Lihong Cheng, Caiyue Shi, Xixi Li, Toshiro Matsui: Impact of Peptide Transport and Memory Function in the Brain Nutrients. 2024.09; ( DOI )
Cryo-electron tomography of the actin cytoskeleton and membrane organization during lamellipodia formation using optogenetics 2024.08; ( DOI )
Cheng L, Shi C, Nakamura S, Esaki N, Ichiba Y, Tanaka M, Sakai K, Matsui T: Adiponectin-Receptor Agonistic Dipeptide Tyr-Pro Stimulates the Acetylcholine Nervous System in NE-4C Cells. Journal of agricultural and food chemistry. 2024.04; 72 (13): 7121-7129. ( PubMed , DOI )
Toshifumi Asano, Philipp Sasse, Takao Nakata: Development of a Cre-recombination-based color-switching reporter system for cell fusion detection. Biochem Biophys Res Commun. 2024.01; 690 149231. ( PubMed , DOI )
Aiko Takada, Toshifumi Asano, Ken-Ichi Nakahama, Takashi Ono, Takao Nakata, Tomohiro Ishii: Development of an optogenetics tool, Opto-RANK, for control of osteoclast differentiation using blue light. Sci Rep. 2024.01; 14 (1): 1749. ( PubMed , DOI )
Cheng L, Tanaka M, Yoshino A, Nagasato Y, Takata F, Dohgu S, Matsui T: A memory-improving dipeptide, Tyr-Pro, can reach the mouse brain after oral administration. Scientific reports. 2023.10; 13 (1): 16908. ( PubMed , DOI )
Yoshimi Arima, Satoko Matsueda, Hideyuki Saya: Significance of Cancer-Associated Fibroblasts in the Interactions of Cancer Cells with the Tumor Microenvironment of Heterogeneous Tumor Tissue. Cancers (Basel). 2023.04; 15 (9): ( PubMed , DOI )
Haruki Inoue, Eriko Aimono, Akiyoshi Kasuga, Haruto Tanaka, Aika Iwasaki, Hideyuki Saya, Yoshimi Arima: Pixel-Level Clustering of Hematoxylin-Eosin-Stained Sections of Mouse and Human Biliary Tract Cancer. Biomedicines. 2022.12; 10 (12): ( PubMed , DOI )
Ritsuko Harigai, Ryo Sato, Chikako Hirose, Toshiki Takenouchi, Kenjiro Kosaki, Takanori Hirose, Hideyuki Saya, Yoshimi Arima: Mutation of PTPN11 (Encoding SHP-2) Promotes MEK Activation and Malignant Progression in Neurofibromin-Deficient Cells in a Manner Sensitive to BRAP Mutation. Cancers (Basel). 2022.05; 14 (10): ( PubMed , DOI )
Ryo Sato, Kosuke Imamura, Takashi Semba, Yusuke Tomita, Sho Saeki, Koei Ikeda, Yoshihiro Komohara, Makoto Suzuki, Takuro Sakagami, Hideyuki Saya, Yoshimi Arima: TGFβ Signaling Activated by Cancer-Associated Fibroblasts Determines the Histological Signature of Lung Adenocarcinoma. Cancer Res. 2021.09; 81 (18): 4751-4765. ( PubMed , DOI )
Tomoya Uchimura, Toshifumi Asano, Takao Nakata, Akitsu Hotta, Hidetoshi Sakurai: A muscle fatigue-like contractile decline was recapitulated using skeletal myotubes from Duchenne muscular dystrophy patient-derived iPSCs. Cell Reports Medicine. 2021.06; 2 (6): 100298. ( PubMed , DOI )
Akiyoshi Kasuga, Takashi Semba, Ryo Sato, Hiroyuki Nobusue, Eiji Sugihara, Hiromasa Takaishi, Takanori Kanai, Hideyuki Saya, Yoshimi Arima: Oncogenic KRAS-expressing organoids with biliary epithelial stem cell properties give rise to biliary tract cancer in mice. Cancer Sci. 2021.05; 112 (5): 1822-1838. ( PubMed , DOI )
Shogo Yoshihara , Xuguang Jiang , Momo Morikawa , Tadayuki Ogawa , Sotaro Ichinose , Hirooki Yabe , Akiyoshi Kakita , Manabu Toyoshima , Yasuto Kunii , Takeo Yoshikawa , Yosuke Tanaka , Nobutaka Hirokawa : Betaine ameliorates schizophrenic traits by functionally compensating for KIF3-based CRMP2 transport Cell Reports. 2021.04; 35 (2): 108971. ( PubMed , DOI )
Hironori Inaba, Qianqian Miao, Takao Nakata: Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling. J Biol Chem. 2021.01; 100290. ( PubMed , DOI )
Takashi Semba, Ryo Sato, Akiyoshi Kasuga, Kentaro Suina, Tatsuhiro Shibata, Takashi Kohno, Makoto Suzuki, Hideyuki Saya, Yoshimi Arima: Lung Adenocarcinoma Mouse Models Based on Orthotopic Transplantation of Syngeneic Tumor-Initiating Cells Expressing EpCAM, SCA-1, and Ly6d. Cancers (Basel). 2020.12; 12 (12): ( PubMed , DOI )
Mari Hosonaga, Hideyuki Saya, Yoshimi Arima: Molecular and cellular mechanisms underlying brain metastasis of breast cancer. Cancer Metastasis Rev. 2020.09; 39 (3): 711-720. ( PubMed , DOI )
Takanobu Shimizu, Takeshi Nakamura, Hironori Inaba, Hiroaki Iwasa, Junichi Maruyama, Kyoko Arimoto-Matsuzaki, Takao Nakata, Hiroshi Nishina, Yutaka Hata: The RAS-interacting chaperone UNC119 drives the RASSF6-MDM2-p53 axis and antagonizes RAS-mediated malignant transformation. J. Biol. Chem.. 2020.08; 295 (32): 11214-11230. ( PubMed , DOI )
Yoshimi Arima, Hiroyuki Nobusue, Hideyuki Saya: Targeting of cancer stem cells by differentiation therapy. Cancer Sci. 2020.08; 111 (8): 2689-2695. ( PubMed , DOI )
Xiang, L; Wu, QB; Cheng, LH; Sun, KY; Li, J; Yoshida, M; Qi, JH: Leptin and Adiponectin Signaling Pathways Are Involved in the Antiobesity Effects of Peanut Skin Extract OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2019.10; 2019 1-14. ( PubMed , DOI )
Manabu Toyoshima,Xuguang Jiang, Tadayuki Ogawa, Tetsuo Ohnishi, Shogo Yoshihara, Shabeesh Balan, Takeo Yoshikawa, Nobutaka Hirokawa: Enhanced carbonyl stress induces irreversible multimerization of CRMP2 in schizophrenia pathogenesis Life Science Alliance. 2019.10; 2 (5): lsa.201900478. ( PubMed , DOI )
Moe Sato, Toshifumi Asano, Jun Hosomichi, Takashi Ono, Takao Nakata: Optogenetic manipulation of intracellular calcium by BACCS promotes differentiation of MC3T3-E1 cells. Biochemical and Biophysical Research Communications. 2018.11; 506 (3): 716-722. ( PubMed , DOI )
Bian, LL; Cao, SN; Cheng, LH; Nakazaki, A; Nishikawa, T; Qi, JH: Semi-synthesis and Structure-Activity Relationship of Neuritogenic Oleanene Derivatives CHEMMEDCHEM. 2018.09; 13 (18): 1972-1977. ( PubMed , DOI )
Qi, JH; Cheng, LH; Sun, YJ; Hirata, Y; Ushida, N; Ma, ZH; Osada, H; Nishikawa, T; Xiang, L: Identification of an Asexual Reproduction Inducer of Phytopathogenic and Toxigenic Fusarium ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2018.07; 57 (27): 8100-8104. ( PubMed , DOI )
Mari Hosonaga, Yoshimi Arima, Oltea Sampetrean, Daisuke Komura, Ikuko Koya, Takashi Sasaki, Eiichi Sato, Hideyuki Okano, Jun Kudoh, Shumpei Ishikawa, Hideyuki Saya, Takashi Ishikawa: HER2 Heterogeneity Is Associated with Poor Survival in HER2-Positive Breast Cancer. Int J Mol Sci. 2018.07; 19 (8): ( PubMed , DOI )
T Ouchi, S Morikawa, S Shibata, M Takahashi, M Yoshikawa, T Soma, H Miyashita, W Muraoka, K Kameyama, H Kawana, Y Arima, H Saya, H Okano, T Nakagawa, S Asoda: Recurrent Spindle Cell Carcinoma Shows Features of Mesenchymal Stem Cells. J Dent Res. 2018.07; 97 (7): 779-786. ( PubMed , DOI )
Zhang, H; Farooq, U; Cheng, LH; Ye, Y; Wang, YC; Kawagishi, H; Ojika, M; Qi, JH: Specific Inhibitors of Sporangium Formation of Phytophthora capsici from Kalimeris indica CHEMISTRY OF NATURAL COMPOUNDS. 2018.05; 54 (3): 567-569. ( DOI )
Takashi Semba, Eiji Sugihara, Nagisa Kamoshita, Sayaka Ueno, Keitaro Fukuda, Masafumi Yoshino, Kazumasa Takao, Kazunori Yoshikawa, Kenji Izuhara, Yoshimi Arima, Makoto Suzuki, Hideyuki Saya: Periostin antisense oligonucleotide suppresses bleomycin-induced formation of a lung premetastatic niche for melanoma. Cancer Sci. 2018.05; 109 (5): 1447-1454. ( PubMed , DOI )
Ritsuko Harigai, Shigeki Sakai, Hiroyuki Nobusue, Chikako Hirose, Oltea Sampetrean, Noriaki Minami, Yukie Hata, Takashi Kasama, Takanori Hirose, Toshiki Takenouchi, Kenjiro Kosaki, Kazuo Kishi, Hideyuki Saya, Yoshimi Arima: Tranilast inhibits the expression of genes related to epithelial-mesenchymal transition and angiogenesis in neurofibromin-deficient cells. Sci Rep. 2018.04; 8 (1): 6069. ( PubMed , DOI )
Yuji Otsuki, Hideyuki Saya, Yoshimi Arima: Prospects for new lung cancer treatments that target EMT signaling. Dev Dyn. 2018.03; 247 (3): 462-472. ( PubMed , DOI )
Noriaki Minami, Yusuke Maeda, Shunsuke Shibao, Yoshimi Arima, Fumiharu Ohka, Yutaka Kondo, Koji Maruyama, Masatoshi Kusuhara, Takashi Sasayama, Eiji Kohmura, Hideyuki Saya, Oltea Sampetrean: Organotypic brain explant culture as a drug evaluation system for malignant brain tumors. Cancer Med. 2017.11; 6 (11): 2635-2645. ( PubMed , DOI )
Takashi Semba, Yoshimi Arima: Epithelial-mesenchymal transition is predetermined by the epigenetic state of the skin tumor cell of origin. Stem Cell Investig. 2017; 4 37. ( PubMed , DOI )
Ryo Sato, Teppei Nakano, Mari Hosonaga, Oltea Sampetrean, Ritsuko Harigai, Takashi Sasaki, Ikuko Koya, Hideyuki Okano, Jun Kudoh, Hideyuki Saya, Yoshimi Arima: RNA Sequencing Analysis Reveals Interactions between Breast Cancer or Melanoma Cells and the Tissue Microenvironment during Brain Metastasis. Biomed Res Int. 2017; 2017 8032910. ( PubMed , DOI )
Yayoi Takamoto, Yoshimi Arima, Hideyuki Saya: Development of mouse models of malignant phyllodes tumors by transplantation of syngeneic mammary gland cells expressing mutant H-Ras. Genes Cells. 2016.11; 21 (11): 1244-1252. ( PubMed , DOI )
Ryo Sato, Takashi Semba, Hideyuki Saya, Yoshimi Arima: Concise Review: Stem Cells and Epithelial-Mesenchymal Transition in Cancer: Biological Implications and Therapeutic Targets. Stem Cells. 2016.08; 34 (8): 1997-2007. ( PubMed , DOI )
Kazuhiro Umeyama, Kota Watanabe, Masahito Watanabe, Keisuke Horiuchi, Kazuaki Nakano, Masateru Kitashiro, Hitomi Matsunari, Tokuhiro Kimura, Yoshimi Arima, Oltea Sampetrean, Masaki Nagaya, Masahiro Saito, Hideyuki Saya, Kenjiro Kosaki, Hiroshi Nagashima, Morio Matsumoto: Generation of heterozygous fibrillin-1 mutant cloned pigs from genome-edited foetal fibroblasts. Sci Rep. 2016.04; 6 24413. ( PubMed , DOI )
Maruoka R, Takenouchi T, Torii C, Shimizu A, Misu K, Higasa K, Matsuda F, Ota A, Tanito K, Kuramochi A, Arima Y, Otsuka F, Yoshida Y, Moriyama K, Niimura M, Saya H, Kosaki K: The use of next-generation sequencing in molecular diagnosis of neurofibromatosis type 1: a validation study. Genet Test Mol Biomarkers. 2014.11; 18 (11): 722-735. ( PubMed , DOI )
Mari Hosonaga, Yoshimi Arima, Eiji Sugihara, Norio Kohno, Hideyuki Saya: Expression of CD24 is associated with HER2 expression and supports HER2-Akt signaling in HER2-positive breast cancer cells. Cancer Sci. 2014.07; 105 (7): 779-787. ( PubMed , DOI )
K Kai, T Iwamoto, T Kobayashi, Y Arima, Y Takamoto, N Ohnishi, C Bartholomeusz, R Horii, F Akiyama, G N Hortobagyi, L Pusztai, H Saya, N T Ueno: Ink4a/Arf(-/-) and HRAS(G12V) transform mouse mammary cells into triple-negative breast cancer containing tumorigenic CD49f(-) quiescent cells. Oncogene. 2014.01; 33 (4): 440-448. ( PubMed , DOI )
Takaaki M Goto, Yoshimi Arima, Osamu Nagano, Hideyuki Saya: Lysyl oxidase is induced by cell density-mediated cell cycle suppression via RB-E2F1-HIF-1α axis. Cell Struct Funct. 2013; 38 (1): 9-14. ( PubMed , DOI )
Toshiyuki Kakumoto, Takao Nakata: Optogenetic control of PIP3: PIP3 is sufficient to induce the actin-based active part of growth cones and is regulated via endocytosis. PLoS ONE. 2013; 8 (8): e70861. ( PubMed , DOI )
Yoshimi Arima, Naoki Hayashi, Hidemi Hayashi, Mikako Sasaki, Kazuharu Kai, Eiji Sugihara, Eriko Abe, Atsushi Yoshida, Shuji Mikami, Seigo Nakamura, Hideyuki Saya: Loss of p16 expression is associated with the stem cell characteristics of surface markers and therapeutic resistance in estrogen receptor-negative breast cancer. Int J Cancer. 2012.06; 130 (11): 2568-2579. ( PubMed , DOI )
Tatsuyuki Chiyoda, Naoyuki Sugiyama, Takatsune Shimizu, Hideaki Naoe, Yusuke Kobayashi, Jo Ishizawa, Yoshimi Arima, Hiroshi Tsuda, Masaaki Ito, Kozo Kaibuchi, Daisuke Aoki, Yasushi Ishihama, Hideyuki Saya, Shinji Kuninaka: LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression. J Cell Biol. 2012.05; 197 (5): 625-641. ( PubMed , DOI )
Yoshimi Arima, Hidemi Hayashi, Mikako Sasaki, Mari Hosonaga, Takaaki M Goto, Tatsuyuki Chiyoda, Shinji Kuninaka, Tatsuhiro Shibata, Hirokazu Ohata, Hitoshi Nakagama, Yoichi Taya, Hideyuki Saya: Induction of ZEB proteins by inactivation of RB protein is key determinant of mesenchymal phenotype of breast cancer. J Biol Chem. 2012.03; 287 (11): 7896-7906. ( PubMed , DOI )
Yoshimi Arima, Hidemi Hayashi, Kanako Kamata, Takaaki M Goto, Mikako Sasaki, Akira Kuramochi, Hideyuki Saya: Decreased expression of neurofibromin contributes to epithelial-mesenchymal transition in neurofibromatosis type 1. Exp Dermatol. 2010.08; 19 (8): e136-e141. ( PubMed , DOI )
Kazuharu Kai, Yoshimi Arima, Toshio Kamiya, Hideyuki Saya: Breast cancer stem cells. Breast Cancer. 2010.04; 17 (2): 80-85. ( PubMed , DOI )
Kazuharu Kai, Osamu Nagano, Eiji Sugihara, Yoshimi Arima, Oltea Sampetrean, Takatsugu Ishimoto, Masaya Nakanishi, Naoto T Ueno, Hirotaka Iwase, Hideyuki Saya: Maintenance of HCT116 colon cancer cell line conforms to a stochastic model but not a cancer stem cell model. Cancer Sci. 2009.12; 100 (12): 2275-2282. ( PubMed , DOI )
Yoshimi Arima, Yasumichi Inoue, Tatsuhiro Shibata, Hidemi Hayashi, Osamu Nagano, Hideyuki Saya, Yoichi Taya: Rb depletion results in deregulation of E-cadherin and induction of cellular phenotypic changes that are characteristic of the epithelial-to-mesenchymal transition. Cancer Res. 2008.07; 68 (13): 5104-5112. ( PubMed , DOI )
Christian Bronner, Mayada Achour, Yoshimi Arima, Thierry Chataigneau, Hideyuki Saya, Valérie B Schini-Kerth: The UHRF family: oncogenes that are drugable targets for cancer therapy in the near future? Pharmacol Ther. 2007.09; 115 (3): 419-434. ( PubMed , DOI )
S Kuninaka, S-I Iida, T Hara, M Nomura, H Naoe, T Morisaki, M Nitta, Y Arima, T Mimori, S Yonehara, H Saya: Serine protease Omi/HtrA2 targets WARTS kinase to control cell proliferation. Oncogene. 2007.04; 26 (17): 2395-2406. ( PubMed , DOI )
Yoshihiro Komohara, Mamoru Harada, Yoshimi Arima, Shigetaka Suekane, Masanori Noguchi, Akira Yamada, Kyogo Itoh, Kei Matsuoka: Identification of target antigens in specific immunotherapy for renal cell carcinoma. J Urol. 2007.03; 177 (3): 1157-1162. ( PubMed , DOI )
Takao Nakata, Nobutaka Hirokawa: Neuronal polarity and the kinesin superfamily proteins. Sci. STKE. 2007.02; 2007 (372): pe6. ( PubMed , DOI )
Yoshihiro Komohara, Mamoru Harada, Yoshimi Arima, Shigetaka Suekane, Masanori Noguchi, Akira Yamada, Kyogo Itoh, Kei Matsuoka: Anti-cancer vaccine candidates in specific immunotherapy for bladder carcinoma. Int J Oncol. 2006.12; 29 (6): 1555-1560. ( PubMed )
Yoshimi Arima, Satoko Matsueda, Hirohisa Yano, Mamoru Harada, Kyogo Itoh: Parathyroid hormone-related protein as a common target molecule in specific immunotherapy for a wide variety of tumor types. Int J Oncol. 2005.10; 27 (4): 981-988. ( PubMed )
Naoki Yajima, Ryuya Yamanaka, Takashi Mine, Naoto Tsuchiya, Jumpei Homma, Masakazu Sano, Terukazu Kuramoto, Yayoi Obata, Nobukazu Komatsu, Yoshimi Arima, Akira Yamada, Minoru Shigemori, Kyogo Itoh, Ryuichi Tanaka: Immunologic evaluation of personalized peptide vaccination for patients with advanced malignant glioma. Clin Cancer Res. 2005.08; 11 (16): 5900-5911. ( PubMed , DOI )
Shinji Kuninaka, Masanobu Nomura, Toru Hirota, Shin-Ichi Iida, Toshihiro Hara, Shinobu Honda, Naoko Kunitoku, Takashi Sasayama, Yoshimi Arima, Tomotoshi Marumoto, Kageharu Koja, Shin Yonehara, Hideyuki Saya: The tumor suppressor WARTS activates the Omi / HtrA2-dependent pathway of cell death. Oncogene. 2005.08; 24 (34): 5287-5298. ( PubMed , DOI )
Yoshimi Arima, Masayuki Nitta, Shinji Kuninaka, Dongwei Zhang, Toshiyoshi Fujiwara, Yoichi Taya, Mitsuyoshi Nakao, Hideyuki Saya: Transcriptional blockade induces p53-dependent apoptosis associated with translocation of p53 to mitochondria. J Biol Chem. 2005.05; 280 (19): 19166-19176. ( PubMed , DOI )
Junlin Teng, Tatemitsu Rai, Yosuke Tanaka, Yosuke Takei, Takao Nakata, Motoyuki Hirasawa, Ashok B Kulkarni, Nobutaka Hirokawa: The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium. Nat. Cell Biol.. 2005.05; 7 (5): 474-482. ( PubMed , DOI )
Yi Wang, Mamoru Harada, Hirohisa Yano, Sachiko Ogasawara, Hiroko Takedatsu, Yoshimi Arima, Satoko Matsueda, Akira Yamada, Kyogo Itoh: Prostatic acid phosphatase as a target molecule in specific immunotherapy for patients with nonprostate adenocarcinoma. J Immunother. 2005; 28 (6): 535-541. ( PubMed , DOI )
Dongwei Zhang, Toru Hirota, Tomotoshi Marumoto, Michio Shimizu, Naoko Kunitoku, Takashi Sasayama, Yoshimi Arima, Liping Feng, Misao Suzuki, Motohiro Takeya, Hideyuki Saya: Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models. Oncogene. 2004.11; 23 (54): 8720-8730. ( PubMed , DOI )
Shinobu Honda, Tomotoshi Marumoto, Toru Hirota, Masayuki Nitta, Yoshimi Arima, Michio Ogawa, Hideyuki Saya: Activation of m-calpain is required for chromosome alignment on the metaphase plate during mitosis. J Biol Chem. 2004.03; 279 (11): 10615-10623. ( PubMed , DOI )
Yoshimi Arima, Toru Hirota, Christian Bronner, Marc Mousli, Toshiyoshi Fujiwara, Shin-ichiro Niwa, Hiroyuki Ishikawa, Hideyuki Saya: Down-regulation of nuclear protein ICBP90 by p53/p21Cip1/WAF1-dependent DNA-damage checkpoint signals contributes to cell cycle arrest at G1/S transition. Genes Cells. 2004.02; 9 (2): 131-142. ( PubMed , DOI )
Takao Nakata, Nobutaka Hirokawa: Microtubules provide directional cues for polarized axonal transport through interaction with kinesin motor head. J. Cell Biol.. 2003.09; 162 (6): 1045-1055. ( PubMed , DOI )
Homma N, Takei Y, Tanaka Y, Nakata T, Terada S, Kikkawa M, Noda Y, Hirokawa N.: Kinesin superfamily protein 2A (KIF2A) functions in suppression of collateral branch extension Cell. 2003.07; 114 (2): 229-239. ( PubMed , DOI )
Ying Xu, Sen Takeda, Takao Nakata, Yasuko Noda, Yosuke Tanaka, Nobutaka Hirokawa: Role of KIFC3 motor protein in Golgi positioning and integration. J. Cell Biol.. 2002.07; 158 (2): 293-303. ( PubMed , DOI )
Kazuo Nakajima, Yosuke Takei, Yosuke Tanaka, Terunaga Nakagawa, Takao Nakata, Yasuko Noda, Mitsutoshi Setou, Nobutaka Hirokawa: Molecular motor KIF1C is not essential for mouse survival and motor-dependent retrograde Golgi apparatus-to-endoplasmic reticulum transport. Mol. Cell. Biol.. 2002.02; 22 (3): 866-873. ( PubMed )
Masayuki Nitta, Hiromasa Tsuiki, Yoshimi Arima, Kei Harada, Takahumi Nishizaki, Kousuke Sasaki, Tatsuyuki Mimori, Yukitaka Ushio, Hideyuki Saya: Hyperploidy induced by drugs that inhibit formation of microtubule promotes chromosome instability. Genes Cells. 2002.02; 7 (2): 151-162. ( PubMed , DOI )
J Teng, Y Takei, A Harada, T Nakata, J Chen, N Hirokawa: Synergistic effects of MAP2 and MAP1B knockout in neuronal migration, dendritic outgrowth, and microtubule organization. J. Cell Biol.. 2001.10; 155 (1): 65-76. ( PubMed , DOI )
Zhao C, Takita J, Tanaka Y, Setou M, Nakagawa T, Takeda S, Yang HW, Terada S, Nakata T, Takei Y, Saito M, Tsuji S, Hayashi Y, Hirokawa N.: Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta Cell. 2001.06; 105 (5): 587-597. ( PubMed , DOI )
J Chen, T Nakata, Z Zhang, N Hirokawa: The C-terminal tail domain of neurofilament protein-H (NF-H) forms the crossbridges and regulates neurofilament bundle formation. J. Cell. Sci.. 2000.11; 113 Pt 21 3861-3869. ( PubMed )
Nakata T, Terada S, Hirokawa N.: Visualization of the dynamics of synaptic vesicle and plasma membrane proteins in living axons Journal of Cell Biology. 1998.02; 140 (3): 659-674. ( PubMed , DOI )
K i Nagata, A Puls, C Futter, P Aspenstrom, E Schaefer, T Nakata, N Hirokawa, A Hall: The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3. EMBO J.. 1998.01; 17 (1): 149-158. ( PubMed , DOI )
H Yamazaki, T Nakata, Y Okada, N Hirokawa: Cloning and characterization of KAP3: a novel kinesin superfamily-associated protein of KIF3A/3B. Proc. Natl. Acad. Sci. U.S.A.. 1996.08; 93 (16): 8443-8448. ( PubMed )
Terada S, Nakata T, Peterson AC, Hirokawa N.: Visualization of slow axonal transport in vivo Science. 1996.08; 273 (5276): 784-788. ( PubMed , DOI )
R Takemura, T Nakata, Y Okada, H Yamazaki, Z Zhang, N Hirokawa: mRNA expression of KIF1A, KIF1B, KIF2, KIF3A, KIF3B, KIF4, KIF5, and cytoplasmic dynein during axonal regeneration. J. Neurosci.. 1996.01; 16 (1): 31-35. ( PubMed )
T Nakata, N Hirokawa: Point mutation of adenosine triphosphate-binding motif generated rigor kinesin that selectively blocks anterograde lysosome membrane transport. J. Cell Biol.. 1995.11; 131 (4): 1039-1053. ( PubMed )
H Yamazaki, T Nakata, Y Okada, N Hirokawa: KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport. J. Cell Biol.. 1995.09; 130 (6): 1387-1399. ( PubMed )
M Kikkawa, T Ishikawa, T Nakata, T Wakabayashi, N Hirokawa: Direct visualization of the microtubule lattice seam both in vitro and in vivo. J. Cell Biol.. 1994.12; 127 (6 Pt 2): 1965-1971. ( PubMed )
T Hayashi, F Soulie, T Nakata, N Hirokawa: Redistribution of synapsin I and synaptophysin in response to electrical stimulation in the rat neurohypophysial nerve endings. Cell Struct. Funct.. 1994.08; 19 (4): 253-262. ( PubMed )
A Ando, K Yonezawa, I Gout, T Nakata, H Ueda, K Hara, Y Kitamura, Y Noda, T Takenawa, N Hirokawa: A complex of GRB2-dynamin binds to tyrosine-phosphorylated insulin receptor substrate-1 after insulin treatment. EMBO J.. 1994.07; 13 (13): 3033-3038. ( PubMed )
S Kondo, R Sato-Yoshitake, Y Noda, H Aizawa, T Nakata, Y Matsuura, N Hirokawa: KIF3A is a new microtubule-based anterograde motor in the nerve axon. J. Cell Biol.. 1994.06; 125 (5): 1095-1107. ( PubMed )
H Miki, K Miura, K Matuoka, T Nakata, N Hirokawa, S Orita, K Kaibuchi, Y Takai, T Takenawa: Association of Ash/Grb-2 with dynamin through the Src homology 3 domain. J. Biol. Chem.. 1994.02; 269 (8): 5489-5492. ( PubMed )
T Nakata, R Sato-Yoshitake, Y Okada, Y Noda, N Hirokawa: Thermal drift is enough to drive a single microtubule along its axis even in the absence of motor proteins. Biophys. J.. 1993.12; 65 (6): 2504-2510. ( PubMed , DOI )
Z Zhang, Y Tanaka, S Nonaka, H Aizawa, H Kawasaki, T Nakata, N Hirokawa: The primary structure of rat brain (cytoplasmic) dynein heavy chain, a cytoplasmic motor enzyme. Proc. Natl. Acad. Sci. U.S.A.. 1993.09; 90 (17): 7928-7932. ( PubMed )
Y Noda, T Nakata, N Hirokawa: Localization of dynamin: widespread distribution in mature neurons and association with membranous organelles. Neuroscience. 1993.07; 55 (1): 113-127. ( PubMed )
T Nakata, R Takemura, N Hirokawa: A novel member of the dynamin family of GTP-binding proteins is expressed specifically in the testis. J. Cell. Sci.. 1993.05; 105 ( Pt 1) 1-5. ( PubMed )
T. Nakata and N. Hirokawa. : Is dynamin GTPase a microtubule based motor? Neuronal Cytoskeleton. 1993; 285-303.
Y Tanaka, K Kawahata, T Nakata, N Hirokawa: Chronological expression of microtubule-associated proteins (MAPs) in EC cell P19 after neuronal induction by retinoic acid. Brain Res.. 1992.11; 596 (1-2): 269-278. ( PubMed )
K Maeda, T Nakata, Y Noda, R Sato-Yoshitake, N Hirokawa: Interaction of dynamin with microtubules: its structure and GTPase activity investigated by using highly purified dynamin. Mol. Biol. Cell. 1992.10; 3 (10): 1181-1194. ( PubMed )
T Nakata, N Hirokawa: Organization of cortical cytoskeleton of cultured chromaffin cells and involvement in secretion as revealed by quick-freeze, deep-etching, and double-label immunoelectron microscopy. J. Neurosci.. 1992.06; 12 (6): 2186-2197. ( PubMed )
T Nakata, A Iwamoto, Y Noda, R Takemura, H Yoshikura, N Hirokawa: Predominant and developmentally regulated expression of dynamin in neurons. Neuron. 1991.09; 7 (3): 461-469. ( PubMed )
T Nakata, K Sobue, N Hirokawa: Conformational change and localization of calpactin I complex involved in exocytosis as revealed by quick-freeze, deep-etch electron microscopy and immunocytochemistry. J. Cell Biol.. 1990.01; 110 (1): 13-25. ( PubMed )
T Nakata, N Hirokawa: Cytoskeletal reorganization of human platelets after stimulation revealed by the quick-freeze deep-etch technique. J. Cell Biol.. 1987.10; 105 (4): 1771-1780. ( PubMed )
稲葉 弘哲, 中田 隆夫: 低分子量Gタンパク質の光遺伝学による操作と細胞内機能の観察 顕微鏡. 2021.08; 56 (2): 59-63. ( DOI )
豊島 学, 蒋 緒光, 小川 覚之, 大西 哲生, 吉原 壯悟, Balan Shabeesh, 廣川 信隆, 吉川 武男: カルボニルストレスによる神経発達異常のタンパク質分子病態解析 日本神経精神薬理学会年会・日本生物学的精神医学会年会・日本精神薬学会総会・学術集会合同年会プログラム・抄録集. 2020.08; 50回・42回・4回 190.
酒井 成貴, 有馬 好美, 坂本 好昭, 中島 由佳理, 佐谷 秀行, 貴志 和生: 【神経線維腫症1型(Recklinghausen病)の病態と治療:小児外科医のかかわり・役割】び漫性神経線維腫(diffuse neurofibroma)に対する外科治療 小児外科. 2019.12; 51 (12): 1184-1187. ( 医中誌 )
木村 聖美, 有馬 好美: 【乳癌のすべて】診断・治療の進歩 治療戦略を考えるうえでのLuminal/HER2乳癌の基礎 医学のあゆみ. 2017.04; 261 (5): 463-468. ( 医中誌 )
有馬 好美, 佐藤 亮: 【発がん 遺伝子変異+αの真実に迫る タール癌から1世紀を超え、いま紐解かれる複雑性】転写因子による上皮間葉転換の制御とがん幹細胞 実験医学. 2016.09;
石井 智浩, 中田 隆夫: 光スイッチによる細胞内Ca2+シグナル制御 実験医学. 2016.03; 34 (4): 601-606.
細永真理, 有馬好美, 佐谷秀行: 乳がん幹細胞~HER2シグナルに関する新たな知見~ 腫瘍内科. 2014.09; 14 (3): 281-287.
中田隆夫: シグナル分子の光制御技術と神経の形態形成 ブレインサイエンス・レビュー2011(伊藤正男・川合述史編). 2011.03; 23-36.
有馬 好美, 佐谷 秀行: 【乳癌のバイオロジーと臨床 診断と治療への応用】乳癌におけるRb不活化と上皮間葉転換について 乳癌の臨床. 2011.02;
有馬 好美, 神谷 敏夫, 佐谷 秀行: 【がん転移 臨床と研究の羅針盤】基礎医学編 上皮間葉転換ががんの浸潤転移に果たす役割 細胞工学. 2010.10; 別冊 (がん転移 臨床と研究の羅針盤): 166-169. ( 医中誌 )
有馬 好美, 佐谷 秀行: 神経線維腫形成の分子機構に対する新たな治療戦略の考案 日本レックリングハウゼン病学会雑誌. 2010.10;
有馬 好美, 神谷 敏夫, 佐谷 秀行: 【転移とは何か】基礎 上皮間葉転換と癌浸潤転移 細胞工学. 2009.06; 28 (7): 655-658. ( 医中誌 )
中田隆夫 : 東京医科歯科大学の教授就任にあたって 解剖学雑誌 vol.84;26-27,2009. 2009; 84 26-27.
有馬 好美, 佐谷 秀行: 【癌とゲノム】癌におけるゲノム不安定性 ゲノム医学. 2005.04;
中田隆夫: 細胞内膜動態に関わる細胞骨格蛋白質について 解剖学雑誌. 1998.04; 73 (2): 107-110.
Cheng, LH; Wang, YH; Xiang, L; Qi, JH: Heat Shock Cognate 70 kDa Protein Is the Target of Tetradecyl 2,3-Dihydroxybenzoate for Neuritogenic Effect in PC12 Cells BIOMEDICINES. 2021.10; 9 (10): 1483. ( PubMed , DOI )
Cheng, LH; Osada, H; Xing, TY; Yoshida, M; Xiang, L; Qi, JH: The Insulin Receptor: A Potential Target of Amarogentin Isolated from Gentiana rigescens Franch That Induces Neurogenesis in PC12 Cells BIOMEDICINES. 2021.05; 9 (5): ( PubMed , DOI )
Pan, YJ; Liu, YN; Fujii, R; Farooq, U; Cheng, LH; Matsuura, A; Qi, JH; Xiang, L: Ehretiquinone from Onosma bracteatum Wall Exhibits Antiaging Effect on Yeasts and Mammals through Antioxidative Stress and Autophagy Induction OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2021.01; 2021 1-15. ( PubMed , DOI )
Disasa, D; Cheng, LH; Manzoor, M; Liu, Q; Wang, Y; Xiang, L; Qi, JH: Amarogentin from Gentiana rigescens Franch Exhibits Antiaging and Neuroprotective Effects through Antioxidative Stress OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2020.08; 2020 1-15. ( PubMed , DOI )
Liu, Q; Cheng, LH; Matsuura, A; Xiang, L; Qi, JH: Gentiopicroside, a Secoiridoid Glycoside from Gentiana rigescens Franch, Extends the Lifespan of Yeast via Inducing Mitophagy and Antioxidative Stress OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2020.08; 2020 1-12. ( PubMed , DOI )
豊島学, 蒋緒光, 小川覚之, 大西哲生, 吉原壯悟, SHABEESH Balan, 廣川信隆, 吉川武男: カルボニルストレス性統合失調症の発症脆弱性に関わるCRMP2の機能異常 統合失調症研究. 2020; 10 (1):