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Kanako Noritake, Jun Tsuruta, Koji Mizutani, Keiko Kondo, Hitomi Suzuki, Naoko Adachi, Naoko Seki, Ridan Cao, Risako Mikami, Sayaka Katagiri, Yuji Kabasawa, Hiroshi Nitta: Educational effects of dental hygiene student intervention in dental student clinical practicum Journal of Dental Sciences. 2024.10; ( DOI )
Nose M, Nitta A, Zheng Y, Kizukuri R, Nagao Y, Nagai S, Aizawa M.: Bioceramics Enhance the Anti-Tumor Activity of Immune Cells in Adoptive Immunotherapy International Journal of Molecular Sciences. 2024.09; 25 (19): 10567. ( DOI )
Nagai T, Shiba T, Komatsu, Watanabe T, Nemoto T, Maekawa S, Kobayashi R, Matsumura S, Ohsugi Y, Katagiri S, Takeuchi Y, Iwata T: Optimal 16S rRNA gene amplicon sequencing analysis for oral microbiota to avoid the potential bias introduced by trimming length, primer, and database Microbiology Spectrum. 2024.08; e-pub
Liu A, Hayashi M, Ohsugi Y, Katagiri S, Akira S, Iwata T, Nakashima T: The IL-33/ST2 axis is protective against acute inflammation during the course of periodontitis Nature Communications. 2024.03; 15 (1): 2707.
Shiba T, Komatsu K, Takeuchi Y, Koyanagi T, Taniguchi Y, Takagi T, Maekawa S, Nagai T, Kobayashi R, Matsumura S, Katagiri S, Izumi Y, Aoki A, Iwata T: Novel flowchart guiding the non-surgical and surgical management of peri-implant complications: a narrative review Bioenginnering. 2024.01; 11 (2): 118.
Aoki A, Mizutani K, Taniguchi Y, Lin T, Ohsugi Y, Mikami R, Katagiri S, Meinzer W, Iwata T: Current status of Er:YAG laser in periodontal surgery. The Japanese dental science review. 2023.12; 60 1-14. ( PubMed , DOI )
Lin P, Liu A, Tsuchiya Y, Noritake K, Ohsugi Y, Toyoshima K, Tsukahara Y, Shiba T, Nitta H, Aoki A, Iwata T, Katagiri S: Association between periodontal disease and chronic obstructive pulmonary disease Japanese Dental Science Review. 2023.12; 59 389-402. ( PubMed , DOI )
Lin P, Niimi H, Hirota T, Ohsugi Y, Shimohira T, Toyoshima K, Katagiri S, Iwata T, Aoki A: Effects of low-level Er:YAG laser irradiation on proliferation and gene expression in primary gingival fibroblasts isolated from mouse maxilla Journal of biophotonics. 2023.11; 17 (2): e202300166. ( PubMed , DOI )
Hirasawa I, Odagiri H, Park G, Sanghavi R, Oshita T, Togi A, Yoshikawa K, Mizutani K, Takeuchi Y, Kobayashi H, Katagiri S, Iwata T, Aoki A: Anti-inflammatory effects of cold atmospheric plasma irradiation on the THP-1 human acute monocytic leukemia cell line. PloS one. 2023.10; 18 (10): e0292267. ( PubMed , DOI )
Toyoshima K, Ohsugi Y, Lin P, Komatsu K, Shiba T, Takeuchi Y, Hirota T, Shimohira T, Tsuchiya Y, Katagiri S, Iwata T, Aoki A: Blue LED irradiation without a photosensitizer alters oral microbiome composition of ligature-induced periodontitis in mice Photobiomodulation, Photomedicine, and Laser Surgery. 2023.10;
Daroonpan P, Ouchi R, Zhang C, Nagai S, Nishii N, Kashima Y, Tsushima F, Harada H, Hamagaki M, Ikeda T, Aida J, Kaomongkolgit R, Azuma M: Personal immune profiles: Diversity and prognostic value for oral tongue squamous cell carcinoma evaluated by comprehensive immune parameter analyses with multiplex immunofluorescence. Oral oncology. 2023.08; 143 106458. ( PubMed , DOI )
Katagiri S, Ohsugi Y, Shiba T, Yoshimi K, Nakagawa K, Nagasawa Y, Uchida A, Liu A, Lin P, Tsukahara Y, Iwata T, Tohara H: Homemade blenderized tube feeding improves gut microbiome communities in children with enteral nutrition Frontiers in Microbiology. 2023.08; 14 1215236.
Shiba T, Komatsu K, Watanabe T, Takeuchi Y, Nemoto T, Ohsugi Y, Katagiri S, Shimogishi M, Marukawa E, Iwata T: Peri-implantitis management by resective surgery combined with implantoplasty and Er:YAG laser irradiation, accompanied by free gingival graft: a case report. Therapeutic advances in chronic disease. 2023.06; 14 20406223231174816. ( PubMed , DOI )
Kataoka A, Shiba T, Katagiri S, Koyama S, Kito K, Ota T, Katayama T, Ohsugi Y, Nagai T, Kobayashi R, Komatsu K, Urata M, Imazuru T, Iwata T, Kozuma K: Novel and efficient method for diagnosing infective endocarditis using 16S ribosomal RNA gene amplicon sequence JACC Case Reports. 2023.04; 11 101793. ( PubMed , DOI )
Nashimoto Y, Hori T, Ostrovidov S, Katagiri S, Kaji H: Engineering oral microenvironments using microphysiological systems Sensors and Materials. 2023.04; 35 (4): 1293-1299.
Namangkalakul W, Nagai S, Jin C, Nakahama KI, Yoshimoto Y, Ueha S, Akiyoshi K, Matsushima K, Nakashima T, Takechi M, Iseki S: Augmented effect of fibroblast growth factor 18 in bone morphogenetic protein 2-induced calvarial bone healing by activation of CCL2/CCR2 axis on M2 macrophage polarization. Journal of tissue engineering. 2023.01; 14 20417314231187960. ( PubMed , DOI )
Ohsugi Y, Hatasa M, Katagiri S, Hirota T, Shimohira T, Shiba T, Komatsu K, Tsuchiya Y, Fukuba S, Lin P, Toyoshima K, Maekawa S, Niimi H, Iwata T, Aoki A: High-frequency pulsed diode laser irradiation inhibits bone resorption in mice with ligature-induced periodontitis Journal of Clinical Periodontology. 2022.12; 49 (12): 1275-1288. ( PubMed , DOI )
Nagasawa Y, Katagiri S, Nakagawa K, Hirota T, Yoshimi K, Uchida A, Hatasa M, Komatsu K, Shiba T, Ohsugi Y, Uesaka N, Iwata T, Tohara H: Xanthan gum-based fluid thickener decreases postprandial blood glucose associated with increase of Glp1 and Glp1r expression in ileum and alteration of gut microbiome Journal of Functional Foods. 2022.11; e-pub
Park K, Li Q, Lynes MD, Yokomizo H, Maddaloni E, Shinjo T, St-Louis R, Li Q, Katagiri S, Fu J, Clermont A, Park H, Wu IH, Yu MG, Shah H, Tseng YH, King GL: Endothelial cells induced progenitors into brown fat to reduce atherosclerosis Circulation Research. 2022.07; 131 (2): 168-183. ( PubMed , DOI )
Shiba T, Katagiri S, Komatsu K, Nemoto T, Takeuchi Y, Chen B, Zhou YS, Iwata T: Treatment of peri-implantitis caused by malpositioning and an extra implant: a case report International Journal of Periodontics & Restorative Dentistry. 2022.01; 42 (1): e15-e20. ( PubMed , DOI )
Wongtim K, Ikeda E, Ohno T, Nagai S, Okuhara S, Kure K, Azuma M: Overexpression of PD-L1 in gingival basal keratinocytes reduces periodontal inflammation in a ligature-induced periodontitis model. J Periodontol. 2022.01; 93 (1): 146-155. ( PubMed , DOI )
Yoshida S, Hatasa M, Ohsugi Y, Tsuchiya Y, Liu A, Niimi H, Morita K, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Okano T, Hirose A, Ibi R, Noritake K, Tomiga Y, Nitta H, Suzuki T, Takahashi H, Miyasaka N, Iwata T, Katagiri S: Porphyromonas gingivalis administration induces gestational obesity, alters gene expression in the liver and brown adipose tissue in pregnant mice, and causes underweight in fetuses Frontiers in Cellular and Infection Microbiology. 2022.01; 11 745117. ( PubMed , DOI )
Nemoto T, Shiba T, Komatsu K, Watanabe T, Shimogishi M, Shibasaki M, Koyanagi T, Nagai T, Katagiri S, Takeuchi Y, Iwata T: Discrimination of bacterial community structures among healthy, gingivitis, and periodontitis statuses through integrated metatranscriptomic and network analyses. mSystems. 2021.10; 6 (6): e0088621. ( PubMed , DOI )
Shiba T, Komatsu K, Sudo T, Sawafuji R, Saso A, Ueda S, Watanabe T, Nemoto T, Kano C, Nagai T, Ohsugi Y, Katagiri S, Takeuchi Y, Kobayashi H, Iwata T: Comparison of periodontal bacteria of Edo and modern periods using novel diagnostic approach for periodontitis with micro-CT. Frontiers in cellular and infection microbiology. 2021.09; 11 723821. ( PubMed , DOI )
Lin P, Niimi H, Ohsugi Y, Tsuchiya Y, Shimohira T, Komatsu K, Liu A, Shiba T, Aoki A, Iwata T, Katagiri S: Application of Ligature-Induced Periodontitis in Mice to Explore the Molecular Mechanism of Periodontal Disease International Journal of Molecular Sciences. 2021.08; 22 (16): 8900. ( PubMed , DOI )
Kataoka A, Katagiri S, Kawashima H, Nagura F, Nara Y, Hioki H, Nakashima M, Sasaki N, Hatasa M, Maekawa S, Ohsugi Y, Shiba T, Watanabe Y, Shimokawa T, Iwata T, Kozuma K: Association between Periodontal Bacteria and Degenerative Aortic Stenosis: A Pilot Study Journal of Periodontal and Implant Science. 2021.08; 51 (4): 226-238.
Shimohira T, Niimi H, Ohsugi Y, Tsuchiya Y, Morita K, Yoshida S, Hatasa M, Shiba T, Kadokura H, Yokose S, Katagiri S, Iwata T, Aoki A: Low-level erbium-doped yttrium aluminum garnet laser irradiation induced alteration of gene expression in osteogenic cells from rat calvariae Photobiomodulation, Photobiomedicine, and Laser Surgery. 2021.08; 39 (8): 566-577. ( DOI )
Shiba T, Watanabe T, Komatsu K, Koyanagi T, Nemoto T, Ohsugi Y, Michi Y, Katagiri S, Takeuchi Y, Ishihara K, Iwata T: Non-surgical treatment for periodontitis and peri-implantitis: longitudinal clinical and bacteriological findings-A case report with a 7-year follow-up evaluation. SAGE open medical case reports. 2021.07; 9 2050313X211029154. ( PubMed , DOI )
Aoki A, Mizutani K, Mikami R, Taniguchi Y, Ohsugi Y, M Walter, Izumi Y, Iwata T.: Residual periodontal pocket treatment with Er:YAG laser-assisted comprehensive periodontal pocket therapy: a retrospective study CLINICAL ORAL INVESTIGATIONS. 2021.07; 26 (1): 761-771. ( PubMed , DOI )
Ao X, Yang Y, Okiji T, Azuma M, Nagai S: Polymorphonuclear Myeloid-derived cells that contribute to the immune paralysis are generated in the early phase of sepsis via PD-1/PD-L1 pathway. Infection and Immunity. 2021.05; 89 (6): e00771-20. ( PubMed , DOI )
Hatasa M, Yoshida S, Takahashi H, Tanaka K, Kubotsu Y, Ohsugi Y, Katagiri T, Iwata T, Katagiri S: Relationship between NAFLD and Periodontal Disease from the View of Clinical and Basic Research, and Immunological Response International Journal of Molecular Sciences. 2021.04; 22 (7): 3728.
Ishihama H, Ishii K, Nagai S, Kakinuma H, Sasaki A, Yoshioka K, Kuramoto T, Shiono Y, Funao H, Isogai N, Tsuji T, Okada Y, Koyasu S, Toyama Y, Nakamura M, Aizawa M, Matsumoto M: An antibacterial coated polymer prevents biofilm formation and implant-associated infection. Scientific Reports. 2021.02; 11 (1): 3602. ( PubMed , DOI )
Shimohira T, Katagiri S, Ohsugi Y, Hirota T, Hatasa M, Mizutani K, Watanabe K, Niimi H, Iwata T, Aoki A: Comprehensive and Sequential Gene Expression Analysis of Bone Healing Process Following Er:YAG Laser Ablation Photobiomodulation, Photobiomedicine, and Laser Surgery. 2021.02; 39 (2): 100-112. ( PubMed , DOI )
Harada Y, Sunaga M, Takeuchi Y, Mizutani K, Katagiri S, Ikeda Y, Aoki A, Iwata T, Kinoshita A: Standardization of examiners using a dental model for pocket probe training: Adequacy of evaluation with model and standard accuracy rate of skilled examiners Journal of medical and dental sciences. 2021.02; 68 49-54.
Watanabe K, Katagiri S, Takahashi H, Sasaki N, Maekawa S, Komazaki R, Hatasa M, Kitajima Y, Maruyama Y, Shiba T, Komatsu K, Ohsugi Y, Tanaka K, Matsuzawa A, Hirota T, Tohara H, Eguchi Y, Anzai K, Hattori A, Iwata T: Porphyromonas gingivalis impairs glucose uptake in skeletal muscle associated with altering gut microbiota FASEB JOURNAL. 2021.02; 35 (2): e21171. ( PubMed , DOI )
Hatasa M, Ohsugi Y, Katagiri S, Yoshida S, Niimi H, Morita K, Tsuchiya Y, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Tohara H, Takahashi H, Nitta H, Iwata T: Endotoxemia by Porphyromonas gingivalis alters endocrine functions in brown adipose tissue Frontiers in Cellular and Infection Microbiology. 2021.01; 19 (10): 580577.
Nagata M, Toyonaga K, Ishikawa E, Haji S, Okahashi N, Takahashi M, Izumi Y, Imamura A, Takato K, Ishida H, Nagai S, Illarionov P, Stocker BL, Timmer MSM, Smith DGM, Williams SJ, Bamba T, Miyamoto T, Arita M, Appelmelk BJ, Yamasaki S: Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors. Journal of Experimental Medicine. 2021.01; 218 (1): e20200815. ( PubMed , DOI )
Komatsu K, Shiba T, Takeuchi Y, Watanabe T, Koyanagi T, Nemoto T, Shimogishi M, Shibasaki M, Katagiri S, Kasugai S, Iwata T: Discriminating Microbial Community Structure Between Peri-Implantitis and Periodontitis With Integrated Metagenomic, Metatranscriptomic, and Network Analysis Frontiers in Cellular and Infection Microbiology, Tokyo Medical and Dental University. 2020.12; 10 596490. ( DOI )
Ohsugi Y, Niimi H, Shimohira T, Hatasa M, Katagiri S, Aoki A, Iwata T: In vitro cytological responses against laser photobiomodulation for periodontal regeneration International Journal of Molecular Sciences. 2020.11; 21 (23): 9002.
Inagaki K, Kikuchi T, Noguchi T, Mitani A, Naruse K, Matsubara T, Kawanami M, Negishi J, Furuichi Y, Nemoto E, Yamada S, Yoshie H, Tabeta K, Tomita S, Saito A, Katagiri S, Izumi Y, Nitta H, Iwata T, Numabe Y, Yamamoto M, Yoshinari N, Fujita T, Kurihara H, Nishimura F, Nagata T, Yumoto H, Naito T, Noguchi K, Ito K, Murakami S, Nishimura R, Tajima N: A large-scale observational study to investigate the current status of diabetic complications and their prevention in Japan (JDCP study 6): baseline dental and oral findings Diabetology International. 2020.10; e-pub
Ohsugi Y, Katagiri S, Hirota T, Niimi H, Hatasa M, Watanabe K, Shimohira T, Mizutani K, Kitazawa M, Matsuzawa A, Kadokura H, Yokose S, Iwata T, Aoki A: Laser irradiation decreases sclerostin expression in bone and osteogenic cells. The FASEB Journal. 2020.08; 34 (9): 12877-12893. ( PubMed , DOI )
Niimi H, Ohsugi Y, Katagiri S, Watanabe K, Hatasa M, Shimohira T, Tsuchiya Y, Maekawa S, Hirota T, Kadokura H, Yokose S, Iwata T, Aoki A: Effects of low-level Er:YAG laser irradiation on proliferation and calcification of primary osteoblast-like cells Isolated from rat calvaria Frontiers in cell and developmental biology, Tokyo Medical and Dental University. 2020.06; 6 459.
Suzuki S, Aoki A, Katagiri S, Maekawa S, Ejiri K, Kong S, Nagata M, Yamaguchi Y, Ohshima M, Izumi Y: Detection of hepatocyte growth factor in oral rinses using water for possible periodontal diagnosis. Journal of Oral Science. 2020.06; 62 (3): 250-255. ( PubMed , DOI )
Kashima Y, Nishii N, Tachinami H, Furusawa E, Nagai S, Harada H, Azuma M: Orthotopic tongue squamous cell carcinoma (SCC) model exhibiting a different tumor-infiltrating T-cell status with margin-restricted CD8#U + #URT cells and regulatory T cell-dominance, compared to skin SCC. Biochem Biophys Res Commun.. 2020.05; 526 (1): 218-224. ( PubMed , DOI )
Ye C, Katagiri S, Miyasaka N, Kobayashi H, Khemwong T, Nagasawa T, Izumi Y: The periodontopathic bacteria in placenta, saliva and subgingival plaque of threatened preterm labor and preterm low birth weight cases: a longitudinal study in Japanese pregnant women Clinical Oral Investigations. 2020.04; 24 (12): 4261-4270. ( PubMed , DOI )
Ogawa M, Katagiri S, Koyanagi T, Maekawa S, Shiba T, Ohsugi Y, Takeuchi Y, Ikawa T, Takeuchi S, Sekiuchi T, Arai Y, Kazama R, Wakabayashi N, Izumi Y, Iwata T: Accuracy of cone beam computed tomography in evaluation of palatal mucosa thickness Journal of Clinical Periodontology, Tokyo Medical and Dental University. 2020.04; 47 (4): 479-488. ( PubMed , DOI )
Tanaka K, Takahashi H, Katagiri S, Sasaki K, Ohsugi Y, Watanabe K, Rasadul IMD, Mine K, Nagafuchi S, Iwata T, Eguchi Y, Anzai K: Combined effect of canagliflozin and exercise training on high-fat diet-fed mice. American journal of physiology. Endocrinology and metabolism. 2020.04; 318 (4): E492-E503. ( PubMed , DOI )
Ye C, Kobayashi H, Katagiri S, Miyasaka N, Takeuchi Y, Kuraji R, Izumi Y: The relationship between the anti-#IPorphyromonas gingivalis#IR immunoglobulin G subclass antibody and small for gestational age delivery: a longitudinal study in pregnant Japanese women. International dental journal. 2020.03; 70 (4): 296-302. ( PubMed , DOI )
Yue Yang, Shigenori Nagai, Siwen Kang, Yulong Xia, Yohei Kawano, Kensuke Miyake, Hajime Karasuyama, Miyuki Azuma: Tolerogenic properties of CD206+ macrophages appeared in the sublingual mucosa after repeated antigen-painting. Int. Immunol.. 2020.03; ( PubMed , DOI )
Kasai S, Onizuka S, Katagiri S, Nakamura T, Hanatani T, Kudo T, Sugata Y, Ishimatsu M, Usui M, Nakashima K: Associations of cytokine levels in gingival crevicular fluid of mobile teeth with clinical improvement after initial periodontal treatment Journal of oral science. 2020.03; 62 (2): 189-196. ( PubMed , DOI )
Fujii M, Kawashima N, Tazawa K, Hashimoto K, Nara K, Noda S, Kuramoto M, Orikasa S, Nagai S, Okiji T : HIF1α inhibits LPS-mediated induction of IL-6 synthesis via SOCS3-dependent CEBPβ suppression in human dental pulp cells Biochemical and Biophysical Research Communications . 2020.02; 522 (2): 308-314. ( PubMed , DOI )
Nakagawa D, Nakamura M, Nagai S, Aizawa M: Fabrications of boron-containing apatite ceramics via ultrasonic spray-pyrolysis route and their responses to immunocytes J Mater Sci Mater Med.. 2020.01; 31 (2): 20. ( PubMed , DOI )
Fujii M, Kawashima N, Tazawa K, Hashimoto K, Nara K, Noda S, Nagai S, Okiji T.: Hypoxia-inducible factor 1α promotes interleukin 1β and tumour necrosis factor α expression in lipopolysaccharide-stimulated human dental pulp cells. International Endodontic Journal. 2020.01; ( DOI )
Hatasa M, Ohsugi Y, Katagiri S, Yoshida S, Niimi H, Morita K, Tsuchiya Y, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Tohara H, Takahashi H, Nitta H, Iwata T.: Endotoxemia by Porphyromonas gingivalis alters endocrine functions in brown adipose tissue Frontiers in Cellular and Infection Microbiology. 2020; 10 580577. ( PubMed , DOI )
Katagiri S, Shiba T, Tohara H, Yamaguchi K, Hara K, Nakagawa K, Komatsu K, Watanabe K, Ohsugi Y, Maekawa S, Iwata T: Re-initiation of Oral Food Intake Following Enteral Nutrition Alters Oral and Gut Microbiota Communities FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2019.12; 9 434. ( PubMed , DOI )
Nagai S, Azuma M: The CD28-B7 family of co-signaling molecules. Adv Exp Med Biol.. 2019.11; 1189 25-51. ( PubMed , DOI )
Furusawa E, Ohno T, Nagai S, Noda T, Komiyama T, Kobayashi K, Hamamoto H, Miyashin M, Yokozeki H, Azuma M: Silencing of PD-L2/B7-DC by topical application of small interfering RNA inhibits elicitation of contact hypersensitivity. J Invest Dermatol. 2019.10; 139 (10): 2164-2173.e1. ( PubMed , DOI )
Maekawa S, Onizuka S, Katagiri S, Hatasa M, Ohsugi Y, Sasaki N, Watanabe K, Ohtsu A, Komazaki R, Ogura K, Miyoshi-Akiyama T, Iwata T, Nitta H, Izumi Y: RNA sequencing for ligature induced periodontitis in mice revealed important role of S100A8 and S100A9 for periodontal destruction Scientific Reports. 2019.10; 9 (1): 14663. ( PubMed , DOI )
Xia Y, Ohno T, Nishii N, Bhingare A, Tachinami H, Kashima Y, Nagai S, Saito H, Nakae S, Azuma M: Endogenous IL-33 exerts CD8+ T cell antitumor responses overcoming pro-tumor effects by regulatory T cells in a colon carcinoma model Biochemical and Biophysical Research Communications. 2019.08; 518 (2): 331-336. ( PubMed , DOI )
Watanabe K, Ohsugi Y, Maekawa S, Sasaki N, Shiba T, Katagiri S, Arakawa S: Ozone Ultrafine Bubble Water improves wound healing via modification of inflammation Journal of the Stomatological Society. 2019.07; 86 (2): 25-34.
渡辺数基, 大杉勇人, 前川祥吾, 佐々木直樹, 芝多佳彦, 片桐さやか, 荒川真一: 創傷治癒モデルマウスにおける炎症因子を介したオゾンウルトラファインバブル水の効果(Ozone Ultrafine Bubble Water Improves Wound Healing via Modification of Inflammation) 口腔病学会雑誌. 2019.07; 86 (2): 25-35. ( ichushi )
Katagiri T, Yamazaki S, Fukui Y, Aoki K, Yagita H, Nishina T, Mikami T, Katagiri S, Shiraishi A, Kimura S, Tateda K, Sumimoto H, Endo S, Kameda H, Nakano H: JunB plays a crucial role in development of regulatory T cells by promoting IL-2 signaling. Mucosal Immunol. 2019.07; ( PubMed , DOI )
Yokomizo H, Maeda Y, Park K, Clermont AC, Hernandez SL, Fickweiler W, Li Q, Wang CH, Paniagua SM, Simao F, Ishikado A, Sun B, Wu IH, Katagiri S, Pober DM, Tinsley LJ, Avery RL, Feener EP, Kern TS, Keenan HA, Aiello LP, Sun JK, King GL: Retinol binding protein 3 is increased in the retina of patients with diabetes resistant to diabetic retinopathy. Sci Transl Med. 2019.07; 11 (499): ( PubMed , DOI )
Aung N, Aoki A, Takeuchi Y, Hiratsuka K, Katagiri S, Kong S, Shujaa Addin A, Meinzer W, Sumi Y, Izumi Y: The effects of ultraviolet light-emitting diodes with different wavelengths on periodontopathic acteria #IIn Vitro#IR. Photobiomodulation, photomedicine, and laser surgery. 2019.05; 37 (5): 288-297. ( PubMed , DOI )
Tanaka K, Takahashi H, Eguchi Y, Katagiri S, Ohsugi Y, Watanabe K, Iwata T, Anzai K: 肥満者と糖尿病患者の骨格筋に及ぼすcanagliflozinと運動の効果(The effects of canagliflozin and exercise training on skeletal muscle in obesity and diabetes) 糖尿病. 2019.04; 62 (Suppl.1): S-370. ( ichushi )
Tachinami H, Nishii N, Xia Y, Kashima Y, Ohno T, Nagai S, Li L, Lau W, Tomihara K, Noguchi M, Azuma M: Differences of tumor-recruiting myeloid cells in murine squamous cell carcinoma influence the efficacy of immunotherapy combined with a TLR7 agonist and PD-L1 blockade. Oral Oncology. 2019.04; 91 21-28. ( PubMed , DOI )
Kagami S, Kizukuri R, Nagai S, *Aizawa M.: Responses of Immune Cells to Hydroxyapatite Ceramics Loaded with Immunostimulators. J Soc Inorg Mater Jpn.. 2019.03; 26 (399): 74-81.
Ohsugi Y, Aoki A, Mizutani K, Katagiri S, Komaki M, Noda M, Takagi T, Kakizaki S, Meinzer W, Izumi Y: Evaluation of bone healing following Er:YAG laser ablation in rat calvaria compared with bur drilling. Journal of Biophotonics. 2019.03; 12 (3): e201800245. ( PubMed , DOI )
Ohtsu A, Takeuchi Y, Katagiri S, Suda W, Maekawa S, Shiba T, Komazaki R, Udagawa S, Sasaki N, Hattori M, Izumi Y: Influence of #IPorphyromonas gingivalis#IR in gut microbiota of streptozotocin-induced diabetic mice. Oral diseases. 2019.01; 25 (3): 868-880. ( PubMed , DOI )
Maekawa Shogo, Suzuki Shinta, Aoki Akira, Katagiri Sayaka, Ikeda Yuichi, Ejiri Kenichiro, Kong Sophannary, Nagata Mizuki, Yamaguchi Yoko, Ohshima Mitsuhiro, Izumi Yuichi: 肝細胞増殖因子を用いた歯周炎の新規スクリーニングシステム(A new screening system for periodontitis using Hepatocyte growth factor) 日本歯周病学会会誌. 2018.12; 60 (4): 240. ( ichushi )
Sasaki N, Katagiri S, Komazaki R, Watanabe K, Maekawa S, Shiba T, Udagawa S, Takeuchi Y, Ohtsu A, Kohda T, Tohara H, Miyasaka N, Hirota T, Tamari M, Izumi Y: Endotoxemia by #IPorphyromonas gingivalis#IR injection aggravates non-alcoholic fatty liver disease, disrupts glucose/lipid metabolism, and alters gut microbiota in mice. Frontiers in Microbiology. 2018.10; 9 2470. ( PubMed , DOI )
Rina Komazaki, Sayaka Katagiri, Hirokazu Takahashi, Shogo Maekawa, Takahiko Shiba, Yasuo Takeuchi, Yoichiro Kitajima, Anri Ohtsu, Sayuri Udagawa, Naoki Sasaki, Kazuki Watanabe, Noriko Sato, Naoyuki Miyasaka, Yuichiro Eguchi, Keizo Anzai, Yuichi Izumi: Author Correction: Periodontal pathogenic bacteria, Aggregatibacter actinomycetemcomitans affect non-alcoholic fatty liver disease by altering gut microbiota and glucose metabolism. Sci Rep. 2018.03; 8 (1): 4620. ( PubMed , DOI )
Nishii N, Tachinami H, Kondo Y, Xia Y, Kashima Y, Ohno T, Nagai S, Li L, Lau W, Harada H, Azuma M: Systemic administration of a TLR7 agonist attenuates regulatory T cells by dendritic cell modification and overcomes resistance to PD-L1 blockade therapy. Oncotarget. 2018.03; 9 (17): 13301-13312. ( PubMed , DOI )
Udagawa S, Katagiri S, Maekawa S, Takeuchi Y, Komazaki R, Ohtsu A, Sasaki N, Shiba T, Watanabe K, Ishihara K, Sato N, Miyasaka N, Izumi Y: Effect of #IPorphyromonas gingivalis#IR infection in the placenta and umbilical cord in pregnant mice with low birth weight. Acta Odontologica Scandinavica. 2018.01; 1-9. ( PubMed , DOI )
Nadya NA, Tezuka H, Ohteki T, Matsuda S, Azuma M, Nagai S: PI3K-Akt pathway enhances the differentiation of interleukin-27-induced type 1 regulatory T cells. Immunology. 2017.11; 152 (3): 507-516. ( PubMed , DOI )
Rina Komazaki, Sayaka Katagiri, Hirokazu Takahashi, Shogo Maekawa, Takahiko Shiba, Yasuo Takeuchi, Yoichiro Kitajima, Anri Ohtsu, Sayuri Udagawa, Naoki Sasaki, Kazuki Watanabe, Noriko Sato, Naoyuki Miyasaka, Yuichiro Eguchi, Keizo Anzai, Yuichi Izumi: Periodontal pathogenic bacteria, Aggregatibacter actinomycetemcomitans affect non-alcoholic fatty liver disease by altering gut microbiota and glucose metabolism Scientific Reports. 2017.10;
Kong S, Aoki A, Iwasaki K, Mizutani K, Katagiri S, Suda T, Ichinose S, Ogita M, Pavlic V, Izumi Y: Biological effects of Er:YAG laser irradiation on the proliferation of primary human gingival fibroblasts. J Biophotonics. 2017.10; epub ( PubMed , DOI )
Nitta Hiroshi, Katagiri Sayaka, Nagasawa Toshiyuki, Izumi Yuichi, Ishikawa Isao, Izumiyama Hajime, Uchimura Isao, Kanazawa Masao, Chiba Hiroshige, Matsuo Akira, Utsunomiya Kazunori, Tanabe Haruyasu, Takei Izumi, Asanami Soichiro, Kajio Hiroshi, Ono Toaki, Hayashi Yoichi, Ueki Kiichi, Tsuji Masatomi, Kurachi Yoichi, Yamanouchi Toshikazu, Ichinokawa Yoshimi, Inokuchi Toshiki, Fukui Akiko, Miyazaki Shigeru, Miyauchi Takashi, Kawahara Reiko, Ogiuchi Hideki, Yoshioka Narihito, Negishi Jun, Mori Masatomo, Mogi Kenji, Saito Yasushi, Tanzawa Hideki, Nishikawa Tetsuo, Takada Norihiko, Nanjo Kishio, Morita Nobuo, Nakamura Naoto, Kanamura Narisato, Makino Hirofumi, Nishimura Fusanori, Kobayashi Kunihisa, Higuchi Yoshinori, Sakata Toshiie, Yanagisawa Shigetaka, Tei Chuwa, Ando Yuichi, Hanada Nobuhiro, Inoue Shuji: 2型糖尿病患者における細小血管合併症数は歯周炎重症度のリスクの上昇と関連する 多施設共同病院ベース横断研究の結果(The number of microvascular complications is associated with an increased risk for severity of periodontitis in type 2 diabetes patients: Results of a multicenter hospital-based cross-sectional study) Journal of Diabetes Investigation. 2017.09; 8 (5): 677-686. ( ichushi )
Hua N, Takahashi H, Yee GM, Kitajima Y, Katagiri S, Kojima M, Anzai K, Eguchi Y, Hamilton JA: Influence of muscle fiber type composition on early fat accumulation under high-fat diet challenge. PLoS ONE. 2017.08; 12 (8): e0182430. ( PubMed , DOI )
Saito Akira, Horie Masafumi, Ejiri Kenichiro, Aoki Akira, Katagiri Sayaka, Maekawa Shogo, Suzuki Shinta, Kong Sophannary, Yamauchi Tsuneto, Yamaguchi Yoko, Izumi Yuichi, Ohshima Mitsuhiro: MicroRNA profiling in gingival crevicular fluid of periodontitis-a pilot study FEBS OPEN BIO. 2017.07; 7 (7): 981-994. ( PubMed , DOI )
Saito A, Horie M, Ejiri K, Aoki A, Katagiri S, Maekawa S, Suzuki S, Kong S, Yamauchi T, Yamaguchi Y, Izumi Y, Ohshima M: MicroRNA profiling in gingival crevicular fluid of periodontitis—a pilot study FEBS Openbio. 2017.06; e-pub
Nitta H, Katagiri S, Nagasawa T, Izumi Y, Ishikawa I, Izumiyama H et al.: The number of microvascular complications is associated with an increased risk for severity of periodontitis in type 2 diabetes patients: Results of a multicenter hospital-based cross-sectional study. J Diabetes Investig. 2017.05; 8 677-686. ( PubMed , DOI )
Maekawa S, Katagiri S, Takeuchi Y, Komazaki R, Ohtsu A, Udagawa S, Izumi Y: Bone metabolic microarray analysis of ligature-induced periodontitis in streptozotocin-induced diabetic mice. J. Periodont. Res.. 2017.04; 52 (2): 233-245. ( PubMed , DOI )
Kong Sophannary, Aoki Akira, Iwasaki Kengo, Mizutani Koji, Suda Tomonari, Katagiri Sayaka, Ogita Mayumi, Ando Yoshinori, Izumi Yuichi: ヒト歯肉線維芽細胞の増殖に及ぼすEr:YAGレーザー照射の効果(Effects of Er:YAG laser irradiation on proliferation of human gingival fibroblasts) 日本歯周病学会会誌. 2017.04; 59 (春季特別): 118. ( ichushi )
Maekawa Shogo, Katagiri Sayaka, Takeuchi Yasuo, Komazaki Rina, Ohtsu Anri, Udagawa Sayuri, Izumi Yuichi: ストレプトゾトシン誘発性糖尿病マウスにおける結紮誘発性歯周炎の骨代謝マイクロアレイ分析(Bone Metabolic Microarray Analysis of Ligature-Induced-Periodontitis in Streptozotocin-Induced Diabetic Mice) 日本歯周病学会会誌. 2016.11; 58 (3): 168. ( ichushi )
Yutaka Kurebayashi, Yukiko Baba, Akiko Minowa, Niken Adiba Nadya, Miyuki Azuma, Akihiko Yoshimura, Shigeo Koyasu, Shigenori Nagai: TGF-β-induced phosphorylation of Akt and Foxo transcription factors negatively regulates induced regulatory T cell differentiation. Biochem. Biophys. Res. Commun.. 2016.11; 480 (1): 114-119. ( PubMed , DOI )
Katagiri S, Park K, Maeda Y, Rao TN, Khamaisi M, Li Q, Yokomizo H, Mima A, Lancerotto L, Wagers A, Orgill DP, King GL: Overexpressing IRS1 in Endothelial Cells Enhances Angioblast Differentiation and Wound Healing in Diabetes and Insulin Resistance. Diabetes. 2016.09; 65 (9): 2760-2771. ( PubMed , DOI )
Yuta Shiono, Ken Ishii, Shigenori Nagai, Hiroaki Kakinuma, Aya Sasaki, Haruki Funao, Tetsuya Kuramoto, Kenji Yoshioka, Hiroko Ishihama, Norihiro Isogai, Kenichiro Takeshima, Takashi Tsuji, Yasunori Okada, Shigeo Koyasu, Masaya Nakamura, Yoshiaki Toyama, Mamoru Aizawa, Morio Matsumoto: Delayed Propionibacterium acnes surgical site infections occur only in the presence of an implant. Sci Rep. 2016.09; 6 32758. ( PubMed , DOI )
Yusuke Yamazumi, Oh Sasaki, Mitsuru Imamura, Takeaki Oda, Yoko Ohno, Yumi Shiozaki-Sato, Shigenori Nagai, Saki Suyama, Yuki Kamoshida, Kosuke Funato, Teruhito Yasui, Hitoshi Kikutani, Kazuhiko Yamamoto, Makoto Dohi, Shigeo Koyasu, Tetsu Akiyama: The RNA Binding Protein Mex-3B Is Required for IL-33 Induction in the Development of Allergic Airway Inflammation. Cell Rep. 2016.08; 16 (9): 2456-2471. ( PubMed , DOI )
Park K, Mima A, Li Q, Rask-Madsen C, He P, Mizutani K, Katagiri S, Maeda Y, Wu IH, Khamaisi M, Preil SR, Maddaloni E, Sørensen D, Rasmussen LM, Huang PL, King GL: Insulin decreases atherosclerosis by inducing endothelin receptor B expression. JCI Insight. 2016.05; 1 (6): e86574. ( PubMed , DOI )
Ye Changchang, Kobayashi Hiroaki, Katagiri Sayaka, Komazaki Rina, Yuichi Izumi: 緊急早産と早産の症例におけるPorphyromonas gingivalisに対する免疫グロブリンGサブクラス抗体の役割(The role of immunoglobulin G subclass antibodies against Porphyromonas. gingivalis in threatened preterm labor and preterm birth cases) 日本歯周病学会会誌. 2016.04; 58 (春季特別): 113. ( ichushi )
Khamaisi M, Katagiri S, Keenan H, Park K, Maeda Y, Li Q, Qi W, Thomou T, Eschuk D, Tellechea A, Veves A, Huang C, Orgill DP, Wagers A, King GL: PKCδ inhibition normalizes the wound-healing capacity of diabetic human fibroblasts. J. Clin. Invest.. 2016.03; 126 (3): 837-853. ( PubMed , DOI )
Haruki Funao, Shigenori Nagai, Aya Sasaki, Tomoyuki Hoshikawa, Takashi Tsuji, Yasunori Okada, Shigeo Koyasu, Yoshiaki Toyama, Masaya Nakamura, Mamoru Aizawa, Morio Matsumoto, Ken Ishii: A novel hydroxyapatite film coated with ionic silver via inositol hexaphosphate chelation prevents implant-associated infection. Sci Rep. 2016.03; 6 23238. ( PubMed , DOI )
Asahi K, Imazeki N, Takahashi T, Takeuchi M, Kimura N, Sasaki E, Uchino H, Murasugi K, Hayakawa A, Katagiri S, Ishizuka N, Suzuki Y, Sekiya K, Takahashi M, Sato E, Kawakubo K, Uehara Y, Ikemoto S, Inoue S: High prevalence of general and abdominal obesity and relationship of obesity with diabetes mellitus in patients with psychiatric disorders Journal of Diabetes and Obesity. 2014.12; 1 (2): 1-6. ( DOI )
Kenji Yoshioka, Ken Ishii, Tetsuya Kuramoto, Shigenori Nagai, Haruki Funao, Hiroko Ishihama, Yuta Shiono, Aya Sasaki, Mamoru Aizawa, Yasunori Okada, Shigeo Koyasu, Yoshiaki Toyama, Morio Matsumoto: A novel mouse model of soft-tissue infection using bioluminescence imaging allows noninvasive, real-time monitoring of bacterial growth. PLoS ONE. 2014.09; 9 (9): e106367. ( PubMed , DOI )
K Mizutani, K Park, A Mima, S Katagiri, G L King: Obesity-associated Gingival Vascular Inflammation and Insulin Resistance. J. Dent. Res.. 2014.04; 93 (6): 596-601. ( PubMed , DOI )
Okamoto T, Ishikawa I, Kumasaka A, Morita S, Katagiri S, Okano T, Ando T: Blue-violet light-emitting diode irradiation in combination with hemostatic gelatin sponge (Spongel) application ameliorates immediate socket bleeding in patients taking warfarin. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014.02; 117 (2): 170-177. ( PubMed , DOI )
Muhammad Baghdadi, Akihiro Yoneda, Tsunaki Yamashina, Hiroko Nagao, Yoshihiro Komohara, Shigenori Nagai, Hisaya Akiba, Marc Foretz, Hironori Yoshiyama, Ichiro Kinoshita, Hirotoshi Dosaka-Akita, Motohiro Takeya, Benoit Viollet, Hideo Yagita, Masahisa Jinushi: TIM-4 glycoprotein-mediated degradation of dying tumor cells by autophagy leads to reduced antigen presentation and increased immune tolerance. Immunity. 2013.12; 39 (6): 1070-1081. ( PubMed , DOI )
Ryuichi Murakami, Kaori Denda-Nagai, Shin-ichi Hashimoto, Shigenori Nagai, Masahira Hattori, Tatsuro Irimura: A unique dermal dendritic cell subset that skews the immune response toward Th2. PLoS ONE. 2013.09; 8 (9): e73270. ( PubMed , DOI )
Changchang Ye, Sayaka Katagiri, Naoyuki Miyasaka, Pariksha Bharti, Hiroaki Kobayashi, Yasuo Takeuchi, Yoshihito Momohara, Masaki Sekiguchi, Satoko Takamine, Toshiyuki Nagasawa, Yuichi Izumi: The anti-phospholipid antibody-dependent and independent effects of periodontopathic bacteria on threatened preterm labor and preterm birth. Arch. Gynecol. Obstet.. 2013.07; 288 (1): 65-72. ( PubMed , DOI )
Hideyuki Yoshida, Hitoshi Kotani, Taisuke Kondo, Ito Tani, Xuetao Wei, Sanae Tsuruta, Akihiro Kimura, Mayako Asakawa, Minako Ito, Shigenori Nagai, Akihiko Yoshimura: CDK inhibitors suppress Th17 and promote iTreg differentiation, and ameliorate experimental autoimmune encephalomyelitis in mice. Biochem. Biophys. Res. Commun.. 2013.06; 435 (3): 378-384. ( PubMed , DOI )
Katagiri S, Nitta H, Nagasawa T, Izumi Y, Kanazawa M, Matsuo A, Chiba H, Fukui M, Nakamura N, Oseko F, Kanamura N, Inagaki K, Noguchi T, Naruse K, Matsubara T, Miyazaki S, Miyauchi T, Ando Y, Hanada N, Inoue S: Effect of glycemic control on periodontitis in type 2 diabetic patients with periodontal disease. J Diabetes Investig. 2013.05; ( PubMed , DOI )
Yutaka Kurebayashi, Shigenori Nagai, Ai Ikejiri, Shigeo Koyasu: Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells. Genes Cells. 2013.04; 18 (4): 247-265. ( PubMed , DOI )
Shigenori Nagai, Yutaka Kurebayashi, Shigeo Koyasu: Role of PI3K/Akt and mTOR complexes in Th17 cell differentiation. Ann. N. Y. Acad. Sci.. 2013.03; 1280 30-34. ( PubMed , DOI )
Bharti P, Katagiri S, Nitta H, Nagasawa T, Kobayashi H, Takeuchi Y, Izumiyama H, Uchimura I, Inoue S, Izumi Y: Periodontal treatment with topical antibiotics improves glycemic control in association with elevated serum adiponectin in patients with type 2 diabetes mellitus. Obes Res Clin Pract. 2013.03; 7 (2): e129-e138. ( PubMed , DOI )
Almehdi A, Aoki A, Ichinose S, Taniguchi Y, Sasaki KM, Ejiri K, Sawabe M, Chui C, Katagiri S, Izumi Y: Histological and SEM analysis of root cementum following irradiation with Er:YAG and CO2 lasers. Lasers Med Sci. 2013.01; 28 (1): 203-213. ( PubMed , DOI )
Katagiri S, Nagasawa T, Kobayashi H, Takamatsu H, Bharti P, Izumiyama H, Uchimura I, Tagami T, Suzuki T, Nanbara H, Taniguchi Y, Hayakumo S, Koyanagi T, Himeno-Ando A, Goto M, Kajio H, Takahashi Y, Izumi Y, Noda M: Improvement of glycemic control after periodontal treatment by resolving gingival inflammation in type 2 diabetic patients with periodontal disease. 2012.08; ( PubMed , DOI )
Daisuke Sugiura, Kaori Denda-Nagai, Mitsuyo Takashima, Ryuichi Murakami, Shigenori Nagai, Kazuyoshi Takeda, Tatsuro Irimura: Local effects of regulatory T cells in MUC1 transgenic mice potentiate growth of MUC1 expressing tumor cells in vivo. PLoS ONE. 2012.07; 7 (9): e44770. ( PubMed , DOI )
Takeuchi Y, Nagasawa T, Katagiri S, Kitagawara S, Kobayashi H, Koyanagi T, Izumi Y: Salivary levels of antibacterial peptide (LL-37/hCAP-18) and cotinine in patients with chronic periodontitis. J Periodontol. 2012.06; 83 (6): 766-772. ( PubMed , DOI )
Akihiro Yoshizawa, Shigenori Nagai, Yukiko Baba, Taketo Yamada, Minoru Matsui, Hikaru Tanaka, Shun-ichiro Miyoshi, Masayuki Amagai, Tsutomu Yoshikawa, Keiichi Fukuda, Satoshi Ogawa, Shigeo Koyasu: Autoimmunity against M₂muscarinic acetylcholine receptor induces myocarditis and leads to a dilated cardiomyopathy-like phenotype. Eur. J. Immunol.. 2012.05; 42 (5): 1152-1163. ( PubMed , DOI )
Yutaka Kurebayashi, Shigenori Nagai, Ai Ikejiri, Masashi Ohtani, Kenji Ichiyama, Yukiko Baba, Taketo Yamada, Shohei Egami, Takayuki Hoshii, Atsushi Hirao, Satoshi Matsuda, Shigeo Koyasu: PI3K-Akt-mTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi1 expression and nuclear translocation of RORγ. Cell Rep. 2012.04; 1 (4): 360-373. ( PubMed , DOI )
Ai Ikejiri, Shigenori Nagai, Nobuhito Goda, Yutaka Kurebayashi, Mayuko Osada-Oka, Keiyo Takubo, Toshio Suda, Shigeo Koyasu: Dynamic regulation of Th17 differentiation by oxygen concentrations. Int. Immunol.. 2012.03; 24 (3): 137-146. ( PubMed , DOI )
Kouji Matsushima, Shigenori Nagai: Unraveling the mystery of the hygiene hypothesis through Helicobacter pylori infection. J. Clin. Invest.. 2012.03; 122 (3): 801-804. ( PubMed , DOI )
Atsushi Anzai, Toshihisa Anzai, Shigenori Nagai, Yuichiro Maekawa, Kotaro Naito, Hidehiro Kaneko, Yasuo Sugano, Toshiyuki Takahashi, Hitoshi Abe, Satsuki Mochizuki, Motoaki Sano, Tsutomu Yoshikawa, Yasunori Okada, Shigeo Koyasu, Satoshi Ogawa, Keiichi Fukuda: Regulatory role of dendritic cells in postinfarction healing and left ventricular remodeling. Circulation. 2012.03; 125 (10): 1234-1245. ( PubMed , DOI )
Haruki Funao, Ken Ishii, Shigenori Nagai, Aya Sasaki, Tomoyuki Hoshikawa, Mamoru Aizawa, Yasunori Okada, Kazuhiro Chiba, Shigeo Koyasu, Yoshiaki Toyama, Morio Matsumoto: Establishment of a real-time, quantitative, and reproducible mouse model of Staphylococcus osteomyelitis using bioluminescence imaging. Infect. Immun.. 2012.02; 80 (2): 733-741. ( PubMed , DOI )
Katagiri S, Nitta H, Nagasawa T, Izumi Y, Kanazawa M, Matsuo A, Chiba H, Miyazaki S, Miyauchi T, Nakamura N, Oseko F, Kanamura N, Ando Y, Hanada N, Inoue S: Reduced masticatory function in non-elderly obese Japanese adults. Obes Res Clin Pract. 2011.10; ( PubMed , DOI )
Almehdi Aslam, 青木 章, 谷口 陽一, 澤辺 正規, 江尻 健一郎, チュイ・チャントゥーン , 佐藤 郁文, 片桐 さやか, 和泉 雄一: Er:YAGレーザー照射後歯根セメント質の変化の分析(Analysis of Root Cementum Alteration following Er:YAG Laser Irradiation) 日本歯周病学会会誌. 2011.04; 53 (春季特別): 105. ( ichushi )
Sayuri Chiba, Takeshi Nagai, Toshiyuki Hayashi, Yukiko Baba, Shigenori Nagai, Shigeo Koyasu: Listerial invasion protein internalin B promotes entry into ileal Peyer's patches in vivo. Microbiol. Immunol.. 2011.02; 55 (2): 123-129. ( PubMed , DOI )
Katagiri S, Nitta H, Nagasawa T, Izumi Y, KanazawaM, Matsuo A, Chiba H, Miyazaki S, Miyauchi T, Nakamura N, Kanamura N, Ando Y, Hanada N, Inoue S: High prevalence of periodontitis in non-elderly obese Japanese adults. 2010.10; ( PubMed )
Bharti Pariksha, Katagiri Sayaka, Nitta Hiroshi, Nagasawa Toshiyuki, Kobayashi Hiroaki, Izumi Yuichi: 2型糖尿病患者において歯周治療は血清アディポネクチン値を上昇する(Periodontal treatment increases serum adiponectin level in type2 diabetes patients) 日本歯周病学会会誌. 2010.09; 52 (3): 296. ( ichushi )
Nagasawa Toshiyuki, Noda Mitsuhiko, Katagiri Sayaka, Takaichi Maki, Takahashi Yoshihiko, Wara-Aswapati Nawarat, Kobayashi Hiroaki, Ohara Satoko, Kawaguchi Yoko, Tagami Tadashi, Furuichi Yasushi, Izumi Yuichi: 歯周炎と糖尿病の関連性 悪循環を証明するための臨床研究の重要性(Relationship between Periodontitis and Diabetes: Importance of a Clinical Study to Prove the Vicious Cycle) Internal Medicine. 2010.05; 49 (10): 881-885. ( ichushi )
Nagasawa Toshiyuki, Noda Mitsuhiko, Katagiri Sayaka, Takaichi Maki, Takahashi Yoshihiko, Wara-Aswapati Nawarat, Kobayashi Hiroaki, Ohara Satoko, Kawaguchi Yoko, Tagami Tadashi, Furuichi Yasushi, Izumi Yuichi: Relationship between Periodontitis and Diabetes - Importance of a Clinical Study to Prove the Vicious Cycle INTERNAL MEDICINE. 2010; 49 (10): 881-885. ( PubMed , DOI )
Kanna Nagamatsu, Asaomi Kuwae, Tadashi Konaka, Shigenori Nagai, Sei Yoshida, Masahiro Eguchi, Mineo Watanabe, Hitomi Mimuro, Shigeo Koyasu, Akio Abe: Bordetella evades the host immune system by inducing IL-10 through a type III effector, BopN. J. Exp. Med.. 2009.12; 206 (13): 3073-3088. ( PubMed , DOI )
Tamiko Matsui, Norihito Nakata, Shigenori Nagai, Akira Nakatani, Miwako Takahashi, Toshimitsu Momose, Kuni Ohtomo, Shigeo Koyasu: Inflammatory cytokines and hypoxia contribute to 18F-FDG uptake by cells involved in pannus formation in rheumatoid arthritis. J. Nucl. Med.. 2009.06; 50 (6): 920-926. ( PubMed , DOI )
Masahisa Jinushi, Marimo Sato, Akira Kanamoto, Akihiko Itoh, Shigenori Nagai, Shigeo Koyasu, Glenn Dranoff, Hideaki Tahara: Milk fat globule epidermal growth factor-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms. J. Exp. Med.. 2009.06; 206 (6): 1317-1326. ( PubMed , DOI )
Toshiyuki Hayashi, Shigenori Nagai, Hideki Fujii, Yukiko Baba, Eiji Ikeda, Takeshi Kawase, Shigeo Koyasu: Critical roles of NK and CD8+ T cells in central nervous system listeriosis. J. Immunol.. 2009.05; 182 (10): 6360-6368. ( PubMed , DOI )
Katagiri S, Nitta H, Nagasawa T, Uchimura I, Izumiyama H, Inagaki K, Kikuchi T, Noguchi T, Kanazawa M, Matsuo A, Chiba H, Nakamura N, Kanamura N, Inoue S, Ishikawa I, Izumi Y: Multi-center intervention study on glycohemoglobin (HbA1c) and serum, high-sensitivity CRP (hs-CRP) after local anti-infectious periodontal treatment in type 2 diabetic patients with periodontal disease. Diabetes Res Clin Pract. 2009.03; 83 (3): 308-315. ( PubMed , DOI )
Masato Suzuki, Hitomi Mimuro, Kotaro Kiga, Makoto Fukumatsu, Nozomi Ishijima, Hanako Morikawa, Shigenori Nagai, Shigeo Koyasu, Robert H Gilman, Dangeruta Kersulyte, Douglas E Berg, Chihiro Sasakawa: Helicobacter pylori CagA phosphorylation-independent function in epithelial proliferation and inflammation. Cell Host Microbe. 2009.01; 5 (1): 23-34. ( PubMed , DOI )
Yumi Sawatani, Takeshi Miyamoto, Shigenori Nagai, Mikako Maruya, Jun Imai, Kana Miyamoto, Nobuyuki Fujita, Ken Ninomiya, Toru Suzuki, Ryotaro Iwasaki, Yoshiaki Toyama, Masanori Shinohara, Shigeo Koyasu, Toshio Suda: The role of DC-STAMP in maintenance of immune tolerance through regulation of dendritic cell function. Int. Immunol.. 2008.10; 20 (10): 1259-1268. ( PubMed , DOI )
Masashi Ohtani, Shigenori Nagai, Shuhei Kondo, Shinta Mizuno, Kozue Nakamura, Masanobu Tanabe, Tsutomu Takeuchi, Satoshi Matsuda, Shigeo Koyasu: Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells. Blood. 2008.08; 112 (3): 635-643. ( PubMed , DOI )
Yuichi Itoh, Mika Kamata-Sakurai, Kaori Denda-Nagai, Shigenori Nagai, Makoto Tsuiji, Katrin Ishii-Schrade, Kyoko Okada, Akiteru Goto, Masashi Fukayama, Tatsuro Irimura: Identification and expression of human epiglycanin/MUC21: a novel transmembrane mucin. Glycobiology. 2008.01; 18 (1): 74-83. ( PubMed , DOI )
Gunji T, Onouchi Y, Nagasawa T, Katagiri S, Watanabe H, Kobayashi H, Arakawa S, Noguchi K, Hata A, Izumi Y: Functional polymorphisms of the FPR1 gene and aggressive periodontitis in Japanese. Biochem Biophys Res Commun.. 2007.12; ( PubMed , DOI )
Hitomi Mimuro, Toshihiko Suzuki, Shigenori Nagai, Gabriele Rieder, Masato Suzuki, Takeshi Nagai, Yukihiro Fujita, Kanna Nagamatsu, Nozomi Ishijima, Shigeo Koyasu, Rainer Haas, Chihiro Sasakawa: Helicobacter pylori dampens gut epithelial self-renewal by inhibiting apoptosis, a bacterial strategy to enhance colonization of the stomach. Cell Host Microbe. 2007.10; 2 (4): 250-263. ( PubMed , DOI )
Shigenori Nagai, Hitomi Mimuro, Taketo Yamada, Yukiko Baba, Kazuyo Moro, Tomonori Nochi, Hiroshi Kiyono, Toshihiko Suzuki, Chihiro Sasakawa, Shigeo Koyasu: Role of Peyer's patches in the induction of Helicobacter pylori-induced gastritis. Proc. Natl. Acad. Sci. U.S.A.. 2007.05; 104 (21): 8971-8976. ( PubMed , DOI )
Yimin Yu, Shigenori Nagai, Huixia Wu, Andrew S Neish, Shigeo Koyasu, Andrew T Gewirtz: TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression. J. Immunol.. 2006.05; 176 (10): 6194-6201. ( PubMed )
Atsushi Matsuzawa, Kaoru Saegusa, Takuya Noguchi, Chiharu Sadamitsu, Hideki Nishitoh, Shigenori Nagai, Shigeo Koyasu, Kunihiro Matsumoto, Kohsuke Takeda, Hidenori Ichijo: ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity. Nat. Immunol.. 2005.06; 6 (6): 587-592. ( PubMed , DOI )
Kazushi Motomura, Nobuaki Toyoda, Kazunori Oishi, Hironori Sato, Shigenori Nagai, Shin-ichi Hashimoto, Sitefano Buguruka Tugume, Richard Enzama, Roy Mugewa, Cissy Kityo Mutuluuza, Peter Mugyeyi, Tsuyoshi Nagatake, Kouji Matsushima: Identification of a host gene subset related to disease prognosis of HIV-1 infected individuals. Int. Immunopharmacol.. 2004.12; 4 (14): 1829-1836. ( PubMed , DOI )
Nobuaki Toyoda, Shigenori Nagai, Yuya Terashima, Kazushi Motomura, Makoto Haino, Shin-ichi Hashimoto, Hajime Takizawa, Kouji Matsushima: Analysis of mRNA with microsomal fractionation using a SAGE-based DNA microarray system facilitates identification of the genes encoding secretory proteins. Genome Res.. 2003.07; 13 (7): 1728-1736. ( PubMed , DOI )
Shin-ichi Hashimoto, Shigenori Nagai, Jun Sese, Takuji Suzuki, Aya Obata, Taku Sato, Nobuaki Toyoda, Hong-Yan Dong, Makoto Kurachi, Tomoyuki Nagahata, Ken-ichi Shizuno, Shinichi Morishita, Kouji Matsushima: Gene expression profile in human leukocytes. Blood. 2003.05; 101 (9): 3509-3513. ( PubMed , DOI )
Aya Obata-Onai, Shin-ichi Hashimoto, Nobuyuki Onai, Makoto Kurachi, Shigenori Nagai, Ken-ichi Shizuno, Tomoyuki Nagahata, Kouji Matsushima, Kouji Mathushima: Comprehensive gene expression analysis of human NK cells and CD8(+) T lymphocytes. Int. Immunol.. 2002.10; 14 (10): 1085-1098. ( PubMed )
Hidekuni Inadera, Shigenori Nagai, Hong-Yan Dong, Kouji Matsushima: Molecular analysis of lipid-depleting factor in a colon-26-inoculated cancer cachexia model. Int. J. Cancer. 2002.09; 101 (1): 37-45. ( PubMed , DOI )
Sho Ishikawa, Shigenori Nagai, Taku Sato, Kenji Akadegawa, Hiroyuki Yoneyama, Yan-Yun Zhang, Nobuyuki Onai, Kouji Matsushima: Increased circulating CD11b+CD11c+ dendritic cells (DC) in aged BWF1 mice which can be matured by TNF-alpha into BLC/CXCL13-producing DC. Eur. J. Immunol.. 2002.07; 32 (7): 1881-1887. ( PubMed , DOI )
Nobuaki Higashi, Kouki Fujioka, Kaori Denda-Nagai, Shin-Ichi Hashimoto, Shigenori Nagai, Taku Sato, Yuko Fujita, Akiko Morikawa, Makoto Tsuiji, Megumi Miyata-Takeuchi, Yoshihiko Sano, Noriko Suzuki, Kazuo Yamamoto, Kouji Matsushima, Tatsuro Irimura: The macrophage C-type lectin specific for galactose/N-acetylgalactosamine is an endocytic receptor expressed on monocyte-derived immature dendritic cells. J. Biol. Chem.. 2002.06; 277 (23): 20686-20693. ( PubMed , DOI )
Makoto Kurachi, Shin-ichi Hashimoto, Aya Obata, Shigenori Nagai, Tomoyuki Nagahata, Hidekuni Inadera, Hideko Sone, Chiharu Tohyama, Shuichi Kaneko, Ken-ichi Kobayashi, Kouji Matsushima: Identification of 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive genes in mouse liver by serial analysis of gene expression. Biochem. Biophys. Res. Commun.. 2002.03; 292 (2): 368-377. ( PubMed , DOI )
S Ishikawa, T Sato, M Abe, S Nagai, N Onai, H Yoneyama, Y Zhang, T Suzuki, S Hashimoto, T Shirai, M Lipp, K Matsushima: Aberrant high expression of B lymphocyte chemokine (BLC/CXCL13) by C11b+CD11c+ dendritic cells in murine lupus and preferential chemotaxis of B1 cells towards BLC. J. Exp. Med.. 2001.06; 193 (12): 1393-1402. ( PubMed )
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M Itakura, A Tokuda, H Kimura, S Nagai, H Yoneyama, N Onai, S Ishikawa, T Kuriyama, K Matsushima: Blockade of secondary lymphoid tissue chemokine exacerbates Propionibacterium acnes-induced acute lung inflammation. J. Immunol.. 2001.02; 166 (3): 2071-2079. ( PubMed )
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T Yamashita, S Hashimoto, S Kaneko, S Nagai, N Toyoda, T Suzuki, K Kobayashi, K Matsushima: Comprehensive gene expression profile of a normal human liver. Biochem. Biophys. Res. Commun.. 2000.03; 269 (1): 110-116. ( PubMed , DOI )
S Hashimoto, T Suzuki, H Y Dong, S Nagai, N Yamazaki, K Matsushima: Serial analysis of gene expression in human monocyte-derived dendritic cells. Blood. 1999.08; 94 (3): 845-852. ( PubMed )
Ohsugi Y, Toyoshima K, Hatasa M, Shimohira T, Shiba T, Komatsu K, Tsuchiya Y, Fukuba S, Niimi H, Katagiri S, Iwata T, Aoki A: Cytological responses in periodontal tissue to photobiomodulation by low-level diode laser irradiation Journal of Japan Society for Laser Dentistry. 2023.02; 32 (3): 33-38.
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Shigenori Nagai: Acquired Immunity and Autoimmune Diseases 2015.04; 33 (2): 130-133.
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Role of PI3K/Akt/mTORC1 pathway in immune system and future prospects 2011.02; 66 (2): 293-297.
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