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Maki Asami, Brian Y H Lam, Martin Hoffmann, Toru Suzuki, Xin Lu, Naoko Yoshida, Marcella K Ma, Kara Rainbow, Miodrag Gužvić, Matthew D VerMilyea, Giles S H Yeo, Christoph A Klein, Anthony C F Perry: A program of successive gene expression in mouse one-cell embryos. Cell Rep. 2023.01; 42 (2): 112023. ( PubMed , DOI )

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Shizuka Kirino, Analia Yogi, Eriko Adachi, Hisae Nakatani, Maki Gau, Ryosei Iemura, Haruki Yamano, Toru Kanamori, Takayasu Mori, Eisei Sohara, Shinichi Uchida, Kentaro Okamoto, Tomohiro Udagawa, Kei Takasawa, Tomohiro Morio, Kenichi Kashimada: Phenotypic Variation in 46,XX Disorders of Sex Development due to the Fourth Zinc Finger Domain Variant of WT1: A Familial Case Report. Sex Dev. 2023; 17 (1): 51-55. ( PubMed , DOI )

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Aoyama Jiro, Osaka Mizuko, Deushi Michiyo, Hosoya Shoichi, Ishigami Akihito, Maehara Taketoshi, Yoshida Masayuki: CXCL1刺激によるPAD4の細胞質移行はPDIA1のシトルリン化を介して好中球の接着を亢進する(CXCL1-Triggered PAD4 Cytoplasmic Translocation Enhances Neutrophil Adhesion through Citrullination of PDIA1) Journal of Atherosclerosis and Thrombosis. 2022.09; 29 (9): 1307-1318. ( ichushi )

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Yomogita H, Miyasaka N, Kanai-Azuma M: A Review of Delayed Delivery Models and the Analysis Method in Mice. Journal of developmental biology. 2022.05; 10 (2): ( PubMed , DOI )

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Mami Oikawa, Hisato Kobayashi, Makoto Sanbo, Naoaki Mizuno, Kenyu Iwatsuki, Tomoya Takashima, Keiko Yamauchi, Fumika Yoshida, Takuya Yamamoto, Takashi Shinohara, Hiromitsu Nakauchi, Kazuki Kurimoto, Masumi Hirabayashi, Toshihiro Kobayashi: Functional primordial germ cell-like cells from pluripotent stem cells in rats. Science. 2022.04; 376 (6589): 176-179. ( PubMed , DOI )

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Aoyama J, Osaka M, Deushi M, Hosoya S, Ishigami A, Maehara T, Yoshida M: CXCL1-Triggered PAD4 Cytoplasmic Translocation Enhances Neutrophil Adhesion through Citrullination of PDIA1. Journal of atherosclerosis and thrombosis. 2021.12; 29 (9): 1307-1318. ( PubMed , DOI )

Yoshiko Ishisaka, Nobuyuki Nosaka, Yuka Mishima, Takahiro Masuda, Michio Nagashima, Yosuke Tanaka, Kouhei Yamamoto, Masayuki Yoshida, Hidenobu Shigemitsu: COVID-19 case of ventilator-induced lung injury on extracorporeal membrane oxygenation: Physicians' clinical struggle and ethical conflict in a novel pandemic. Clin Case Rep. 2021.12; 9 (12): e05223. ( PubMed , DOI )

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Yusuke Ebana, Sou Hee Yang, Megumu Yokono, Masayuki Yoshida: Establishment of the Certified Research Ethics Professionals: An Ethical Review Expert -Translated in English from Japanese Version. JMA J. 2021.10; 4 (4): 405-408. ( PubMed , DOI )

Saito Yoko, Takasawa Kei, Gau Maki, Yamauchi Takeru, Nakagawa Ryuichi, Miyakawa Yuichi, Sutani Akito, Hosokawa-Tsuji Atsumi, Takishima Shigeru, Matsubara Yohei, Morio Tomohiro, Kashimada Kenichi: Adrenal suppression and anthropometric data at two years of age was not influenced by the initial hydrocortisone dose in patients with 21-hydroxylase deficiency Clinical Pediatric Endocrinology. 2021.10; 30 (4): 155-161. ( ichushi )

Ebana Yusuke, Yang Sou Hee, Yokono Megumu, Yoshida Masayuki: Establishment of the Certified Research Ethics Professionals: An Ethical Review Expert: Translated in English from Japanese Version(和訳中) JMA Journal. 2021.10; 4 (4): 405-408. ( ichushi )

Yumi Inagaki, Takuya Ogawa, Makoto J Tabata, Yuki Nagata, Ryo Watanabe, Tatsuo Kawamoto, Keiji Moriyama, Toshihiro Tanaka: Identification of OPN3 as associated with non-syndromic oligodontia in a Japanese population. J Hum Genet. 2021.08; 66 (8): 769-775. ( PubMed , DOI )

Ikeda Sadakatsu, Kudo Ryo, Yamashita Yamato, Noji Rika, Yokobori Jyunko, Ohki Mika, Takamine Eriko, Kobayashi Yumi, Egawa Makiko, Ebana Yusuke, Kimura Koichiro, Yokoyama Kohta, Onishi Iichiro, Takemoto Akira, Kirimura Susumu, Kinowaki Yuko, Tanimoto Kosuke, Miya Fuyuki, Kano Yoshihito, Yoshida Masayuki, Miyake Satoshi. : Clinical utility of multi-disciplinary expert panel discussion in precision cancer medicine ANNALS OF ONCOLOGY.. 2021.07; ( DOI )

Masuda T, Uchimido R, Nosaka N, Akiyama H, Kamisato A, Yoshida M: Concerns in Methodology for Self-Administered Questionnaire: Needs for Involvement of Social Scientists. Chest. 2021.07; 160 (1): e92-e93. ( PubMed , DOI )

Ikeda Sadakatsu, Kudo Ryo, Yamashita Yamato, Noji Rika, Yokobori Jyunko, Ohki Mika, Takamine Eriko, Kobayashi Yumi, Egawa Makiko, Ebana Yusuke, Kimura Koichiro, Yokoyama Kohta, Onishi Iichiro, Takemoto Akira, Kirimura Susumu, Kinowaki Yuko, Tanimoto Kosuke, Miya Fuyuki, Kano Yoshihito, Yoshida Masayuki, Miyake Satoshi: Clinical utility of multi-disciplinary expert panel discussion in precision cancer medicine ANNALS OF ONCOLOGY. 2021.07; 32 S287. ( DOI )

Osaka M, Deushi M, Aoyama J, Funakoshi T, Ishigami A, Yoshida M: High-Fat Diet Enhances Neutrophil Adhesion in LDLR-Null Mice Via Hypercitrullination of Histone H3. JACC. Basic to translational science. 2021.06; 6 (6): 507-523. ( PubMed , DOI )

Laura Santini, Florian Halbritter, Fabian Titz-Teixeira, Toru Suzuki, Maki Asami, Xiaoyan Ma, Julia Ramesmayer, Andreas Lackner, Nick Warr, Florian Pauler, Simon Hippenmeyer, Ernest Laue, Matthias Farlik, Christoph Bock, Andreas Beyer, Anthony C. F. Perry, Martin Leeb: Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3 Nature Communications. 2021.06; ( PubMed , DOI )

Kei Takasawa, Yuichi Miyakawa, Yoko Saito, Eriko Adachi, Tsunanori Shidei, Akito Sutani, Maki Gau, Ryuichi Nakagawa, Atsuko Taki, Kenichi Kashimada, Tomohiro Morio: Marked clinical heterogeneity in congenital hyperinsulinism due to a novel homozygous ABCC8 mutation. Clin Endocrinol (Oxf). 2021.06; 94 (6): 940-948. ( PubMed , DOI )

Hirate Yoshikazu, Hayakawa Kana, Nakano Yuki, Kumazawa Shiori, Miura Kento, Kanai Yoshiakira, Kanai-Azuma Masami: Role of SOX17 in crypt formation and regulation of SOX9 and AREG expression at the implantation site(和訳中) Experimental Animals. 2021.06; 70 (Suppl.): S61. ( ichushi )

Matsuzawa Ayumi, Lee Jiyoung, Nakagawa So, Itoh Johbu, Takahashi Ueda Mahoko, Mitsuhashi Satomi, Kochi Yuta, Kaneko-Ishino Tomoko, Ishino Fumitoshi: HERV-Derived Ervpb1 Is Conserved in Simiiformes, Exhibiting Expression in Hematopoietic Cell Lineages Including Macrophages INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021.05; 22 (9): ( DOI )

Todd A Johnson, Yoichi Mashimo, Jer-Yuarn Wu, Dankyu Yoon, Akira Hata, Michiaki Kubo, Atsushi Takahashi, Tatsuhiko Tsunoda, Kouichi Ozaki, Toshihiro Tanaka, Kaoru Ito, Hiroyuki Suzuki, Hiromichi Hamada, Tohru Kobayashi, Toshiro Hara, Chien-Hsiun Chen, Yi-Ching Lee, Yi-Min Liu, Li-Ching Chang, Chun-Ping Chang, Young-Mi Hong, Gi-Young Jang, Sin-Weon Yun, Jeong-Jin Yu, Kyung-Yil Lee, Jae-Jung Kim, Taesung Park, , Jong-Keuk Lee, Yuan-Tsong Chen, Yoshihiro Onouchi: Association of an IGHV3-66 gene variant with Kawasaki disease. J Hum Genet. 2021.05; ( PubMed , DOI )

Myunghee Hong, Yusuke Ebana, Jaemin Shim, Eue-Keun Choi, Hong Euy Lim, Inseok Hwang, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Boyoung Joung, Seil Oh, Moon-Hyoung Lee, Young-Hoon Kim, Sun Ha Jee, Hui-Nam Pak: Ethnic similarities in genetic polymorphisms associated with atrial fibrillation: Far East Asian vs European populations. Eur J Clin Invest. 2021.05; e13584. ( PubMed , DOI )

Okiko Habara, Catriona Y Logan, Masami Kanai-Azuma, Roeland Nusse, Hinako M Takase: WNT signaling in pre-granulosa cells is required for ovarian folliculogenesis and female fertility. Development. 2021.05; 148 (9): ( PubMed , DOI )

Dewan SMR, Osaka M, Deushi M, Yoshida M: Complement C5a-triggered differentiated HL-60 stimulates migration of THP-1 monocytic leukocytes via secretion of CCL2. FEBS open bio. 2021.03; ( PubMed , DOI )

Tsuru Hiromi, Osaka Mizuko, Yoshida Masayuki: Complement Factor D Facilitates the Development of Fatty Liver under Long-term but not Short-term High-fat Diet-feeding Conditions(和訳中) 日本循環器学会学術集会抄録集. 2021.03; 85回 OE113-3. ( ichushi )

Dewan Syed Masudur Rahman, Osaka Mizuko, Deushi Michiyo, Yoshida Masayuki: C5a-stimulated Neutrophil-like Differentiated HL-60 Induced Migration of Monocytic THP-1 through the Secretion of MCP-1(和訳中) 日本循環器学会学術集会抄録集. 2021.03; 85回 OE029-5. ( ichushi )

Yoshikazu Hirate, Kana Hayakawa, Yuki Nakano, Shiori Kumazawa, Kento Miura, Yoshiakira Kanai, Masami Kanai-Azuma: Early Crypt Formation Defects in the Uterine Epithelia of Sox17 Heterozygous Mice. Sex Dev. 2021.03; 14 (1-6): 40-50. ( PubMed , DOI )

Nagaoka E, Arai H, Ugawa T, Masuda T, Ochiai K, Tamaoka M, Kurashima N, Oi K, Fujiwara T, Yoshida M, Shigemitsu H, Otomo Y: Efficacy of Multidisciplinary Team Approach with Extracorporeal Membrane Oxygenation for COVID-19 in Low Volume ECMO center. Artificial organs. 2021.03; 45 (9): 1061-1067. ( PubMed , DOI )

Yamazoe M, Sasano T, Ihara K, Takahashi K, Nakamura W, Takahashi N, Komuro H, Hamada S, Furukawa T: Sparsely methylated mitochondrial cell free DNA released from cardiomyocytes contributes to systemic inflammatory response accompanied by atrial fibrillation. Scientific reports. 2021.03; 11 (1): 5837. ( PubMed , DOI )

Maki Gau, Kaoru Konishi, Kei Takasawa, Ryuichi Nakagawa, Atsumi Tsuji-Hosokawa, Atsuko Hashimoto, Akito Sutani, Toshihiro Tajima, Tomonobu Hasegawa, Tomohiro Morio, Kenichi Kashimada: The progression of salt-wasting and the body weight change during the first 2 weeks of life in classical 21-hydroxylase deficiency patients. Clin Endocrinol (Oxf). 2021.02; 94 (2): 229-236. ( PubMed , DOI )

Naito Yoichi, Aburatani Hiroyuki, Amano Toraji, Baba Eishi, Furukawa Toru, Hayashida Tetsu, Hiyama Eiso, Ikeda Sadakatsu, Kanai Masashi, Kato Motohiro, Kinoshita Ichiro, Kiyota Naomi, Kohno Takashi, Kohsaka Shinji, Komine Keigo, Matsumura Itaru, Miura Yuji, Nakamura Yoshiaki, Natsume Atsushi, Nishio Kazuto, Oda Katsutoshi, Oda Naoyuki, Okita Natsuko, Oseto Kumiko, Sunami Kuniko, Takahashi Hideaki, Takeda Masayuki, Tashiro Shimon, Toyooka Shinichi, Ueno Hideki, Yachida Shinichi, Yoshino Takayuki, Tsuchihara Katsuya: Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2.1) INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY. 2021.02; 26 (2): 233-283. ( PubMed , DOI )

Kasane Imura-Kishi, Aya Uchida, Naoki Tsunekawa, Hitomi Suzuki, Hinako M Takase, Yoshikazu Hirate, Masami Kanai-Azuma, Ryuji Hiramatsu, Masamichi Kurohmaru, Yoshiakira Kanai: Low retinoic acid levels mediate regionalization of the Sertoli valve in the terminal segment of mouse seminiferous tubules. Sci Rep. 2021.01; 11 (1): 1110. ( PubMed , DOI )

Tadashi Shin, Yuichi Hiraoka, Tokiwa Yamasaki, Jamey D Marth, Josef M Penninger, Masami Kanai-Azuma, Kohichi Tanaka, Satoshi Kofuji, Hiroshi Nishina: MKK7 deficiency in mature neurons impairs parental behavior in mice. Genes Cells. 2021.01; 26 (1): 5-17. ( PubMed , DOI )

Kitazawa M., Sutani A., Kaneko-Ishino T. and Ishino F.: The role of eutherian-specific RTL1 in the nervous system and its implications for the Kagami-Ogata and Temple syndromes. Genes to cells. 2021.01; ( DOI )

Yamashita S, Masuda D, Akishita M, Arai H, Asada Y, Dobashi K, Egashira K, Harada-Shiba M, Hirata K, Ishibashi S, Kajinami K, Kinoshita M, Kozaki K, Kuzuya M, Ogura M, Okamura T, Sato K, Shimano H, Tsukamoto K, Yokode M, Yokote K, Yoshida M: Guidelines on the Clinical Evaluation of Medicinal Products for Treatment of Dyslipidemia. Journal of atherosclerosis and thrombosis. 2020.11; 27 (11): 1246-1254. ( PubMed , DOI )

Yamashita Shizuya, Masuda Daisaku, Akishita Masahiro, Arai Hidenori, Asada Yujiro, Dobashi Kazushige, Egashira Kensuke, Harada-Shiba Mariko, Hirata Kenichi, Ishibashi Shun, Kajinami Kouji, Kinoshita Makoto, Kozaki Koichi, Kuzuya Masafumi, Ogura Masatsune, Okamura Tomonori, Sato Kayoko, Shimano Hitoshi, Tsukamoto Kazuhisa, Yokode Masayuki, Yokote Koutaro, Yoshida Masayuki: 脂質異常症治療に使用される医薬品の臨床評価に関するガイドライン(Guidelines on the Clinical Evaluation of Medicinal Products for Treatment of Dyslipidemia) Journal of Atherosclerosis and Thrombosis. 2020.11; 27 (11): 1246-1254. ( ichushi )

Marta Duch, Núria Torras, Maki Asami, Toru Suzuki, María Isabel Arjona, Rodrigo Gómez-Martínez, Matthew D VerMilyea, Robert Castilla, José Antonio Plaza, Anthony C F Perry : Tracking intracellular forces and mechanical property changes in mouse one-cell embryo development Nature Materials. 2020.10; 19 (10): 1114-1123. ( PubMed , DOI )

Tsuru H, Osaka M, Hiraoka Y, Yoshida M: HFD-induced hepatic lipid accumulation and inflammation are decreased in Factor D deficient mouse. Scientific reports. 2020.10; 10 (1): 17593. ( PubMed , DOI )

Takeru Yamauchi, Masatoshi Imamura, Kei Takasawa, Keisuke Nakajima, Ryuichi Nakagawa, Maki Gau, Manabu Sugie, Atsuko Taki, Masahiko Kawai, Kenichi Kashimada, Tomohiro Morio: Prematurity at less than 24 weeks of gestation is a risk for prolonged hyperglycemia in extremely low-birth weight infants Endocrine. 2020.10; 70 (1): 71-77. ( PubMed , DOI )

Xiaoxi Yang, Tetsuo Sasano, Yusuke Ebana, Jun K Takeuchi, Kensuke Ihara, Masahiro Yamazoe, Tetsushi Furukawa: Functional Role of the L396R Mutation of Tks5 Identified by an Exome-Wide Association Study in Atrial Fibrillation. Circ J. 2020.10; ( PubMed , DOI )

Kitazawa M, Hayashi S, Imamura M, Takeda S, Oishi Y, Kaneko-Ishino T, Ishino F: Deficiency and overexpression of Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Kagami-Ogata syndromes. Development (Cambridge, England). 2020.09; 147 (21): ( PubMed , DOI )

Catherine E Lipovsky, Jesus Jimenez, Qiusha Guo, Gang Li, Tiankai Yin, Stephanie C Hicks, Somya Bhatnagar, Kentaro Takahashi, David M Zhang, Brittany D Brumback, Uri Goldsztejn, Rangarajan D Nadadur, Carlos Perez-Cervantez, Ivan P Moskowitz, Shaopeng Liu, Bo Zhang, Stacey L Rentschler: Chamber-specific transcriptional responses in atrial fibrillation. JCI Insight. 2020.09; 5 (18): ( PubMed , DOI )

Nouchi R, Aihara H, Arie F, Asashima M, Daida H, Fudano J, Fujiwara Y, Fushiki S, Geller RJ, Hatano K, Homma T, Kimura M, Kuroki T, Miki K, Morita I, Nitta K, Shinohara A, Siomi MC, Yoshida M, Ichikawa I: Toward global standardization of conducting fair investigations of allegations of research misconduct. Accountability in research. 2020.08; 27 (6): 327-346. ( PubMed , DOI )

Egawa M, Hara K, Ikeda M, Yoshida M: Questionnaire dataset: Attitude of epileptologists and obstetricians to pregnancy among women with epilepsy. Data in brief. 2020.08; 31 105948. ( PubMed , DOI )

Ohsugi Y, Katagiri S, Hirota T, Niimi H, Hatasa M, Watanabe K, Shimohira T, Mizutani K, Kitazawa M, Matsuzawa A, Kadokura H, Yokose S, Iwata T, Aoki A: Laser irradiation decreases sclerostin expression in bone and osteogenic cells. The FASEB Journal. 2020.08; 34 (9): 12877-12893. ( PubMed , DOI )

Hiroko Terui-Kohbata, Masami Ikeda, Kei Yura: The reliability and validity of the Japanese version of Revised Illness Perception Questionnaires for Healthy people (IPQ-RH-J) British Journal of Cancer Research. 2020.08; 3 (2): 341-348. ( DOI )

Dewan Syed Masudur Rahman, Deushi Michiyo, Osaka Mizuko, Yoshida Masayuki: 分化したHL60のC5aによる刺激はMCP-1依存的経路を介してTHP-1走化性を誘導する(C5a stimulation of differentiated HL60 induces THP-1 chemotaxis via MCP-1 dependent pathway) 日本動脈硬化学会総会プログラム・抄録集. 2020.07; 52回 268. ( ichushi )

Dewan Syed Masudur Rahman, Deushi Michiyo, Osaka Mizuko, Yoshida Masayuki: C5aは好中球様細胞へ分化したHL60においてNF-κBシグナル伝達経路を介してMCP-1発現を上昇させる(C5a Elevates MCP-1 Expression in Neutrophil-like Differentiated HL60 via NF-κ B Signaling Pathway) 日本循環器学会学術集会抄録集. 2020.07; 84回 OE122-6. ( ichushi )

Tsuru Hiromi, Osaka Mizuko, Yoshida Masayuki: 高脂肪食誘発性脂肪肝の発症において補体D因子が果たす重要な役割(Critical Role of Complement Factor D in the Development of High-fat Diet-induced Fatty Liver) 日本循環器学会学術集会抄録集. 2020.07; 84回 PE28-2. ( ichushi )

Yoshida Masayuki: 血栓症研究　最新情報　高脂肪食誘発性アテローム性血管炎の進行におけるvital NETosisの関与(Thrombosis Research -Update-　Involvement of Vital NETosis in the Progression of High Fat Diet-induced Atherogenic Vascular Inflammation) 日本循環器学会学術集会抄録集. 2020.07; 84回 Symposium9-4. ( ichushi )

Ishigaki K, Akiyama M, Kanai M, Takahashi A, Kawakami E, Sugishita H, Sakaue S, Matoba N, Low SK, Okada Y, Terao C, Amariuta T, Gazal S, Kochi Y, Horikoshi M, Suzuki K, Ito K, Koyama S, Ozaki K, Niida S, Sakata Y, Sakata Y, Kohno T, Shiraishi K, Momozawa Y, Hirata M, Matsuda K, Ikeda M, Iwata N, Ikegawa S, Kou I, Tanaka T, Nakagawa H, Suzuki A, Hirota T, Tamari M, Chayama K, Miki D, Mori M, Nagayama S, Daigo Y, Miki Y, Katagiri T, Ogawa O, Obara W, Ito H, Yoshida T, Imoto I, Takahashi T, Tanikawa C, Suzuki T, Sinozaki N, Minami S, Yamaguchi H, Asai S, Takahashi Y, Yamaji K, Takahashi K, Fujioka T, Takata R, Yanai H, Masumoto A, Koretsune Y, Kutsumi H, Higashiyama M, Murayama S, Minegishi N, Suzuki K, Tanno K, Shimizu A, Yamaji T, Iwasaki M, Sawada N, Uemura H, Tanaka K, Naito M, Sasaki M, Wakai K, Tsugane S, Yamamoto M, Yamamoto K, Murakami Y, Nakamura Y, Raychaudhuri S, Inazawa J, Yamauchi T, Kadowaki T, Kubo M, Kamatani Y: Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Nature genetics. 2020.07; 52 (7): 669-679. ( PubMed , DOI )

Terui-Kohbata Hiroko, Egawa Makiko, Yura Kei, Yoshida Masayuki: Knowledge and attitude of hereditary breast cancer among Japanese university female students Journal of Human Genetics. 2020.07; 65 (7): 591-599. ( ichushi )

Egawa M, Hara K, Ikeda M, Kono E, Miyashita S, Miyasaka N, Inaji M, Maehara T, Yoshida M: Role of obstetricians in promoting pregnancy-related knowledge among women with epilepsy in Japan. Epilepsy & behavior : E&B. 2020.06; 111 107176. ( PubMed , DOI )

Pattarapanawan M, Uemura M, Miyazaki N, Takami S, Tomiyasu H, Tsunekawa N, Hirate Y, Fujishiro J, Kurohmaru M, Kanai-Azuma M, Higashiyama H, Kanai Y: Anatomical and histological characteristics of the hepatobiliary system in adult Sox17 heterozygote mice. Anatomical record (Hoboken, N.J. : 2007). 2020.06; 303 (12): 3096-3107. ( PubMed , DOI )

Yoshida Hiroshi, Tada Hayato, Ito Kumie, Kishimoto Yoshimi, Yanai Hidekatsu, Okamura Tomonori, Ikewaki Katsunori, Inagaki Kyoko, Shoji Tetsuo, Bujo Hideaki, Miida Takashi, Yoshida Masayuki, Kuzuya Masafumi, Yamashita Shizuya: 健康な日本人における血清非コレステロールステロールの男女別基準値(Reference Intervals of Serum Non-Cholesterol Sterols by Gender in Healthy Japanese Individuals) Journal of Atherosclerosis and Thrombosis. 2020.05; 27 (5): 409-417. ( ichushi )

Yoshiki Higashijima, Yusuke Matsui, Teppei Shimamura, Ryo Nakaki, Nao Nagai, Shuichi Tsutsumi, Yohei Abe, Verena M Link, Mizuko Osaka, Masayuki Yoshida, Ryo Watanabe, Toshihiro Tanaka, Akashi Taguchi, Mai Miura, Xiaoan Ruan, Guoliang Li, Tsuyoshi Inoue, Masaomi Nangaku, Hiroshi Kimura, Tetsushi Furukawa, Hiroyuki Aburatani, Youichiro Wada, Yijun Ruan, Christopher K Glass, Yasuharu Kanki: Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells. EMBO J. 2020.04; 39 (7): e103949. ( PubMed , DOI )

Mami Uemura, Mayumi Higashi, Montri Pattarapanawan, Shohei Takami, Naoki Ichikawa, Hiroki Higashiyama, Taizo Furukawa, Jun Fujishiro, Yuki Fukumura, Takashi Yao, Tatsuro Tajiri, Masami Kanai-Azuma, Yoshiakira Kanai: Gallbladder wall abnormality in biliary atresia of mouse Sox17 +/- neonates and human infants Dis Model Mech. 2020.04; 13 (4): ( PubMed , DOI )

Fukaishi Takahiro, Minami Isao, Masuda Seizaburo, Miyachi Yasutaka, Tsujimoto Kazutaka, Izumiyama Hajime, Hashimoto Koshi, Yoshida Masayuki, Takahashi Sayako, Kashimada Kenichi, Morio Tomohiro, Kosaki Kenjiro, Maezawa Yoshiro, Yokote Koutaro, Yoshimoto Takanobu, Yamada Tetsuya: A case of generalized lipodystrophy-associated progeroid syndrome treated by leptin replacement with short and long-term monitoring of the metabolic and endocrine profiles(和訳中) Endocrine Journal. 2020.02; 67 (2): 211-218. ( ichushi )

Takahiro Fukaishi, Isao Minami, Seizaburo Masuda, Yasutaka Miyachi, Kazutaka Tsujimoto, Hajime Izumiyama, Koshi Hashimoto, Masayuki Yoshida, Sayako Takahashi, Kenichi Kashimada, Tomohiro Morio, Kenjiro Kosaki, Yoshiro Maezawa, Koutaro Yokote, Takanobu Yoshimoto, Tetsuya Yamada: A case of generalized lipodystrophy-associated progeroid syndrome treated by leptin replacement with short and long-term monitoring of the metabolic and endocrine profiles. Endocr. J.. 2020.02; 67 (2): 211-218. ( PubMed , DOI )

Yamada, T, Takechi M (Co-first), Yokoyama N, Hiraoka Y, Ishikubo H, Usami T, Furutera T, Taga Y, Hirate Y, Kanai-Azuma M, Yoda T, Ogawa-Goto K, Iseki S: Heterozygous mutation of the splicing factor Sf3b4 affects development of the axial skeleton and forebrain in mouse. Developmental Dynamics. 2020.01; ( PubMed , DOI )

Doshida Y, Sano H, Iwabuchi S, Aigaki T, Yoshida M, Hashimoto S, Ishigami A: Age-associated changes in the transcriptomes of non-cultured adipose-derived stem cells from young and old mice assessed via single-cell transcriptome analysis. PloS one. 2020; 15 (11): e0242171. ( PubMed , DOI )

Takeru Yamauchi, Kei Takasawa, Takahiro Kamiya, Shizuka Kirino, Maki Gau, Kento Inoue, Akihiro Hoshino, Kenichi Kashimada, Hirokazu Kanegane, Tomohiro Morio: Hematopoietic stem cell transplantation recovers insulin deficiency in type 1 diabetes mellitus associated with IPEX syndrome. Pediatr Diabetes. 2019.11; 20 (7): 1035-1040. ( PubMed , DOI )

Nishi H., Inoue R., Osaka M., Inoue T., Yoshida M., Nangaku M.: Neutrophil interferon-induced, double-stranded RNA-activated protein kinase (EIF2AK2) mediates vascular adhesion and transmigration in non-viral inflammatory disease EUROPEAN JOURNAL OF IMMUNOLOGY. 2019.10; 49 582.

Kyaw Thiha, Yoichi Mashimo, Hiroyuki Suzuki, Hiromichi Hamada, Akira Hata, Toshiro Hara, Toshihiro Tanaka, Kaoru Ito, Yoshihiro Onouchi, : Correction to: Investigation of novel variations of ORAI1 gene and their association with Kawasaki disease. J Hum Genet. 2019.10; 64 (10): 1049. ( PubMed , DOI )

Yusuke Ebana, Yihan Sun, Xiaoxi Yang, Taiju Watanabe, Satoru Makita, Kouichi Ozaki, Toshihiro Tanaka, Hirokuni Arai, Tetsushi Furukawa: Pathway analysis with genome-wide association study (GWAS) data detected the association of atrial fibrillation with the mTOR signaling pathway. Int J Cardiol Heart Vasc. 2019.09; 24 100383. ( PubMed , DOI )

Yoshida H, Tada H, Ito K, Kishimoto Y, Yanai H, Okamura T, Ikewaki K, Inagaki K, Shoji T, Bujo H, Miida T, Yoshida M, Kuzuya M, Yamashita S: Reference Intervals of Serum Non-Cholesterol Sterols by Gender in Healthy Japanese Individuals. Journal of atherosclerosis and thrombosis. 2019.09; ( PubMed , DOI )

Chisato Shimizu, Jihoon Kim, Hariklia Eleftherohorinou, Victoria J Wright, Long T Hoang, Adriana H Tremoulet, Alessandra Franco, Martin L Hibberd, Atsushi Takahashi, Michiaki Kubo, Kaoru Ito, Toshihiro Tanaka, Yoshihiro Onouchi, Lachlan J M Coin, Michael Levin, Jane C Burns, Hiroko Shike, : HLA-C variants associated with amino acid substitutions in the peptide binding groove influence susceptibility to Kawasaki disease. Hum. Immunol.. 2019.09; 80 (9): 731-738. ( PubMed , DOI )

Takahashi Kenta, Oshima Noriko, Nakamura Reiko, Iwahara Yuki, Wakana Kimio, Yoshida Masayuki, Miyasaka Naoyuki: Detection of hereditary gynecologic cancer by screening and risk assessment using questionnaires in gynecological outpatient clinic(和訳中) The Journal of Obstetrics and Gynaecology Research. 2019.08; 45 (8): 1682. ( ichushi )

Arata Honda, Ryoma Tachibana, Kazuya Hamada, Kohtaro Morita, Naoaki Mizuno, Kento Morita, Masahide Asano: Efficient derivation of knock-out and knock-in rats using embryos obtained by in vitro fertilization. Sci Rep. 2019.08; 9 (1): 11571. ( PubMed , DOI )

Rie Saba, Keiko Kitajima, Lucille Rainbow, Silvia Engert, Mami Uemura, Hidekazu Ishida, Ioannis Kokkinopoulos, Yasunori Shintani, Shigeru Miyagawa, Yoshiakira Kanai, Masami Kanai-Azuma, Peter Koopman, Chikara Meno, John Kenny, Heiko Lickert, Yumiko Saga, Ken Suzuki, Yoshiki Sawa, Kenta Yashiro: Endocardium differentiation through Sox17 expression in endocardium precursor cells regulates heart development in mice. Sci Rep. 2019.08; 9 (1): 11953. ( PubMed , DOI )

Dewan Syed Masudur Rahman, Shiraishi Orie, Deushi Michiyo, Tani Mariko, Osaka Mizuko, Yoshida Masayuki: C5aによる好中球β2インテグリン活性化はPKCδの膜移行に関与する(C5a-induced β2 integrin activation in neutrophils involves membrane translocation of PKC δ) 日本動脈硬化学会総会プログラム・抄録集. 2019.07; 51回 2-P. ( ichushi )

Nakano Yujiro, Yoshimoto Takanobu, Watanabe Ryo, Murakami Masanori, Fukuda Tatsuya, Saito Kazutaka, Fujii Yasuhisa, Akashi Takumi, Tanaka Toshihiro, Yamada Tetsuya, Naruse Mitsuhide, Ogawa Yoshihiro: miRNA299 involvement in CYP11B2 expression in aldosterone-producing adenoma EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2019.07; 181 (1): 69-78. ( PubMed , DOI )

Sakurai Atsushi, Kinoshita Kosaku, Maeda Yukihiro, Homma Yosuke, Tahara Yoshio, Yonemoto Naohiro, Nagao Ken, Yaguchi Arino, Morimura Naoto, Inokuchi Sadaki, Masui Yoshihiro, Miura Kunihisa, Tsutsumi Haruhiko, Takuma Kiyotsugu, Atsushi Ishihara, Nakano Minoru, Tanaka Hiroshi, Ikegami Keiichi, Arai Takao, Yaguchi Arino, Kitamura Nobuya, Oda Shigeto, Kobayashi Kenji, Suda Takayuki, Ono Kazuyuki, Morimura Naoto, Furuya Ryosuke, Furuya Ryosuke, Koido Yuichi, Iwase Fumiaki, Nagao Ken, Kanesaka Shigeru, Okada Yasusei, Unemoto Kyoko, Sadahiro Tomohito, Iyanaga Masayuki, Muraoka Asaki, Hayashi Munehiro, Ishimatsu Shinichi, Miyake Yasufumi, Yokokawa Hideo, Koyama Yasuaki, Tsuchiya Asuka, Kashiyama Tetsuya, Hayashi Munetaka, Oshima Kiyohiro, Kiyota Kazuya, Hamabe Yuichi, Yokota Hiroyuki, Hori Shingo, Inaba Shin, Sakamoto Tetsuya, Harada Naoshige, Kimura Akio, Kanai Masayuki, Otomo Yasuhiro, Sugita Manabu, Kinoshita Kosaku, Sakurai Takatoshi, Kitano Mitsuhide, Matsuda Kiyoshi, Tanaka Kotaro, Yoshihara Katsunori, Yoh Kikuo, Suzuki Junichi, Toyoda Hiroshi, Mashiko Kunihiro, Shimizu Naoki, Muguruma Takashi, Shimada Tadanaga, Kobe Yoshiro, Shoko Tomohisa, Nakanishi Kazuya, Shiga Takashi, Yamamoto Takefumi, Sekine Kazuhiko, Izuka Shinichi: Confirmed cardiac output on emergency medical services arrival as confounding by indication: an observational study of prehospital airway management in patients with out-of-hospital cardiac arrest EMERGENCY MEDICINE JOURNAL. 2019.07; 36 (7): 410-+. ( DOI )

Naoaki Mizuno, Eiji Mizutani, Hideyuki Sato, Mariko Kasai, Hiromitsu Nakauchi, Tomoyuki Yamaguchi: CRISPR/Cas9 + AAV-mediated Intra-embryonic Gene Knocking in Mice. Bio Protoc. 2019.07; 9 (13): e3295. ( PubMed , DOI )

Zhou Dongjie, Suzuki Toru, Asami Maki, Perry Anthony C F: Caput Epididymidal Mouse Sperm Support Full Development. Dev Cell. 2019.07; 50 (1): 5-6. ( PubMed , DOI )

Hirate Yoshikazu, Nakano Yuki, Yoshida Tatsumi, Ito Hikaru, Uemura Mami, Kanai Yoshiakira, Kanai-Azuma Masami: 子宮内膜上皮移植に対する、TRECKに基づいたアプローチ法の確立(Establishment of a TRECK-based approach for replacement of uterine endometrial epithelium) Experimental Animals. 2019.07; 68 (Suppl.): S66. ( ichushi )

Takahashi Hitomi, Hirate Yoshikazu, Li Jinling, Ito Yoshiaki, Otsuka Chiho, Anezaki Mayumi, Asahara Hirosh, Chen-Tsai Ruby Yanru, Kanai-Azuma Masami: 試験管内授精マウス胚におけるTARGATTノックインシステムを用いた部位特異的遺伝子導入(Site-specific transgenesis using TARGATT knock-in system in in vitro fertilized mouse embryos) Experimental Animals. 2019.07; 68 (Suppl.): S219. ( ichushi )

Kyaw Thiha, Yoichi Mashimo, Hiroyuki Suzuki, Hiromichi Hamada, Akira Hata, Toshiro Hara, Toshihiro Tanaka, Kaoru Ito, Yoshihiro Onouchi, : Investigation of novel variations of ORAI1 gene and their association with Kawasaki disease. J. Hum. Genet.. 2019.06; 64 (6): 511-519. ( PubMed , DOI )

Kiichi Yamamoto, Kentaro Takahashi, Manabu Ato, Shiroh Iwanaga, Nobuo Ohta: Antimalarial activity of vitamin D3 (VD3) does not result from VD3-induced antimicrobial agents including nitric oxide or cathelicidin. Exp Parasitol. 2019.06; 201 67-77. ( PubMed , DOI )

Hirayama Atsushi, Yamashita Shizuya, Ruzza Andrea, Inomata Hyoe, Cyrille Marcoli, Lu Chen, Hamer Andrew W., Yoshida Masayuki, Kiyosue Arihiro, Teramoto Tamio: Long-Term Treatment With Evolocumab Among Japanese Patients - Final Report of the OSLER Open-Label Extension Studies CIRCULATION JOURNAL. 2019.05; 83 (5): 971-977. ( PubMed , DOI )

Nohara Atsushi, Otsubo Yoshihiko, Yanagi Koji, Yoshida Masayuki, Ikewaki Katsunori, Harada-Shiba Mariko, Jurecka Agnieszka: ホモ接合型家族性高コレステロール血症(HoFH)の日本人患者におけるロミタピドの安全性と有効性　AEGR-733-301長期延長試験の結果(Safety and Efficacy of Lomitapide in Japanese Patients with Homozygous Familial Hypercholesterolemia(HoFH): Results from the AEGR-733-301 Long-Term Extension Study) Journal of Atherosclerosis and Thrombosis. 2019.04; 26 (4): 368-377. ( ichushi )

Risa Nomura, Kenichi Kashimada, Hitomi Suzuki, Liang Zhao, Atsumi Tsuji-Hosokawa, Hideo Yagita, Masatoshi Takagi, Yoshiakira Kanai, Josephine Bowles, Peter Koopman, Masami Kanai-Azuma, Tomohiro Morio: Nr5a1 suppression during the murine fetal period optimizes ovarian development by fine-tuning Notch signaling. J. Cell. Sci.. 2019.04; 132 (8): ( PubMed , DOI )

Hirayama Atsushi, Yamashita Shizuya, Ruzza Andrea, Inomata Hyoe, Cyrille Marcoli, Hamer Andrew W., Yoshida Masayuki, Kiyosue Arihiro, Teramoto Tamio: 日本人患者におけるエボロクマブによる長期治療　OSLER非盲検延長試験の最終報告(Long-Term Treatment With Evolocumab Among Japanese Patients: Final Report of the OSLER Open-Label Extension Studies) Circulation Journal. 2019.04; 83 (5): 971-977. ( ichushi )

Yusuke Ebana, Tetsushi Furukawa: Networking analysis on superior vena cava arrhythmogenicity in atrial fibrillation. Int J Cardiol Heart Vasc. 2019.03; 22 150-153. ( PubMed , DOI )

Hirayama Atsushi, Yamashita Shizuya, Ruzza Andrea, Inomata Hyoe, Cyrille Marcoli, Hamer Andrew, Yoshida Masayuki, Kiyosue Arihiro, Teramoto Tamio: 日本人患者集団におけるevolocumabのOSLER非盲検延長試験の5年間の最終報告(Final 5-Year Report of the OSLER Open-Label Extension Studies of Evolocumab in the Japanese Patient Population) 日本循環器学会学術集会抄録集. 2019.03; 83回 LBCT2-4. ( ichushi )

Wataru Shimizu, Hisaki Makimoto, Kenichiro Yamagata, Tsukasa Kamakura, Mitsuru Wada, Koji Miyamoto, Yuko Inoue-Yamada, Hideo Okamura, Kohei Ishibashi, Takashi Noda, Satoshi Nagase, Aya Miyazaki, Heima Sakaguchi, Isao Shiraishi, Takeru Makiyama, Seiko Ohno, Hideki Itoh, Hiroshi Watanabe, Kenshi Hayashi, Masakazu Yamagishi, Hiroshi Morita, Masao Yoshinaga, Yoshiyasu Aizawa, Kengo Kusano, Yoshihiro Miyamoto, Shiro Kamakura, Satoshi Yasuda, Hisao Ogawa, Toshihiro Tanaka, Naotaka Sumitomo, Nobuhisa Hagiwara, Keiichi Fukuda, Satoshi Ogawa, Yoshifusa Aizawa, Naomasa Makita, Tohru Ohe, Minoru Horie, Takeshi Aiba: Association of Genetic and Clinical Aspects of Congenital Long QT Syndrome With Life-Threatening Arrhythmias in Japanese Patients. JAMA Cardiol. 2019.03; 4 (3): 246-254. ( PubMed , DOI )

Noriaki Yamada, Yoshihiro Asano, Masashi Fujita, Satoru Yamazaki, Atsushi Inanobe, Norio Matsuura, Hatasu Kobayashi, Seiko Ohno, Yusuke Ebana, Osamu Tsukamoto, Saki Ishino, Ayako Takuwa, Hidetaka Kioka, Toru Yamashita, Norio Hashimoto, Dimitar P Zankov, Akio Shimizu, Masanori Asakura, Hiroshi Asanuma, Hisakazu Kato, Yuya Nishida, Yohei Miyashita, Haruki Shinomiya, Nobu Naiki, Kenshi Hayashi, Takeru Makiyama, Hisakazu Ogita, Katsuyuki Miura, Hirotsugu Ueshima, Issei Komuro, Masakazu Yamagishi, Minoru Horie, Koichi Kawakami, Tetsushi Furukawa, Akio Koizumi, Yoshihisa Kurachi, Yasushi Sakata, Tetsuo Minamino, Masafumi Kitakaze, Seiji Takashima: Mutant KCNJ3 and KCNJ5 Potassium Channels as Novel Molecular Targets in Bradyarrhythmias and Atrial Fibrillation. Circulation. 2019.02; ( PubMed , DOI )

Takahashi Kenta, Oshima Noriko, Nakamura Reiko, Iwahara Yuki, Wakana Kimio, Yoshida Masayuki, Miyasaka Naoyuki: Detection of hereditary gynecologic cancer by screening and risk assessment using questionnaires in gynecological outpatient clinic(和訳中) 日本産科婦人科学会雑誌. 2019.02; 71 (臨増): S-196. ( ichushi )

Kameyama Noriko, Maruyama Chizuko, Kitagawa Fuyuha, Nishii Kazunobu, Uenomachi Kaori, Katayama Yayoi, Koga Hiromi, Chikamoto Naoko, Kuwata Yuko, Torigoe Junko, Arimoto Masako, Tokumaru Toshiaki, Ikewaki Katsunori, Nohara Atsushi, Otsubo Yoshihiko, Yanagi Koji, Yoshida Masayuki, Harada-Shiba Mariko: ホモ接合型家族性高コレステロール血症の日本人患者におけるロミタピド治療に対する56週間の低脂肪食摂取(Dietary Intake during 56 Weeks of a Low-Fat Diet for Lomitapide Treatment in Japanese Patients with Homozygous Familial Hypercholesterolemia) Journal of Atherosclerosis and Thrombosis. 2019.01; 26 (1): 72-83. ( ichushi )

Tamura Tomoyoshi, Suzuki Masaru, Hayashida Kei, Sasaki Junichi, Yonemoto Naohiro, Sakurai Atsushi, Tahara Yoshio, Nagao Ken, Yaguchi Arino, Morimura Naoto, Inokuchi Sadaki, Masui Yoshihiro, Miura Kunihisa, Tsutsumi Haruhiko, Takuma Kiyotsugu, Atsushi Ishihara, Nakano Minoru, Tanaka Hiroshi, Ikegami Keiichi, Arai Takao, Yaguchi Arino, Kitamura Nobuya, Oda Shigeto, Kobayashi Kenji, Suda Takayuki, Ono Kazuyuki, Morimura Naoto, Furuya Ryosuke, Koido Yuichi, Iwase Fumiaki, Nagao Ken, Kanesaka Shigeru, Okada Yasusei, Unemoto Kyoko, Sada-hiro Tomohito, Iyanaga Masayuki, Muraoka Asaki, Hayashi Munehiro, Ishimatsu Shinichi, Miyake Yasufumi, Yokokawa Hideo, Koyama Yasuaki, Tsuchiya Asuka, Kashiyama Tetsuya, Hayashi Munetaka, Oshima Kiyohiro, Kiyota Kazuya, Hamabe Yuichi, Yokota Hiroyuki, Hori Shingo, Inaba Shin, Sakamoto Tetsuya, Harada Naoshige, Kimura Akio, Kanai Masayuki, Otomo Yasuhiro, Sugita Manabu, Kinoshita Kosaku, Sakurai Takatoshi, Kitano Mitsuhide, Matsuda Kiyoshi, Tanaka Kotaro, Yoshihara Katsunori, Yoh Kikuo, Suzuki Junichi, Toyoda Hiroshi, Mashiko Kunihiro, Shimizu Naoki, Muguruma Takashi, Shimada Tadanaga, Kobe Yoshiro, Shoko Tomohisa, Nakanishi Kazuya, Shiga Takashi, Yamamoto Takefumi, Sekine Kazuhiko, Izuka Shinichi: Renal Function and Outcome of Out-of-Hospital Cardiac Arrest - Multicenter Prospective Study (SOS-KANTO 2012 Study) - CIRCULATION JOURNAL. 2019.01; 83 (1): 139-+. ( DOI )

Kameyama Noriko, Maruyama Chizuko, Kitagawa Fuyuha, Nishii Kazunobu, Uenomachi Kaori, Katayama Yayoi, Koga Hiromi, Chikamoto Naoko, Kuwata Yuko, Torigoe Junko, Arimoto Masako, Tokumaru Toshiaki, Ikewaki Katsunori, Nohara Atsushi, Otsubo Yoshihiko, Yanagi Koji, Yoshida Masayuki, Harada-Shiba Mariko: Dietary Intake during 56 Weeks of a Low-Fat Diet for Lomitapide Treatment in Japanese Patients with Homozygous Familial Hypercholesterolemia JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS. 2019; 26 (1): 72-83. ( PubMed , DOI )

Miura K, Harikae K, Nakaguch M, Imaimatsu K, Hiramatsu R, Tomita A, Hirate Y, Kanai-Azuma M, Kurohmaru M, Ogura A, Kanai Y: Molecular and genetic characterization of partial masculinization in embryonic ovaries grafted into male nude mice. PLoS ONE. 2019; 14 (3): e0212367. ( PubMed , DOI )

Nohara Atsushi, Otsubo Yoshihiko, Yanagi Koji, Yoshida Masayuki, Ikewaki Katsunori, Harada-Shiba Mariko, Jurecka Agnieszka: Safety and Efficacy of Lomitapide in Japanese Patients with Homozygous Familial Hypercholesterolemia (HoFH): Results from the AEGR-733-301 Long-Term Extension Study JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS. 2019; 26 (4): 368-377. ( PubMed , DOI )

Kamijo Y, Ishii H, Yamamoto T, Kobayashi K, Asano H, Miake S, Kanda E, Urata H, Yoshida M: Potential Impact on Lipoprotein Subfractions in Type 2 Diabetes. Clinical medicine insights. Endocrinology and diabetes. 2019; 12 1179551419866811. ( PubMed , DOI )

Miyake H, Yamada S, Fujii Y, Sawai H, Arimori N, Yamanouchi Y, Ozasa Y, Kanai M, Sago H, Sekizawa A, Takada F, Masuzaki H, Matsubara Y, Hirahara F, Kugu K: Correction: Nationwide survey for current clinical status of amniocentesis and maternal serum marker test in Japan. Journal of human genetics. 2018.11; 63 (11): 1195. ( PubMed , DOI )

Naoaki Mizuno, Eiji Mizutani, Hideyuki Sato, Mariko Kasai, Aki Ogawa, Fabian Suchy, Tomoyuki Yamaguchi, Hiromitsu Nakauchi: Intra-embryo Gene Cassette Knockin by CRISPR/Cas9-Mediated Genome Editing with Adeno-Associated Viral Vector. iScience. 2018.11; 9 286-297. ( PubMed , DOI )

Kawashima Saki, Funakoshi Tomoko, Sato Yasunori, Saito Norikatsu, Ohsawa Hajime, Kurita Katsumi, Nagata Kisaburo, Yoshida Masayuki, Ishigami Akihito: Protective effect of pre- and post-vitamin C treatments on UVB-irradiation-induced skin damage SCIENTIFIC REPORTS. 2018.11; 8 (1): 16199. ( PubMed , DOI )

Warr Nick, May Joel, Teboul Lydia, Suzuki Toru, Asami Maki, Perry Anthony C F, Wells Sara, Greenfield Andy: Characterisation and use of a functional Gadd45g bacterial artificial chromosome. Sci Rep. 2018.11; 8 (1): 17318. ( PubMed , DOI )

Sanae Hamanaka, Ayumi Umino, Hideyuki Sato, Tomonari Hayama, Ayaka Yanagida, Naoaki Mizuno, Toshihiro Kobayashi, Mariko Kasai, Fabian Patrik Suchy, Satoshi Yamazaki, Hideki Masaki, Tomoyuki Yamaguchi, Hiromitsu Nakauchi: Generation of Vascular Endothelial Cells and Hematopoietic Cells by Blastocyst Complementation. Stem Cell Reports. 2018.10; 11 (4): 988-997. ( PubMed , DOI )

Tomoyuki Yamaguchi, Hideyuki Sato, Toshihiro Kobayashi, Megumi Kato-Itoh, Teppei Goto, Hiromasa Hara, Naoaki Mizuno, Ayaka Yanagida, Ayumi Umino, Sanae Hamanaka, Fabian Suchy, Hideki Masaki, Yasunori Ota, Masumi Hirabayashi, Hiromitsu Nakauchi: An interspecies barrier to tetraploid complementation and chimera formation. Sci Rep. 2018.10; 8 (1): 15289. ( PubMed , DOI )

Gang Li, Aditi Khandekar, Tiankai Yin, Stephanie C Hicks, Qiusha Guo, Kentaro Takahashi, Catherine E Lipovsky, Brittany D Brumback, Praveen K Rao, Carla J Weinheimer, Stacey L Rentschler: Differential Wnt-mediated programming and arrhythmogenesis in right versus left ventricles. J Mol Cell Cardiol. 2018.10; 123 92-107. ( PubMed , DOI )

Bloss Jeffrey D., Nohara Atsushi, Otsubo Yoshihiko, Yanagi Koji, Yoshida Masayuki, Ikewaki Katsunori, Harada-Shiba Mariko, Jurecka Agnieszka: ホモ接合性家族性高コレステロール血症(HoFH)の日本人患者におけるlomitapideの安全性と有効性(Safety and efficacy of lomitapide in Japanese patients with Homozygous Familial Hypercholesterolemia(HoFH)) 日本心臓病学会学術集会抄録. 2018.09; 66回 P-026. ( ichushi )

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El Rouby N, McDonough CW, Gong Y, McClure LA, Mitchell BD, Horenstein RB, Talbert RL, Crawford DC; eMERGE network, Gitzendanner MA, Takahashi A, Tanaka T, Kubo M, Pepine CJ, Cooper-DeHoff RM, Benavente OR, Shuldiner AR, Johnson JA.: Genome-wide association analysis of common genetic variants of resistant hypertension. Pharmacogenomics J. 2018.09; ( DOI )

Igarashi H, Uemura M, Hiramatsu R, Hiramatsu R, Segami S, Pattarapanawan M, Hirate Y, Yoshimura Y, Hashimoto H, Higashiyama H, Sumitomo H, Kurohmaru M, Saijoh Y, Suemizu H, Kanai-Azuma M, Kanai Y: Sox17 is essential for proper formation of the marginal zone of extraembryonic endoderm adjacent to a developing mouse placental disk. Biol. Reprod. 2018.09; 99 (3): 578-589. ( PubMed , DOI )

Kitamura Kazutaka, Sato Kayoko, Sawabe Motoji, Yoshida Masayuki, Hagiwara Nobuhisa: P-Selectin Glycoprotein Ligand-1 (PSGL-1) Expressing CD4 T Cells Contribute Plaque Instability in Acute Coronary Syndrome CIRCULATION JOURNAL. 2018.08; 82 (8): 2128-+. ( PubMed , DOI )

Tani Mariko, Kamata Yuko, Deushi Michiyo, Osaka Mizuko, Yoshida Masayuki: 7-Ketocholesterol enhances leukocyte adhesion to endothelial cells via p38MAPK pathway PLOS ONE. 2018.07; 13 (7): e0200499. ( PubMed , DOI )

Kitamura Kazutaka, Sato Kayoko, Sawabe Motoji, Yoshida Masayuki, Hagiwara Nobuhisa: P-selectin glycoprotein ligand-1(PSGL-1)発現CD4 T細胞は急性冠動脈症候群におけるプラーク不安定性の一因となる(P-Selectin Glycoprotein Ligand-1(PSGL-1) Expressing CD4 T Cells Contribute Plaque Instability in Acute Coronary Syndrome) Circulation Journal. 2018.07; 82 (8): 2128-2135. ( ichushi )

Suzuki Toru, Asami Maki, Patel Sanjay G, Luk Louis Y P, Tsai Yu-Hsuan, Perry Anthony C F: Switchable genome editing via genetic code expansion. Sci Rep. 2018.07; 8 (1): 10051. ( PubMed , DOI )

Kamijo Yuka, Kanda Eiichiro, Horiuchi Hayato, Kounoue Noriyuki, Ono Keisuke, Maeda Keizo, Yanai Akane, Honda Kazuya, Tsujimoto Ryuji, Yanagi Mai, Ishibashi Yoshitaka, Yoshida Masayuki: 血液透析患者における動静脈瘻の血流音解析による血圧の連続モニタリング(Continuous monitoring of blood pressure by analyzing the blood flow sound of arteriovenous fistula in hemodialysis patients) Clinical and Experimental Nephrology. 2018.06; 22 (3): 677-683. ( ichushi )

Yoshida Masayuki, Osaka Mizuko: POTENTIAL ROLE OF NEUTROPHIL-MEDIATED VASCULAR INFLAMMATION AND NET FORMATION IN ATHEROSCLEROSIS ATHEROSCLEROSIS SUPPLEMENTS. 2018.06; 32 107.

Asami Masahiko, Tanabe Kengo, Ito Shunsuke, Yoshida Eri, Aoki Jiro, Tanimoto Shuzou, Horiuchi Yu, Yoshida Masayuki: 血液透析患者における冠動脈プラークに対するインドキシル硫酸の影響(Impact of Indoxyl Sulfate on Coronary Plaques in Patients on Hemodialysis) International Heart Journal. 2018.05; 59 (3): 489-496. ( ichushi )

Asami Masahiko, Tanabe Kengo, Ito Shunsuke, Yoshida Eri, Aoki Jiro, Tanimoto Shuzou, Horiuchi Yu, Yoshida Masayuki: Impact of Indoxyl Sulfate on Coronary Plaques in Patients on Hemodialysis INTERNATIONAL HEART JOURNAL. 2018.05; 59 (3): 489-496. ( PubMed , DOI )

Yoshimura T, Watanabe T, Kuramochi-Miyagawa S, Takemoto N, Shiromoto Y, Kudo A, Kanai-Azuma M, Tashiro F, Miyazaki S, Katanaya A, Chuma S, Miyazaki J: Mouse GTSF1 is an essential factor for secondary piRNA biogenesis. EMBO Rep. 2018.04; 19 (4): e42054. ( PubMed , DOI )

Saito K, Nobuhisa I, Harada K, Takahashi S, Anani M, Lickert H, Kanai-Azuma M, Kanai Y, Taga T: Maintenance of hematopoietic stem and progenitor cells in fetal intra-aortic hematopoietic clusters by the Sox17-Notch1-Hes1 axis. Exp. Cell Res. 2018.04; 365 (1): 145-155. ( PubMed , DOI )

Lee J, Matsuzawa A, Shiura H, Sutani A, Ishino F: Preferable in vitro condition for maintaining faithful DNA methylation imprinting in mouse embryonic stem cells. Genes to cells : devoted to molecular & cellular mechanisms. 2018.03; 23 (3): 146-160. ( PubMed , DOI )

鶴 裕美, 大坂 瑞子, 吉田 雅幸: 高脂肪食誘発性の血管の炎症における補体系D因子の潜在的役割(Potential Role of Complement Factor D in High-fat Diet-induced Vascular Inflammation) 日本循環器学会学術集会抄録集. 2018.03; 82回 PJ035-2. ( ichushi )

Yu Natsume, Kasumi Oaku, Kentaro Takahashi, Wakana Nakamura, Ai Oono, Satomi Hamada, Masahiro Yamazoe, Kensuke Ihara, Takeshi Sasaki, Masahiko Goya, Kenzo Hirao, Tetsushi Furukawa, Tetsuo Sasano: Combined Analysis of Human and Experimental Murine Samples Identified Novel Circulating MicroRNAs as Biomarkers for Atrial Fibrillation. Circulation Journal. 2018.03; 82 965-973. ( PubMed , DOI )

Hirata J, Hirota T, Ozeki T, Kanai M, Sudo T, Tanaka T, Hizawa N, Nakagawa H, Sato S, Mushiroda T, Saeki H, Tamari M, Okada Y.: Variants at HLA-A, HLA-C, and HLA-DQB1 Confer Risk of Psoriasis Vulgaris in Japanese. J Invest Dermatol. 2018.03; 138 (3): 542-548. ( DOI )

Ihara Kensuke, Sugiyama Koji, Takahashi Kentaro, Yamazoe Masahiro, Sasano Tetsuo, Furukawa Tetsushi: Electrophysiological Assessment of Murine Atria with High-Resolution Optical Mapping JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2018.02; (132): ( PubMed , DOI )

Higashiyama H, Uemura M, Igarashi H, Kurohmaru M, Kanai-Azuma M and Kanai Y: Anatomy and development of the extrahepatic biliary system in mouse and rat: a perspective on the evolutionary loss of the gallbladder. J. Anat. 2018.01; 232 (1): 134-145. ( PubMed , DOI )

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Kamijo Yuka, Kanda Eiichiro, Ishibashi Yoshitaka, Yoshida Masayuki: SARCOPENIA AND FRAILTY IN PD: IMPACT ON MORTALITY, MALNUTRITION, AND INFLAMMATION PERITONEAL DIALYSIS INTERNATIONAL. 2018; 38 (6): 447-454. ( PubMed , DOI )

Ebana Yusuke, Nitta Junichi, Takahashi Yoshihide, Miyazaki Shinsuke, Suzuki Masahito, Liu Lian, Hirao Kenzo, Kanda Eiichiro, Isobe Mitsuaki, Furukawa Tetsushi: Association of the Clinical and Genetic Factors With Superior Vena Cava Arrhythmogenicity in Atrial Fibrillation Circulation Journal. 2017.12; 82 (1): 71-77. ( ichushi )

Takahashi Sayako, Terui-Kohbata Hiroko, Ebana Yusuke, Yoshida Masayuki: Analysis of the Present Recognition Toward a Central IRB (cIRB) System in Japanese Medical Schools JOURNAL OF EMPIRICAL RESEARCH ON HUMAN RESEARCH ETHICS. 2017.12; 12 (5): 394-395.

Kenji Yoshioka, Shunsuke Kuroda, Kentaro Takahashi, Tetsuo Sasano, Tetsushi Furukawa, Akihiko Matsumura: Calcification of joints and arteries with novel NT5E mutations with involvement of upper extremity arteries. Vasc Med. 2017.12; 22 (6): 541-543. ( PubMed , DOI )

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Yusuke Ebana, Junichi Nitta, Yoshihide Takahashi, Shinsuke Miyazaki, Masahito Suzuki, Lian Liu, Kenzo Hirao, Eiichiro Kanda, Mitsuaki Isobe, Tetsushi Furukawa: Association of the Clinical and Genetic Factors With Superior Vena Cava Arrhythmogenicity in Atrial Fibrillation. Circ. J.. 2017.12; 82 (1): 71-77. ( PubMed , DOI )

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Ohigashi Hirokazu, Tamura Natsuko, Ebana Yusuke, Harigai Masayoshi, Maejima Yasuhiro, Ashikaga Takashi, Isobe Mitsuaki: Effects of immunosuppressive and biological agents on refractory Takayasu arteritis patients unresponsive to glucocorticoid treatment Journal of Cardiology. 2017.06; 69 (5-6): 774-778. ( ichushi )

T Sudo, Y Okada, K Ozaki, K Urayama, M Kanai, H Kobayashi, M Gokyu, Y Izumi, T Tanaka: Association of NOD2 Mutations with Aggressive Periodontitis. J. Dent. Res.. 2017.06; 22034517715432. ( PubMed , DOI )

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Yusuke Watanabe, Kota Y Miyasaka, Atsushi Kubo, Yasuyuki S Kida, Osamu Nakagawa, Yoshikazu Hirate, Hiroshi Sasaki, Toshihiko Ogura: Notch and Hippo signaling converge on Strawberry Notch 1 (Sbno1) to synergistically activate Cdx2 during specification of the trophectoderm. Scientific Reports. 2017.04; 7 46135. ( PubMed , DOI )

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Ebana Yusuke: Impact of Clinical and Genetic Factors on Superior Vena Cava Arrhythmogenicity in Atrial Fibrillation Japanese Circulation Society Scientific Meeting Abstracts. 2017.03; 81 OJ-114. ( ichushi )

Moe Kitazawa, Masaru Tamura, Tomoko Kaneko-Ishino, Fumitoshi Ishino: Severe damage to the placental fetal capillary network causes mid- to late fetal lethality and reduction in placental size in Peg11/Rtl1 KO mice. Genes Cells. 2017.02; 22 (2): 174-188. ( PubMed , DOI )

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LifeLines Cohort Study, Eoin P Brennan, Murim Choi, Zari Dastani, Alexander W Drong, Per Eriksson, Anders Franco-Cereceda, Jesper R Gådin, Ali G Gharavi, Michael E Goddard, Robert E Handsaker, Jinyan Huang, Fredrik Karpe, Sekar Kathiresan, Sarah Keildson, Krzysztof Kiryluk, Michiaki Kubo, Jong-Young Lee, Liming Liang, Richard P Lifton, Baoshan Ma, Steven A McCarroll, Amy J McKnight, Josine L Min, Miriam F Moffatt, Grant W Montgomery, Joanne M Murabito, George Nicholson, Dale R Nyholt, Yukinori Okada, John R B Perry, Rajkumar Dorajoo, Eva Reinmaa, Rany M Salem, Niina Sandholm, Robert A Scott, Lisette Stolk, Atsushi Takahashi, Toshihiro Tanaka, Ferdinand M Van't Hooft, Anna A E Vinkhuyzen, Harm-Jan Westra, Wei Zheng, Krina T Zondervan; ADIPOGen Consortium ; AGEN-BMI Working Group ; CARDIOGRAMplusC4D Consortium ; CKDGen Consortium ; GLGC ; ICBP; MAGIC Investigators ; MuTHER Consortium; MlGen Consortium ; PAGE Consortium ; ReproGen Consortium; GENIE Consortium; International Endogene Consortium , Andrew C Heath, Dominique Arveiler, Stephan J L Bakker, John Beilby, Richard N Bergman, John Blangero, Pascal Bovet, Harry Campbell, Mark J Caulfield, Giancarlo Cesana, Aravinda Chakravarti, Daniel I Chasman, Peter S Chines, Francis S Collins, Dana C Crawford, L Adrienne Cupples, Daniele Cusi, John Danesh, Ulf de Faire, Hester M den Ruijter, Anna F Dominiczak, Raimund Erbel, Jeanette Erdmann, Johan G Eriksson, Martin Farrall, Stephan B Felix, Ele Ferrannini, Jean Ferrières, Ian Ford, Nita G Forouhi, Terrence Forrester, Oscar H Franco, Ron T Gansevoort, Pablo V Gejman, Christian Gieger, Omri Gottesman, Vilmundur Gudnason, Ulf Gyllensten, Alistair S Hall, Tamara B Harris, Andrew T Hattersley, Andrew A Hicks, Lucia A Hindorff, Aroon D Hingorani, Albert Hofman, Georg Homuth, G Kees Hovingh, Steve E Humphries, Steven C Hunt, Elina Hyppönen, Thomas Illig, Kevin B Jacobs, Marjo-Riitta Jarvelin, Karl-Heinz Jöckel, Berit Johansen, Pekka Jousilahti, J Wouter Jukema, Antti M Jula, Jaakko Kaprio, John J P Kastelein, Sirkka M Keinanen-Kiukaanniemi, Lambertus A Kiemeney, Paul Knekt, Jaspal S Kooner, Charles Kooperberg, Peter Kovacs, Aldi T Kraja, Meena Kumari, Johanna Kuusisto, Timo A Lakka, Claudia Langenberg, Loic Le Marchand, Terho Lehtimäki, Valeriya Lyssenko, Satu Männistö, André Marette, Tara C Matise, Colin A McKenzie, Barbara McKnight, Frans L Moll, Andrew D Morris, Andrew P Morris, Jeffrey C Murray, Mari Nelis, Claes Ohlsson, Albertine J Oldehinkel, Ken K Ong, Pamela A F Madden, Gerard Pasterkamp, John F Peden, Annette Peters, Dirkje S Postma, Peter P Pramstaller, Jackie F Price, Lu Qi, Olli T Raitakari, Tuomo Rankinen, D C Rao, Treva K Rice, Paul M Ridker, John D Rioux, Marylyn D Ritchie, Igor Rudan, Veikko Salomaa, Nilesh J Samani, Jouko Saramies, Mark A Sarzynski, Heribert Schunkert, Peter E H Schwarz, Peter Sever, Alan R Shuldiner, Juha Sinisalo, Ronald P Stolk, Konstantin Strauch, Anke Tönjes, David-Alexandre Trégouët, Angelo Tremblay, Elena Tremoli, Jarmo Virtamo, Marie-Claude Vohl, Uwe Völker, Gérard Waeber, Gonneke Willemsen, Jacqueline C Witteman, M Carola Zillikens, Linda S Adair, Philippe Amouyel, Folkert W Asselbergs, Themistocles L Assimes, Murielle Bochud, Bernhard O Boehm, Eric Boerwinkle, Stefan R Bornstein, Erwin P Bottinger, Claude Bouchard, Stéphane Cauchi, John C Chambers, Stephen J Chanock, Richard S Cooper, Paul I W de Bakker, George Dedoussis, Luigi Ferrucci, Paul W Franks, Philippe Froguel, Leif C Groop, Christopher A Haiman, Anders Hamsten, Jennie Hui, David J Hunter, Kristian Hveem, Robert C Kaplan, Mika Kivimaki, Diana Kuh, Markku Laakso, Yongmei Liu, Nicholas G Martin, Winfried März, Mads Melbye, Andres Metspalu, Susanne Moebus, Patricia B Munroe, Inger Njølstad, Ben A Oostra, Colin N A Palmer, Nancy L Pedersen, Markus Perola, Louis Pérusse, Ulrike Peters, Chris Power, Thomas Quertermous, Rainer Rauramaa, Fernando Rivadeneira, Timo E Saaristo, Danish Saleheen, Naveed Sattar, Eric E Schadt, David Schlessinger, P Eline Slagboom, Harold Snieder, Tim D Spector, Unnur Thorsteinsdottir, Michael Stumvoll, Jaakko Tuomilehto, André G Uitterlinden, Matti Uusitupa, Pim van der Harst, Mark Walker, Henri Wallaschofski, Nicholas J Wareham, Hugh Watkins, David R Weir, H-Erich Wichmann, James F Wilson, Pieter Zanen, Ingrid B Borecki, Panos Deloukas, Caroline S Fox, Iris M Heid, Jeffrey R O'Connell, David P Strachan, Kari Stefansson, Cornelia M van Duijn, Gonçalo R Abecasis, Lude Franke, Timothy M Frayling, Mark I McCarthy, Peter M Visscher, André Scherag, Cristen J Willer, Michael Boehnke, Karen L Mohlke, Cecilia M Lindgren, Jacques S Beckmann, Inês Barroso, Kari E North, Erik Ingelsson, Joel N Hirschhorn, Ruth J F Loos, Elizabeth K Speliotes: Genetic studies of body mass index yield new insights for obesity biology. 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Eiichiro Kanda, Masayuki Yoshida, Sei Sasaki: Applicability of fibroblast growth factor 23 for evaluation of risk of vertebral fracture and chronic kidney disease-mineral bone disease in elderly chronic kidney disease patients. BMC Nephrol. 2012; 13 122. ( PubMed , DOI )

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Matsui Takaaki, Thitamadee Siripong, Murata Tomoko, Kakinuma Hisaya, Nabetani Takuji, Hirabayashi Yoshio, Hirate Yoshikazu, Okamoto Hitoshi, Bessho Yasumasa: Canopy1, a positive feedback regulator of FGF signaling, controls progenitor cell clustering during Kupffer's vesicle organogenesis. Proc Natl Acad Sci U S A. 2011.06; 108 (24): 9881-9886. ( PubMed , DOI )

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Tetsumin Lee, Tsunekazu Kakuta, Taishi Yonetsu, Kentaro Takahashi, Ginga Yamamoto, Yoshito Iesaka, Hideomi Fujiwara, Mitsuaki Isobe: Assessment of echo-attenuated plaque by optical coherence tomography and its impact on post-procedural creatine kinase-myocardial band elevation in elective stent implantation. JACC Cardiovasc Interv. 2011.05; 4 (5): 483-491. ( PubMed , DOI )

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Yoshida M: Not sleeping well can damage your heart. Hypertens Res. 2010.06; 33 (6): 535-536. ( PubMed , DOI )

Oishi Y, Manabe I, Imai Y, Hara K, Horikoshi M, Fujiu K, Tanaka T, Aizawa T, Kadowaki T, Nagai R: Regulatory polymorphism in transcription factor KLF5 at the MEF2 element alters the response to angiotensin II and is associated with human hypertension. FASEB J. 2010.06; 24 (6): 1780-1788. ( PubMed , DOI )

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Ino J, Kojima C, Osaka M, Nitta K, Yoshida M: Dynamic observation of mechanically-injured mouse femoral artery reveals an antiinflammatory effect of renin inhibitor. Arterioscler Thromb Vasc Biol. 2009.11; 29 (11): 1858-1863. ( PubMed , DOI )

Nomura M, Ishii H, Kawakami A, Yoshida M: Inhibition of hepatic Niemann-Pick C1-like 1 improves hepatic insulin resistance. Am J Physiol Endocrinol Metab. 2009.11; 297 (5): E1030-8. ( PubMed , DOI )

Sermsathanasawadi N, Ishii H, Igarashi K, Miura M, Yoshida M, Inoue Y, Iwai T: Enhanced adhesion of early endothelial progenitor cells to radiation-induced senescence-like vascular endothelial cells in vitro. J Radiat Res. 2009.09; 50 (5): 469-475. ( PubMed )

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Onda M, Emi M, Nagai H, Nagahata T, Tsumagari K, Fujimoto T, Akiyama F, Sakamoto G, Makita M, Kasumi F, Miki Y, Tanaka T, Tsunoda T, Nakamura Y: Gene expression patterns as marker for 5-year postoperative prognosis of primary breast cancers. J Cancer Res Clin Oncol. 2004.09; 130 (9): 537-545. ( PubMed , DOI )

Miyashita Toshio, Yeo Sang-Yeob, Hirate Yoshikazu, Segawa Hiroshi, Wada Hironori, Little Melissa H, Yamada Toshiya, Takahashi Naoki, Okamoto Hitoshi: PlexinA4 is necessary as a downstream target of Islet2 to mediate Slit signaling for promotion of sensory axon branching. Development. 2004.08; 131 (15): 3705-3715. ( PubMed , DOI )

Tsunoda T, Lathrop GM, Sekine A, Yamada R, Takahashi A, Ohnishi Y, Tanaka T, Nakamura Y: Variation of gene-based SNPs and linkage disequilibrium patterns in the human genome. Hum Mol Genet. 2004.08; 13 (15): 1623-1632. ( PubMed , DOI )

Hiraoka M, Nitta N, Nagai M, Shimokado K, Yoshida M: MCP-1-induced enhancement of THP-1 adhesion to vascular endothelium was modulated by HMG-CoA reductase inhibitor through RhoA GTPase-, but not ERK1/2-dependent pathway. Life Sci. 2004.07; 75 (11): 1333-1341. ( PubMed , DOI )

Integrating ethics and science in the International HapMap Project. Nat Rev Genet. 2004.06; 5 (6): 467-475. ( PubMed , DOI )

Toshimitsu Fuse, Yoshiakira Kanai, Masami Kanai-Azuma, Misao Suzuki, Kazuhiro Nakamura, Hisashi Mori, Yoshihiro Hayashi, Masayoshi Mishina: Conditional activation of RhoA suppresses the epithelial to mesenchymal transition at the primitive streak during mouse gastrulation. Biochem. Biophys. Res. Commun. 2004.06; 318 (3): 665-672. ( PubMed , DOI )

Ozaki K, Inoue K, Sato H, Iida A, Ohnishi Y, Sekine A, Sato H, Odashiro K, Nobuyoshi M, Hori M, Nakamura Y, Tanaka T: Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro. Nature. 2004.05; 429 (6987): 72-75. ( PubMed , DOI )

Nagahata T, Onda M, Emi M, Nagai H, Tsumagari K, Fujimoto T, Hirano A, Sato T, Nishikawa K, Akiyama F, Sakamoto G, Kasumi F, Miki Y, Tanaka T, Tsunoda T: Expression profiling to predict postoperative prognosis for estrogen receptor-negative breast cancers by analysis of 25,344 genes on a cDNA microarray. Cancer Sci. 2004.03; 95 (3): 218-225. ( PubMed )

Miki H, Lee J, Inoue K, Ogonuki N, Noguchi Y, Mochida K, Kohda T, Nagashima H, Ishino F, Ogura A: Microinsemination with first-wave round spermatids from immature male mice. The Journal of reproduction and development. 2004.02; 50 (1): 131-7. ( PubMed )

Okamoto Hitoshi, Hirate Yoshikazu, Ando Hideki: Systematic identification of factors in zebrafish regulating the early midbrain and cerebellar development by odered differential display and caged mRNA technology. Front Biosci. 2004.01; 9 93-99. ( PubMed )

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Bai CX, Takahashi K, Masumiya H, Sawanobori T, Furukawa T: Nitric oxide-dependent modulation of the delayed rectifier K+ current and the L-type Ca2+ current by ginsenoside Re, an ingredient of Panax ginseng, in guinea-pig cardiomyocytes Br J Pharmacol. 2004; 142 (3): 567-575. ( PubMed , DOI )

Sasaki Y, Mita H, Toyota M, Ishida S, Morimoto I, Yamashita T, Tanaka T, Imai K, Nakamura Y, Tokino T: Identification of the interleukin 4 receptor alpha gene as a direct target for p73. Cancer Res. 2003.12; 63 (23): 8145-8152. ( PubMed )

The International HapMap Project. Nature. 2003.12; 426 (6968): 789-796. ( PubMed , DOI )

Fujiyama S, Amano K, Uehira K, Yoshida M, Nishiwaki Y, Nozawa Y, Jin D, Takai S, Miyazaki M, Egashira K, Imada T, Iwasaka T, Matsubara H: Bone marrow monocyte lineage cells adhere on injured endothelium in a monocyte chemoattractant protein-1-dependent manner and accelerate reendothelialization as endothelial progenitor cells. Circ Res. 2003.11; 93 (10): 980-989. ( PubMed , DOI )

Onai Y, Suzuki J, Nishiwaki Y, Gotoh R, Berens K, Dixon R, Yoshida M, Ito H, Isobe M: Blockade of cell adhesion by a small molecule selectin antagonist attenuates myocardial ischemia/reperfusion injury. Eur J Pharmacol. 2003.11; 481 (2-3): 217-225. ( PubMed )

Toriumi Y, Hiraoka M, Watanabe M, Yoshida M: Pioglitazone reduces monocyte adhesion to vascular endothelium under flow by modulating RhoA GTPase and focal adhesion kinase. FEBS Lett. 2003.10; 553 (3): 419-422. ( PubMed )

Hiramatsu R, Kanai Y, Mizukami T, Ishii M, Matoba S, Kanai-Azuma M, Kurohmaru M, Kawakami H, Hayashi Y: Regionally distinct potencies of mouse XY genital ridge to initiate testis differentiation dependent on anteroposterior axis. Dev Dyn. 2003.10; 228 (2): 247-253. ( PubMed , DOI )

Nishiwaki Y, Yokota T, Hiraoka M, Miyagishi M, Taira K, Isobe M, Mizusawa H, Yoshida M: Introduction of short interfering RNA to silence endogenous E-selectin in vascular endothelium leads to successful inhibition of leukocyte adhesion. Biochem Biophys Res Commun. 2003.10; 310 (4): 1062-1066. ( PubMed )

Masaharu Kotani, Youichi Tajima, Taka Osanai, Atsushi Irie, Ken Iwatsuki, Masami Kanai-Azuma, Masato Imada, Hiroko Kato, Hiroshi Shitara, Hideo Kubo, Hitoshi Sakuraba: Complementary DNA cloning and characterization of RANDAM-2, a type I membrane molecule specifically expressed on glutamatergic neuronal cells in the mouse cerebrum. J. Neurosci. Res. 2003.09; 73 (5): 603-613. ( PubMed , DOI )

Yu T, Morita I, Shimokado K, Iwai T, Yoshida M: Amlodipine modulates THP-1 cell adhesion to vascular endothelium via inhibition of protein kinase C signal transduction. Hypertension. 2003.09; 42 (3): 329-334. ( PubMed , DOI )

Patrick P L Tam, Masami Kanai-Azuma, Yoshiakira Kanai: Early endoderm development in vertebrates: lineage differentiation and morphogenetic function. Curr. Opin. Genet. Dev. 2003.08; 13 (4): 393-400. ( PubMed )

Kuniko Nakano, Masami Kanai-Azuma, Yoshiakira Kanai, Kenji Moriyama, Kazumori Yazaki, Yoshihiro Hayashi, Naomi Kitamura: Cofilin phosphorylation and actin polymerization by NRK/NESK, a member of the germinal center kinase family. Exp. Cell Res. 2003.07; 287 (2): 219-227. ( PubMed )

Hirate Yoshikazu, Okamoto Hitoshi, Yamasu Kyo: Structure of the zebrafish fasciclin I-related extracellular matrix protein (betaig-h3) and its characteristic expression during embryogenesis. Gene Expr Patterns. 2003.06; 3 (3): 331-336. ( PubMed )

Yoshida M, Takano Y, Sasaoka T, Izumi T, Kimura A: E-selectin polymorphism associated with myocardial infarction causes enhanced leukocyte-endothelial interactions under flow conditions. Arterioscler Thromb Vasc Biol. 2003.05; 23 (5): 783-788. ( PubMed , DOI )

Watanabe G, Nishimori H, Irifune H, Sasaki Y, Ishida S, Zembutsu H, Tanaka T, Kawaguchi S, Wada T, Hata J, Kusakabe M, Yoshida K, Nakamura Y, Tokino T: Induction of tenascin-C by tumor-specific EWS-ETS fusion genes. Genes Chromosomes Cancer. 2003.03; 36 (3): 224-232. ( PubMed , DOI )

Tsukada S, Iwai M, Nishiu J, Itoh M, Tomoike H, Horiuchi M, Nakamura Y, Tanaka T: Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor. Circulation. 2003.01; 107 (2): 313-319. ( PubMed )

Iida A, Ozaki K, Ohnishi Y, Tanaka T, Nakamura Y: Identification of 46 novel SNPs in the 130-kb region containing a myocardial infarction susceptibility gene on chromosomal band 6p21. J Hum Genet. 2003; 48 (9): 476-479. ( PubMed , DOI )

Yoshida M: Potential role of statins in inflammation and atherosclerosis. J Atheroscler Thromb. 2003; 10 (3): 140-144. ( PubMed )

Obara W, Iida A, Suzuki Y, Tanaka T, Akiyama F, Maeda S, Ohnishi Y, Yamada R, Tsunoda T, Takei T, Ito K, Honda K, Uchida K, Tsuchiya K, Yumura W, Ujiie T, Nagane Y, Nitta K, Miyano S, Narita I, Gejyo F, Nihei H, Fujioka T, Nakamura Y: Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients. J Hum Genet. 2003; 48 (6): 293-299. ( PubMed , DOI )

Iida A, Tanaka T, Nakamura Y: High-density SNP map of human ITR, a gene associated with vascular remodeling. J Hum Genet. 2003; 48 (4): 170-172. ( PubMed , DOI )

Ozaki K, Ohnishi Y, Iida A, Sekine A, Yamada R, Tsunoda T, Sato H, Sato H, Hori M, Nakamura Y, Tanaka T: Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction. Nat Genet. 2002.12; 32 (4): 650-654. ( PubMed , DOI )

Takashi Noma, Yoshiakira Kanai, Masami Kanai-Azuma, Maki Ishii, Masahiko Fujisawa, Masamichi Kurohmaru, Hayato Kawakami, Stephen A Wood, Yoshihiro Hayashi: Stage- and sex-dependent expressions of Usp9x, an X-linked mouse ortholog of Drosophila Fat facets, during gonadal development and oogenesis in mice. Mech. Dev. 2002.12; 119 Suppl 1 S91-S95. ( PubMed )

Takashi Noma, Yoshiakira Kanai, Masami Kanai-Azuma, Maki Ishii, Masahiko Fujisawa, Masamichi Kurohmaru, Hayato Kawakami, Stephen A Wood, Yoshihiro Hayashi: Stage- and sex-dependent expressions of Usp9x, an X-linked mouse ortholog of Drosophila Fat facets, during gonadal development and oogenesis in mice. Gene Expr. Patterns. 2002.11; 2 (1-2): 87-91. ( PubMed )

Nishimori H, Sasaki Y, Yoshida K, Irifune H, Zembutsu H, Tanaka T, Aoyama T, Hosaka T, Kawaguchi S, Wada T, Hata J, Toguchida J, Nakamura Y, Tokino T: The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors. Oncogene. 2002.11; 21 (54): 8302-8309. ( PubMed , DOI )

Ishiguro H, Shimokawa T, Tsunoda T, Tanaka T, Fujii Y, Nakamura Y, Furukawa Y: Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas. Oncogene. 2002.09; 21 (41): 6387-6394. ( PubMed , DOI )

Kawakami A, Tanaka A, Nakajima K, Shimokado K, Yoshida M: Atorvastatin attenuates remnant lipoprotein-induced monocyte adhesion to vascular endothelium under flow conditions. Circ Res. 2002.08; 91 (3): 263-271. ( PubMed )

Inoue K, Matsuda K, Itoh M, Kawaguchi H, Tomoike H, Aoyagi T, Nagai R, Hori M, Nakamura Y, Tanaka T: Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5. Hum Mol Genet. 2002.07; 11 (15): 1775-1784. ( PubMed )

Masami Kanai-Azuma, Yoshiakira Kanai, Jacqueline M Gad, Youichi Tajima, Choji Taya, Masamichi Kurohmaru, Yutaka Sanai, Hiromichi Yonekawa, Kazumori Yazaki, Patrick P L Tam, Yoshihiro Hayashi: Depletion of definitive gut endoderm in Sox17-null mutant mice. Development. 2002.05; 129 (10): 2367-2379. ( PubMed )

Lee J, Inoue K, Ono R, Ogonuki N, Kohda T, Kaneko-Ishino T, Ogura A, Ishino F: Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells. Development (Cambridge, England). 2002.04; 129 (8): 1807-17. ( PubMed )

Takei T, Iida A, Nitta K, Tanaka T, Ohnishi Y, Yamada R, Maeda S, Tsunoda T, Takeoka S, Ito K, Honda K, Uchida K, Tsuchiya K, Suzuki Y, Fujioka T, Ujiie T, Nagane Y, Miyano S, Narita I, Gejyo F, Nihei H, Nakamura Y: Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy. Am J Hum Genet. 2002.03; 70 (3): 781-786. ( PubMed , DOI )

Inoue K, Kohda T, Lee J, Ogonuki N, Mochida K, Noguchi Y, Tanemura K, Kaneko-Ishino T, Ishino F, Ogura A: Faithful expression of imprinted genes in cloned mice. Science (New York, N.Y.). 2002.01; 295 (5553): 297. ( PubMed , DOI )

Hirakawa M, Tanaka T, Hashimoto Y, Kuroda M, Takagi T, Nakamura Y: JSNP: a database of common gene variations in the Japanese population. Nucleic Acids Res. 2002.01; 30 (1): 158-162. ( PubMed )

Sasaki Y, Ishida S, Morimoto I, Yamashita T, Kojima T, Kihara C, Tanaka T, Imai K, Nakamura Y, Tokino T: The p53 family member genes are involved in the Notch signal pathway. J Biol Chem. 2002.01; 277 (1): 719-724. ( PubMed , DOI )

Iwasa H, Kurabayashi M, Nagai R, Nakamura Y, Tanaka T: Twenty single-nucleotide polymorphisms in four genes encoding cardiac ion channels. J Hum Genet. 2002; 47 (4): 208-212. ( PubMed , DOI )

Akiyama F, Tanaka T, Yamada R, Ohnishi Y, Tsunoda T, Maeda S, Takei T, Obara W, Ito K, Honda K, Uchida K, Tsuchiya K, Nitta K, Yumura W, Nihei H, Ujiie T, Nagane Y, Miyano S, Suzuki Y, Fujioka T, Narita I, Gejyo F, Nakamura Y: Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy. J Hum Genet. 2002; 47 (10): 532-538. ( PubMed , DOI )

Haga H, Yamada R, Ohnishi Y, Nakamura Y, Tanaka T: Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190,562 genetic variations in the human genome. Single-nucleotide polymorphism. J Hum Genet. 2002; 47 (11): 605-610. ( PubMed , DOI )

Pantaleon M, Kanai-Azuma M, Mattick JS, Kaibuchi K, Kaye PL, Wood SA: FAM deubiquitylating enzyme is essential for preimplantation mouse embryo development. Mech Dev. 2001.12; 109 (2): 151-160. ( PubMed )

Fujita M, Furukawa Y, Tsunoda T, Tanaka T, Ogawa M, Nakamura Y: Up-regulation of the ectodermal-neural cortex 1 (ENC1) gene, a downstream target of the beta-catenin/T-cell factor complex, in colorectal carcinomas. Cancer Res. 2001.11; 61 (21): 7722-7726. ( PubMed )

Lin YM, Ono K, Satoh S, Ishiguro H, Fujita M, Miwa N, Tanaka T, Tsunoda T, Yang KC, Nakamura Y, Furukawa Y: Identification of AF17 as a downstream gene of the beta-catenin/T-cell factor pathway and its involvement in colorectal carcinogenesis. Cancer Res. 2001.09; 61 (17): 6345-6349. ( PubMed )

Kihara C, Tsunoda T, Tanaka T, Yamana H, Furukawa Y, Ono K, Kitahara O, Zembutsu H, Yanagawa R, Hirata K, Takagi T, Nakamura Y: Prediction of sensitivity of esophageal tumors to adjuvant chemotherapy by cDNA microarray analysis of gene-expression profiles. Cancer Res. 2001.09; 61 (17): 6474-6479. ( PubMed )

Y Hirate, M Mieda, T Harada, K Yamasu, H Okamoto: Identification of ephrin-A3 and novel genes specific to the midbrain-MHB in embryonic zebrafish by ordered differential display. Mech. Dev.. 2001.09; 107 (1-2): 83-96. ( PubMed )

Ishiguro H, Tsunoda T, Tanaka T, Fujii Y, Nakamura Y, Furukawa Y: Identification of AXUD1, a novel human gene induced by AXIN1 and its reduced expression in human carcinomas of the lung, liver, colon and kidney. Oncogene. 2001.08; 20 (36): 5062-5066. ( PubMed , DOI )

Yoshida M, Sawada T, Ishii H, Gerszten RE, Rosenzweig A, Gimbrone MA Jr, Yasukochi Y, Numano F: Hmg-CoA reductase inhibitor modulates monocyte-endothelial cell interaction under physiological flow conditions in vitro: involvement of Rho GTPase-dependent mechanism. Arterioscler Thromb Vasc Biol. 2001.07; 21 (7): 1165-1171. ( PubMed )

Suzuki Y, Tsunoda T, Sese J, Taira H, Mizushima-Sugano J, Hata H, Ota T, Isogai T, Tanaka T, Nakamura Y, Suyama A, Sakaki Y, Morishita S, Okubo K, Sugano S: Identification and characterization of the potential promoter regions of 1031 kinds of human genes. Genome Res. 2001.05; 11 (5): 677-684. ( PubMed , DOI )

Suzuki Y, Taira H, Tsunoda T, Mizushima-Sugano J, Sese J, Hata H, Ota T, Isogai T, Tanaka T, Morishita S, Okubo K, Sakaki Y, Nakamura Y, Suyama A, Sugano S: Diverse transcriptional initiation revealed by fine, large-scale mapping of mRNA start sites. EMBO Rep. 2001.05; 2 (5): 388-393. ( PubMed , DOI )

Kitahara O, Furukawa Y, Tanaka T, Kihara C, Ono K, Yanagawa R, Nita ME, Takagi T, Nakamura Y, Tsunoda T: Alterations of gene expression during colorectal carcinogenesis revealed by cDNA microarrays after laser-capture microdissection of tumor tissues and normal epithelia. Cancer Res. 2001.05; 61 (9): 3544-3549. ( PubMed )

Matsushima-Nishiu M, Unoki M, Ono K, Tsunoda T, Minaguchi T, Kuramoto H, Nishida M, Satoh T, Tanaka T, Nakamura Y: Growth and gene expression profile analyses of endometrial cancer cells expressing exogenous PTEN. Cancer Res. 2001.05; 61 (9): 3741-3749. ( PubMed )

H Segawa, T Miyashita, Y Hirate, S Higashijima, N Chino, K Uyemura, Y Kikuchi, H Okamoto: Functional repression of Islet-2 by disruption of complex with Ldb impairs peripheral axonal outgrowth in embryonic zebrafish. Neuron. 2001.05; 30 (2): 423-436. ( PubMed )

Yamada R, Tanaka T, Unoki M, Nagai T, Sawada T, Ohnishi Y, Tsunoda T, Yukioka M, Maeda A, Suzuki K, Tateishi H, Ochi T, Nakamura Y, Yamamoto K: Association between a single-nucleotide polymorphism in the promoter of the human interleukin-3 gene and rheumatoid arthritis in Japanese patients, and maximum-likelihood estimation of combinatorial effect that two genetic loci have on susceptibility to the disease. Am J Hum Genet. 2001.03; 68 (3): 674-685. ( PubMed , DOI )

Sekine-Aizawa Y, Hama E, Watanabe K, Tsubuki S, Kanai-Azuma M, Kanai Y, Arai H, Aizawa H, Iwata N, Saido TC: Matrix metalloproteinase (MMP) system in brain: identification and characterization of brain-specific MMP highly expressed in cerebellum. Eur J Neurosci. 2001.03; 13 (5): 935-948. ( PubMed )

Kunishima S, Kojima T, Matsushita T, Tanaka T, Tsurusawa M, Furukawa Y, Nakamura Y, Okamura T, Amemiya N, Nakayama T, Kamiya T, Saito H: Mutations in the NMMHC-A gene cause autosomal dominant macrothrombocytopenia with leukocyte inclusions (May-Hegglin anomaly/Sebastian syndrome). Blood. 2001.02; 97 (4): 1147-1149. ( PubMed )

Kato T, Satoh S, Okabe H, Kitahara O, Ono K, Kihara C, Tanaka T, Tsunoda T, Yamaoka Y, Nakamura Y, Furukawa Y: Isolation of a novel human gene, MARKL1, homologous to MARK3 and its involvement in hepatocellular carcinogenesis. Neoplasia. 2001.01; 3 (1): 4-9. ( PubMed , DOI )

Iida A, Ohnishi Y, Ozaki K, Ariji Y, Nakamura Y, Tanaka T: High-density single-nucleotide polymorphism (SNP) map in the 96-kb region containing the entire human DiGeorge syndrome critical region 2 (DGCR2) gene at 22q11.2. J Hum Genet. 2001; 46 (10): 604-608. ( PubMed , DOI )

Ohnishi Y, Tanaka T, Ozaki K, Yamada R, Suzuki H, Nakamura Y: A high-throughput SNP typing system for genome-wide association studies. J Hum Genet. 2001; 46 (8): 471-477. ( PubMed , DOI )

Iwasa H, Kurabayashi M, Nagai R, Nakamura Y, Tanaka T: Genetic variations in five genes involved in the excitement of cardiomyocytes. J Hum Genet. 2001; 46 (9): 549-552. ( PubMed , DOI )

Itoh T, Kikuchi K, Odagawa Y, Takata S, Yano K, Okada S, Haneda N, Ogawa S, Nakano O, Kawahara Y, Kasai H, Nakayama T, Fukutomi T, Sakurada H, Shimizu A, Yazaki Y, Nagai R, Nakamura Y, Tanaka T: Correlation of genetic etiology with response to beta-adrenergic blockade among symptomatic patients with familial long-QT syndrome. J Hum Genet. 2001; 46 (1): 38-40. ( PubMed , DOI )

Iwasa H, Kurabayashi M, Nagai R, Nakamura Y, Tanaka T: Multiple single-nucleotide polymorphisms (SNPs) in the Japanese population in six candidate genes for long QT syndrome. J Hum Genet. 2001; 46 (3): 158-162. ( PubMed , DOI )

Fukuda Y, Kurihara N, Imoto I, Yasui K, Yoshida M, Yanagihara K, Park JG, Nakamura Y, Inazawa J: CD44 is a potential target of amplification within the 11p13 amplicon detected in gastric cancer cell lines. Genes Chromosomes Cancer. 2000.12; 29 (4): 315-324. ( PubMed )

Ishii H, Yoshida M, Rosenzweig A, Gimbrone MA Jr, Yasukochi Y, Numano F: Adenoviral transduction of human E-selectin into isolated, perfused, rat aortic segments: an ex vivo model for studying leukocyte-endothelial interactions. J Leukoc Biol. 2000.11; 68 (5): 687-692. ( PubMed )

Ono K, Tanaka T, Tsunoda T, Kitahara O, Kihara C, Okamoto A, Ochiai K, Takagi T, Nakamura Y: Identification by cDNA microarray of genes involved in ovarian carcinogenesis. Cancer Res. 2000.09; 60 (18): 5007-5011. ( PubMed )

Kanai Y, Kanai-Azuma M, Tajima Y, Birk OS, Hayashi Y, Sanai Y: Identification of a stromal cell type characterized by the secretion of a soluble integrin-binding protein, MFG-E8, in mouse early gonadogenesis. Mech Dev. 2000.09; 96 (2): 223-227. ( PubMed )

Luscinskas FW, Gerszten RE, Garcia-Zepeda EA, Lim YC, Yoshida M, Ding HA, Gimbrone MA Jr, Luster AD, Rosenzweig A: C-C and C-X-C chemokines trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Ann N Y Acad Sci. 2000.05; 902 288-293. ( PubMed )

Yamauchi T, Tada M, Houkin K, Tanaka T, Nakamura Y, Kuroda S, Abe H, Inoue T, Ikezaki K, Matsushima T, Fukui M: Linkage of familial moyamoya disease (spontaneous occlusion of the circle of Willis) to chromosome 17q25. Stroke. 2000.04; 31 (4): 930-935. ( PubMed )

Yamada R, Tanaka T, Ohnishi Y, Suematsu K, Minami M, Seki T, Yukioka M, Maeda A, Murata N, Saiki O, Teshima R, Kudo O, Ishikawa K, Ueyosi A, Tateishi H, Inaba M, Goto H, Nishizawa Y, Tohma S, Ochi T, Yamamoto K, Nakamura Y: Identification of 142 single nucleotide polymorphisms in 41 candidate genes for rheumatoid arthritis in the Japanese population. Hum Genet. 2000.03; 106 (3): 293-297. ( PubMed )

Kanai-Azuma M, Mattick JS, Kaibuchi K, Wood SA: Co-localization of FAM and AF-6, the mammalian homologues of Drosophila faf and canoe, in mouse eye development. Mech Dev. 2000.03; 91 (1-2): 383-386. ( PubMed )

Ohnishi Y, Tanaka T, Yamada R, Suematsu K, Minami M, Fujii K, Hoki N, Kodama K, Nagata S, Hayashi T, Kinoshita N, Sato H, Sato H, Kuzuya T, Takeda H, Hori M, Nakamura Y: Identification of 187 single nucleotide polymorphisms (SNPs) among 41 candidate genes for ischemic heart disease in the Japanese population. Hum Genet. 2000.03; 106 (3): 288-292. ( PubMed )

Tsunoda T, Yamada R, Tanaka T, Ohnishi Y, Kamatani N: Environmental factor dependent maximum likelihood method for association study targeted to personalized medicine. Genome Inform Ser Workshop Genome Inform. 2000; 11 96-105. ( PubMed )

Nakajima T, Kurabayashi M, Ohyama Y, Kaneko Y, Furukawa T, Itoh T, Taniguchi Y, Tanaka T, Nakamura Y, Hiraoka M, Nagai R: Characterization of S818L mutation in HERG C-terminus in LQT2. Modification of activation-deactivation gating properties FEBS Lett. 2000; 481 (2): 197-203. ( PubMed )

Iwasa H, Itoh T, Nagai R, Nakamura Y, Tanaka T: Twenty single nucleotide polymorphisms (SNPs) and their allelic frequencies in four genes that are responsible for familial long QT syndrome in the Japanese population. J Hum Genet. 2000; 45 (3): 182-183. ( PubMed , DOI )

Seki T, Tanaka T, Nakamura Y: Genomic structure and multiple single-nucleotide polymorphisms (SNPs) of the thiopurine S-methyltransferase (TPMT) gene. J Hum Genet. 2000; 45 (5): 299-302. ( PubMed , DOI )

Kanai-Azuma M, Kanai Y, Okamoto M, Hayashi Y, Yonekawa H, Yazaki K: Nrk: a murine X-linked NIK (Nck-interacting kinase)-related kinase gene expressed in skeletal muscle. Mech Dev. 1999.12; 89 (1-2): 155-159. ( PubMed )

Taya S, Yamamoto T, Kanai-Azuma M, Wood SA, Kaibuchi K: The deubiquitinating enzyme Fam interacts with and stabilizes beta-catenin. Genes Cells. 1999.12; 4 (12): 757-767. ( PubMed )

Kunishima S, Kojima T, Tanaka T, Kamiya T, Ozawa K, Nakamura Y, Saito H: Mapping of a gene for May-Hegglin anomaly to chromosome 22q. Hum Genet. 1999.11; 105 (5): 379-383. ( PubMed )

Mikami M, Yasuda T, Terao A, Nakamura M, Ueno S, Tanabe H, Tanaka T, Onuma T, Goto Y, Kaneko S, Sano A: Localization of a gene for benign adult familial myoclonic epilepsy to chromosome 8q23.3-q24.1. Am J Hum Genet. 1999.09; 65 (3): 745-751. ( PubMed )

Y Hirate, K Tomita, S Yamamoto, K Kobari, I Uemura, K Yamasu, T Suyemitsu: Association of the sea urchin EGF-related peptide, EGIP-D, with fasciclin I-related ECM proteins from the sea urchin Anthocidaris crassispina. Dev. Growth Differ.. 1999.08; 41 (4): 483-494. ( PubMed )

Gerszten RE, Garcia-Zepeda EA, Lim YC, Yoshida M, Ding HA, Gimbrone MA Jr, Luster AD, Luscinskas FW, Rosenzweig A: MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature. 1999.04; 398 (6729): 718-723. ( PubMed , DOI )

Tsujikawa M, Kurahashi H, Tanaka T, Nishida K, Shimomura Y, Tano Y, Nakamura Y: Identification of the gene responsible for gelatinous drop-like corneal dystrophy. Nat Genet. 1999.04; 21 (4): 420-423. ( PubMed , DOI )

Nakajima T, Furukawa T, Hirano Y, Tanaka T, Sakurada H, Takahashi T, Nagai R, Itoh T, Katayama Y, Nakamura Y, Hiraoka M: Voltage-shift of the current activation in HERG S4 mutation (R534C) in LQT2 Cardiovasc Res. 1999; 44 (2): 283-293. ( PubMed )

Tsujikawa M, Kurahashi H, Tanaka T, Okada M, Yamamoto S, Maeda N, Watanabe H, Inoue Y, Kiridoshi A, Matsumoto K, Ohashi Y, Kinoshita S, Shimomura Y, Nakamura Y, Tano Y: Homozygosity mapping of a gene responsible for gelatinous drop-like corneal dystrophy to chromosome 1p. Am J Hum Genet. 1998.10; 63 (4): 1073-1077. ( PubMed , DOI )

Itoh T, Tanaka T, Nagai R, Kikuchi K, Ogawa S, Okada S, Yamagata S, Yano K, Yazaki Y, Nakamura Y: Genomic organization and mutational analysis of KVLQT1, a gene responsible for familial long QT syndrome. Hum Genet. 1998.09; 103 (3): 290-294. ( PubMed )

Nishiu J, Tanaka T, Nakamura Y: Identification of a novel gene (ECM2) encoding a putative extracellular matrix protein expressed predominantly in adipose and female-specific tissues and its chromosomal localization to 9q22.3. Genomics. 1998.09; 52 (3): 378-381. ( PubMed , DOI )

Taya S, Yamamoto T, Kano K, Kawano Y, Iwamatsu A, Tsuchiya T, Tanaka K, Kanai-Azuma M, Wood SA, Mattick JS, Kaibuchi K: The Ras target AF-6 is a substrate of the fam deubiquitinating enzyme. J Cell Biol. 1998.08; 142 (4): 1053-1062. ( PubMed )

Yoshida M, Szente BE, Kiely JM, Rosenzweig A, Gimbrone MA Jr: Phosphorylation of the cytoplasmic domain of E-selectin is regulated during leukocyte-endothelial adhesion. J Immunol. 1998.07; 161 (2): 933-941. ( PubMed )

Itoh T, Tanaka T, Nagai R, Kamiya T, Sawayama T, Nakayama T, Tomoike H, Sakurada H, Yazaki Y, Nakamura Y: Genomic organization and mutational analysis of HERG, a gene responsible for familial long QT syndrome. Hum Genet. 1998.04; 102 (4): 435-439. ( PubMed )

Nishiu J, Tanaka T, Nakamura Y: Isolation and chromosomal mapping of the human homolog of perilipin (PLIN), a rat adipose tissue-specific gene, by differential display method. Genomics. 1998.03; 48 (2): 254-257. ( PubMed , DOI )

Nakagawa H, Koyama K, Tanaka T, Miyoshi Y, Ando H, Baba S, Watatani M, Yasutomi M, Monden M, Nakamura Y: Localization of the gene responsible for Peutz-Jeghers syndrome within a 6-cM region of chromosome 19p13.3. Hum Genet. 1998.02; 102 (2): 203-206. ( PubMed )

Yamane-Tanaka Y, Kogawa K, Tanaka T, Nakamura Y, Isomura M: Heterozygosities and allelic frequencies of 358 dinucleotide-repeat marker loci in the Japanese population. J Hum Genet. 1998; 43 (3): 165-168. ( PubMed , DOI )

Itoh M, Tsukada S, Orita T, Nishiu J, Tomoike H, Nakamura Y, Tanaka T: Identification by differential display of eight known genes induced during in vivo intimal hyperplasia. J Hum Genet. 1998; 43 (1): 9-13. ( PubMed , DOI )

Nakajima T, Furukawa T, Tanaka T, Katayama Y, Nagai R, Nakamura Y, Hiraoka M: Novel mechanism of HERG current suppression in LQT2: shift in voltage dependence of HERG inactivation Circ Res. 1998; 83 (4): 415-422. ( PubMed )

Y Fujita, Y Hirate, T Hiyama, K Yamasu, T Suyemitsu, K Ishihara: Purification of EGIP-D-binding protein from the embryos of the sea urchin Anthocidaris crassispina. Zool. Sci.. 1997.12; 14 (6): 931-934. ( PubMed )

Yoshida M, Gimbrone MA Jr: Novel roles for E-selectin in endothelial-leukocyte adhesion. Ann N Y Acad Sci. 1997.04; 811 493-497. ( PubMed )

Tanaka T, Nagai R, Tomoike H, Takata S, Yano K, Yabuta K, Haneda N, Nakano O, Shibata A, Sawayama T, Kasai H, Yazaki Y, Nakamura Y: Four novel KVLQT1 and four novel HERG mutations in familial long-QT syndrome. Circulation. 1997.02; 95 (3): 565-567. ( PubMed )

Kanai-Azuma M, Kanai Y, Matsuda H, Kurohmaru M, Tachi C, Yazaki K, Hayashi Y: Nerve growth factor promotes giant-cell transformation of mouse trophoblast cells in vitro. Biochem Biophys Res Commun. 1997.02; 231 (2): 309-315. ( PubMed , DOI )

Tanemura K, Kanai Y, Kanai-Azuma M, Kurohmaru M, Kuramoto K, Yazaki K, Hayashi Y: Reinitiation of spermatogonial mitotic differentiation in inactive old BDF1 mouse seminiferous tubules transplanted to W/Wv mouse testis. Biol Reprod. 1996.12; 55 (6): 1237-1242. ( PubMed )

Tanaka T, Ogiwara A, Uchiyama I, Takagi T, Yazaki Y, Nakamura Y: Construction of a normalized directionally cloned cDNA library from adult heart and analysis of 3040 clones by partial sequencing. Genomics. 1996.07; 35 (1): 231-235. ( PubMed , DOI )

Kanai Y, Kanai-Azuma M, Noce T, Saido TC, Shiroishi T, Hayashi Y, Yazaki K: Identification of two Sox17 messenger RNA isoforms, with and without the high mobility group box region, and their differential expression in mouse spermatogenesis. J Cell Biol. 1996.05; 133 (3): 667-681. ( PubMed )

Yoshida M, Westlin WF, Wang N, Ingber DE, Rosenzweig A, Resnick N, Gimbrone MA Jr: Leukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeleton. J Cell Biol. 1996.04; 133 (2): 445-455. ( PubMed )

Tanaka T, Inazawa J, Nakamura Y: Molecular cloning and mapping of a human cDNA for cytosolic malate dehydrogenase (MDH1). Genomics. 1996.02; 32 (1): 128-130. ( PubMed , DOI )

Tanaka T, Inazawa J, Nakamura Y: Molecular cloning of a human cDNA encoding putative cysteine protease (PRSC1) and its chromosome assignment to 14q32.1. Cytogenet Cell Genet. 1996; 74 (1-2): 120-123. ( PubMed )

Kanai Y, Kanai-Azuma M, Kurohmaru M, Yazaki K, Hayashi Y: Effects of extracellular matrix on differentiation of mouse fetal gonads in the absence of mesonephros in vitro. Microsc Res Tech. 1995.12; 32 (5): 437-448. ( PubMed , DOI )

Chatterjee A, Tanaka T, Parrish JE, Herman GE: Refined mapping of caltractin in human Xq28 and in the homologous region of the mouse X chromosome places the gene within the bare patches (Bpa) and striated (Str) critical regions. Mamm Genome. 1995.11; 6 (11): 802-804. ( PubMed )

Tanaka T, Okui K, Nakamura Y: Assignment of the human caltractin gene (CALT) to Xq28 by fluorescence in situ hybridization. Genomics. 1994.12; 24 (3): 609-610. ( PubMed )

Tanaka T, Nakahara K, Kato N, Imai T, Yamazaki T, Tomita H, Shimokawa H, Matsuhashi H, Sato N, Matsui M: Genetic linkage analyses of Romano-Ward syndrome (RWS) in 13 Japanese families. Hum Genet. 1994.10; 94 (4): 380-384. ( PubMed )

Yoshida M, Kimura A, Katsuragi K, Numano F, Sasazuki T: DNA typing of HLA-B gene in Takayasu's arteritis. Tissue Antigens. 1993.08; 42 (2): 87-90. ( PubMed )

Kanai-Azuma M, Kanai Y, Kurohmaru M, Sakai S, Hayashi Y: Insulin-like growth factor (IGF)-I stimulates proliferation and migration of mouse ectoplacental cone cells, while IGF-II transforms them into trophoblastic giant cells in vitro. Biol Reprod. 1993.02; 48 (2): 252-261. ( PubMed )

Yoshida M, Kimura A, Numano F, Sasazuki T: Polymerase-chain-reaction-based analysis of polymorphism in the HLA-B gene. Hum Immunol. 1992.08; 34 (4): 257-266. ( PubMed )

Kanai Y, Kawakami H, Kanai-Azuma M, Kurohmaru M, Hirano H, Hayashi Y: Changes in intracellular and cell surface localization of Le(x) epitope during germ cell differentiation in fetal mice. J Vet Med Sci. 1992.04; 54 (2): 297-303. ( PubMed )

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Yusuke Ebana: Establishment of Certified Research Ethics Committee Professionals in Japan Journal of New Remedies & Clinics. 2018.10; 67 (10): 1251-1253.

Hirate Y: Technological innovation in mouse developmental engeneering Biomedical gerontology. 2018.09; 42 (3): 31-36.

Kanai-Azuma M: Basic research and analysis of the cause of implantation disorders due to environmental factors. J Soc Wom Health Sci Res. 2018.02; 7 (1): 3-6.

Yusuke Ebana: Ethics required for clinical research Endocrinology, Diabetology & Metabolism. 2017.08; 45 (2): 86-90.

Yusuke Ebana: Ethics in Clinical Research Obstet. Gynecol.. 2016.10; 83 (10): 1119-1123. ( ichushi )

Kouichi Ozaki, Toshihiro Tanaka: [Molecular genetics of coronary artery diseases]. Nippon Rinsho. 2016.06; 74 Suppl 4 Pt 1 306-313. ( PubMed )

Yusuke Ebana, Tetsushi Furukawa: Atrial fibrillation associated genes identified through genome-wide screening analysis - A review from viewpoints of bioinformatics, basic science, and clinical study - CARDIOANGIOLOGY. 2015.04; 77 (4): 371-378. ( ichushi )

A case of von Hippel-Lindau disease with pancreatic cysts diagnosed by novel PCR-based genetic testing 2014.11; 347.

H Terui-Kohbata: Psychosocial and info-medical genetic studies of the ambiguous results of genetic testing for hereditary cancer predisposition syndrome. 2014.03;

H Terui-Kohbata, H Numabe, K Akagi: Psychological impact of the ambiguous results of genetic testing for cancer susceptibility: a systematic review. Japanese journal of genetic counseling. 2013.12; 34 (4): 147-160. ( ichushi )