Cellular and Structural Physiology Laboratory (CeSPL)

137  articles.  
* There may be some overlapped articles listed due to the difference of format.

  1. Hiroki Yamaguchi, Kazutoshi Takahashi, Nobutaka Numoto, Hiroshi Suzuki, Moemi Tatsumi, Akiko Kamegawa, Kouki Nishikawa, Yasuhisa Asano, Toshimi Mizukoshi, Hiroshi Miyano, Yoshinori Fujiyoshi, Masayuki Sugiki: Open and closed structures of L-arginine oxidase by cryo-electron microscopy and X-ray crystallography. J Biochem. 2024.10; ( PubMed , DOI )

  1. Shota Suzuki, Kotaro Tanaka, Kouki Nishikawa, Hiroshi Suzuki, Atsunori Oshima, Yoshinori Fujiyoshi: Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding. Nat Commun. 2023.09; 14 (1): 5899. ( PubMed , DOI )

  2. Shunsuke Imai, Hiroshi Suzuki, Yoshinori Fujiyoshi, Ichio Shimada: Dynamically regulated two-site interaction of viral RNA to capture host translation initiation factor. Nat Commun. 2023.08; 14 (1): 4977. ( PubMed , DOI )

  3. Katsumasa Irie, Yoshinori Oda, Takashi Sumikama, Atsunori Oshima, Yoshinori Fujiyoshi: The structural basis of divalent cation block in a tetrameric prokaryotic sodium channel. Nat Commun. 2023.07; 14 (1): 4236. ( PubMed , DOI )

  4. Akiko Kamegawa, Shota Suzuki, Hiroshi Suzuki, Kouki Nishikawa, Nobutaka Numoto, Yoshinori Fujiyoshi: Structural analysis of the water channel AQP2 by single-particle cryo-EM. J Struct Biol. 2023.06; 215 107984. ( PubMed , DOI )

  5. Daisuke Kozai, Nobutaka Numoto, Kouki Nishikawa, Akiko Kamegawa, Shohei Kawasaki, Yoko Hiroaki, Katsumasa Irie, Atsunori Oshima, Hiroyuki Hanzawa, Kousei Shimada, Yutaka Kitano, Yoshinori Fujiyoshi: Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit J Mol Biol. 2023.03; 168049. ( PubMed , DOI )

  1. Yukihiro Tanimura, Yoko Hiroaki, Masahiro Mori, Yoshinori Fujiyoshi: Cell-based flow cytometry assay for simultaneous detection of multiple autoantibodies in a single serum sample. Anal Biochem. 2022.08; 650 114721. ( PubMed , DOI )

  2. Shota Suzuki, Momoko Iida, Yoko Hiroaki, Kotaro Tanaka, Akihiro Kawamoto, Takayuki Kato, Atsunori Oshima: Structural insight into the activation mechanism of MrgD with heterotrimeric Gi-protein revealed by cryo-EM. Commun Biol. 2022.07; 5 (1): 707. ( PubMed , DOI )

  3. Katerina Naydenova, Akiko Kamegawa, Mathew J Peet, Richard Henderson, Yoshinori Fujiyoshi, Christopher J Russo: On the reduction in the effects of radiation damage to two-dimensional crystals of organic and biological molecules at liquid-helium temperature. Ultramicroscopy. 2022.07; 237 113512. ( PubMed , DOI )

  4. Maki Kuzuya, Hidemi Hirano, Kenichi Hayashida, Masakatsu Watanabe, Kazumi Kobayashi, Tohru Terada, Md Iqbal Mahmood, Florence Tama, Kazutoshi Tani, Yoshinori Fujiyoshi, Atsunori Oshima: Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. Sci Signal. 2022.02; 15 (720): eabg6941. ( PubMed , DOI )

  5. Koki Kataoka, Shota Suzuki, Takeshi Tenno, Natsuko Goda, Emi Hibino, Atsunori Oshima, Hidekazu Hiroaki: A cryptic phosphate-binding pocket on the SPFH domain of human stomatin that regulates a novel fibril-like self-assembly. Curr Res Struct Biol. 2022; 4 158-166. ( PubMed , DOI )

  1. Yukako Oda, Chisato Takahashi, Shota Harada, Shun Nakamura, Daxiao Sun, Kazumi Kiso, Yuko Urata, Hitoshi Miyachi, Yoshinori Fujiyoshi, Alf Honigmann, Seiichi Uchida, Yasushi Ishihama, Fumiko Toyoshima: Discovery of anti-inflammatory physiological peptides that promote tissue repair by reinforcing epithelial barrier formation. Sci Adv. 2021.11; 7 (47): eabj6895. ( PubMed , DOI )

  2. Hiroki Yamaguchi, Akiko Kamegawa, Kunio Nakata, Tatsuki Kashiwagi, Yoshinori Fujiyoshi, Kazutoshi Tani, Toshimi Mizukoshi: Leucine Dehydrogenase: Structure and Thermostability. Subcell Biochem. 2021; 96 355-372. ( PubMed , DOI )

  1. Hanayo Nakanishi, Tomohiro Nishizawa, Katsumori Segawa, Osamu Nureki, Yoshinori Fujiyoshi, Shigekazu Nagata, Kazuhiro Abe: Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM. Cell Rep. 2020.09; 32 (13): 108208. ( PubMed , DOI )

  2. Irie Katsumasa, Shimomura Takushi, Yonekawa Yoshiki, Nagura Hitoshi, Tateyama Michihiro, Fujiyoshi Yoshinori: 天然の原核生物由来カルシウムチャネルにおけるイオン透過選択性の進化とその決定残基の同定(The selectivity determinant and evolution of a native prokaryotic voltage-dependent calcium channel) 生物物理. 2020.08; 60 (Suppl.1-2): S248. ( ichushi )

  3. Shimada Atsuhiro, Kozai Daisuke, Nishikawa Kouki, Fujiyoshi Yoshinori, Sho Gyokucho, Mizutani Takumi, Tani Kazutoshi: クライオ電子顕微鏡を用いたシトクロム酸化酵素とシトクロムcの複合体構造解析(The structural analysis of cytochrome c oxidase complexed with cytochrome c using cryo-electron microscopy) 生物物理. 2020.08; 60 (Suppl.1-2): S158. ( ichushi )

  4. Hanayo Nakanishi, Katsumasa Irie, Katsumori Segawa, Kazuya Hasegawa, Yoshinori Fujiyoshi, Shigekazu Nagata, Kazuhiro Abe: Crystal structure of a human plasma membrane phospholipid flippase. J Biol Chem. 2020.07; 295 (30): 10180-10194. ( PubMed , DOI )

  5. Koki Ikeda, Shota Suzuki, Yoshiki Shigemitsu, Takeshi Tenno, Natsuko Goda, Atsunori Oshima, Hidekazu Hiroaki: Presence of intrinsically disordered proteins can inhibit the nucleation phase of amyloid fibril formation of Aβ(1-42) in amino acid sequence independent manner. Sci Rep. 2020.07; 10 (1): 12334. ( PubMed , DOI )

  6. Development of a deep learning-based method to identify "good" regions of a cryo-electron microscopy grid. 2020.04; 12 (2): 349-354. ( PubMed , DOI )

  7. Takushi Shimomura, Yoshiki Yonekawa, Hitoshi Nagura, Michihiro Tateyama, Yoshinori Fujiyoshi, Katsumasa Irie: A native prokaryotic voltage-dependent calcium channel with a novel selectivity filter sequence. Elife. 2020.02; 9 ( PubMed , DOI )

  8. B. Burendei, R. Shinozaki, M. Watanabe, T. Terada, K. Tani, Y. Fujiyoshi and A. Oshima: Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids. Sci. Adv.. 2020.02; 6 (7): ( DOI )

  1. K. Yamamoto, V. Dubey, K. Irie, H. Nakanishi, H. Khandelia, Y. Fujiyoshi and K. Abe: A single K+-binding site in the crystal structure of the gastric proton pump. eLife. 2019.08; 8 ( DOI )

  2. Shun Nakamura, Katsumasa Irie, Hiroo Tanaka, Kouki Nishikawa, Hiroshi Suzuki, Yasunori Saitoh, Atsushi Tamura, Sachiko Tsukita & Yoshinori Fujiyoshi: Morphologic determinant of tight junctions revealed by claudin-3 structures Nature Communications. 2019.02; 10 816. ( DOI )

  3. Yamaguchi Hiroki, Kamegawa Akiko, Nakata Kunio, Kashiwagi Tatsuki, Mizukoshi Toshimi, Fujiyoshi Yoshinori, Tani Kazutoshi: Structural insights into thermostabilization of leucine dehydrogenase from its atomic structure by cryo-electron microscopy JOURNAL OF STRUCTURAL BIOLOGY. 2019.01; 205 (1): 11-21. ( PubMed , DOI )

  1. Hara-Chikuma M., Chikuma S., Kabashima K., Nakahigashi K., Kamegawa A., Fujiyoshi Y., Verkman A. S., Sugiyama Y., Inoue S., Miyachi Y.: A controlled aquaporin-3 expression in T lymphocytes regulate their migration and trafficking in cutaneous immune reaction JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2010.04; 130 S116.

  1. Yakata Kaya, Hiroaki Yoko, Ishibashi Kenichi, Sohara Eisei, Sasaki Sei, Mitsuoka Kaoru, Fujiyoshi Yoshinori: Aquaporin-11 containing a divergent NPA motif has normal water channel activity. Biochim Biophys Acta. 2007.03; 1768 (3): 688-693. ( PubMed , DOI )

  1. Abe K, Irie K, Nakanishi H, Suzuki H, Fujiyoshi Y: Crystal structures of the gastric proton pump. Nature. 2018.04; 556 (7700): 214-218. ( PubMed , DOI )

  2. Nakamura S, Fujiyoshi Y, Irie K: Enhancement of the thermostability of mouse claudin-3 on complex formation with the carboxyl-terminal region of Clostridium perfringens enterotoxin improves crystal quality. Acta crystallographica. Section F, Structural biology communications. 2018.03; 74 (Pt 3): 150-155. ( PubMed , DOI )

  3. Irie K, Haga Y, Shimomura T, Fujiyoshi Y: Optimized expression and purification of NavAb provide the structural insight into the voltage dependence. FEBS letters. 2018.01; 592 (2): 274-283. ( PubMed , DOI )

  1. Shihoya W, Nishizawa T, Yamashita K, Inoue A, Hirata K, Kadji FMN, Okuta A, Tani K, Aoki J, Fujiyoshi Y, Doi T, Nureki O: X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog. Nature structural & molecular biology. 2017.09; 24 (9): 758-764. ( PubMed , DOI )

  2. Abe K, Shimokawa J, Naito M, Munson K, Vagin O, Sachs G, Suzuki H, Tani K, Fujiyoshi Y: The cryo-EM structure of gastric H+,K+-ATPase with bound BYK99, a high-affinity member of K+-competitive, imidazo[1,2-a]pyridine inhibitors. Scientific reports. 2017.07; 7 (1): 6632. ( PubMed , DOI )

  3. Suzuki H, Tani K, Fujiyoshi Y: Crystal structures of claudins: insights into their intermolecular interactions. Annals of the New York Academy of Sciences. 2017.06; 1397 (1): 25-34. ( PubMed , DOI )

  1. Oshima A, Tani K, Fujiyoshi Y: Atomic structure of the innexin-6 gap junction channel determined by cryo-EM. Nature communications. 2016.12; 7 13681. ( PubMed , DOI )

  2. Shihoya W, Nishizawa T, Okuta A, Tani K, Dohmae N, Fujiyoshi Y, Nureki O, Doi T: Activation mechanism of endothelin ETB receptor by endothelin-1. Nature. 2016.09; 537 (7620): 363-368. ( PubMed , DOI )

  3. Shimomura T, Irie K, Fujiyoshi Y: Molecular determinants of prokaryotic voltage-gated sodium channels for recognition of local anesthetics. The FEBS journal. 2016.08; 283 (15): 2881-2895. ( PubMed , DOI )

  4. Abe K, Fujiyoshi Y: Cryo-electron microscopy for structure analyses of membrane proteins in the lipid bilayer. Current opinion in structural biology. 2016.08; 39 71-78. ( PubMed , DOI )

  5. Okuta A, Tani K, Nishimura S, Fujiyoshi Y, Doi T: Thermostabilization of the Human Endothelin Type B Receptor. Journal of molecular biology. 2016.06; 428 (11): 2265-2274. ( PubMed , DOI )

  6. Kamegawa A, Hiroaki Y, Tani K, Fujiyoshi Y: Two-dimensional crystal structure of aquaporin-4 bound to the inhibitor acetazolamide. Microscopy (Oxford, England). 2016.04; 65 (2): 177-184. ( PubMed , DOI )

  7. Nagura H, Doi T, Fujiyoshi Y: Characterization of physiological phenotypes of dentate gyrus synapses of PDZ1/2 domain-deficient PSD-95-knockin mice. The European journal of neuroscience. 2016.03; 43 (5): 618-625. ( PubMed , DOI )

  8. Oshima A, Matsuzawa T, Murata K, Tani K, Fujiyoshi Y: Hexadecameric structure of an invertebrate gap junction channel. Journal of molecular biology. 2016.03; 428 (6): 1227-1236. ( PubMed , DOI )

  9. Tanaka H, Yamamoto Y, Kashihara H, Yamazaki Y, Tani K, Fujiyoshi Y, Mineta K, Takeuchi K, Tamura A, Tsukita S: Claudin-21 Has a Paracellular Channel Role at Tight Junctions. Molecular and cellular biology. 2016.01; 36 (6): 954-964. ( PubMed , DOI )

  10. Bando Y, Irie K, Shimomura T, Umeshima H, Kushida Y, Kengaku M, Fujiyoshi Y, Hirano T, Tagawa Y: Control of Spontaneous Ca2+ Transients Is Critical for Neuronal Maturation in the Developing Neocortex. Cerebral cortex (New York, N.Y. : 1991). 2016.01; 26 (1): 106-117. ( PubMed , DOI )

  1. Hauer F, Gerle C, Fischer N, Oshima A, Shinzawa-Itoh K, Shimada S, Yokoyama K, Fujiyoshi Y, Stark H: GraDeR: Membrane Protein Complex Preparation for Single-Particle Cryo-EM. Structure (London, England : 1993). 2015.09; 23 (9): 1769-1775. ( PubMed , DOI )

  2. Minatohara K, Murata Y, Fujiyoshi Y, Doi T: An intracellular domain with a novel sequence regulates cell surface expression and synaptic clustering of leucine-rich repeat transmembrane proteins in hippocampal neurons. Journal of neurochemistry. 2015.08; 134 (4): 618-628. ( PubMed , DOI )

  3. Jiko C, Davies KM, Shinzawa-Itoh K, Tani K, Maeda S, Mills DJ, Tsukihara T, Fujiyoshi Y, Kühlbrandt W, Gerle C: Bovine F1Fo ATP synthase monomers bend the lipid bilayer in 2D membrane crystals. eLife. 2015.03; 4 e06119. ( PubMed , DOI )

  4. Saitoh Y, Suzuki H, Tani K, Nishikawa K, Irie K, Ogura Y, Tamura A, Tsukita S, Fujiyoshi Y: Tight junctions. Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin. Science (New York, N.Y.). 2015.02; 347 (6223): 775-778. ( PubMed , DOI )

  5. Suzuki H, Tani K, Tamura A, Tsukita S, Fujiyoshi Y: Model for the architecture of claudin-based paracellular ion channels through tight junctions. Journal of molecular biology. 2015.01; 427 (2): 291-297. ( PubMed , DOI )

  6. Fujiyoshi Y: Development of the field of structural physiology. Proceedings of the Japan Academy. Series B, Physical and biological sciences. 2015; 91 (9): 447-468. ( PubMed , DOI )

  1. Abe K, Tani K, Fujiyoshi Y: Systematic comparison of molecular conformations of H+,K+-ATPase reveals an important contribution of the A-M2 linker for the luminal gating. The Journal of biological chemistry. 2014.10; 289 (44): 30590-30601. ( PubMed , DOI )

  2. Tani K, Fujiyoshi Y: Water channel structures analysed by electron crystallography. Biochimica et biophysica acta. 2014.05; 1840 (5): 1605-1613. ( PubMed , DOI )

  3. Suzuki H, Nishizawa T, Tani K, Yamazaki Y, Tamura A, Ishitani R, Dohmae N, Tsukita S, Nureki O, Fujiyoshi Y: Crystal structure of a claudin provides insight into the architecture of tight junctions. Science (New York, N.Y.). 2014.04; 344 (6181): 304-307. ( PubMed , DOI )

  4. Morito D, Nishikawa K, Hoseki J, Kitamura A, Kotani Y, Kiso K, Kinjo M, Fujiyoshi Y, Nagata K: Moyamoya disease-associated protein mysterin/RNF213 is a novel AAA+ ATPase, which dynamically changes its oligomeric state. Scientific reports. 2014.03; 4 4442. ( PubMed , DOI )

  1. Yang F, Abe K, Tani K, Fujiyoshi Y: Carbon sandwich preparation preserves quality of two-dimensional crystals for cryo-electron microscopy. Microscopy (Oxford, England). 2013.12; 62 (6): 597-606. ( PubMed , DOI )

  2. Tsai CJ, Tani K, Irie K, Hiroaki Y, Shimomura T, McMillan DG, Cook GM, Schertler GF, Fujiyoshi Y, Li XD: Two alternative conformations of a voltage-gated sodium channel. Journal of molecular biology. 2013.11; 425 (22): 4074-4088. ( PubMed , DOI )

  3. Tani K, Arthur CP, Tamakoshi M, Yokoyama K, Mitsuoka K, Fujiyoshi Y, Gerle C: Visualization of two distinct states of disassembly in the bacterial V-ATPase from Thermus thermophilus. Microscopy (Oxford, England). 2013.08; 62 (4): 467-474. ( PubMed , DOI )

  4. Fujiyoshi Y, Tanji T, Osakabe N, Hirayama T: Special Issue: "Tribute to Akira Tonomura". Foreword. Microscopy (Oxford, England). 2013.06; 62 Suppl 1 S1. ( PubMed , DOI )

  5. Oshima A, Matsuzawa T, Nishikawa K, Fujiyoshi Y: Oligomeric structure and functional characterization of Caenorhabditis elegans Innexin-6 gap junction protein. The Journal of biological chemistry. 2013.04; 288 (15): 10513-10521. ( PubMed , DOI )

  6. Mori H, Fujiyoshi Y: Preface on the occasion of the inauguration issue of Microscopy. Microscopy (Oxford, England). 2013.02; 62 (1): 1-2. ( PubMed , DOI )

  7. Goda M, Fujiyoshi Y, Sugimoto M, Fujii R: Novel dichromatic chromatophores in the integument of the mandarin fish Synchiropus splendidus. The Biological bulletin. 2013.02; 224 (1): 14-17. ( PubMed , DOI )

  8. Minatohara K, Ichikawa SH, Seki T, Fujiyoshi Y, Doi T: Ligand binding of PDZ domains has various roles in the synaptic clustering of SAP102 and PSD-95. Neuroscience letters. 2013.01; 533 44-49. ( PubMed , DOI )

  9. Fujiyoshi Y: Low dose techniques and cryo-electron microscopy. Methods in molecular biology (Clifton, N.J.). 2013; 955 103-118. ( PubMed , DOI )

  10. Fujiyoshi Y: Future directions of electron crystallography. Methods in molecular biology (Clifton, N.J.). 2013; 955 551-568. ( PubMed , DOI )

  11. Suzuki H, Ito Y, Yamazaki Y, Mineta K, Uji M, Abe K, Tani K, Fujiyoshi Y, Tsukita S: The four-transmembrane protein IP39 of Euglena forms strands by a trimeric unit repeat. Nature communications. 2013; 4 1766. ( PubMed , DOI )

  1. Nagura H, Ishikawa Y, Kobayashi K, Takao K, Tanaka T, Nishikawa K, Tamura H, Shiosaka S, Suzuki H, Miyakawa T, Fujiyoshi Y, Doi T: Impaired synaptic clustering of postsynaptic density proteins and altered signal transmission in hippocampal neurons, and disrupted learning behavior in PDZ1 and PDZ2 ligand binding-deficient PSD-95 knockin mice. Molecular brain. 2012.12; 5 43. ( PubMed , DOI )

  2. Abe K, Tani K, Friedrich T, Fujiyoshi Y: Cryo-EM structure of gastric H+,K+-ATPase with a single occupied cation-binding site. Proceedings of the National Academy of Sciences of the United States of America. 2012.11; 109 (45): 18401-18406. ( PubMed , DOI )

  3. Unwin N, Fujiyoshi Y: Gating movement of acetylcholine receptor caught by plunge-freezing. Journal of molecular biology. 2012.10; 422 (5): 617-634. ( PubMed , DOI )

  4. Irie K, Shimomura T, Fujiyoshi Y: The C-terminal helical bundle of the tetrameric prokaryotic sodium channel accelerates the inactivation rate. Nature communications. 2012.04; 3 793. ( PubMed , DOI )

  1. Rico F, Oshima A, Hinterdorfer P, Fujiyoshi Y, Scheuring S: Two-dimensional kinetics of inter-connexin interactions from single-molecule force spectroscopy. Journal of molecular biology. 2011.09; 412 (1): 72-79. ( PubMed , DOI )

  2. Goda M, Ohata M, Ikoma H, Fujiyoshi Y, Sugimoto M, Fujii R: Integumental reddish-violet coloration owing to novel dichromatic chromatophores in the teleost fish, Pseudochromis diadema. Pigment cell & melanoma research. 2011.08; 24 (4): 614-617. ( PubMed , DOI )

  3. Ohta Y, Nishikawa K, Hiroaki Y, Fujiyoshi Y: Electron tomographic analysis of gap junctions in lateral giant fibers of crayfish. Journal of structural biology. 2011.07; 175 (1): 49-61. ( PubMed , DOI )

  4. Wakao S, Kitada M, Kuroda Y, Shigemoto T, Matsuse D, Akashi H, Tanimura Y, Tsuchiyama K, Kikuchi T, Goda M, Nakahata T, Fujiyoshi Y, Dezawa M: Multilineage-differentiating stress-enduring (Muse) cells are a primary source of induced pluripotent stem cells in human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 2011.06; 108 (24): 9875-9880. ( PubMed , DOI )

  5. Yakata K, Tani K, Fujiyoshi Y: Water permeability and characterization of aquaporin-11. Journal of structural biology. 2011.05; 174 (2): 315-320. ( PubMed , DOI )

  6. Fujiyoshi Y: Structural physiology based on electron crystallography. Protein science : a publication of the Protein Society. 2011.05; 20 (5): 806-817. ( PubMed , DOI )

  7. Shimomura T, Irie K, Nagura H, Imai T, Fujiyoshi Y: Arrangement and mobility of the voltage sensor domain in prokaryotic voltage-gated sodium channels. The Journal of biological chemistry. 2011.03; 286 (9): 7409-7417. ( PubMed , DOI )

  8. Abe K, Tani K, Fujiyoshi Y: Conformational rearrangement of gastric H(+),K(+)-ATPase induced by an acid suppressant. Nature communications. 2011.01; 2 155. ( PubMed , DOI )

  9. Oshima A, Tani K, Toloue MM, Hiroaki Y, Smock A, Inukai S, Cone A, Nicholson BJ, Sosinsky GE, Fujiyoshi Y: Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels. Journal of molecular biology. 2011.01; 405 (3): 724-735. ( PubMed , DOI )

  10. Fujiyoshi Y: Electron crystallography for structural and functional studies of membrane proteins. Journal of electron microscopy. 2011; 60 Suppl 1 S149-59. ( PubMed , DOI )

  1. Mitsuma T, Tani K, Hiroaki Y, Kamegawa A, Suzuki H, Hibino H, Kurachi Y, Fujiyoshi Y: Influence of the cytoplasmic domains of aquaporin-4 on water conduction and array formation. Journal of molecular biology. 2010.10; 402 (4): 669-681. ( PubMed , DOI )

  2. Matsuse D, Kitada M, Kohama M, Nishikawa K, Makinoshima H, Wakao S, Fujiyoshi Y, Heike T, Nakahata T, Akutsu H, Umezawa A, Harigae H, Kira J, Dezawa M: Human umbilical cord-derived mesenchymal stromal cells differentiate into functional Schwann cells that sustain peripheral nerve regeneration. Journal of neuropathology and experimental neurology. 2010.09; 69 (9): 973-985. ( PubMed , DOI )

  3. Nagura H, Irie K, Imai T, Shimomura T, Hige T, Fujiyoshi Y: Evidence for lateral mobility of voltage sensors in prokaryotic voltage-gated sodium channels. Biochemical and biophysical research communications. 2010.08; 399 (3): 341-346. ( PubMed , DOI )

  4. Kuroda Y, Kitada M, Wakao S, Nishikawa K, Tanimura Y, Makinoshima H, Goda M, Akashi H, Inutsuka A, Niwa A, Shigemoto T, Nabeshima Y, Nakahata T, Nabeshima Y, Fujiyoshi Y, Dezawa M: Unique multipotent cells in adult human mesenchymal cell populations. Proceedings of the National Academy of Sciences of the United States of America. 2010.05; 107 (19): 8639-8643. ( PubMed , DOI )

  5. Abe K, Tani K, Fujiyoshi Y: Structural and functional characterization of H+, K+-ATPase with bound fluorinated phosphate analogs. Journal of structural biology. 2010.04; 170 (1): 60-68. ( PubMed , DOI )

  6. Irie K, Kitagawa K, Nagura H, Imai T, Shimomura T, Fujiyoshi Y: Comparative study of the gating motif and C-type inactivation in prokaryotic voltage-gated sodium channels. The Journal of biological chemistry. 2010.02; 285 (6): 3685-3694. ( PubMed , DOI )

  7. Abe K, Tani K, Nishizawa T, Fujiyoshi Y: [Novel ratchet mechanism of gastric H(+), K(+)-ATPase revealed by electron crystallography of two-dimensional crystals]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2010.02; 130 (2): 205-210. ( PubMed , DOI )

  8. Schenk AD, Hite RK, Engel A, Fujiyoshi Y, Walz T: Electron crystallography and aquaporins. Methods in enzymology. 2010; 483 91-119. ( PubMed , DOI )

  1. Inutsuka A, Goda M, Fujiyoshi Y: Calyculin A-induced neurite retraction is critically dependent on actomyosin activation but not on polymerization state of microtubules. Biochemical and biophysical research communications. 2009.12; 390 (4): 1160-1166. ( PubMed , DOI )

  2. Noma K, Kimura K, Minatohara K, Nakashima H, Nagao Y, Mizoguchi A, Fujiyoshi Y: Triple N-glycosylation in the long S5-P loop regulates the activation and trafficking of the Kv12.2 potassium channel. The Journal of biological chemistry. 2009.11; 284 (48): 33139-33150. ( PubMed , DOI )

  3. Kuwahara Y, Unzai S, Nagata T, Hiroaki Y, Yokoyama H, Matsui I, Ikegami T, Fujiyoshi Y, Hiroaki H: Unusual thermal disassembly of the SPFH domain oligomer from Pyrococcus horikoshii. Biophysical journal. 2009.10; 97 (7): 2034-2043. ( PubMed , DOI )

  4. Fujiyoshi Y: [Observation of molecular structure of membrane proteins]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 2009.08; 54 (10): 1300-1306. ( PubMed )

  5. Abe K, Tani K, Nishizawa T, Fujiyoshi Y: Inter-subunit interaction of gastric H+,K+-ATPase prevents reverse reaction of the transport cycle. The EMBO journal. 2009.06; 28 (11): 1637-1643. ( PubMed , DOI )

  6. Tani K, Mitsuma T, Hiroaki Y, Kamegawa A, Nishikawa K, Tanimura Y, Fujiyoshi Y: Mechanism of aquaporin-4's fast and highly selective water conduction and proton exclusion. Journal of molecular biology. 2009.06; 389 (4): 694-706. ( PubMed , DOI )

  7. Tanimura Y, Hiroaki Y, Fujiyoshi Y: Acetazolamide reversibly inhibits water conduction by aquaporin-4. Journal of structural biology. 2009.04; 166 (1): 16-21. ( PubMed , DOI )

  8. Maeda S, Nakagawa S, Suga M, Yamashita E, Oshima A, Fujiyoshi Y, Tsukihara T: Structure of the connexin 26 gap junction channel at 3.5 A resolution. Nature. 2009.04; 458 (7238): 597-602. ( PubMed , DOI )

  9. Mio K, Ogura T, Yamamoto T, Hiroaki Y, Fujiyoshi Y, Kubo Y, Sato C: Reconstruction of the P2X(2) receptor reveals a vase-shaped structure with lateral tunnels above the membrane. Structure (London, England : 1993). 2009.02; 17 (2): 266-275. ( PubMed , DOI )

  10. Walz T, Fujiyoshi Y, Engel A: The AQP structure and functional implications. Handbook of experimental pharmacology. 2009; (190): 31-56. ( PubMed , DOI )

  1. Tani K, Hiroaki Y, Fujiyoshi Y: [Aquaporin-4]. Rinsho shinkeigaku = Clinical neurology. 2008.11; 48 (11): 941-944. ( PubMed )

  2. Iwasaki K, Miyazaki N, Hammar L, Zhu Y, Omura T, Wu B, Sjöborg F, Yonekura K, Murata K, Namba K, Caspar DL, Fujiyoshi Y, Cheng RH: Pleomorphic configuration of the trimeric capsid proteins of Rice dwarf virus that allows formation of both the outer capsid and tubular crystals. Journal of molecular biology. 2008.10; 383 (1): 252-265. ( PubMed , DOI )

  3. Sakisaka T, Yamamoto Y, Mochida S, Nakamura M, Nishikawa K, Ishizaki H, Okamoto-Tanaka M, Miyoshi J, Fujiyoshi Y, Manabe T, Takai Y: Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release. The Journal of cell biology. 2008.10; 183 (2): 323-337. ( PubMed , DOI )

  4. Fujiyoshi Y, Unwin N: Electron crystallography of proteins in membranes. Current opinion in structural biology. 2008.10; 18 (5): 587-592. ( PubMed , DOI )

  5. Hayakawa S, Mori M, Okuta A, Kamegawa A, Fujiyoshi Y, Yoshiyama Y, Mitsuoka K, Ishibashi K, Sasaki S, Hattori T, Kuwabara S: Neuromyelitis optica and anti-aquaporin-4 antibodies measured by an enzyme-linked immunosorbent assay. Journal of neuroimmunology. 2008.05; 196 (1-2): 181-187. ( PubMed , DOI )

  6. Oshima A, Tani K, Hiroaki Y, Fujiyoshi Y, Sosinsky GE: Projection structure of a N-terminal deletion mutant of connexin 26 channel with decreased central pore density. Cell communication & adhesion. 2008.05; 15 (1): 85-93. ( PubMed , DOI )

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