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406  articles.  
* There may be some overlapped articles listed due to the difference of format.

  1. Yusuke Fuchioka, Kentaro Endo, Yuriko Sakamaki, Takahiro Tanimoto, Nobutake Ozeki,Yusuke Nakagawa, Hideyuki Koga, Makoto Tomita, Ichiro Sekiya.: Scanning electron microscopy analysis of synovial and adipose mesenchymal stem cells adhering to cartilage Regenerative Therapy. 2024.12; 27 488-495. ( DOI )

  2. Noriko Funato, Arja Heliövaara, Cedric Boeckx: A regulatory variant impacting TBX1 expression contributes to basicranial morphology in Homo sapiens. Am J Hum Genet. 2024.04; in press ( PubMed , DOI )

  3. Mitsuru Mizuno, Koki Abe, Takashi Kakimoto, Hisashi Hasebe, Naoki Kagi, Ichiro Sekiya: Operator-derived particles and falling bacteria in biosafety cabinets. Regenarative Therapy. 2024.03; 25 264-272. ( PubMed , DOI )

  4. Mitsuru Mizuno, Yoshitaka Maeda, Sho Sanami, Takahisa Matsuzaki, Hiroshi Y Yoshikawa, Nobutake Ozeki, Hideyuki Koga, Ichiro Sekiya: Noninvasive total counting of cultured cells using a home-use scanner with a pattern sheet. iScience. 2024.03; 27 (3): 109170. ( PubMed , DOI )

  5. Yugo Miura, Kentaro Endo, Ichiro Sekiya: Histological and biochemical changes in a rat rotator cuff tear model with or without the subacromial bursa. Tissue Cell. 2024.03; 88 102370. ( PubMed , DOI )

  6. Nobuhiko Ogasawara, Yoshihito Kano, Yosuke Yoneyama, Sakurako Kobayashi, Satoshi Watanabe, Sakura Kirino, Fausto D Velez-Bravo, Yourae Hong, Aleksandra Ostapiuk, Pavlo Lutsik, Iichiroh Onishi, Shinichi Yamauchi, Yui Hiraguri, Go Ito, Yusuke Kinugasa, Kenichi Ohashi, Mamoru Watanabe, Ryuichi Okamoto, Sabine Tejpar, Shiro Yui: Discovery of non-genomic drivers of YAP signaling modulating the cell plasticity in CRC tumor lines. iScience. 2024.03; 27 (3): 109247. ( PubMed , DOI )

  7. Nobutake Ozeki, Hideyuki Koga, Tomomasa Nakamura, Yusuke Nakagawa, Takashi Hoshino, Masaki Amemiya, Ichiro Sekiya: Real-time virtual sonography-guided ossicle removal in unresolved Osgood-Schlatter disease Arthroscopy Techniques. 2024.01; ( DOI )

  1. Hisako Katano, Nobutake Ozeki, Mitsuru Mizuno, Kentaro Endo, Noriya Okanouchi 1,2, Jo Fujita, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya: Morphological analysis of three-dimensional MR images of patellofemoral joints in asymptomatic subjects Sci Rep. 2023.12; 13 (1): 16570.

  2. Mitsuru Mizuno, Koki Abe, Takashi Kakimoto, Keiichi Yano, Yukiko Ota, Kengo Tomita, Naoki Kagi, Ichiro Sekiya: Volatile organic compounds and ionic substances contamination in cell processing facilities during rest period; a preliminary assessment of exposure to cell processing operators. Regenerative Therapy. 2023.12; 24 211-218. ( PubMed , DOI )

  3. Hao Ding, Hideyuki Koga, Hiroki Katagiri, Shoichi Hasegawa, Tatushiko Anzai, Mai Katakura, Aritoshi Yoshihara, Masaki Amemiya, Takashi Hoshino, Nobutake Ozeki, Tomomasa Nakamura, Yusuke Nakagawa: Low central sensitisation inventory score is associated with better post-operative outcomes of osteotomy around the knee. Knee Surg Sports Traumatol Arthrosc. 2023.12; 31 (12): 5896-5904. ( PubMed , DOI )

  4. Ichiro Sekiya, Hisako Katano, Ali Guermazi, Yugo Miura, Noriya Okanouchi, Makoto Tomita, Jun Masumoto, Yoshio Kitazume, Hideyuki Koga, Nobutake Ozeki: Association of AI-determined Kellgren-Lawrence grade with medial meniscus extrusion and cartilage thickness by AI-based 3D MRI analysis in early knee osteoarthritis. Sci Rep. 2023.11; 13 (1): 20093. ( PubMed , DOI )

  5. Yusuke Nakagawa, Hideyuki Koga, Tomomasa Nakamura, Masafumi Horie, Hiroki Katagiri, Nobutake Ozeki, Toshiyuki Ohara, Ichiro Sekiya, Takeshi Muneta, Toshifumi Watanabe: Mid-term clinical outcomes of a posterior stabilized total knee prosthesis for Japanese patients: A minimum follow-up of 5 years. J Orthop Sci. 2023.11; 28 (6): 1325-1330. ( PubMed , DOI )

  6. Zhu Ling, Hailati Aini, Shuhei Kajikawa, Jumpei Shirakawa, Kunikazu Tsuji, Yoshinori Asou, Hideyuki Koga, Ichiro Sekiya, Akira Nifuji, Masaki Noda, Yoichi Ezura: Mutation Are Treatable by Alendronate. Pharmaceuticals (Basel). 2023.10; 16 (10): ( PubMed , DOI )

  7. Aritoshi Yoshihara, Renaud Siboni, Yusuke Nakagawa, Caroline Mouton, Christophe Jacquet, Tomomasa Nakamura, Ichiro Sekiya, Romain Seil, Hideyuki Koga: Lateral-medial asymmetry of posterior tibial slope and small lateral tibial plateau articular surface depth are morphological factors of lateral meniscus posterior root tears in ACL-injured patients. Knee Surg Sports Traumatol Arthrosc. 2023.09; 31 (9): 3594-3603. ( PubMed , DOI )

  8. Hideto Furuoka, Kentaro Endo, Ichiro Sekiya: Mesenchymal stem cells in synovial fluid increase in number in response to synovitis and display more tissue-reparative phenotypes in osteoarthritis. Stem Cell Res Ther. 2023.09; 14 (1): 244. ( PubMed , DOI )

  9. Shoichi Hasegawa, Yusuke Nakagawa, Aritoshi Yoshihara, Tomomasa Nakamura, Hiroki Katagiri, Masaya Hayashi, Hideya Yoshimura, Tsuyoshi Nagase, Ichiro Sekiya, Hideyuki Koga: Older Age, Poor Preoperative Quadriceps Muscle Strength, and Residual Pain as Risk Factors for Poor Quadriceps Muscle Strength Recovery at 1 Year After ACL Reconstruction: A TMDU MAKS Study of 402 Patients. Orthop J Sports Med. 2023.09; 11 (9): 23259671231194593. ( PubMed , DOI )

  10. Hiroki Katagiri, Yusuke Nakagawa, Yusuke Amano, Yoshiko Shirakawa, Nobutake Ozeki, Tomomasa Nakamura, Ichiro Sekiya, Hideyuki Koga: Decision regret following opening wedge high tibial osteotomy: Older age as a risk factor. Knee. 2023.06; 43 62-69. ( PubMed , DOI )

  11. Shoichi Hasegawa, Jae-Sung An, Jun Hino, Yusuke Amano, Yusuke Nakagawa, Kazumasa Miyatake, Hiroki Katagiri, Tomomasa Nakamura, Ichiro Sekiya, Hideyuki Koga, Kunikazu Tsuji: Therapeutic effect of C-type natriuretic peptide on persistent pain in a rat knee arthritis model. J Orthop Surg (Hong Kong). 2023.06; 31 (2): 10225536231181708. ( PubMed , DOI )

  12. Nobutake Ozeki, Hideyuki Koga, Yusuke Nakagawa, Hiroki Katagiri, Hisako Katano, Makoto Tomita, Jun Masumoto, Ichiro Sekiya: Association between knee cartilage thickness determined by magnetic resonance imaging three-dimensional analysis and the International Cartilage Repair Society (ICRS) arthroscopic grade. Knee. 2023.06; 42 90-98. ( PubMed , DOI )

  13. Amano Y, Ozeki N, Matsuda J, Nakamura T, Nakagawa Y, Sekiya I, Koga H: Augmentation of a Nonanatomical Repair of a Medial Meniscus Posterior Root Tear With Centralization Using Three Knotless Anchors May Be Associated With Less Meniscal Extrusion and Better Compressive Load Distribution in Mid-Flexion Compared With Non-Anatomical Root Repair Alone in a Porcine Knee Model. Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 2023.05; 39 (12): 2487-2498. ( PubMed , DOI )

  14. Misaki Yagi, Kentaro Endo, Keiichiro Komori, Ichiro Sekiya: Comparison of the effects of oxidative and inflammatory stresses on rat chondrocyte senescence. Sci Rep. 2023.05; 13 (1): 7697. ( PubMed , DOI )

  15. Sylvia Leo, Yusuke Kato, Yu Meng Wu, Mutsumi Yokota, Masato Koike, Shiro Yui, Kiichiro Tsuchiya, Nobuaki Shiraki, Shoen Kume: The effect of Vitamin D3 and Valproic Acid on the maturation of human induced pluripotent stem cell-derived enterocyte-like cells. Stem Cells. 2023.05; ( PubMed , DOI )

  16. Hiroki Katagiri, Yusuke Nakagawa, Kazumasa Miyatake, Nobutake Ozeki, Yuji Kohno, Masaki Amemiya, Ichiro Sekiya, Hideyuki Koga: Comparison of Clinical Outcomes after Revision Anterior Cruciate Ligament Reconstruction using a Bone-patellar Tendon-bone Autograft and that Using a Double-Bundle Hamstring Tendon Autograft. J Knee Surg. 2023.05; 36 (6): 613-621. ( PubMed , DOI )

  17. Yusuke Nakagawa, Kunikazu Tsuji, Tomomasa Nakamura, Hiroki Katagiri, Nobutake Ozeki, Mikio Shioda, Jae-Sung An, Ryu Yoshida, Ichiro Sekiya, Hideyuki Koga: Association of Infrapatellar Fat Pad Fibrosis at 3 Months After ACL Reconstruction With Short-term Clinical Outcomes and Inflammatory Cytokine Levels in the Synovial Fluid. Orthop J Sports Med. 2023.04; 11 (4): 23259671231164122. ( PubMed , DOI )

  18. Uchida N, Ryu Y, Takagi Y, Yoshizawa K, Suzuki K, Anraku Y, Ajioka I, Shimokawa N, Takagi M, Hoshino N, Akutagawa T, Matsubara T, Sato T, Higuchi Y, Ito H, Morita M, Muraoka T: Endocytosis-Like Vesicle Fission Mediated by a Membrane-Expanding Molecular Machine Enables Virus Encapsulation for In Vivo Delivery. Journal of the American Chemical Society. 2023.03; 145 (11): 6210-6220. ( PubMed , DOI )

  19. Ohno Y, Nakajima C, Ajioka I, Muraoka T, Yaguchi A, Fujioka T, Akimoto S, Matsuo M, Lotfy A, Nakamura S, Herranz-Pérez V, García-Verdugo JM, Matsukawa N, Kaneko N, Sawamoto K: Amphiphilic peptide-tagged N-cadherin forms radial glial-like fibers that enhance neuronal migration in injured brain and promote sensorimotor recovery. Biomaterials. 2023.03; 294 122003. ( PubMed , DOI )

  20. M Isono, H Koga, Y Nakagawa, T Nakamura, I Sekiya, H Katagiri: Inferior Healing Rate in Isolated Meniscal Repair than that in Meniscal Repair with Concomitant ACL Reconstruction Evaluated with MRI. Malays Orthop J. 2023.03; 17 (1): 61-69. ( PubMed , DOI )

  21. Ozeki N, Mizuno M, Yanada S, Okada T, Kubota R, Kushida Y, Furuoka H, Endo K, Katano H, Nakamura K, Ohya S, Koga H, Sekiya I: Autologous Synovial Mesenchymal Stem Cell Transplantation Suppresses Inflammation Caused by Synovial Harvesting and Promotes Healing in a Micro Minipig Repaired Meniscus Model. Transplantation proceedings. 2023.03; 55 (2): 470-480. ( PubMed , DOI )

  22. Mizuno M, Matsuda J, Watanabe K, Shimizu N, Sekiya I: Effect of disinfectants and manual wiping for processing the cell product changeover in a biosafety cabinet. Regenerative therapy. 2023.03; 22 169-175. ( PubMed , DOI )

  23. Mizuno Mitsuru, Yori Kouichirou, Takeuchi Toshikazu, Yamaguchi Tetsuya, Watanabe Ken, Tomaru Yasuhiro, Shimizu Norio, Sekiya Ichiro: Cross-contamination risk and decontamination during changeover after cell-product processing. Regenerative Therapy. 2023.03; 22 30-38. ( ichushi )

  24. Nobutake Ozeki, Mitsuru Mizuno, Shinobu Yanada, Takuya Okada, Rei Kubota, Yoshihisa Kushida, Hideto Furuoka, Kentaro Endo, Hisako Katano, Kentaro Nakamura, Shoji Ohya, Hideyuki Koga, Ichiro Sekiya: Autologous Synovial Mesenchymal Stem Cell Transplantation Suppresses Inflammation Caused by Synovial Harvesting and Promotes Healing in a Micro Minipig Repaired Meniscus Model. Transplant Proc. 2023.03; 55 (2): 470-480. ( PubMed , DOI )

  25. Hiroki Katagiri, Yusuke Nakagawa, Kazumasa Miyatake, Toshiyuki Ohara, Mikio Shioda, Ichiro Sekiya, Hideyuki Koga: Short-Term Outcomes after High Tibial Osteotomy Aimed at Neutral Alignment Combined with Arthroscopic Centralization of Medial Meniscus in Osteoarthritis Patients. J Knee Surg. 2023.02; 36 (3): 261-268. ( PubMed , DOI )

  26. Satoshi Watanabe, Nobuhiko Ogasawara, Sakurako Kobayashi, Sakura Kirino, Masami Inoue, Yui Hiraguri, Sayaka Nagata, Hiromichi Shimizu, Go Ito, Tomohiro Mizutani, Yasuhiro Nemoto, Kiichiro Tsuchiya, Ryuichi Okamoto, Mamoru Watanabe, Shiro Yui: Organoids transplantation as a new modality to design epithelial signature to create a membrane-protective sulfomucin-enriched segment. J Gastroenterol. 2023.02; ( PubMed , DOI )

  27. Akane Ariga, Yuji Kohno, Yusuke Nakagawa, Toshifumi Watanabe, Hiroki Katagiri, Toshiyuki Ohara, Mikio Shioda, Nobutake Ozeki, Masaki Amemiya, Atsushi Okawa, Ichiro Sekiya, Hideyuki Koga: Simultaneous bilateral total knee arthroplasty is safe and effective for patients in different ages. J Orthop Sci. 2023.01; 28 (1): 173-179. ( PubMed , DOI )

  1. Mitsuru Mizuno, Kouichirou Yori, Toshikazu Takeuchi, Tetsuya Yamaguchi, Ken Watanabe, Yasuhiro Tomaru, Norio Shimizu, Ichiro Sekiya: Cross-contamination risk and decontamination during changeover after cell-product processing. Regenerative Therapy. 2022.12; 22 30-38. ( PubMed , DOI )

  2. Shunichi Fujii, Kentaro Endo, Nobutake Ozeki, Yuriko Sakamaki, Yuji Kohno, Mitsuru Mizuno, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya: Comparison of adhesion of thawed and cultured synovial mesenchymal stem cells to the porcine meniscus and the relevance of cell surface microspikes. BMC Mol Cell Biol. 2022.12; 23 (1): 53. ( PubMed , DOI )

  3. Shunichi Fujii, Kentaro Endo, Seiya Matsuta, Keiichiro Komori, Ichiro Sekiya: Comparison of the yields and properties of dedifferentiated fat cells and mesenchymal stem cells derived from infrapatellar fat pads. Regen Ther. 2022.12; 21 611-619. ( PubMed , DOI )

  4. Mizuno Mitsuru, Sugahara Yoshimi, Iwayama Daisuke, Miyashita Noe, Katano Hisako, Sekiya Ichiro: 細胞加工オペレーターのストレスとモチベーション　オンライン質問票調査のパイロット試験(Stress and motivation of cell processing operators: A pilot study of an online questionnaire survey) Regenerative Therapy. 2022.12; 21 547-552. ( ichushi )

  5. Fujii Shunichi, Endo Kentaro, Matsuta Seiya, Komori Keiichiro, Sekiya Ichiro: 膝蓋下脂肪体由来の脱分化型脂肪細胞と間葉系幹細胞の収量と特性の比較(Comparison of the yields and properties of dedifferentiated fat cells and mesenchymal stem cells derived from infrapatellar fat pads) Regenerative Therapy. 2022.12; 21 611-619. ( ichushi )

  6. Mizuno Mitsuru, Ozeki Nobutake, Sekiya Ichiro: 変形性関節症に対する細胞療法でトリソミー7を有する培養細胞を使用する場合の安全性(Safety of using cultured cells with trisomy 7 in cell therapy for treating osteoarthritis) Regenerative Therapy. 2022.12; 21 81-86. ( ichushi )

  7. Mitsuru Mizuno, Yoshimi Sugahara, Daisuke Iwayama, Noe Miyashita, Hisako Katano, Ichiro Sekiya: Stress and motivation of cell processing operators: A pilot study of an online questionnaire survey. Regenerative Therapy. 2022.11; 21 547-552. ( PubMed , DOI )

  8. Noriko Funato*, Hiromi Yanagisawa: TBX1 targets the miR-200-ZEB2 axis to induce epithelial differentiation and inhibit stem cell properties. Scientific Reports. 2022.11; 12 (1): 20188. ( PubMed , DOI )

  9. Hideyuki Koga, Tomomasa Nakamura, Yusuke Nakagawa, Nobutake Ozeki, Takashi Hoshino, Masaki Amemiya, Ichiro Sekiya: Simultaneous Correction of Varus Deformity and Posterior Tibial Slope by Modified Hybrid Closed-Wedge High Tibial Osteotomy. Arthrosc Tech. 2022.11; 11 (11): e2081-e2089. ( PubMed , DOI )

  10. Sakurako Kobayashi, Nobuhiko Ogasawara, Satoshi Watanabe, Yosuke Yoneyama, Sakura Kirino, Yui Hiraguri, Masami Inoue, Sayaka Nagata, Yoshimi Okamoto-Uchida, Satoshi Kofuji, Hiromichi Shimizu, Go Ito, Tomohiro Mizutani, Shinichi Yamauchi, Yusuke Kinugasa, Yoshihito Kano, Yasuhiro Nemoto, Mamoru Watanabe, Kiichiro Tsuchiya, Hiroshi Nishina, Ryuichi Okamoto, Shiro Yui: Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation. Inflamm Regen. 2022.11; 42 (1): 49. ( PubMed , DOI )

  11. Ichiro Sekiya, Nobutake Ozeki: The 16th International Workshop on Osteoarthritis Imaging:“New insightson treatment and imaging: A :couple that belongs together" Osteoarthritis Imaging. 2022.10; Volume 2 (Supplement 1):

  12. Takahiro Tanimoto, Kentaro Endo, Yuriko Sakamaki, Nobutake Ozeki, Hisako Katano, Mitsuru Mizuno, Hideyuki Koga, Ichiro Sekiya: Human synovial mesenchymal stem cells show time-dependent morphological changes and increased adhesion to degenerated porcine cartilage. Scientific Reports. 2022.10; 12 (1): 16619. ( PubMed , DOI )

  13. Masaaki Isono, Jun Takeuchi, Ami Maehara, Yusuke Nakagawa, Hiroki Katagiri, Kazumasa Miyatake, Ichiro Sekiya, Hideyuki Koga, Yoshinori Asou, Kunikazu Tsuji: Effect of CD44 signal axis in the gain of mesenchymal stem cell surface antigens from synovial fibroblasts in vitro Heliyon. 2022.10; 8 (10): e10739. ( PubMed , DOI )

  14. Ichiro Sekiya, Sho Sasaki, Yugo Miura, Hayato Aoki, Hisako Katano, Noriya Okanouchi, Makoto Tomita, Jun Masumoto, Hideyuki Koga, Nobutake Ozeki: Medial Tibial Osteophyte Width Strongly Reflects Medial Meniscus Extrusion Distance and Medial Joint Space Width Moderately Reflects Cartilage Thickness in Knee Radiographs. J Magn Reson Imaging. 2022.09; 56 (3): 824-834. ( PubMed , DOI )

  15. Ichiro Sekiya, Sho Sasaki, Yugo Miura, Hayato Aoki, Hisako Katano, Noriya Okanouchi, Makoto Tomita, Jun Masumoto, Hideyuki Koga, Nobutake Ozeki: Medial tibial osteophyte width strongly reflects medial meniscus extrusion distance and medial joint space width moderately reflects cartilage thickness in knee radiographs. JMRI.(Journal of Magnetic Resonance Imaging). 2022.09; 56 (3): 824-834. ( PubMed , DOI )

  16. Hiroki Katagiri, Mikio Shioda, Yusuke Nakagawa, Toshiyuki Ohara, Nobutake Ozeki, Tomomasa Nakamura, Ichiro Sekiya, Hideyuki Koga: Risk Factors Affecting Return to Sports and Patient-Reported Outcomes After Opening-Wedge High Tibial Osteotomy in Active Patients. Orthop J Sports Med. 2022.09; 10 (9): 23259671221118836. ( PubMed , DOI )

  17. Seiji Noda, Tadashi Hosoya, Yoji Komiya, Yasuhiro Tagawa, Kentaro Endo, Keiichiro Komori, Hideyuki Koga, Yasuhiro Takahara, Kazutaka Sugimoto, Ichiro Sekiya, Tetsuya Saito, Fumitaka Mizoguchi, Shinsuke Yasuda: CD34+THY1+synovial fibroblast subset in arthritic joints has high osteoblastic and chondrogenic potentials in vitro. Arthritis Res Ther. 2022.09; 24 (1): 224. ( PubMed , DOI )

  18. Pawel J Schweiger, Marie Le Bouteiller, Shiro Yui, Malte Thodberg, Ditte Clement, Kim B Jensen: Extracellular matrix interactions provide tumor cells with an escape mechanism for commitment to differentiation. Gastroenterology. 2022.08; ( PubMed , DOI )

  19. Tsukasa Kitahashi, Ryo Kogawa, Kentaro Nakamura, Ichiro Sekiya: Integrin β1, PDGFRβ, and type II collagen are essential for meniscus regeneration by synovial mesenchymal stem cells in rats. Scientific Reports. 2022.08; 12 (1): 14148. ( PubMed , DOI )

  20. Ichiro Sekiya, Hideyuki Koga, Hisako Katano, Mitsuru Mizuno, Yuji Kohno, Koji Otabe, Nobutake Ozeki: Second-look arthroscopy after meniscus repair and synovial mesenchymal stem cell transplantation to treat degenerative flaps and radial tears of the medial meniscus: A case report. J Orthop Sci. 2022.07; 27 (4): 821-834. ( PubMed , DOI )

  21. Sekiya Ichiro, Koga Hideyuki, Katano Hisako, Mizuno Mitsuru, Kohno Yuji, Otabe Koji, Ozeki Nobutake: 半月板修復術と滑膜間葉幹細胞移植による内側半月板の変性フラップおよび橈骨断裂治療後のセカンドルック関節鏡検査　症例報告(Second-look arthroscopy after meniscus repair and synovial mesenchymal stem cell transplantation to treat degenerative flaps and radial tears of the medial meniscus: A case report) Journal of Orthopaedic Science. 2022.07; 27 (4): 821-834. ( ichushi )

  22. Yuki Taga, Yu Iwasaki, Chisa Tometsuka, Noriko Funato, Yasutaka Shigemura, Masashi Kusubata, Kazunori Mizuno: Identification of a highly stable bioactive 3-hydroxyproline-containing tripeptide in human blood after collagen hydrolysate ingestion. NPJ Sci Food. 2022.06; 6 (1): 29. ( PubMed , DOI )

  23. Muraoka T, Ajioka I: Self-assembling Molecular Medicine for the Subacute Phase of Ischemic Stroke. Neurochemical research. 2022.06; 47 (9): 2488-2498. ( PubMed , DOI )

  24. Yugo Miura, Kentaro Endo, Keiichiro Komori, Ichiro Sekiya: Clearance of senescent cells with ABT-263 improves biological functions of synovial mesenchymal stem cells from osteoarthritis patients. Stem Cell Res Ther. 2022.06; 13 (1): 222. ( PubMed , DOI )

  25. Mituru Mizuno, Nobutake Ozeki, Ichiro Sekiya: Safety of using cultured cells with trisomy 7 in cell therapy for treating osteoarthritis. Regenerative Therapy. 2022.06; 17 (21): 81-86. ( PubMed , DOI )

  26. Noriko Funato*: Craniofacial Phenotypes and Genetics of DiGeorge Syndrome. Journal Developmental Biology. 2022.05; 10 (2): 18. ( PubMed , DOI )

  27. Hirotaka Nakashima, Soshi Uchida, Akihisa Hatakeyama, Yoichi Murata, Yoshiaki Yamanaka, Manabu Tsukamoto, Ichiro Sekiya, Akinori Sakai: Isolation and Characterization of Synovial Mesenchymal Stem Cells Derived From Patients With Chronic Lateral Ankle Instability: A Comparative Analysis of Synovial Fluid, Adipose Synovium, and Fibrous Synovium of the Ankle Joint. Orthop J Sports Med. 2022.05; 10 (5): 23259671221094615. ( PubMed , DOI )

  28. Mituru Mizuno,Takahisa Matsuzaki, Nobutake Ozeki, Hisako Katano, Hideyuki Koga, Takanori Takebe, Hiroshi Yoshikawa, Ichiro Sekiya: Cell membrane fluidity and ROS resistance define DMSO tolerance of cryopreserved synovial MSCs and HUVECs. Stem Cell Research & Therapy. 2022.05; 13 (1): 177. ( PubMed , DOI )

  29. Yuji Kohno, Hideyuki Koga, Nobutake Ozeki, Junpei Matsuda, Mitsuru Mizuno, Hisako Katano, Ichiro Sekiya: Biomechanical analysis of a centralization procedure for extruded lateral meniscus after meniscectomy in porcine knee joints. Journal Orthopaedic Research. 2022.05; 40 (5): 1097-1103. ( PubMed , DOI )

  30. Guo Tang, Yoshinori Asou, Etsuko Matsumura, Yusuke Nakagawa, Kazumasa Miyatake, Hiroki Katagiri, Tomomasa Nakamura, Hideyuki Koga, Keiichiro Komori, Ichiro Sekiya, Yoich Ezura, Kunikazu Tsuji: Short cytoplasmic isoform of IL1R1/CD121a mediates IL1β induced proliferation of synovium-derived mesenchymal stem/stromal cells through ERK1/2 pathway. Heliyon. 2022.05; 8 (5): e09476. ( PubMed , DOI )

  31. Yusuke Nakagawa, Nobutake Ozeki, Hideyuki Koga: A narrative review of lateral meniscus root tears and extrusion: techniques and outcomes Annals of Joints. 2022.04; 7 (15): ( DOI )

  32. Nobutake Ozeki, Hideyuki Koga, Ichiro Sekiya: Degenerative meniscus in knee osteoarthritis: from pathology to treatment. life. 2022.04; 12 (4): 603. ( PubMed , DOI )

  33. Yuji Kohno, Mitsuru Mizuno, Kentaro Endo, Nobutake Ozeki, Hisako Katano, Mikio Matsumoto, Haruka Kaneko, Yuji Takazawa, Hideyuki Koga, Ichiro Sekiya: Yields of mesenchymal stromal cells from synovial fluid reflect those from synovium in patients with rheumatoid arthritis. Tissue and Cell. 2022.04; 75 101727. ( PubMed , DOI )

  34. Nobutake Ozeki, Hideyuki Koga, Tomomasa Nakamura, Yusuke Nakagawa, Toshiyuki Ohara, Jae-Sung An, Ichiro Sekiya: Ultrasound-assisted arthroscopic all-inside repair technique for posterior lateral meniscus tear. Arthroscopy Techniques. 2022.04; 11 (5): e929-e935. ( PubMed , DOI )

  35. Satoshi Watanabe, Sakurako Kobayashi, Nobuhiko Ogasawara, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe, Kim B Jensen, Shiro Yui: Transplantation of intestinal organoids into a mouse model of colitis. Nat Protoc. 2022.03; 17 (3): 649-671. ( PubMed , DOI )

  36. Hisako Katano, Nobutake Ozeki, Hideyuki Koga, Kenji Suzuki, Jun Masumoto, Makoto Tomita, Ichiro Sekiya: Interscan measurement error in measurements of the meniscus, including the meniscal roots, by fully automatic three-dimensional MRI analysis. Osteoarthritis Imaging. 2022.03; 2 (1): ( DOI )

  37. Hisako Katano, Nobutake Ozeki, Hideyuki Koga, Makoto Tomita, Kenji Suzuki, Jun Masumoto, Ichiro Sekiya: Three-dimensional MRI shows cartilage defect extension with no separation from the meniscus in women in their 70s with knee osteoarthritis. Sci Rep.(Scientific Reports). 2022.03; 12 (1): 4198. ( PubMed , DOI )

  38. Yugo Miura, Nobutake Ozeki, Hisako Katano, Hayato Aoki, Noriya Okanouchi, Makoto Tomita, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya: Difference in the joint space of the medial knee compartment between full extension and Rosenberg weight-bearing radiographs. Eur Radiol. 2022.03; 32 (3): 1429-1437. ( PubMed , DOI )

  39. Seiji Noda, Tadashi Hosoya, Yoji Komiya, Yasuhiro Tagawa, Kentaro Endo, Keiichiro Komori, Hideyuki Koga, Yasuhiro Takahara, Kazutaka Sugimoto, Ichiro Sekiya, Tetsuya Saito, Fumitaka Mizoguchi, Shinsuke Yasuda: synovial fibroblast subset in arthritic joints has high osteoblastic and chondrogenic potentials in vitro. Arthritis Res Ther. 2022.02; 24 (1): 45. ( PubMed , DOI )

  40. Takashi Hoshino, Yusuke Nakagawa, Kei Inomata, Toshiyuki Ohara, Hiroki Katagiri, Koji Otabe, Kanehiro Hiyama, Kenta Katagiri, Mai Katakura, Hiroko Ueki, Masaya Hayashi, Tsuyoshi Nagase, Ichiro Sekiya, Takashi Ogiuchi, Takeshi Muneta, Hideyuki Koga, : Effects of different surgical procedures for meniscus injury on two-year clinical and radiological outcomes after anterior cruciate ligament reconstructions. -TMDU MAKS study. J Orthop Sci. 2022.01; 27 (1): 199-206. ( PubMed , DOI )

  41. Hoshino Takashi, Nakagawa Yusuke, Inomata Kei, Ohara Toshiyuki, Katagiri Hiroki, Otabe Koji, Hiyama Kanehiro, Katagiri Kenta, Katakura Mai, Ueki Hiroko, Hayashi Masaya, Nagase Tsuyoshi, Sekiya Ichiro, Ogiuchi Takashi, Muneta Takeshi, Koga Hideyuki, the Tokyo Medical and Dental University(TMDU) Multicenter Arthroscopic Knee Surgery(MAKS) Group: 半月板損傷に対する異なる術式が前十字靱帯修復後の2年臨床アウトカムとX線学的アウトカムに及ぼす影響　TMDU MAKS試験(Effects of different surgical procedures for meniscus injury on two-year clinical and radiological outcomes after anterior cruciate ligament reconstructions: TMDU MAKS study) Journal of Orthopaedic Science. 2022.01; 27 (1): 199-206. ( ichushi )

  1. Nobutake Ozeki, Hideyuki Koga, Tomomasa Nakamura, Yusuke Nakagawa, Toshiyuki Ohara, Yuji Kohno, Ichiro Sekiya: Surgical Repair of Symptomatic Wrisberg Variant Discoid Lateral Mensicus with Pull-Out Repair and Capsulodesis. Arthrosc Tech. 2021.12; 11 (1): e61-e68. ( PubMed , DOI )

  2. Katsuaki Yanagisawa, Toshifumi Watanabe, Hideyuki Koga, Ichiro Sekiya, Takeshi Muneta, Tetsuya Jinno: Do the distal femur and the proximal tibia have narrower aspect ratios in smaller knees? : A morphological analysis of osteoarthritic knees in the Japanese population using computed tomography. Knee. 2021.12; 33 84-92. ( PubMed , DOI )

  3. Mitsuru Mizuno, Kentaro Endo, Hisako Katano, Naoki Amano, Masaki Nomura, Yoshinori Hasegawa, Nobutake Ozeki, Hideyuki Koga, Naoko Takasu, Osamu Ohara, Tomohiro Morio, Ichiro Sekiya: Transplantation of human autologous synovial mesenchymal stem cells with trisomy 7 into the knee joint and 5 years of follow-up. Stem Cells Transl Med. 2021.11; 10 (11): 1530-1543. ( PubMed , DOI )

  4. Atsuya Yaguchi, Mio Oshikawa, Go Watanabe, Hirotsugu Hiramatsu, Noriyuki Uchida, Chikako Hara, Naoko Kaneko, Kazunobu Sawamoto, Takahiro Muraoka, Itsuki Ajioka: Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration. Nat Commun. 2021.11; 12 (1): 6623. ( PubMed , DOI )

  5. Iwata H, Takada N, Kuroyanagi G, Ikuta K, Usami T, Sekiya I, Murakami H: Effect of hydroxyapatite tubes on the lag screw intraoperative insertion torque for the treatment of intertrochanteric femoral fractures. Injury. 2021.11; 52 (11): 3377-3381. ( PubMed , DOI )

  6. Kentaro Endo, Kiyotaka Horiuchi, Hisako Katano, Nobutake Ozeki, Yuriko Sakamaki, Hideyuki Koga, Ichiro Sekiya: Intra-articular Injection of PDGF-BB Explored in a Novel in Vitro Model Mobilizes Mesenchymal Stem Cells From the Synovium Into Synovial Fluid in Rats. Stem Cell Rev Rep. 2021.10; 17 (5): 1768-1779. ( PubMed , DOI )

  7. Hisako Katano, Nobutake Ozeki, Yuji Kohno, Yusuke Nakagawa, Hideyuki Koga, Toshifumi Watanabe, Tetsuya Jinno, Ichiro Sekiya: Trends in arthroplasty in Japan by a complete survey, 2014-2017. J Orthop Sci. 2021.09; 26 (5): 812-822. ( PubMed , DOI )

  8. Katano Hisako, Ozeki Nobutake, Kohno Yuji, Nakagawa Yusuke, Koga Hideyuki, Watanabe Toshifumi, Jinno Tetsuya, Sekiya Ichiro: 全数調査に基づいた日本での人工関節置換術の傾向　2014年〜2017年(Trends in arthroplasty in Japan by a complete survey, 2014-2017) Journal of Orthopaedic Science. 2021.09; 26 (5): 812-822. ( ichushi )

  9. Takashi Hoshino, Toshifumi Watanabe, Yusuke Nakagawa, Hiroki Katagiri, Nobutake Ozeki, Toshiyuki Ohara, Mikio Shioda, Yuji Kono, Ichiro Sekiya, Hideyuki Koga: Clinical outcomes of two-stage revision total knee arthroplasty in infected cases with antibiotic-loaded cement spacers produced using a handmade silicone mold. Knee Surg Relat Res. 2021.08; 33 (1): 27. ( PubMed , DOI )

  10. Misaki Yagi, Mitsuru Mizuno, Ryota Fujisawa, Hisako Katano, Kentaro Endo, Nobutake Ozeki, Yuriko Sakamaki, Hideyuki Koga, Ichiro Sekiya: Optimal Pore Size of Honeycomb Polylactic Acid Films for In Vitro Cartilage Formation by Synovial Mesenchymal Stem Cells. Stem Cells Int. 2021.08; eCollection 2021:9239728. ( PubMed , DOI )

  11. Toshifumi Watanabe, Kazuyoshi Gamada, Hideyuki Koga, Ichiro Sekiya, Takeshi Muneta, Tetsuya Jinno: Consistent femoral external rotation during weight-bearing knee flexion is associated with better patient-reported pain and mediolateral balance after total knee arthroplasty. Clin Biomech (Bristol, Avon). 2021.08; 88 105438. ( PubMed )

  12. Hiroko Ueki, Hiroki Katagiri, Kunikazu Tsuji, Kazumasa Miyatake, Toshifumi Watanabe, Ichiro Sekiya, Takeshi Muneta, Hideyuki Koga: Effect of transplanted mesenchymal stem cell number on the prevention of cartilage degeneration and pain reduction in a posttraumatic osteoarthritis rat model. J Orthop Sci. 2021.07; 26 (4): 690-697. ( PubMed , DOI )

  13. Kazumasa Kawata, Hideyuki Koga, Kunikazu Tsuji, Kazumasa Miyatake, Yusuke Nakagawa, Takanori Yokota, Ichiro Sekiya, Hiroki Katagiri: Extracellular vesicles derived from mesenchymal stromal cells mediate endogenous cell growth and migration via the CXCL5 and CXCL6/CXCR2 axes and repair menisci. Stem Cell Res Ther. 2021.07; 12 (1): 414. ( PubMed , DOI )

  14. Ichiro Sekiya, Hisako Katano, Mitsuru Mizuno, Hideyuki Koga, Jun Masumoto, Makoto Tomita, Nobutake Ozeki: Alterations in cartilage quantification before and after injections of mesenchymal stem cells into osteoarthritic knees. Sci Rep. 2021.07; 11 (1): 13832. ( PubMed , DOI )

  15. Motohiro Suzuki, Satoru Ishibashi, Eri Iwasawa , Takahiro Oguma, Yasuhiro Saito, Fuying Li, Shinichi Otsu, Keiko Ichinose, Kotaro Yoshioka, Tetsuya Nagata, Takanori Yokota: Effective silencing of miR-126 after ischemic stroke by means of intravenous α-tocopherol-conjugated heteroduplex oligonucleotide in mice. Sci Rep. 2021.07; 11 (1): 14237. ( PubMed , DOI )

  16. Nobutake Ozeki, Yusuke Nakagawa, Mitsuru Mizuno, Yuji Kohno, Hisako Katano, Hideyuki Koga, Ichiro Sekiya: Ultrasound-Guided Harvesting of Synovium for Regenerative Medicine of Cartilage and Meniscus Using Synovial Mesenchymal Stem Cells. Arthrosc Tech. 2021.07; 10 (7): e1723-e1727. ( PubMed , DOI )

  17. Hiroki Katagiri, Kaori Nakamura, Takeshi Muneta, Toshifumi Watanabe, Kazumasa Miyatake, Ichiro Sekiya, Hideyuki Koga, Kunikazu Tsuji: Inflammatory and healing environment in synovial fluid after anterior cruciate ligament reconstruction: Granulocytes and endogenous opioids as new targets of postoperative pain. Biochem Biophys Rep. 2021.07; 26 100981. ( PubMed , DOI )

  18. Yaguchi A, Hiramatsu H, Ishida A, Oshikawa M, Ajioka I, Muraoka T: Hydrogel-Stiffening and Non-Cell Adhesive Properties of Amphiphilic Peptides with Central Alkylene Chains. Chemistry (Weinheim an der Bergstrasse, Germany). 2021.06; 27 (36): 9295-9301. ( PubMed , DOI )

  19. Ichiro Sekiya, Yuji Kohno, Akinobu Hyodo, Hisako Katano, Keiichiro Komori, Hideyuki Koga, Makoto Tomita, Kenji Suzuki, Jun Masumoto, Nobutake Ozeki: Interscan measurement error of knee cartilage thickness and projected cartilage area ratio at 9 regions and 45 subregions by fully automatic three-dimensional MRI analysis. Eur J Radiol. 2021.06; 139 109700. ( PubMed , DOI )

  20. Go Ito, Shiro Yui, Ryuichi Okamoto: A Cellular "Hub" Function to Resolve Colitis. Cell Mol Gastroenterol Hepatol. 2021.05; ( PubMed , DOI )

  21. Kiyotaka Horiuchi, Nobutake Ozeki, Kentaro Endo, Mitsuru Mizuno, Hisako Katano, Masako Akiyama, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya: Thawed cryopreserved synovial mesenchymal stem cells show comparable effects to cultured cells in the inhibition of osteoarthritis progression in rats. Sci Rep. 2021.05; 11 (1): 9683. ( PubMed , DOI )

  22. Sheng J, Kohno S, Okada N, Okahashi N, Teranishi K, Matsuda F, Shimizu H, Linn P, Nagatani N, Yamamura M, Harada K, Horike SI, Inoue H, Yano S, Kumar S, Kitajima S, Ajioka I, Takahashi C: Treatment of Retinoblastoma 1-Intact Hepatocellular Carcinoma With Cyclin-Dependent Kinase 4/6 Inhibitor Combination Therapy. Hepatology (Baltimore, Md.). 2021.04; 74 (4): 1971-1993. ( PubMed , DOI )

  23. Ichiro Sekiya, Hisako Katano, Nobutake Ozeki: Characteristics of MSCs in Synovial Fluid and Mode of Action of Intra-Articular Injections of Synovial MSCs in Knee Osteoarthritis. Int J Mol Sci. 2021.03; 22 (6): 2838. ( PubMed , DOI )

  24. Hideyuki Koga, Tomomasa Nakamura, Yusuke Nakagawa, Nobutake Ozeki, Toshiyuki Ohara, Mikio Shioda, Yuji Kohno, Masaki Amemiya, Ichiro Sekiya: Arthroscopic Centralization Using Knotless Anchors for Extruded Medial Meniscus. Arthrosc Tech. 2021.03; 10 (3): e639-e645. ( PubMed , DOI )

  25. Toshifumi Watanabe, Kazuyoshi Gamada, Hideyuki Koga, Ichiro Sekiya, Takeshi Muneta, Tetsuya Jinno: Characteristic kinematics of floor-sitting activities after posterior-stabilized total knee arthroplasty determined using model-based shape-matching techniques. Knee. 2021.03; 29 571-579. ( PubMed , DOI )

  26. J-S An, K Tsuji, H Onuma, N Araya, M Isono, T Hoshino, K Inomata, J Hino, M Miyazato, H Hosoda, K Kangawa, Y Nakagawa, H Katagiri, K Miyatake, I Sekiya, T Muneta, H Koga: Inhibition of fibrotic changes in infrapatellar fat pad alleviates persistent pain and articular cartilage degeneration in monoiodoacetic acid-induced rat arthritis model. Osteoarthritis Cartilage. 2021.03; 29 (3): 380-388. ( PubMed , DOI )

  27. Reiko Kuno, Go Ito, Ami Kawamoto, Yui Hiraguri, Hady Yuki Sugihara, Sayaka Takeoka, Sayaka Nagata, Junichi Takahashi, Mao Tsuchiya, Sho Anzai, Tomohiro Mizutani, Hiromichi Shimizu, Shiro Yui, Shigeru Oshima, Kiichiro Tsuchiya, Mamoru Watanabe, Ryuichi Okamoto: Notch and TNF-α signaling promote cytoplasmic accumulation of OLFM4 in intestinal epithelium cells and exhibit a cell protective role in the inflamed mucosa of IBD patients. Biochem Biophys Rep. 2021.03; 25 100906. ( PubMed , DOI )

  28. Tometsuka C, Funato N, Mizuno K, Taga Y: Long-term intake of ginger protease-degraded collagen hydrolysate reduces blood lipid levels and adipocyte size in mice. Current research in food science. 2021.03; 4 175-181. ( PubMed , DOI )

  29. Weiding Cui, Yusuke Nakagawa, Hiroki Katagiri, Koji Otabe, Toshiyuki Ohara, Mikio Shioda, Yuji Kohno, Takashi Hoshino, Aritoshi Yoshihara, Ichiro Sekiya, Hideyuki Koga: Knee laxity, lateral meniscus tear and distal femur morphology influence pivot shift test grade in ACL injury patients. Knee Surg Sports Traumatol Arthrosc. 2021.02; 29 (2): 633-640. ( PubMed , DOI )

  30. Asami Yutaro, Nagata Tetsuya, Yoshioka Kotaro, Kunieda Taiki, Yoshida-Tanaka Kie, Bennett C. Frank, Seth Punit P., Yokota Takanori: Efficient Gene Suppression by DNA/DNA Double-Stranded Oligonucleotide In Vivo. Mol Ther. 2021.02; 29 (2): 838-847. ( PubMed , DOI )

  31. Tsuchiya Mao, Ito Go, Hama Minami, Nagata Sayaka, Kawamoto Ami, Suzuki Kohei, Shimizu Hiromichi, Anzai Sho, Takahashi Junichi, Kuno Reiko, Takeoka Sayaka, Hiraguri Yui, Sugihara Hady Yuki, Mizutani Tomohiro, Yui Shiro, Oshima Shigeru, Tsuchiya Kiichiro, Watanabe Mamoru, Okamoto Ryuichi: Functional analysis of isoflavones using patient-derived human colonic organoids BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2021.02; 542 40-47. ( PubMed , DOI )

  32. Nobutake Ozeki, Romain Seil, Aaron J Krych, Hideyuki Koga: Surgical treatment of complex meniscus tear and disease: state of the art. J ISAKOS. 2021.01; 6 (1): 35-45. ( PubMed , DOI )

  33. Nobutake Ozeki, Yuji Kohno, Yoshihisa Kushida, Naoto Watanabe, Mitsuru Mizuno, Hisako Katano, Jun Masumoto, Hideyuki Koga, Ichiro Sekiya: Synovial mesenchymal stem cells promote the meniscus repair in a novel pig meniscus injury model. J. Orthop. Res. 2021.01; 39 (1): 177-183. ( PubMed , DOI )

  34. Kiyotaka Horiuchi, Mitsuru Mizuno, Hisako Katano, Kentaro Endo, Nobutake Ozeki, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya.: Optimal initial cell density that yields the highest number of primary synovial mesenchymal stem cells in a clinical setting. J Med Dent Sci.. 2021.01; 68 17-26. ( DOI )

  35. Horiuchi Kiyotaka, Mizuno Mitsuru, Katano Hisako, Endo Kentaro, Ozeki Nobutake, Tsuji Kunikazu, Koga Hideyuki, Sekiya Ichiro: 臨床実地にて初代滑膜間葉系幹細胞の数が最大となるような最適な初期細胞密度(Optimal initial cell density that yields the highest number of primary synovial mesenchymal stem cells in a clinical setting) Journal of Medical and Dental Sciences. 2021; 68 17-26. ( ichushi )

  1. Yoshihisa Kushida, Nobutake Ozeki, Mitsuru Mizuno, Hisako Katano, Koji Otabe, Kunikazu Tsuji, Hideyuki Koga, Koichiro Kishima, Yoshio Soma, Ichiro Sekiya: Two- and three-dimensional optical coherence tomography to differentiate degenerative changes in a rat meniscectomy model. J Orthop Res. 2020.12; 38 (12): 2592-2600. ( PubMed , DOI )

  2. Naoto Watanabe, Kentaro Endo, Keiichiro Komori, Nobutake Ozeki, Mitsuru Mizuno, Hisako Katano, Yuji Kohno, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya.: Mesenchymal Stem Cells in Synovial Fluid Increase in Knees with Degenerative Meniscus Injury after Arthroscopic Procedures through the Endogenous Effects of CGRP and HGF. Stem cell reviews and reports.. 2020.12; 16 (6): 1305-1315. ( PubMed , DOI )

  3. Yoshie Seki, Hiroki Katagiri, Koji Otabe, Yusuke Nakagawa, Kazumasa Miyatake, Ichiro Sekiya, Hideyuki Koga: Investigation of association between the preoperative intra-articular anesthetic test and persistent pain after total knee arthroplasty. J Orthop Sci. 2020.11; 25 (6): 1055-1060. ( PubMed , DOI )

  4. Noriko Funato*, Yuki Taga, Lindsay E Laurie, Chisa Tometsuka, Masashi Kusubata, Kiyoko Ogawa-Goto: The Transcription Factor HAND1 Is Involved in Cortical Bone Mass through the Regulation of Collagen Expression. Int J Mol Sci. 2020.11; 21 (22): 8638. ( PubMed , DOI )

  5. Hideyuki Koga, Tomomasa Nakamura, Hiroki Katagiri, Yusuke Nakagawa, Nobutake Ozeki, Toshiyuki Ohara, Mikio Shioda, Yuji Kohno, Masaki Amemiya, Ichiro Sekiya: Two-Year Outcomes After Meniscoplasty by Capsular Advancement With the Application of Arthroscopic Centralization Technique for Lateral Compartment Knee Osteoarthritis. Am J Sports Med. 2020.11; 48 (13): 3154-3162.

  6. Ohyagi Masaki, Nagata Tetsuya, Ihara Kensuke, Nishi Rieko, Mabuchi Yo, Akazawa Chihiro, Yokota Takanori: DNA/RNAヘテロ二重鎖オリゴヌクレオチド技術を用いた多発性硬化症に対する新規治療戦略(New therapeutic strategy for multiple sclerosis by DNA/RNA heteroduplex oligonucleotide technology) 臨床神経学. 2020.11; 60 (Suppl.): S293. ( ichushi )

  7. Yokota Takanori, Nagata Tetsuya, Dwyer Chrissa, Yoshida Kie, Yoshioka Kotaro, Seth Punit, Rigo Frank, Bennett Frank: BBB透過性ヘテロ二重鎖オリゴヌクレオチド(HDO)の開発(Development of BBB-penetrating heteroduplex oligonucleotides(HDO)) 臨床神経学. 2020.11; 60 (Suppl.): S314. ( ichushi )

  8. Jia Chunyan, Yoshioka Kotaro, Mon Su Su Lei, Tanaka Kie, Nagata Tetsuya, Yokota Takanori: CNS疾患に対するヘテロ二重鎖オリゴヌクレオチド使用による治療指標の改善(Hetereoduplex oligonucleotides technology improves therapeutic index for CNS diseases) 臨床神経学. 2020.11; 60 (Suppl.): S323. ( ichushi )

  9. Nagata Tetsuya: BBB透過性ヘテロ二重鎖オリゴヌクレオチド(BBB-penetrating heteroduplex oligonucleotide) 臨床神経学. 2020.11; 60 (Suppl.): S255. ( ichushi )

  10. Seki Yoshie, Katagiri Hiroki, Otabe Koji, Nakagawa Yusuke, Miyatake Kazumasa, Sekiya Ichiro, Koga Hideyuki: 人工関節全置換術前の関節内麻酔テストと術後の持続性疼痛の関連の検討(Investigation of association between the preoperative intra-articular anesthetic test and persistent pain after total knee arthroplasty) Journal of Orthopaedic Science. 2020.11; 25 (6): 1055-1060. ( ichushi )

  11. Hiroyuki Yokoyama, Takashi Hirai, Tetsuya Nagata, Mitsuhiro Enomoto, Hidetoshi Kaburagi, Li Leiyo, Takayuki Motoyoshi, Toshitaka Yoshii, Atsushi Okawa, Takanori Yokota: DNA Microarray Analysis of Differential Gene Expression in the Dorsal Root Ganglia of Four Different Neuropathic Pain Mouse Models. J Pain Res. 2020.11; 13 3031-3043. ( PubMed , DOI )

  12. Hayato Aoki, Nobutake Ozeki, Hisako Katano, Akinobu Hyodo, Yugo Miura, Junpei Matsuda, Kimiko Takanashi, Kenji Suzuki, Jun Masumoto, Noriya Okanouchi, Takeo Fujiwara, Ichiro Sekiya: Relationship between medial meniscus extrusion and cartilage measurements in the knee by fully automatic three-dimensional MRI analysis. BMC Musculoskelet Disord. 2020.11; 21 (1): 742. ( PubMed , DOI )

  13. Kishimoto Y, Nakagawa O, Fujii A, Yoshioka K, Nagata T, Yokota T, Hari Y, Obika S: 2',4'-BNA/LNA with 9-(2-Aminoethoxy)-1,3-diaza-2-oxophenoxazine Efficiently Forms Duplexes and Has Enhanced Enzymatic Resistance*. Chemistry . 2020.10; 27 (7): 2427-2438. ( PubMed , DOI )

  14. N Funato*, D Srivastava, S Shibata, H Yanagisawa: TBX1 Regulates Chondrocyte Maturation in the Spheno-occipital Synchondrosis. Journal of Dental Research. 2020.09; 99 (10): 1182-1191. ( PubMed , DOI )

  15. Yoichi Murata, Soshi Uchida, Hajime Utsunomiya, Akihisa Hatakeyama, Hirotaka Nakashima, Toshiharu Mori, Yoshiaki Yamanaka, Manabu Tsukamoto, Ichiro Sekiya, Johnny Huard, Marc J Philippon, Akinori Sakai: Differentiation Potential of Synovial Mesenchymal Stem Cells Isolated From Hip Joints Affected by Femoroacetabular Impingement Syndrome Versus Osteoarthritis. Arthroscopy. 2020.08; 36 (8): 2122-2133. ( PubMed , DOI )

  16. Mitsuru Mizuno, Kentaro Endo, Hisako Katano, Ayako Tsuji, Naomi Kojima, Ken Watanabe, Norio Shimizu, Tomohiro Morio, Ichiro Sekiya: The environmental risk assessment of cell-processing facilities for cell therapy in a Japanese academic institution. PLoS ONE. 2020.08; 15 (8): e0236600. ( PubMed , DOI )

  17. Funato N*: New Insights into Cranial Synchondrosis Development: A Mini Review. Frontiers in Cell and Developmental Biology. 2020.08; 8 (706): 1-9. ( PubMed , DOI )

  18. So Suzuki, Mitsuru Mizuno, Yuriko Sakamaki, Ayako Mimata, Kentaro Endo, Yuji Kohno, Nobutake Ozeki, Koji Otabe, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya: Morphological changes in synovial mesenchymal stem cells during their adhesion to the meniscus. Lab. Invest.. 2020.07; 100 (7): 916-927. ( PubMed , DOI )

  19. Naoko Araya, Kazumasa Miyatake, Kunikazu Tsuji, Hiroki Katagiri, Yusuke Nakagawa, Takashi Hoshino, Hiroaki Onuma, Saisei An, Hirofumi Nishio, Yoshitomo Saita, Ichiro Sekiya, Hideyuki Koga: Intra-articular Injection of Pure Platelet-Rich Plasma Is the Most Effective Treatment for Joint Pain by Modulating Synovial Inflammation and Calcitonin Gene-Related Peptide Expression in a Rat Arthritis Model. Am J Sports Med. 2020.07; 48 (8): 2004-2012. ( PubMed , DOI )

  20. Hiroaki Onuma, Kunikazu Tsuji, Takashi Hoshino, Kei Inomata, Mio Udo, Yusuke Nakagawa, Hiroki Katagiri, Kazumasa Miyatake, Toshifumi Watanabe, Ichiro Sekiya, Takeshi Muneta, Hideyuki Koga: Fibrotic changes in the infrapatellar fat pad induce new vessel formation and sensory nerve fiber endings that associate prolonged pain. J. Orthop. Res.. 2020.06; 38 (6): 1296-1306. ( PubMed , DOI )

  21. Atsuya Ishida, Mio Oshikawa, Itsuki Ajioka, and Takahiro Muraoka: Sequence-Dependent Bioactivity and Self-Assembling Properties of RGD-Containing Amphiphilic Peptides as Extracellular Scaffolds ACS Applied Bio Materials. 2020.05; 3 (6): 3605-3611. ( PubMed , DOI )

  22. Rei Kubota, Hideyuki Koga, Nobutake Ozeki, Junpei Matsuda, Yuji Kohno, Mitsuru Mizuno, Hisako Katano, Ichiro Sekiya: The effect of a centralization procedure for extruded lateral meniscus on load distribution in porcine knee joints at different flexion angles. BMC Musculoskelet Disord. 2020.04; 21 (1): 205. ( PubMed , DOI )

  23. Sho Anzai, Ami Kawamoto, Sayaka Nagata, Junichi Takahashi, Mao Kawai, Reiko Kuno, Sakurako Kobayashi, Satoshi Watanabe, Kohei Suzuki, Hiromichi Shimizu, Yui Hiraguri, Sayaka Takeoka, Hady Yuki Sugihara, Shiro Yui, Shigeru Oshima, Mamoru Watanabe, Ryuichi Okamoto: TGF-β promotes fetal gene expression and cell migration velocity in a wound repair model of untransformed intestinal epithelial cells. Biochem Biophys Res Commun. 2020.04; 524 (3): 533-541. ( PubMed , DOI )

  24. Naoko Araya, Hiroki Katagiri , Yusuke Nakagawa, Toshiyuki Ohara, Mikio Shioda, Yuji Kohno, Masaki Amemiya, Ichiro Sekiya, Hideyuki Koga.: Predictors of residual mechanical symptoms after meniscus surgery: data from the maks group Osteoarthritis and Cartilage. 2020.04; 28 (1): S221-S223.

  25. Hiroki Katagiri, Kazumasa Miyatake, Toshifumi Watanabe, Masafumi Horie, Ichiro Sekiya, Takeshi Muneta, Hideyuki Koga: Validity of intraoperative observation of graft length change pattern for medial patellofemoral ligament reconstruction. J Orthop. 2020.03; 21 131-136. ( PubMed , DOI )

  26. Ryuichi Okamoto, Hiromichi Shimizu, Kohei Suzuki, Ami Kawamoto, Junichi Takahashi, Mao Kawai, Sayaka Nagata, Yui Hiraguri, Sayaka Takeoka, Hady Yuki Sugihara, Shiro Yui, Mamoru Watanabe: Organoid-based regenerative medicine for inflammatory bowel disease. Regen Ther. 2020.03; 13 1-6. ( PubMed , DOI )

  27. Masaki Amemiya, Kunikazu Tsuji, Hiroki Katagiri, Kazumasa Miyatake, Yusuke Nakagawa, Ichiro Sekiya, Takeshi Muneta, Hideyuki Koga: Synovial fluid-derived mesenchymal cells have non-inferior chondrogenic potential and can be utilized for regenerative therapy as substitute for synovium-derived cells. Biochem. Biophys. Res. Commun.. 2020.03; 523 (2): 465-472. ( PubMed , DOI )

  28. Kaori Nakamura, Tomomasa Nakamura, Masafumi Horie, Hiroki Katagiri, Koji Otabe, Yusuke Nakagawa, Masaki Amemiya, Ichiro Sekiya, Takeshi Muneta, Hideyuki Koga: Anatomic femoral tunnel placement is difficult by the transtibial technique: comparison of three different femoral tunnel drilling techniques in double-bundle anterior cruciate ligament reconstructions. Knee Surg Sports Traumatol Arthrosc. 2020.02; 28 (2): 584-593. ( PubMed , DOI )

  29. Hajime Utsunomiya, Ichiro Sekiya, Soshi Uchida.: Editorial Commentary:Are We Ready to Apply Stem Cell Therapy in Rotator Curr Tear Surgery? Arthroscopy.. 2020.01; 36 (1): 86-87. ( PubMed , DOI )

  30. Nobutake Ozeki, Hideyuki Koga, Junpei Matsuda, Yuji Kohno, Mitsuru Mizuno, Hisako Katano, Kunikazu Tsuji, Tomoyuki Saito, Takeshi Muneta, Ichiro Sekiya: Biomechanical analysis of the centralization procedure for extruded lateral menisci with posterior root deficiency in a porcine model. J Orthop Sci.. 2020.01; 25 (1): 161-166. ( PubMed , DOI )

  31. Ozeki Nobutake, Koga Hideyuki, Matsuda Junpei, Kohno Yuji, Mizuno Mitsuru, Katano Hisako, Tsuji Kunikazu, Saito Tomoyuki, Muneta Takeshi, Sekiya Ichiro: ブタモデルの後根欠損を伴う逸脱外側半月に対する中心化の生体力学的解析(Biomechanical analysis of the centralization procedure for extruded lateral menisci with posterior root deficiency in a porcine model) Journal of Orthopaedic Science. 2020.01; 25 (1): 161-166. ( ichushi )

  32. Mai Katakura, Kaori Nakamura, Toshifumi Watanabe, Masafumi Horie, Tomomasa Nakamura, Hiroki Katagiri, Koji Otabe, Yusuke Nakagawa, Toshiyuki Ohara, Ichiro Sekiya, Takeshi Muneta, Hideyuki Koga: Risk factors for residual anterolateral rotational instability after double bundle anterior cruciate ligament reconstruction: Evaluation by quantitative assessment of the pivot shift phenomenon using triaxial accelerometer. Knee. 2020.01; 27 (1): 95-101. ( PubMed , DOI )

  1. Hiroki Katagiri, Kazumasa Miyatake, Yusuke Nakagawa, Koji Otabe, Toshiyuki Ohara, Mikio Shioda, Ichiro Sekiya, Hideyuki Koga: The effect of a longitudinal tear of the medial meniscus on medial meniscal extrusion in anterior cruciate ligament injury patients. Knee. 2019.12; 26 (6): 1292-1298. ( PubMed , DOI )

  2. Ichiro Sekiya, Hideyuki Koga, Koji Otabe, Yusuke Nakagawa, Hisako Katano, Nobutake Ozeki, Mitsuru Mizuno, Masafumi Horie, Yuji Kohno, Kenta Katagiri, Naoto Watanabe, Takeshi Muneta: Additional Use of Synovial Mesenchymal Stem Cell Transplantation Following Surgical Repair of a Complex Degenerative Tear of the Medial Meniscus of the Knee: A Case Report. Cell Transplant. 2019.11; 28 (11): 1445-1454. ( PubMed , DOI )

  3. Mitsuru Mizuno, Hisako Katano, Yuri Shimozaki, Sho Sanami, Nobutake Ozeki, Hideyuki Koga, Ichiro Sekiya: Time-lapse image analysis for whole colony growth curves and daily distribution of the cell number per colony during the expansion of mesenchymal stem cells. Sci Rep. 2019.11; 9 (1): 16835. ( PubMed , DOI )

  4. Yoshioka Kotaro, Su Su Lei Mon , Jia Chunyan, Yamada Hiroki, Asami Yutaro, Tanaka Kie, Wenying Piao, Kuwahara Hiroya, Nishina Kazutaka, Nagata Tetsuya, Yokota Takanori: CNSを標的としたオーバーハングヘテロ二2本鎖核酸を用いた新しいアンチセンスオリゴヌクレオチド治療(A novel antisense oligonucleotide therapy by overhanging heteroduplex oligonucleotide targeting CNS) 臨床神経学. 2019.11; 59 (Suppl.): S408. ( ichushi )

  5. Miwa S, Okamoto H, Yamada S, Kawaguchi Y, Endo K, Aiba H, Hayashi K, Kimura H, Sekiya I, Otsuka T, Tsuchiya H: Distribution of Solitary and Multiple Enchondromas of the Hand. In vivo (Athens, Greece). 2019.11; 33 (6): 2235-2240. ( PubMed , DOI )

  6. Naoto Watanabe, Mitsuru Mizuno, Junpei Matsuda, Naoko Nakamura, Koji Otabe, Hisako Katano, Nobutake Ozeki, Yuji Kohno, Tsuyoshi Kimura, Kunikazu Tsuji, Hideyuki Koga, Akio Kishida, Ichiro Sekiya: Comparison of High-Hydrostatic-Pressure Decellularized Versus Freeze-Thawed Porcine Menisci. J. Orthop. Res.. 2019.11; 37 (11): 2466-2475. ( PubMed , DOI )

  7. Yusuke Nakagawa, Toshifumi Watanabe, Yusuke Amano, Masafumi Horie, Tomomasa Nakamura, Koji Otabe, Mai Katakura, Ichiro Sekiya, Takeshi Muneta, Hideyuki Koga: Benefit of subcutaneous patient controlled analgesia after total knee arthroplasty. Asia Pac J Sports Med Arthrosc Rehabil Technol. 2019.10; 18 18-22. ( PubMed , DOI )

  8. Akinobu Hyodo, Nobutake Ozeki, Yuji Kohno, So Suzuki, Mitsuru Mizuno, Koji Otabe, Hisako Katano, Makoto Tomita, Yusuke Nakagawa, Hideyuki Koga, Shinji Kiuchi, Kenji Suzuki, Yoshinori Itai, Jun Masumoto, Ichiro Sekiya: Projected Cartilage Area Ratio Determined by 3-Dimensional MRI Analysis: Validation of a Novel Technique to Evaluate Articular Cartilage. JB JS Open Access. 2019.10; 4 (4): e0010. ( PubMed , DOI )

  9. Komabayashi-Suzuki M, Yamanishi E, Watanabe C, Okamura M, Tabata H, Iwai R, Ajioka I, Matsushita J, Kidoya H, Takakura N, Okamoto T, Kinoshita K, Ichihashi M, Nagata KI, Ema M, Mizutani KI: Spatiotemporally Dependent Vascularization Is Differently Utilized among Neural Progenitor Subtypes during Neocortical Development. Cell reports. 2019.10; 29 (5): 1113-1129.e5. ( PubMed , DOI )

  10. Sasaki Y, Oshikawa M, Bharmoria P, Kouno H, Hayashi-Takagi A, Sato M, Ajioka I, Yanai N, Kimizuka N: Near-infrared optogenetic genome engineering based on photon upconversion hydrogels. Angewandte Chemie (International ed. in English). 2019.09; 58 (49): 17827-17833. ( PubMed , DOI )

  11. Kentaro Endo, Naoki Fujita, Takayuki Nakagawa, Ryohei Nishimura: Comparison of the effect of growth factors on chondrogenesis of canine mesenchymal stem cells. J Vet Med Sci. 2019.08; 81 (8): 1211-1218. ( PubMed , DOI )

  12. Shimpei Kondo, Yusuke Nakagawa, Mitsuru Mizuno, Kenta Katagiri, Kunikazu Tsuji, Shinji Kiuchi, Hideo Ono, Takeshi Muneta, Hideyuki Koga, Ichiro Sekiya: Transplantation of Aggregates of Autologous Synovial Mesenchymal Stem Cells for Treatment of Cartilage Defects in the Femoral Condyle and the Femoral Groove in Microminipigs. Am J Sports Med. 2019.08; 47 (10): 2338-2347. ( PubMed , DOI )

  13. Ryota Fujisawa, Mitsuru Mizuno, Hisako Katano, Koji Otabe, Nobutake Ozeki, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya: Cryopreservation in 95% serum with 5% DMSO maintains colony formation and chondrogenic abilities in human synovial mesenchymal stem cells. BMC Musculoskelet Disord. 2019.07; 20 (1): 316. ( PubMed , DOI )

  14. Ueki Hiroko, Katagiri Hiroki, Otabe Koji, Nakagawa Yusuke, Ohara Toshiyuki, Shioda Mikio, Kohno Yuji, Hoshino Takashi, Sekiya Ichiro, Koga Hideyuki: Contribution of Additional Anterolateral Structure Augmentation to Controlling Pivot Shift in Anterior Cruciate Ligament Reconstruction AMERICAN JOURNAL OF SPORTS MEDICINE. 2019.07; 47 (9): 2093-2101. ( PubMed , DOI )

  15. Ishida A, Watanabe G, Oshikawa M, Ajioka I, Muraoka T: Glycine Substitution Effects on the Supramolecular Morphology and Rigidity of Cell-Adhesive Amphiphilic Peptides. Chemistry (Weinheim an der Bergstrasse, Germany). 2019.07; 25 (59): 13523-13530. ( PubMed , DOI )

  16. Jordi Guiu, Edouard Hannezo, Shiro Yui, Samuel Demharter, Svetlana Ulyanchenko, Martti Maimets, Anne Jørgensen, Signe Perlman, Lene Lundvall, Linn Salto Mamsen, Agnete Larsen, Rasmus H Olesen, Claus Yding Andersen, Lea Langhoff Thuesen, Kristine Juul Hare, Tune H Pers, Konstantin Khodosevich, Benjamin D Simons, Kim B Jensen: Tracing the origin of adult intestinal stem cells. Nature. 2019.06; 570 (7759): 107-111. ( PubMed , DOI )

  17. Kentaro Endo, Naoki Fujita, Takayuki Nakagawa, Ryohei Nishimura: Effect of Fibroblast Growth Factor-2 and Serum on Canine Mesenchymal Stem Cell Chondrogenesis. Tissue Eng Part A. 2019.06; 25 (11-12): 901-910. ( PubMed , DOI )

  18. Naritomi Mana, Mizuno Mitsuru, Katano Hisako, Ozeki Nobutake, Otabe Koji, Komori Keiichiro, Fujii Shizuka, Ichinose Shizuko, Tsuji Kunikazu, Koga Hideyuki, Muneta Takeshi, Sekiya Ichiro.: Petaloid recombinant peptide enhances in vitro cartilage formation by synovial mesenchymal stem cells. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2019.06; 37 (6): 1350-1357. ( PubMed , DOI )

  19. Nakamura Kaori, Tsuji Kunikazu, Mizuno Mitsuru, Koga Hideyuki, Muneta Takeshi, Sekiya Ichiro: Initial cell plating density affects properties of human primary synovial mesenchymal stem cells JOURNAL OF ORTHOPAEDIC RESEARCH. 2019.06; 37 (6): 1358-1367. ( DOI )

  20. Kaori Nakamura, Kunikazu Tsuji, Mitsuru Mizuno, Hideyuki Koga, Takeshi Muneta, Ichiro Sekiya: Initial cell plating density affects properties of human primary synovial mesenchymal stem cells. J. Orthop. Res.. 2019.06; 37 (6): 1358-1367. ( PubMed , DOI )

  21. Akari Sasaki, Mitsuru Mizuno, Manabu Mochizuki, Ichiro Sekiya: Mesenchymal stem cells for cartilage regeneration in dogs. World J Stem Cells. 2019.05; 11 (5): 254-269. ( PubMed , DOI )

  22. Koga Hideyuki, Katagiri Hiroki, Ozeki Nobutake, Otabe Koji, Nakagawa Yusuke, Ohara Toshiyuki, Shioda Mikio, Kohno Yuji, Sekiya Ichiro: 半月板手術の現状　関節鏡的半月板中央配置術(Current Status of Meniscal Surgery　Arthroscopic Centralization) JOSKAS. 2019.05; 44 (4): 153. ( ichushi )

  23. Koga Hideyuki, Katagiri Hiroki, Ozeki Nobutake, Otabe Koji, Nakagawa Yusuke, Ohara Toshiyuki, Shioda Mikio, Kohno Yuji, Sekiya Ichiro: 半月板温存によるOAの予防　半月板逸脱に焦点を当てて　半月板逸脱に対する関節鏡的中央配置術(Preventing OA by Preserving Meniscus: Focusing on Meniscus Extrusion　Arthroscopic Centralization for Extruded Meniscus) JOSKAS. 2019.05; 44 (4): 557. ( ichushi )

  24. Uehara T, Choong CJ, Nakamori M, Hayakawa H, Nishiyama K, Kasahara Y, Baba K, Nagata T, Yokota T, Tsuda H, Obika S, Mochizuki H: Amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides targeting α-synuclein as a novel therapy for Parkinson's disease. Scientific reports. 2019.05; 9 (1): 7567. ( PubMed , DOI )

  25. Noda S, Kawashima N, Yamamoto M, Hashimoto K, Nara K, Sekiya I, Okiji T: Effect of cell culture density on dental pulp-derived mesenchymal stem cells with reference to osteogenic differentiation. Scientific Reports. 2019.04; 9 (1): 5430. ( PubMed , DOI )

  26. Toshifumi Watanabe, Hideyuki Koga, Hiroki Katagiri, Koji Otabe, Yusuke Nakagawa, Takeshi Muneta, Ichiro Sekiya, Tetsuya Jinno: Coronal and sagittal laxity affects clinical outcomes in posterior-stabilized total knee arthroplasty: assessment of well-functioning knees. Knee Surg Sports Traumatol Arthrosc. 2019.04; ( PubMed , DOI )

  27. Ami Kawamoto, Sayaka Nagata, Sho Anzai, Junichi Takahashi, Mao Kawai, Minami Hama, Daichi Nogawa, Kouhei Yamamoto, Reiko Kuno, Kohei Suzuki, Hiromichi Shimizu, Yui Hiraguri, Shiro Yui, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Kazuo Ohtsuka, Masanobu Kitagawa, Ryuichi Okamoto, Mamoru Watanabe: Ubiquitin D is upregulated by synergy of notch signalling and TNF-α in the inflamed intestinal epithelia of IBD patients. J Crohns Colitis. 2019.03; 13 (4): 495-509. ( PubMed , DOI )

  28. Watanabe Toshifumi, Aoki Akino, Hoshi Kenji, Muneta Takeshi, Sekiya Ichiro, Koga Hideyuki: Anterior Tibial Post Impingement during Stair Climbing: A Kinematic Analysis and Clinical Outcome J Arthroplasty. 2019.02; 34 (2): 379-384.

  29. Nakamura Tomomasa, Koga Hideyuki, Otabe Koji, Horie Masafumi, Watanabe Toshifumi, Yagishita Kazuyoshi, Sekiya Ichiro, Muneta Takeshi: 二重束前十字靱帯再建中の大腿骨孔作成に用いられる3種類のアプローチの比較　症例対照研究(Comparison of three approaches for femoral tunnel during double-bundle anterior cruciate ligament reconstruction: A case controlled study) Journal of Orthopaedic Science. 2019.01; 24 (1): 147-152. ( ichushi )

  30. Inomata Kei, Tsuji Kunikazu, Onuma Hiroaki, Hoshino Takashi, Udo Mio, Akiyama Masako, Nakagawa Yusuke, Katagiri Hiroki, Miyatake Kazumasa, Sekiya Ichiro, Muneta Takeshi, Koga Hideyuki: Time course analyses of structural changes in the infrapatellar fat pad and synovial membrane during inflammation-induced persistent pain development in rat knee joint BMC MUSCULOSKELETAL DISORDERS. 2019.01; 20 ( DOI )

  31. Inomata Kei, Tsuji Kunilazu, Onuma Hroaki, Hoshino Takashi, Udo Mio, Akiyama Masako, Nakagawa Yusuke, Katagiri Hiroki, Miyatake Kazumasa, Sekiya Ichiro, Muneta Takeshi, Koga Hideyuki: Time course analyses of structural changes in the infrapatellar fat pad and synovial membrane during inflammation-induced persistent pain development in rat knee joint BMC Musculoskelet Disord. 2019.01; 20 (8):

  32. Tomomasa Nakamura, Hideyuki Koga, Koji Otabe, Masafumi Horie, Toshifumi Watanabe, Kazuyoshi Yagishita, Ichiro Sekiya, Takeshi Muneta: Comparison of three approaches for femoral tunnel during double-bundle anterior cruciate ligament reconstruction: A case controlled study. J Orthop Sci. 2019.01; 24 (1): 147-152.

  33. Mai Katakura, Masafumi Horie, Toshifumi Watanabe, Hiroki Katagiri, Koji Otabe, Toshiyuki Ohara, Kaori Nakamura, Kenta Katagiri, Hiroko Ueki, Stefano Zaffagnini, Ichiro Sekiya, Takeshi Muneta, Hideyuki Koga: Effect of meniscus repair on pivot-shift during anterior cruciate ligament reconstruction: Objective evaluation using triaxial accelerometer. Knee. 2019.01; 26 (1): 124-131. ( PubMed , DOI )

  1. Hiroko Ueki, Yusuke Nakagawa, Toshiyuki Ohara, Toshifumi Watanabe, Masafumi Horie, Hiroki Katagiri, Koji Otabe, Kenta Katagiri, Kanehiro Hiyama, Mai Katakura, Takashi Hoshino, Kei Inomata, Naoko Araya, Ichiro Sekiya: Risk factors for residual pivot shift after anterior cruciate ligament reconstruction: data from the MAKS group. Knee Surg Sports Traumatol Arthrosc. 2018.12; 26 (12): 3724-3730. ( PubMed , DOI )

  2. Yoshiaki Masaki, Keishi Yamamoto, Takeshi Inde, Keita Yoshida, Atsuya Maruyama, Tetsuya Nagata, Jun Tanihata, Shin'ichi Takeda, Mitsuo Sekine, Kohji Seio: Synthesis of 2'-O-(N-methylcarbamoylethyl) 5-methyl-2-thiouridine and its application to splice-switching oligonucleotides. Bioorg. Med. Chem. Lett.. 2018.12; ( PubMed , DOI )

  3. Nagata Tetsuya: DNA/RNAヘテロ2本鎖核酸の最近の進歩(Recent progress of DNA/RNA heteroduplex oligonucleotide) 臨床神経学. 2018.12; 58 (Suppl.): S47. ( ichushi )

  4. Yoichi Murata, Soshi Uchida, Hajime Utsunomiya, Akihisa Hatakeyama, Hirotaka Nakashima, Angela Chang, Ichiro Sekiya, Akinori Sakai: Synovial mesenchymal stem cells derived from the cotyloid fossa synovium have higher self-renewal and differentiation potential than those from the paralabral synovium in the hip joint. American Journal of Sports Medicine. 2018.10; 46 (12): 2942-2953. ( PubMed , DOI )

  5. Kenji Rowel Q Lim*, Yusuke Echigoya*, Tetsuya Nagata*, Mutsuki Kuraoka, Masanori Kobayashi, Yoshitsugu Aoki, Terence Partridge, Rika Maruyama, Shin'ichi Takeda, Toshifumi Yokota *Equal Contribution : Efficacy of Multi-exon Skipping Treatment in Duchenne Muscular Dystrophy Dog Model Neonates. Mol. Ther.. 2018.10; ( PubMed , DOI )

  6. Kohei Suzuki, Tatsuro Murano, Hiromichi Shimizu, Go Ito, Toru Nakata, Satoru Fujii, Fumiaki Ishibashi, Ami Kawamoto, Sho Anzai, Reiko Kuno, Konomi Kuwabara, Junichi Takahashi, Minami Hama, Sayaka Nagata, Yui Hiraguri, Kento Takenaka, Shiro Yui, Kiichiro Tsuchiya, Tetsuya Nakamura, Kazuo Ohtsuka, Mamoru Watanabe, Ryuichi Okamoto: Single cell analysis of Crohn's disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties. J. Gastroenterol.. 2018.09; 53 (9): 1035-1047. ( PubMed , DOI )

  7. Nakamura T, Koga H, Otabe K, Horie M, Watanabe T, Yagishita K, Sekiya I, Muneta T: Comparison of three approaches for femoral tunnel during double-bundle anterior cruciate ligament reconstruction: A case controlled study. Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association. 2018.09; ( PubMed , DOI )

  8. Naoki Watanabe*, Tetsuya Nagata*, Youhei Satou, Satoru Masuda, Takashi Saito, Hidetoshi Kitagawa, Hirofumi Komaki, Kazuchika Takagaki, Shin'ichi Takeda *Equal Contribution: NS-065/NCNP-01: An Antisense Oligonucleotide for Potential Treatment of Exon 53 Skipping in Duchenne Muscular Dystrophy. Mol Ther Nucleic Acids. 2018.09; 13 442-449. ( PubMed , DOI )

  9. *Noriko Funato, Hiromi Yanagisawa: Deletion of the T-box transcription factor gene, Tbx1, in mice induces differential expression of genes associated with cleft palate in humans. Archives of Oral Biology. 2018.08; 95 149-155. ( PubMed , DOI )

  10. Akari Sasaki, Mitsuru Mizuno, Nobutake Ozeki, Hisako Katano, Koji Otabe, Kunikazu Tsuji, Hideyuki Koga, Manabu Mochizuki, Ichiro Sekiya: Canine mesenchymal stem cells from synovium have a higher chondrogenic potential than those from infrapatellar fat pad, adipose tissue, and bone marrow. PLoS ONE. 2018.08; 13 (8): e0202922. ( PubMed , DOI )

  11. Takashi Hoshino, Kunikazu Tsuji, Hiroaki Onuma, Mio Udo, Hiroko Ueki, Masako Akiyama, Kahaer Abula, Hiroki Katagiri, Kazumasa Miyatake, Toshihumi Watanabe, Ichiro Sekiya, Hideyuki Koga, Takeshi Muneta: Persistent synovial inflammation plays important roles in persistent pain development in the rat knee before cartilage degradation reaches the subchondral bone. BMC Musculoskelet Disord. 2018.08; 19 (1): 291. ( PubMed , DOI )

  12. Yuki Taga, Masashi Kusubata, Kiyoko Ogawa-Goto, Shunji Hattori, and Noriko Funato: Collagen-derived X-Hyp-Gly-type tripeptides promote differentiation of MC3T3-E1 pre-osteoblasts Journal of Functional Foods. 2018.07; 46 456-462. ( DOI )

  13. Katano H, Koga H, Ozeki N, Otabe K, Mizuno M, Tomita M, Muneta T, Sekiya I.: Trends in isolated meniscus repair and meniscectomy in Japan, 2011-2016. PLoS ONE. 2018.07; 23 (4): 676-681. ( PubMed )

  14. Katano Hisako, Koga Hideyuki, Ozeki Nobutake, Otabe Koji, Mizuno Mitsuru, Tomita Makoto, Muneta Takeshi, Sekiya Ichiro: 日本における2011〜2016年の分離半月板修復術と半月板切除術の傾向(Trends in isolated meniscus repair and meniscectomy in Japan, 2011-2016) Journal of Orthopaedic Science. 2018.07; 23 (4): 676-681. ( ichushi )

  15. Ogata Yusuke, Mabuchi Yo, Shinoda Kosuke, Horiike Yuta, Mizuno Mitsuru, Otabe Koji, Suto Eriko Grace, Suzuki Nobuharu, Sekiya Ichiro, Akazawa Chihiro: Anterior cruciate ligament-derived mesenchymal stromal cells have a propensity to differentiate into the ligament lineage(和訳中) Regenerative Therapy. 2018.06; 8 20-28. ( ichushi )

  16. Uomizu Mari, Muneta Takeshi, Ojima Miyoko, Sekiya Ichiro, Koga Hideyuki, Tsuji Kunikazu: PDGFが誘導する滑膜間葉系幹細胞の増殖と分化はPI3K-PKB/Akt経路によって媒介されている(PDGF-induced proliferation and differentiation of synovial mesenchymal stem cells is mediated by the PI3K-PKB/Akt pathway) Journal of Medical and Dental Sciences. 2018.06; 65 (2): 73-82. ( ichushi )

  17. Mari Uomizu, Takeshi Muneta, Miyoko Ojima, Ichiro Sekiya, Hideyuki Koga, Kunikazu Tsuji: PDGF-induced proliferation and differentiation of synovial mesenchymal stem cells is mediated by the PI3K-PKB/Akt pathway. J Med Dent Sci. 2018.06; 65 (2): 73-82.

  18. Mindae Kim, Watanabe Toshifumi, Muneta Takeshi, Ohara Toshiyuki, Sekiya Ichiro, Koga Hideyuki: Coronal Instability after Total Knee Arthroplasty using Bi-Surface type 3: An Averaged 10 Year Follow-up Study(和訳中) Journal of Medical and Dental Sciences. 2018.06; 65 (2): 51-58. ( ichushi )

  19. Ogata Yusuke, Mabuchi Yo, Shinoda Kosuke, Horiike Yuta, Mizuno Mitsuru, Otabe Koji, Suto Eriko Grace, Suzuki Nobuharu, Sekiya Ichiro, Akazawa Chihiro: Anterior cruciate ligament-derived mesenchymal stromal cells have a propensity to differentiate into the ligament lineage Regenerative Medicine. 2018.06; 8 20-28. ( PubMed , DOI )

  20. Mitsuru Mizuno, Hisako Katano, Yo Mabuchi, Yusuke Ogata, Shizuko Ichinose, Shizuka Fujii, Koji Otabe, Keiichiro Komori, Nobutake Ozeki, Hideyuki Koga, Kunikazu Tsuji, Chihiro Akazawa, Takeshi Muneta, Ichiro Sekiya: Specific markers and properties of synovial mesenchymal stem cells in the surface, stromal, and perivascular regions. Stem Cell Research & Therapy. 2018.05; 9 (1): 123. ( PubMed , DOI )

  21. Nam Eunryel, Fujita Naoki, Morita Maresuke, Lin Hsing-Yi, Endo Kentaro, Nakagawa Takayuki, Nishimura Ryohei, Tsuzuki Keiko: A pilot study of transplantation of an autologous corneal epithelial cell sheet in a canine model of corneal injury JAPANESE JOURNAL OF VETERINARY RESEARCH. 2018.05; 66 (2): 83-92. ( DOI )

  22. Sekiya Ichiro, Koga Hideyuki, Otabe Koji, Nakagawa Yusuke, Katano Hisako, Ozeki Nobutake, Mizuno Mitsuru, Horie Masafumi, Muneta Takeshi: Regenerative medicine in Knee 変性半月板断裂に対する修復+滑膜幹細胞移植の2年成績(Regenerative medicine in Knee Transplantation of synovial stem cells onto degenerative torn meniscus: a 2-year follow-up study) JOSKAS. 2018.05; 43 (4): 171. ( ichushi )

  23. Minami Takao, Koga Hideyuki, Sekiya Ichiro, Watanabe Toshifumi, Horie Masafumi, Katagiri Hiroki, Otabe Koji, Ohara Toshiyuki, Katakura Mai, Muneta Takeshi: Posteriorly inserted anterior cruciate ligament in knees with discoid lateral meniscus corresponding to bony morphological characteristics of femoral lateral condyle JOURNAL OF ORTHOPAEDIC SCIENCE. 2018.03; 23 (2): 350-355. ( PubMed )

  24. Kanehiro Hiyama, Yusuke Nakagawa, Toshiyuki Ohara, Takeshi Muneta, Toshifumi Watanabe, Masafumi Horie, Koji Otabe, Hiroki Katagiri, Kenta Katagiri, Mai Katakura, Takashi Hoshino, Hiroko Ueki, Kei Inomata, Naoko Araya, Ichiro Sekiya, Hideyuki Koga: Anterior cruciate ligament injuries result in a larger functional deficit in fighting sport athletes: comparison of functional status among different sport types. Journal of ISAKOS. 2018.03; (3): 128-133.

  25. Hiroya Kuwahara, Jindong Song, Takahiro Shimoura, Kie Yoshida-Tanaka, Tadahaya Mizuno, Tatsuki Mochizuki, Satoshi Zeniya, Fuying Li, Kazutaka Nishina, Tetsuya Nagata, Shingo Ito, Hiroyuki Kusuhara, Takanori Yokota: Modulation of blood-brain barrier function by a heteroduplex oligonucleotide in vivo. Sci Rep. 2018.03; 8 (1): 4377. ( PubMed , DOI )

  26. Ken Watanabe, Koji Otabe, Norio Shimizu, Keiichirou Komori, Mitsuru Mizuno, Hisako Katano, Hideyuki Koga, Ichiro Sekiya: High-sensitivity virus and mycoplasma screening test reveals high prevalence of parvovirus B19 infection in human synovial tissues and bone marrow. Stem Cell Res Ther. 2018.03; 9 (1): 80. ( PubMed , DOI )

  27. Yuji Kohno, Mitsuru Mizuno, Nobutake Ozeki, Hisako Katano, Koji Otabe, Hideyuki Koga, Mikio Matsumoto, Haruka Kaneko, Yuji Takazawa, Ichiro Sekiya: Comparison of mesenchymal stem cells obtained by suspended culture of synovium from patients with rheumatoid arthritis and osteoarthritis. BMC Musculoskelet Disord. 2018.03; 19 (1): 78. ( PubMed , DOI )

  28. Minami Takao, Koga Hideyuki, Sekiya Ichiro, Watanabe Toshifumi, Horie Masafumi, Katagiri Hiroki, Otabe Koji, Ohara Toshiyuki, Katakura Mai, Muneta Takeshi: 円板状外側半月板のある膝に対して大腿骨外側顆の骨形態学的特徴に応じて後方から挿入された前十字靱帯(Posteriorly inserted anterior cruciate ligament in knees with discoid lateral meniscus corresponding to bony morphological characteristics of femoral lateral condyle) Journal of Orthopaedic Science. 2018.03; 23 (2): 350-355. ( ichushi )

  29. F P Luyten, S Bierma-Zeinstra, F Dell'Accio, V B Kraus, K Nakata, I Sekiya, N K Arden, L S Lohmander: Toward classification criteria for early osteoarthritis of the knee. Semin. Arthritis Rheum.. 2018.02; 47 (4): 457-463. ( PubMed , DOI )

  30. Kana Ishii, Hidetoshi Sakurai, Nobuharu Suzuki, Yo Mabuchi, Ichiro Sekiya, Kiyotoshi Sekiguchi, Chihiro Akazawa: Recapitulation of Extracellular LAMININ Environment Maintains Stemness of Satellite Cells In Vitro. Stem Cell Reports. 2018.02; 10 (2): 568-582. ( PubMed , DOI )

  31. Takuya Oyaizu, Mitsuhiro Enomoto, Naoki Yamamoto, Kunikazu Tsuji, Masaki Horie, Takeshi Muneta, Ichiro Sekiya, Atsushi Okawa, Kazuyoshi Yagishita: Hyperbaric oxygen reduces inflammation, oxygenates injured muscle, and regenerates skeletal muscle via macrophage and satellite cell activation. Sci Rep. 2018.01; 8 (1): 1288. ( PubMed , DOI )

  32. Shiro Yui, Luca Azzolin, Martti Maimets, Marianne Terndrup Pedersen, Robert P Fordham, Stine L Hansen, Hjalte L Larsen, Jordi Guiu, Mariana R P Alves, Carsten F Rundsten, Jens V Johansen, Yuan Li, Chris D Madsen, Tetsuya Nakamura, Mamoru Watanabe, Ole H Nielsen, Pawel J Schweiger, Stefano Piccolo, Kim B Jensen: YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration. Cell Stem Cell. 2018.01; 22 (1): 35-49.e7. ( PubMed , DOI )

  33. Hideo Jinnou, Masato Sawada, Koya Kawase, Naoko Kaneko, Vicente Herranz-Pérez, Takuya Miyamoto, Takumi Kawaue, Takaki Miyata, Yasuhiko Tabata, Toshihiro Akaike, José Manuel García-Verdugo, Itsuki Ajioka, Shinji Saitoh, Kazunobu Sawamoto: Radial Glial Fibers Promote Neuronal Migration and Functional Recovery after Neonatal Brain Injury. Cell Stem Cell. 2018.01; 22 (1): 128-137. ( PubMed , DOI )

  1. Ishii Kana, Suzuki Nobuharu, Mabuchi Yo, Sekiya Ichiro, Akazawa Chihiro: Technical advantage of recombinant collagenase for isolation of muscle stem cells REGENERATIVE THERAPY. 2017.12; 7 1-7. ( PubMed , DOI )

  2. Ishii Kana, Suzuki Nobuharu, Mabuchi Yo, Sekiya Ichiro, Akazawa Chihiro: Technical advantage of recombinant collagenase for isolation of muscle stem cells(和訳中) Regenerative Therapy. 2017.12; 7 1-7. ( ichushi )

  3. Sekiya I, Kobayashi M, Okamoto H, Otsuka T: Progress and Role of Finger Joint Arthroscopy. Hand clinics. 2017.11; 33 (4): 819-829. ( PubMed , DOI )

  4. Yuki Kishimoto, Akane Fujii, Osamu Nakagawa, Tetsuya Nagata, Takanori Yokota, Yoshiyuki Hari, Satoshi Obika: Synthesis and thermal stabilities of oligonucleotides containing 2'-O,4'-C-methylene bridged nucleic acid with a phenoxazine base. Org. Biomol. Chem.. 2017.10; 15 (38): 8145-8152. ( PubMed , DOI )

  5. Uehara T., Choong C. J., Hayakawa H., Kasahara Y., Nagata T., Yokota T., Baba K., Nakamori M., Obika S., Mochizuki H.: Antisense oligonucleotides containing amido-bridged nucleic acid reduce SNCA expression and improve motor function in Parkinson's disease animal models JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 1044-1045. ( DOI )

  6. Yoshioka K., Kunieda T., Asami Y., Sujino Y., Tanaka K., Piao W., Kuwahara H., Nishina K., Nagata T., Yokota T.: Dual overhanging-duplex oligonucleotide improved efficacy and safety in gene therapy for FAP JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 140. ( DOI )

  7. Ichiro Sekiya, Darwin J.Prockop.: Beginning of an Unresolved Debate:Should Mesenchymal Stem Cells Be Expanded at Low Density to Preserve Early Progenitors? STEM CELLS 35Anniversary. 2017.09; 1 36-37.

  8. Nakagawa Y, Muneta T, Watanabe T, Horie M, Nakamura T, Otabe K, Katakura M, Sumi Y, Sekiya I, Koga H: Arthroscopic centralization achieved good clinical improvements and radiographic outcomes in a rugby player with osteoarthritis after subtotal lateral meniscectomy: A case report. Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association. 2017.09; 25 (3): 537-543. ( PubMed , DOI )

  9. Mio Oshikawa, Kei Okada, Hidenori Tabata, Koh-Ichi Nagata, Itsuki Ajioka: Dnmt1-dependent Chk1 pathway suppression is protective against neuron division. Development. 2017.09; 144 (18): 3303-3314. ( PubMed , DOI )

  10. Kaori Nakamura, Hideyuki Koga, Ichiro Sekiya, Toshifumi Watanabe, Tomoyuki Mochizuki, Masafumi Horie, Tomomasa Nakamura, Koji Otabe, Takeshi Muneta: Evaluation of pivot shift phenomenon while awake and under anaesthesia by different manoeuvres using triaxial accelerometer. Knee Surg Sports Traumatol Arthrosc. 2017.08; 25 (8): 2377-2383. ( PubMed , DOI )

  11. Hideyuki Koga, Toshifumi Watanabe, Masafumi Horie, Hiroki Katagiri, Koji Otabe, Toshiyuki Ohara, Mai Katakura, Ichiro Sekiya, Takeshi Muneta: Augmentation of the pullout repair of a medialmeniscus posterior root tear by arthroscopic centralization 2017.08; 6 (4): e1335-e1339. ( PubMed )

  12. Kei Inomata, Ichiro Sekiya, Koji Otabe, Tomomasa Nakamura, Masafumi Horie, Hideyuki Koga, Toshifumi Watanabe, Takeshi Muneta: Acute arterial occlusion after total knee arthroplasty: a case report. Clin Case Rep. 2017.08; 5 (8): 1376-1380. ( PubMed , DOI )

  13. Toshifumi Watanabe, Hideyuki Koga, Masafumi Horie, Hiroki Katagiri, Ichiro Sekiya, Takeshi Muneta: Post-Cam Design and Contact Stress on Tibial Posts in Posterior-Stabilized Total Knee Prostheses: Comparison Between a Rounded and a Squared Design. J Arthroplasty. 2017.07; ( PubMed , DOI )

  14. Eriko Grace Suto, Yo Mabuchi, Nobuharu Suzuki, Koji Suzuki, Yusuke Ogata, Miyu Taguchi, Takeshi Muneta, Ichiro Sekiya, Chihiro Akazawa: Prospectively isolated mesenchymal stem/stromal cells are enriched in the CD73(+) population and exhibit efficacy after transplantation. Sci Rep. 2017.07; 7 (1): 4838. ( PubMed , DOI )

  15. Carballo CB, Nakagawa Y, Sekiya I, Rodeo SA.: Basic Science of Articular Cartilage. Clin Sports Med.. 2017.07; 36 (3): 413-425.

  16. Carballo Camila B., Nakagawa Yusuke, Sekiya Ichiro, Rodeo Scott A.: Basic Science of Articular Cartilage CLINICS IN SPORTS MEDICINE. 2017.07; 36 (3): 413-+. ( PubMed , DOI )

  17. Kunikazu Tsuji, Miyoko Ojima, Koji Otabe, Masafumi Horie, Hideyuki Koga, Ichiro Sekiya, Takeshi Muneta: Effects of Different Cell-Detaching Methods on the Viability and Cell Surface Antigen Expression of Synovial Mesenchymal Stem Cells. Cell Transplant. 2017.06; 26 (6): 1089-1102. ( PubMed , DOI )

  18. Kondo S, Muneta T, Nakagawa Y, Koga H, Watanabe T, Tsuji K, Sotome S, Okawa A, Kiuchi S, Ono H, Mizuno M, Sekiya I.: Transplantation of Autologous Synovial Mesenchymal Stem Cells Promotes Meniscus Regeneration in Aged Primates Journal of Orthopaedic Research. 2017.06; 35 (6): 1274-1282. ( PubMed , DOI )

  19. *Noriko Funato, Masataka Nakamura: Identification of shared and unique gene families associated with oral clefts. Int J Oral Sci. 2017.06; 9 (2): 104-109. ( PubMed , DOI )

  20. Mio Oshikawa, Kei Okada, Naoko Kaneko, Kazunobu Sawamoto, Itsuki Ajioka: Affinity-Immobilization of VEGF on Laminin Porous Sponge Enhances Angiogenesis in the Ischemic Brain. Adv Healthc Mater. 2017.06; 6 (11): ( PubMed , DOI )

  21. Sekiya Ichiro: 動物モデルから臨床応用へ 膝関節の再生医療　疾患モデルから臨床治療へ(From Animal Models to Clinics Regenerative medicine for the knee joint: from disease models to clinical treatments) Experimental Animals. 2017.06; 66 (Suppl.): S15. ( ichushi )

  22. Mitsuru Mizuno, Hisako Katano, Koji Otabe, Keiichiro Komori, Yuji Kohno, Shizuka Fujii, Nobutake Ozeki, Masafumi Horie, Kunikazu Tsuji, Hideyuki Koga, Takeshi Muneta, Ichiro Sekiya: Complete human serum maintains viability and chondrogenic potential of human synovial stem cells: suitable conditions for transplantation. Stem Cell Res Ther. 2017.06; 8 (1): 144. ( PubMed , DOI )

  23. Mitsuru Mizuno, Hisako Katano, Koji Otabe, Keiichiro Komori, Yuji Kohno, Shizuka Fujii, Nobutake Ozeki, Masafumi Horie, Kunikazu Tsuji, Hideyuki Koga, Takeshi Muneta, Ichiro Sekiya: Complete human serum maintains viability and chondrogenic potential of human synovial stem cells: suitable conditions for transplantation. Stem Cell Res Ther. 2017.06; 8 (1): 144. ( PubMed , DOI )

  24. Takao Minami, Takeshi Muneta, Ichiro Sekiya, Toshifumi Watanabe, Tomoyuki Mochizuki, Masafumi Horie, Hiroki Katagiri, Koji Otabe, Toshiyuki Ohara, Mai Katakura, Hideyuki Koga: Lateral meniscus posterior root tear contributes to anterolateral rotational instability and meniscus extrusion in anterior cruciate ligament-injured patients. Knee Surg Sports Traumatol Arthrosc. 2017.05; 26 (4): 1174-1181. ( PubMed , DOI )

  25. Ozeki Nobutake, Muneta Takeshi, Kawabata Kenichi, Koga Hideyuki, Nakagawa Yusuke, Saito Ryusuke, Udo Mio, Yanagisawa Katsuaki, Ohara Toshiyuki, Mochizuki Tomoyuki, Tsuji Kunikazu, Saito Tomoyuki, Sekiya Ichiro: ラットの内側半月板逸脱に対するcentralizationにより軟骨変性が遅延する(Centralization of extruded medial meniscus delays cartilage degeneration in rats) Journal of Orthopaedic Science. 2017.05; 22 (3): 542-548. ( ichushi )

  26. Koga Hideyuki, Watanabe Toshifumi, Horie Masafumi, Katagiri Hiroki, Otabe Koji, Ohara Toshiyuki, Katakura Mai, Sekiya Ichiro, Muneta Takeshi: すべてが分かる半月板損傷の治療 半月板突出の関節鏡下centralization法と膝関節症における膝関節機能回復のための本手術法の応用(Arthroscopic Centralization of an Extruded Meniscus and Its Application to Knee Osteoarthritis to Restore Knee Function) JOSKAS. 2017.05; 42 (4): 526. ( ichushi )

  27. Nobutake Ozeki, Takeshi Muneta, Kenichi Kawabata, Hideyuki Koga, Yusuke Nakagawa, Ryusuke Saito, Mio Udo, Katsuaki Yanagisawa, Toshiyuki Ohara, Tomoyuki Mochizuki, Kunikazu Tsuji, Tomoyuki Saito, Ichiro Sekiya: Centralization of extruded medial meniscus delays cartilage degeneration in rats. J Orthop Sci. 2017.05; 22 (3): 542-548. ( PubMed , DOI )

  28. Yuji Kohno, Mitsuru Mizuno, Nobutake Ozeki, Hisako Katano, Keiichiro Komori, Shizuka Fujii, Koji Otabe, Masafumi Horie, Hideyuki Koga, Kunikazu Tsuji, Mikio Matsumoto, Haruka Kaneko, Yuji Takazawa, Takeshi Muneta, Ichiro Sekiya: Yields and chondrogenic potential of primary synovial mesenchymal stem cells are comparable between rheumatoid arthritis and osteoarthritis patients. Stem Cell Res Ther. 2017.05; 8 (1): 115. ( PubMed , DOI )

  29. Yuji Kohno, Mitsuru Mizuno, Nobutake Ozeki, Hisako Katano, Keiichiro Komori, Shizuka Fujii, Koji Otabe, Masafumi Horie, Hideyuki Koga, Kunikazu Tsuji, Mikio Matsumoto, Haruka Kaneko, Yuji Takazawa, Takeshi Muneta, Ichiro Sekiya: Yields and chondrogenic potential of primary synovial mesenchymal stem cells are comparable between rheumatoid arthritis and osteoarthritis patients. Stem Cell Res Ther. 2017.05; 8 (1): 115. ( PubMed , DOI )

  30. Mikio Shioda, Takeshi Muneta, Kunikazu Tsuji, Mitsuru Mizuno, Keiichiro Komori, Hideyuki Koga, Ichiro Sekiya: TNFα promotes proliferation of human synovial MSCs while maintaining chondrogenic potential. PLoS ONE. 2017.05; 12 (5): e0177771. ( PubMed , DOI )

  31. Mikio Shioda, Takeshi Muneta, Kunikazu Tsuji, Mitsuru Mizuno, Keiichiro Komori, Hideyuki Koga, Ichiro Sekiya: TNFα promotes proliferation of human synovial MSCs while maintaining chondrogenic potential. PLoS ONE. 2017.05; 12 (5): e0177771. ( PubMed , DOI )

  32. Jae-Sung An, Takeshi Muneta, Ichiro Sekiya, Toshifumi Watanabe, Tomoyuki Mochizuki, Masafumi Horie, Tomomasa Nakamura, Koji Otabe, Hideyuki Koga: Osteochondral lesion of lateral tibial plateau with extrusion of lateral meniscus treated with retrograde osteochondral autograft transplantation and arthroscopic centralisation. AP-SMART. 2017.04; 8 18-23. ( DOI )

  33. Katagiri Kenta, Yu Matsukura, Takeshi Muneta, Nobutake Ozeki, Mitsuru Mizuno, Hisako Katano, Ichiro Sekiya.: Fibrous synovium releases higher numbers of mesenchymal stem cells than adipose synovium in a suspended synovium culture model. Arthroscopy. 2017.04; 33 (4): 800-810. ( PubMed )

  34. Katagiri Kenta, Yu Matsukura, Takeshi Muneta, Nobutake Ozeki, Mitsuru Mizuno, Hisako Katano, Ichiro Sekiya.: Fibrous synovium releases higher numbers of mesenchymal stem cells than adipose synovium in a suspended synovium culture model. Arthroscopy. 2017.04; 33 (4): 800-810. ( PubMed )

  35. Ojima M., Tsuji K., Otabe K., Horie M., Koga H., Sekiya I., Muneta T.: ANALYSES OF BIOLOGICALLY ACTIVE SUBSTANCES IN SYNOVIAL FLUID WHICH SUPPORT PROLIFERATION OF SYNOVIAL MESENCHYMAL STEM CELLS OSTEOARTHRITIS AND CARTILAGE. 2017.04; 25 S425-S426.

  36. Katagiri Kenta, Yu Matsukura, Takeshi Muneta, Nobutake Ozeki, Mitsuru Mizuno, Hisako Katano, Ichiro Sekiya.: Fibrous synovium releases higher numbers of mesenchymal stem cells than adipose synovium in a suspended synovium culture model. Arthroscopy. 2017.04; 33 (4): 800-810. ( PubMed , DOI )

  37. Hsing-Yi Lin, Naoki Fujita, Kentaro Endo, Maresuke Morita, Tae Takeda, Takayuki Nakagawa, Ryohei Nishimura: Isolation and Characterization of Multipotent Mesenchymal Stem Cells Adhering to Adipocytes in Canine Bone Marrow. Stem Cells Dev. 2017.03; 26 (6): 431-440. ( PubMed , DOI )

  38. Watanabe Toshifumi, Muneta Takeshi, Koga Hideyuki, Horie Masafumi, Otabe Koji, Ohara Toshiyuki, Nakamura Kaori, Katakura Mai, Okawa Atsushi, Sekiya Ichiro: 人工膝関節全置換術における脛骨ポストに対するカム後部設計と接触ストレス　円形と角型デザインの比較(Post-cam design and contact stress on tibial posts in total knee prostheses: Comparison between a rounded and a squared design) 日本整形外科学会雑誌. 2017.03; 91 (2): S453. ( ichushi )

  39. Yuuki Arata, Muneta Takeshi, Ohara Toshiyuki, Sekiya Ichiro, Koga Hideyuki: 前十字靱帯損傷膝における外側/内側膝不安定性とその関連要因との相関(Associated lateral/medial knee instability and its relevant factors in anterior cruciate ligament-injured knees) Journal of Orthopaedic Science. 2017.03; 22 (2): 300-305. ( ichushi )

  40. Matsumura E, Tsuji K, Komori K, Koga H, Sekiya I, Muneta T.: Pretreatment of IL-1β enhances proliferation and chondrogenic potential of synovium-derived mesenchymal stem cells. Cytotherapy. 2017.02; 19 (2): 181-193. ( PubMed , DOI )

  41. Teppei Fujioka, Naoko Kaneko, Itsuki Ajioka, Kanako Nakaguchi, Taichi Omata, Honoka Ohba, Reinhard Fässler, José Manuel García-Verdugo, Kiyotoshi Sekiguchi, Noriyuki Matsukawa, Kazunobu Sawamoto: β1 integrin signaling promotes neuronal migration along vascular scaffolds in the post-stroke brain. EBioMedicine. 2017.02; 16 195-203. ( PubMed , DOI )

  42. Akihisa Hatakeyama, Soshi Uchida, Hajime Utsunomiya, Manabu Tsukamoto, Hirotaka Nakashima, Eiichiro Nakamura, Cecilia Pascual-Garrido, Ichiro Sekiya, Akinori Sakai: Isolation and Characterization of Synovial Mesenchymal Stem Cell Derived from Hip Joints: A Comparative Analysis with a Matched Control Knee Group. Stem Cells Int. 2017.01; 2017 9312329. ( PubMed , DOI )

  43. Saito R, Muneta T, Ozeki N, Nakagawa Y, Udo M, Yanagisawa K, Tsuji K, Tomita M, Koga H, Sekiya I.: Strenuous running exacerbates knee cartilage erosion induced by low amount of mono-iodoacetate in rats. BMC Musculoskelet Disord. 2017.01; 18 (1): 36.

  44. Saito R, Muneta T, Ozeki N, Nakagawa Y, Udo M, Yanagisawa K, Tsuji K, Tomita M, Koga H, Sekiya I.: Strenuous running exacerbates knee cartilage erosion induced by low amount of mono-iodoacetate in rats. BMC Musculoskelet Disord. 2017.01; 18 (1): 36. ( PubMed , DOI )

  1. Inoue M, Muneta T, Ojima M, Nakamura K, Koga H, Sekiya I, Okazaki M, Tsuji K.: Inflammatory cytokine levels in synovial fluid 3, 4 days postoperatively and its correlation with early-phase functional recovery after anterior cruciate ligament reconstruction: a cohort study. J Exp Orthop.. 2016.12; 3 (1): 30. ( PubMed )

  2. Toshiyuki Ohara, Takeshi Muneta, Yusuke Nakagawa, Yu Matsukura, Shizuko Ichinose, Hideyuki Koga, Kunikazu Tsuji, Ichiro Sekiya: Hypoxia enhances proliferation through increase of colony formation rate with chondrogenic potential in primary synovial mesenchymal stem cells. J. Med. Dent. Sci.. 2016.12; 63 (4): 61-70. ( PubMed , DOI )

  3. Kaori Nakamura, Hideyuki Koga, Ichiro Sekiya, Toshifumi Watanabe, Tomoyuki Mochizuki, Masafumi Horie, Tomomasa Nakamura, Koji Otabe, Takeshi Muneta: Dynamic Evaluation of Pivot-Shift Phenomenon in Double-Bundle Anterior Cruciate Ligament Reconstruction Using Triaxial Accelerometer. Arthroscopy. 2016.12; 32 (12): 2532-2538. ( PubMed , DOI )

  4. Shirasawa S, Koga H, Horie M, Nakamura T, Watanabe T, Sekiya I, Muneta T.: Forced knee extension test is a manual test that correlates with the unstable feelings of patients with ACL injury before and after reconstruction. Knee. 2016.12; 23 (6): 1159-1163. ( PubMed )

  5. Kanehiro Hiyama, Takeshi Muneta, Hideyuki Koga, Ichiro Sekiya, Kunikazu Tsuji: Meniscal regeneration after resection of the anterior half of the medial meniscus in mice. J. Orthop. Res.. 2016.11; ( PubMed , DOI )

  6. Watanabe T, Muneta T, Koga H, Horie M, Nakamura T, Otabe K, Nakagawa Y, Katakura M, Sekiya I.: In-vivo kinematics of high-flex posterior-stabilized total knee prosthesis designed for Asian populations. Int Orthop. 2016.11; 40 (11): 2295-2302. ( PubMed , DOI )

  7. Arata Yuuki, Takeshi Muneta, Toshiyuki Ohara, Ichiro Sekiya, Hideyuki Koga: Associated lateral/medial knee instability and its relevant factors in anterior cruciate ligament-injured knees. J Orthop Sci. 2016.11; ( PubMed , DOI )

  8. Nobutaka Ishizu, Daishi Yui, Akira Hebisawa, Hidenori Aizawa, Wanpeng Cui, Yuko Fujita, Kenji Hashimoto, Itsuki Ajioka, Hidehiro Mizusawa, Takanori Yokota, Kei Watase: Impaired striatal dopamine release in homozygous Vps35 D620N knock-in mice. Hum. Mol. Genet.. 2016.10; 25 (20): 4507-4517. ( PubMed , DOI )

  9. Hitoshi Suzuki, Yoshitsugu Aoki, Toshiki Kameyama, Takashi Saito, Satoru Masuda, Jun Tanihata, Tetsuya Nagata, Akila Mayeda, Shin'ichi Takeda, Toshifumi Tsukahara: Endogenous Multiple Exon Skipping and Back-Splicing at the DMD Mutation Hotspot. Int J Mol Sci. 2016.10; 17 (10): ( PubMed , DOI )

  10. Koga H, Muneta T, Watanabe T, Mochizuki T, Horie M, Nakamura T, Otabe K, Nakagawa Y, Sekiya I.: Two-Year Outcomes After Arthroscopic Lateral Meniscus Centralization Arthroscopy. 2016.10; 32 (10): 2000-2008.

  11. Takeshi Muneta, Hideyuki Koga, Tomomasa Nakamura, Masafumi Horie, Toshifumi Watanabe, Ichiro Sekiya: Behind-remnant arthroscopic observation and scoring of femoral attachment of injured anterior cruciate ligament. Knee Surg Sports Traumatol Arthrosc. 2016.09; 24 (9): 2906-2914. ( PubMed , DOI )

  12. Hiroki Katagiri, Kaori Nakamura, Toshifumi Watanabe, Hideyuki Koga, Kazuyoshi Yagishita, Ichiro Sekiya, Takeshi Muneta: Increase of patellofemoral height has decreased maximum knee flexion after total knee arthroplasty of posterior cruciate-substituting prosthesis in a clinical series. J Orthop Sci. 2016.07; 21 (4): 458-462. ( PubMed , DOI )

  13. Mio Udo, Takeshi Muneta, Kunikazu Tsuji, Nobutake Ozeki, Yusuke Nakagawa, Toshiyuki Ohara, Ryusuke Saito, Katsuaki Yanagisawa, Hideyuki Koga, Ichiro Sekiya: Monoiodoacetic acid induces arthritis and synovitis in rats in a dose- and time-dependent manner: proposed model-specific scoring systems. Osteoarthr. Cartil.. 2016.07; 24 (7): 1284-1291. ( PubMed , DOI )

  14. N Ozeki, T Muneta, H Koga, Y Nakagawa, M Mizuno, K Tsuji, Y Mabuchi, C Akazawa, E Kobayashi, K Matsumoto, K Futamura, T Saito, I Sekiya: Not single but periodic injections of synovial mesenchymal stem cells maintain viable cells in knees and inhibit osteoarthritis progression in rats. Osteoarthr. Cartil.. 2016.06; 24 (6): 1061-1070. ( PubMed , DOI )

  15. *Noriko Funato, Hiroki Kokubo, Yumiko Saga: Transcriptomic analyses of Hand2 transgenic embryos. Genom Data. 2016.06; 9 60-62. ( PubMed , DOI )

  16. *Noriko Funato, Hiroki Kokubo, Masataka Nakamura, Hiromi Yanagisawa, Yumiko Saga: Specification of jaw identity by the Hand2 transcription factor. Sci Rep. 2016.06; 6 28405. ( PubMed , DOI )

  17. Kazumasa Miyatake, Takeshi Muneta, Miyoko Ojima, Jun Yamada, Yu Matsukura, Kahaer Abula, Ichiro Sekiya, Kunikazu Tsuji: Coordinate and synergistic effects of extensive treadmill exercise and ovariectomy on articular cartilage degeneration. BMC Musculoskelet Disord. 2016.05; 17 (1): 238. ( PubMed , DOI )

  18. Mai Katakura, Hideyuki Koga, Kaori Nakamura, Ichiro Sekiya, Takeshi Muneta: Effects of different femoral tunnel positions on tension changes in anterolateral ligament reconstruction. Knee Surg Sports Traumatol Arthrosc. 2016.05; 25 (4): 1272-1278. ( PubMed , DOI )

  19. Mutsuki Kuraoka, En Kimura, Tetsuya Nagata, Takashi Okada, Yoshitsugu Aoki, Hisateru Tachimori, Naohiro Yonemoto, Michihiro Imamura, Shin'ichi Takeda: Serum Osteopontin as a Novel Biomarker for Muscle Regeneration in Duchenne Muscular Dystrophy. Am. J. Pathol.. 2016.05; 186 (5): 1302-1312. ( PubMed , DOI )

  20. Koichi Kimura, Hiroyuki Morita, Masao Daimon, Masaru Horio, Takayuki Kawata, Tomoko Nakao, Megumi Hirokawa, Ruriko Kitao, Daisuke Watanabe, Tetsuo Komori, Tetsuya Nagata, Shin'ichi Takeda, Hirofumi Komaki, Kazuhiko Segawa, Takashi Nakajima, Katsu Takenaka, Issei Komuro: Utility of Cystatin C for Estimating Glomerular Filtration Rate in Patients With Muscular Dystrophy. Int Heart J. 2016.05; 57 (3): 386-388. ( PubMed , DOI )

  21. Katsuaki Yanagisawa, Takeshi Muneta, Nobutake Ozeki, Yusuke Nakagawa, Mio Udo, Ryusuke Saito, Hideyuki Koga, Kunikazu Tsuji, Ichiro Sekiya: Weekly injections of Hylan G-F 20 delay cartilage degeneration in partial meniscectomized rat knees. BMC Musculoskelet Disord. 2016.04; 17 (1): 188. ( PubMed , DOI )

  22. Toshifumi Watanabe, Takeshi Muneta, Kazuyoshi Yagishita, Kenji Hara, Hideyuki Koga, Ichiro Sekiya: Closed Suction Drainage Is Not Necessary for Total Knee Arthroplasty: A Prospective Study on Simultaneous Bilateral Surgeries of a Mean Follow-Up of 5.5 Years. J Arthroplasty. 2016.03; 31 (3): 641-645. ( PubMed , DOI )

  23. Yusuke Nakagawa, Takeshi Muneta, Koji Otabe, Nobutake Ozeki, Mitsuru Mizuno, Mio Udo, Ryusuke Saito, Katsuaki Yanagisawa, Shizuko Ichinose, Hideyuki Koga, Kunikazu Tsuji, Ichiro Sekiya: Cartilage Derived from Bone Marrow Mesenchymal Stem Cells Expresses Lubricin In Vitro and In Vivo. PLoS ONE. 2016.02; 11 (2): e0148777. ( PubMed , DOI )

  24. Chisato Sato, Yoshitaka Iso, Takuya Mizukami, Koji Otabe, Masahiro Sasai, Masaaki Kurata, Takeyuki Sanbe, Ichiro Sekiya, Akira Miyazaki, Hiroshi Suzuki: Fibroblast growth factor-23 induces cellular senescence in human mesenchymal stem cells from skeletal muscle. Biochem. Biophys. Res. Commun.. 2016.02; 470 (3): 657-662. ( PubMed , DOI )

  25. Shimpei Kondo, Takeshi Muneta, Yusuke Nakagawa, Hideyuki Koga, Toshifumi Watanabe, Kunikazu Tsuji, Shinichi Sotome, Atsushi Okawa, Shinji Kiuchi, Hideo Ono, Mitsuru Mizuno, Ichiro Sekiya: Transplantation of autologous synovial mesenchymal stem cells promotes meniscus regeneration in aged primates. J. Orthop. Res.. 2016.02; 35 (6): 1274-1282. ( PubMed , DOI )

  26. Lindsay E Laurie, Hiroki Kokubo, Masataka Nakamura, Yumiko Saga, *Noriko Funato: The transcription factor Hand1 is involved in Runx2-Ihh-regulated endochondral ossification PLoS ONE. 2016.02; 11 (2): e0150263. ( PubMed , DOI )

  27. Yusuke Nakagawa, Ichiro Sekiya, Shimpei Kondo, Takashi Tabuchi, Shizuko Ichinose, Hideyuki Koga, Kunikazu Tsuji, Takeshi Muneta: Relationship between MRI T1 rho value and histological findings of intact and radially incised menisci in microminipigs. J Magn Reson Imaging. 2016.02; 43 (2): 434-445. ( PubMed , DOI )

  28. Mariko Mizuguchi, Yuka Sasaki, Toshifumi Hara, Masaya Higuchi, Yuetsu Tanaka, Noriko Funato, Nobuyuki Tanaka, Masahiro Fujii, Masataka Nakamura: Induction of Cell Death in Growing Human T-Cells and Cell Survival in Resting Cells in Response to the Human T-Cell Leukemia Virus Type 1 Tax. PLoS ONE. 2016.02; 11 (2): e0148217. ( PubMed , DOI )

  1. Mitsuru Mizuno, Hisako Katano, Koji Otabe, Keiichiro Komori, Yukie Matsumoto, Shizuka Fujii, Nobutake Ozeki, Kunikazu Tsuji, Hideyuki Koga, Takeshi Muneta, Akifumi Matsuyama, Ichiro Sekiya: Platelet-derived growth factor (PDGF)-AA/AB in human serum are potential indicators of the proliferative capacity of human synovial mesenchymal stem cells. Stem Cell Res Ther. 2015.12; 6 (1): 243. ( PubMed , DOI )

  2. Muneta T, Koga H, Nakamura T, Horie M, Watanabe T, Yagishita K, Sekiya I: A new behind-remnant approach for remnant-preserving double-bundle anterior cruciate ligament reconstruction compared with a standard approach Knee Surg Sports Traumatol Arthrosc. 2015.12; 23 (12): 3743-3749.

  3. Toshifumi Watanabe, Takeshi Muneta, Ichiro Sekiya, Scott A Banks: Intraoperative joint gaps and mediolateral balance affect postoperative knee kinematics in posterior-stabilized total knee arthroplasty. Knee. 2015.12; 22 (6): 527-534. ( PubMed , DOI )

  4. Noriko Funato, Masataka Nakamura, Hiromi Yanagisawa: Molecular basis of cleft palates in mice. World J Biol Chem. 2015.08; 6 (3): 121-138. ( PubMed , DOI )

  5. Kivanc Atesok, Freddie H Fu, Ichiro Sekiya, Alexandra Stolzing, Mitsuo Ochi, Scott A Rodeo: Stem cells in degenerative orthopaedic pathologies: effects of aging on therapeutic potential. Knee Surg Sports Traumatol Arthrosc. 2015.08; 25 (2): 626-636. ( PubMed , DOI )

  6. Ichiro Sekiya, Takeshi Muneta, Masafumi Horie, Hideyuki Koga: Arthroscopic Transplantation of Synovial Stem Cells Improves Clinical Outcomes in Knees With Cartilage Defects. Clin. Orthop. Relat. Res.. 2015.07; 473 (7): 2316-2326. ( PubMed , DOI )

  7. Hideyuki Koga, Takeshi Muneta, Kazuyoshi Yagishita, Toshifumi Watanabe, Tomoyuki Mochizuki, Masafumi Horie, Tomomasa Nakamura, Koji Otabe, Ichiro Sekiya: Evaluation of a behind-remnant approach for femoral tunnel creation in remnant-preserving double-bundle anterior cruciate ligament reconstruction - Comparison with a standard approach. Knee. 2015.06; 22 (3): 249-255. ( PubMed , DOI )

  8. Yusuke Ogata, Yo Mabuchi, Mayu Yoshida, Eriko Grace Suto, Nobuharu Suzuki, Takeshi Muneta, Ichiro Sekiya, Chihiro Akazawa: Purified Human Synovium Mesenchymal Stem Cells as a Good Resource for Cartilage Regeneration. PLoS ONE. 2015.06; 10 (6): e0129096. ( PubMed , DOI )

  9. Nobutake Ozeki, Takeshi Muneta, Seiya Matsuta, Hideyuki Koga, Yusuke Nakagawa, Mitsuru Mizuno, Kunikazu Tsuji, Yo Mabuchi, Chihiro Akazawa, Eiji Kobayashi, Tomoyuki Saito, Ichiro Sekiya: Synovial mesenchymal stem cells promote meniscus regeneration augmented by an autologous Achilles tendon graft in a rat partial meniscus defect model. Stem Cells. 2015.06; 33 (6): 1927-1938. ( PubMed , DOI )

  10. Yusuke Nakagawa, Takeshi Muneta, Shimpei Kondo, Mitsuru Mizuno, Kazuo Takakuda, Shizuko Ichinose, Takashi Tabuchi, Hideyuki Koga, Kunikazu Tsuji, Ichiro Sekiya: Synovial mesenchymal stem cells promote healing after meniscal repair in microminipigs. Osteoarthr. Cartil.. 2015.05; 589 (11): 1240-1248. ( PubMed , DOI )

  11. Hideyuki Koga, Takeshi Muneta, Kazuyoshi Yagishita, Toshifumi Watanabe, Tomoyuki Mochizuki, Masafumi Horie, Tomomasa Nakamura, Koji Otabe, Ichiro Sekiya: Effect of Posterolateral Bundle Graft Fixation Angles on Clinical Outcomes in Double-Bundle Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial. Am J Sports Med. 2015.05; 43 (5): 1157-1164. ( PubMed , DOI )

  12. Kahaer Abula, Takeshi Muneta, Kazumasa Miyatake, Jun Yamada, Yu Matsukura, Makiko Inoue, Ichiro Sekiya, Daniel Graf, Aris N Economides, Vicki Rosen, Kunikazu Tsuji: Elimination of BMP7 from the developing limb mesenchyme leads to articular cartilage degeneration and synovial inflammation with increased age. FEBS Lett.. 2015.05; 589 (11): 1240-1248. ( PubMed , DOI )

  13. Hideyuki Koga, Takeshi Muneta, Kazuyoshi Yagishita, Toshifumi Watanabe, Tomoyuki Mochizuki, Masafumi Horie, Tomomasa Nakamura, Koji Otabe, Ichiro Sekiya: Effect of Initial Graft Tension on Knee Stability and Graft Tension Pattern in Double-Bundle Anterior Cruciate Ligament Reconstruction. Arthroscopy. 2015.04; ( PubMed , DOI )

  14. Masaki Y, Inde T, Nagata T, Tanihata J, Kanamori T, Seio K, Takeda S, Sekine M: Enhancement of exon skipping in mdx52 mice by 2'-O-methyl-2-thioribothymidine incorporation into phosphorothioate oligonucleotides Med Chem Commun. 2015.04; 6 630-633. ( DOI )

  15. Suto EG, Mabuchi Y, Suzuki N, Koyanagi A, Kawabata Y, Ogata Y, Ozeki N, Nakagawa Y, Muneta T, Sekiya I, Akazawa C: High capacity of puri ed mesenchymal stem cells for cartilage regeneration  Inflammation and Regeneration. 2015.03; 35 (2): 78-85. ( DOI )

  16. Yu Matsukura, Takeshi Muneta, Kunikazu Tsuji, Kazumasa Miyatake, Jun Yamada, Kahaer Abula, Hideyuki Koga, Makoto Tomita, Ichiro Sekiya: Mouse synovial mesenchymal stem cells increase in yield with knee inflammation. J. Orthop. Res.. 2015.02; 33 (2): 246-253. ( PubMed , DOI )

  17. Noriko Funato, Masataka Nakamura, James A. Richardson, Deepack Srivastava, Hiromi Yanagisawa.: Loss of Tbx1 induces bone phenotypes similar to cleidocranial dysplasia. Hum Mol Genet. 2015.01; 24 (2): 424-435. ( PubMed , DOI )

  18. Koji Otabe, Hiroyuki Nakahara, Akihiko Hasegawa, Tetsuya Matsukawa, Fumiaki Ayabe, Naoko Onizuka, Masafumi Inui, Shuji Takada, Yoshiaki Ito, Ichiro Sekiya, Takeshi Muneta, Martin Lotz, Hiroshi Asahara: Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo. J. Orthop. Res.. 2015.01; 33 (1): 1-8. ( PubMed , DOI )

  1. Hideyuki Koga, Takeshi Muneta, Kazuyoshi Yagishita, Toshifumi Watanabe, Tomoyuki Mochizuki, Masafumi Horie, Tomomasa Nakamura, Ichiro Sekiya: Effect of femoral tunnel position on graft tension curves and knee stability in anatomic double-bundle anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc. 2014.11; 22 (11): 2811-2820. ( PubMed , DOI )

  2. Nobukatsu Horita, Kiichiro Tsuchiya, Ryohei Hayashi, Keita Fukushima, Shuji Hibiya, Masayoshi Fukuda, Yoshihito Kano, Tomohiro Mizutani, Yasuhiro Nemoto, Shiro Yui, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe: Fluorescent labelling of intestinal epithelial cells reveals independent long-lived intestinal stem cells in a crypt. Biochem. Biophys. Res. Commun. 2014.10; 454 (4): 493-499. ( PubMed , DOI )

  3. Hideyuki Koga, Takeshi Muneta, Kazuyoshi Yagishita, Toshifumi Watanabe, Tomoyuki Mochizuki, Masafumi Horie, Tomomasa Nakamura, Koji Otabe, Ichiro Sekiya: Mid- to Long-term Results of Single-Bundle Versus Double-Bundle Anterior Cruciate Ligament Reconstruction: Randomized Controlled Trial. Arthroscopy. 2014.09; ( PubMed , DOI )

  4. Takeshi Muneta, Hideyuki Koga, Tomomasa Nakamura, Masafumi Horie, Toshifumi Watanabe, Kazuyoshi Yagishita, Ichiro Sekiya: A new behind-remnant approach for remnant-preserving double-bundle anterior cruciate ligament reconstruction compared with a standard approach. Knee Surg Sports Traumatol Arthrosc. 2014.09; ( PubMed , DOI )

  5. Itsuki Ajioka, Hideo Jinnou, Kei Okada, Masato Sawada, Shinji Saitoh, Kazunobu Sawamoto: Enhancement of Neuroblast Migration into the Injured Cerebral Cortex Using Laminin-Containing Porous Sponge. Tissue Eng Part A. 2014.08; ( PubMed , DOI )

  6. Nobuharu Suzuki, Chihiro Mizuniwa, Kana Ishii, Yusuke Nakagawa, Kunikazu Tsuji, Takeshi Muneta, Ichiro Sekiya, Chihiro Akazawa: Teneurin-4, a transmembrane protein, is a novel regulator that suppresses chondrogenic differentiation. J. Orthop. Res.. 2014.07; 32 (7): 915-922. ( PubMed , DOI )

  7. Makiko Okuno, Takeshi Muneta, Hideyuki Koga, Nobutake Ozeki, Yusuke Nakagawa, Kunikazu Tsuji, Shinichi Yoshiya, Ichiro Sekiya: Meniscus regeneration by syngeneic, minor mismatched, and major mismatched transplantation of synovial mesenchymal stem cells in a rat model. J. Orthop. Res.. 2014.07; 32 (7): 928-936. ( PubMed , DOI )

  8. D Hatsushika, T Muneta, T Nakamura, M Horie, H Koga, Y Nakagawa, K Tsuji, S Hishikawa, E Kobayashi, I Sekiya: Repetitive allogeneic intraarticular injections of synovial mesenchymal stem cells promote meniscus regeneration in a porcine massive meniscus defect model. Osteoarthr. Cartil.. 2014.07; 22 (7): 941-950. ( PubMed , DOI )

  9. Itsuki Ajioka: Coordination of proliferation and neuronal differentiation by the retinoblastoma protein family. Dev. Growth Differ.. 2014.06; 56 (5): 324-334. ( PubMed , DOI )

  10. Hideyuki Koga, Takeshi Muneta, Kazuyoshi Yagishita, Toshifumi Watanabe, Tomoyuki Mochizuki, Masafumi Horie, Tomomasa Nakamura, Ichiro Sekiya: Effect of Notchplasty in Anatomic Double-Bundle Anterior Cruciate Ligament Reconstruction. Am J Sports Med. 2014.06; 42 (8): 1813-1821. ( PubMed , DOI )

  11. Ichiro Sekiya, Seth S Leopold: Editor's spotlight/Take 5: Mesenchymal stem cells in synovial fluid increase after meniscus injury. Clin. Orthop. Relat. Res.. 2014.05; 472 (5): 1353-1356. ( PubMed , DOI )

  12. Yu Matsukura, Takeshi Muneta, Kunikazu Tsuji, Hideyuki Koga, Ichiro Sekiya: Mesenchymal stem cells in synovial fluid increase after meniscus injury. Clin. Orthop. Relat. Res.. 2014.05; 472 (5): 1357-1364. ( PubMed , DOI )

  13. Morita J, Nakamura M, Kobayashi Y, Deng C, Funato N, Moriyama K: Soluble form of FGFR2 with S252W partially prevents craniosynostosis of the apert mouse model. Dev. Dyn.. 2014.04; 243 (4): 560-567. ( PubMed , DOI )

  14. Tatsuro Murano, Ryuichi Okamoto, Go Ito, Toru Nakata, Shuji Hibiya, Hiromichi Shimizu, Satoru Fujii, Yoshihito Kano, Tomohiro Mizutani, Shiro Yui, Junko Akiyama-Morio, Yasuhiro Nemoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe: Hes1 promotes the IL-22-mediated antimicrobial response by enhancing STAT3-dependent transcription in human intestinal epithelial cells. Biochem. Biophys. Res. Commun. 2014.01; 443 (3): 840-846. ( PubMed , DOI )

  15. Yamada Jun, Tsuji Kunikazu, Miyatake Kazumasa, Matsukura Yu, Abula Kahaer, Inoue Makiko, Sekiya Ichiro, Muneta Takeshi: Follistatin alleviates synovitis and articular cartilage degeneration induced by carrageenan. Int J Inflam. 2014; 2014 959271. ( PubMed , DOI )

  16. Hirofumi Fujita, Hanako Aoki, Itsuki Ajioka, Maya Yamazaki, Manabu Abe, Arata Oh-Nishi, Kenji Sakimura, Izumi Sugihara: Detailed expression pattern of aldolase C (Aldoc) in the cerebellum, retina and other areas of the CNS studied in Aldoc-Venus knock-in mice. PLoS ONE. 2014; 9 (1): e86679. ( PubMed , DOI )

  1. Tomomasa Nakamura, Ichiro Sekiya, Takeshi Muneta, Eiji Kobayashi: [Articular cartilage regenerative therapy with synovial mesenchymal stem cells in a pig model]. Clin Calcium. 2013.12; 23 (12): 1741-1749. ( PubMed , DOI )

  2. Robert P Fordham, Shiro Yui, Nicholas R F Hannan, Christoffer Soendergaard, Alison Madgwick, Pawel J Schweiger, Ole H Nielsen, Ludovic Vallier, Roger A Pedersen, Tetsuya Nakamura, Mamoru Watanabe, Kim B Jensen: Transplantation of expanded fetal intestinal progenitors contributes to colon regeneration after injury. Cell Stem Cell. 2013.12; 13 (6): 734-744. ( PubMed , DOI )

  3. Ozeki Nobutake, Muneta Takeshi, Koga Hideyuki, Katagiri Hiroki, Otabe Koji, Okuno Makiko, Tsuji Kunikazu, Kobayashi Eiji, Matsumoto Kenji, Saito Hirohisa, Saito Tomoyuki, Sekiya Ichiro: Transplantation of Achilles tendon treated with bone morphogenetic protein 7 promotes meniscus regeneration in a rat model of massive meniscal defect. Arthritis Rheum. 2013.11; 65 (11): 2876-2886. ( PubMed , DOI )

  4. Go Ito, Ryuichi Okamoto, Tatsuro Murano, Hiromichi Shimizu, Satoru Fujii, Toru Nakata, Tomohiro Mizutani, Shiro Yui, Junko Akiyama-Morio, Yasuhiro Nemoto, Eriko Okada, Akihiro Araki, Kazuo Ohtsuka, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe: Lineage-specific expression of bestrophin-2 and bestrophin-4 in human intestinal epithelial cells. PLoS ONE. 2013.11; 8 (11): e79693. ( PubMed , DOI )

  5. Terumi Mizukoshi, Hideyuki Komori, Mariko Mizuguchi, Hussein Abdelaziz, Toshifumi Hara, Masaya Higuchi, Yuetsu Tanaka, Yoshiro Ohara, Noriko Funato, Masahiro Fujii, Masataka Nakamura: Failure in activation of the canonical NF-κB pathway by human T-cell leukemia virus type 1 Tax in non-hematopoietic cell lines. Virology. 2013.09; 443 (2): 226-235. ( PubMed , DOI )

  6. Hiroki Katagiri, Takeshi Muneta, Kunikazu Tsuji, Masafumi Horie, Hideyuki Koga, Nobutake Ozeki, Eiji Kobayashi, Ichiro Sekiya: Transplantation of aggregates of synovial mesenchymal stem cells regenerates meniscus more effectively in a rat massive meniscal defect. Biochem. Biophys. Res. Commun.. 2013.06; 435 (4): 603-609. ( PubMed , DOI )

  7. Mio Oshikawa, Kei Okada, Kazunori Nakajima, Itsuki Ajioka: Cortical excitatory neurons become protected from cell division during neurogenesis in an Rb family-dependent manner. Development. 2013.06; 140 (11): 2310-2320. ( PubMed , DOI )

  1. Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H: Tbx1 regulates oral epithelial adhesion and palatal development. Hum Mol Genet. 2012.03; 21 (11): 2524-2537. ( PubMed , DOI )

  2. Tomohiro Mizutani, Tetsuya Nakamura, Ryo Morikawa, Masayoshi Fukuda, Wakana Mochizuki, Yuhki Yamauchi, Kengo Nozaki, Shiro Yui, Yasuhiro Nemoto, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Mamoru Watanabe: Real-time analysis of P-glycoprotein-mediated drug transport across primary intestinal epithelium three-dimensionally cultured in vitro. Biochem. Biophys. Res. Commun.. 2012.03; 419 (2): 238-243. ( PubMed , DOI )

  3. Shiro Yui, Tetsuya Nakamura, Toshiro Sato, Yasuhiro Nemoto, Tomohiro Mizutani, Xiu Zheng, Shizuko Ichinose, Takashi Nagaishi, Ryuichi Okamoto, Kiichiro Tsuchiya, Hans Clevers, Mamoru Watanabe: Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5⁺ stem cell. Nat. Med.. 2012.03; 18 (4): 618-623. ( PubMed , DOI )

  4. Koga Hideyuki, Muneta Takeshi, Yagishita Kazuyoshi, Ju Young-Jin, Sekiya Ichiro: Surgical management of grade 3 medial knee injuries combined with cruciate ligament injuries. Knee Surg Sports Traumatol Arthrosc. 2012.01; 20 (1): 88-94. ( PubMed , DOI )

  5. Koga H, Muneta T, Yagishita K, Ju YJ, Sekiya I: The Effect of Graft Fixation Angles on Anteroposterior and Rotational Knee Laxity in Double-Bundle Anterior Cruciate Ligament Reconstruction: Evaluation Using Computerized Navigation Am J Sports Med. 2012;

  6. Nakamura T, Sekiya I, Muneta T, Hatsushika D, Horie M, Tsuji K, Kawarasaki T, Watanabe A, Hishikawa S, Fujimoto Y, Tanaka H, Kobayashi E: Arthroscopic, histological, and MRI analyses of cartilage repair after a minimally invasive method of transplantation of allogeneic synovial mesenchymal stem cells into cartilage defects in pigs Cytotherapy. 2012;

  1. Itsuki Ajioka, Shizuko Ichinose, Kazunori Nakajima, Hidehiro Mizusawa: Basement membrane-like matrix sponge for the three-dimensional proliferation culture of differentiated retinal horizontal interneurons. Biomaterials. 2011.09; 32 (25): 5765-5772. ( PubMed , DOI )

  1. Aoki Y, Nakamura A, Yokota T, Saito T, Okazawa H, Nagata T, Takeda SI: In-frame dystrophin following exon 51-skipping improves muscle pathology and function in the exon 52-deficient mdx mouse. Mol Ther. 2010.11; 18 (11): 1995-2005. ( PubMed , DOI )

  2. Junko Akiyama, Ryuichi Okamoto, Michiko Iwasaki, Xiu Zheng, Shiro Yui, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe: Delta-like 1 expression promotes goblet cell differentiation in Notch-inactivated human colonic epithelial cells. Biochem. Biophys. Res. Commun. 2010.03; 393 (4): 662-667. ( PubMed , DOI )

  3. Sekiya I, Morito T, Hara K, Yamazaki J, Ju YJ, Yagishita K, Mochizuki T, Tsuji K, Muneta T: Ketoprofen absorption by muscle and tendon after topical or oral administration in patients undergoing anterior cruciate ligament reconstruction. AAPS PharmSciTech. 2010.03; 11 (1): 154-158. ( PubMed , DOI )

  1. Nikia Laurie, Adithi Mohan, Justina McEvoy, Damon Reed, Jiakun Zhang, Brett Schweers, Itsuki Ajioka, Virginia Valentine, Dianna Johnson, David Ellison, Michael A Dyer: Changes in retinoblastoma cell adhesion associated with optic nerve invasion. Mol. Cell. Biol.. 2009.12; 29 (23): 6268-6282. ( PubMed , DOI )

  2. Sekiya I, Tang T, Hayashi M, Morito T, Ju YJ, Mochizuki T, Muneta T: Periodic knee injections of BMP-7 delay cartilage degeneration induced by excessive running in rats. J Orthop Res. 2009.08; 27 (8): 1088-1092. ( PubMed , DOI )

  3. Funato N, Chapman SL, McKee MD, Funato H, Morris JA, Shelton JM, Richardson JA, Yanagisawa H: Hand2 controls osteoblast differentiation in the branchial arch by inhibiting DNA binding of Runx2. Development. 2009.02; 136 (4): 615-625. ( PubMed , DOI )

  1. Itsuki Ajioka, Michael A Dyer: A new model of tumor susceptibility following tumor suppressor gene inactivation. Cell Cycle. 2008.03; 7 (6): 735-740. ( PubMed )

  1. Barbosa AC, Funato N, Chapman S, McKee MD, Richardson JA, Olson EN, Yanagisawa H: Hand transcription factors cooperatively regulate development of the distal midline mesenchyme. Dev Biol. 2007.10; 310 (1): 154-168. ( PubMed , DOI )

  2. Itsuki Ajioka, Rodrigo A P Martins, Ildar T Bayazitov, Stacy Donovan, Dianna A Johnson, Sharon Frase, Samantha A Cicero, Kelli Boyd, Stanislav S Zakharenko, Michael A Dyer: Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice. Cell. 2007.10; 131 (2): 378-390. ( PubMed , DOI )

  3. Yuko Gonda, Hitoshi Sakurai, Yukio Hirata, Hidenori Tabata, Itsuki Ajioka, Kazunori Nakajima: Expression profiles of Insulin-like growth factor binding protein-like 1 in the developing mouse forebrain. Gene Expr. Patterns. 2007.02; 7 (4): 431-440. ( PubMed , DOI )

  4. Ohkuma M, Funato N, Higashihori N, Murakami M, Ohyama K, Nakamura M: Unique CCT repeats mediate transcription of the TWIST1 gene in mesenchymal cell lines. Biochem Biophys Res Commun. 2007.01; 352 (4): 925-931. ( PubMed , DOI )

  5. Takuya T Maeda, Itsuki Ajioka, Kazunori Nakajima: Computational cell model based on autonomous cell movement regulated by cell-cell signalling successfully recapitulates the "inside and outside" pattern of cell sorting. BMC Syst Biol. 2007; 1 43. ( PubMed , DOI )

  1. Itsuki Ajioka, Takuya Maeda, Kazunori Nakajima: Large-scale correlation of DNA accession numbers to the cDNAs in the FANTOM full-length mouse cDNA clone set. Keio J Med. 2006.09; 55 (3): 107-110. ( PubMed )

  2. Itsuki Ajioka, Takuya Maeda, Kazunori Nakajima: Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur. J. Neurosci.. 2006.01; 23 (2): 296-308. ( PubMed , DOI )

  1. Itsuki Ajioka, Kazunori Nakajima: Switching of alpha-catenin from alphaE-catenin in the cortical ventricular zone to alphaN-catenin II in the intermediate zone. Brain Res. Dev. Brain Res.. 2005.11; 160 (1): 106-111. ( PubMed , DOI )

  2. Itsuki Ajioka, Kazunori Nakajima: Birth-date-dependent segregation of the mouse cerebral cortical neurons in reaggregation cultures. Eur. J. Neurosci.. 2005.07; 22 (2): 331-342. ( PubMed , DOI )

  3. Chikako Kudo, Itsuki Ajioka, Yukio Hirata, Kazunori Nakajima: Expression profiles of EphA3 at both the RNA and protein level in the developing mammalian forebrain. J. Comp. Neurol.. 2005.07; 487 (3): 255-269. ( PubMed , DOI )

  4. Funato N, Twigg SR, Higashihori N, Ohyama K, Wall SA, Wilkie AO, Nakamura M: Functional analysis of natural mutations in two TWIST protein motifs. Hum Mutat. 2005.06; 25 (6): 550-556. ( PubMed , DOI )

  5. Sekiya I, Larson BL, Vuoristo JT, Reger RL, Prockop DJ: Comparison of effect of BMP-2, -4, and -6 on in vitro cartilage formation of human adult stem cells from bone marrow stroma. Cell Tissue Res. 2005.05; 320 (2): 269-276. ( PubMed , DOI )

  6. Funato N, Nohtomi-Ohyama J, Ohyama K: Monozygotic twins concordant for Crouzon syndrome. Am J Med Genet A. 2005.03; 133A (2): 225. ( PubMed , DOI )

  1. Takahashi E, Funato N, Higashihori N, Hata Y, Gridley T, Nakamura M: Snail regulates p21(WAF/CIP1) expression in cooperation with E2A and Twist. Biochem Biophys Res Commun. 2004.12; 325 (4): 1136-1144. ( PubMed , DOI )

  1. Kanda T, Funato N, Baba Y, Kuroda T: Evidence for fibroblast growth factor receptors in myofibroblasts during palatal mucoperiosteal repair. Arch Oral Biol. 2003.03; 48 (3): 213-221. ( PubMed )

  2. Funato N, Ohyama K, Kuroda T, Nakamura M: Basic helix-loop-helix transcription factor epicardin/capsulin/Pod-1 suppresses differentiation by negative regulation of transcription. J Biol Chem. 2003.02; 278 (9): 7486-7493. ( PubMed , DOI )

  1. Itsuki Ajioka, Toshihiro Akaike, Yoshifumi Watanabe: Ethanolamine is a co-mitogenic factor for proliferation of primary hepatocytes. J. Cell. Biochem.. 2002; 84 (2): 249-263. ( PubMed )

  1. Funato N, Ohtani K, Ohyama K, Kuroda T, Nakamura M: Common regulation of growth arrest and differentiation of osteoblasts by helix-loop-helix factors. Mol Cell Biol. 2001.11; 21 (21): 7416-7428. ( PubMed , DOI )

  2. Hatai T, Yokozeki M, Funato N, Baba Y, Moriyama K, Ichijo H, Kuroda T: Apoptosis of periodontal ligament cells induced by mechanical stress during tooth movement. Oral Dis. 2001.09; 7 (5): 287-290. ( PubMed )

  3. Sekiya I, Koopman P, Tsuji K, Mertin S, Harley V, Yamada Y, Shinomiya K, Nifuji A, Noda M: Dexamethasone enhances SOX9 expression in chondrocytes. J Endocrinol. 2001.06; 169 (3): 573-579. ( PubMed )

  4. I Ajioka, R Nishio, M Ikekita, T Akaike, M Sasaki, J Enami, Y Watanabe: Establishment of heterotropic liver tissue mass with direct link to the host liver following implantation of hepatocytes transfected with vascular endothelial growth factor gene in mice. Tissue Eng.. 2001.06; 7 (3): 335-344. ( PubMed , DOI )

  5. Sekiya I, Koopman P, Tsuji K, Mertin S, Harley V, Yamada Y, Shinomiya K, Niguji A, Noda M: Transcriptional suppression of Sox9 expression in chondrocytes by retinoic acid. J Cell Biochem Suppl. 2001; Suppl 36 71-78. ( PubMed )

  1. T Haruyama, I Ajioka, T Akaike, Y Watanabe: Regulation and significance of hepatocyte-derived matrix metalloproteinases in liver remodeling. Biochem. Biophys. Res. Commun.. 2000.06; 272 (3): 681-686. ( PubMed , DOI )

  2. Sekiya I, Tsuji K, Koopman P, Watanabe H, Yamada Y, Shinomiya K, Nifuji A, Noda M: SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6. J Biol Chem. 2000.04; 275 (15): 10738-10744. ( PubMed )

  1. Funato N, Moriyama K, Baba Y, Kuroda T: Evidence for apoptosis induction in myofibroblasts during palatal mucoperiosteal repair. J Dent Res. 1999.09; 78 (9): 1511-1517. ( PubMed )

  2. I Ajioka, T Akaike, Y Watanabe: Expression of vascular endothelial growth factor promotes colonization, vascularization, and growth of transplanted hepatic tissues in the mouse. Hepatology. 1999.02; 29 (2): 396-402. ( PubMed , DOI )

  1. Funato N, Moriyama K, Saitoh M, Baba Y, Ichijo H, Kuroda T: Evidence for apoptosis signal-regulating kinase 1 in the regenerating palatal epithelium upon acute injury. Lab Invest. 1998.04; 78 (4): 477-483. ( PubMed )

  2. Y Watanabe, I Ajioka, T Akaike: Gene transfection of multicellular spheroid of hepatocytes on an artificial substrate. Cytotechnology. 1998.01; 26 (1): 65-78. ( PubMed , DOI )

  1. Funato N, Moriyama K, Shimokawa H, Kuroda T: Basic fibroblast growth factor induces apoptosis in myofibroblastic cells isolated from rat palatal mucosa. Biochem Biophys Res Commun. 1997.11; 240 (1): 21-26. ( PubMed , DOI )

  2. Y Watanabe, S W Lee, M Detmar, I Ajioka, H F Dvorak: Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells. Oncogene. 1997.05; 14 (17): 2025-2032. ( PubMed , DOI )

  1. Funato N, Ohyama K, Nakamura M: Basic helix-loop-helix (bHLH) factors in osteoblast differentiation. J Oral Biosciences. 2002.09;

  1. Tanihata J, Nagata T, Ito N, Saito T, Nakamura A, Minamisawa S, Aoki Y, Ruegg UT, Takeda S: Truncated dystrophin ameliorates the dystrophic phenotype of mdx mice by reducing sarcolipin-mediated SERCA inhibition. Biochemical and biophysical research communications. 2018.09; ( PubMed , DOI )

  2. Zeniya S, Kuwahara H, Daizo K, Watari A, Kondoh M, Yoshida-Tanaka K, Kaburagi H, Asada K, Nagata T, Nagahama M, Yagi K, Yokota T: Angubindin-1 opens the blood-brain barrier in vivo for delivery of antisense oligonucleotide to the central nervous system. Journal of controlled release : official journal of the Controlled Release Society. 2018.05; ( PubMed , DOI )

  3. Komaki H*, Nagata T*, Saito T*, Masuda S, Takeshita E, Sasaki M, Tachimori H, Nakamura H, Aoki Y, Takeda S *Equal Contribution: Systemic administration of the antisense oligonucleotide NS-065/NCNP-01 for skipping of exon 53 in patients with Duchenne muscular dystrophy. Science translational medicine. 2018.04; 10 (437): ( PubMed , DOI )

  1. Echigoya Y, Nakamura A, Nagata T, Urasawa N, Lim KRQ, Trieu N, Panesar D, Kuraoka M, Moulton HM, Saito T, Aoki Y, Iversen P, Sazani P, Kole R, Maruyama R, Partridge T, Takeda S, Yokota T: Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America. 2017.04; 114 (16): 4213-4218. ( PubMed , DOI )

  1. Kimura K, Morita H, Daimon M, Kawata T, Nakao T, Lee SL, Hirokawa M, Ebihara A, Nakajima T, Ozawa T, Yonemochi Y, Aida I, Motoyoshi Y, Mikata T, Uchida I, Komori T, Kitao R, Nagata T, Takeda S, Komaki H, Segawa K, Takenaka K, Komuro I: Prognostic impact of venous thromboembolism in patients with Duchenne muscular dystrophy: Prospective multicenter 5-year cohort study. International journal of cardiology. 2015.07; 191 178-180. ( PubMed , DOI )

  2. Yoshioka K, Kuwahara H, Nishina K, Nagata T, Yokota T: [Recent progress and prospect in oligonucleotide therapeutics]. Nihon rinsho. Japanese journal of clinical medicine. 2015.06; 73 (6): 1057-1065. ( PubMed )

  3. Echigoya Y, Aoki Y, Miskew B, Panesar D, Touznik A, Nagata T, Tanihata J, Nakamura A, Nagaraju K, Yokota T: Long-term efficacy of systemic multiexon skipping targeting dystrophin exons 45-55 with a cocktail of vivo-morpholinos in mdx52 mice. 2015.02; 4 e225. ( PubMed , DOI )

  1. Re DB, Le Verche V, Yu C, Amoroso MW, Politi KA, Phani S, Ikiz B, Hoffmann L, Koolen M, Nagata T, Papadimitriou D, Nagy P, Mitsumoto H, Kariya S, Wichterle H, Henderson CE, Przedborski S: Necroptosis drives motor neuron death in models of both sporadic and familial ALS. Neuron. 2014.03; 81 (5): 1001-1008. ( PubMed , DOI )

  1. Aoki Y, Nagata T, Yokota T, Nakamura A, Wood MJ, Partridge T, Takeda S: Highly efficient in vivo delivery of PMO into regenerating myotubes and rescue in laminin-α2 chain-null congenital muscular dystrophy mice. Human molecular genetics. 2013.12; 22 (24): 4914-4928. ( PubMed , DOI )

  2. Kimura K, Takenaka K, Ebihara A, Uno K, Morita H, Nakajima T, Ozawa T, Aida I, Yonemochi Y, Higuchi S, Motoyoshi Y, Mikata T, Uchida I, Ishihara T, Komori T, Kitao R, Nagata T, Takeda S, Yatomi Y, Nagai R, Komuro I: Prognostic impact of left ventricular noncompaction in patients with Duchenne/Becker muscular dystrophy--prospective multicenter cohort study. International journal of cardiology. 2013.10; 168 (3): 1900-1904. ( PubMed , DOI )

  3. Echigoya Y, Lee J, Rodrigues M, Nagata T, Tanihata J, Nozohourmehrabad A, Panesar D, Miskew B, Aoki Y, Yokota T: Mutation types and aging differently affect revertant fiber expansion in dystrophic mdx and mdx52 mice. PloS one. 2013; 8 (7): e69194. ( PubMed , DOI )

  1. Yokota T, Nakamura A, Nagata T, Saito T, Kobayashi M, Aoki Y, Echigoya Y, Partridge T, Hoffman EP, Takeda S: Extensive and prolonged restoration of dystrophin expression with vivo-morpholino-mediated multiple exon skipping in dystrophic dogs. Nucleic acid therapeutics. 2012.10; 22 (5): 306-315. ( PubMed , DOI )

  2. Aoki Y, Yokota T, Nagata T, Nakamura A, Tanihata J, Saito T, Duguez SM, Nagaraju K, Hoffman EP, Partridge T, Takeda S: Bodywide skipping of exons 45-55 in dystrophic mdx52 mice by systemic antisense delivery. Proceedings of the National Academy of Sciences of the United States of America. 2012.08; 109 (34): 13763-13768. ( PubMed , DOI )

  1. Nagata T, Takeda S: Antisense oligos for muscular dystrophy. Rinsho shinkeigaku = Clinical neurology. 2010.11; 50 (11): 843. ( PubMed )

  1. Hoang T, Choi DK, Nagai M, Wu DC, Nagata T, Prou D, Wilson GL, Vila M, Jackson-Lewis V, Dawson VL, Dawson TM, Chesselet MF, Przedborski S: Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease. Free radical biology & medicine. 2009.10; 47 (7): 1049-1056. ( PubMed , DOI )

  1. Ohta Y, Kamiya T, Nagai M, Nagata T, Morimoto N, Miyazaki K, Murakami T, Kurata T, Takehisa Y, Ikeda Y, Asoh S, Ohta S, Abe K: Therapeutic benefits of intrathecal protein therapy in a mouse model of amyotrophic lateral sclerosis. Journal of neuroscience research. 2008.10; 86 (13): 3028-3037. ( PubMed , DOI )

  1. Nagata T, Nagano I, Shiote M, Narai H, Murakami T, Hayashi T, Shoji M, Abe K: Elevation of MCP-1 and MCP-1/VEGF ratio in cerebrospinal fluid of amyotrophic lateral sclerosis patients. Neurological research. 2007.12; 29 (8): 772-776. ( PubMed , DOI )

  2. Nagata T, Ilieva H, Murakami T, Shiote M, Narai H, Ohta Y, Hayashi T, Shoji M, Abe K: Increased ER stress during motor neuron degeneration in a transgenic mouse model of amyotrophic lateral sclerosis. Neurological research. 2007.12; 29 (8): 767-771. ( PubMed , DOI )

  3. Nagai M, Re DB, Nagata T, Chalazonitis A, Jessell TM, Wichterle H, Przedborski S: Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nature neuroscience. 2007.05; 10 (5): 615-622. ( PubMed , DOI )

  4. Hirano M, Yamamoto A, Mori T, Lan L, Iwamoto TA, Aoki M, Shimada K, Furiya Y, Kariya S, Asai H, Yasui A, Nishiwaki T, Imoto K, Kobayashi N, Kiriyama T, Nagata T, Konishi N, Itoyama Y, Ueno S: DNA single-strand break repair is impaired in aprataxin-related ataxia. Annals of neurology. 2007.02; 61 (2): 162-174. ( PubMed , DOI )

  1. Ohta Y, Nagai M, Nagata T, Murakami T, Nagano I, Narai H, Kurata T, Shiote M, Shoji M, Abe K: Intrathecal injection of epidermal growth factor and fibroblast growth factor 2 promotes proliferation of neural precursor cells in the spinal cords of mice with mutant human SOD1 gene. Journal of neuroscience research. 2006.10; 84 (5): 980-992. ( PubMed , DOI )

  2. Iwai M, Ikeda T, Hayashi T, Sato K, Nagata T, Nagano I, Shoji M, Ikenoue T, Abe K: Temporal profile of neural stem cell proliferation in the subventricular zone after ischemia/hypoxia in the neonatal rat brain. Neurological research. 2006.06; 28 (4): 461-468. ( PubMed , DOI )

  1. Suzuki N, Aoki M, Mizuno H, Onodera Y, Takahashi T, Nagata T, Tateyama M, Itoyama Y: Late-onset distal myopathy with rimmed vacuoles without mutation in the GNE or dysferlin genes. Muscle & nerve. 2005.12; 32 (6): 812-814. ( PubMed , DOI )

  2. Narai H, Nagano I, Ilieva H, Shiote M, Nagata T, Hayashi T, Shoji M, Abe K: Prevention of spinal motor neuron death by insulin-like growth factor-1 associating with the signal transduction systems in SODG93A transgenic mice. Journal of neuroscience research. 2005.11; 82 (4): 452-457. ( PubMed , DOI )

  3. Matsubara E, Nagata T, Kageyama Y, Shiote M, Namba R, Nagano I, Shoji M, Abe K: Unique cerebellar-cerebral form of autosomal recessive ataxia. The Tohoku journal of experimental medicine. 2005.09; 207 (1): 81-85. ( PubMed )

  4. Shiote M, Nagano I, Ilieva H, Murakami T, Narai H, Ohta Y, Nagata T, Shoji M, Abe K: Reduction of a vascular endothelial growth factor receptor, fetal liver kinase-1, by antisense oligonucleotides induces motor neuron death in rat spinal cord exposed to hypoxia. Neuroscience. 2005.01; 132 (1): 175-182. ( PubMed , DOI )

  1. Murakami T, Ilieva H, Shiote M, Nagata T, Nagano I, Shoji M, Abe K: Hypoxic induction of vascular endothelial growth factor is selectively impaired in mice carrying the mutant SOD1 gene. Brain research. 2003.11; 989 (2): 231-237. ( PubMed )

  2. Sakurai M, Nagata T, Abe K, Horinouchi T, Itoyama Y, Tabayashi K: Survival and death-promoting events after transient spinal cord ischemia in rabbits: induction of Akt and caspase3 in motor neurons. The Journal of thoracic and cardiovascular surgery. 2003.02; 125 (2): 370-377. ( PubMed , DOI )

  3. Sakurai M, Nagata T, Abe K, Horinouchi T, Itoyama Y, Tabayashi K: Oxidative damage and reduction of redox factor-1 expression after transient spinal cord ischemia in rabbits. Journal of vascular surgery. 2003.02; 37 (2): 446-452. ( PubMed , DOI )

  1. Nishino I, Noguchi S, Murayama K, Driss A, Sugie K, Oya Y, Nagata T, Chida K, Takahashi T, Takusa Y, Ohi T, Nishimiya J, Sunohara N, Ciafaloni E, Kawai M, Aoki M, Nonaka I: Distal myopathy with rimmed vacuoles is allelic to hereditary inclusion body myopathy. Neurology. 2002.12; 59 (11): 1689-1693. ( PubMed )

  1. Moreira MC, Barbot C, Tachi N, Kozuka N, Uchida E, Gibson T, Mendonça P, Costa M, Barros J, Yanagisawa T, Watanabe M, Ikeda Y, Aoki M, Nagata T, Coutinho P, Sequeiros J, Koenig M: The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin. Nature genetics. 2001.10; 29 (2): 189-193. ( PubMed , DOI )

  2. Nagata T, Aoki M, Hasegawa T, Shiga Y, Hayashi T, Higuchi J, Abe K, Tanno T, Konno H, Itoyama Y: [An autopsy case of atypical Friedreich's ataxia with chronic idiopathic intestinal pseudo-obstruction]. Rinsho shinkeigaku = Clinical neurology. 2001.07; 41 (7): 412-417. ( PubMed )

  3. Nagata T, Onodera H, Ohuchi M, Suzuki Y, Tago H, Fujihara K, Ishii N, Sugamura K, Shoji Y, Handa M, Tabayashi K, Itoyama Y: Decreased expression of c-myc family genes in thymuses from myasthenia gravis patients. Journal of neuroimmunology. 2001.04; 115 (1-2): 199-202. ( PubMed )

  1. Onodera J, Nagata T, Fujihara K, Ohuchi M, Ishii N, Sugamura K, Itoyama Y: Expression of OX40 and OX40 ligand (gp34) in the normal and myasthenic thymus. Acta neurologica Scandinavica. 2000.10; 102 (4): 236-243. ( PubMed )

  2. Onodera Y, Aoki M, Tsuda T, Kato H, Nagata T, Kameya T, Abe K, Itoyama Y: High prevalence of spinocerebellar ataxia type 1 (SCA1) in an isolated region of Japan. Journal of the neurological sciences. 2000.09; 178 (2): 153-158. ( PubMed )

  1. Onodera H, Nakashima I, Fujihara K, Nagata T, Itoyama Y: Elevated plasma level of plasminogen activator inhibitor-1 (PAI-1) in patients with relapsing-remitting multiple sclerosis. The Tohoku journal of experimental medicine. 1999.12; 189 (4): 259-265. ( PubMed )

  2. Onodera H, Nagata T, Kanazawa M, Taguma Y, Itoyama Y: Increased plasma GDNF levels in patients with chronic renal diseases. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 1999.06; 14 (6): 1604-1605. ( PubMed )

  3. Kikuchi A, Chida K, Misu T, Okita N, Takase S, Nagata T, Sakai K, Itoyama Y: [A case of limbic encephalitis associated with breast cancer developed in an HTLV-1 carrier]. Rinsho shinkeigaku = Clinical neurology. 1999.05; 39 (5): 555-559. ( PubMed )

  1. Aoki M, Abe K, Nagata T, Kameya T, Watanabe M, Onodera H, Mochizuki H, Itoyama Y: A Japanese family with Machado-Joseph disease characterized by initial emaciation and myoclonus. European journal of neurology : the official journal of the European Federation of Neurological Societies. 1995.11; 2 (5): 477-482. ( PubMed , DOI )

  2. Hayashi T, Onodera J, Nagata T, Mochizuki H, Itoyama Y: [A case of biopsy-proven sarcoid meningoencephalitis presented with hallucination, nominal aphasia and dementia]. Rinsho shinkeigaku = Clinical neurology. 1995.09; 35 (9): 1008-1011. ( PubMed )

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