G; Teach, MS; Pierce, SA; Kantarjian, HM; Garcia-Manero, G: Characteristics and Role of Lenalidomide Therapy in Patients with Myelodysplastic/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis BLOOD. 2018.11; 132 ( DOI )
Jain, N; Keating, MJ; Thompson, PA; Ferrajoli, A; Burger, JA; Borthakur, G; Takahashi, K; Estrov, ZE; Fowler, NH; Kadia, TM; Konopleva, MY; Alvarado, Y; Yilmaz, M; DiNardo, CD; Bose, P; Ohanian, MN; Pemmaraju, N; Jabbour, EJ; Sasaki, K; Kanagal-Shamanna, R; Patel, K; Jorgensen, JL; Garg, N; Wang, XM; Sondermann, K; Cruz, N; Wei, CJ; Ayala, A; Plunkett, W; Kantarjian, HM; Gandhi, V; Wierda, WG: Combined Ibrutinib and Venetoclax in Patients with Treatment-Naive High-Risk Chronic Lymphocytic Leukemia (CLL) BLOOD. 2018.11; 132 ( DOI )
Nakamura, Y; Ichikawa, M; Oda, H; Yamazaki, I; Sasaki, K; Mitani, K: RUNX1-EVI1 induces dysplastic hematopoiesis and acute leukemia of the megakaryocytic lineage in mice LEUKEMIA RESEARCH. 2018.11; 74 14-20. ( PubMed , DOI )
Jabbour, EJ; Sasaki, K; Ravandi, F; Short, NJ; Garcia-Manero, G; Daver, NG; Kadia, TM; Konopleva, MY; Jain, N; Issa, GC; Estrov, ZE; Garris, RE; Khouri, M; Nasnas, P; Pemmaraju, N; Cortes, JE; O'Brien, SM; Kantarjian, HM: Smoking Confers Poor Survival in Patients (Pts) with Newly Diagnosed Philadelphia Chromosome Positive (Ph plus ) Acute Lymphoblastic Leukemia (ALL) Treated with the Combination of Intensive Therapy with Tyrosine Kinase Inhibitor (TKI) BLOOD. 2018.11; 132 ( DOI )
Sasaki, K; Kantarjian, HM; Ravandi, F; Short, NJ; Kebriaei, P; Huang, XL; Rytting, ME; Jain, N; Konopleva, MY; Garcia-Manero, G; Champlin, RE; Kadia, TM; Cortes, JE; Estrov, ZE; Takahashi, K; Mace, M; Khouri, M; Nasnas, P; Jacob, J; Garris, RE; Jabbour, EJ: Sequential Combination of Low-Intensity Chemotherapy (Mini-hyper-CVD) Plus Inotuzumab Ozogamicin with or without Blinatumomab in Patients with Relapsed/Refractory Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia (ALL): A Phase 2 Trial BLOOD. 2018.11; 132 ( DOI )
Sasaki, K; Kanagal-Shamanna, R; Montalban-Bravo, G; Assi, R; Naqvi, K; Pierola, AA; Yilmaz, M; Short, NJ; Jabbour, EJ; Ravandi, F; Kadia, TM; Pierce, SA; Takahashi, K; DiNardo, CD; González, GMN; Abaza, Y; Devendra, KC; Chamoun, K; Sakurai, K; Patel, KP; Cortes, JE; Kantarjian, HM; Garcia-Manero, G: The Impact of Clonal Hematopoiesis of Indeterminate Potential on Survival in Patients with Newly Diagnosed Acute Myeloid Leukemia BLOOD. 2018.11; 132 ( DOI )
Garcia-Manero, G; Sasaki, K; Montalban-Bravo, G; Bodden, KR; Bose, P; Alvarado, Y; Daver, NG; Borthakur, G; Ravandi, F; Takahashi, K; Cortes, JE; Jabbour, EJ; Naqvi, K; DiNardo, CD; Benton, CB; Pemmaraju, N; Kadia, TM; Ohanian, MN; Pierce, SA; Kantarjian, HM: Final Report of a Phase II Study of Guadecitabine (SGI-110) in Patients (pts) with Previously Untreated Myelodysplastic Syndrome (MDS) BLOOD. 2018.11; 132 ( DOI )
Kanagal-Shamanna, R; Sasaki, K; Bravo, GM; Benton, CB; Jabbour, EJ; Borthakur, G; Kadia, TM; Bueso-Ramos, CE; Patel, K; Ravandi, F; Kantarjian, HM; Garcia-Manero, G: Evolutionary Action Score of Missense TP53 Mutations Can Predict Outcome in Patients with Myelodysplastic Syndrome and Acute Myeloid Leukemia BLOOD. 2018.11; 132 ( DOI )
Swaminathan, M; Kantarjian, HM; Sasaki, K; Ravandi, F; Borthakur, G; Kadia, TM; Garcia-Manero, G; DiNardo, CD; Konopleva, MY; Estrov, ZE; Pemmaraju, N; Daver, NG; Wierda, WG; Ferrajoli, A; Pierce, SA; Dellasala, MDE; Jabbour, EJ; Cortes, JE: Efficacy of Ponatinib after Multiple Lines of Therapy for Chronic Myeloid Leukemia BLOOD. 2018.11; 132 ( DOI )
Naqvi, K; Sasaki, K; Montalban-Bravo, G; Alfonso, A; Yilmaz, M; Short, NJ; Assi, R; Jabbour, EJ; Ravandi, F; Kadia, TM; Pierce, SA; Takahashi, K; González, GMN; Kanagal-Shamanna, R; Patel, KP; Kantarjian, HM; Garcia-Manero, G: Imapct of Clonal Hematopoiesis of Indeterminate Potential (CHIP) Associated Mutations and Risk of Comorbidities in Patients with Myelodysplastic Syndrome BLOOD. 2018.11; 132 ( DOI )
Sasaki, K; Kantarjian, HM; Short, NJ; Ravandi, F; Khouri, M; Garcia-Manero, G; Daver, NG; Kadia, TM; Konopleva, MY; Jain, N; Issa, GC; Jacob, J; Garris, RE; Yilmaz, M; Thompson, PA; Nasnas, P; Pemmaraju, N; Cortes, JE; O'Brien, SM; Jabbour, EJ: Inotuzumab Ozogamicin in Combination with Low-Intensity Chemotherapy (mini-hyper-CVD) Vs. Standard Intensive Chemotherapy (hyper-CVAD) As Frontline Therapy for Older Patients with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia (ALL): A Propensity Score Analysis BLOOD. 2018.11; 132 ( DOI )
Montalban-Bravo, G; Benton, CB; Kanagal-Shamanna, R; Sasaki, K; Assi, R; Kadia, TM; Ravandi, F; Ganan-Gomez, I; Cortes, JE; Daver, NG; Takahashi, K; DiNardo, CD; Jabbour, EJ; Borthakur, G; Pemmaraju, N; Konopleva, MY; Pierce, SA; Bueso-Ramos, CE; Kornblau, SM; Patel, K; Colla, S; Kantarjian, HM; Andreeff, M; Garcia-Manero, G: Landscape of TP53 Abnormalities and Their Clinical Relevance in Patients with Myelodysplastic Syndromes and Acute Myeloid Leukemia BLOOD. 2018.11; 132 ( DOI )
Bose, P; McCue, D; Wiederhold, NP; Kadia, TM; Borthakur, G; Ravandi, F; Yilmaz, M; Takahashi, K; Thompson, PA; Pemmaraju, N; Daver, NG; Burger, JA; Cortes, JE; Garcia-Manero, G; Verstovsek, S; Konopleva, MY; Jain, N; DiNardo, CD; Alvarado, Y; Naqvi, K; Kornblau, SM; Ferrajoli, A; Wierda, WG; Estrov, ZE; Benton, CB; Masarova, L; Montalban-Bravo, G; Sasaki, K; Rausch, CR; Marx, K; Qiao, W; Huang, X; Bivins, CA; Pierce, SA; Kantarjian, HM; Kontoyiannis, DP: Isavuconazole (ISAV) As Primary Anti-Fungal Prophylaxis in Acute Myeloid Leukemia or Myelodysplastic Syndrome: An Open-Label Prospective Study BLOOD. 2018.11; 132 ( DOI )
Maiti, A; DiNardo, CD; Cortes, JE; Borthakur, G; Pemmaraju, N; Benton, CB; Kadia, TM; Takahashi, K; Naqvi, K; Ravandi, F; Alvarado, Y; Short, NJ; Daver, NG; Sasaki, K; Ohanian, MN; Garcia-Manero, G; Thompson, PA; Kornblau, SM; Masarova, L; Jain, N; Jabbour, EJ; Andreeff, M; Maduike, R; Guerrero, JA; Zhang, Q; Cavazos, A; Ma, H; Rausch, CR; Bivins, CA; Vaughan, K; Pierce, SA; Ning, J; Qiao, W; Welch, JS; Kantarjian, HM; Konopleva, MY: Interim Analysis of Phase II Study of Venetoclax with 10-Day Decitabine (DEC10-VEN) in Acute Myeloid Leukemia and Myelodysplastic Syndrome BLOOD. 2018.11; 132 ( DOI )
Aboudalle, I; Kantarjian, HM; Short, NJ; Ravandi, F; Sasaki, K; Garcia-Manero, G; Montalban-Bravo, G; Cortes, JE; Benton, CB; Issa, GC; Khouri, M; Nasnas, P; O'Brien, SM; Jabbour, EJ: Long Term Follow-up on Phase 2 Study on the Efficacy and Safety of Blinatumomab in Adult Patients with Relapsed Refractory B-Precursor Acute Lymphoblastic Leukemia BLOOD. 2018.11; 132 4017. ( DOI )
Bravo, GM; Kanagal-Shamanna, R; Benton, CB; Colla, S; Ganan-Gomez, I; Sasaki, K; Ravandi, F; Kadia, TM; Cortes, JE; Daver, NG; Takahashi, K; DiNardo, CD; Jabbour, EJ; Borthakur, G; Naqvi, K; Konopleva, MY; Pierce, SA; Bueso-Ramos, CE; Patel, K; Kantarjian, HM; Garcia-Manero, G: Mutational and Clonal Landscape of Acute Myeloid Leukemia with Myelodysplastic Related Changes BLOOD. 2018.11; 132 ( DOI )
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Yalniz, F; Kantarjian, HM; Kadia, TM; Garcia-Manero, G; Patel, K; Loghavi, S; Sasaki, K; Daver, NG; DiNardo, CD; Pemmaraju, N; Short, NJ; Yilmaz, M; Bose, P; Naqvi, K; Pierce, SA; Cortes, JE; Ravandi, F: Prognostic Significance of Baseline FLT3-ITD Mutant Allele Burden in Acute Myeloid Leukemia Treated with Intensive Chemotherapy with/without Sorafenib BLOOD. 2018.11; 132 ( DOI )
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Yuna Horiuchi, Shao-Jui Lai, Azusa Yamazaki, Ayaka Nakamura, Ryunosuke Ohkawa, Kouji Yano, Takahiro Kameda, Shigeo Okubo, Shitsuko Shimano, Michio Hagihara, Shuji Tohda, Minoru Tozuka: Validation and application of a novel cholesterol efflux assay using immobilized liposomes as a substitute for cultured cells. Biosci. Rep.. 2018.04; 38 (2): ( PubMed , DOI )
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Shinji Ogihara, Ryoichi Saito, Etsuko Sawabe, Takahiro Kozakai, Mari Shima, Yoshibumi Aiso, Toshihide Fujie, Yoko Nukui, Ryuji Koike, Michio Hagihara, Shuji Tohda: Molecular typing of methicillin-resistant Staphylococcus aureus: Comparison of PCR-based open reading frame typing, multilocus sequence typing, and Staphylococcus protein A gene typing. J. Infect. Chemother.. 2018.04; 24 (4): 312-314. ( PubMed , DOI )
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Incidence of Secondary Malignancies in Patients with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) in the Era of Tyrosine Kinase Inhibitors (TKI) 2017.12; 130
Isolated Extramedullary (EMD) Blastic Transformation of Chronic Myeloid Leukemia (CML-BP) in the TKI Era: Characteristics, Treatments and Outcomes 2017.12; 130
Prognostic Index for Survival in Adult Patients with Philadelphia-Negative B-Cell Acute Lymphoblastic Leukemia (ALL) 2017.12; 130
A Phase I/II Study of Inotuzumab Ozogamicin in Combination with Low-Intensity Chemotherapy (mini-hyper-CVD) for Older Patients with Newly Diagnosed Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia 2017.12; 130
Keigo Okada, Ayako Nogami, Shinya Ishida, Hiroki Akiyama, Cheng Chen, Yoshihiro Umezawa and Osamu Miura: FLT3-ITD induces expression of Pim kinases through STAT5 to confer resistance to the PI3K/Akt pathway inhibitors on leukemic cells by enhancing the mTORC1/Mcl-1 pathway Oncotarget. 2017.12; 9 8870-8886.
Assi, R; Kantarjian, HM; Khouri, R; Ravandi, F; Kebriaei, P; Short, NJ; Thomas, DA; Garcia-Manero, G; Champlin, RE; Kadia, T; Cortes, JE; Jain, N; Konopleva, M; Estrov, Z; Takahashi, K; Sasaki, K; Jacob, J; Manzoor, A; Garris, R; O'Brien, SM; Jabbour, EJ: Updated Results of the Phase II Trial of Inotuzumab Ozogamicin (INO) Combined with Mini-Hyper-CVD As Salvage Therapy for Relapsed/Refractory (R/R) B-Cell Acute Lymphoblastic Leukemia (B-ALL) BLOOD. 2017.12; 130
Short, NJ; Kantarjian, HM; Ravandi, F; Huang, X; Jain, N; Daver, N; Thomas, DA; Pemmaraju, N; Khouri, R; Khoury, JD; Jorgensen, JL; Alvarado, Y; Sasaki, K; Konopleva, M; Garcia-Manero, G; Kadia, T; Cortes, JE; Benton, CB; Borthakur, G; Burger, JA; Ohanian, M; Wierda, WG; Estrov, Z; Kornblau, S; DiNardo, CD; Ferrajoli, A; Jacob, J; Manzoor, A; Garris, R; O'Brien, SM; Jabbour, EJ: A Phase I/II Study of Inotuzumab Ozogamicin in Combination with Low-Intensity Chemotherapy (mini-hyper-CVD) for Older Patients with Newly Diagnosed Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia BLOOD. 2017.12; 130
Naqvi, K; Bravo, GM; Pierola, AA; Yilmaz, M; Sasaki, K; Short, NJ; Assi, R; Jabbour, EJ; Ravandi, F; Benton, CB; Kadia, T; Pierce, S; Borthakur, G; Daver, N; DiNardo, CD; Takahashi, K; Jain, N; Pemmaraju, N; González, GN; Kantarjian, HM; Garcia-Manero, G: Clonal Hematopoiesis of Indeterminate Potential - Associated Mutations and Risk of Comorbidities in Patients with Myelodysplastic Syndrome BLOOD. 2017.12; 130
Pattern of Mutational Changes in Patients with Chronic Phase CML Who Are Treated with Frontline TKI and Transform to Blast Phase CML 2017.12; 130
Sasaki, K; Nagasawa, F; Yoshida, K; Takeda, J; Shiraishi, Y; Chiba, K; Tanaka, H; Okada, A; Miyano, S; Ichikawa, M; Ogawa, S; Mitani, K: Contribution of MIR9 on Disease Progression of Chronic Myelogenous Leukemia BLOOD. 2017.12; 130
Dynamics of Measurable Disease at Remission Determines Survival in Patients (Pts) with Philadelphia Chromosome Negative B-Cell Acute Lymphoblastic Leukemia (ALL) 2017.12; 130
Hyper-CVAD Plus Ofatumumab As Frontline Therapy in CD20+Acute Lymphoblastic Leukemia: Updated Results of a Phase II Trial 2017.12; 130
Alqam, HM; Kantarjian, HM; Chihara, D; Sasaki, K; Jabbour, EJ; Cortes, JE: Survival Outcome of Secondary Solid Cancer in Patients with Chronic Myeloid Leukemia BLOOD. 2017.12; 130
Yilmaz, M; Devendra, KC; Akosile, MA; Khoury, JD; Short, NJ; Cortes, JE; Garcia-Manero, G; Ravandi, F; Kadia, T; Sasaki, K; Konopleva, M; Wierda, WG; Jain, N; Verstovsek, S; Estrov, Z; Pierce, S; O'Brien, SM; Jabbour, EJ; Kantarjian, HM: The Prognostic Significance of Translocation (1;19) in Adult Patients (Pts) with B-Cell Acute Lymphoblastic Leukemia (ALL) BLOOD. 2017.12; 130
Yilmaz, M; Jabbour, EJ; Wang, XM; Loghavi, S; Khoury, JD; Jorgensen, JL; Ravandi, F; Short, NJ; Cortes, JE; Garcia-Manero, G; Kadia, T; Sasaki, K; Konopleva, M; Takahashi, K; Khouri, M; Jain, N; Verstovsek, S; Estrov, Z; Estrov, Z; Bose, P; Pierce, S; Garris, R; O'Brien, SM; Kantarjian, HM: Dynamics of Measurable Disease at Remission Determines Survival in Patients (Pts) with Philadelphia Chromosome Negative B-Cell Acute Lymphoblastic Leukemia (ALL) BLOOD. 2017.12; 130
Yoshihiro Umezawa, Hiroki Akiyama, Keigo Okada, Shinya Ishida, Ayako Nogami, Gaku Oshikawa, Tetsuya Kurosu, Osamu Miura: Molecular mechanisms for enhancement of stromal cell-derived factor 1-induced chemotaxis by platelet endothelial cell adhesion molecule 1 (PECAM-1). Journal of Biological Chemistry. 2017.12; 292 (48): 19639-19655.
Maiti, A; Kantarjian, HM; Ravandi, F; Khouri, M; Thomas, DA; Garcia-Manero, G; Garris, R; Cortes, JE; Short, NJ; Jain, N; Bose, P; Verstovsek, S; Konopleva, M; Sasaki, K; Issa, GC; Ghosn, M; Schroeder, HM; Kadia, T; Daver, N; O'Brien, SM; Jabbour, EJ: Hyper-CVAD Plus Ofatumumab As Frontline Therapy in CD20+Acute Lymphoblastic Leukemia: Updated Results of a Phase II Trial BLOOD. 2017.12; 130
Sasaki, K; Kantarjian, HM; O'Brien, SM; Ravandi, F; Konopleva, M; Borthakur, G; Garcia-Manero, G; Wierda, WG; Daver, N; Ferrajoli, A; Takahashi, K; Jain, P; Rios, MB; Pierce, S; Jabbour, EJ; Cortes, JE: Incidence of Secondary Malignancies in Patients with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) in the Era of Tyrosine Kinase Inhibitors (TKI) BLOOD. 2017.12; 130
Ghorab, A; Jain, P; Kantarjian, HM; Kanagal-Shamanna, R; Jabbour, EJ; Sasaki, K; Kadia, T; Garcia-Manero, G; Bose, P; Yilmaz, M; Naqvi, K; Wierda, WG; Verstovsek, S; Jain, N; Estrov, Z; Ravandi, F; O'Brien, SM; Cortes, JE: Isolated Extramedullary (EMD) Blastic Transformation of Chronic Myeloid Leukemia (CML-BP) in the TKI Era: Characteristics, Treatments and Outcomes BLOOD. 2017.12; 130
Jain, P; Kanagal-Shamanna, R; Kantarjian, HM; Lucas, FAS; Ghorab, A; Jabbour, EJ; Ghayas, I; Sasaki, K; Kadia, T; Estrov, Z; Ravandi, F; Cortes, JE: Pattern of Mutational Changes in Patients with Chronic Phase CML Who Are Treated with Frontline TKI and Transform to Blast Phase CML BLOOD. 2017.12; 130
Sasaki, K; Jabbour, EJ; Khouri, M; Thomas, DA; Garcia-Manero, G; Ravandi, F; Borthakur, G; Short, NJ; Issa, GC; Kadia, T; Jones, E; Garris, R; Cortes, JE; O'Brien, SM; Kantarjian, HM: Phase II Study of Hyper-Cmad with Liposomal Vincristine (Marqibo) for Patients with Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) BLOOD. 2017.12; 130
Yilmaz, M; Kantarjian, HM; Wang, XM; Devendra, KC; Khoury, JD; Ravandi, F; Short, NJ; Cortes, JE; Garcia-Manero, G; Kadia, T; Sasaki, K; Konopleva, M; Wierda, WG; Khouri, M; Jain, N; Verstovsek, S; Estrov, Z; Bose, P; Pierce, S; Garris, R; O'Brien, SM; Jabbour, EJ: Prognostic Index for Survival in Adult Patients with Philadelphia-Negative B-Cell Acute Lymphoblastic Leukemia (ALL) BLOOD. 2017.12; 130
The Prognostic Significance of Translocation (1;19) in Adult Patients (Pts) with B-Cell Acute Lymphoblastic Leukemia (ALL) 2017.12; 130
Phase II Study of Hyper-Cmad with Liposomal Vincristine (Marqibo) for Patients with Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) 2017.12; 130
Shuta Toru, Tadashi Kanouchi, Takanori Yokota, Yosuke Yagi, Akira Machida, Takayoshi Kobayashi: Utility of Autonomic Function Tests to Differentiate Dementia with Lewy Bodies and Parkinson Disease with Dementia from Alzheimer Disease. Eur. Neurol.. 2017.11; 79 (1-2): 27-32. ( PubMed , DOI )
Jabbour, E; Short, NJ; Ravandi, F; Huang, XL; Xiao, LC; Garcia-Manero, G; Plunkett, W; Gandhi, V; Sasaki, K; Pemmaraju, N; Daver, NG; Borthakur, G; Jain, NT; Konopleva, M; Estrov, Z; Kadia, TM; Wierda, WG; DiNardo, CD; Brandt, M; O'Brien, SM; Cortes, JE; Kantarjian, H: A Randomized Phase 2 Study of Idarubicin and Cytarabine With Clofarabine or Fludarabine in Patients With Newly Diagnosed Acute Myeloid Leukemia CANCER. 2017.11; 123 (22): 4430-4439. ( PubMed , DOI )
Issa, GC; Kantarjian, HM; Gonzalez, GN; Borthakur, G; Tang, GL; Wierda, W; Sasaki, K; Short, NJ; Ravandi, F; Kadia, T; Patel, K; Luthra, R; Ferrajoli, A; Garcia-Manero, G; Rios, MB; Dellasala, S; Jabbour, E; Cortes, JE: Clonal chromosomal abnormalities appearing in Philadelphia chromosome-negative metaphases during CML treatment BLOOD. 2017.11; 130 (19): 2084-2091. ( PubMed , DOI )
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Kanouchi T., Sekiguchi T., Iida S., Akaza M., Yokota T.: Temporal relation between local disease progression in the onset site and regional spread of motor symptoms in amyotrophic lateral sclerosis JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 558-559. ( DOI )
Kanai K., Yokota T., Shibuya K., Nakazato T., Kanouchi T., Iwai Y., Oyama G., Shimo Y., Shimizu T., Hattori N., Kuwabara S.: Increased motor axonal persistent sodium currents is associated with rapid regional spreading in amyotrophic lateral sclerosis JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 558. ( DOI )
Arai, H; Ichikawa, M; Furuichi, S; Nagasawa, F; Takahashi, W; Handa, T; Nakamura, Y; Nakamura, Y; Sasaki, K; Mitani, K: Non-Hodgkin's lymphoma of the breast: a review of 6 cases including 3 patients with a history of autoimmune diseases ANNALS OF ONCOLOGY. 2017.10; 28
Kanagal-Shamanna, R; Jain, P; Takahashi, K; Short, NJ; Tang, GL; Issa, GC; Ravandi, F; Garcia-Manero, G; Yin, CC; Luthra, R; Patel, KP; Khoury, JD; Montalban-Bravo, G; Sasaki, K; Kadia, TM; Borthakur, G; Konopleva, M; Jain, N; Garris, R; Pierce, S; Wierda, W; Estrov, Z; Cortes, J; O'Brien, S; Kantarjian, HM; Jabbour, E: TP53 Mutation Does Not Confer a Poor Outcome in Adult Patients With Acute Lymphoblastic Leukemia Who Are Treated With Frontline Hyper-CVAD-Based Regimens CANCER. 2017.10; 123 (19): 3717-3724. ( PubMed , DOI )
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Jabbour, E; Short, NJ; Montalban-Bravo, G; Huang, XL; Bueso-Ramos, C; Qiao, W; Yang, H; Zhao, C; Kadia, T; Borthakur, G; Pemmaraju, N; Sasaki, K; Estrov, Z; Cortes, J; Ravandi, F; Alvarado, Y; Komrokji, R; Sekeres, MA; Steensma, DP; DeZern, A; Roboz, G; Kantarjian, H; Garcia-Manero, G: Randomized phase 2 study of low-dose decitabine vs low-dose azacitidine in lower-risk MDS and MDS/MPN BLOOD. 2017.09; 130 (13): 1514-1522. ( PubMed , DOI )
Maiti, A; Kantarjian, H; Ravandi, F; Thomas, D; Khouri, M; Garcia-Manero, G; Garris, R; Cortes, J; Short, N; Sasaki, K; Issa, G; Koller, P; Schroeder, H; Kadia, T; Verstovsek, S; Daver, N; Jain, N; Konopleva, M; O'Brien, S; Jabbour, E: Frontline Ofatumumab with Hyper-CVAD in CD20+Acute Lymphoblastic Leukemia (ALL): Updated Results of a Phase II Trial CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2017.09; 17 S256-S257. ( DOI )
Maiti, A; Kantarjian, H; O'Brien, S; Ravandi, F; Short, N; Thomas, D; Garcia-Manero, G; Daver, N; Borthakur, G; Jain, N; Konopleva, M; Sasaki, K; Pemmaraju, N; Alvarado, Y; Jacob, J; Garris, R; Thompson, P; Cortes, J; Jabbour, E: Frontline Inotuzumab Ozogamicin with Low-intensity Chemotherapy (mini-hyper-CVD) in Older Patients with Acute Lymphoblastic Leukemia (ALL): Updated Results of a Phase I/II Trial CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2017.09; 17 S255-S256. ( DOI )
Maiti, A; Kantarjian, H; Ravandi, F; Short, N; Daver, N; Pemmaraju, N; Thomas, D; Yilmaz, M; Kadia, T; Sasaki, K; Garris, R; Garcia-Manero, G; DiNardo, C; Konopleva, M; Estrov, Z; Jain, N; Weirda, W; Jeanis, V; Cortes, J; O'Brien, S; Jabbour, E: Hyper-CVAD Plus Ponatinib as Frontline Therapy in Philadelphia Chromosome-Positive (Ph plus ) Acute Lymphoblastic Leukemia (ALL): Updated Results of a Phase II Trial CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2017.09; 17 S257-S258. ( DOI )
Sasaki, K; Jabbour, E; O'Brien, S; Thomas, D; Garcia-Manero, G; Ravandi, F; Borthakur, G; Short, N; Issa, G; Gachimova, E; Garris, R; Cortes, J; Kantarjian, H: Phase II study of hyper-CMAD with Liposomal Vincristine (Marqibo) for Patients with Newly Diagnosed Acute Lymphoblastic Leukemia CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2017.09; 17 S266. ( DOI )
Mika Ohtaka, Mai Itoh, Shuji Tohda: BMI1 Inhibitors Down-regulate NOTCH Signaling and Suppress Proliferation of Acute Leukemia Cells. Anticancer Res.. 2017.08; 37 (11): 6047-6053. ( PubMed , DOI )
Erika Shiratori, Mai Itoh, Shuji Tohda: MYD88 Inhibitor ST2825 Suppresses the Growth of Lymphoma and Leukaemia Cells. Anticancer Res.. 2017.07; 37 (11): 6203-6209. ( PubMed , DOI )
Short, N; Kantarjian, H; Ravandi, F; Daver, N; Pemmaraju, N; Thomas, D; Yilmaz, M; Kadia, T; Sasaki, K; Garris, R; Garcia-Manero, G; DiNardo, C; Konopleva, M; Estrov, Z; Jain, N; Wierda, W; Jeanis, V; Cortes, J; O'Brien, S; Jabbour, E: UPDATED RESULTS OF A PHASE II STUDY OF HYPER-CVAD PLUS PONATINIB AS FRONTLINE THERAPY FOR ADULTS WITH PHILADELPHIA CHROMOSOME-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA HAEMATOLOGICA. 2017.06; 102 198.
Short, N; Kantarjian, H; Ravandi, F; Huang, X; Xiao, L; Garcia-Manero, G; Plunkett, W; Gandhi, V; Sasaki, K; Pemmaraju, N; Daver, N; Borthakur, G; Jain, N; Konopleva, M; Estrov, Z; Kadia, T; Wierda, W; DiNardo, C; Brandt, M; O'Brien, S; Cortes, J; Jabbour, E: A RANDOMIZED PHASE II STUDY OF IDARUBICIN AND CYTARABINE WITH EITHER CLOFARABINE OR FLUDARABINE IN ADULTS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA HAEMATOLOGICA. 2017.06; 102 53.
Short, N; Kantarjian, H; O'Brien, S; Ravandi, F; Thomas, D; Garcia-Manero, G; Daver, N; Borthakur, G; Jain, N; Konopleva, M; Sasaki, K; Pemmaraju, N; Alvarado, Y; Jacob, J; Garris, R; Thompson, P; Cortes, J; Jabbour, E: INOTUZUMAB OZOGAMICIN IN COMBINATION WITH LOW-INTENSITY CHEMOTHERAPY (MINI-HYPER-CVD) AS FRONTLINE THERAPY FOR OLDER PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA: UPDATED RESULTS FROM A PHASE I/II TRIAL HAEMATOLOGICA. 2017.06; 102 34-35.
Short, NJ; Kantarjian, HM; O'Brien, SM; Ravandi, F; Thomas, DA; Garcia-Manero, G; Daver, NG; Borthakur, G; Jain, N; Konopleva, M; Sasaki, K; Pemmaraju, N; Alvarado, Y; Jacob, J; Garris, R; Thompson, PA; Cortes, JE; Jabbour, E: Updated results of a phase I/II study of inotuzumab ozogamicin in combination with low-intensity chemotherapy (mini-hyper-CVD) as frontline therapy for older patients with acute lymphoblastic leukemia. JOURNAL OF CLINICAL ONCOLOGY. 2017.05; 35 ( DOI )
Maiti, A; Kantarjian, HM; Ravandi, F; Thomas, DA; Khouri, M; Garcia-Manero, G; Garris, RS; Cortes, JE; Short, NJ; Sasaki, K; Issa, GC; Koller, PB; Schroeder, HM; Kadia, TM; Verstovsek, S; Daver, NG; Jain, N; Konopleva, M; O'Brien, SM; Jabbour, E: Updated results of frontline ofatumumab-hyper-CVAD in adults with CD20+acute lymphoblastic leukemia. JOURNAL OF CLINICAL ONCOLOGY. 2017.05; 35 ( DOI )
Short, NJ; Kantarjian, HM; Ravandi, F; Daver, NG; Pemmaraju, N; Thomas, DA; Yilmaz, M; Kadia, TM; Sasaki, K; Garris, R; Garcia-Manero, G; Dinardo, CD; Konopleva, M; Estrov, Z; Jain, N; Wierda, WG; Jeanis, V; Cortes, JE; O'Brien, SM; Jabbour, E: Frontline hyper-CVAD plus ponatinib for patients with Philadelphia chromosome positive acute lymphoblastic leukemia: Updated results of a phase II study. JOURNAL OF CLINICAL ONCOLOGY. 2017.05; 35 ( DOI )
Assi, R; Kantarjian, HM; Ravandi, F; O'Brien, SM; Kebriaei, P; Thomas, DA; Garcia-Manero, G; Khouri, IF; Champlin, RE; Kadia, TM; Cortes, JE; Jain, N; Konopleva, M; Khouri, R; Estrov, Z; Takahashi, K; Sasaki, K; Jacob, J; Garris, R; Jabbour, E: Inotuzumab ozogamicin (IO) combined with mini-hyper-CVD as salvage therapy for patients (pts) with R/R acute lymphoblastic leukemia (ALL). JOURNAL OF CLINICAL ONCOLOGY. 2017.05; 35 ( DOI )
Yuki Okuhashi, Mai Itoh, Shuji Tohda: Hedgehog Stimulation Suppresses Clonogenicity and Activates NOTCH Signalling in T-lymphoblastic Leukaemia Jurkat Cells. Anticancer Res.. 2017.05; 37 (9): 5005-5009. ( PubMed , DOI )
S Nogami, N Kawaguchi-Ihara, E Shiratori, M Ohtaka, M Itoh, S Tohda: Detection of the MYD88 mutation by the combination of the allele-specific PCR and quenching probe methods. Int J Lab Hematol. 2017.04; 39 (2): 163-168. ( PubMed , DOI )
Gettys, SC; Gulbis, A; Wilhelm, K; Sasaki, K; Dinh, Y; Rondon, G; Qazilbash, MH: Modified CVAD and modified CBAD compared to high-dose cyclophosphamide for peripheral blood stem cell mobilization in patients with multiple myeloma EUROPEAN JOURNAL OF HAEMATOLOGY. 2017.04; 98 (4): 388-392. ( PubMed , DOI )
Short, NJ; Kantarjian, HM; Sasaki, K; Ravandi, F; Ko, H; Yin, CC; Garcia-Manero, G; Cortes, JE; Garris, R; O'Brien, SM; Patel, K; Khouri, M; Thomas, D; Jain, N; Kadia, TM; Daver, NG; Benton, CB; Issa, GC; Konopleva, M; Jabbour, E: Poor outcomes associated with+1der(22) t(9;22) and-9/9p in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia receiving chemotherapy plus a tyrosine kinase inhibitor AMERICAN JOURNAL OF HEMATOLOGY. 2017.03; 92 (3): 238-243. ( PubMed , DOI )
Jabbour, E; Faderl, S; Sasaki, K; Kadia, T; Daver, N; Pemmaraju, N; Patel, K; Khoury, JD; Bueso-Ramos, C; Bohannan, Z; Ravandi, F; Borthakur, G; Verstovsek, S; Miller, D; Maduike, R; Hosing, C; Kantarjian, HM; Garcia-Manero, G: Phase 2 Study of Low-Dose Clofarabine Plus Cytarabine for Patients With Higher-Risk Myelodysplastic Syndrome Who Have Relapsed or Are Refractory to Hypomethylating Agents CANCER. 2017.02; 123 (4): 629-637. ( PubMed , DOI )
Issa, GC; Kantarjian, HM; Yin, CC; Qiao, W; Ravandi, F; Thomas, D; Short, NJ; Sasaki, K; Garcia-Manero, G; Kadia, TM; Cortes, JE; Daver, N; Borthakur, G; Jain, N; Konopleva, M; Khouri, I; Kebriaei, P; Champlin, RE; Pierce, S; O'Brien, SM; Jabbour, E: Prognostic impact of pretreatment cytogenetics in adult Philadelphia chromosome-negative acute lymphoblastic leukemia in the era of minimal residual disease CANCER. 2017.02; 123 (3): 459-467. ( PubMed , DOI )
Jabbour, E; Short, NJ; Jorgensen, JL; Yilmaz, M; Ravandi, F; Wang, SA; Thomas, DA; Khoury, J; Champlin, RE; Khouri, I; Kebriaei, P; O'Brien, SM; Garcia-Manero, G; Cortes, JE; Sasaki, K; Dinardo, CD; Kadia, TM; Jain, N; Konopleva, M; Garris, R; Kantarjian, HM: Differential Impact of Minimal Residual Disease Negativity According to the Salvage Status in Patients With Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia CANCER. 2017.01; 123 (2): 294-302. ( PubMed , DOI )
Miyako Murakawa, Yasuhiro Asahina, Hiroko Nagata, Mina Nakagawa, Sei Kakinuma, Sayuri Nitta, Fukiko Kawai-Kitahata, Satoshi Otani, Shun Kaneko, Masato Miyoshi, Tomoyuki Tsunoda, Yu Asano, Ayako Sato, Yasuhiro Itsui, Seishin Azuma, Toshihiko Nouchi, Yohei Furumoto, Tooru Asano, Yoshimichi Chuganji, Shuji Tohda, Mamoru Watanabe: ITPA gene variation and ribavirin-induced anemia in patients with genotype 2 chronic hepatitis C treated with sofosbuvir plus ribavirin. Hepatol. Res.. 2017.01; ( PubMed , DOI )
Iwasawa Eri, Ohkubo Takuya, Kanouchi Tadashi, Kanda Takashi, Mizusawa Hidehiro, Yokota Takanori: Long-term Effects of Intravenous Cyclophosphamide in Combination with Mesna Provided Intravenously and via Bladder Perfusion in a Patient with Severe Multifocal Motor Neuropathy INTERNAL MEDICINE. 2017; 56 (14): 1893-1896. ( PubMed , DOI )
Short, NJ; Jabbour, EJ; Sasaki, K; Ko, HD; Ravandi, F; Yin, CC; Khouri, MR; Cortes, JE; Garris, R; O'Brien, SM; Patel, KP; Garcia-Manero, G; Thomas, DA; Daver, N; Naqvi, K; Bose, P; Jain, N; Konopleva, M; Kantarjian, HM: Additional Chromosomal Abnormalities in Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Treated with Tyrosine Kinase Inhibitors: Differential Outcomes According to Type of Chromosomal Abnormality BLOOD. 2016.12; 128 (22): ( DOI )
Short, NJ; Kantarjian, HM; Jorgensen, JL; Ravandi, F; Yilmaz, M; Khouri, MR; Wang, S; Thomas, DA; Khoury, JD; Champlin, RE; Khouri, IF; Kebriaei, P; Marin, D; O'Brien, SM; Garcia-Manero, G; Cortes, JE; Sasaki, K; DiNardo, CD; Kadia, TM; Jain, N; Konopleva, M; Garris, R; Jabbour, EJ: Achievement of Minimal Residual Disease Negativity By Multiparameter Flow Cytometry Is an Important Therapeutic Endpoint in Patients with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia Receiving Salvage Treatment BLOOD. 2016.12; 128 (22): ( DOI )
Jabbour, EJ; Short, NJ; Huang, X; Maiti, A; Kadia, TM; Daver, N; Borthakur, G; DiNardo, CD; Pemmaraju, N; Sasaki, K; Estrov, Z; Verstovsek, S; Ravandi, F; Alvarado, Y; Sekeres, MA; Komrokji, RS; Steensma, DP; DeZern, AE; Roboz, GJ; Miller, D; Dong, X; Kantarjian, HM; Garcia-Manero, G: A Randomized Phase II Study of Low-Dose Decitabine Versus Azacitidine in Patients with Low- or Intermediate-1-Risk Myelodysplastic Syndromes: A Report on Behalf of the MDS Clinical Research Consortium BLOOD. 2016.12; 128 (22): ( DOI )
Sasaki, K; Kantarjian, HM; Jabbour, EJ; O'Brien, S; Ravandi, F; Konopleva, M; Borthakur, G; Wierda, WG; Daver, N; Takahashi, K; Jain, P; Skinner, J; Rios, MB; Pierce, S; Garcia-Manero, G; Cortes, JE: Clinical Application of Artificial Intelligence in Patients with Chronic Myeloid Leukemia in Chronic Phase BLOOD. 2016.12; 128 (22): ( DOI )
Kanagal-Shamanna, R; Jain, P; Luthra, R; Patel, KP; Garcia-Manero, G; Takahashi, K; Ravandi, F; Sasaki, K; Kadia, TM; Borthakur, G; Konopleva, M; Jain, N; Garris, R; Pierce, S; Estrov, Z; Wierda, WG; O'Brien, SM; Cortes, JE; Kantarjian, HM; Jabbour, EJ: Clinical Implications of TP53 Mutations in Adult Patients with Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) Treated with the Hypercvad-Based Regimens BLOOD. 2016.12; 128 (22): ( DOI )
Jain, P; Kantarjian, HM; Ravandi, F; Kanagal-Shamanna, R; Khoury, JD; Patel, KP; Garcia-Manero, G; Konopleva, M; Jain, N; Sasaki, K; Kadia, TM; Borthakur, G; Garris, R; Pierce, S; Estrov, Z; Wierda, WG; Cortes, JE; O'Brien, SM; Jabbour, EJ: Clinical Characteristics and Outcomes of Newly Diagnosed Patients with Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Lymphoblastic Lymphoma (T-LL) with Hypercvad Based Regimens BLOOD. 2016.12; 128 (22): ( DOI )
Jabbour, EJ; Kantarjian, HM; Sasaki, K; Kadia, TM; Ravandi, F; Cortes, JE; Khoury, JD; Patel, KP; Bueso-Ramos, CE; Daver, NG; Borthakur, G; Jain, N; DiNardo, CD; Konopleva, M; Verstovsek, S; Pemmaraju, N; Estrov, Z; Miller, D; Maduike, R; Faderl, S; Garcia-Manero, G: Clofarabine Plus Low-Dose Cytarabine for the Treatment of Patients with Higher-Risk Myelodysplastic Syndrome (MDS) Who Have Been Relapsing after, or Are Refractory to, Hypomethylating Agent (HMA) Therapy BLOOD. 2016.12; 128 (22): ( DOI )
Miyako Murakawa, Yasuhiro Asahina, Fukiko Kawai-Kitahata, Mina Nakagawa, Sayuri Nitta, Satoshi Otani, Hiroko Nagata, Shun Kaneko, Yu Asano, Tomoyuki Tsunoda, Masato Miyoshi, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Yasuhito Tanaka, Sayuki Iijima, Kaoru Tsuchiya, Namiki Izumi, Shuji Tohda, Mamoru Watanabe: Hepatic IFNL4 expression is associated with non-response to interferon-based therapy through the regulation of basal interferon-stimulated gene expression in chronic hepatitis C patients. [Epub ahead of print] J. Med. Virol.. 2016.12; ( PubMed , DOI )
Gene Igawa, Mika Casey, Etsuko Sawabe, Yoko Nukui, Shu Okugawa, Kyoji Moriya, Ryuji Koike, Shuji Tohda, Ryoichi Saito: Comparison of agar dilution and broth microdilution methods for Clostridium difficile antimicrobial susceptibility testing. J Glob Antimicrob Resist. 2016.12; 43-45. ( PubMed , DOI )
Koji Sasaki, Elias J Jabbour, Farhad Ravandi, Nicholas J Short, Deborah A Thomas, Guillermo Garcia-Manero, Naval G Daver, Tapan M Kadia, Marina Y Konopleva, Nitin Jain, Ghayas C Issa, Vicki Jeanis, Haim G Moore, Rebecca S Garris, Naveen Pemmaraju, Jorge E Cortes, Susan M O'Brien, Hagop M Kantarjian: Hyper-CVAD plus ponatinib versus hyper-CVAD plus dasatinib as frontline therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia: A propensity score analysis. Cancer. 2016.12; 122 (23): 3650-3656. ( PubMed , DOI )
Jain, P; Kantarjian, HM; Jabbour, EJ; Gonzalez, GN; Garcia-Manero, G; Kanagal-Shamanna, R; Patel, KP; Hu, SM; DellaSala, SE; Pierce, S; Sasaki, K; Konopleva, M; Wierda, WG; Daver, N; Kadia, TM; Borthakur, G; Estrov, Z; Ravandi, F; O'Brien, SM; Cortes, JE: Factors Affecting Survival Outcomes in Patients with Blast Phase CML (CML-BP) in the Tyrosine Kinase Inhibitor (TKI) Era: A Cohort Study of 498 Patients BLOOD. 2016.12; 128 (22): ( DOI )
Sasaki, K; Kantarjian, HM; Ravandi, F; Daver, N; Kadia, TM; Khouri, RB; Alvarado, Y; Burger, JA; Thomas, DA; Garcia-Manero, G; DiNardo, CD; Pemmaraju, N; Short, NJ; Schroeder, H; Garris, R; Bose, P; Jain, N; Naqvi, K; Wierda, WG; Verstovsek, S; Cortes, JE; Konopleva, M; O'Brien, SM; Jabbour, EJ: Frontline Ofatumumab in Combination with Hyper-CVAD for Adult Patients with CD-20 Positive Acute Lymphoblastic Leukemia (ALL): Interim Result of a Phase II Clinical Trial BLOOD. 2016.12; 128 (22): ( DOI )
Sasaki, K; Jabbour, EJ; O'Brien, SM; Ravandi, F; Thomas, DA; Garcia-Manero, G; Daver, N; Borthakur, G; Jain, N; Konopleva, M; Short, NJ; Pemmaraju, N; Alvarado, Y; Jacob, J; Garris, R; Thompson, PA; Cortes, JE; Kantarjian, HM: Inotuzumab Ozogamicin in Combination with Low-Intensity Chemotherapy (mini-hyper-CVD) As Frontline Therapy for Older Patients with Acute Lymphoblastic Leukemia (ALL): Interim Result of a Phase II Clinical Trial BLOOD. 2016.12; 128 (22): ( DOI )
Patel, YB; Voit, KN; Sasaki, K; Ravandi, F; Thomas, DA; O'Brien, SM; Borthakur, G; Garcia-Manero, G; Cortes, JE; Konopleva, M; Jain, N; Ohanian, M; Garris, R; Jacob, J; Kantarjian, HM; Jabbour, EJ: Methotrexate Clearance in Adult Patients with B-Precursor Acute Lymphoblastic Leukemia Treated with the Mini-Hyper-CVD Regimen BLOOD. 2016.12; 128 (22):
Sasaki, K; Jabbour, EJ; O'Brien, SM; Thomas, DA; Ravandi, F; Garcia-Manero, G; Cortes, JE; Short, NJ; Verstovsek, S; Yilmaz, M; Wierda, WG; Borthakur, G; Kadia, TM; Konopleva, M; Khouri, MR; Ferrajoli, A; Daver, NG; Pemmaraju, N; DiNardo, CD; Jain, N; Benton, CB; Takahashi, K; Naqvi, K; Bose, P; Kornblau, SM; Andreeff, M; Keating, MJ; Freireich, EJ; Kantarjian, HM: Outcome of Patients with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia (ALL) By Age Group over 35 Years: A Single Institution Experience BLOOD. 2016.12; 128 (22): ( DOI )
Sasaki, K; Jabbour, EJ; Ravandi, F; Daver, NG; Pemmaraju, N; Thomas, DA; Khouri, RB; Yilmaz, M; Kadia, TM; Short, NJ; Garris, R; Garcia-Manero, G; DiNardo, CD; Konopleva, M; Estrov, Z; Jain, N; Wierda, WG; Jeanis, TV; Cortes, JE; O'Brien, SM; Kantarjian, HM: Phase II Study of the Frontline Hyper-CVAD in Combination with Ponatinib for Patients with Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia BLOOD. 2016.12; 128 (22): ( DOI )
Sasaki, K; Kantarjian, HM; O'Brien, S; Ravandi, F; Konopleva, M; Borthakur, G; Garcia-Manero, G; Wierda, WG; Daver, N; Ferrajoli, A; Takahashi, K; Jain, P; Rios, MB; Pierce, S; Jabbour, EJ; Cortes, JE: Prediction for Sustained Deep Molecular Response of BCR-ABL Levels in Patients with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) BLOOD. 2016.12; 128 (22): ( DOI )
Sasaki, K; Jabbour, EJ; O'Brien, SM; Ravandi, F; Thomas, DA; Kadia, TM; Garcia-Manero, G; Burger, JA; Pemmaraju, N; Alvarado, Y; Daver, NG; Jain, N; Konopleva, M; Champlin, RE; Khouri, IF; Kebriaei, P; Marin, D; DiNardo, CD; Estrov, Z; Takahashi, K; Short, NJ; Khouri, MR; Jacob, J; Garris, R; Cortes, JE; Kantarjian, HM: Phase II Study of the Salvage Mini-Hyper-CVD in Combination with Inotuzumab Ozogamicin (INO) for Adult Patients with Relapsed/Refractory (R/R) Acute Lymphoblastic Leukemia (ALL) BLOOD. 2016.12; 128 (22): ( DOI )
Short, NJ; Kantarjian, HM; Sasaki, K; Cortes, JE; Ravandi, F; Thomas, DA; Garcia-Manero, G; Khouri, I; Kebriaei, P; Champlin, RE; Pierce, S; Issa, GC; Konopleva, M; Kadia, TM; Bueso-Ramos, C; Khoury, JD; Jain, N; O'Brien, SM; Jabbour, E: Prognostic Significance of Day 14 Bone Marrow Evaluation in Adults With Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia CANCER. 2016.12; 122 (24): 3812-3820. ( PubMed , DOI )
Takahashi, K; Kantarjian, HM; Yang, YL; Sasaki, K; Jain, P; DellaSala, S; Ravandi, F; Kadia, T; Pemmaraju, N; Daver, N; Borthakur, G; Garcia-Manero, G; Jabbour, E; Cortes, JE: A Propensity Score Matching Analysis of Dasatinib and Nilotinib as a Frontline Therapy for Patients With Chronic Myeloid Leukemia in Chronic Phase CANCER. 2016.11; 122 (21): 3336-3343. ( PubMed , DOI )
Koji Sasaki, Elias Jabbour, Jorge Cortes, Tapan Kadia, Guillermo Garcia-Manero, Gautam Borthakur, Preetesh Jain, Sherry Pierce, Naval Daver, Koichi Takahashi, Susan O'Brien, Hagop Kantarjian, Farhad Ravandi: Outcome of Patients With Therapy-Related Acute Myeloid Leukemia With or Without a History of Myelodysplasia. Clin Lymphoma Myeloma Leuk. 2016.11; 16 (11): 616-624. ( PubMed , DOI )
Shinji Ogihara, Ryoichi Saito, Etsuko Sawabe, Michio Hagihara, Shuji Tohda: First Japanese case of infectious endocarditis due to Enterococcus faecalis small-colony variants. J. Infect. Chemother. 2016.10; 22 (10): 716-719. ( PubMed , DOI )
Tamamyan, GN; Kantarjian, HM; Ning, J; Jain, P; Sasaki, K; McClain, KL; Allen, CE; Pierce, SA; Cortes, JE; Ravandi, F; Konopleva, MY; Garcia-Manero, G; Benton, CB; Chihara, D; Rytting, ME; Wang, S; Abdelall, W; Konoplev, SN; Daver, NG: Malignancy-associated hemophagocytic lymphohistiocytosis in adults: Relation to hemophagocytosis, characteristics, and outcomes CANCER. 2016.09; 122 (18): 2857-2866. ( PubMed , DOI )
Koji Sasaki, Hagop Kantarjian, Elias Jabbour, Farhad Ravandi, Koichi Takahashi, Marina Konopleva, Gautam Borthakur, Guillermo Garcia-Manero, William Wierda, Naval Daver, Preetesh Jain, Toshihisa Satta, Sherry Pierce, May Beth Rios, Jorge E Cortes: Frontline therapy with high-dose imatinib versus second generation tyrosine kinase inhibitor in patients with chronic-phase chronic myeloid leukemia - a propensity score analysis. Haematologica. 2016.08; 101 (8): e324-e327. ( PubMed , DOI )
Hiroko Nagata, Mina Nakagawa, Yuki Nishimura-Sakurai, Yu Asano, Tomoyuki Tsunoda, Masato Miyoshi, Shun Kaneko, Fumio Goto, Satoshi Otani, Fukiko Kawai-Kitahata, Miyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Naoko Tojo, Shuji Tohda, Yasuhiro Asahina, Mamoru Watanabe, : Serial measurement of Wisteria floribunda agglutinin positive Mac-2-binding protein is useful for predicting liver fibrosis and the development of hepatocellular carcinoma in chronic hepatitis C patients treated with IFN-based and IFN-free therapy.[Epub ahead of print] Hepatol Int. 2016.07; ( PubMed , DOI )
Short, NJ; Jabbour, E; Sasaki, K; Patel, K; O'Brien, SM; Cortes, JE; Garris, R; Issa, GC; Garcia-Manero, G; Luthra, R; Thomas, D; Kantarjian, H; Ravandi, F: Impact of complete molecular response on survival in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia BLOOD. 2016.07; 128 (4): 504-507. ( PubMed , DOI )
Yoshihiro Umezawa, Tetsuya Kurosu, Hiroki Akiyama, Nang Wu, Ayako Nogami, Toshikage Nagao, Osamu Miusa: Down regulation of Chk1 by p53 plays a role in synergistic induction of apoptosis by chemotherapeutics and inhibitors for Jak2 or BCR/ABL in hematopoietic cells. Oncotarget. 2016.06; ( PubMed )
Issa, GC; Kantarjian, HM; Ravandi, F; Thomas, DA; Khouri, M; Garcia-Manero, G; Garris, RS; Cortes, JE; Short, NJ; Sasaki, K; Schroeder, HM; Kadia, TM; Verstovsek, S; Daver, NG; Jain, N; Konopleva, M; O'Brien, SM; Jabbour, E: Updated results from the phase II study of hyper-CVAD in combination with ofatumumab as frontline therapy for adults with CD20 positive (CD20+) acute lymphoblastic leukemia (ALL). JOURNAL OF CLINICAL ONCOLOGY. 2016.05; 34 (15): ( DOI )
Sasaki, K; Kantarjian, HM; Ravandi, F; Thomas, DA; Cortes, JE; Pemmaraju, N; Kadia, TM; Short, NJ; Issa, GC; Garris, RS; Jeanis, V; Moore, HG; Garcia-Manero, G; Borthakur, G; Wierda, WG; Gachimova, E; O'Brien, SM; Jabbour, E: Updated results from phase II study of combination of hyper-CVAD (HCVAD) with ponatinib in frontline therapy of patients (pts) with Philadelphia chromosome-positive (Ph plus ) acute lymphoblastic leukemia (ALL). JOURNAL OF CLINICAL ONCOLOGY. 2016.05; 34 (15): ( DOI )
Short, NJ; Kantarjian, HM; Sasaki, K; Ravandi, F; Garcia-Manero, G; Thomas, DA; Pierce, S; Issa, GC; Cortes, JE; Kadia, TM; Jain, N; O'Brien, SM; Jabbour, E: xPrognostic significance of day 14 (D14) bone marrow (BM) assessment in adult patients receiving induction for Philadelphia chromosome-negative (Ph-) acute lymphoblastic leukemia (ALL). JOURNAL OF CLINICAL ONCOLOGY. 2016.05; 34 (15): ( DOI )
Hu, B; Sasaki, K; Bashir, Q; Shah, N; Patel, KK; Popat, UR; Hosing, C; Nieto, Y; Lin, P; Delgado, R; Jorgensen, JL; Shah, JJ; Manasanch, EE; Weber, DM; Thomas, SK; Orlowski, RZ; Champlin, RE; Qazilbash, MH: Depth of response post autologous hematopoietic stem cell transplantation (auto-HCT) to predict outcome in high risk multiple myeloma (MM). JOURNAL OF CLINICAL ONCOLOGY. 2016.05; 34 (15): ( DOI )
Short, NJ; Jabbour, E; Cortes, JE; Garris, R; O'Brien, SM; Patel, K; Sasaki, K; Issa, GC; Garcia-Manero, G; Thomas, DA; Kantarjian, HM; Ravandi, F: Impact of complete molecular response (CMR) on survival in patients with Philadelphia chromosome positive (Ph plus ) acute lymphoblastic leukemia (ALL). JOURNAL OF CLINICAL ONCOLOGY. 2016.05; 34 (15): ( DOI )
Issa, GC; Kantarjian, HM; Yin, CC; Ravandi, F; Garcia-Manero, G; Thomas, DA; Cortes, JE; Short, NJ; Sasaki, K; Qiao, W; Takahashi, K; Pierce, S; Verstovsek, S; Kadia, TM; Borthakur, G; O'Brien, SM; Jabbour, E: Prognostic impact of pre-treatment cytogenetics in adult acute lymphoblastic leukemia (ALL). JOURNAL OF CLINICAL ONCOLOGY. 2016.05; 34 (15): ( DOI )
Sasaki, K; Kantarjian, HM; Ravandi, F; Thomas, DA; Daver, NG; Kadia, TM; Konopleva, M; Jain, N; Short, NJ; Issa, GC; Jeanis, V; Moore, HG; Garris, RS; Garcia-Manero, G; Cortes, JE; O'Brien, SM; Jabbour, E: Propensity score analysis: Frontline therapy with hyper-CVAD (HCVAD) plus ponatinib vs. HCVAD plus dasatinib in patients (pts) with Philadelphia chromosome-positive (Ph plus ) acute lymphoblastic leukemia (ALL). JOURNAL OF CLINICAL ONCOLOGY. 2016.05; 34 (15): ( DOI )
Jain, P; Kantarjian, H; Sasaki, K; Jabbour, E; Dasarathula, J; Gonzalez, GN; Verstovsek, S; Borthakur, G; Wierda, W; Kadia, T; Dellasala, S; Pierce, S; Ravandi, F; O'Brien, S; Cortes, J: Analysis of 2013 European LeukaemiaNet (ELN) responses in chronic phase CML across four frontline TKI modalities and impact on clinical outcomes BRITISH JOURNAL OF HAEMATOLOGY. 2016.04; 173 (1): 114-126. ( PubMed , DOI )
Noriko Kawaguchi-Ihara, Mai Itoh, Ikuo Murohashi, Shuji Tohda: Establishment of a quenching probe method for detection of NPM1 mutations in acute myeloid leukemia cells. Oncol Lett. 2016.04; 11 (4): 2429-2432. ( PubMed , DOI )
Ramlal, R; Sasaki, K; Cerrada, SL; Srour, SA; Chen, JLN; Rondon, RG; Rezvani, K; Oran, B; Olson, A; Shpall, EJ; Champlin, RE; Ciurea, SO: Viral Reactivation in Haploidentical Transplants Using Post-Transplantation Cyclophosphamide - a Single Institution Experience BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. 2016.03; 22 (3): S375-S376. ( DOI )
Sasaki, K; Lahoti, A; Jabbour, E; Jain, P; Pierce, S; Borthakur, G; Daver, N; Kadia, T; Pemmaraju, N; Ferrajoli, A; O'Brien, S; Kantarjian, H; Cortes, J: Clinical Safety and Efficacy of Nilotinib or Dasatinib in Patients With Newly Diagnosed Chronic-Phase Chronic Myelogenous Leukemia and Pre-Existing Liver and/or Renal Dysfunction CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2016.03; 16 (3): 152-162. ( PubMed , DOI )
Jain, P; Kantarjian, H; Patel, KP; Gonzalez, GN; Luthra, R; Shamanna, RK; Sasaki, K; Jabbour, E; Romo, CG; Kadia, TM; Pemmaraju, N; Daver, N; Borthakur, G; Estrov, Z; Ravandi, F; O'Brien, S; Cortes, J: Impact of BCR-ABL transcript type on outcome in patients with chronic-phase CML treated with tyrosine kinase inhibitors BLOOD. 2016.03; 127 (10): 1269-1275. ( PubMed , DOI )
Qazilbash, MH; Chen, J; Valdez, BC; Sasaki, K; Kawedia, JD; Bashir, Q; Hosing, C; Kebriaei, P; Nieto, Y; Shah, N; Patel, K; Shpall, EJ; Andersson, BS; Champlin, RE; Popat, U: Myeloablative Timed Sequential Busulfan Is Safe in Patients with Relapsed or High-Risk Multiple Myeloma BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. 2016.03; 22 (3): S228-S229. ( DOI )
Sasaki, K; Bashir, Q; Shah, N; Hosing, C; Popat, UR; Nieto, Y; Parmar, S; Shah, J; Weber, D; Thomas, S; Orlowski, RZ; Champlin, RE; Qazilbash, MH: Outcome of Patients with Multiple Myeloma by Ethnicity in the Setting of Autologous Stem Cell Transplant BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. 2016.03; 22 (3): S231-S232. ( DOI )
Koji Sasaki, Hagop M Kantarjian, Preetesh Jain, Elias J Jabbour, Farhad Ravandi, Marina Konopleva, Gautam Borthakur, Koichi Takahashi, Naveen Pemmaraju, Naval Daver, Sherry A Pierce, Susan M O'Brien, Jorge E Cortes: Conditional survival in patients with chronic myeloid leukemia in chronic phase in the era of tyrosine kinase inhibitors. Cancer. 2016.01; 122 (2): 238-248. ( PubMed , DOI )
Jacobs, RW; Saliba, RM; Sasaki, K; Farhan, S; Armas, A; Shah, ND; Bashir, Q; Qureshi, S; Rondon, G; Hosing, C; Popat, U; Parmar, S; Shah, JJ; Wang, M; Weber, DM; Thomas, SK; Orlowski, RZ; Champlin, RE; Qazilbashi, MH: Outcome of Patients With Nonsecretory Multiple Myeloma After Autologous Hematopoietic Stem Cell Transplantation CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2016.01; 16 (1): 36-42. ( PubMed , DOI )
Mari Kamiya, Peter Y Shane, Makoto Soejima, Shuji Tohda, Nobuyuki Miyasaka, Hitoshi Kohsaka: IgG4-Related Sialoadenitis with a Skin Lesion and Multiple Mononeuropathies Suggesting Coexistent Cryoglobulinemic Vasculitis. Intern. Med.. 2016; 55 (10): 1355-1361. ( PubMed , DOI )
Koji Sasaki, Sara S Strom, Susan O'Brien, Elias Jabbour, Farhad Ravandi, Marina Konopleva, Gautam Borthakur, Naveen Pemmaraju, Naval Daver, Preetesh Jain, Sherry Pierce, Hagop Kantarjian, Jorge E Cortes: Relative survival in patients with chronic-phase chronic myeloid leukaemia in the tyrosine-kinase inhibitor era: analysis of patient data from six prospective clinical trials. Lancet Haematol. 2015.05; 2 (5): e186-e193. ( PubMed , DOI )
Nogami Ayako, Oshikawa Gaku, Okada Keigo, Fukutake Shusaku, Umezawa Yoshihiro, Nagao Toshikage, Kurosu Tetsuya, Miura Osamu: FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia. Oncotarget. 2015.04; 6 (11): 9189-9205. ( PubMed )
Mitsuma S, Van den Bergh P, Rajabally YA, Van Parijs V, Martin-Lamb D, Sonoo M, Inaba A, Shimizu T, Isose S, Sato Y, Komori T, Misawa S, Kuwabara S, The Tokyo Metropolitan Neuromuscular Electrodiagnosis Study Group(including Kanouchi T): Effects of low frequency filtering on distal compound muscle action potential duration for diagnosis of CIDP: A Japanese-European multicenter prospective study. Clinical Neurophysiology. 2015; 126 1805-1810.
Saito R, Takahashi R, Sawabe E, Koyano S, Takahashi Y, Shima M, Ushizawa H, Fujie T, Tosaka N, Kato Y, Moriya K, Tohda S, Tojo N, Koike R, Kubota T: First Report of KPC-2 Carbapenemase-Producing Klebsiella pneumoniae in Japan. Antimicrob Agents Chemother. 2014.05; 58 (5): 2961-2963. ( PubMed , DOI )
Takebe I, Sawabe E, Ohkusu K, Tojo N, Tohda S: Catheter-related Bloodstream Infection by Tsukamurella inchonensis in an Immunocompromised Patient. J Clin Microbiol. 2014.03; 52 (6): 2251-2253. ( PubMed , DOI )
Mizuno N, Kanamori E, Saito H, Murakami N, Tojo N, Tohda S: A Case of Gray Platelet Syndrome Masked by Immune Thrombocytopenia at Presentation. Acta Haematol. 2014.02; 132 (2): 163-165. ( PubMed , DOI )
Teruhiko Sekiguchi, Tadashi Kanouchi, Kazumoto Shibuya, Yu-ichi Noto, Yohsuke Yagi, Akira Inaba, Keisuke Abe, Sonoko Misawa, Satoshi Orimo, Takayoshi Kobayashi, Tomoyuki Kamata, Masanori Nakagawa, Satoshi Kuwabara, Hidehiro Mizusawa, Takanori Yokota: Spreading of amyotrophic lateral sclerosis lesions--multifocal hits and local propagation? J. Neurol. Neurosurg. Psychiatr.. 2014.01; 85 (1): 85-91. ( PubMed , DOI )
Tohda S: NOTCH signaling roles in acute myeloid leukemia cell growth and interaction with other stemness-related signals. Anticancer Research. 2014; 34 (11): 6259-6264. ( PubMed )
Takahashi Y, Itoh M, Nara N, Tohda S: Effect of EPH-ephrin signaling on the growth of human leukemia cells. Anticancer Research. 2014; 34 2913-2918.
Nagao T, Kurosu T, Umezawa Y, Nogami A, Oshikawa G, Tohda S, Yamamoto M, Miura O: Proliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera. PLoS ONE. 2014; 9 (1): e84746. ( PubMed , DOI )
Okuhashi Y, Itoh M, Nara N, Tohda S: NOTCH knockdown affects the proliferation and mTOR signaling of leukemia cells. Anticancer Res. 2013.10; 33 (10): 4293-4298. ( PubMed )
Yonekura S, Itoh M, Okuhashi Y, Takahashi Y, Ono A, Nara N, Tohda S: Effects of the HIF1 inhibitor, echinomycin, on growth and NOTCH signalling in leukaemia cells. Anticancer Res. 2013.08; 33 (8): 3099-3103. ( PubMed )
Ono A, Oike R, Okuhashi Y, Takahashi Y, Itoh M, Nara N, Tohda S: Comparative effects of PP242 and rapamycin on mTOR signalling and NOTCH signalling in leukemia cells. Anticancer Research. 2013.03; 33 (3): 809-813. ( PubMed )
Kanamori E, Itoh M, Tojo N, Koyama T, Nara N, Tohda S: Flow cytometric analysis of Notch1 and Jagged1 expression in normal blood cells and leukemia cells. Exp Ther Med. 2012.09; 4 (3): 397-400. ( PubMed , DOI )
Ono A, Okuhashi Y, Takahashi Y, Itoh M, Nara N, Tohda S: Advantages of the quenching probe method over other PCR-based methods for detection of the JAK2 V617F mutation. Oncol Lett. 2012.08; 4 (2): 205-208. ( PubMed , DOI )
Takahashi Y, Ishigaki T, Okuhashi Y, Ono A, Itoh M, Nara N, Tohda S: Effect of BMP4 on the growth and clonogenicity of human leukemia and lymphoma cells. Anticancer Res. 2012.07; 32 (7): 2813-2817. ( PubMed )
Kanouchi Tadashi, Ohkubo Takuya, Yokota Takanori: Can regional spreading of amyotrophic lateral sclerosis motor symptoms be explained by prion-like propagation? J Neurol Neurosurg Psychiatry. 2012.07; 83 (7): 739-745. ( PubMed , DOI )
Kitamura Y, Sawabe E, Ohkusu K, Tojo N, Tohda S: First report of sepsis caused by Rhodococcus corynebacterioides in a patient with myelodysplastic syndrome. J Clin Microbiol. 2012.03; 50 (3): 1089-1091. ( PubMed , DOI )
Siegers GM, Dhamko H, Wang XH, Mathieson AM, Kosaka Y, Felizardo TC, Medin JA, Tohda S, Schueler J, Fisch P, Keating A: Human Vδ1 γδ T cells expanded from peripheral blood exhibit specific cytotoxicity against B-cell chronic lymphocytic leukemia-derived cells. Cytotherapy. 2011.07; 13 (6): 753-764. ( PubMed , DOI )
Kawaguchi-Ihara N, Okuhashi Y, Itoh M, Murohashi I, Nara N, Tohda S: Promotion of the self-renewal capacity of human leukemia cells by sonic hedgehog protein. Anticancer Res. 2011.03; 31 (3): 781-784. ( PubMed )
Okuhashi Y, Itoh M, Nara N, Tohda S: Effects of combination of notch inhibitor plus hedgehog inhibitor or Wnt inhibitor on growth of leukemia cells. Anticancer Res. 2011.03; 31 (3): 893-896. ( PubMed )
Nara N, Suzuki T, Tohda S: The current medical education system in the world. J Med Dent Sci. 2011; 58 (2): 79-83. ( PubMed )
Okuhashi Y, Itoh M, Arai A, Nara N, Tohda S: Gamma-secretase inhibitors induce erythroid differentiation in erythroid leukemia cell lines. Anticancer Res. 2010.10; 30 (10): 4071-4074. ( PubMed )
Ishigaki T, Sasaki K, Watanabe K, Nakamura N, Toyota S, Kobayashi H, Tohda S: Amplification of IGH/CCND1 fusion gene in a primary plasma cell leukemia case. Cancer Genet Cytogenet. 2010.08; 201 (1): 62-65. ( PubMed , DOI )
Okuhashi Y, Nara N, Tohda S: Effects of gamma-secretase inhibitors on the growth of leukemia cells. Anticancer Res. 2010.02; 30 (2): 495-498. ( PubMed )
Kawahara T, Kawaguchi-Ihara N, Okuhashi Y, Itoh M, Nara N, Tohda S: Cyclopamine and quercetin suppress the growth of leukemia and lymphoma cells. Anticancer Res. 2009.11; 29 (11): 4629-4632. ( PubMed )
Fu L, Katsube K, Tohda S: Transition of cleaved Notch1 and gene expression changes in myeloblastic leukemia cells stimulated with notch ligands. Anticancer Res. 2009.10; 29 (10): 3967-3970. ( PubMed )
Itoh M, Fu L, Tohda S: NF-kappaB activation induced by Notch ligand stimulation in acute myeloid leukemia cells. Oncol Rep. 2009.09; 22 (3): 631-634. ( PubMed )
Nara N, Beppu M, Tohda S, Suzuki T: The introduction and effectiveness of simulation-based learning in medical education. Intern Med. 2009; 48 (17): 1515-1519. ( PubMed )
Nemoto Y, Kanai T, Tohda S, Totsuka T, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Fukuda T, Miura O, Yagita H, Watanabe M: Negative feedback regulation of colitogenic CD4+ T cells by increased granulopoiesis. Inflamm Bowel Dis. 2008.11; 14 (11): 1491-1503. ( PubMed , DOI )
Kawaguchi-Ihara N, Murohashi I, Nara N, Tohda S: Promotion of the self-renewal capacity of human acute leukemia cells by Wnt3A. Anticancer Res. 2008.09; 28 (5A): 2701-2704. ( PubMed )
Kobayashi T, Terada Y, Kuwana H, Tanaka H, Okado T, Kuwahara M, Tohda S, Sakano S, Sasaki S: Expression and function of the Delta-1/Notch-2/Hes-1 pathway during experimental acute kidney injury. Kidney Int. 2008.06; 73 (11): 1240-1250. ( PubMed , DOI )
Morita-Hoshi Y, Tohda S, Miura O, Nara N: An autopsy case of multicentric Castleman's disease associated with interstitial nephritis and secondary AA amyloidosis. Int J Hematol. 2008.01; 87 (1): 69-74. ( PubMed , DOI )
Fu L, Nara N, Tohda S: Involvement of Notch signaling in myelodysplastic syndrome. Leuk Res. 2007.08; 31 (8): 1160-1161. ( PubMed , DOI )
Kogoshi H, Sato T, Koyama T, Nara N, Tohda S: Gamma-secretase inhibitors suppress the growth of leukemia and lymphoma cells. Oncol Rep. 2007.07; 18 (1): 77-80. ( PubMed )
Tohda S, Sato T, Kogoshi H, Fu L, Sakano S, Nara N: Establishment of a novel B-cell lymphoma cell line with suppressed growth by gamma-secretase inhibitors. Leuk Res. 2006.11; 30 (11): 1385-1390. ( PubMed , DOI )
Fu L, Kogoshi H, Nara N, Tohda S: NOTCH1 mutations are rare in acute myeloid leukemia. Leuk Lymphoma. 2006.11; 47 (11): 2400-2403. ( PubMed , DOI )
Kogoshi H, Tohda S, Fu L, Koyama T, Nara N: Effect of notch ligands on in vitro sensitivity to chemo-therapeutic drugs in leukemia and lymphoma cells. Oncol Rep. 2005.09; 14 (3): 723-726. ( PubMed )
Tohda S, Kogoshi H, Murakami N, Sakano S, Nara N: Diverse effects of the Notch ligands Jagged1 and Delta1 on the growth and differentiation of primary acute myeloblastic leukemia cells. Exp Hematol. 2005.05; 33 (5): 558-563. ( PubMed , DOI )
Murata-Ohsawa M, Tohda S, Kogoshi H, Sakano S, Nara N: The Notch ligand, Delta-1, alters retinoic acid (RA)-induced neutrophilic differentiation into monocytic and reduces RA-induced apoptosis in NB4 cells. Leuk Res. 2005.02; 29 (2): 197-203. ( PubMed , DOI )
Murata-Ohsawa M, Tohda S, Kogoshi H, Nara N: The Notch ligand, Delta-1, reduces TNF-alpha-induced growth suppression and apoptosis by decreasing activation of caspases in U937 cells. Int J Mol Med. 2004.11; 14 (5): 861-866. ( PubMed )
Murata-Ohsawa M, Tohda S, Nara N: Cellular analysis of growth suppression induced by the Notch ligands, Delta-1 and Jagged-1 in two myeloid leukemia cell lines. Int J Mol Med. 2004.08; 14 (2): 223-226. ( PubMed )
Murata-Ohsawa M, Tohda S, Sakano S, Nara N: The Notch ligand, Delta-1, partially inhibits GM-CSF-induced differentiation and apoptosis along with reducing the cleavage of PARP in U937 cells. Int J Mol Med. 2004.03; 13 (3): 419-423. ( PubMed )
Tohda S, Murata-Ohsawa M, Sakano S, Nara N: Notch ligands, Delta-1 and Delta-4 suppress the self-renewal capacity and long-term growth of two myeloblastic leukemia cell lines. Int J Oncol. 2003.05; 22 (5): 1073-1079. ( PubMed )
Tohda S, Sakano S, Ohsawa M, Murakami N, Nara N: A novel cell line derived from de novo acute myeloblastic leukaemia with trilineage myelodysplasia which proliferates in response to a Notch ligand, Delta-1 protein. Br J Haematol. 2002.05; 117 (2): 373-378. ( PubMed )
Tohda S, Murakami N, Nara N: Human herpesvirus 8 DNA in HIV-negative Japanese patients with multicentric Castleman's disease and related diseases. Int J Mol Med. 2001.11; 8 (5): 549-551. ( PubMed )
Tohda S, Nara N: Expression of Notch1 and Jagged1 proteins in acute myeloid leukemia cells. Leuk Lymphoma. 2001.07; 42 (3): 467-472. ( PubMed )
Tohda S, Ohkusa T: Resolution of refractory idiopathic thrombocytopenic purpura after eradication of Helicobacter pylori. Am J Hematol. 2000.12; 65 (4): 329-330. ( PubMed )
Tohda S, Murakami N, Nara N: Polymerase chain reaction detection of rearranged immunoglobulin heavy chain DNA in plasma samples is useful in the diagnosis of B-cell lymphoma. Int J Hematol. 2000.07; 72 (1): 74-78. ( PubMed )
Tohda S, Sakashita C, Fukuda T, Murakami N, Nara N: Establishment of a double Philadelphia chromosome-positive acute lymphoblastic leukemia-derived cell line, TMD5: effects of cytokines and differentiation inducers on growth of the cells. Leuk Res. 1999.03; 23 (3): 255-261. ( PubMed )
Tohda S, Koyama N, Tanaka M, Kida Y, Murakami N, Nara N: A case of atypical chronic myeloid leukemia regarded as MDS with myeloproliferative features. Acta Haematol. 1998; 100 (4): 191-194. ( PubMed )
Tohda S, Nara N: Phosphorylation of signaling proteins in factor-independent myeloid leukemia cell lines. Int J Oncol. 1997.10; 11 (4): 843-847. ( PubMed )
Tohda S, Maruyama M, Nara N: Molecular typing of methicillin-resistant Staphylococcus aureus by polymerase chain reaction: distribution of the typed strains in hospitals. Intern Med. 1997.10; 36 (10): 694-699. ( PubMed )
Nara N, Kurokawa H, Tohda S, Tomiyama J, Nagata K, Tanikawa S: Effect of vesnarinone, a quinolinone derivative, on the growth of leukemic blasts in acute myelogenous leukemia. Exp Hematol. 1997.03; 25 (3): 199-204. ( PubMed )
Imai Y, Yasuhara S, Hanafusa N, Ohsaka A, Enokihara H, Tomizuka H, Sonoyama M, Miura YS, Tohda S, Nara N, Takahashi A: Clonal involvement of eosinophils in therapy-related myelodysplastic syndrome with eosinophilia, translocation t(1;7) and lung cancer. Br J Haematol. 1996.12; 95 (4): 710-714. ( PubMed )
Tohda S, Kurokawa H, Nara N: Relation of protein kinase A and protein kinase C to signaling pathways of hematopoietic factors in leukemia cell lines. Int J Oncol. 1996.03; 8 (3): 521-524. ( PubMed )
Nara N, Kurokawa H, Tohda S, Tomiyama J, Nagata K, Tanikawa S: The effect of basic and acidic fibroblast growth factors (bFGF and aFGF) on the growth of leukemic blast progenitors in acute myelogenous leukemia. Exp Hematol. 1995.08; 23 (9): 1030-1034. ( PubMed )
Tohda S, Kurokawa H, Nara N: Diversity and similarity in signaling pathways of hematopoietic growth factors in human leukemia cell lines. Leukemia. 1995.05; 9 (5): 879-883. ( PubMed )
Koyama T, Hirosawa S, Kawamata N, Tohda S, Aoki N: All-trans retinoic acid upregulates thrombomodulin and downregulates tissue-factor expression in acute promyelocytic leukemia cells: distinct expression of thrombomodulin and tissue factor in human leukemic cells. Blood. 1994.11; 84 (9): 3001-3009. ( PubMed )
Tohda S, Shudo K, Minden M: The effects of retinoic Acid analogs on the blast cells of acute myeloblastic-leukemia in culture. Int J Oncol. 1994.06; 4 (6): 1311-1314. ( PubMed )
Tohda S, Minden MD: Modulation of growth factor receptors on acute myeloblastic leukemia cells by retinoic acid. Jpn J Cancer Res. 1994.04; 85 (4): 378-383. ( PubMed )
Nara N, Tohda S: Successful treatment of refractory pure red cell aplasia by buserelin acetate. Acta Haematol. 1994; 92 (1): 42-45. ( PubMed )
Tohda S, Ashman L, Minden M: The role of stroma cells on the proliferation and C-kit expression of acute myeloblastic-leukemia cells. Int J Oncol. 1993.12; 3 (6): 1141-1147. ( PubMed )
Murohashi I, Tohda S, Imai Y, Hirai Y, Nara N: Growth potentiating activity of endogenous production of interleukin-1 and tumor necrosis factor alpha in blast cells of acute myeloblastic leukemia. Exp Hematol. 1993.07; 21 (7): 846-851. ( PubMed )
Tohda S, Yang GS, Ashman LK, McCulloch EA, Minden MD: Relationship between c-Kit expression and proliferation in acute myeloblastic leukemia cell lines. J Cell Physiol. 1993.02; 154 (2): 410-418. ( PubMed , DOI )
Nara N, Chen GJ, Murohashi I, Tohda S, Imai Y, Tomiyama J, Nagata K, Suzuki T, Tanikawa S, Shiina S: The in vitro growth patterns and drug sensitivities of leukemic blast progenitors among the subtypes of acute myelocytic leukemia. Exp Hematol. 1992.08; 20 (7): 904-908. ( PubMed )
Tohda S, Curtis JE, McCulloch EA, Minden MD: Comparison of the effects of all-trans and cis-retinoic acid on the blast stem cells of acute myeloblastic leukemia in culture. Leukemia. 1992.07; 6 (7): 656-661. ( PubMed )
Kawamata N, Maruyama Y, Toda S, Takase K, Akiyama H, Sakamaki H, Onozawa Y: A case of chronic lymphocytic leukaemia with myeloid associated antigen. Br J Haematol. 1992.01; 80 (1): 129-130. ( PubMed )
Suzuki T, Bessho M, Hirashma K, Tohda S, Nagata K, Imai Y, Nara N: Interleukin-6 reduces the optimal growth in vitro of leukemic blast progenitors from acute myeloblastic leukemia patients. Acta Haematol. 1992; 87 (1-2): 63-68. ( PubMed )
Tohda S, Nara N, Tanikawa S, Imai Y, Murakami N, Aoki N: Pure red cell aplasia following autoimmune haemolytic anaemia. Cell-mediated suppression of erythropoiesis as a possible pathogenesis of pure red cell aplasia. Acta Haematol. 1992; 87 (1-2): 98-102. ( PubMed )
Suzuki T, Tohda S, Nagata K, Imai Y, Murohashi I, Nara N: Enhanced effect of mutant granulocyte-colony-stimulating factor (KW-2228) on the growth of normal and leukemic hemopoietic progenitor cells in comparison with recombinant human granulocyte-colony-stimulating factor (G-CSF). Acta Haematol. 1992; 87 (4): 181-189. ( PubMed )
Nara N, Tohda S, Suzuki T, Nagata K, Tanikawa S, Imai Y, Tomiyama J, Shiina S: Comparison of the proliferative activity and sensitivity to cytosine arabinoside of leukemic blast progenitors in acute myeloblastic leukemia at diagnosis and in relapse. Acta Haematol. 1992; 88 (1): 17-21. ( PubMed )
Tohda S, Minden MD, McCulloch EA: Interactions between retinoic acid and colony-stimulating factors affecting the blast cells of acute myeloblastic leukemia. Leukemia. 1991.11; 5 (11): 951-957. ( PubMed )
Tohda S, Nara N, Murohashi I, Aoki N: Establishment of an interleukin-3-dependent leukemic cell line from a patient with chronic lymphocytic leukemia in the acute phase. Blood. 1991.10; 78 (7): 1789-1794. ( PubMed )
Suzuki T, Bessho M, Hirashima K, Tohda S, Nagata K, Morio T, Imai Y, Nara N: Enhancement by transforming growth factor-beta 1 (TGF-beta 1) of the proliferation of leukemic blast progenitors stimulated with IL-3. J Cell Physiol. 1991.09; 148 (3): 396-403. ( PubMed , DOI )
Yamashita Y, Tohda S, Nagata K, Suzuki T, Imai Y, Nara N: The in vitro effect of vincristine on the blast cell renewal in acute myeloblastic leukemia. Jpn J Med. 1991.09; 30 (5): 412-419. ( PubMed )
Tohda S, Nara N, Imai Y, Aoki N: Effect of protein kinase inhibitors on the proliferation of leukemic cells stimulated by granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor or interleukin-3. Leukemia. 1991.09; 5 (9): 813-814. ( PubMed )
Imai Y, Nara N, Tohda S, Nagata K, Suzuki T, Nagasawa M, Murohashi I, Aoki N: Antiproliferative and differentiative effects of recombinant interleukin-4 on a granulocyte colony-stimulating factor-dependent myeloblastic leukemic cell line. Blood. 1991.07; 78 (2): 471-478. ( PubMed )
Imai Y, Tohda S, Nagata K, Suzuki T, Nara N, Aoki N: Effects of recombinant interleukin 4 on the growth and differentiation of blast progenitors stimulated with G-CSF, GM-CSF and IL-3 from acute myeloblastic leukaemia patients. Br J Haematol. 1991.06; 78 (2): 173-179. ( PubMed )
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Mizuno H, Nishida Y, Bedoy A, Ayoub E, Lee Y, Basi A, Sasaki K, Garcia-Manero G, Burks J, Kanagal-Shamanna R, Andreeff M: Niche-level immune evasion in TP53 mutant AML residual disease revealed by spatial proteomics 2026.05; ( DOI )
Changrong Duan, Zhiqian Yu, Xue Li, Mai Sakai, Yuko Maejima, Kenju Shimomura, Tomoyuki Furuyashiki, Saya Kikuchi, Natsuko Kobayashi, Kazuto Sasaki, Tasuku Matsuki, Hiroshi Komatsu, Mizuki Hino, Yasuto Kunii, Tomoko Kasahara, Mami Ishikuro, Keiko Murakami, Masatsugu Orui, Takaaki Abe, Fuji Nagami, Nobuo Fuse, Soichi Ogishima, Kengo Kinoshita, Masayuki Yamamoto, Naoki Nakaya, Atsushi Hozawa, Taku Obara, Shinichi Kuriyama, Hiroaki Tomita: Sex differences in the risk of autistic-related traits in toddlers born to mothers with perinatal depression: Evidence from human cohort and mouse study Molecular Psychiatry. 2026.02; ( PubMed , DOI )
Samuel Urrutia, Koji Sasaki, Alex Bataller, Hagop Kantarjian, Guillermo Montalban-Bravo, James McCloskey, Elizabeth A. Griffiths, Karen Yee, Amer Zeidan, Michael Savona, Aram Oganesian, Yuri Sano, Harold N. Keer, Guillermo Garcia-Manero: Decitabine-cedazuridine in patients with MDS and TP53 mutations Blood Advances. 2026.02; 10 (3): ( DOI )
Nicholas J. Short, Hagop Kantarjian, Nitin Jain, Tapan M. Kadia, Jayastu Senapati, Fadi G. Haddad, Manuel M. Maroun, Koji Sasaki, Lianchun Xiao, Xuelin Huang, Omer Karrar, Regina Abramova, Min Zhao, Rebecca Garris, Marina Konopleva, Farhad Ravandi, Elias Jabbour: Mini-hyper-CVD plus venetoclax and navitoclax for relapsed/refractory acute lymphoblastic leukemia Blood Advances. 2026.01; 10 (1): ( DOI )
Wei‐Ying Jen, Guilin Tang, Eitan Kugler, Jennifer Croden, Koji Sasaki, Alexandre Bazinet, Alex Bataller, Guillermo Montalban‐Bravo, Gautam Borthakur, Gokce A. Toruner, Sanam Loghavi, Nicholas J. Short, Ghayas C. Issa, Ian M. Bouligny, Sherry Pierce, Uday Popat, Naveen Pemmaraju, Elias Jabbour, Guillermo Garcia‐Manero, Kapil Bhalla, Farhad Ravandi, Naval G. Daver, Courtney D. DiNardo, Hagop M. Kantarjian, Tapan M. Kadia: MECOM fusion partner and bone marrow blast percentage influence outcomes of patients with MECOM rearranged acute myeloid leukaemia British Journal of Haematology. 2025.12; ( DOI )
Samuel Urrutia, Wei-Ying Jen, Koji Sasaki, Peter H. Wiernik, Tapan Kadia, Naval Daver, Courtney D. DiNardo, Guillermo Garcia-Manero, Elias Jabbour, Nicholas J. Short, Ghayas Issa, Farhad Ravandi, Musa Yilmaz: Mortality and relapse dynamics in AML after three years of complete remission Leukemia & Lymphoma. 2025.11; ( DOI )
Alexandre Bazinet, Guillermo Montalban-Bravo, Alex Bataller, Danielle Hammond, Sanam Loghavi, Kelly Chien, Koji Sasaki, Ian Bouligny, Mahesh Swaminathan, Wei Ying Jen, Uday Popat, Tapan Kadia, Courtney DiNardo, Elias Jabbour, Nicholas Short, Naval Daver, Farhad Ravandi, Guillermo Garcia-Manero: Impact of discordant revised versus molecular international prognostic scoring system risk in myelodysplastic syndrome Leukemia. 2025.11; ( DOI )
Reeja Raj, Samanta Catueno, Amber Gibson, David McCall, Miriam B. Garcia, César Nunez, Michael Roth, Koji Sasaki, Priti Tewari, Ghayas C. Issa, Aziz Farhat, Jeremy Connors, Irtiza Sheikh, Yuki Nishida, Joanna S. Yi, Alexandra M. Stevens, Alex Bataller, Kapil Bhalla, Demetrios Petropoulos, Naval Daver, Tapan Kadia, Branko Cuglievan, Courtney D. DiNardo: FLAG-IDA plus venetoclax for children, adolescents, and young adults with newly diagnosed AML Blood. 2025.11; 146 (21): ( DOI )
Omer Karrar, Hagop Kantarjian, Fadi G. Haddad, Roberta S. Azevedo, Ghayas Issa, Farhad Ravandi, Koji Sasaki, Jayastu Senapati, Hussein Abbas, Sara Dellasala, Elias Jabbour, Nicholas J. Short: Outcomes and patterns of relapse with ponatinib-based therapy in patients with chronic myeloid leukemia in myeloid blast phase Leukemia & Lymphoma. 2025.10; ( DOI )
Mehmet Sevki Uyanik, Elias Jabbour, Nicholas Short, Koji Sasaki, Shilpa Paul, Guillermo Garcia-Manero, Tapan Kadia, Farhad Ravandi, Nitin Jain: Nelarabine-related rhabdomyolysis in adult patients with T-cell lymphoblastic leukemia/lymphoma: a report of 6 patients Leukemia & Lymphoma. 2025.09; ( DOI )
Alexandre Bazinet, Sanam Loghavi, Yue Wei, Alex Bataller, Koji Sasaki, Naszrin Arani, Faezeh Darbaniyan, Kelly Chien, Danielle Hammond, Ian Bouligny, Rashmi Kanagal-Shamanna, Natthakan Thongon, Guilin Tang, Samuel Urrutia, Tapan Kadia, Courtney DiNardo, Naval Daver, Nicholas Short, Ghayas Issa, Naveen Pemmaraju, Elias Jabbour, Sa A. Wang, Wei Wang, Gautam Borthakur, Carlos Bueso-Ramos, Farhad Ravandi, L. Jeffrey Medeiros, Hagop Kantarjian, Guillermo Garcia-Manero, Guillermo Montalban-Bravo: Erythroid-predominant myelodysplastic neoplasms exhibit a distinct genomic landscape with poor outcomes after venetoclax-based therapy Leukemia. 2025.09; ( DOI )
Courtney D. DiNardo, Jennifer Marvin-Peek, Sanam Loghavi, Koichi Takahashi, Ghayas C. Issa, Wei-Ying Jen, Naval G. Daver, Patrick K. Reville, Nicholas J. Short, Koji Sasaki, Jillian K. Mullin, Corey A. Bradley, Gautam Borthakur, Abhishek Maiti, Yesid Alvarado, Naveen Pemmaraju, Hussein A. Abbas, Danielle E. Hammond, Fadi Haddad, Guillermo Montalban Bravo, Kelly S. Chien, Musa Yilmaz, Steven M. Kornblau, Elias Jabbour, Farhad Ravandi, Tapan Kadia, Guillermo Garcia-Manero, Marina Y. Konopleva, Hagop M. Kantarjian: Outcomes of Frontline Triplet Regimens With a Hypomethylating Agent, Venetoclax, and Isocitrate Dehydrogenase Inhibitor for Intensive Chemotherapy–Ineligible Patients With Isocitrate Dehydrogenase–Mutated AML Journal of Clinical Oncology. 2025.08; ( DOI )
Haddad FG, Croden J, Sasaki K, Issa GC, Pemmaraju N, Kantarjian H, Jabbour E: Management of Chronic Myeloid Leukemia During Pregnancy: Review of Evidence and Treatment Algorithm. Clinical lymphoma, myeloma & leukemia. 2025.08; 26 (1): ( PubMed , DOI )
Croden J, Jen WY, Marvin-Peek J, Xiao L, Bouligny IM, Loghavi S, Borthakur G, Daver NG, Abbas HA, Takahashi K, Sasaki K, Pemmaraju N, Short NJ, DiNardo CD: Outcomes of adult patients with newly diagnosed IDH-mutated AML treated with intensive chemotherapy and venetoclax. Leukemia. 2025.08; ( PubMed , DOI )
Roberta S. Azevedo, Luis Fayad, Rashmi Kanagal-Shamanna, Sanam Loghavi, Shimin Hu, Carlos E. Bueso-Ramos, Koji Sasaki, Tareq Abuasab, Fareed Khawaja, Hannah Goulart, Iman Abou Dalle, Gautam Borthakur, Naveen Pemmaraju: Treatment of RAS-associated leukoproliferative disease (RALD) and Rosai-Dorfman disease in a patient with KRAS mutation Leukemia & Lymphoma. 2025.08; ( DOI )
Montalban-Bravo G, Loghavi S, Li Z, Chien KS, Kanagal-Shamanna R, Bataller A, Natu A, Gurney M, Bazinet A, Hammond D, Sasaki K, Borthakur G, Patnaik MM: Landscape and clinicopathologic features of RAS pathway mutations in chronic myelomonocytic leukemia. Blood advances. 2025.07; 9 (19): ( PubMed , DOI )
Hagop Kantarjian, Massimo Breccia, Fadi G. Haddad, Rüdiger Hehlmann, Ghayas C. Issa, Hemant Malhotra, Franck Emmanuel Nicolini, Koji Sasaki, Leif Stenke, Elias Jabbour: Management of chronic myeloid leukemia in 2025 Cancer. 2025.07; ( DOI )
J. Wesley Hill, Jennifer Marvin-Peek, Koji Sasaki, Sara Bresser, Bouthaina Shbib Dabaja, Nitin Jain, Gautam Borthakur, Hussein A. Abbas: Central nervous system relapse of core-binding factor acute myeloid leukemia Leukemia & Lymphoma. 2025.07; ( DOI )
Bazinet A, Bataller A, Montalban-Bravo G, Chien K, Sasaki K, Jen WY, Swaminathan M, Kadia T, DiNardo C, Ravandi F, Garcia-Manero G, Kantarjian H: PTPN11 mutations define a rare but highly adverse subset of myelodysplastic syndromes. Haematologica. 2025.07; 110 (12): ( PubMed , DOI )
Azevedo RS, Jen WY, Hammond D, Haddad FG, Geppner A, Issa GC, Sasaki K, Senapati J, Jabbour E, Ravandi F, Kantarjian H, Kadia TM: Lower-intensity chemo-immunotherapy with cladribine, low-dose cytarabine, venetoclax and blinatumomab produces high response rates in patients with <i>BCR::ABL1</i>-negative B-cell / myeloid mixed phenotype acute leukemia. Haematologica. 2025.06; 110 (12): ( PubMed , DOI )
Csizmar CM, Natu A, Gurney M, Fathima S, Alsugair AKA, Kanagal-Shamanna R, Loghavi S, Bazinet A, Chien K, Hammond D, DiNardo C, Kadia T, Patnaik MM: Multiple TET2 mutations confer additional survival benefit in both myelodysplastic and myeloproliferative chronic myelomonocytic leukemia subtypes. Leukemia. 2025.06; ( PubMed , DOI )
Edelman Saul E, Urrutia S, Yang H, Montalban-Bravo G, Tang G, Toruner G, Patel K, Luthra R, Bueso-Ramos C, Wang SA, Chien K, Sasaki K, Atluri H, Kanagal-Shamanna R: A Case of Cryptic CBFB::MYH11 Acute Myeloid Leukemia With Noncanonical Breakpoints Detected by Optical Genome Mapping. Journal of the National Comprehensive Cancer Network : JNCCN. 2025.05; ( PubMed , DOI )
Andreas Hochhaus, Dong-Wook Kim, Jorge E. Cortes, Koji Sasaki, Michael J. Mauro, Timothy P. Hughes, Massimo Breccia, Moshe Talpaz, Hironobu Minami, Yeow Tee Goh, Daniel J. DeAngelo, Fabian Lang, Oliver Ottmann, Michael C. Heinrich, Valle Gomez Garcia de Soria, Philipp le Coutre, Gessami Sanchez-Olle, Meng Cao, Nathalie Pognan, Shruti Kapoor, Matthias Hoch, Delphine Rea: Asciminib monotherapy in patients with chronic myeloid leukemia in chronic phase without BCR::ABL1T315I treated with at least 2 prior TKIs: Phase 1 final results Leukemia. 2025.05; ( DOI )
Mauro MJ, Minami Y, Hochhaus A, Lomaia E, Voloshin S, Turkina A, Kim DW, Apperley JF, Cortes J, Abdo A, Fogliato LM, Kim DDH, le Coutre P, Rea D: Asciminib remained superior vs bosutinib in late-line CML-CP after nearly 4 years of follow-up in ASCEMBL. Blood advances. 2025.05; 9 (16): ( PubMed , DOI )
Tefferi A, Fathima S, Abdelmagid M, Alsugair A, Aperna F, Rezasoltani M, Yousuf M, Natu A, Csizmar CM, Gurney M, Lasho TL, Finke CM, Patnaik MM: BLAST: A Globally Applicable and Molecularly Versatile Survival Model for Chronic Myelomonocytic Leukemia. Blood. 2025.05; 146 (7): ( PubMed , DOI )
Bataller A, Goulart HE, Issa GC, DiNardo CD, Daver N, Kadia T, Bazinet A, Bouligny IM, Senapati J, Haddad FG, Borthakur G, Sasaki K, Short NJ, Jabbour E: Characteristics and outcomes of newly diagnosed acute myeloid Leukemia with KMT2A rearrangements. Leukemia. 2025.05; ( PubMed , DOI )
Hagop Kantarjian, Yifan Zhai, Vivian G. Oehler, Omer Jamy, Paul B. Koller, Fadi G. Haddad, Koji Sasaki, Elias J. Jabbour: Olverembatinib in chronic myeloid leukemia—Review of historical development, current status, and future research Cancer. 2025.04; ( DOI )
Cortes, J.E., Lang, F., Rea, D., Hochhaus, A., Breccia, M., Goh, Y.T., Heinrich, M.C., Hughes, T.P., Janssen, J.J.W.M., le Coutre, P., Minami, H., Sasaki, K., DeAngelo, D.J., Sanchez-Olle, G., Pognan, N., Cao, M., Hoch, M., Mauro, M.J.: Asciminib in combination with imatinib, nilotinib, or dasatinib in patients with chronic myeloid leukemia in chronic or accelerated phase: phase 1 study final results: CHRONIC MYELOID LEUKEMIA Leukemia. 2025.04; ( DOI )
Daver N, Senapati J, Kantarjian HM, Wang B, Reville PK, Loghavi S, Yilmaz M, DiNardo CD, Kadia TM, Yassouf MY, Maiti A, Arora S, Montalban Bravo G, Abbas HA: Azacitidine, Venetoclax and Magrolimab in Newly Diagnosed and Relapsed Refractory Acute Myeloid Leukemia: Phase 1b/2 Study and Correlative Analysis. Clinical cancer research : an official journal of the American Association for Cancer Research. 2025.04; ( PubMed , DOI )
Nishida Y, Impedovo V, Ayoub E, Baran N, Scruggs DA, Mizuno H, Khazaei S, Ostermann LB, Singh S, Bedoy A, Mak PY, Carter BZ, Sugihara E, Takimoto T, Andreeff M: Dual MYC and GSPT1 Protein Degrader for MYC-Driven Cancers 2025.04; ( DOI )
Silbert SK, Rankin AW, Hoang CN, Semchenkova A, Myers RM, Zerkalenkova E, Wang HW, Kovach AE, Yuan CM, Delgado Colon D, Vasseur L, Bataller A, Shah NN: Project EVOLVE: An international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia. Blood. 2025.04; ( PubMed , DOI )
Willekens C, Bazinet A, Chraibi S, Bataller A, Decroocq J, Arani N, Carpentier B, Rausch C, Lebon D, Maiti A, Gauthier N, Short N, Bonnet S, DiNardo C: Reduced venetoclax exposure to 7 days vs standard exposure with hypomethylating agents in newly diagnosed AML patients. Blood cancer journal. 2025.04; 15 (1): ( PubMed , DOI )
Braish JS, Montalban-Bravo G, Ravandi F, Short N, Kadia T, Ohanian M, Chien K, Masarova L, Sasaki K, Yilmaz M, Logahvi S, Daver N, Borthakur G, Garcia-Manero G: Safety and efficacy of the combination of azacitidine with venetoclax after hypomethylating agent failure in higher-risk myelodysplastic syndrome. Leukemia research. 2025.04; 153 ( PubMed , DOI )
Chien KS, Braish JS, Li Z, Loghavi S, Bataller A, Montalban-Bravo G, Sasaki K, Kanagal-Shamanna R, Takahashi K, DiNardo CD, Swaminathan M, Garcia-Manero G: Clinicopathologic characteristics and outcomes of patients with clonal hematopoiesis who progress to myeloid neoplasms. Leukemia. 2025.04; ( PubMed , DOI )
Habib D, Jabbour E, Bataller A, Sasaki K, Tang G, Loghavi S, Li S, Senapati J, Short NJ, Jain N, Kantarjian H, Haddad FG: Inferior Outcomes in Acute Lymphoblastic Leukemia With Translocation (14;18). Clinical lymphoma, myeloma & leukemia. 2025.03; ( PubMed , DOI )
Kugler E, Dasdemir E, Bataller A, Wang B, DiNardo CD, Daver N, Yilmaz M, Short NJ, Borthakur G, Kadia TM, Sasaki K, Hammond D, Bazinet A, Irajizad E, Abbas HA: Mutation dynamics from diagnosis to relapse in acute myeloid leukemia with chromosomal 7 deletions. Leukemia & lymphoma. 2025.03; ( PubMed , DOI )
Alexandre Bazinet, Alex Bataller, Tapan Kadia, Naval Daver, Nicholas J. Short, Musa Yilmaz, Koji Sasaki, Courtney D. DiNardo, Gautam M. Borthakur, Ghayas Issa, Ian Bouligny, Sherry Pierce, Guillermo Garcia‐Manero, Farhad Ravandi, Hagop M. Kantarjian: A retrospective study of outcomes across time and treatment regimens in newly diagnosed, FMS‐like tyrosine kinase 3 (FLT3)‐mutated acute myeloid leukemia Cancer. 2025.03; ( DOI )
Eitan Kugler, Hagop Kantarjian, Elias Jabbour, Niranjan Khaire, Nicholas J. Short, Tapan M. Kadia, Fadi G. Haddad, Koji Sasaki, Rashmi Kanagal Shamanna, Rebecca Garris, Farhad Ravandi, Nitin Jain: Treatment‐free remission in nontransplanted patients with Philadelphia chromosome‐positive acute lymphoblastic leukemia Cancer. 2025.03; ( DOI )
Fiskus W, Mill CP, Piel J, Collins M, Hentemann M, Cuglievan B, Birdwell CE, Das K, Hou H, Davis JA, Jain A, Malovannaya A, Kadia TM, Daver N, Bhalla KN: Superior preclinical efficacy of co-treatment with BRG1/BRM and FLT3 inhibitor against AML cells with FLT3 mutations. Blood cancer journal. 2025.03; ( PubMed , DOI )
Alex Bataller, Koji Sasaki, Samuel Urrutia, Guillermo Montalban-Bravo, Alexandre Bazinet, Kelly Chien, Danielle Hammond, Ian M. Bouligny, Mahesh Swaminathan, Ghayas Issa, Nicholas Short, Naval Daver, Courtney D. DiNardo, Tapan Kadia, Elias Jabbour, Farhad Ravandi, Gail J. Roboz, Michael Savona, Elizabeth A. Griffiths, James McCloskey, Olatoyosi Odenike, Aram Oganesian, Harold N. Keer, Mohammad Azab, Hagop Kantarjian, Guillermo Garcia-Manero: Oral decitabine cedazuridine with and without venetoclax in higher-risk myelodysplastic syndromes or chronic myelomonocytic leukemia: a propensity score–matched study Blood Cancer Journal. 2025.03; 15 (1): ( DOI )
DiNardo CD, Jen WY, Takahashi K, Kadia TM, Loghavi S, Daver NG, Xiao L, Reville PK, Issa GC, Short NJ, Sasaki K, Wang SA, Mullin JK, Pierce S, Kantarjian HM: Long term results of venetoclax combined with FLAG-IDA induction and consolidation for newly diagnosed and relapsed or refractory acute myeloid leukemia. Leukemia. 2025.02; ( PubMed , DOI )
Ian M. Bouligny, Guillermo Montalban-Bravo, Koji Sasaki, Naval Daver, Elias Jabbour, Yesid Alvarado, Courtney D. DiNardo, Farhad Ravandi, Gautam Borthakur, Naveen Pemmaraju, Tapan Kadia, Lucia Masarova, Koichi Takahashi, Michael Andreeff, Alexandre Bazinet, Hui Yang, Rashmi Kanagal, Sherry Pierce, Meghan Meyer, Xuelin Huang, Guillermo Garcia-Manero: A phase II trial of ipilimumab, nivolumab, or ipilimumab and nivolumab with or without azacitidine in relapsed or refractory myelodysplastic neoplasms Leukemia. 2025.02; 39 (2): 524-528. ( PubMed , DOI )
Wei-Ying Jen, Koji Sasaki, Farhad Ravandi, Tapan M. Kadia, Sa A. Wang, Wei Wang, Sanam Loghavi, Naval G. Daver, Courtney D. DiNardo, Ghayas C. Issa, Hussein A. Abbas, Cedric Nasnas, Alex Bataller, Samuel Urrutia, Omer S. Karrar, Sherry Pierce, Hagop M. Kantarjian, Nicholas J. Short: Impact of measurable residual disease clearance kinetics in patients with AML undergoing intensive chemotherapy Blood Advances. 2025.02; ( DOI )
Takaoka K, Komrokji R, Chien K, Montalban-Bravo G, Salman JB, Urrutia S, Bataller A, Bazinet A, Kekedjian J, Al Ali NH, Sallman D, Padron E, Xie Z, Sasaki K: Characteristics and survival outcomes of patients with myelodysplastic syndromes with isolated 11q deletion. Leukemia research. 2025.02; 150 ( PubMed , DOI )
Koji Sasaki: Favorable transplantation outcome of patients with de novo chronic myeloid leukemia in blast phase (lymphoid and myeloid) Cancer. 2025.01; 131 (1): ( PubMed , DOI )
Kantarjian H, Short NJ, Jain N, Haddad FG, Kadia T, Yilmaz M, Ferrajoli A, Sasaki K, Alvarado Y, Pemmaraju N, Senapati J, Garris R, Ravandi F, Jabbour E: Hyper-CVAD and Sequential Blinatumomab Without and With Inotuzumab in Young Adults With Newly Diagnosed Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia. American journal of hematology. 2025.01; 100 (3): 402-407. ( PubMed , DOI )
Koji Sasaki: Novel therapeutic strategies targeting MECOM rearranged AMLs discovered by unbiased drug screen CANCER RESEARCH. 2025; ( DOI )
Koji Sasaki: ASXL1 mutations in AML are associated with a distinct epigenetic state that results in vulnerabilities to epigenetic-targeted agents CANCER RESEARCH. 2025; ( DOI )
Koji Sasaki: Blood-based proteomic profiling identifies OSMR as a novel biomarker of AML outcomes BLOOD. 2025; ( DOI )
Urrutia S, Kantarjian HM, Ravandi-Kashani F, Bueso-Ramos C, Kanagal-Shamanna R, Jabbour E, Montalban-Bravo G, Short NJ, Daver N, Borthakur G, Sasaki K: Outcomes of patients with acute myeloid leukemia and bone marrow fibrosis. Journal of hematology & oncology. 2024.11; 17 (1): ( PubMed , DOI )
Jen WY, Marvin-Peek J, Kantarjian HM, Alvarado Y, Borthakur G, Jabbour E, Wierda W, Kadia TM, Daver NG, DiNardo CD, Short NJ, Jain N, Ferrajoli A, Ravandi F: Long-term follow-up of a phase 2 study of all-trans retinoic acid, arsenic trioxide, and gemtuzumab ozogamicin in acute promyelocytic leukemia. Cancer. 2024.11; 131 (1): ( PubMed , DOI )
Koji Sasaki, Guillermo Garcia-Manero, Masayuki Nigo, Elias Jabbour, Farhad Ravandi, William G. Wierda, Nitin Jain, Koichi Takahashi, Guillermo Montalban-Bravo, Naval G. Daver, Philip A. Thompson, Naveen Pemmaraju, Dimitrios P. Kontoyiannis, Junya Sato, Sam Karimaghaei, Kelly A. Soltysiak, Issam I. Raad, Hagop M. Kantarjian, Brett W. Carter: Artificial Intelligence Assessment of Chest Radiographs for COVID-19 Clinical Lymphoma Myeloma and Leukemia. 2024.11; ( DOI )
Haddad FG, Sasaki K, Senapati J, Hu S, Dellasala S, Issa GC, Jabbour E, Kantarjian H: Successful Treatment-Free Remission After Ponatinib Discontinuation in Pretreated Patients with Chronic Myeloid Leukemia in Chronic Phase. Clinical lymphoma, myeloma & leukemia. 2024.11; 25 (4): 254-257. ( PubMed , DOI )
Hagop Kantarjian, Gautam Borthakur, Naval Daver, Courtney D. DiNardo, Ghayas Issa, Elias Jabbour, Tapan Kadia, Koji Sasaki, Nicholas J. Short, Musa Yilmaz, Farhad Ravandi: Current status and research directions in acute myeloid leukemia Blood Cancer Journal. 2024.09; 14 (1): ( PubMed , DOI )
Cuglievan B, Kantarjian H, Rubnitz JE, Cooper TM, Zwaan CM, Pollard JA, DiNardo CD, Kadia TM, Guest E, Short NJ, McCall D, Daver N, Nunez C, Issa GC: Menin inhibitors in pediatric acute leukemia: a comprehensive review and recommendations to accelerate progress in collaboration with adult leukemia and the international community. Leukemia. 2024.08; 38 (10): 2073-2084. ( PubMed , DOI )
McCall D, Abuasab T, Rodriguez-Sevilla JJ, Mohamed SF, Patnaik A, Devireddy K, Arani N, Sheikh I, Jamshidi R, Gibson A, Roth M, Nuñez C, Garcia M, Garcia-Manero G: Characteristics and outcomes of children, adolescent, and young adult patients with myelodysplastic neoplasms: A single-center retrospective analysis. Leukemia research. 2024.08; 144 ( PubMed , DOI )
Braish JS, Kugler E, Jabbour E, Woodman K, Ravandi F, Nicholas S, Jain N, Kantarjian H, Sasaki K: Incidence and Clinical Presentation of Severe Neurotoxicity from Nelarabine in Patients with T-Cell Acute Lymphoblastic Leukemia. Clinical lymphoma, myeloma & leukemia. 2024.06; 24 (11): 783-788. ( PubMed , DOI )
Gener-Ricos, G., Bataller, A., Rodriguez-Sevilla, J.J., Chien, K.S., Quesada, A.E., Almanza-Huante, E., Hammond, D., Sasaki, K., DiNardo, C., Kadia, T., Daver, N., Borthakur, G., Issa, G.C., Short, N.J., Kanagal-Shamanna, R., Kantarjian, H.M., Garcia-Manero, G., Montalban-Bravo, G.: NPM1-mutated myeloid neoplasms are a unique entity not defined by bone marrow blast percentage Cancer. 2024.06; 130 (20): 3452-3462. ( PubMed , DOI )
Ali, M.A., Aiman, W., Kantarjian, H., Jabbour, E., Ravandi, F., Jain, N., Short, N.J., Sasaki, K.: Efficacy of Chemotherapy-Free Regimens in the Treatment of Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: A Systematic Review and Meta-Analysis Clinical Lymphoma, Myeloma and Leukemia. 2024.06; 24 (10): e376-e384. ( PubMed , DOI )
Fadi G. Haddad, Koji Sasaki, Ghayas C. Issa, Elias Jabbour, Hagop Kantarjian: The presence of additional cytogenetic abnormalities (ACAs) or Philadelphia chromosome variants do not adversely affect the achievement of treatment‐free remission in chronic myeloid leukemia American Journal of Hematology. 2024.06; 99 (6): 1175-1176. ( PubMed , DOI )
Koji Sasaki: TP53 Y220C mutations in patients with myeloid malignancies (vol 10, pg 1, 2024) Leukemia & Lymphoma. 2024.06; 65 (10): 1511-1515. ( PubMed , DOI )
Jorge E. Cortes, Koji Sasaki, Dong-Wook Kim, Timothy P. Hughes, Gabriel Etienne, Michael J. Mauro, Andreas Hochhaus, Fabian Lang, Michael C. Heinrich, Massimo Breccia, Michael Deininger, Yeow Tee Goh, Jeroen J.W.M. Janssen, Moshe Talpaz, Valle Gomez Garcia de Soria, Philipp le Coutre, Daniel J. DeAngelo, Andrea Damon, Silvia Cacciatore, Fotis Polydoros, Nithya Agrawal, Delphine Rea: Asciminib monotherapy in patients with chronic-phase chronic myeloid leukemia with the T315I mutation after ≥1 prior tyrosine kinase inhibitor: 2-year follow-up results Leukemia. 2024.05; 38 (7): 1522-1533. ( PubMed , DOI )
Bataller, A., Kantarjian, H., Bazinet, A., Kadia, T., Daver, N., DiNardo, C.D., Borthakur, G., Loghavi, S., Patel, K., Tang, G., Sasaki, K., Short, N.J., Yilmaz, M., Issa, G.C., Alvarado, Y., Montalban-Bravo, G., Maiti, A., Abbas, H.A., Takahashi, K., Pierce, S., Jabbour, E., Garcia-Manero, G., Ravandi, F.: Outcomes and genetic dynamics of acute myeloid leukemia at first relapse Haematologica. 2024.05; 109 (11): 3543-3556. ( PubMed , DOI )
Jabbour, Elias, Haddad, Fadi G, Sasaki, Koji, Carter, Bing Z, Alvarado, Yesid, Nasnas, Cedric, Nasr, Lewis, Masarova, Lucia, Daver, Naval, Pemmaraju, Naveen, others: Combination of dasatinib and venetoclax in newly diagnosed chronic phase chronic myeloid leukemia Cancer. 2024.04; 130 (15): 2652-2659. ( PubMed , DOI )
Jen, Wei-Ying, Sasaki, Koji, Loghavi, Sanam, Wang, Sa A, Qiao, Wei, Borthakur, Gautam, Ravandi, Farhad, Kadia, Tapan M, Issa, Ghayas C, Short, Nicholas J, others: Characteristics and outcomes of acute myeloid leukaemia patients with baseline CD7 expression British Journal of Haematology. 2024.04; 204 (6): 2259-2263. ( PubMed , DOI )
Short, Nicholas J, Jabbour, Elias, Nasr, Lewis F, Jain, Nitin, Haddad, Fadi G, Issa, Ghayas C, Sasaki, Koji, Senapati, Jayastu, Kebriaei, Partow, Garris, Rebecca, others: Characteristics and outcomes of patients with relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia after failure of a frontline ponatinib-containing therapy American journal of hematology. 2024.04; 99 (7): 1423-1426. ( PubMed , DOI )
Bazinet, Alexandre, Kantarjian, Hagop, Bataller, Alex, Pemmaraju, Naveen, Borthakur, Gautam, Chien, Kelly, Alvarado, Yesid, Bose, Prithviraj, Jabbour, Elias, Yilmaz, Musa, others: Reduced dose azacitidine plus venetoclax as maintenance therapy in acute myeloid leukaemia following intensive or low-intensity induction: a single-centre, single-arm, phase 2 trial The Lancet Haematology. 2024.04; 11 (4): e287-e298. ( PubMed , DOI )
Kantarjian, Hagop, Branford, Susan, Breccia, Massimo, Cortes, Jorge, Haddad, Fadi G, Hochhaus, Andreas, Hughes, Timothy, Issa, Ghayas C, Jabbour, Elias, Nicolini, Franck E, others: Are there new relevant therapeutic endpoints in the modern era of the BCR:: ABL1 tyrosine kinase inhibitors in chronic myeloid leukemia? Leukemia. 2024.03; 38 (5): 1-4. ( PubMed , DOI )
Bataller, A., Gener-Ricos, G., Almanza-Huante, E., Chien, K.S., Urrutia, S., Bazinet, A., Rodriguez-Sevilla, J.J., Hammond, D., Sasaki, K., Takahashi, K., DiNardo, C.D., Ravandi, F., Borthakur, G., Kadia, T.M., Kanagal-Shamanna, R., Kantarjian, H.M., Garcia-Manero, G., Montalban-Bravo, G.: Therapy-related chronic myelomonocytic leukemia does not have the high-risk features of a therapy-related neoplasm Blood Advances. 2024.03; 8 (11): 2695-2706. ( PubMed , DOI )
Sasaki, Koji, Ravandi, Farhad, Kadia, Tapan, DiNardo, Courtney D, Yilmaz, Musa, Short, Nicholas, Jabbour, Elias, Patel, Keyur P, Loghavi, Sanam, Pierce, Sherry, others: Outcome of Patients with Relapsed Acute Promyelocytic Leukemia Clinical Lymphoma Myeloma and Leukemia. 2024.02; 24 (6): 375-381. ( PubMed , DOI )
Fiskus, Warren, Piel, Jessica, Collins, Michael P, Hentemann, Murphy, Cuglievan, Branko, Mill, Christopher P, Birdwell, Christine, Das, Kaberi, Davis, John A, Hou, Hanxi, others: BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or Menin inhibitor Blood Journal. 2024.02; 143 (20): blood-2023022832. ( PubMed , DOI )
Haddad, Fadi G, Nasnas, Cedric, Sasaki, Koji, Paul, Shilpa, Issa, Ghayas C, Rausch, Caitlin, Jabbour, Elias, Kantarjian, Hagop: Using Proton Pump Inhibitors is not Associated with Adverse Outcomes in Patients with Chronic Myeloid Leukemia Treated with Dasatinib Clinical Lymphoma, Myeloma and Leukemia. 2024.02; 24 (7): 484-487. ( PubMed , DOI )
Wang, Bofei, Reville, Patrick K, Yassouf, Mhd Yousuf, Jelloul, Fatima Z, Ly, Christopher, Desai, Poonam N, Wang, Zhe, Borges, Pamella, Veletic, Ivo, Dasdemir, Enes, others: Comprehensive characterization of IFN$γ$ signaling in acute myeloid leukemia reveals prognostic and therapeutic strategies Nature Communications. 2024.02; 15 (1): 1821. ( PubMed , DOI )
Koji Sasaki: Outcomes of Adult Patients with Philadelphia Negative B-Cell Acute Lymphoblastic Leukemia (B-ALL) Having Myeloid Type Mutations Treated with Inotuzumab/Blinatumomab Containing Frontline Regimens BLOOD. 2024; ( DOI )
Koji Sasaki: Improved survival and unique mutational signatures in small cell lung cancer arising in patients with limited tobacco use CANCER RESEARCH. 2024; 84 (6\_Supplement): 5061. ( DOI )
Haddad, F.G., Sasaki, K., Senapati, J., Xiao, L., Park, G., Abuasab, T., Venugopal, S., Rivera, D., Bazinet, A., Babakhanlou, R., Kim, K., Ong, F., Desikan, S., Pemmaraju, N., Loghavi, S., Borthakur, G., Dinardo, C., Abbas, H.A., Short, N.J., Daver, N., Jabbour, E., Garcia-Manero, G., Ravandi, F., Kantarjian, H., Kadia, T.: Outcomes of Patients with Newly Diagnosed AML and Hyperleukocytosis JCO Oncology Practice. 2024; 20 (12): 1637-1644. ( PubMed , DOI )
Koji Sasaki: Influence of co-mutational patterns in disease phenotype and clinical outcomes of chronic myelomonocytic leukemia LEUKEMIA. 2024; ( DOI )
Koji Sasaki: Phase 1b/2 Study of Magrolimab (Magro), Azacitidine (AZA) and Venetoclax (VEN) in Patients (pts) with Newly Diagnosed (ND) Older/Unfit or High Risk Acute Myeloid Leukemia (AML) and Relapsed Refractory (R/R) AML: Final Clinical Data and Genomic Markers of Resistance/Relapse BLOOD. 2024; ( DOI )
Koji Sasaki: Phase 1b/2 Study of Decitabine and Venetoclax in Combination with the Targeted Mutant IDH1 Inhibitor Olutasidenib for Patients with Relapsed/Refractory AML, High Risk MDS, or Newly Diagnosed AML Not Eligible for Chemotherapy with an IDH1 Mutation BLOOD. 2024; ( DOI )
Koji Sasaki: Phase I/II Study of the All-Oral Combination of Revumenib (SNDX-5613) with Decitabine/Cedazuridine (ASTX727) and Venetoclax (SAVE) in R/R AML BLOOD. 2024; ( DOI )
Koji Sasaki: Phase I/II Combination Study of Azacitidine and Venetoclax Post Hypomethylating Agents Failure in High Risk MDS and CMML BLOOD. 2024; ( DOI )
Jayastu Senapati, Hagop M. Kantarjian, Alexandre Bazinet, Patrick Reville, Nicholas J. Short, Naval Daver, Gautam Borthakur, Alex Bataller, Elias Jabbour, Courtney DiNardo, Fadi Haddad, Koji Sasaki, Uday Popat, Betul Oran, Amin M. Alousi, Sanam Loghavi, Elizabeth Shpall, Guillermo Garcia-Manero, Farhad Ravandi, Tapan M. Kadia: Lower intensity therapy with cladribine/low dose cytarabine/venetoclax in older patients with acute myeloid leukemia compares favorably with intensive chemotherapy among patients undergoing allogeneic stem cell transplantation Cancer. 2024; 130 (19): 3333-3343. ( PubMed , DOI )
Koji Sasaki: Low Intensity Mini-Hypercvd (mHCVD), Inotuzumab Ozogamicin (Ino) with/without Blinatumomab (Blina) in Older Patients with Newly Diagnosed Philadelphia Negative B-Cell Acute Lymphoblastic Leukemia (B-ALL): 10 Years Update BLOOD. 2024; ( DOI )
Koji Sasaki: A Phase Ib/II Study of Ivosidenib with Venetoclax f Azacitidine in IDH1-Mutated Hematologic Malignancies: A 2024 Update BLOOD. 2024; ( DOI )
Koji Sasaki: Mutation patterns and prognostic implications in acute myeloid leukemia with chromosomal 7 deletions Journal of Clinical Oncology. 2024;
Koji Sasaki: A Phase II Trial of Azacitidine with Ipilimumab, Nivolumab, or Ipilimumab and Nivolumab with or without Azacitidine in Relapsed or Refractory Myelodysplastic Syndrome BLOOD. 2024; ( DOI )
Koji Sasaki: A Phase II Trial of Azacitidine with Ipilimumab, Nivolumab, or Ipilimumab and Nivolumab in Previously Untreated Myelodysplastic Syndrome BLOOD. 2024; ( PubMed , DOI )
Koji Sasaki: Neighborhood Disadvantage Impacts Outcomes in Patients with Myelodysplastic Syndromes across Different Racial Backgrounds BLOOD. 2024; ( DOI )
Koji Sasaki: A Phase II Study of the Menin Inhibitor Revumenib in Leukemia Associated with Upregulation of HOX Genes: Trial in Progress BLOOD. 2024; ( DOI )
Koji Sasaki: Myelodysplastic Syndromes with Concomitant SF381 Mutation and Deletion of the Long Arm of Chromosome 5 (SF381del5q): Outcomes and Response to Treatment BLOOD. 2024; ( DOI )
Koji Sasaki: Myelodysplastic syndromes with concomitant SF3B1 mutation and deletion of the long arm of chromosome 5 CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2024;
Marvin-Peek, J., Sasaki, K., Kontoyiannis, D.P., Adachi, J., Ohanian, M., Takahashi, K., Issa, G.C., Kornblau, S., Abbas, H.A.: Nontuberculosis mycobacteria (NTM) infections in patients with leukemia: a single center case series Frontiers in Medicine. 2024; 11 ( DOI )
Koji Sasaki: A Retrospective Analysis of Ponatinib-Based Therapy in Patients with Myeloid Blast Phase Chronic Myeloid Leukemia: Responses Rates, Outcomes and Patterns of Relapse BLOOD. 2024; ( DOI )
Koji Sasaki: Addition of Inotuzumab Ozogamicin to Melphalan Plus Fludarabine Reduced-Intensity Conditioning Regimen of Allogeneic Transplantation in Patients with Acute Lymphoblastic Leukemia and Aggressive Lymphoid Malignancies: A Phase II Prospective Trial BLOOD. 2024; ( DOI )
Koji Sasaki: Approximation of Glomerular Filtration Rate after 1 Year Using Annual Medical Examination Data JOURNAL OF CLINICAL MEDICINE. 2024; ( DOI )
Koji Sasaki: Application of Next-Generation Cytogenetics in a Clinical Laboratory for Diagnostic Work-up of Myelodysplastic Syndromes/Neoplasms (MDS) BLOOD. 2024; ( DOI )
Koji Sasaki: Asciminib Provides Long-Term, Durable Molecular Responses in Patients with T3151-Mutated CML-CP: Final Analysis from a Phase 1 Trial BLOOD. 2024; ( DOI )
Koji Sasaki: ASXLI Mutations in AML Are Associated with a Distinct Epigenetic State Which Highlights Vulnerabilities to Specific Epigenetic-Targeted Agents BLOOD. 2024; ( DOI )
Koji Sasaki: Performance of the Molecular International Prognostic Scoring System (IPSS-M) in Myelodysplastic Syndromes Treated with Hypomethylating Agent-Based Therapy: A Multicenter Analysis BLOOD. 2024; ( DOI )
Koji Sasaki: Personalized Oral Maintenance Therapy with Decitabine/Cedazuridine (ASTX727) Combined with a Molecularly Targeted Agent (Venetoclax, Gilteritinib, Ivosidenib, or Enasidenib) in Acute Myeloid Leukemia in First Remission BLOOD. 2024; ( DOI )
Koji Sasaki: Combination Therapy with Nelarabine, Peg-Asparaginase and Venetoclax for Adults Patients with Relapsed/Refractory T-Cell ALL BLOOD. 2024; ( DOI )
Koji Sasaki: Combination of CPX-351 and Gemtuzumab Ozogamicin (GO) in Relapsed Refractory (R/R) Acute Myeloid Leukemia and Post Hypomethylating Agent (HMA) Failure High-Risk Myelodysplastic Syndrome (HR-MDS) BLOOD. 2024; ( DOI )
Koji Sasaki: CNS Involvement in Adult Patients with B-Cell Acute Lymphoblastic Leukemia BLOOD. 2024; ( DOI )
Koji Sasaki: Distinct Impact of Platinum Chemotherapies on the Fitness and Genome of Hematopoietic Stem Cells and the Risk of Therapy-Related Myeloid Neoplasms BLOOD. 2024; ( DOI )
Koji Sasaki: Identifying novel therapies from unbiased screens in AML with MECOM re-arrangement CANCER RESEARCH. 2024; 84 (6\_Supplement): 3351. ( DOI )
Koji Sasaki: Identifying 'Druggable' Targets and Preclinically Overcoming Non-Genetic/Adaptive Resistance to Menin Inhibitors in AML with MLL1r or mtNPM1 BLOOD. 2024; ( DOI )
Koji Sasaki: Impact of complete cytogenetic response on survival in patients with myelodysplastic syndromes Journal of Clinical Oncology. 2024;
Koji Sasaki: Impact of JAK2 allele burden on MF outcome in the era of ruxolitinib Journal of Clinical Oncology. 2024;
Koji Sasaki: Outcomes of Adult Patients with Newly Diagnosed IDH-Mutated Acute Myeloid Leukemia Receiving Intensive Chemotherapy Plus Venetoclax BLOOD. 2024; ( DOI )
Koji Sasaki: Impact of Flow Cytometry-Based Measurable Residual Disease Clearance Kinetics in Patients with Acute Myeloid Leukemia Undergoing Intensive Chemotherapy BLOOD. 2024; ( DOI )
Koji Sasaki: Blood-Based Proteomic Profiling Identifies Osmr As a Novel Biomarker BLOOD. 2024; 145 (25): ( PubMed , DOI )
Koji Sasaki: Blinatumomab and Ponatinib for Adults with Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Updated Results and Predictors of Relapse BLOOD. 2024; ( DOI )
Chien, Kelly S, Ong, Faustine, Kim, Kunhwa, Li, Ziyi, Kanagal-Shamanna, Rashmi, DiNardo, Courtney D, Takahashi, Koichi, Montalban-Bravo, Guillermo, Hammond, Danielle, Sasaki, Koji, others: Cancer patients with clonal hematopoiesis die from primary malignancy or comorbidities despite higher rates of transformation to myeloid neoplasms Cancer medicine. 2024; 13 (5): ( PubMed , DOI )
Koji Sasaki: Updated Results of the Combination of Mini-Hyper-CVD with Inotuzumab Ozogamicin and Blinatumomab in Patients with Relapsed/Refractory B-Cell ALL BLOOD. 2024; ( DOI )
Koji Sasaki: Predictors for Time-to-First-Treatment in Patients with Del(17p) and/or TP53-Mutated Chronic Lymphocytic Leukemia BLOOD. 2024; ( DOI )
Koji Sasaki: Characteristics of Myelodysplastic Syndromes with Idiopathic Pulmonary Fibrosis BLOOD. 2024; ( DOI )
Koji Sasaki: Choosing the Best Firstline Drug: Does Efficacy Make You Think About Cost? CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2024;
Koji Sasaki: Chemotherapy Free Regimen of Inotuzumab Ozogamicin and Blinatumomab in Frontline Therapy of Older Patients with Philadelphia Negative B-Cell Acute Lymphoblastic Leukemia BLOOD. 2024; ( DOI )
Koji Sasaki: Early Obinutuzumab Significantly Increases Bone Marrow Undetectable MRD (10-4 sensitivity) (uMRD4) Rate When Combined with Acalabrutinib and Venetoclax in a Randomized Phase II Trial for Treatment Naive CLL BLOOD. 2024; ( DOI )
Koji Sasaki: Efficacy and Safety of Asciminib in Chronic Myeloid Leukemia in Chronic Phase (CML-CP): Interim Results from the Phase 2 ASC2ESCALATE Trial in the Cohort of Patients (Pts) after 1 Prior Tyrosine Kinase Inhibitor (TKI) BLOOD. 2024; ( DOI )
Koji Sasaki: Early Predictors of Treatment-Free Remission in Chronic Myeloid Leukemia BLOOD. 2024; ( DOI )
Koji Sasaki: Efficacy of Combinations of Targeted Agents Against Dependencies in Mecom Rearranged AML Identified By Unbiased Chemical and CRISPR Screens BLOOD. 2024; ( DOI )
Koji Sasaki: Evaluating the Safety of Tyrosine Kinase Inhibitor Discontinuation in Adult Patients with Ph plus ALL Not Undergoing Allogeneic Transplant BLOOD. 2024; ( DOI )
Sasaki, Koji, Kantarjian, Hagop, Montalban-Bravo, Guillermo, Hammond, Danielle, Jabbour, Elias, Kanagal-Shamanna, Rashmi, Chien, Kelly, Garcia-Manero, Guillermo: Eosinophilia During Lenalidomide Therapy in Myelodysplastic Syndrome Clinical Lymphoma Myeloma and Leukemia. 2024; 24 (9): 629-633. ( PubMed , DOI )
Koji Sasaki: FLAG IDA Venetoclax in Newly Diagnosed Pediatric and AYA Patients with AML BLOOD. 2024; ( DOI )
Nasnas, Patrice E, Jabbour, Elias J, Sasaki, Koji, Issa, Ghayas C, Masarova, Lucia, Short, Nicholas J, Haddad, Fadi G: Failure of treatment-free remission after a prolonged deep molecular response in patients with chronic myeloid leukemia Acta Haematologica. 2024; 148 (1): 105-110. ( PubMed , DOI )
Koji Sasaki: Genomic Profiling of T-Cell Acute Lymphoblastic Leukemia/Lymphoma (T-ALL) for Identification of Driver Aberrations Using Combined Next Generation Sequencing and Optical Genome Mapping in Clinical Diagnostic Laboratory BLOOD. 2024; ( DOI )
Koji Sasaki: Genomic evolution of patients with myeloid neoplasms and known antecedent clonal hematopoiesis Journal of Clinical Oncology. 2024;
Koji Sasaki: Genomic Evolution of Patients With Myeloid Neoplasms and Known Antecedent Clonal Hematopoiesis CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2024;
Koji Sasaki: Clinical Characteristics and Outcomes of NUP98 Rearrangement in Adults with Acute Leukemia CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2024;
Koji Sasaki: Outcomes of patients with bone marrow fibrosis in de novo and secondary acute myeloid leukemia Journal of Clinical Oncology. 2024;
Koji Sasaki: Risk Stratification in Hypomethylating Agent-Treated Patients With Myelodysplastic Syndromes: A Multivariate Model CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2024;
Fadi G. Haddad, Koji Sasaki, Lewis Nasr, Nicholas J. Short, Tapan Kadia, Sara Dellasala, Jorge Cortes, Franck E. Nicolini, Ghayas C. Issa, Elias Jabbour, Hagop Kantarjian: Results of ponatinib as frontline therapy for chronic myeloid leukemia in chronic phase Cancer. 2024; 130 (19): 3344-3352. ( PubMed , DOI )
Koji Sasaki: Clinical Outcomes Associated with NPM1 Mutations in Newly Diagnosed AML BLOOD. 2024; ( DOI )
Koji Sasaki: Oral Decitabine/Cedazuridine in Patients with MDS and TP53 Mutations: A Propensity Score Matching Analysis from the Phase II and III Trials BLOOD. 2024; ( DOI )
Koji Sasaki: Clinical Outcomes of Patients with AML Receiving Lower Intensity Chemotherapy with or without the Use of Granulocyte-Colony Stimulating Factor (GCSF) BLOOD. 2024; ( DOI )
Koji Sasaki: Clinical Outcomes Using Frontline "Triplet" Regimens for Newly Diagnosed IDH-Mutated Acute Myeloid Leukemia (AML): A Pooled Analysis of Two Phase Ib/2 Clinical Trials BLOOD. 2024; ( DOI )
Koji Sasaki: Comprehensive Characteristics and Outcomes of Myeloid Neoplasms Following Chimeric Antigen Receptor T-Cell Therapy for Other Hematologic Malignancies BLOOD. 2024; ( DOI )
Koji Sasaki: Time-Limited Therapy with Zanubrutinib Plus Rituximab in Patients with Treatment-Naive Chronic Lymphocytic Leukemia: Early Results of an Ongoing Phase II Trial BLOOD. 2024; ( DOI )
Koji Sasaki: Phase II Study of Inotuzumab Ozogamicin for the Treatment of Measurable Residual Disease-Positive B-Cell Acute Lymphoblastic Leukemia: 3-Year Update BLOOD. 2024; ( DOI )
Koji Sasaki: Treatment Intensity in Acute Myeloid Leukemia with Extramedullary Disease BLOOD. 2024; ( DOI )
Haddad, FG, Sasaki, K, Issa, GC, others: Outcome of patients with chronic myeloid leukemia after more than 10 years of follow-up Hemoglobin. 2023.12; 1 (343): 070. ( DOI )
Koji Sasaki: Deeper Insight into Splicing Mutations in Myelofibrosis BLOOD. 2023.11; 142 (Supplement 1): 4580. ( DOI )
Koji Sasaki: Characterization of MDS and CMML Patients Harboring Trisomy 8 Abnormality: Clinical, Autoimmune, and Mutational Features BLOOD. 2023.11; 142 (Supplement 1): 1881. ( DOI )
Koji Sasaki: Protective Role of Oxaliplatin Among Platinum-Based Therapies in the Development of Therapy-Related Myeloid Neoplasms BLOOD. 2023.11; 142 (Supplement 1): 4220. ( DOI )
Koji Sasaki: Cladribine-Based Chemotherapy for Patients with Secondary Acute Myeloid Leukemia (AML) Arising after Myeloproliferative Neoplasms (MPNs) BLOOD. 2023.11; 142 (Supplement 1): 4264. ( DOI )
Koji Sasaki: Clinical Characteristics and Outcomes of Therapy-Related Chronic Myelomonocytic Leukemia: Analysis of a Large Cohort BLOOD. 2023.11; 142 (Supplement 1): 3237. ( DOI )
Bataller, Alex, Loghavi, Sanam, Gerstein, Yoheved, Bazinet, Alexandre, Sasaki, Koji, Chien, Kelly S, Hammond, Danielle, Montalban-Bravo, Guillermo, Borthakur, Gautam, Short, Nicholas, others: MDS-208 Characteristics and Outcomes of Patients With Myelodysplastic Syndrome and DDX41 Mutation Clinical Lymphoma Myeloma and Leukemia. 2023.09; 23 S357-S358. ( DOI )
Koji Sasaki: ASC2ESCALATE: A US, Phase II Open-Label, Single-Arm, Dose-Escalation Study of Asciminib Monotherapy in Second-Line (2L) and First-Line (1L) Treatment of Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP) CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2023.09; 23 S348-S349. ( DOI )
Koji Sasaki: Causes of Death in Patients With Myelodysplastic Syndrome and Spliceosome Mutations CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2023.09; 23 S374-S375. ( DOI )
Koji Sasaki: Characteristics and Outcomes of Patients With Myelodysplastic Syndrome and DDX41 Mutation CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2023.09; 23 ( DOI )
Koji Sasaki: First-in-Human Phase I Study of ELVN-001, an Oral, Selective BCR::ABL1 Tyrosine Kinase Inhibitor, in Patients With Chronic Myeloid Leukemia Who Failed Prior Tyrosine Kinase Inhibitors CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2023.09; 23 ( DOI )
Koji Sasaki: T-Cell Exhaustion and Immune Checkpoint VISTA Overexpression Are Associated With Suboptimal Response to Tyrosine Kinase Inhibitors (TKIs) in Patients With Chronic Myeloid Leukemia (CML) CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2023.09; 23 ( DOI )
Koji Sasaki: Outcomes of individuals with clonal hematopoiesis evaluated at a cancer center. JOURNAL OF CLINICAL ONCOLOGY. 2023.08; 7 (S3): ( DOI )
Bidikian, Aram, Short, Nicholas, Ganesh, Ramya, Pike, Allison, Sasaki, Koji, Jabbour, Elias, Andreeff, Michael, Cortes, Jorge, Issa, Ghayas: P687: EARLY RESULTS OF A PHASE II STUDY EVALUATING THE ADDITION OF ASCIMINIB TO ERADICATE MINIMAL RESIDUAL DISEASE IN CHRONIC MYELOID LEUKEMIA HemaSphere. 2023.08; 7 (S3): ( DOI )
Bidikian, Aram, Haddad, Fadi, Sasaki, Koji, Issa, Ghayas, Kadia, Tapan, Jain, Nitin, Alvarado, Yesid, Short, Nicholas, Yilmaz, Musa, Masarova, Lucia, others: P672: CHARACTERISTICS AND OUTCOMES OF PATIENTS WITH CHRONIC MYELOID LEUKEMIA AND T315I MUTATION AFTER FAILURE OF PRIOR THERAPIES HemaSphere. 2023.08; 7 (S3): ( DOI )
Nguyen, Daniel, Kantarjian, Hagop, Bidikian, Aram, Dinardo, Courtney, Kadia, Tapan, Daver, Naval, Borthakur, Gautam, Jabbour, Elias, Yilmaz, Musa, Short, Nicholas, others: P535: OUTCOMES OF INVESTIGATIONAL AGENTS VS STANDARD THERAPIES IN AML AT SALVAGE 2 AND BEYOND HemaSphere. 2023.08; 7 (S3): ( DOI )
Short, Nicholas, Macaron, Walid, Dinardo, Courtney, Daver, Naval, Yilmaz, Musa, Borthakur, Gautam, Montalban-Bravo, Guillermo, Garcia-Manero, Guillermo, Issa, Ghayas, Sasaki, Koji, others: P485: Azacitidine, venetoclax and gilteritinib for patients with newly diagnosed flt3-mutated acute myeloid leukemia: A subgroup analysis from a phase ii study HemaSphere. 2023.08; 7 (S3):
Atallah, Ehab, Mauro, Michael, Sasaki, Koji, Levy, Moshe Yair, Koller, Paul, Sadek, Islam, Yang, Daisy, Ruckel-Kumar, Julie, Khan, Mahmudul, Cortes, Jorge: P688: ASC2ESCALATE: A US PHASE 2, OPEN-LABEL, SINGLE-ARM, DOSE-ESCALATION STUDY OF ASCIMINIB MONOTHERAPY IN 2ND-LINE (2L) TREATMENT OF PATIENTS (PTS) WITH CHRONIC MYELOID LEUKEMIA IN CHRONIC PHASE (CML-CP) HemaSphere. 2023.08; 7 (S3):
Urrutia, Samuel, Chien, Kelly, Ziyi, LI, Bataller, Alex, Almanza, Emmanuel, Sasaki, Koji, Montalban-Bravo, Guillermo, Short, Nicholas, Jabbour, Elias, Kadia, Tapan, others: P748: IPSS-M PERFORMANCE IN PATIENTS WITH MYELODYSPLASTIC SYNDROME AT THE TIME OF HYPOMETHYLATING AGENT FAILURE HemaSphere. 2023.08; 7 (S3): ( DOI )
Urrutia, Samuel, Almanza, Emmanuel, Bataller, Alex, Sasaki, Koji, Chien, Kelly, Kanagal-Shamanna, Rashmi, Montalban-Bravo, Guillermo, Bueso-Ramos, Carlos, Pierce, Sherry, Kantarjian, Hagop, others: P743: CLINICAL OUTCOMES OF PATIENTS WITH MYELODYSPLASTIC SYNDROME AND SPLICEOSOME MUTATIONS HemaSphere. 2023.08; 7 (S3): ( DOI )
Bazinet, Alexandre, Arani, Naszrin, Chien, Kelly, Hammond, Danielle, Kadia, Tapan, Borthakur, Gautam, Alvarado, Yesid, Sasaki, Koji, Dinardo, Courtney, Pemmaraju, Naveen, others: P736: ANALYSIS OF RESPONSE RATES AND OUTCOMES IN ERYTHROID-PREDOMINANT MYELODYSPLASTIC SYNDROMES (MDS) TREATED WITH VENETOCLAX-BASED REGIMENS HemaSphere. 2023.08; 7 (S3): ( DOI )
Chien, Kelly, Urrutia, Samuel, Ziyi, LI, Kanagal-Shamanna, Rashmi, Almanza, Emmanuel, Abuasab, Tareq, Gener, Georgina, Bataller, Alex, Bazinet, Alexandre, Montalban-Bravo, Guillermo, others: P730: EVOLUTION OF IPSS-M RISK CATEGORIES IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES FROM DIAGNOSIS TO HYPOMETHYLATING AGENT FAILURE HemaSphere. 2023.08; 7 (S3):
Urrutia, Samuel, Ziyi, LI, Almanza, Emmanuel, Bataller, Alex, Kanagal-Shamanna, Rashmi, Senapati, Jayastu, Sasaki, Koji, Chien, Kelly, Montalban-Bravo, Guillermo, Dinardo, Courtney, others: P728: EVALUATION OF IPSS-M IN PATIENTS WITH MYELODYSPLASTIC SYNDROME AND SPLICEOSOME MUTATIONS HemaSphere. 2023.08; 7 (S3): ( DOI )
Bazinet, Alexandre, Desikan, Sai Prasad, Ziyi, LI, Venugopal, Sangeetha, Urrutia, Samuel, Montalban-Bravo, Guillermo, Sasaki, Koji, Chien, Kelly, Hammond, Danielle, Kanagal-Shamanna, Rashmi, others: P723: CLINICAL AND MOLECULAR ASSOCIATIONS WITH OUTCOMES IN HIGHER RISK MYELODYSPLASTIC SYNDROMES TREATED WITH HYPOMETHYLATING AGENTS PLUS VENETOCLAX HemaSphere. 2023.08; 7 (S3):
Haddad, Fadi, Jabbour, Elias, Nasnas, Cedric, Short, Nicholas, Macaron, Walid, Zoghbi, Marianne, Nasr, Lewis, Jain, Nitin, Almanza, Emmanuel, Sasaki, Koji, others: S119: COMBINATION OF MINI-HYPER-CVD AND INOTUZUMAB (INO) FOLLOWED BY BLINATUMOMAB (BLINA) CONSOLIDATION IN PATIENTS WITH RELAPSED/REFRACTORY (R/R) ACUTE LYMPHOBLASTIC LEUKEMIA (ALL): A PHASE II TRIAL HemaSphere. 2023.08; 7 (S3): ( DOI )
Holly Ann Hill, Preetesh Jain, Chi Young Ok, Koji Sasaki, Han Chen, Michael L. Wang, Ken Chen: Supplementary Figure 2 from Integrative Prognostic Machine-Learning Models in Mantle Cell Lymphoma Cancer Research Communications. 2023.07; ( DOI )
Holly Ann Hill, Preetesh Jain, Chi Young Ok, Koji Sasaki, Han Chen, Michael L. Wang, Ken Chen: Supplementary Table 2 from Integrative Prognostic Machine-Learning Models in Mantle Cell Lymphoma 2023.07; ( DOI )
Holly Ann Hill, Preetesh Jain, Chi Young Ok, Koji Sasaki, Han Chen, Michael L. Wang, Ken Chen: Supplementary Table 1 from Integrative Prognostic Machine-Learning Models in Mantle Cell Lymphoma 2023.07; ( DOI )
Koji Sasaki: Outcomes of individuals with clonal hematopoiesis evaluated at a cancer center. JOURNAL OF CLINICAL ONCOLOGY. 2023.06; 41 (16_suppl): ( DOI )
Almanza-Huante E, Bataller A, Urrutia S, Gener-Ricos G, Briski RE, Kanagal-Shamanna R, Lu KH, Westin SN, Yap TA, Takahashi K, Ravandi F, Alvarado Y, Garcia-Manero G: Outcomes of patients with therapy-related myeloid neoplasms after treatment with poly(ADP-ribose) polymerase proteins inhibitors for solid tumours. British journal of haematology. 2023.03; 201 (3): e25-e29. ( PubMed , DOI )
Koji Sasaki: Outcomes of Patients (pts) with Newly Diagnosed Acute Myeloid Leukemia (AML) and TP53 mutation/Loss Treated on the Phase 2 Study of Venetoclax (Ven) Added to Alternating Cladribine (Clad) Plus Low-Dose Cytarabine (LDAC) and Azacitidine (Aza): A Subgroup Analysis BLOOD. 2023; 142 4282. ( DOI )
Koji Sasaki: Outcomes of myeloid malignancies in patients previously treated with PARP inhibitors for solid malignancies: A single institution experience. JOURNAL OF CLINICAL ONCOLOGY. 2023; ( DOI )
Montalban-Bravo, Guillermo, Swanson, David, Kanagal-Shamanna, Rashmi, Rodriguez-Sevilla, Juan Jose, Hammond, Danielle E, Chien, Kelly S, Sasaki, Koji, Jabbour, Elias, DiNardo, Courtney D, Takahashi, Koichi, others: Influence of co-mutational patterns in disease phenotype and clinical outcomes of chronic myelomonocytic leukemia Blood. 2023; 142 (5): 4601. ( PubMed , DOI )
Koji Sasaki: Inotuzumab ozogamicin (INO) for the treatment of measurable residual disease (MRD) in patients with B-cell acute lymphoblastic leukemia (B-ALL): Results from a phase II study. JOURNAL OF CLINICAL ONCOLOGY. 2023; ( DOI )
Koji Sasaki: Inotuzumab ozogamicin (INO) for the treatment of measurable residual disease (MRD) in patients with B-cell acute lymphoblastic leukemia (B-ALL): Results from a phase II study JOURNAL OF CLINICAL ONCOLOGY. 2023;
Koji Sasaki: Phase 2 Study of Dasatinib with and without Venetoclax in Patients with Early Chronic Phase Chronic Myeloid Leukemia (ECP-CML) BLOOD. 2023; 142 870. ( DOI )
Koji Sasaki: Severe RAS-Associated Lymphoproliferative Disease Case with Increasing αβ Double-Negative T Cells with Atypical Features Journal of Clinical Immunology. 2023; ( DOI )
Koji Sasaki: A phase 2 study of the combination of decitabine (DAC), venetoclax (VEN), and ponatinib in patients (Pts) with chronic myeloid leukemia (CML) in accelerated phase (AP)/myeloid blast phase (MBP) or Philadelphia-chromosome positive (Ph plus ) acute myeloid leukemia (AML). JOURNAL OF CLINICAL ONCOLOGY. 2023; ( DOI )
Koji Sasaki: A phase 2 study of the combination of decitabine (DAC), venetoclax (VEN), and ponatinib in patients (Pts) with chronic myeloid leukemia (CML) in accelerated phase (AP)/myeloid blast phase (MBP) or Philadelphia-chromosome positive (Ph plus ) acute myeloid leukemia (AML) JOURNAL OF CLINICAL ONCOLOGY. 2023;
Koji Sasaki: Actionable Findings from an Unbiased Drug Screen for Novel Single Agent and Combination Therapies Against AML with Mecom Re-Arrangement BLOOD. 2023; 142 1419. ( DOI )
Nishida, Yuki, Scruggs, Darah A, Ayoub, Edward, Ostermann, Lauren B, Patsilevas, Tallie, Ruvolo, Vivian R, Mak, Po Yee, Carter, Bing Z, Boettcher, Steffen, Maiti, Abhishek, others: Abstract A31: C-MYC Targeting by Degradation: Novel Dual c-MYC/GSPT1 Degrader GT19715 Induces TP53-independent Cell Death in MYC-amplified Acute Myeloid Leukemia and Lymphomas Blood Cancer Discovery. 2023; 4 (3\_Supplement): A31.
Koji Sasaki: NPM1-Mutated Myeloid Neoplasms: Updated Outcomes with High-Intensive Chemotherapy Regardless of the Blast Percentage BLOOD. 2023; 142 957. ( DOI )
Koji Sasaki: Addition of Inotuzumab Ozogamicin to the Conditioning Regimen of Allogeneic Stem Cell Transplantation (allo-SCT) for Relapsed CD22 (+) Lymphoid Malignancies: Long-Term Survival Results BLOOD. 2023; 142 233. ( DOI )
Koji Sasaki: ASC2ESCALATE: A US Phase 2, Open-Label, Single-Arm, Dose-Escalation Study of Asciminib (ASC) Monotherapy in Patients (Pts) with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) As Second-Line (2L) and First-Line (1L) Treatment BLOOD. 2023; 142 6389. ( DOI )
Koji Sasaki: Asciminib (ASC) in Combination with Imatinib (IMA), Nilotinib (NIL), or Dasatinib (DAS) May be a Potential Treatment (Tx) Option in Patients (Pts) with Philadelphia ChromosomePositive Chronic Myeloid Leukemia in Chronic Phase or Accelerated Phase (Ph plus CMLCP/AP): Final Results from the Asciminib Phase 1 Study BLOOD. 2023; 142 868. ( DOI )
Koji Sasaki: ASC2ESCALATE: A US phase 2, single-arm, dose-escalation study of asciminib monotherapy in patients (pts) with chronic myeloid leukemia in chronic phase (CML-CP) previously treated with 1 prior tyrosine kinase inhibitor (TKI). JOURNAL OF CLINICAL ONCOLOGY. 2023; ( DOI )
Koji Sasaki: ASC2ESCALATE: A US phase 2, single-arm, dose-escalation study of asciminib monotherapy in patients (pts) with chronic myeloid leukemia in chronic phase (CML-CP) previously treated with 1 prior tyrosine kinase inhibitor (TKI) JOURNAL OF CLINICAL ONCOLOGY. 2023;
Koji Sasaki: Performance of the Molecular International Prognostic Scoring System (IPSS-M) in Hypomethylating Agent-Treated Patients with Myelodysplastic Syndromes BLOOD. 2023; 142 1857. ( DOI )
Koji Sasaki: IFN. Signaling in Acute Myeloid Leukemia Mediates Immunomodulation and Reveals Therapeutic Strategies BLOOD. 2023; 142 2796. ( DOI )
Koji Sasaki: Ibrutinib, Fludarabine, Cyclophosphamide and Obinutuzumab ( iFCG) for Firstline Treatment of Patients with CLL with Mutated IGHV and without Del(17p)/ TP53 Mutation: Six-Year Follow-up Analyses BLOOD. 2023; 142 3267. ( DOI )
Koji Sasaki: Azacitidine Plus Venetoclax Maintenance in Acute Myeloid Leukemia Produces Sustained Remissions with Low Toxicity: Results of a Phase 2 Study BLOOD. 2023; 142 2884. ( DOI )
Koji Sasaki: Phase II trial of mini-hyper-CVD-inotuzumab (InO) followed by blinatumomab (blina) consolidation in patients with relapsed/refractory (R/R) acute lymphoblastic leukemia (ALL). JOURNAL OF CLINICAL ONCOLOGY. 2023; ( DOI )
Koji Sasaki: With up to 8 Years of Therapy, Asciminib (ASC) Monotherapy Demonstrated Continued Favorable Efficacy, Safety, and Tolerability in Patients (Pts) with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase (Ph plus CML-CP) without the T315I Mutation: Final Results from the Phase 1 X2101 Study BLOOD. 2023; ( DOI )
Koji Sasaki: Characteristics and Outcomes of Patients With Acute Myeloid Leukemia and DDX41 Mutation CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2023; 23
Hochhaus, Andreas, Kim, Dong-Wook, Cortes, Jorge, Sasaki, Koji, Mauro, Michael, Hughes, Timothy P, Breccia, Massimo, Talpaz, Moshe, Minami, Hironobu, Goh, Yeow Tee, others: With up to 8 Years of Therapy, Asciminib (ASC) Monotherapy Demonstrated Continued Favorable Efficacy, Safety, and Tolerability in Patients (Pts) with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase (Ph+ CML-CP) without the T315I Mutation: Final Results from the Phase 1 X2101 Study Blood. 2023; 142 450.
Koji Sasaki: Dorsal Column Myelopathy Following Intrathecal Chemotherapy for Leukemia INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 2023; 117 (2): e486-e487.
Koji Sasaki: Outcomes of myeloid malignancies in patients previously treated with PARP inhibitors for solid malignancies: A single institution experience JOURNAL OF CLINICAL ONCOLOGY. 2023;
Montalban-Bravo, Guillermo, Kanagal-Shamanna, Rashmi, Ziyi, LI, Hammond, Danielle, Chien, Kelly, Rodriguez-Sevilla, Juan Jose, Sasaki, Koji, Jabbour, Elias, Dinardo, Courtney, Takahashi, Koichi, others: P496: PHENOTYPIC SUBTYPES OF LEUKEMIC TRANSFORMATION IN CHRONIC MYELOMONOCYTIC LEUKEMIA HemaSphere. 2023; 7 (S3):
Koji Sasaki: Phase II trial of mini-hyper-CVD-inotuzumab (InO) followed by blinatumomab (blina) consolidation in patients with relapsed/refractory (R/R) acute lymphoblastic leukemia (ALL) JOURNAL OF CLINICAL ONCOLOGY. 2023;
Hochhaus, Andreas, Réa, Delphine, Boquimpani, Carla, Minami, Yosuke, Cortes, Jorge E, Hughes, Timothy P, Apperley, Jane F, Lomaia, Elza, Voloshin, Sergey, Turkina, Anna, others: Porównanie asciminibu z bosutynibem w leczeniu pacjentów z przewlekłą białaczką szpikową w fazie przewlekłej leczonych wczésniej co najmniej dwoma inhibitorami kinazy tyrozynowej: dłuższa obserwacja ASCEMBL Hematologia-Edukacja. 2023; 3 (3-4): 119-133.
Koji Sasaki: Role and Prevalence of Risk Factors That Trigger Therapy Related Myeloid Neoplasms (TRMN) in Patients with Previous Treated Breast Cancer BLOOD. 2023; 142 4593. ( DOI )
Koji Sasaki: Cladribine, High-Dose AraC, Plus Gemtuzumab Ozogamicin (CLAG-GO) As Frontline Intensive Therapy for Fit Patients with Core-Binding Factor Acute Myeloid Leukemia: Preliminary Results BLOOD. 2023; 142 2903. ( DOI )
Koji Sasaki: Clinical and Molecular Characterization of Patients with Therapy Related Myeloid Neoplasms ( TRMN) BLOOD. 2023; 142 3224. ( DOI )
Koji Sasaki: Sustained Efficacy and Safety with Asciminib (ASC) after Almost 4 Years of Median Followup from Ascembl, a Phase 3 Study of ASC Vs Bosutinib (BOS) in Patients (Pts) with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) after ≥2 Prior Tyrosine Kinase Inhibitors (TKIs): An End of Study Treatment (EOS Tx) Update, Including Results from Switch Population BLOOD. 2023; ( DOI )
Mauro, Michael, Minami, Yosuke, Hochhaus, Andreas, Lomaia, Elza, Voloshin, Sergei, Turkina, Anna, Kim, Dong-Wook, Apperley, Jane F, Cortes, Jorge, Abdo, Andre NR, others: Sustained Efficacy and Safety with Asciminib (ASC) after Almost 4 Years of Median Follow-up from Ascembl, a Phase 3 Study of ASC Vs Bosutinib (BOS) in Patients (Pts) with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) after≥ 2 Prior Tyrosine Kinase Inhibitors (TKIs): An End of Study Treatment (EOS Tx) Update, Including Results from Switch Population Blood. 2023; 142 4536.
Koji Sasaki: Oral Decitabine/Cedazuridine with Venetoclax in High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia: Analysis By Different Response Criteria BLOOD. 2023; 142 3228. ( DOI )
Koji Sasaki: Clinical and transcriptomic analysis demonstrates improved survival and unique gene expression signatures among SCLC arising in patients with minimal tobacco use CANCER RESEARCH. 2023; 83 (7\_Supplement): 1398. ( DOI )
Koji Sasaki: Combined Ibrutinib and Venetoclax for First-Line Treatment of Patients with Chronic Lymphocytic Leukemia (CLL): 5-Year Follow-up Data BLOOD. 2023; 142 4635. ( DOI )
Koji Sasaki: Clinicopathologic Predictors of Hypomethylating Agent Failure in Patients with Myelodysplastic Syndromes BLOOD. 2023; 142 4616. ( DOI )
Koji Sasaki: Comprehensive Characterization of Evolution of Genomic Complexity By Structural Variant and Mutational Profiling in Myelodysplastic Syndrome Patients with Hypomethylating Agent Failure BLOOD. 2023; 142 4612. ( DOI )
Koji Sasaki: Phase Ib/2 Study of Oral Decitabine/Cedazuridine (ASTX727) and Venetoclax in Combination with the Targeted Mutant IDH1 Inhibitor Ivosidenib or the Targeted Mutant IDH2 Inhibitor Enasidenib: 2023 Update BLOOD. 2023; 142 968. ( DOI )
Issa G, Bidikian A, Venugopal S, Konopleva M, DiNardo C, Kadia T, Borthakur G, Jabbour E, Pemmaraju N, Yilmaz M, Short N, Maiti A, Sasaki K, Daver N: Clinical outcomes associated with NPM1 mutations in patients with relapsed or refractory AML Blood advances. 2022.11;
Kim, Kunhwa, Ahaneku, Hycienth, Deborah, M, Sasaki, Koji, Hammond, Danielle, Chien, Kelly, Adachi, Javier, Ferrajoli, Alessandra: P1590: OUTCOME OF HYPERBARIC OXYGEN THERAPY IN PATIENTS WITH HEMATOLOGIC MALIGNANCIES--A TERTIARY CANCER CENTER EXPERIENCE HemaSphere. 2022.06; 6 1471-1472.
Kim, Kunhwa, Chien, Kelly, Faustine, Ong, Montalban-Bravo, Guilermo, Kanagal-Shamanna, Rashmi, Kadia, Tapan, Jabbour, Elias, Alvarado, Yesid, Sasaki, Koji, Dong, Xia Qing, others: P769: MUTATION PROFILES AND RISK STRATIFICATION IN HYPOCELLULAR MYELODYSPLASTIC SYNDROME HemaSphere. 2022.06; 6 664-665. ( DOI )
Yang, Hui, Garcia-Manero, Guillermo, Sasaki, Koji, Montalban-Bravo, Guillermo, Tang, Zhenya, Wei, Yue, Kadia, Tapan, Chien, Kelly, Rush, Diana, Nguyen, Ha, others: P767: CLINICAL SIGNIFICANCE OF ROUTINE HIGH-RESOLUTION STRUCURAL VARIANT PROFILING IN MYELODYSPLASTIC SYNDROMES HemaSphere. 2022.06; 6 662-663. ( DOI )
Haddad, Fadi, Kantarjian, Hagop, Jabbour, Elias, Short, Nicholas, Bidikian, Aram, Ning, Jing, Xiao, Lianchun, Pemmaraju, Naveen, Marx, Kayleigh, Ravandi, Farhad, others: P703: ASSOCIATION BETWEEN BARIATRIC SURGERY AND OUTCOMES IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA TREATED WITH ORAL TYROSINE KINASE INHIBITORS HemaSphere. 2022.06; 6 598-599. ( DOI )
Bidikian, Aram, Kantarjian, Hagop, Jabbour, Elias, Short, Nicholas, Ravandi, Farhad, Issa, Ghayas, Sasaki, Koji: P695: Prognostic impact of ASXL1 mutations in chronic phase cml HemaSphere. 2022.06; 6 590-591. ( DOI )
F. Darbaniyan, G. Montalban Bravo, K. S. Chien, R. Kanagal Shamanna, K. sasaki, H. Yang, K. A. Soltysiak, Z. Li, K.-A. Do, G. Garcia-Manero: P762: NONLINIEAR IMPACT OF CLINICAL FEATURES ON THE SURVIVAL OUTCOME OF MYELODYSPLASTIC SYNDROMES PATIENTS HemaSphere. 2022.06; 6 ( DOI )
Konopleva, Marina, Yap, Timothy, Daver, Naval, Mahendra, Mikhila, Zhang, Jixiang, Kamiya-Matsuoka, Carlos, Meric-Bernstam, Funda, Kantarjian, Hagop, Ravandi, Farhad, Collins, Meghan, others: Targeting Oxidative Phosphorylation with a Mitochondrial Complex I Inhibitor is limited by Mechanism-based Toxicity 2022.04; ( DOI )
Short, Nicholas, Kantarjian, Hagop, Konopleva, Marina, Jain, Nitin, Ravandi, Farhad, Huang, Xuelin, Macaron, Walid, Wierda, William, Borthakur, Gautam, Kadia, Tapan, others: S114: ponatinib and blinatumomab for patients with philadelphia chromosome-positive acute lymphoblastic leukemia: updated results from a phase II study HemaSphere. 2022; 6 15-16.
Jain, Nitin, Thompson, Philip, Burger, Jan, Ferrajoli, Alessandra, Takahashi, Koichi, Estrov, Zeev, Borthakur, Gautam, Bose, Prithviraj, Kadia, Tapan, Pemmaraju, Naveen, others: S149: Long term outcomes of iFCG regimen for firstline treatment of patients with CLL with mutated IGHV and without Del (17p)/TP53 mutation HemaSphere. 2022; 6 50-51.
Rea, D, Hochhaus, A, Mauro, MJ, Minami, Y, Lomaia, E, Voloshin, S, Turkina, A, Kim, D-W, Apperley, JF, Cortes, JE, others: S155: EFFICACY AND SAFETY RESULTS FROM ASCEMBL, A PHASE 3 STUDY OF ASCIMINIB VS BOSUTINIB IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA IN CHRONIC PHASE AFTER≥ 2 PRIOR TYROSINE KINASE INHIBITORS: WK 96 UPDATE HemaSphere. 2022; 6 56-57.
Koji Sasaki: 96-Week Update from the Phase 3 ASCEMBL Study for Evaluating the Safety and Efficacy of Asciminib versus Bosutinib in Patients with chronic phase chronic myeloid Leukemia after Pretreatment with 2 TKIs ONCOLOGY RESEARCH AND TREATMENT. 2022;
Koji Sasaki: Low-dose dasatinib 50 mg/day versus standard-dose dasatinib 100 mg/day as frontline therapy in chronic myeloid leukemia in chronic phase: A propensity score analysis AMERICAN JOURNAL OF HEMATOLOGY. 2022; 138 631. ( DOI )
Abuasab, T., Mohamed, S.F., Biostatistics, H.H., Biostatistics, X.W., Sasaki, K., Yilmaz, M., Kadia, T., DiNardo, C., Daver, N., Pemmaraju, N., Rav, i, F., Kantarjian, H., Garcia-Manero, G., Takahashi, K.: AML-387 Clinical Characteristics of Secondary Myeloid Neoplasms (MNs) in Patients With Inflammatory Bowel Disease (IBD) Clinical Lymphoma, Myeloma and Leukemia. 2022; 22 S243. ( PubMed , DOI )
Koji Sasaki: Effect of Early Caffeine Therapy on the Prevention of Severe Hyperkalemia in Preterm Infants PEDIATRICS. 2022; 149 (1 Meeting Abstracts February 2022): 667.
Hughes, Timothy, Cortes, Jorge E, Réa, Delphine, Mauro, Michael J, Hochhaus, Andreas, Kim, D-W, Sasaki, Koji, Lang, Fabian, Heinrich, Michael C, Breccia, M, others: P704: ASCIMINIB PROVIDES DURABLE MOLECULAR RESPONSES IN PATIENTS (PTS) WITH CHRONIC MYELOID LEUKEMIA IN CHRONIC PHASE (CML-CP) WITH THE T315I MUTATION: UPDATED EFFICACY AND SAFETY DATA FROM A PHASE I TRIAL HemaSphere. 2022; 6 599-600.
Koji Sasaki: HEALTH CARE RESOURCE UTILIZATION WITH ASCIMINIB AND BOSUTINIB AMONG ADULTS WITH CHRONIC MYELOID LEUKEMIA IN CHRONIC PHASE PREVIOUSLY TREATED WITH=2 TYROSINE KINASE INHIBITORS: WEEK 48 AND WEEK 96 RESULTS FROM ASCEMBL TRIAL VALUE IN HEALTH. 2022;
Senapati, Jayastu, Kantarjian, Hagop, Short, Nicholas, Alvarado, Yesid, Burger, Jan, Jain, Nitin, Konopleva, Marina, Ravandi, Farhad, DiNardo, Courtney, Masarova, Lucia, others: P368: A PHASE II STUDY OF INOTUZUMAB OZOGAMICIN FOR THE TREATMENT OF MEASURABLE RESIDUAL DISEASE-POSITIVE B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA HemaSphere. 2022; 6 268-269.
Short, Nicholas, Kantarjian, Hagop, Ravandi, Farhad, Yilmaz, Musa, Kadia, Tapan, Thompson, Philip, Huang, Xuelin, Konopleva, Marina, Ferrajoli, Alessandra, Jain, Nitin, others: P371: hyper-CVAD with sequential blinatumomab, with or without inotuzumab ozogamicin, in adults with newly diagnosed philadelphia chromosome-negative B-cell acute lymphoblastic leukemia HemaSphere. 2022; 6 271-272.
Macaron, Walid, Jabbour, Elias, Konopleva, Marina, Ravandi, Farhad, Jain, Nitin, Issa, Ghayas, Kadia, Tapan, Sasaki, Koji, Kebriaei, Partow, Yilmaz, Musa, others: P372: DISMAL OUTCOMES OF PATIENTS WITH RELAPSED/REFRACTORY B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA AFTER FAILURE OF BOTH INOTUZUMAB OZOGAMICIN AND BLINATUMOMAB HemaSphere. 2022; 6 272-273.
Abuasab, T, Mohadam, SF, Hwang, H, Wang, X, Sasaki, K, Yilmaz, M, Kadia, T, DiNardo, C, Daver, N, Pemmaraju, N, others: P496: CLINICAL CHARACTERISTICS OF SECONDARY MYELOID NEOPLASMS IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE HemaSphere. 2022; 6 395-396.
Haddad, Fadi, Sasaki, Koji, Abuasab, Tareq, Venugopal, Sangeetha, Delgado, D Rivera, Bazinet, Alexandre, Babakhanlou, Rodrick, Kim, Kunhwa, Senapati, Jayastu, Ong, Faustine, others: P541: OUTCOMES AND MANAGEMENT OF PATIENTS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA PRESENTING WITH HYPERLEUKOCYTOSIS HemaSphere. 2022; 6 440-441.
Sasaki, K., Mauro, M.J., Levy, M.Y., Atallah, E.L., Koller, P., Maegawa, R., Damon, A., Kumar, J., Khan, M., Cortes, J.E.: CML-433 ASC2ESCALATE Trial in Progress: A Phase 2 Single-Arm Dose Escalation Study of Asciminib Monotherapy in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP) Previously Treated With 1 Prior Tyrosine Kinase Inhibitor (TKI) Clinical Lymphoma, Myeloma and Leukemia. 2022; 22 S299. ( PubMed , DOI )
Koji Sasaki: Phase II study of ponatinib and blinatumomab in Philadelphia chromosome-positive acute lymphoblastic leukemia ANNALS OF ONCOLOGY. 2022; 33 ( DOI )
Koji Sasaki: Phase Ib/2 Study of Oral Decitabine/Cedazuridine (ASTX727) and Venetoclax in Combination with the Targeted Mutant IDH1 Inhibitor Ivosidenib or the Targeted Mutant IDH2 Inhibitor Enasidenib in IDH Mutated Acute Myeloid Leukemia BLOOD. 2022; 140 (Supplement 1): 6170-6172. ( DOI )
Sasaki, Y., Kantarjian, H.M., Short, N.J., Wang, F., Furudate, K., Uryu, H., Garris, R., Jain, N., Sasaki, K., Rav, i, F., Konopleva, M., Garcia-Manero, G., Little, L., Gumbs, C., Zhao, L., Futreal, P.A., Takahashi, K., Jabbour, E.: Correction: Genetic correlates in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with Hyper-CVAD plus dasatinib or ponatinib (Leukemia, (2022), 36, 5, (1253-1260), 10.1038/s41375-021-01496-8) Leukemia. 2022; 36 (5): 1448. ( PubMed , DOI )
Marisa J.L. Aitken, Christopher B. Benton, Ghayas C. Issa, Koji Sasaki, Musa Yilmaz, Nicholas J. Short: Two Cases of Possible Familial Chronic Myeloid Leukemia in a Family with Extensive History of Cancer Acta Haematologica. 2021.09; 144 (5): 585-590. ( PubMed , DOI )
Koji Sasaki: Health Care Resource Utilization (HCRU) with Asciminib and Bosutinib among Patients with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) Previously Treated with ≥2 Tyrosine Kinase Inhibitors (TKIs): Results from the Multicenter, Open-Label Phase 3 ASCEMBL Trial CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2021.09; 21 ( DOI )
Koji Sasaki: Prognostic Value of CRh in Acute Myeloid Leukemia Treated with Venetoclax and Decitabine CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2021.09; 21 S303-S304. ( DOI )
Koji Sasaki: Phase II Study of the IDH2 Inhibitor Enasidenib in Patients with High-Risk IDH2-Mutated Myelodysplastic Syndromes (MDS) CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2021.09; 21 ( DOI )
Haddad, Fadi, Kantarjian, Hagop, Jabbour, Elias J, Issa, Ghayas C, Garcia-Manero, Guillermo, Ravandi, Farhad, Konopleva, Marina, Ferrajoli, Alessandra, Kadia, Tapan M, Pemmaraju, Naveen, others: Treatment-free remission in patients with chronic myeloid leukemia following the discontinuation of tyrosine kinase inhibitors Blood. 2021; 138 1480.
Koji Sasaki: Efficacy and Safety Results From ASCEMBL, a Multicenter, Open-Label, Phase 3 Study of Asciminib, a First-in-Class STAMP Inhibitor, vs Bosutinib in Patients With Chronic Myeloid Leukemia in Chronic Phase Previously Treated With ≥2 Tyrosine Kinase Inhibitors CLINICAL ADVANCES IN HEMATOLOGY & ONCOLOGY. 2021;
Koji Sasaki: Evolutionary action score identifies a subset of TP53 mutated myelodysplastic syndrome with favorable prognosis BLOOD CANCER JOURNAL. 2021; 136 4-5. ( DOI )
Koji Sasaki: Prognostic value of measurable residual disease after venetoclax and decitabine in acute myeloid leukemia BLOOD ADVANCES. 2021; 136 22-25. ( DOI )
Koji Sasaki: Contemporary outcomes for adults with AML requiring ICU admission. JOURNAL OF CLINICAL ONCOLOGY. 2021; ( DOI )
Koji Sasaki: Combined Ibrutinib and Venetoclax for First-Line Treatment of Patients with Chronic Lymphocytic Leukemia (CLL): Focus on Long-Term MRD Results BLOOD. 2021; 138 3720. ( DOI )
Koji Sasaki: Prognostic Relevance of Genetic Abnormalities in Blastic Transformation of Chronic Myeloid Leukemia BLOOD. 2020.11; 136 ( DOI )
Koji Sasaki: Outcomes and Prognostic Scoring System for Elderly Patients with Acute Myeloid Leukemia BLOOD. 2020.11; 136 31-32. ( DOI )
Koji Sasaki: Outcomes of Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia in Molecular Response at Three Months of Therapy CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2020; 20 S164-S165. ( DOI )
Koji Sasaki: Low-Dose Dasatinib 50 mg Daily Versus Standard-Dose Dasatinib 100 mg Daily in Newly Diagnosed Chronic Myeloid Leukemia: A Propensity Score Analysis CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2020; 20 ( DOI )
Koji Sasaki: Only SF3B1 Mutation involving K700E (And Not Other Codons), Independently Predicts Overall Survival in Myelodysplastic Syndromes bioRxiv. 2020; 2020-09. ( DOI )
Bataller, Alex, Kantarjian, Hagop, Bazinet, Alexandre, Kadia, Tapan, Daver, Naval, DiNardo, Courtney D, Borthakur, Gautam, Loghavi, Sanam, Patel, Keyur, Tang, Guilin, others: Outcomes and genetic dynamics of acute myeloid leukemia at first relapse Haematologica. 2020;
Kanagal-Shamanna, Rashmi, Montalban-Bravo, Guillermo, Katsonis, Panagiotis, Sasaki, Koji, Class, Caleb A, Benton, Christopher, Jabbour, Elias, Chien, Kelly S, Luthra, Rajyalakshmi, Bueso-Ramos, Carlos E, others: Evolutionary Action Score of TP53 Mutations: Integrated Clinico-pathologic And Protein Structural Analysis in Myelodysplastic Syndromes bioRxiv. 2020; 2020-07.
佐々木宏治: CML 治療と予後の最前線 臨床血液. 2020;
Koji Sasaki: Clarifying the structure of serious head and spine injury in youth Rugby Union players Plos One. 2020; ( DOI )
Koji Sasaki: Clinical Course, Outcomes and Genetic Characterization of Patients with Isolated Myeloid Sarcoma BLOOD. 2020; 136 25-26. ( DOI )
Bravo, Guillermo Montalban, Kanagal-Shamanna, Rashmi, Sasaki, Koji, Masarova, Lucia, Naqvi, Kiran, Jabbour, Elias, DiNardo, Courtney D, Takahashi, Koichi, Konopleva, Marina, Pemmaraju, Naveen, others: Clinicopathologic Correlates and Natural History of Atypical Chronic Myeloid Leukemia Blood. 2020; 136 54-56. ( PubMed , DOI )
DiNardo, Courtney D, Maiti, Abhishek, Rausch, Caitlin R, Pemmaraju, Naveen, Naqvi, Kiran, Daver, Naval G, Kadia, Tapan M, Borthakur, Gautam, Ohanian, Maro, Alvarado, Yesid, others: Ten-day decitabine with venetoclax in acute myeloid leukemia: a single-arm phase 2 trial The Lancet. Haematology. 2020; 7 (10):
Kelly Sharon Chien, Caleb A. Class, Guillermo Montalban-Bravo, Koji Sasaki, Kiran Naqvi, Irene Ganan Gomez, Yue Wei, Hui Yang, Rashmi Kanagal-Shamanna, Hagop M. Kantarjian, Guillermo Garcia-Manero: LILRB4 expression in CMML and MDS based on response to hypomethylating agents. Journal of Clinical Oncology. 2019.05; 37 (15_suppl): ( DOI )
Koji Sasaki: Association of smoking with poor risk ELN 2017, cytogenetics/molecular profile, and survival outcomes in acute myeloid leukemia. JOURNAL OF CLINICAL ONCOLOGY. 2019;
Koji Sasaki: Dynamic Prediction of Outcome with Longitudinal BCR-ABL1 Levels in Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019; 19 S180-S181. ( DOI )
Koji Sasaki: Duplex Sequencing Identifies Low Level ABL1 Kinase Domain Mutations in Untreated Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019; 19 ( DOI )
Koji Sasaki: Reduced-Intensity Chemotherapy Plus Inotuzumab Ozogamicin, With or Without Sequential Blinatumomab, is Highly Effective as First Salvage Treatment in Patients with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019; 19 S186-S187. ( DOI )
Koji Sasaki: The Impact of Smoking on Relapse and Survival in Patients with Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Treated with the Combination of Intensive Therapy with Tyrosine Kinase Inhibitor CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. 2019; 19 ( DOI )
Koji Sasaki: Efficacy and Safety of Romiplostim in Patients with Acquired Aplastic Anemia Ineligible or Refractory to Immunosuppressive Therapy: Interim Analysis of Phase 2/3 Clinical Trial BLOOD. 2018.11; 132 ( DOI )
Garcia-Manero, Guillermo, Montalban-Bravo, Guillermo, Sasaki, Koji, Daver, Naval G, Jabbour, Elias J, Alvarado, Yesid, DiNardo, Courtney D, Ravandi, Farhad, Borthakur, Gautam, Bose, Prithviraj, others: Double immune checkpoint inhibitor blockade with nivolumab and ipilimumab with or without azacitidine in patients with myelodysplastic syndrome (MDS) Blood. 2018.11; 132 (Supplement 1): 1831. ( DOI )
Sasaki, Koji, Kantarjian, Hagop M, Ravandi, Farhad, Konopleva, Marina Y, Borthakur, Gautam, Garcia-Manero, Guillermo, Wierda, William G, Daver, Naval G, Ferrajoli, Alessandra, Takahashi, Koichi, others: Dynamic Personalized Assessment in Patients with Chronic Myeloid Leukemia in Chronic Phase Blood. 2018.11; 132 (Supplement 1): 3026. ( DOI )
Koji Sasaki: INOTUZUMAB OZOGAMICIN IN COMBINATION WITH LOW-INTENSITY CHEMOTHERAPY (MINI-HYPER-CVD) AS FRONTLINE THERAPY FOR OLDER PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA: UPDATED RESULTS FROM A PHASE I/II TRIAL HAEMATOLOGICA. 2017;
Koji Sasaki: Survival Outcome of Secondary Solid Cancer in Patients with Chronic Myeloid Leukemia BLOOD. 2017; 130 1623.
Koji Sasaki: A RANDOMIZED PHASE II STUDY OF IDARUBICIN AND CYTARABINE WITH EITHER CLOFARABINE OR FLUDARABINE IN ADULTS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA HAEMATOLOGICA. 2017;
Koji Sasaki: Updated Results of the Phase II Trial of Inotuzumab Ozogamicin (INO) Combined with Mini-Hyper-CVD As Salvage Therapy for Relapsed/Refractory (R/R) B-Cell Acute Lymphoblastic Leukemia (B-ALL) BLOOD. 2017; 130 (Supplement 1): 2597.
Koji Sasaki: UPDATED RESULTS OF A PHASE II STUDY OF HYPER-CVAD PLUS PONATINIB AS FRONTLINE THERAPY FOR ADULTS WITH PHILADELPHIA CHROMOSOME-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA HAEMATOLOGICA. 2017;