バイオデータ科学研究部門

692  件  
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  1. DeepKINET: a deep generative model for estimating single-cell RNA splicing and degradation rates 2024.09; 25 (1): 229. ( DOI )

  2. Imai D, Numoto N, Tokiwa H, Kakuta H, Ito N: Structural basis for the full and partial agonist activities of retinoid X receptor α ligands with an iso-butoxy and an isopropyl group. Biochemical and biophysical research communications. 2024.08; 734 150617. ( PubMed , DOI )

  3. Yukine Ishibashi, Mitsuru Naito, Yusuke Watanuki, Mao Hori, Satomi Ogura, Kaori Taniwaki, Masaru Cho, Ryosuke Komiya, Yuki Mochida, Kanjiro Miyata: Size-Dependent Glioblastoma Targeting by Polymeric Nanoruler with Prolonged Blood Circulation. Bioconjug Chem. 2024.08; 35 (8): 1154-1159. ( PubMed , DOI )

  4. Izuka S, Umezawa N, Komai T, Sugimori Y, Kimura N, Mizoguchi F, Fujieda Y, Ninagawa K, Iwasaki T, Suzuki K, Takeuchi T, Ohmura K, Mimori T, Atsumi T, Kawakami E, Suzuki A, Kochi Y, Yamamoto K, Yasuda S, Okamura T, Ota M, Fujio K: The muscle tissue transcriptome of idiopathic inflammatory myopathy reflects the muscle damage process by monocytes and presence of skin lesions. Arthritis & rheumatology (Hoboken, N.J.). 2024.08; ( PubMed , DOI )

  5. [Koichiro Majima,Yasuhiro Kojima,Kodai Minoura,Ko Abe,Haruka Hirose,Teppei Shimamura]: LineageVAE: Reconstructing Historical Cell States and Transcriptomes toward Unobserved Progenitors. 2024.08; ( PubMed , DOI )

  6. Joachim F R Van Guyse, Saed Abbasi, Kazuko Toh, Zlata Nagorna, Junjie Li, Anjaneyulu Dirisala, Sabina Quader, Satoshi Uchida, Kazunori Kataoka: Facile Generation of Heterotelechelic Poly(2-Oxazoline)s Towards Accelerated Exploration of Poly(2-Oxazoline)-Based Nanomedicine. Angewandte Chemie International Edition . 2024.07; 63 (27): e202404972. ( PubMed , DOI )

  7. Morino-Koga S, Tsuruda M, Zhao X, Oshiro S, Yokomizo T, Yamane M, Tanigawa S, Miike K, Usuki S, Yasunaga KI, Nishinakamura R, Suda T, Ogawa M: Transition of signal requirement in hematopoietic stem cell development from hemogenic endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 2024.07; 121 (31): e2404193121. ( PubMed , DOI )

  8. Yoshida M, Hanazono Y, Numoto N, Nagao S, Yabuno S, Kitagawa Y, Sekiguchi H, Ito N, Azuma T, Oda M: Affinity-matured antibody with a disulfide bond in H-CDR3 loop. Archives of biochemistry and biophysics. 2024.06; 758 110068. ( PubMed , DOI )

  9. Fangqiao Zheng, Ruizhi Tian, Hongxu Lu, Xiao Liang, Muhammad Shafiq, Satoshi Uchida, Hangrong Chen, Ming Ma: Droplet Microfluidics Powered Hydrogel Microparticles for Stem Cell-Mediated Biomedical Applications. Small. 2024.06; e2401400. ( PubMed , DOI )

  10. Saed Abbasi, Miki Matsui-Masai, Fumihiko Yasui, Akimasa Hayashi, Theofilus A Tockary, Yuki Mochida, Shiro Akinaga, Michinori Kohara, Kazunori Kataoka, Satoshi Uchida: Carrier-free mRNA vaccine induces robust immunity against SARS-CoV-2 in mice and non-human primates without systemic reactogenicity. Molecular Therapy. 2024.05; 32 (5): 1266-1283. ( PubMed , DOI )

  11. Spatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis 2024.05; 103 105102. ( DOI )

  12. Akatsu C, Tsuneshige T, Numoto N, Long W, Uchiumi T, Kaneko Y, Asano M, Ito N, Tsubata T: CD72 is an inhibitory pattern recognition receptor that recognizes ribosomes and suppresses production of anti-ribosome autoantibody. Journal of autoimmunity. 2024.05; 146 103245. ( PubMed , DOI )

  13. Inamo J, Suzuki A, Ueda MT, Yamaguchi K, Nishida H, Suzuki K, Kaneko Y, Takeuchi T, Hatano H, Ishigaki K, Ishihama Y, Yamamoto K, Kochi Y: Long-read sequencing for 29 immune cell subsets reveals disease-linked isoforms. Nature communications. 2024.05; 15 (1): 4285. ( PubMed , DOI )

  14. Ono C, Kochi Y, Baba Y, Tanaka S: Humoral responses are enhanced by facilitating B cell viability by Fcrl5 overexpression in B cells. International immunology. 2024.05; ( PubMed , DOI )

  15. Omori S, Hanazono Y, Nishi H, Kinoshita K: The role of the STAS domain in SLC26A9 for chloride ion transporter function. Biophysical journal. 2024.05; 123 (12): 1751-1762. ( PubMed , DOI )

  16. Oka, A; Hadano, S; Ueda, MT; Nakagawa, S; Komaki, G; Ando, T: Rare CRHR2 and GRM8 variants identified as candidate factors associated with eating disorders in Japanese patients by whole exome sequencing HELIYON. 2024.04; 10 (8): e28643. ( PubMed , DOI )

  17. Pengwen Chen, Wenqian Yang, Yuki Mochida, Shangwei Li, Taehun Hong, Hiroaki Kinoh, Kazunori Kataoka, Horacio Cabral: Selective Intracellular Delivery of Antibodies in Cancer Cells with Nanocarriers Sensing Endo/Lysosomal Enzymatic Activity. Angewandte Chemie International Edition. 2024.04; 63 (14): e202317817. ( PubMed , DOI )

  18. [Yasuhiro Kojima,Yuko Arioka,Haruka Hirose,Shuto Hayashi,Yusuke Mizuno,Keiki Nagaharu,Hiroki Okumura,Masato Ishikawa,Kohshi Ohishi,Yutaka Suzuki,Norio Ozaki,Teppei Shimamura]: Inferring extrinsic factor-dependent single-cell transcriptome dynamics using a deep generative model 2024.04; ( DOI )

  19. Okunishi K, Kochi Y, Zhao M, Wang H, Nakagome K, Izumi T: Munc13-4 regulates asthma and obesity in mice by controlling functions of CD11c(+) antigen-presenting cells. Allergy. 2024.03; 79 (7): 1992-1995. ( PubMed , DOI )

  20. Fuseya Y, Kadoba K, Liu X, Suetsugu H, Iwasaki T, Ohmura K, Sumida T, Kochi Y, Morinobu A, Terao C, Iwai K: Attenuation of HOIL-1L ligase activity promotes systemic autoimmune disorders by augmenting linear ubiquitin signaling. JCI insight. 2024.02; 9 (3): ( PubMed , DOI )

  21. Single-cell colocalization analysis using a deep generative model 2024.02; 15 (2): 180-192.e7. ( DOI )

  22. Yoriyuki Konno, Keiya Uriu, Takayuki Chikata, Toru Takada, Jun-Ichi Kurita, Mahoko Takahashi Ueda, Saiful Islam, Benjy Jek Yang Tan, Jumpei Ito, Hirofumi Aso, Ryuichi Kumata, Carolyn Williamson, Shingo Iwami, Masafumi Takiguchi, Yoshifumi Nishimura, Eiji Morita, Yorifumi Satou, So Nakagawa, Yoshio Koyanagi, Kei Sato: Two-step evolution of HIV-1 budding system leading to pandemic in the human population. Cell Reports. 2024.02; 43 (2): 113697. ( PubMed , DOI )

  23. Miki Suzuki, Yuki Mochida, Mao Hori, Akimasa Hayashi, Kazuko Toh, Theofilus A. Tockary, Xueying Liu, Victor Marx, Hidetomo Yokoo, Kanjiro Miyata, Makoto Oba, Satoshi Uchida: Poly(ethylene Glycol) (PEG)–OligoRNA Hybridization to mRNA Enables Fine‐Tuned Polyplex PEGylation for Spleen‐Targeted mRNA Delivery Small Science. 2024.02; ( DOI )

  24. Lucas Mixich, Eger Boonstra, Keita Masuda, Shang-Wei Li, Yuki Nakashima, Fanlu Meng, Momoko Sakata, Tatsuro Goda, Satoshi Uchida, Horacio Cabral: Ionizable Polymeric Micelles with Phenylalanine Moieties Enhance Intracellular Delivery of Self-Replicating RNA for Long-Lasting Protein Expression In Vivo. Biomacromolecules. 2024.02; 25 (2): 1058-1067. ( PubMed , DOI )

  25. Hidetomo Yokoo, Anjaneyulu Dirisala, Satoshi Uchida, Makoto Oba: Oligosarcosine Conjugation of Arginine-Rich Peptides Improves the Intracellular Delivery of Peptide/pDNA Complexes. ACS Biomaterials Science & Engineering. 2024.02; 10 (2): 890-896. ( PubMed , DOI )

  26. Yum J, Aulia F, Kamiya K, Hori M, Qiao N, Kim BS, Naito M, Ogura S, Nagata T, Yokota T, Uchida S, Obika S, Kim HJ, Miyata K: Hydrophobicity Tuning of Cationic Polyaspartamide Derivatives for Enhanced Antisense Oligonucleotide Delivery. Bioconjugate chemistry. 2024.01; 35 (2): 125-131. ( PubMed , DOI )

  27. Yuki S Tateishi, Tamasa Araki, Satoru Kawai, Shuhei Koide, Yuko Umeki, Takashi Imai, Yumiko Saito-Nakano, Masaki Kikuchi, Atsushi Iwama, Hajime Hisaeda, Cevayir Coban, Takeshi Annoura: Histone H3.3 variant plays a critical role on zygote-to-oocyst development in malaria parasites. Parasitology International. 2024.01; ( PubMed , DOI )

  28. Yuki Mochida, Satoshi Uchida: mRNA vaccine designs for optimal adjuvanticity and delivery. RNA Biology. 2024.01; 21 (1): 1-27. ( PubMed , DOI )

  1. BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state. 2023.12; 14 (1): 8372. ( PubMed , DOI )

  2. Mwalilino L, Yamane M, Ishiguro KI, Usuki S, Endoh M, Niwa H: The role of Zfp352 in the regulation of transient expression of 2-cell specific genes in mouse embryonic stem cells. Genes to cells : devoted to molecular & cellular mechanisms. 2023.12; 28 (12): 831-844. ( PubMed , DOI )

  3. Ueda, MT: Retrotransposon-derived transcripts and their functions in immunity and disease GENES & GENETIC SYSTEMS. 2023.12; 98 (6): 305-319. ( PubMed , DOI )

  4. Shichen Chang, Satoru Torii, Jun Inamo, Kinya Ishikawa, Yuta Kochi, Shigeomi Shimizu: Uncovering the Localization and Function of a Novel Read-Through Transcript ' TOMM40-APOE' Cells. 2023.12; 13 (1): ( PubMed , DOI )

  5. Tsuyuzaki K, Ishii M, Nikaido I: Sctensor detects many-to-many cell-cell interactions from single cell RNA-sequencing data. BMC bioinformatics. 2023.11; 24 (1): 420. ( PubMed , DOI )

  6. Mengjiao Li, Tatsunori Nishimura, Yasuto Takeuchi, Tsunaki Hongu, Yuming Wang, Daisuke Shiokawa, Kang Wang, Haruka Hirose, Asako Sasahara, Masao Yano, Satoko Ishikawa, Masafumi Inokuchi, Tetsuo Ota, Masahiko Tanabe, Kei-Ichiro Tada, Tetsu Akiyama, Xi Cheng, Chia-Chi Liu, Toshinari Yamashita, Sumio Sugano, Yutaro Uchida, Tomoki Chiba, Hiroshi Asahara, Masahiro Nakagawa, Shinya Sato, Yohei Miyagi, Teppei Shimamura, Luis Augusto E Nagai, Akinori Kanai, Manami Katoh, Seitaro Nomura, Ryuichiro Nakato, Yutaka Suzuki, Arinobu Tojo, Dominic C Voon, Seishi Ogawa, Koji Okamoto, Theodoros Foukakis, Noriko Gotoh: FXYD3 functionally demarcates an ancestral breast cancer stem cell subpopulation with features of drug-tolerant persisters. J Clin Invest. 2023.11; 133 (22): ( PubMed , DOI )

  7. [Shiki Fujino,Norikatsu Miyoshi,Aya Ito,Rie Hayashi,Masayoshi Yasui,Chu Matsuda,Masayuki Ohue,Masafumi Horie,Shinichi Yachida,Jun Koseki,Teppei Shimamura,Tsuyoshi Hata,Takayuki Ogino,Hidekazu Takahashi,Mamoru Uemura,Tsunekazu Mizushima,Yuichiro Doki,Hidetoshi Eguchi]: Metastases and treatment-resistant lineages in patient-derived cancer cells of colorectal cancer 2023.11; 6 (1): 1191. ( PubMed , DOI )

  8. Yasuyuki Shima, Henrik Skibbe, Yohei Sasagawa, Noriko Fujimori, Yoshimi Iwayama, Ayako Isomura-Matoba, Minoru Yano, Takumi Ichikawa, Itoshi Nikaido, Nobutaka Hattori, Tadafumi Kato: Distinctiveness and continuity in transcriptome and connectivity in the anterior-posterior axis of the paraventricular nucleus of the thalamus Cell Reports. 2023.10; 42 (10): ( DOI )

  9. Masaki Kikuchi, Shohei Takase, Tsuyoshi Konuma, Kota Noritsugu, Saaya Sekine, Takahisa Ikegami, Akihiro Ito, Takashi Umehara: GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain. Proceedings of the National Academy of Sciences of the United States of America. 2023.10; 120 (43): e2304103120. ( PubMed , DOI )

  10. Shima, Y; Skibbe, H; Sasagawa, Y; Fujimori, N; Iwayama, Y; Isomura-Matoba, A; Yano, M; Ichikawa, T; Nikaido, I; Hattori, N; Kato, T: Distinctiveness and continuity in transcriptome and connectivity in the anterior-posterior axis of the paraventricular nucleus of the thalamus CELL REPORTS. 2023.10; 42 (10): 113309. ( PubMed , DOI )

  11. [Miki Kato,Keisuke Maeda,Ryuichi Nakahara,Haruka Hirose,Ayano Kondo,Sho Aki,Maki Sugaya,Sana Hibino,Miyuki Nishida,Manami Hasegawa,Hinano Morita,Ritsuko Ando,Rika Tsuchida,Minoru Yoshida,Tatsuhiko Kodama,Hideyuki Yanai,Teppei Shimamura,Tsuyoshi Osawa]: Acidic extracellular pH drives accumulation of N1-acetylspermidine and recruitment of protumor neutrophils PNAS nexus. 2023.10; 2 (10): pgad306. ( PubMed , DOI )

  12. [Ryuichi Nakahara,Sho Aki,Maki Sugaya,Haruka Hirose,Miki Kato,Keisuke Maeda,Daichi M Sakamoto,Yasuhiro Kojima,Miyuki Nishida,Ritsuko Ando,Masashi Muramatsu,Melvin Pan,Rika Tsuchida,Yoshihiro Matsumura,Hideyuki Yanai,Hiroshi Takano,Ryoji Yao,Shinsuke Sando,Masabumi Shibuya,Juro Sakai,Tatsuhiko Kodama,Hiroyasu Kidoya,Teppei Shimamura,Tsuyoshi Osawa]: Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth 2023.10; 42 (22): e114032. ( PubMed , DOI )

  13. Kobayashi Y, Niida A, Nagayama S, Saeki K, Haeno H, Takahashi KK, Hayashi S, Ozato Y, Saito H, Hasegawa T, Nakamura H, Tobo T, Kitagawa A, Sato K, Shimizu D, Hirata H, Hisamatsu Y, Toshima T, Yonemura Y, Masuda T, Mizuno S, Kawazu M, Kohsaka S, Ueno T, Mano H, Ishihara S, Uemura M, Mori M, Doki Y, Eguchi H, Oshima M, Suzuki Y, Shibata T, Mimori K: Subclonal accumulation of immune escape mechanisms in microsatellite instability-high colorectal cancers. British journal of cancer. 2023.10; 129 (7): 1105-1118. ( PubMed , DOI )

  14. Chisato Ono, Shinya Tanaka, Keiko Myouzen, Takeshi Iwasaki, Mahoko Ueda, Yoshinao Oda, Kazuhiko Yamamoto, Yuta Kochi, Yoshihiro Baba: Upregulated Fcrl5 disrupts B cell anergy causes autoimmune disease Frontiers in Immunology. 2023.09; 14 276014. ( DOI )

  15. Mahoko Takahashi Ueda: Retrotransposon-derived transcripts and their functions associated with immunity and disease Genes & Genetic Systems. 2023.09; in press

  16. Bekker GJ, Numoto N, Kawasaki M, Hayashi T, Yabuno S, Kozono Y, Shimizu T, Kozono H, Ito N, Oda M, Kamiya N: Elucidation of binding mechanism, affinity and complex structure between mWT1 tumor-associated antigen peptide and HLA-A*24:02. Protein Science. 2023.09; 32 (10): e4775. ( PubMed , DOI )

  17. Yuya Hanazono, Yu Hirano, Taro Tamada, Kunio Miki: Description of peptide bond planarity from high-resolution neutron crystallography Biophysics and Physicobiology. 2023.09; 20 (3): e200035.

  18. Satoshi Uchida, Chun Yin Jerry Lau, Makoto Oba, Kanjiro Miyata: Polyplex designs for improving the stability and safety of RNA therapeutics. Advanced Drug Delivery Reviews . 2023.08; 199 114972. ( PubMed , DOI )

  19. Ogura Nao, Sasagawa Yohei, Ito Tasuku, Tameshige Toshiaki, Kawai Satomi, Sano Masaki, Doll Yuki, Iwase Akira, Kawamura Ayako, Suzuki Takamasa, Nikaido Itoshi, Sugimoto Keiko, Ikeuchi Momoko: WUSCHEL-RELATED HOMEOBOX 13 suppresses de novo shoot regeneration via cell fate control of pluripotent callus SCIENCE ADVANCES. 2023.07; 9 (27): eadg6983. ( PubMed , DOI )

  20. Theofilus A Tockary, Saed Abbasi, Miki Matsui-Masai, Akimasa Hayashi, Naoto Yoshinaga, Eger Boonstra, Zheng Wang, Shigeto Fukushima, Kazunori Kataoka, Satoshi Uchida: Comb-structured mRNA vaccine tethered with short double-stranded RNA adjuvants maximizes cellular immunity for cancer treatment. Proc Natl Acad Sci U S A. 2023.07; 120 (29): e2214320120. ( PubMed , DOI )

  21. Mitsui Y, Suzuki T, Kuniyoshi K, Inamo J, Yamaguchi K, Komuro M, Watanabe J, Edamoto M, Li S, Kouno T, Oba S, Hosoya T, Masuhiro K, Naito Y, Koyama S, Sakaguchi N, Standley DM, Shin JW, Akira S, Yasuda S, Miyazaki Y, Kochi Y, Kumanogoh A, Okamoto T, Satoh T: Expression of the readthrough transcript CiDRE in alveolar macrophages boosts SARS-CoV-2 susceptibility and promotes COVID-19 severity. Immunity. 2023.07; 56 (8): 1939-1954.e12. ( PubMed , DOI )

  22. Masaki Kikuchi, Satoshi Morita, Masatoshi Wakamori, Shin Sato, Tomomi Uchikubo-Kamo, Takehiro Suzuki, Naoshi Dohmae, Mikako Shirouzu, Takashi Umehara: Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nature communications. 2023.07; 14 (1): 4103. ( PubMed , DOI )

  23. Nan Liu, Tsuyoshi Konuma, Rajal Sharma, Deyu Wang, Nan Zhao, Lingling Cao, Ying Ju, Di Liu, Shuai Wang, Almudena Bosch, Yifei Sun, Siwei Zhang, Donglei Ji, Satoru Nagatoishi, Noa Suzuki, Masaki Kikuchi, Masatoshi Wakamori, Chengcheng Zhao, Chunyan Ren, Thomas Jiachi Zhou, Yaoyao Xu, Jamel Meslamani, Shibo Fu, Takashi Umehara, Kouhei Tsumoto, Satoko Akashi, Lei Zeng, Robert G Roeder, Martin J Walsh, Qiang Zhang, Ming-Ming Zhou: Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin. Molecular cell. 2023.07; 83 (13): 2206-2221. ( PubMed , DOI )

  24. [So Takeuchi,Takuya Takeichi,Yoshinao Muro,Teppei Shimamura,Masashi Akiyama]: Plucked scalp hair follicle samples are useful RNA sources for mRNA analysis of most genodermatosis-associated genes 2023.07; 111 (2): 68-70. ( PubMed , DOI )

  25. [Ko Abe,Teppei Shimamura]: UNMF: a unified nonnegative matrix factorization for multi-dimensional omics data 2023.07; 24 (5): ( PubMed , DOI )

  26. Tsuyuzaki Koki, Yamamoto Kentaro, Toyoshima Yu, Sato Hirofumi, Kanamori Manami, Teramoto Takayuki, Ishihara Takeshi, Iino Yuichi, Nikaido Itoshi: WormTensor: a clustering method for time-series whole-brain activity data from C. elegans BMC BIOINFORMATICS. 2023.06; 24 (1): 254. ( PubMed , DOI )

  27. Hayashi Yasutaka, Nishimura Koutarou, Tanaka Atsushi, Inoue Daichi: 骨髄性悪性腫瘍における細胞外小胞を介した骨髄微小環境のリモデリング(Stem cell regulation and dynamics in myeloid malignancies: Extracellular vesicle-mediated remodeling of the bone marrow microenvironment in myeloid malignancies) International Journal of Hematology. 2023.06; 117 (6): 821-829. ( 医中誌 )

  28. Takada Hitomi, Sasagawa Yohei, Yoshimura Mika, Tanaka Kaori, Iwayama Yoshimi, Hayashi Tetsutaro, Isomura-Matoba Ayako, Nikaido Itoshi, Kurisaki Akira: Single-cell transcriptomics uncovers EGFR signaling-mediated gastric progenitor cell differentiation in stomach homeostasis NATURE COMMUNICATIONS. 2023.06; 14 (1): 3750. ( PubMed , DOI )

  29. Nao Otomo, Anas M Khanshour, Masaru Koido, Kazuki Takeda, Yukihide Momozawa, Michiaki Kubo, Yoichiro Kamatani, John A Herring, Yoji Ogura, Yohei Takahashi, Shohei Minami, Koki Uno, Noriaki Kawakami, Manabu Ito, Tatsuya Sato, Kei Watanabe, Takashi Kaito, Haruhisa Yanagida, Hiroshi Taneichi, Katsumi Harimaya, Yuki Taniguchi, Hideki Shigematsu, Takahiro Iida, Satoru Demura, Ryo Sugawara, Nobuyuki Fujita, Mitsuru Yagi, Eijiro Okada, Naobumi Hosogane, Katsuki Kono, Masaya Nakamura, Kazuhiro Chiba, Toshiaki Kotani, Tsuyoshi Sakuma, Tsutomu Akazawa, Teppei Suzuki, Kotaro Nishida, Kenichiro Kakutani, Taichi Tsuji, Hideki Sudo, Akira Iwata, Satoshi Inami, Carol A Wise, Yuta Kochi, Morio Matsumoto, Shiro Ikegawa, Kota Watanabe, Chikashi Terao: Evidence of causality of low body mass index on risk of adolescent idiopathic scoliosis: a Mendelian randomization study. Front Endocrinol (Lausanne). 2023.06; 14 1089414. ( PubMed , DOI )

  30. Debabrata Maiti, Hao Yu, Yuki Mochida, Seongyeon Won, Shinichi Yamashita, Mitsuru Naito, Kanjiro Miyata, Hyun Jin Kim: Terbium-Rose Bengal Coordination Nanocrystals-Induced ROS Production under Low-Dose X-rays in Cultured Cancer Cells for Photodynamic Therapy. ACS Applied Bio Materials. 2023.06; 6 (6): 2505-2513. ( DOI )

  31. Masahito Inagaki, Naoko Abe, Zhenmin Li, Yuko Nakashima, Susit Acharyya, Kazuya Ogawa, Daisuke Kawaguchi, Haruka Hiraoka, Ayaka Banno, Zheyu Meng, Mizuki Tada, Tatsuma Ishida, Pingxue Lyu, Kengo Kokubo, Hirotaka Murase, Fumitaka Hashiya, Yasuaki Kimura, Satoshi Uchida, Hiroshi Abe: Cap analogs with a hydrophobic photocleavable tag enable facile purification of fully capped mRNA with various cap structures. Nature Communications. 2023.05; 14 (1): 2657. ( PubMed , DOI )

  32. Topological data analysis of protein structure and inter/intra- molecular interaction changes attributable to amino acid mutations 2023.05; 21 2950-2959. ( DOI )

  33. Fujitani H, Eguchi H, Kochi Y, Arai T, Muramatsu M, Okazaki Y: Rare germline variants in pancreatic cancer and multiple primary cancers: an autopsy study. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP). 2023.05; 32 (3): 286-297. ( PubMed , DOI )

  34. Extracellular vesicle-mediated remodeling of the bone marrow microenvironment in myeloid malignancies. 2023.04; ( PubMed , DOI )

  35. Kitagawa A, Osawa T, Noda M, Kobayashi Y, Aki S, Nakano Y, Saito T, Shimizu D, Komatsu H, Sugaya M, Takahashi J, Kosai K, Takao S, Motomura Y, Sato K, Hu Q, Fujii A, Wakiyama H, Tobo T, Uchida H, Sugimachi K, Shibata K, Utsunomiya T, Kobayashi S, Ishii H, Hasegawa T, Masuda T, Matsui Y, Niida A, Soga T, Suzuki Y, Miyano S, Aburatani H, Doki Y, Eguchi H, Mori M, Nakayama KI, Shimamura T, Shibata T, Mimori K: Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma. British journal of cancer. 2023.04; 128 (12): 2206-2217. ( PubMed , DOI )

  36. nnTensor: An R package for non-negative matrix/tensor decomposition. 2023.04; ( DOI )

  37. Makoto Oba, Mika Shibuya, Yuto Yamaberi, Hidetomo Yokoo, Satoshi Uchida, Atsushi Ueda, Masakazu Tanaka: An Amphipathic Structure of a Dipropylglycine-Containing Helical Peptide with Sufficient Length Enables Safe and Effective Intracellular siRNA Delivery. Chemical and Pharmaceutical Bulletin. 2023.03; 71 (3): 250-256. ( PubMed , DOI )

  38. [Shiho Torii,Kwang Su Kim,Jun Koseki,Rigel Suzuki,Shoya Iwanami,Yasuhisa Fujita,Yong Dam Jeong,Jumpei Ito,Hiroyuki Asakura,Mami Nagashima,Kenji Sadamasu,Kazuhisa Yoshimura,Kei Sato,Yoshiharu Matsuura,Teppei Shimamura,Shingo Iwami,Takasuke Fukuhara]: Increased flexibility of the SARS-CoV-2 RNA-binding site causes resistance to remdesivir 2023.03; 19 (3): e1011231. ( PubMed , DOI )

  39. Spatial and single-cell transcriptomics decipher the cellular environment containing HLA-G+ cancer cells and SPP1+ macrophages in colorectal cancer. 2023.01; 42 (1): 111929. ( PubMed , DOI )

  40. [Jun Koseki,Haruka Hirose,Masamitsu Konno,Teppei Shimamura]: Theoretical Computational Analysis Predicts Interaction Changes Due to Differences of a Single Molecule in DNA 2023.01; 13 (1): 510. ( DOI )

  1. Hall D, Basu G, Ito N: Computational biophysics and structural biology of proteins-a Special Issue in honor of Prof. Haruki Nakamura's 70th birthday. Biophysical reviews. 2022.12; 14 (6): 1211-1222. ( PubMed , DOI )

  2. Bayesian statistical method for detecting structural and topological diversity in polymorphic proteins. 2022.11; 20 6519-6525. ( PubMed , DOI )

  3. Ishigaki K, Sakaue S, Terao C, Luo Y, Sonehara K, Yamaguchi K, Amariuta T, Too CL, Laufer VA, Scott IC, Viatte S, Takahashi M, Ohmura K, Murasawa A, Hashimoto M, Ito H, Hammoudeh M, Emadi SA, Masri BK, Halabi H, Badsha H, Uthman IW, Wu X, Lin L, Li T, Plant D, Barton A, Orozco G, Verstappen SMM, Bowes J, MacGregor AJ, Honda S, Koido M, Tomizuka K, Kamatani Y, Tanaka H, Tanaka E, Suzuki A, Maeda Y, Yamamoto K, Miyawaki S, Xie G, Zhang J, Amos CI, Keystone E, Wolbink G, van der Horst-Bruinsma I, Cui J, Liao KP, Carroll RJ, Lee HS, Bang SY, Siminovitch KA, de Vries N, Alfredsson L, Rantapää-Dahlqvist S, Karlson EW, Bae SC, Kimberly RP, Edberg JC, Mariette X, Huizinga T, Dieudé P, Schneider M, Kerick M, Denny JC, BioBank Japan Project, Matsuda K, Matsuo K, Mimori T, Matsuda F, Fujio K, Tanaka Y, Kumanogoh A, Traylor M, Lewis CM, Eyre S, Xu H, Saxena R, Arayssi T, Kochi Y, Ikari K, Harigai M, Gregersen PK, Yamamoto K, Louis Bridges S Jr, Padyukov L, Martin J, Klareskog L, Okada Y, Raychaudhuri S: Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis. Nature genetics. 2022.11; 54 (11): 1640-1651. ( PubMed , DOI )

  4. Nucleic Acid-triggered Tumoral Immunity Propagates pH-selective Therapeutic Antibodies through Tumor-driven Epitope Spreading. 2022.09; 114 (1): 321-338. ( PubMed , DOI )

  5. Yamaguchi K, Ishigaki K, Suzuki A, Tsuchida Y, Tsuchiya H, Sumitomo S, Nagafuchi Y, Miya F, Tsunoda T, Shoda H, Fujio K, Yamamoto K, Kochi Y: Splicing QTL analysis focusing on coding sequences reveals mechanisms for disease susceptibility loci. Nature communications. 2022.08; 13 (1): 4659. ( PubMed , DOI )

  6. Kato D, Mitsuhashi S, Miya F, Saitoh S, Okamoto N, Tsunoda T, Kochi Y: Utility of tissue-specific gene expression scores for gene prioritization in Mendelian diseases. Journal of human genetics. 2022.08; 67 (12): 739-742. ( PubMed , DOI )

  7. Masaki Kikuchi, Satoshi Morita, Mie Goto, Masatoshi Wakamori, Kazushige Katsura, Kazuharu Hanada, Mikako Shirouzu, Takashi Umehara: Elucidation of binding preferences of YEATS domains to site-specific acetylated nucleosome core particles. The Journal of biological chemistry. 2022.08; 298 (8): 102164. ( PubMed , DOI )

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  3. Tsuchida N, Hamada K, Shiina M, Kato M, Kobayashi Y, Tohyama J, Kimura K, Hoshino K, Ganesan V, Teik KW, Nakashima M, Mitsuhashi S, Mizuguchi T, Takata A, Miyake N, Saitsu H, Ogata K, Miyatake S, Matsumoto N: GRIN2D variants in three cases of developmental and epileptic encephalopathy. Clinical genetics. 2018.12; 94 (6): 538-547. ( PubMed , DOI )

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  5. Miyatake S, Schneeberger S, Koyama N, Yokochi K, Ohmura K, Shiina M, Mori H, Koshimizu E, Imagawa E, Uchiyama Y, Mitsuhashi S, Frith MC, Fujita A, Satoh M, Taguri M, Tomono Y, Takahashi K, Doi H, Takeuchi H, Nakashima M, Mizuguchi T, Takata A, Miyake N, Saitsu H, Tanaka F, Ogata K, Hennet T, Matsumoto N: Biallelic COLGALT1 variants are associated with cerebral small vessel disease. Annals of neurology. 2018.12; 84 (6): 843-853. ( PubMed , DOI )

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  51. Watanabe N, Kryukov K, Nakagawa S, Takeuchi JS, Takeshita M, Kirimura Y, Mitsuhashi S, Ishihara T, Aoki H, Inokuchi S, Imanishi T, Inoue S: Detection of pathogenic bacteria in the blood from sepsis patients using 16S rRNA gene amplicon sequencing analysis. PloS one. 2018; 13 (8): e0202049. ( PubMed , DOI )

  52. Nishino J, Kochi Y, Shigemizu D, Kato M, Ikari K, Ochi H, Noma H, Matsui K, Morizono T, Boroevich KA, Tsunoda T, Matsui S: Empirical Bayes Estimation of Semi-parametric Hierarchical Mixture Models for Unbiased Characterization of Polygenic Disease Architectures. Frontiers in genetics. 2018; 9 115. ( PubMed , DOI )

  53. Mori-Yoshimura M, Mitsuhashi S, Nakamura H, Komaki H, Goto K, Yonemoto N, Takeuchi F, Hayashi YK, Murata M, Takahashi Y, Nishino I, Takeda S, Kimura E: Characteristics of Japanese Patients with Becker Muscular Dystrophy and Intermediate Muscular Dystrophy in a Japanese National Registry of Muscular Dystrophy (Remudy): Heterogeneity and Clinical Variation. Journal of neuromuscular diseases. 2018; 5 (2): 193-203. ( PubMed , DOI )

  1. 森田 梨津子, 三千 典子, 林 哲太郎, 梅田 茉奈, 芳村 美佳, 二階堂 愛, 阿部 高也, 清成 寛, 古田 泰秀, 藤原 裕展: 毛包幹細胞の起源と誘導メカニズムの解明 生命科学系学会合同年次大会. 2017.12; 2017年度 [4P2T16-0817)].

  2. Terao C, Okada Y, Ikari K, Kochi Y, Suzuki A, Ohmura K, Matsuo K, Taniguchi A, Kubo M, Raychaudhuri S, Yamamoto K, Yamanaka H, Kamatani Y, Mimori T, Matsuda F: Genetic landscape of interactive effects of HLA-DRB1 alleles on susceptibility to ACPA(+) rheumatoid arthritis and ACPA levels in Japanese population. Journal of medical genetics. 2017.12; 54 (12): 853-858. ( PubMed , DOI )

  3. Naoto Yoshinaga, Takehiko Ishii, Mitsuru Naito, Taisuke Endo, Satoshi Uchida, Horacio Cabral, Kensuke Osada, Kazunori Kataoka: Polyplex micelles with phenylboronate/gluconamide cross-linking in the core exerting promoted gene transfection through spatiotemporal responsivity to intracellular pH and ATP concentration Journal of the American Chemical Society. 2017.11; 139 (51): 18567-18575. ( DOI )

  4. Mitsuhashi S, Nakagawa S, Takahashi Ueda M, Imanishi T, Frith MC, Mitsuhashi H: Nanopore-based single molecule sequencing of the D4Z4 array responsible for facioscapulohumeral muscular dystrophy. Scientific reports. 2017.11; 7 (1): 14789. ( PubMed , DOI )

  5. Haiyang Hu, Masahiro Uesaka, Song Guo, Kotaro Shimai, Tsai-Ming Lu, Fang Li, Satoko Fujimoto, Masato Ishikawa, Shiping Liu, Yohei Sasagawa, Guojie Zhang, Shigeru Kuratani, Jr-Kai Yu, Takehiro G. Kusakabe, Philipp Khaitovich, Naoki Irie: Constrained vertebrate evolution by pleiotropic genes NATURE ECOLOGY & EVOLUTION. 2017.11; 1 (11): 1722-1730. ( DOI )

  6. Ishiyama A, Sakai C, Matsushima Y, Noguchi S, Mitsuhashi S, Endo Y, Hayashi YK, Saito Y, Nakagawa E, Komaki H, Sugai K, Sasaki M, Sato N, Nonaka I, Goto YI, Nishino I: IBA57 mutations abrogate iron-sulfur cluster assembly leading to cavitating leukoencephalopathy. Neurology. Genetics. 2017.10; 3 (5): e184. ( PubMed , DOI )

  7. Okubo M, Minami N, Goto K, Goto Y, Noguchi S, Mitsuhashi S, Nishino I: Corrigendum: Genetic diagnosis of Duchenne/Becker muscular dystrophy using next-generation sequencing: validation analysis of DMD mutations. Journal of human genetics. 2017.10; 62 (10): 931-933. ( PubMed , DOI )

  8. Y Anraku, H Kuwahara, Y Fukusato, A Mizoguchi, T Ishii, K Nitta, Y Matsumoto, K Toh, K Miyata, S Uchida, K Nishina, K Osada, K Itaka, N Nishiyama, H Mizusawa, T Yamasoba, T Yokota, K Kataoka: Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain. Nat Commun. 2017.10; 8 (1): 1001. ( PubMed , DOI )

  9. Oka A, Asano Y, Hasegawa M, Fujimoto M, Ishikawa O, Kuwana M, Kawaguchi Y, Yamamoto T, Takahashi H, Goto D, Endo H, Jinnin M, Mano S, Hosomichi K, Mabuchi T, Ueda MT, Nakagawa S, Beck S, Bahram S, Takehara K, Sato S, Ihn H: RXRB Is an MHC-Encoded Susceptibility Gene Associated with Anti-Topoisomerase I Antibody-Positive Systemic Sclerosis. The Journal of investigative dermatology. 2017.09; 137 (9): 1878-1886. ( PubMed , DOI )

  10. Kazuki Miyano, Horacio Cabral, Yutaka Miura, Yu Matsumoto, Yuki Mochida, Hiroaki Kinoh, Caname Iwata, Osamu Nagano, Hideyuki Saya, Nobuhiro Nishiyama, Kazunori Kataoka, Tatsuya Yamasoba: cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells. Journal of Controlled Release. 2017.09; 261 275-286. ( DOI )

  11. Yuta Shinohara, Yohei M. Koyama, Maki Ukai-Tadenuma, Takatsugu Hirokawa, Masaki Kikuchi, Rikuhiro G. Yamada, Hideki Ukai, Hiroshi Fujishima, Takashi Umehara, Kazuki Tainaka, Hiroki R. Ueda: Temperature-Sensitive Substrate and Product Binding Underlie Temperature-Compensated Phosphorylation in the Clock. Molecular cell. 2017.09; 67 (5): 783-798. ( DOI )

  12. Satoshi Uchida, Naoto Yoshinaga, Kayoko Yanagihara, Eiji Yuba, Kazunori Kataoka, Keiji Itaka: Designing immunostimulatory double stranded messenger RNA with maintained translational activity through hybridization with poly A sequences for effective vaccination. Biomaterials. 2017.09; ( PubMed , DOI )

  13. Matsumoto Hirotaka, Kiryu Hisanori, Furusawa Chikara, Ko Minoru S. H., Ko Shigeru B. H., Gouda Norio, Hayashi Tetsutaro, Nikaido Itoshi: SCODE: an efficient regulatory network inference algorithm from single-cell RNA-Seq during differentiation BIOINFORMATICS. 2017.08; 33 (15): 2314-2321. ( PubMed , DOI )

  14. Dian-Jang Lee, Eva Kessel, Taavi Lehto, Xueying Liu, Naoto Yoshinaga, Kärt Padari, Ying-Chen Chen, Susanne Kempter, Satoshi Uchida, Joachim O. Rädler, Margus Pooga, Ming-Thau Sheu, Kazunori Kataoka, Ernst Wagner: Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia Bioconjugate Chemistry. 2017.08; 28 (9): 2393-2409. ( DOI )

  15. Ikura Teikichi, Ito Nobutoshi: タウタンパク質に対するPin1由来のプロテアーゼの活性の定量的評価(Quantitative evaluation of activity of a protease derived from Pin1 for tau protein) 生物物理. 2017.08; 57 (Suppl.1-2): S315. ( 医中誌 )

  16. Numoto Nobutaka, Akatsu Chizuru, Shinagawa Kenro, Tsubata Takeshi, Ito Nobutoshi: B細胞抑制性因子CD72の分子表面電荷分布によるリガンド結合制御機構(Charge distribution regulates the ligand-binding affinity of B cell inhibitory receptor CD72) 生物物理. 2017.08; 57 (Suppl.1-2): S276. ( 医中誌 )

  17. Horibata Y, Ando H, Satou M, Shimizu H, Mitsuhashi S, Shimizu Y, Itoh M, Sugimoto H: Identification of the N-terminal transmembrane domain of StarD7 and its importance for mitochondrial outer membrane localization and phosphatidylcholine transfer. Scientific reports. 2017.08; 7 (1): 8793. ( PubMed , DOI )

  18. Saha M, Mitsuhashi S, Jones MD, Manko K, Reddy HM, Bruels CC, Cho KA, Pacak CA, Draper I, Kang PB: Consequences of MEGF10 deficiency on myoblast function and Notch1 interactions. Human molecular genetics. 2017.08; 26 (15): 2984-3000. ( PubMed , DOI )

  19. Okubo M, Goto K, Komaki H, Nakamura H, Mori-Yoshimura M, Hayashi YK, Mitsuhashi S, Noguchi S, Kimura E, Nishino I: Comprehensive analysis for genetic diagnosis of Dystrophinopathies in Japan. Orphanet journal of rare diseases. 2017.08; 12 (1): 149. ( PubMed , DOI )

  20. Ishigaki Kazuyoshi, Kochi Yuta, Suzuki Akari, Tsuchida Yumi, Tsuchiya Haruka, Sumitomo Shuji, Yamaguchi Kensuke, Nagafuchi Yasuo, Nakachi Shinichiro, Kato Rika, Sakurai Keiichi, Shoda Hirofumi, Ikari Katsunori, Taniguchi Atsuo, Yamanaka Hisashi, Miya Fuyuki, Tsunoda Tatsuhiko, Okada Yukinori, Momozawa Yukihide, Kamatani Yoichiro, Yamada Ryo, Kubo Michiaki, Fujio Keishi, Yamamoto Kazuhiko: Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis NATURE GENETICS. 2017.07; 49 (7): 1120-+. ( PubMed , DOI )

  21. Mitsuhashi S, Kryukov K, Nakagawa S, Takeuchi JS, Shiraishi Y, Asano K, Imanishi T: A portable system for rapid bacterial composition analysis using a nanopore-based sequencer and laptop computer. Scientific reports. 2017.07; 7 (1): 5657. ( PubMed , DOI )

  22. Nitta T, Kochi Y, Muro R, Tomofuji Y, Okamura T, Murata S, Suzuki H, Sumida T, Yamamoto K, Takayanagi H: Human thymoproteasome variations influence CD8 T cell selection. Science immunology. 2017.06; 2 (12): ( PubMed , DOI )

  23. Yuichi Amano, Masaki Kikuchi, Shin Sato, Shigeyuki Yokoyama, Takashi Umehara, Naoki Umezawa, Tsunehiko Higuchi: Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1. Bioorganic & Medicinal Chemistry. 2017.05; 25 (9): 2617-2624. ( DOI )

  24. Nagano-Shoji M, Hamamoto Y, Mizuno Y, Yamada A, Kikuchi M, Shirouzu M, Umehara T, Yoshida M, Nishiyama M, Kosono S: Characterization of lysine acetylation of a phosphoenolpyruvate carboxylase involved in glutamate overproduction in Corynebacterium glutamicum. Molecular Microbiology. 2017.05;

  25. Hiraku Ohno, Kazuki Takeda, Satomi Niwa, Tomotaka Tsujinaka, Yuya Hanazono, Yu Hirano, Kunio Miki: Crystallographic characterization of the high-potential iron-sulfur protein in the oxidized state at 0.8 Å resolution. PLoS One. 2017.05; 12 (5): e0178183. ( PubMed , DOI )

  26. Yuki Mochida, Horacio Cabral, Kazunori Kataoka: Polymeric micelles for targeted tumor therapy of platinum anticancer drugs. Expert Opinion on Drug Delivery. 2017.03; 14 (12): 1423-1438. ( DOI )

  27. Molineros JE, Yang W, Zhou XJ, Sun C, Okada Y, Zhang H, Heng Chua K, Lau YL, Kochi Y, Suzuki A, Yamamoto K, Ma J, Bang SY, Lee HS, Kim K, Bae SC, Zhang H, Shen N, Looger LL, Nath SK: Confirmation of five novel susceptibility loci for systemic lupus erythematosus (SLE) and integrated network analysis of 82 SLE susceptibility loci. Human molecular genetics. 2017.03; 26 (6): 1205-1216. ( PubMed , DOI )

  28. Federico Perche, Satoshi Uchida, Hiroki Akiba, Chin-Yu Lin, Masaru Ikegami, Anjaneyulu Dirisala, Toshihiro Nakashima, Keiji Itaka, Kohei Tsumoto, Kazunori Kataoka: Improved Brain Expression of Anti-Amyloid β scFv by Complexation of mRNA Including a Secretion Sequence with PEG-based Block Catiomer. Curr Alzheimer Res. 2017.03; 14 (3): 295-302. ( PubMed , DOI )

  29. Ueda MT, Kurosaki Y, Izumi T, Nakano Y, Oloniniyi OK, Yasuda J, Koyanagi Y, Sato K, Nakagawa S: Functional mutations in spike glycoprotein of Zaire ebolavirus associated with an increase in infection efficiency. Genes to cells : devoted to molecular & cellular mechanisms. 2017.02; 22 (2): 148-159. ( PubMed , DOI )

  30. Reddy HM, Cho KA, Lek M, Estrella E, Valkanas E, Jones MD, Mitsuhashi S, Darras BT, Amato AA, Lidov HG, Brownstein CA, Margulies DM, Yu TW, Salih MA, Kunkel LM, MacArthur DG, Kang PB: The sensitivity of exome sequencing in identifying pathogenic mutations for LGMD in the United States. Journal of human genetics. 2017.02; 62 (2): 243-252. ( PubMed , DOI )

  31. Nishikawa A, Mitsuhashi S, Miyata N, Nishino I: Targeted massively parallel sequencing and histological assessment of skeletal muscles for the molecular diagnosis of inherited muscle disorders. Journal of medical genetics. 2017.02; 54 (2): 104-110. ( PubMed , DOI )

  32. Liang WC, Uruha A, Suzuki S, Murakami N, Takeshita E, Chen WZ, Jong YJ, Endo Y, Komaki H, Fujii T, Kawano Y, Mori-Yoshimura M, Oya Y, Xi J, Zhu W, Zhao C, Watanabe Y, Ikemoto K, Nishikawa A, Hamanaka K, Mitsuhashi S, Suzuki N, Nishino I: Pediatric necrotizing myopathy associated with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase antibodies. Rheumatology (Oxford, England). 2017.02; 56 (2): 287-293. ( PubMed , DOI )

  33. Zhu W, Mitsuhashi S, Yonekawa T, Noguchi S, Huei JC, Nalini A, Preethish-Kumar V, Yamamoto M, Murakata K, Mori-Yoshimura M, Kamada S, Yahikozawa H, Karasawa M, Kimura S, Yamashita F, Nishino I: Missing genetic variations in GNE myopathy: rearrangement hotspots encompassing 5'UTR and founder allele. Journal of human genetics. 2017.02; 62 (2): 159-166. ( PubMed , DOI )

  34. Sasagawa Yohei, Nikaido Itoshi, Hayashi Tetsutaro, Danno Hiroki, Uno Kenichiro D., Imai Takeshi, Ueda Hiroki R.: Quartz-Seq: a highly reproducible and sensitive single-cell RNA sequencing method, reveals non-genetic gene-expression heterogeneity (vol 14, R31, 2013) GENOME BIOLOGY. 2017.01; 18 (1): 9. ( PubMed , DOI )

  35. Satomi Inaba, Nobutaka Numoto, Shuhei Ogawa, Hisayuki Morii, Teikichi Ikura, Ryo Abe, Nobutoshi Ito, Masayuki Oda: Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins. J. Biol. Chem.. 2017.01; 292 (3): 1052-1060. ( PubMed , DOI )

  36. Miyatake S, Mitsuhashi S, Hayashi YK, Purevjav E, Nishikawa A, Koshimizu E, Suzuki M, Yatabe K, Tanaka Y, Ogata K, Kuru S, Shiina M, Tsurusaki Y, Nakashima M, Mizuguchi T, Miyake N, Saitsu H, Ogata K, Kawai M, Towbin J, Nonaka I, Nishino I, Matsumoto N: Biallelic Mutations in MYPN, Encoding Myopalladin, Are Associated with Childhood-Onset, Slowly Progressive Nemaline Myopathy. American journal of human genetics. 2017.01; 100 (1): 169-178. ( PubMed , DOI )

  37. Kulkarni Manjiri R., Islam Monirul, Numoto Nobutaka, Elahi Montasir, Ito Nobutoshi, Kuroda Yutaka: Crystallographic studies of sero-specific Dengue ED3 immune response ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES. 2017; 73 A404. ( DOI )

  38. Kulkarni Manjiri Ravindra, Islam Monirul, Numoto Nobutaka, Ito Nobutoshi, Kuroda Yutaka: Crystal structures of dengue virus protein revealed ED3 sero-specificity ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES. 2017; 73 C394. ( DOI )

  39. Tsuchida Y, Sumitomo S, Ishigaki K, Suzuki A, Kochi Y, Tsuchiya H, Ota M, Komai T, Inoue M, Morita K, Okamura T, Yamamoto K, Fujio K: TGF-β3 Inhibits Antibody Production by Human B Cells. PloS one. 2017; 12 (1): e0169646. ( PubMed , DOI )

  1. Chizuru Akatsu, Kenro Shinagawa, Nobutaka Numoto, Zhihong Liu, Ayse Konuskan Ucar, Mohammad Aslam, Shirly Phoon, Takahiro Adachi, Koji Furukawa, Nobutoshi Ito, Takeshi Tsubata: CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP. J. Exp. Med.. 2016.11; 213 (12): 2691-2706. ( PubMed , DOI )

  2. Qixian Chen, Kensuke Osada, Zhishen Ge, Satoshi Uchida, Theofilus A. Tockary, Anjaneyulu Dirisala, Akitsugu Matsui, Kazuko Toh, Kaori M. Takeda, Xueying Liu, Takahiro Nomoto, Tekihiko Ishii, Makoto Oba, Yu Matsumoto, Kazunori Kataoka: Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting Biomaterials. 2016.10; 113 253-265. ( DOI )

  3. Termglinchan T, Hisamatsu S, Ohmori J, Suzumura H, Sumitomo N, Imataka G, Arisaka O, Murakami N, Minami N, Akihiko I, Sasaki M, Goto Y, Noguchi S, Nonaka I, Mitsuhashi S, Nishino I: Novel TK2 mutations as a cause of delayed muscle maturation in mtDNA depletion syndrome. Neurology. Genetics. 2016.10; 2 (5): e95. ( PubMed , DOI )

  4. Reddy HM, Hamed SA, Lek M, Mitsuhashi S, Estrella E, Jones MD, Mahoney LJ, Duncan AR, Cho KA, Macarthur DG, Kunkel LM, Kang PB: Homozygous nonsense mutation in SGCA is a common cause of limb-girdle muscular dystrophy in Assiut, Egypt. Muscle & nerve. 2016.10; 54 (4): 690-5. ( PubMed , DOI )

  5. Yuya Hanazono, Kazuki Takeda, Kunio Miki: Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein. Sci Rep. 2016.10; 6 34654. ( PubMed , DOI )

  6. Miyake N, Fukai R, Ohba C, Chihara T, Miura M, Shimizu H, Kakita A, Imagawa E, Shiina M, Ogata K, Okuno-Yuguchi J, Fueki N, Ogiso Y, Suzumura H, Watabe Y, Imataka G, Leong HY, Fattal-Valevski A, Kramer U, Miyatake S, Kato M, Okamoto N, Sato Y, Mitsuhashi S, Nishino I, Kaneko N, Nishiyama A, Tamura T, Mizuguchi T, Nakashima M, Tanaka F, Saitsu H, Matsumoto N: Biallelic TBCD Mutations Cause Early-Onset Neurodegenerative Encephalopathy. American journal of human genetics. 2016.10; 99 (4): 950-961. ( PubMed , DOI )

  7. Satoshi Uchida, Kentaro Hayakawa, Toru Ogata, Sakae Tanaka, Kazunori Kataoka, Keiji Itaka: Treatment of spinal cord injury by an advanced cell transplantation technology using brain-derived neurotrophic factor-transfected mesenchymal stem cell spheroids Biomaterials. 2016.09; 109 1-11. ( DOI )

  8. Tomomi Imamura, Kyota Fujita, Kazuhiko Tagawa, Teikichi Ikura, Xigui Chen, Hidenori Homma, Takuya Tamura, Ying Mao, Juliana Bosso Taniguchi, Kazumi Motoki, Makoto Nakabayashi, Nobutoshi Ito, Kazunori Yamada, Kentaro Tomii, Hideyuki Okano, Julia Kaye, Steven Finkbeiner, Hitoshi Okazawa: Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries. Sci Rep. 2016.09; 6 33861. ( PubMed , DOI )

  9. Takayama K, Mitsuhashi S, Shin JY, Tanaka R, Fujii T, Tsuburaya R, Mukaida S, Noguchi S, Nonaka I, Nishino I: Japanese multiple epidermal growth factor 10 (MEGF10) myopathy with novel mutations: A phenotype-genotype correlation. Neuromuscular disorders : NMD. 2016.09; 26 (9): 604-9. ( PubMed , DOI )

  10. Hamanaka K, Goto K, Arai M, Nagao K, Obuse C, Noguchi S, Hayashi YK, Mitsuhashi S, Nishino I: Corrigendum to "Clinical, muscle pathological, and genetic features of Japanese facioscapulohumeral muscular dystrophy 2 (FSHD2) patients with SMCHD1 mutations": [Neuromuscular Disorders 26/4-5 (2016) 300-308]. Neuromuscular disorders : NMD. 2016.07; 26 (7): 472. ( PubMed , DOI )

  11. Chin-Yu Lin, Federico Perche, Masaru Ikegami, Satoshi Uchida, Kazunori Kataoka, Keiji Itaka: Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles Journal of Controlled Release. 2016.06; 235 268-275. ( DOI )

  12. Okubo M, Minami N, Goto K, Goto Y, Noguchi S, Mitsuhashi S, Nishino I: Genetic diagnosis of Duchenne/Becker muscular dystrophy using next-generation sequencing: validation analysis of DMD mutations. Journal of human genetics. 2016.06; 61 (6): 483-9. ( PubMed , DOI )

  13. Yuya Hanazono, Kazuki Takeda, Kunio Miki: Characterization of the Nqo5 subunit of bacterial complex I in the isolated state. FEBS Open Bio. 2016.06; 6 (7): 687-695. ( PubMed , DOI )

  14. Ming Wang, Yutaka Miura, Kenji Tsuchihashi, Kazuki Miyano, Osamu Nagano, Momoko Yoshikawa, Ami Tanabe, Jun Makino, Yuki Mochida, Nobuhiro Nishiyama, Hideyuki Saya, Horacio Cabral, Kazunori Kataoka: Eradication of CD44-variant positive population in head and neck tumors through controlled intracellular navigation of cisplatin-loaded nanomedicines. Journal of Controlled Release. 2016.05; 230 26-33. ( DOI )

  15. van den Boogaard ML, Lemmers RJLF, Balog J, Wohlgemuth M, Auranen M, Mitsuhashi S, van der Vliet PJ, Straasheijm KR, van den Akker RFP, Kriek M, Laurense-Bik MEY, Raz V, van Ostaijen-Ten Dam MM, Hansson KBM, van der Kooi EL, Kiuru-Enari S, Udd B, van Tol MJD, Nishino I, Tawil R, Tapscott SJ, van Engelen BGM, van der Maarel SM: Mutations in DNMT3B Modify Epigenetic Repression of the D4Z4 Repeat and the Penetrance of Facioscapulohumeral Dystrophy. American journal of human genetics. 2016.05; 98 (5): 1020-1029. ( PubMed , DOI )

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  1. Yusuke Watarai, Michiyasu Ishizawa, Teikichi Ikura, Flavia C M Zacconi, Shigeyuki Uno, Nobutoshi Ito, Antonio Mouriño, Hiroaki Tokiwa, Makoto Makishima, Sachiko Yamada: Synthesis, Biological Activities, and X-ray Crystal Structural Analysis of 25-Hydroxy-25(or 26)-adamantyl-17-[20(22),23-diynyl]-21-norvitamin D Compounds. J. Med. Chem.. 2015.12; 58 (24): 9510-9521. ( PubMed , DOI )

  2. Satoshi Uchida, Hiroaki Kinoh, Takehiko Ishii, Akitsugu Matsui, Theofilus Agrios Tockary, Kaori Machitani Takeda, Hirokuni Uchida, Kensuke Osada, Keiji Itaka, Kazunori Kataoka: Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety Biomaterials. 2015.12; 82 221-228. ( DOI )

  3. Jun Makino, Horacio Cabral, Yutaka Miura, Yu Matsumoto, Ming Wang, Hiroaki Kinoh, Yuki Mochida, Nobuhiro Nishiyama, Kazunori Kataoka: cRGD-installed polymeric micelles loading platinum anticancer drugs enable cooperative treatment against lymph node metastasis. Journal of Controlled Release. 2015.12; 220 783-791. ( DOI )

  4. Mariko Yamane, Setsuko Fujii, Satoshi Ohtsuka, Hitoshi Niwa: Zscan10 is dispensable for maintenance of pluripotency in mouse embryonic stem cells BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015.12; 468 (4): 826-831. ( PubMed , DOI )

  5. 小杉 孝嗣, 笹川 洋平, 渡辺 直子, 二階堂 愛: 転写ネットワーク変化を網羅的に同定するシークエンス技術の開発 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015.12; 88回・38回 [3P0819].

  6. Yasuaki Anami, Yuta Sakamaki, Toshimasa Itoh, Yuka Inaba, Makoto Nakabayashi, Teikichi Ikura, Nobutoshi Ito, Keiko Yamamoto: Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activity. Bioorg. Med. Chem.. 2015.11; 23 (22): 7274-7281. ( PubMed , DOI )

  7. Omer Faruk Mutaf, Akihiro Kishimura, Yuki Mochida, Ahram Kim, Kazunori Kataoka: Induction of Secondary Structure through Micellization of an Oppositely Charged Pair of Homochiral Block‐and Homopolypeptides in an Aqueous Medium. Macromolar Rapid Communications. 2015.11; 36 (22): 1958-1964. ( DOI )

  8. Ando H, Aoyama C, Horibata Y, Satou M, Mitsuhashi S, Itoh M, Hosaka K, Sugimoto H: Transcriptional suppression of CTP:phosphoethanolamine cytidylyltransferase by 25-hydroxycholesterol is mediated by nuclear factor-Y and Yin Yang 1. The Biochemical journal. 2015.11; 471 (3): 369-79. ( PubMed , DOI )

  9. Akitsugu Matsui, Satoshi Uchida, Takehiko Ishii, Keiji Itaka, Kazunori Kataoka: Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases Scientific Reports . 2015.10; 5 1-10. ( DOI )

  10. Manjiri R Kulkarni, Monirul M Islam, Nobutaka Numoto, Montasir Elahi, Mamunur R Mahib, Nobutoshi Ito, Yutaka Kuroda: Structural and biophysical analysis of sero-specific immune responses using epitope grafted Dengue ED3 mutants. Biochim. Biophys. Acta. 2015.10; 1854 (10 Pt A): 1438-1443. ( PubMed , DOI )

  11. Izumi R, Warita H, Niihori T, Takahashi T, Tateyama M, Suzuki N, Nishiyama A, Shirota M, Funayama R, Nakayama K, Mitsuhashi S, Nishino I, Aoki Y, Aoki M: Isolated inclusion body myopathy caused by a multisystem proteinopathy-linked hnRNPA1 mutation. Neurology. Genetics. 2015.10; 1 (3): e23. ( PubMed , DOI )

  12. Zhao Y, Ogawa H, Yonekura S, Mitsuhashi H, Mitsuhashi S, Nishino I, Toyoshima C, Ishiura S: Functional analysis of SERCA1b, a highly expressed SERCA1 variant in myotonic dystrophy type 1 muscle. Biochimica et biophysica acta. 2015.10; 1852 (10 Pt A): 2042-7. ( PubMed , DOI )

  13. Masaki Kinoshita, Daisuke Shimosato, Mariko Yamane, Hitoshi Niwa: Sox7 is dispensable for primitive endoderm differentiation from mouse ES cells BMC DEVELOPMENTAL BIOLOGY. 2015.10; 15 37. ( PubMed , DOI )

  14. Tomoyuki Okuda, Yumiko Suzuki, Yuko Kobayashi, Takehiko Ishii, Satoshi Uchida, Keiji Itaka, Kazunori Kataoka, Hirokazu Okamoto: Development of biodegradable polycation-based inhalable dry gene powders by spray freeze drying Pharmaceutics. 2015.08; 7 (3): 233-254. ( DOI )

  15. Masaki S, Kii I, Sumida Y, Kato-Sumida T, Ogawa Y, Ito N, Nakamura M, Sonamoto R, Kataoka N, Hosoya T, Hagiwara M: Design and synthesis of a potent inhibitor of class 1 DYRK kinases as a suppressor of adipogenesis. Bioorg Med Chem. 2015.08; 23 (15): 4434-4441. ( PubMed , DOI )

  16. Morooka S, Hoshina M, Kii I, Okabe T, Kojima H, Inoue N, Okuno Y, Denawa M, Yoshida S, Fukuhara J, Ninomiya K, Ikura T, Furuya T, Nagano T, Noda K, Ishida S, Hosoya T, Ito N, Yoshimura N, Hagiwara M: Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice. Mol Pharmacol. 2015.08; 88 (2): 316-325. ( PubMed , DOI )

  17. G. Morota, F. Penagaricano, J. L. Petersen, D. C. Ciobanu, K. Tsuyuzaki, I. Nikaido: An application of MeSH enrichment analysis in livestock ANIMAL GENETICS. 2015.08; 46 (4): 381-387. ( PubMed , DOI )

  18. Yanmin Li, Kensuke Osada, Qixian Chen, Theofilus A Tockary, Anjaneyulu Dirisala, Kaori M Takeda, Satoshi Uchida, Kazuya Nagata, Keiji Itaka, Kazunori Kataoka: Toroidal packaging of pDNA into block ionomer micelles exerting promoted in vivo gene expression Biomacromolecules. 2015.07; 16 (9): 2664-2671. ( DOI )

  19. Uruha A, Noguchi S, Sato W, Nishimura H, Mitsuhashi S, Yamamura T, Nishino I: Plasma IP-10 level distinguishes inflammatory myopathy. Neurology. 2015.07; 85 (3): 293-4. ( PubMed , DOI )

  20. Satoshi Uchida, Kazunori Kataoka, Keiji Itaka: Screening of mRNA chemical modification to maximize protein expression with reduced immunogenicity Pharmaceutics. 2015.07; 7 (3): 137-151. ( DOI )

  21. Uruha A, Hayashi YK, Oya Y, Mori-Yoshimura M, Kanai M, Murata M, Kawamura M, Ogata K, Matsumura T, Suzuki S, Takahashi Y, Kondo T, Kawarabayashi T, Ishii Y, Kokubun N, Yokoi S, Yasuda R, Kira J, Mitsuhashi S, Noguchi S, Nonaka I, Nishino I: Necklace cytoplasmic bodies in hereditary myopathy with early respiratory failure. Journal of neurology, neurosurgery, and psychiatry. 2015.05; 86 (5): 483-9. ( PubMed , DOI )

  22. Setsuko Fujii, Satomi Nishikawa-Torikai, Yoko Futatsugi, Yayoi Toyooka, Mariko Yamane, Satoshi Ohtsuka, Hitoshi Niwa: Nr0b1 is a negative regulator of Zscan4c in mouse embryonic stem cells SCIENTIFIC REPORTS. 2015.03; 5 9146. ( PubMed , DOI )

  23. Koki Tsuyuzaki, Gota Morota, Manabu Ishii, Takeru Nakazato, Satoru Miyazaki, Itoshi Nikaido: MeSH ORA framework: R/Bioconductor packages to support MeSH over-representation analysis BMC BIOINFORMATICS. 2015.02; 16 45. ( PubMed , DOI )

  24. Qixian Chen, Kensuke Osada, Matthew Pennisi, Satoshi Uchida, Theofilus A. Tockary, Anjaneyulu Dirisala, Yanmin Li, Kaori M. Takeda, Satoshi Oniyanagi, Keiji Itaka, Kazunori Kataoka: A tadpole-shaped gene carrier with distinct phase segregation in a ternary polymeric micelle Soft matter. 2015.02; 11 (14): 2718-2722. ( DOI )

  25. Liang WC, Zhu W, Mitsuhashi S, Noguchi S, Sacher M, Ogawa M, Shih HH, Jong YJ, Nishino I: Congenital muscular dystrophy with fatty liver and infantile-onset cataract caused by TRAPPC11 mutations: broadening of the phenotype. Skeletal muscle. 2015; 5 29. ( PubMed , DOI )

  1. Kentaro Hayakawa, Satoshi Uchida, Toru Ogata, Sakae Tanaka, Kazunori Kataoka, Keiji Itaka: Intrathecal injection of a therapeutic gene-containing polyplex to treat spinal cord injury Journal of Controlled Release. 2014.11; 197 1-9. ( DOI )

  2. Draper I, Mahoney LJ, Mitsuhashi S, Pacak CA, Salomon RN, Kang PB: Silencing of drpr leads to muscle and brain degeneration in adult Drosophila. The American journal of pathology. 2014.10; 184 (10): 2653-61. ( PubMed , DOI )

  3. S. Quader, H. Cabral, Y. Mochida, T. Ishii, X. Liu, K. Toh, H. Kinoh, Y. Miura, N. Nishiyama, K. Kataoka: Selective intracellular delivery of proteasome inhibitors through pH-sensitive polymeric micelles directed to efficient antitumor therapy. Journal of Controlled Release. 2014.08; 188 67-77. ( DOI )

  4. Yamamoto M, Onogi H, Kii I, Yoshida S, Iida K, Sakai H, Abe M, Tsubota T, Ito N, Hosoya T, Hagiwara M: CDK9 inhibitor FIT-039 prevents replication of multiple DNA viruses. J Clin Invest. 2014.08; 124 (8): 3479-3488. ( PubMed , DOI )

  5. Yuki Mochida, Horacio Cabral, Yutaka Miura, Francesco Albertini, Shigeto Fukushima, Kensuke Osada, Nobuhiro Nishiyama, Kazunori Kataoka: Bundled Assembly of Helical Nanostructures in Polymeric Micelles Loaded with Platinum Drugs Enhancing Therapeutic Efficiency against Pancreatic Tumor. ACS Nano. 2014.06; 8 (7): 6724-6738. ( DOI )

  6. Kudo Takeru, Ishizawa Michiyasu, Maekawa Kazuki, Nakabayashi Makoto, Watarai Yusuke, Uchida Hikaru, Tokiwa Hiroaki, Ikura Teikichi, Ito Nobutoshi, Makishima Makoto, Yamada Sachiko: Combination of triple bond and adamantane ring on the vitamin D side chain produced partial agonists for vitamin D receptor. J Med Chem. 2014.05; 57 (10): 4073-4087. ( PubMed , DOI )

  7. Shunsuke Ito, Mariko Yamane, Satoshi Ohtsuka, Hitoshi Niwa: The C-terminal region of Xpc is dispensable for the transcriptional activity of Oct3/4 in mouse embryonic stem cells FEBS LETTERS. 2014.04; 588 (7): 1128-1135. ( PubMed , DOI )

  8. Anjaneyulu Dirisala, Kensuke Osada, Qixian Chen, Theofilus A. Tockary, Kaori Machitani, Shigehito Osawa, Xueying Liu, Takehiko Ishii, Kanjiro Miyata, Makoto Oba, Satoshi Uchida, Keiji Itaka, Kazunori Kataoka: Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors Biomaterials. 2014.04; 35 (20): 5359-5368. ( DOI )

  9. Kazuya Nagata, Keiji Itaka, Miyuki Baba, Satoshi Uchida, Takehiko Ishii, Kazunori Kataoka: Muscle-targeted hydrodynamic gene introduction of insulin-like growth factor-1 using polyplex nanomicelle to treat peripheral nerve injury Journal of Controlled Release. 2014.03; 183 27-34. ( DOI )

  10. Furusawa Yoshihiko, Mitsuhashi Satomi, Mori-Yoshimura Madoka, Shimada Yohta, Yamamoto Toshiyuki, Shibuya Makoto, Shimizu Jun, Ohashi Toya, Saito Yuko, Nishino Ichizo, Oya Yasushi, Murata Miho: 酵素補充療法から4年後に発症した遅発型ポンぺ病　剖検例(Late-onset Pompe disease after 4 years of enzyme replacement therapy: An autopsy case) Neurology and Clinical Neuroscience. 2014.01; 2 (1): 7-9. ( 医中誌 )

  11. Zhishen Ge, Qixian Chen, Kensuke Osada, Xueying Liu, Theofilus A. Tockary, Satoshi Uchida, Anjaneyulu Dirisala, Takehiko Ishii, Takahiro Nomoto, Kazuko Toh, Yu Matsumoto, Makoto Oba, Mitsunobu R. Kano, Keiji Itaka, Kazunori Kataoka: Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors Biomaterials. 2014.01; 35 (10): 3416-3426. ( DOI )

  1. Satoshi Uchida, Keiji Itaka, Takahiro Nomoto, Taisuke Endo, Yu Matsumoto, Takehiko Ishii, Kazunori Kataoka: An injectable spheroid system with genetic modification for cell transplantation therapy Biomaterials. 2013.12; 35 (8): 2499-2506. ( DOI )

  2. Mitsuhashi S, Boyden SE, Estrella EA, Jones TI, Rahimov F, Yu TW, Darras BT, Amato AA, Folkerth RD, Jones PL, Kunkel LM, Kang PB: Exome sequencing identifies a novel SMCHD1 mutation in facioscapulohumeral muscular dystrophy 2. Neuromuscular disorders : NMD. 2013.12; 23 (12): 975-80. ( PubMed , DOI )

  3. Kenjiro Adachi, Itoshi Nikaido, Hiroshi Ohta, Satoshi Ohtsuka, Hiroki Ura, Mitsutaka Kadota, Teruhiko Wakayama, Hiroki R. Ueda, Hitoshi Niwa: Context-Dependent Wiring of Sox2 Regulatory Networks for Self-Renewal of Embryonic and Trophoblast Stem Cells MOLECULAR CELL. 2013.11; 52 (3): 380-392. ( PubMed , DOI )

  4. Mitsuhashi S, Nishino I: Megaconial congenital muscular dystrophy due to loss-of-function mutations in choline kinase β. Current opinion in neurology. 2013.10; 26 (5): 536-43. ( PubMed , DOI )

  5. Masaki Shigeta, Satoshi Ohtsuka, Satomi Nishikawa-Torikai, Mariko Yamane, Setsuko Fujii, Kazuhiro Murakami, Hitoshi Niwa: Maintenance of pluripotency in mouse ES cells without Trp53 Scientific Reports. 2013.10; 3 2944. ( PubMed , DOI )

  6. Ikura Teikichi, Ito Nobutoshi: Peptidyl-prolyl isomerase activity of FK506 binding protein 12 prevents tau peptide from aggregating. Protein Eng Des Sel. 2013.09; 26 (9): 539-546. ( PubMed , DOI )

  7. Nakabayashi Makoto, Tsukahara Yoshito, Iwasaki-Miyamoto Yukiko, Mihori-Shimazaki Mika, Yamada Sachiko, Inaba Satomi, Oda Masayuki, Shimizu Masato, Makishima Makoto, Tokiwa Hiroaki, Ikura Teikichi, Ito Nobutoshi: Crystal structures of hereditary vitamin D-resistant rickets-associated vitamin D receptor mutants R270L and W282R bound to 1,25-dihydroxyvitamin D3 and synthetic ligands. J Med Chem. 2013.09; 56 (17): 6745-6760. ( PubMed , DOI )

  8. Mitsuhashi S, Mitsuhashi H, Alexander MS, Sugimoto H, Kang PB: Cysteine mutations cause defective tyrosine phosphorylation in MEGF10 myopathy. FEBS letters. 2013.09; 587 (18): 2952-7. ( PubMed , DOI )

  9. Higo K, Ikura T, Oda M, Morii H, Takahashi J, Abe R, Ito N: High resolution crystal structure of the Grb2 SH2 domain with a phosphopeptide derived from CD28 PLoS One. 2013.08; 8 (9): e74482. ( DOI )

  10. Masuno Hiroyuki, Ikura Teikichi, Morizono Daisuke, Orita Isamu, Yamada Sachiko, Shimizu Masato, Ito Nobutoshi: Crystal structures of complexes of vitamin D receptor ligand-binding domain with lithocholic acid derivatives. J Lipid Res. 2013.08; 54 (8): 2206-2213. ( PubMed , DOI )

  11. Chou PC, Liang WC, Nonaka I, Mitsuhashi S, Nishino I, Jong YJ: Intranuclear rods myopathy with autonomic dysfunction. Brain & development. 2013.08; 35 (7): 686-9. ( PubMed , DOI )

  12. Masaki Kikuchi, Shinichiro Iwabuchi, Tatsuhiko Kikkou, Keiichi Noguchi, Masafumi Odaka, Masafumi Yohda, Masaaki Kawata, Chikara Sato, Osamu Matsumoto: Expression, purification, crystallization and preliminary crystallographic analysis of hepatitis B virus core protein dimerized via a peptide linker containing an EGFP insertion. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013.08; 69 (Pt 8): 942-945. ( PubMed , DOI )

  13. Theofilus A. Tockary, Kensuke Osada, Qixian Chen, Kaori Machitani, Anjaneyulu Dirisala, Satoshi Uchida, Takahiro Nomoto, Kazuko Toh, Yu Matsumoto, Keiji Itaka, Koji Nitta, Kuniaki Nagayama, Kazunori Kataoka: Tethered PEG Crowdedness Determining Shape and Blood Circulation Profile of Polyplex Micelle Gene Carriers Macromolecules. 2013.08; 46 (16): 6585-6592. ( DOI )

  14. Hiroyasu Takemoto, Kanjiro Miyata, Shota Hattori, Takehiko Ishii, Tomoya Suma, Satoshi Uchida, Nobuhiro Nishiyama, Kazunori Kataoka: Acidic pH‐Responsive siRNA Conjugate for Reversible Carrier Stability and Accelerated Endosomal Escape with Reduced IFNα‐Associated Immune Response Angewandte Chemie International Edition. 2013.04; 125 (24): 6338-6341. ( DOI )

  15. Nobuo Yoshimoto, Akiko Kida, Xu Jie, Masaya Kurokawa, Masumi Iijima, Tomoaki Niimi, Andres D. Maturana, Itoshi Nikaido, Hiroki R. Ueda, Kenji Tatematsu, Katsuyuki Tanizawa, Akihiko Kondo, Ikuo Fujii, Shun'ichi Kuroda: An automated system for high-throughput single cell-based breeding SCIENTIFIC REPORTS. 2013.02; 3 1191. ( PubMed , DOI )

  16. Masaki Kikuchi, Shinichiro Iwabuchi, Tatsuhiko Kikkou, Keiichi Noguchi, Masafumi Odaka, Masafumi Yohda, Masaaki Kawata, Chikara Sato, Osamu Matsumoto: Expression, purification, crystallization and preliminary X-ray crystallographic studies of hepatitis B virus core fusion protein corresponding to octahedral particles. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013.02; 69 (Pt 2): 165-169. ( PubMed , DOI )

  17. Satoshi Uchida, Keiji Itaka, Hirokuni Uchida, Kentaro Hayakawa, Toru Ogata, Takehiko Ishii, Shigeto Fukushima, Kensuke Osada, Kazunori Kataoka: In vivo messenger RNA introduction into the central nervous system using polyplex nanomicelle PLOS ONE. 2013.02; 8 (2): e56220. ( DOI )

  18. Mitsuhashi H, Mitsuhashi S, Lynn-Jones T, Kawahara G, Kunkel LM: Expression of DUX4 in zebrafish development recapitulates facioscapulohumeral muscular dystrophy. Human molecular genetics. 2013.02; 22 (3): 568-77. ( PubMed , DOI )

  19. Yuya Hanazono, Kazuki Takeda, Toshihiko Oka, Tetsuya Abe, Taichi Tomonari, Nobuhiko Akiyama, Yoshiki Aikawa, Masafumi Yohda, Kunio Miki: Nonequivalence observed for the 16-meric structure of a small heat shock protein, SpHsp16.0, from Schizosaccharomyces pombe. Structure. 2013.02; 21 (2): 220-228. ( PubMed , DOI )

  20. Higo Kunitake, Ikura Teikichi, Oda Masayuki, Morii Hisayuki, Takahashi Jun, Abe Ryo, Ito Nobutoshi: High resolution crystal structure of the Grb2 SH2 domain with a phosphopeptide derived from CD28. PLoS One. 2013; 8 (9): e74482. ( PubMed , DOI )

  21. Tomoko Nakanishi, Rumiko Saito, Makoto Taniguchi, Haruka Oda, Atsumi Soma, Mayu Yasunaga, Mariko Yamane, Kenzo Sato: In Vivo Determination of Vitamin D Function Using Transgenic Mice Carrying a Human Osteocalcin Luciferase Reporter Gene BIOMED RESEARCH INTERNATIONAL. 2013; 2013 895706. ( PubMed , DOI )

  1. Mitsuhashi S, Kang PB: Update on the genetics of limb girdle muscular dystrophy. Seminars in pediatric neurology. 2012.12; 19 (4): 211-8. ( PubMed , DOI )

  2. Naohiro Hori, Mariko Yamane, Kaori Kouno, Kenzo Sato: Induction of DNA Demethylation Depending on Two Sets of Sox2 and Adjacent Oct3/4 Binding Sites (Sox-Oct Motifs) within the Mouse H19/Insulin-like Growth Factor 2 (Igf2) Imprinted Control Region JOURNAL OF BIOLOGICAL CHEMISTRY. 2012.12; 287 (52): 44006-44016. ( PubMed , DOI )

  3. Yuko Okamura-Oho, Kazuro Shimokawa, Satoko Takemoto, Asami Hirakiyama, Sakiko Nakamura, Yuki Tsujimura, Masaomi Nishimura, Takeya Kasukawa, Koh-hei Masumoto, Itoshi Nikaido, Yasufumi Shigeyoshi, Hiroki R. Ueda, Gang Song, James Gee, Ryutaro Himeno, Hideo Yokota: Transcriptome Tomography for Brain Analysis in the Web-Accessible Anatomical Space PLOS ONE. 2012.09; 7 (9): e45373. ( PubMed , DOI )

  4. Taisuke Endo, Keiji Itaka, Momoko Shioyama, Satoshi Uchida, Kazunori Kataoka: Gene transfection to spheroid culture system on micropatterned culture plate by polyplex nanomicelle: a novel platform of genetically-modified cell transplantation Drug delivery and translational research . 2012.09; 2 (5): 398-405. ( DOI )

  5. Yuya Hanazono, Kazuki Takeda, Masafumi Yohda, Kunio Miki: Structural studies on the oligomeric transition of a small heat shock protein, StHsp14.0. J Mol Biol. 2012.09; 422 (1): 100-108. ( PubMed , DOI )

  6. Kensuke Osada, Horacio Cabral, Yuki Mochida, Sangeun Lee, Kazuya Nagata, Tetsuya Matsuura, Megumi Yamamoto, Yasutaka Anraku, Akihiro Kishimura, Nobuhiro Nishiyama, Kazunori Kataoka: Bioactive Polymeric Metallosomes Self-Assembled through Block Copolymer–Metal Complexation. Journal of the American Chemical Society. 2012.08; 134 (32): 13172-13175. ( DOI )

  7. Boyden SE, Mahoney LJ, Kawahara G, Myers JA, Mitsuhashi S, Estrella EA, Duncan AR, Dey F, DeChene ET, Blasko-Goehringer JM, Bönnemann CG, Darras BT, Mendell JR, Lidov HG, Nishino I, Beggs AH, Kunkel LM, Kang PB: Mutations in the satellite cell gene MEGF10 cause a recessive congenital myopathy with minicores. Neurogenetics. 2012.05; 13 (2): 115-24. ( PubMed , DOI )

  8. Yoshimoto Nobuko, Sakamaki Yuta, Haeta Minoru, Kato Akira, Inaba Yuka, Itoh Toshimasa, Nakabayashi Makoto, Ito Nobutoshi, Yamamoto Keiko: Butyl pocket formation in the vitamin D receptor strongly affects the agonistic or antagonistic behavior of ligands. J Med Chem. 2012.05; 55 (9): 4373-4381. ( PubMed , DOI )

  9. Kondo E, Nishimura T, Kosho T, Inaba Y, Mitsuhashi S, Ishida T, Baba A, Koike K, Nishino I, Nonaka I, Furukawa T, Saito K: Recessive RYR1 mutations in a patient with severe congenital nemaline myopathy with ophthalomoplegia identified through massively parallel sequencing. American journal of medical genetics. Part A. 2012.04; 158A (4): 772-8. ( PubMed , DOI )

  10. Qixian Chen, Kensuke Osada, Takehiko Ishii, Makoto Oba, Satoshi Uchida, Theofilus A. Tockary, Taisuke Endo, Zhishen Ge, Hiroaki Kinoh, Mitsunobu R. Kano, Keiji Itaka, Kazunori Kataoka: Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic anti-angiogenic gene therapy for fibrotic pancreatic tumors Biomaterials. 2012.03; 33 (18): 4722-4730. ( DOI )

  11. Nomura W, Masuda A, Ohba K, Urabe A, Ito N, Ryo A, Yamamoto N, Tamamura H: Effects of DNA binding of the zinc finger and linkers for domain fusion on the catalytic activity of sequence-specific chimeric recombinases determined by a facile fluorescent system. Biochemistry. 2012.02; 51 (7): 1510-1517. ( PubMed , DOI )

  12. Satoshi Uchida, Keiji Itaka, Qixian Chen, Kensuke Osada, Takehiko Ishii, Masa-Aki Shibata, Mariko Harada-Shiba, Kazunori Kataoka: PEGylated polyplex with optimized PEG shielding enhances gene introduction in lungs by minimizing inflammatory responses Molecular Therapy . 2012.02; 20 (6): 1196-1203. ( DOI )

  13. Tamashiro Tomonari, Tanabe Yoichi, Ikura Teikichi, Ito Nobutoshi, Oda Masayuki: Critical roles of Asp270 and Trp273 in the alpha-repeat of the carbohydrate-binding module of endo-1,3-beta-glucanase for laminarin-binding avidity. Glycoconj J. 2012.01; 29 (1): 77-85. ( PubMed , DOI )

  14. Takahashi M, Saitou N: Identification and characterization of lineage-specific highly conserved noncoding sequences in mammalian genomes. Genome Biology and Evolution. 2012; 4 641-657.

  1. Mitsuhashi S, Nishino I: Phospholipid synthetic defect and mitophagy in muscle disease. Autophagy. 2011.12; 7 (12): 1559-61. ( PubMed , DOI )

  2. Fujii Shinya, Masuno Hiroyuki, Taoda Yoshiyuki, Kano Atsushi, Wongmayura Angsuma, Nakabayashi Makoto, Ito Nobutoshi, Shimizu Masato, Kawachi Emiko, Hirano Tomoya, Endo Yasuyuki, Tanatani Aya, Kagechika Hiroyuki: Boron cluster-based development of potent nonsecosteroidal vitamin D receptor ligands: direct observation of hydrophobic interaction between protein surface and carborane. J Am Chem Soc. 2011.12; 133 (51): 20933-20941. ( PubMed , DOI )

  3. Tomoya Suma, Kanjiro Miyata, Takehiko Ishii, Satoshi Uchida, Hirokuni Uchida, Keiji Itaka, Nobuhiro Nishiyama, Kazunori Kataoka: Enhanced stability and gene silencing ability of siRNA-loaded polyion complexes formulated from polyaspartamide derivatives with a repetitive array of amino groups in the side chain Biomaterials. 2011.12; 33 (9): 2770-2779. ( DOI )

  4. Mitsuhashi S, Hatakeyama H, Karahashi M, Koumura T, Nonaka I, Hayashi YK, Noguchi S, Sher RB, Nakagawa Y, Manfredi G, Goto Y, Cox GA, Nishino I: Muscle choline kinase beta defect causes mitochondrial dysfunction and increased mitophagy. Human molecular genetics. 2011.10; 20 (19): 3841-51. ( PubMed , DOI )

  5. Takeya Kasukawa, Koh-hei Masumoto, Itoshi Nikaido, Mamoru Nagano, Kenichiro D. Uno, Kaori Tsujino, Carina Hanashima, Yasufumi Shigeyoshi, Hiroki R. Ueda: Quantitative Expression Profile of Distinct Functional Regions in the Adult Mouse Brain PLOS ONE. 2011.08; 6 (8): e23228. ( PubMed , DOI )

  6. Saito Y, Komaki H, Hattori A, Takeuchi F, Sasaki M, Kawabata K, Mitsuhashi S, Tominaga K, Hayashi YK, Nowak KJ, Laing NG, Nonaka I, Nishino I: Extramuscular manifestations in children with severe congenital myopathy due to ACTA1 gene mutations. Neuromuscular disorders : NMD. 2011.07; 21 (7): 489-93. ( PubMed , DOI )

  7. Mitsuhashi S, Ohkuma A, Talim B, Karahashi M, Koumura T, Aoyama C, Kurihara M, Quinlivan R, Sewry C, Mitsuhashi H, Goto K, Koksal B, Kale G, Ikeda K, Taguchi R, Noguchi S, Hayashi YK, Nonaka I, Sher RB, Sugimoto H, Nakagawa Y, Cox GA, Topaloglu H, Nishino I: A congenital muscular dystrophy with mitochondrial structural abnormalities caused by defective de novo phosphatidylcholine biosynthesis. American journal of human genetics. 2011.06; 88 (6): 845-851. ( PubMed , DOI )

  8. Nomura W, Ohashi N, Okuda Y, Narumi T, Ikura T, Ito N, Tamamura H: Fluorescence-quenching screening of protein kinase C ligands with an environmentally sensitive fluorophore. Bioconjug Chem. 2011.05; 22 (5): 923-930. ( PubMed , DOI )

  9. Satoshi Uchida, Keiji Itaka, Qixian Chen, Kensuke Osada, Kanjiro Miyata, Takehiko Ishii, Mariko Harada-Shiba, Kazunori Kataoka: Combination of chondroitin sulfate and polyplex micelles from Poly (ethylene glycol)-poly {N’-[N-(2-aminoethyl)-2-aminoethyl] aspartamide} block copolymer for prolonged in vivo gene transfection with reduced toxicity Journal of Controlled Release. 2011.05; 155 (2): 296-302. ( DOI )

  10. Kazuki Takeda, Takuro Hayashi, Tetsuya Abe, Yu Hirano, Yuya Hanazono, Masafumi Yohda, Kunio Miki: Dimer structure and conformational variability in the N-terminal region of an archaeal small heat shock protein, StHsp14.0. J Struct Biol. 2011.04; 174 (1): 92-99. ( PubMed , DOI )

  11. Prakash T, Oshima K, Morita H, Fukuda S, Imaoka A, Kumar N., Sharma VK, Takahashi M, Saitou N, Taylor TD, Ohno H, Umesaki Y, Hattori M: Complete genome sequences of rat and mouse segmented filamentous bacteria, a potent inducer of Th17 cell differentiation Cell Host & Microbe. 2011;

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  6. 二階堂 愛: 【1細胞解析-技術と応用】技術　1細胞トランスクリプトームデータの解析技術 医学のあゆみ. 2021.03; 276 (10): 961-966. ( 医中誌 )

  7. 高地 雄太: 免疫関連疾患のゲノミクス研究の現在　自己免疫疾患のゲノム解析　ゲノム精密医療に向けて 日本リウマチ学会総会・学術集会プログラム・抄録集. 2021.03; 65回 173. ( 医中誌 )

  8. 二階堂愛: 1細胞トランスクリプトームデータの解析技術 医学のあゆみ. 2021.03;

  9. 棚谷 綾, 吉岡 千咲, 増野 弘幸, 森 修一, 伊藤 暢聡, 影近 弘之, 平田 尚也, 諫田 泰成: リトコール酸をリードとしたビタミンD誘導体の構造展開 ビタミン. 2021.03; 95 (3): 100-101. ( 医中誌 )

  10. 村上 賢, 山嵜 博未, 林 康貴, 井上 大地: 【骨髄異形成症候群の最新の知見】クローン性造血とMDS Medical Science Digest. 2021.02; 47 (2): 88-91. ( 医中誌 )

  1. 高地 雄太: 専門医のためのアレルギー学講座　遺伝子から見た免疫・アレルギー　免疫細胞のトランスクリプトーム解析と疾患感受性遺伝子　eQTLとGWASの統合解析 アレルギー. 2020.12; 69 (10): 947-951. ( 医中誌 )

  2. 太田 峰人, 永渕 泰雄, 波多野 裕明, 石垣 和慶, 竹島 雄介, 柳岡 治先, 小林 聖未, 大久保 麻衣, 杉森 祐介, 前田 淳子, 中野 正博, 山田 紗依子, 吉田 良知, 岩崎 由希子, 住友 秀次, 庄田 宏文, 高地 雄太, 山本 一彦, 岡村 僚久, 藤尾 圭志: 機能ゲノム解析による全身性免疫疾患へのアプローチ 日本臨床免疫学会総会プログラム・抄録集. 2020.10; 48回 76. ( 医中誌 )

  3. 高地 雄太: 【ヒト免疫疾患研究の新たなアプローチ】ヒト免疫疾患のゲノム解析からのアプローチ　多因子遺伝疾患 炎症と免疫. 2020.10; 28 (6): 460-464. ( 医中誌 )

  4. 高地 雄太: 病態探索に挑む　Splicing QTL解析を介した免疫疾患の病態へのアプローチ 日本臨床免疫学会総会プログラム・抄録集. 2020.10; 48回 47. ( 医中誌 )

  5. 二階堂 愛: ヒト細胞アトラス構築のための1細胞トランスクリプトーム技術 日本臨床免疫学会総会プログラム・抄録集. 2020.10; 48回 82. ( 医中誌 )

  6. 尾堀 佐知子, 三橋 里美, 松本 直通: 【Long read sequencer】長鎖シークエンサーを用いたヒト疾患解析 遺伝子医学. 2020.07; 10 (3): 23-28. ( 医中誌 )

  7. 二階堂 愛: Quartz-Seq2　ヒト細胞アトラス時代の高精度1細胞RNAシーケンス法 再生医療. 2020.05; 19 (2): 138-141. ( 医中誌 )

  8. 吉原 綾菜, 吉岡 千咲, 川崎 波留, 増野 弘幸, 河内 恵美子, 諫田 泰成, 平田 尚也, 伊藤 暢聡, 影近 弘之, 棚谷 綾: 高いビタミンD活性を有するリトコール酸側鎖誘導体の創製 ビタミン. 2020.04; 94 (4): 287. ( 医中誌 )

  9. 笹川 洋平, 田中 かおり, 林 哲太郎, 二階堂 愛: 1細胞RNA解析で世界最高成績 －国際的な性能比較研究で証明－ 2020.04;

  10. 笹川 洋平, 田中 かおり, 林 哲太郎, 二階堂 愛: 1細胞RNA解析で世界最高成績 －国際的な性能比較研究で証明－ 2020.04;

  11. 高地 雄太: 【特発性炎症性筋疾患update】IIMのゲノム解析の現状 リウマチ科. 2020.04; 63 (4): 369-373. ( 医中誌 )

  12. 高地 雄太: 【ビッグデータ時代のゲノム医学】免疫・アレルギー疾患のゲノム医学　関節リウマチのゲノム医学 生体の科学. 2020.04; 71 (2): 142-146. ( 医中誌 )

  13. 高地 雄太: 整形外科領域におけるゲノム医療:現状と臨床への展開　eQTLを介した関節リウマチのゲノム解析 日本整形外科学会雑誌. 2020.01; 94 (1): 6-10. ( 医中誌 )

  14. Kochi Y: [TRANSCRIPTOME ANALYSIS OF IMMUNE CELLS AND DISEASE SUSCEPTIBLE GENES]. Arerugi = [Allergy]. 2020; 69 (10): 947-951. ( PubMed , DOI )

  1. 二階堂 愛: 【シングルセルゲノミクス　組織の機能、病態が1細胞レベルで見えてきた!】(第3章)技術開発　シングルセルゲノム情報解析の基盤技術 実験医学. 2019.12; 37 (20): 3498-3501. ( 医中誌 )

  2. 二階堂 愛: 【シングルセルゲノミクス　組織の機能、病態が1細胞レベルで見えてきた!】(第3章)技術開発　進歩を続ける1細胞トランスクリプトーム計測法 実験医学. 2019.12; 37 (20): 3491-3496. ( 医中誌 )

  3. 土田 優美, 太田 峰人, 石垣 和慶, 住友 秀次, 山口 健介, 永渕 泰雄, 土屋 遥香, 庄田 宏文, 鈴木 亜香里, 山本 一彦, 高地 雄太, 藤尾 圭志: 刺激下でのCD4陽性T細胞におけるexpression quantitative trait locusの検討 日本臨床免疫学会総会プログラム・抄録集. 2019.10; 47回 122. ( 医中誌 )

  4. 鈴木 亜香里, 高地 雄太, 石垣 和慶, 山本 一彦: 運動器疾患ゲノム研究の未来　統合オミックス解析による関節リウマチ関連遺伝子の同定 日本整形外科学会雑誌. 2019.09; 93 (8): S1609. ( 医中誌 )

  5. 棚谷 綾, 吉岡 千咲, 川崎 波留, 佐々木 晴江, 藤原 葉子, 増野 弘幸, 伊藤 暢聡, 影近 弘之: ビタミンD活性を有するリトコール酸誘導体の構造展開 ビタミン. 2019.08; 93 (8): 370-371. ( 医中誌 )

  6. 高地 雄太: 【システム臨床免疫学】eQTLによる自己免疫疾患の病因解明 炎症と免疫. 2019.08; 27 (5): 398-401. ( 医中誌 )

  7. 林 哲太郎, 二階堂 愛: 生化学・分子生物学　1細胞RNAシーケンス法における遺伝子全長被覆度と網羅度の役割 医学のあゆみ. 2019.07; 270 (3): 258-260. ( 医中誌 )

  8. 堀端 康博, 三橋 里美, 青山 智英子, 清水 裕晶, 杉本 博之: 筋分化におけるホスファチジルコリン輸送タンパク質STARD7の役割の解析 脂質生化学研究. 2019.06; 61 118-120. ( 医中誌 )

  9. 土屋 遥香, 太田 峰人, 住友 秀次, 石垣 和慶, 鈴木 亜香里, 高地 雄太, 土田 優美, 庄田 宏文, 乾 洋, 武冨 修治, 門野 夕峰, 田中 栄, 山本 一彦, 藤尾 圭志: 自己免疫疾患のメカニズムへの最新のアプローチ　関節リウマチ患者由来滑膜線維芽細胞の統合的機能ゲノム解析 日本リウマチ学会総会・学術集会プログラム・抄録集. 2019.03; 63回 202. ( 医中誌 )

  10. 高地 雄太: 自己免疫疾患のメカニズムへの最新のアプローチ　臨床的無筋症性皮膚筋炎におけるWDFY4の役割 日本リウマチ学会総会・学術集会プログラム・抄録集. 2019.03; 63回 203. ( 医中誌 )

  11. 高地 雄太: 【リウマチ性疾患における遺伝素因と環境要因】強皮症および炎症性筋疾患の遺伝素因 リウマチ科. 2019.02; 61 (2): 116-121. ( 医中誌 )

  12. 高地 雄太: 【自己免疫疾患の個別化医療】ゲノム情報による自己免疫疾患の個別化医療 Precision Medicine. 2019.01; 2 (1): 10-13. ( 医中誌 )

  13. 林哲太郎, 二階堂愛: 1細胞RNAシーケンス法における遺伝子全長被覆度と網羅度の役割 医学のあゆみ. 2019; 270 (3): 258-260.

  14. 二階堂愛, 二階堂愛: 進歩を続ける1細胞トランスクリプトーム計測法 実験医学. 2019; 37 (20): 3491-3496.

  15. 二階堂愛, 二階堂愛: シングルセルゲノム情報解析の基盤技術 実験医学. 2019; 37 (20): 3498-3501.

  1. 細江 雄飛, 稲葉 理美, 沼本 修孝, 伊藤 暢聡, 織田 昌幸: SH2ドメインスワップダイマーが与える安定性と機能への影響評価 日本生化学会大会プログラム・講演要旨集. 2018.09; 91回 [1T11e-04(1P. ( 医中誌 )

  2. 沼本 修孝, 赤津 ちづる, 品川 健朗, 鍔田 武志, 伊藤 暢聡: B細胞抑制性因子CD72とSm/RNPの複合体形成様式の推測 日本生化学会大会プログラム・講演要旨集. 2018.09; 91回 [1P-084]. ( 医中誌 )

  3. 二階堂 愛: 新しいゲノム科学と生化学　1細胞トランスクリプトームのための生化学 日本生化学会大会プログラム・講演要旨集. 2018.09; 91回 [2S01a-01]. ( 医中誌 )

  4. 中川 草, 上田 真保子, 中野 雄介, 安田 二朗, 小柳 義夫, 佐藤 佳, 黒崎 陽平: 微生物・感染症学における多様なDry解析アプローチ　公共データベースを活用したエボラウイルスGP遺伝子の感染効率に関与する塩基突然変異の同定 日本獣医学会学術集会講演要旨集. 2018.08; 161回 209. ( 医中誌 )

  5. 二階堂 愛, 林 哲太郎, 尾崎 遼, 梅田 茉奈: JAPANESE AUTHOR シングルセル解析の新たな計測技術を開発 Natureダイジェスト. 2018.05; 15 (5): 22-25.

  6. 石澤 通康, Otero Rocio, 沼本 修孝, 伊倉 貞吉, 伊藤 暢聡, 常盤 広明, Mourino Antonio, 槇島 誠, 山田 幸子: 25-Adamantyl-1α、25-dihydroxyvitamin D3誘導体の組織選択的活性 ビタミン. 2018.04; 92 (4): 232. ( 医中誌 )

  7. 笹川 洋平, 團野 宏樹, 二階堂 愛: (プレスリリース) 数千個の1細胞からRNA量と種類を正確に計測 －細胞機能を網羅的・高精度・低コストに同定可能に－ 2018.03;

  8. 三橋 里美: 【ニューロジェネティクス新時代　次世代シークエンサーが拓く新しい世界】筋疾患・神経疾患のジェネティクス　次世代シークエンサーを用いた筋疾患診断 Clinical Neuroscience. 2018.02; 36 (2): 187-190. ( 医中誌 )

  9. 二階堂 愛: 1細胞トランスクリプトーム技術の最先端 Medical Science Digest. 2018.01; 44 (1): 5-6. ( 医中誌 )

  10. 中川 草, 三橋 里美, Kryukov Kirill, 今西 規: 【どこでも 誰でも より長く　ナノポアシークエンサーが研究の常識を変える!】迅速な細菌種の組成解析 実験医学. 2018.01; 36 (1): 32-37. ( 医中誌 )

  11. 三橋 里美, 中川 草, 上田 真保子, 今西 規, Frith Martin C., 三橋 弘明: 【どこでも 誰でも より長く　ナノポアシークエンサーが研究の常識を変える!】リピート数が関与する疾患の診断に向けて　サブテロメア領域のD4Z4マクロサテライトリピートを読む 実験医学. 2018.01; 36 (1): 44-48. ( 医中誌 )

  12. 落合博, 落合博, 梅田茉奈, 林哲太郎, 芳村美佳, 原田哲仁, 大川恭行, 山本卓, 二階堂愛: マウス胚性幹細胞における遺伝子発現量多様性の制御機構の包括的解析 日本生化学会大会(Web). 2018; 91st [3S08m-03].

  1. 上田 真保子, 三橋 里美, 三橋 弘明, 今西 規, 中川 草: 細胞融合にかかわる内在性レトロウイルス由来遺伝子の同定 生命科学系学会合同年次大会. 2017.12; 2017年度 [3P-1463]. ( 医中誌 )

  2. 佐藤 海, 大友 麻子, 上田 真保子, 杉山 純也, 小野 鈴花, 三井 駿, 中川 草, 秦野 伸二: N末端自己相互作用ドメインのALS2疾患原因変異は、ALS2の正常な多量体形成やエンドソーム局在を阻害する 生命科学系学会合同年次大会. 2017.12; 2017年度 [3P-1120]. ( 医中誌 )

  3. 飯田 剛, 神山 淳, 名越 慈人, 辻 収彦, 二階堂 愛, 佐野坂 司, 西村 空也, 小林 喜臣, 松本 守雄, 岡野 栄之, 中村 雅也: 脊髄損傷に対する細胞移植治療　安全かつ有効なヒトiPS細胞由来神経幹細胞の条件 日本整形外科学会雑誌. 2017.08; 91 (8): S1587. ( 医中誌 )

  4. 梅田 茉奈, 林 哲太郎, 笹川 洋平, 二階堂 愛: 効果的なstranded RNA-Seq用ライブラリー調製キット 選定評価試験 ～ Embryonic stem cel（l ES cell）およびPrimitive endoderm cel（l PrE cell） を用いたrRNA depletion RNA-Seq ～ Application Note NIPPON Genetics. 2017.07;

  5. Ikura T., Ito N.: Functional conversion from peptydyl-prolyl isomerase to protease by a single amino acid substitution EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2017.07; 46 S162.

  6. 三橋 里美, 松本 直通: 【精神科におけるてんかん診療】てんかんの遺伝と遺伝子診断 臨床精神医学. 2017.07; 46 (7): 843-847. ( 医中誌 )

  7. 松本 拡高, 二階堂 愛: 【日常化するシングルセル遺伝子発現解析】網羅的な1細胞発現から知識を取り出すデータ解析技術の新展開 細胞. 2017.05; 49 (6): 273-276. ( 医中誌 )

  8. 二階堂 愛: 微量サンプルを用いたオミックス解析　RamDA-seq　あらゆるRNAの完全長を捉える1細胞total RNAシーケンス法 日本細胞生物学会大会講演要旨集. 2017.05; 69回 24. ( 医中誌 )

  9. 棚谷 綾, 佐々木 晴江, 川崎 波留, 増野 弘幸, 河内 恵美子, 伊藤 暢聡, 石田 寛明, 山本 恵子, 平野 真梨子, 影近 弘之: 高いビタミンD活性を有するリトコール酸誘導体の創製 ビタミン. 2017.04; 91 (4): 301. ( 医中誌 )

  10. 團野 宏樹, 二階堂 愛: 実験講座　1細胞トランスクリプトーム解析の高出力化と自動化 生体の科学. 2017.04; 68 (2): 178-184. ( 医中誌 )

  11. 三橋 里美: 【ミオパチー:最近のトピックス】顔面肩甲上腕型筋ジストロフィー 神経内科. 2017.03; 86 (3): 342-345. ( 医中誌 )

  12. 三橋 里美: 【筋肉研究の最前線】次世代シークエンサー(NGS)を用いた筋疾患診断 Clinical Calcium. 2017.02; 27 (3): 401-408. ( 医中誌 )

  13. Mitsuhashi S: [Diagnosis for skeletal muscle disorders using next-generation sequencing.] Clinical calcium. 2017; 27 (3): 401-408. ( PubMed , DOI )

  14. 飯田剛, 神山淳, 名越慈人, 辻収彦, 二階堂愛, 佐野坂司, 西村空也, 小林喜臣, 松本守雄, 岡野栄之, 中村雅也: 脊髄損傷に対する細胞移植治療-安全かつ有効なヒトiPS細胞由来神経幹細胞の条件- 日本整形外科学会雑誌. 2017; 91 (8): S1587.

  15. 二階堂愛: RamDA-seq:あらゆるRNAの完全長を捉える1細胞total RNAシーケンス法 日本細胞生物学会大会(Web). 2017; 69th 24.

  16. 二階堂愛: RamDA-seq:あらゆるRNAの全長を1細胞レベルで検出するRNAシーケンス法 日本生化学会大会(Web). 2017; 90th [2AS14-2].

  17. 團野宏樹, 笹川洋平, 二階堂愛: 高出力1細胞トランスクリプトーム解析の展開と多細胞生物学 日本生化学会大会(Web). 2017; 90th [3AW05-7].

  18. 林哲太郎, 尾崎遼, 笹川洋平, 團野宏樹, 梅田茉奈, 二階堂愛: 1細胞トータルRNAシーケンス法は,発生生物学の「ゆらぎ」解析にパラダイムシフトをもたらすのか? 日本生化学会大会(Web). 2017; 90th [3PW15-1].

  1. 三橋 里美, 西野 一三: 【筋ジストロフィー・筋疾患-最近の進歩】ミオパチーの臨床と研究の最新トピックス　次世代シークエンサーによる筋疾患の診断 医学のあゆみ. 2016.10; 259 (1): 45-49. ( 医中誌 )

  2. 三橋 里美: 【筋ジストロフィーup to date】各病型の特徴と診断のポイント　顔面肩甲上腕型筋ジストロフィー Clinical Neuroscience. 2016.03; 34 (3): 328-329. ( 医中誌 )

  3. 林 哲太郎, 二階堂 愛: １細胞採取法としてのフローサイトメトリーと関連技術-１細 胞遺伝子発現解析の観点から 実験医学別冊「新版 フローサイトメトリー もっと幅広く使いこなせる！」. 2016; 267-274.

  4. 林 哲太郎, 二階堂 愛: 「フローサイトメーターを用いた１細胞遺伝子発現解析の実際 実験医学別冊「新版 フローサイトメトリー もっと幅広く使いこなせる！」. 2016; 275-283.

  5. 二階堂愛: 超高精度1細胞RNA-seqを実現する生化学 日本生化学会大会(Web). 2016; 89th [2S03-4].

  1. 三橋 里美: 【骨格筋症候群(第2版)-その他の神経筋疾患を含めて-】[上]　筋ジストロフィーおよび膜イオンチャネル異常症　先天性筋ジストロフィー(CMD)　非福山型先天性筋ジストロフィー　巨大ミトコンドリア先天性筋ジストロフィー(コリンキナーゼβ欠損症) 日本臨床. 2015.05; 別冊 (骨格筋症候群(上)): 173-176. ( 医中誌 )

  2. 埜中 征哉, 辻野 精一, 三橋 里美, 西野 一三: 日本におけるPompe病の現状と臨床病理学的特徴 神経内科. 2015.05; 82 (5): 537-545. ( 医中誌 )

  3. 三橋 里美, 西野 一三: 【ますます臨床利用が進む遺伝子検査-その現状と今後の展開そして課題-】(第3章)生殖細胞系列遺伝学的検査の臨床応用　各種疾患における診療目的の遺伝学的検査　筋疾患の遺伝学的検査 遺伝子医学MOOK. 2015.04; (28): 136-140. ( 医中誌 )

  4. 露崎弘毅, 師田郷太, 師田郷太, 石井学, 仲里猛留, 宮崎智, 二階堂愛: 文献注釈情報MeSHを利用した網羅的な遺伝子の機能アノテーションパッケージ 日本生化学会大会(Web). 2015; 88th [3W24-3].

  5. 二階堂愛: ncRNA研究をはじめよう 3. 1細胞からのlncRNAの網羅的計測 実験医学. 2015; 33 (20): 3385-3389.

  6. 二階堂愛: Quartz-Seq RamDAによる非ポリA mRNAの1細胞発現解析 日本生化学会大会(Web). 2015; 88th [2W16-5].

  1. 木村 円, 中村 治雅, 三橋 里美, 竹内 芙実, 森 まどか, 清水 玲子, 小牧 宏文, 林 由起子, 西野 一三, 川井 充, 武田 伸一: 今開かれる筋ジストロフィー治療の扉　筋ジストロフィーの臨床開発を推進する研究基盤　RemudyとMDCTN 臨床神経学. 2014.12; 54 (12): 1069-1070. ( 医中誌 )

  2. Kimura E, Nakamura H, Mitsuhashi S, Takeuchi F, Mori-Yoshimura M, Shimizu R, Komaki H, Hayashi YK, Nishino I, Kawai M, Takeda S: [Infrastructure for the clinical research of muscular dystrophies: remudy and MDCTN]. Rinsho shinkeigaku = Clinical neurology. 2014; 54 (12): 1069-70. ( PubMed , DOI )

  3. 二階堂愛: 1細胞からすべてのRNAを計測するシーケンス技術の現在と展望 日本生化学会大会(Web). 2014; 87th [1S05p-5].

  1. 二階堂 愛: NGS現場の会 第三回研究会開催にあたって 次世代シークエンサーのその先に : シークエンス技術の現在と未来を考える 細胞工学. 2013; 32 (8): 893-897.

  1. 齊藤 祐子, 塩谷 彩子, 池田 謙輔, 青天目 信, 三橋 里美: 【病理解剖マニュアル】(第1部)病理解剖の進め方、切り出し方法など　特殊な部位、手技、検体保存　末梢神経、筋 病理と臨床. 2012.04; 30 (臨増): 69-76. ( 医中誌 )

  1. 佐野 雅己, 藤本 仰一, 小林 徹也, 二階堂 愛, ート作成者: パネルディスカッション (差異・パターン形成と拡散方程式の現在)(生物学的時間とスケール変換) (離散力学系の分子細胞生物学への応用数理) 数理解析研究所講究録. 2010.07; 1698 51-54.

  2. 二階堂愛, 愛, ノート作成: パネルディスカッション : まとめ (離散力学系の分子細胞生物学への応用数理) 数理解析研究所講究録. 2010.07; 1698 232-236.

  3. 近藤 滋, 二階堂愛, 愛, ート作成: 話題提供「生物学における理論の有用性」 (進化とネットワーク) (離散力学系の分子細胞生物学への応用数理) 数理解析研究所講究録. 2010.07; 1698 152-161.

  4. 泰地 真弘人, 二階堂 愛, ノ: パネルディスカッション (タンパク質構造と進化と情報幾何) (離散力学系の分子細胞生物学への応用数理) 数理解析研究所講究録. 2010.07; 1698 229-231.

  5. 青山 智英子, 三橋 里美, 杉本 博之, 西野 一三: コリンキナーゼβノックアウトマウスの解析とヒト疾患における検討 脂質生化学研究. 2010.05; 52 85-87. ( 医中誌 )

  6. 三橋 里美, 川井 充: 【神経内科の病気のすべて】末梢神経疾患・筋疾患　筋疾患の分類と診断 からだの科学. 2010.05; (265): 174-179. ( 医中誌 )

  7. 二階堂愛: 遺伝子発現とChIP-seqデータの統合による転写制御ネットワークの同定 生化学. 2010; 83回・33回 1W20-4.

  1. 三橋 里美, 梁 文貞, 西野 一三: 【筋病理　最近の進歩】代謝性ミオパチーの筋病理 神経内科. 2009.10; 71 (4): 369-376. ( 医中誌 )

  2. 三橋 里美, 西野 一三: 代謝性ミオパチーの最近の話題 小児科. 2009.05; 50 (5): 603-609. ( 医中誌 )

  3. 三橋 里美, 埜中 征哉, 西野 一三: 【糖原病II型(Pompe病)　診断から治療へ】糖原病II型(Pompe病)の診断へのアプローチ　病理診断 神経内科. 2009.05; 70 (5): 434-436. ( 医中誌 )

  4. Ikura Teikichi, Kinoshita Kengo, Ito Nobutoshi: [Correlation between structure and function of peptidyl-prolyl isomerase]. Tanpakushitsu Kakusan Koso. 2009.02; 54 (2): 167-172. ( PubMed )

  1. Nakamura Haruki, Ito Nobutoshi, Kusunoki Masami: [Development of PDBj: Advanced database for protein structures]. Tanpakushitsu Kakusan Koso. 2002.06; 47 (8 Suppl): 1097-1101. ( PubMed )

  1. Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia 2022.06; 140 (8): 875-888. ( DOI )

  1. 二階堂愛, 二階堂愛: 超多検体オミクスによる細胞特性の計測 日本再生医療学会総会(Web). 2021; 20th

  1. 大川真澄, 大川真澄, 佐藤天平, 林哲太郎, 二階堂愛, 二階堂愛, 二階堂愛: マウス小腸における老化が細胞構成比および遺伝子に与える影響とその領域特異性 日本分子生物学会年会プログラム・要旨集(Web). 2020; 43rd

  2. 亀田健, 亀田健, 鈴木美穂, 二階堂愛, 粟津暁紀, 冨樫祐一, 冨樫祐一: DNAの化学修飾と遺伝子発現制御 システム制御情報学会研究発表講演会講演論文集(CD-ROM). 2020; 64th

  3. 森田梨津子, 三千典子, 佐々木弘子, 林哲太郎, 梅田茉奈, 芳村美佳, 山本尚貴, 柴田達夫, 阿部高也, 清成寛, 古田泰秀, 古田泰秀, 二階堂愛, 二階堂愛, 藤原裕展: 毛包幹細胞の発生起源と誘導過程 日本分子生物学会年会プログラム・要旨集(Web). 2020; 43rd

  4. 高田仁実, 笹川洋平, 芳村美佳, 田中かおり, 二階堂愛, 栗崎晃: 胃の恒常性維持を司る幹細胞分化制御機構の解析 日本分子生物学会年会プログラム・要旨集(Web). 2020; 43rd

  5. 二階堂愛: ヒト細胞アトラス時代の高出力1細胞RNA-seq解析技術 日本再生医療学会総会(Web). 2020; 19th

  1. ALPHLARD-NT: Bayesian Method for Human Leukocyte Antigen Genotyping and Mutation Calling through Simultaneous Analysis of Normal and Tumor Whole-Genome Sequence Data 2019.09; 26 (9): 923-937. ( DOI )

  2. 石原悟, 笹川洋平, 亀田健, 亀田健, 山下隼人, 琴村直恵, 阿部真之, 下野洋平, 二階堂愛: 転写開始点でのクロマチンの部分凝集は遺伝子の転写量と負の相関を示す 日本分子生物学会年会プログラム・要旨集(Web). 2019; 42nd

  1. ALPHLARD: a Bayesian method for analyzing HLA genes from whole genome sequence data 2018.11; 19 (1): ( DOI )

  2. 林哲太郎, 梅田茉奈, 尾崎遼, 笹川洋平, 二階堂愛: RamDA-seqがもたらす1細胞RNAシーケンス法の新たな展望 日本分子生物学会年会プログラム・要旨集(Web). 2018; 41st

  3. 石原悟, 笹川洋平, 琴村直恵, 山下隼人, 山下隼人, 鏡裕行, 阿部真之, 二階堂愛: ヌクレオソーム間での会合の違いでクロマチンを分画する 日本分子生物学会年会プログラム・要旨集(Web). 2018; 41st

  4. 笹川洋平, 田中かおり, 二階堂愛: 高出力型1細胞RNA-seq法Quartz-Seq2の開発と超多検体への応用 日本分子生物学会年会プログラム・要旨集(Web). 2018; 41st

  5. 二階堂愛: 細胞集団の不均質性を1細胞・全遺伝子解像度で高速で高精度に測定するオミクス技術 日本再生医療学会総会(Web). 2018; 17th

  6. 小林英城, 長濱統彦, 荒井渉, 笹川洋平, 梅田茉奈, 林哲太郎, 二階堂愛, 渡部裕美, 小栗一将, 北里洋, 藤岡勘太郎, 木戸ゆかり, 高見英人: 超深海性ヨコエビ,カイコウオオソコエビの糖質分解酵素遺伝子の解析 日本生物工学会大会講演要旨集. 2018; 70th

  7. 二階堂愛: 1細胞トランスクリプトームのための生化学 日本生化学会大会(Web). 2018; 91st

  1. 二階堂愛: RamDA-seq:Pre-mRNA/ncRNAの全長を1細胞レベルで検出するRNAシーケンス法 日本核酸医薬学会年会講演要旨集. 2017; 3rd

  2. 二階堂愛: RamDA-seq:1細胞完全長Total RNAシーケンス法 日本人類遺伝学会大会プログラム・抄録集. 2017; 62nd

  3. 小林英城, 荒井渉, 高見秀人, 笹川洋平, 梅田茉奈, 林哲太郎, 二階堂愛: 超深海性ヨコエビが保有する多糖分解酵素の遺伝子解析 ブルーアース要旨集. 2017; 2017

  1. 二階堂愛: 亜集団特異的発現マーカーを1細胞・全遺伝子解像度で探索するためのRNAシーケンス技術 再生医療. 2016; 15

  2. 林誠, 林誠, 岩崎佳子, 海老澤昌史, 芳村美佳, 林哲太郎, 笹川洋平, 二階堂愛, 吉崎悟朗: 1細胞RNAseqを用いた魚類精原幹細胞マーカーの探索 日本水産学会大会講演要旨集. 2016; 2016

  3. 笹川洋平, 海老澤昌史, 團野宏樹, 林哲太郎, 二階堂愛: セルソーターを用いたハイスループット1細胞RNA-seq法Quartz-Seq2の開発 日本分子生物学会年会プログラム・要旨集(Web). 2016; 39th

  4. 六峰弘晃, 六峰弘晃, 二階堂愛, 内匠透, 三澤日出巳: アンジェルマン症候群モデルマウスの大脳皮質におけるRNA-seq解析 日本分子生物学会年会プログラム・要旨集(Web). 2016; 39th

  5. 二階堂愛: 生命科学研究を加速するためのAIを計測と計算の融合から考える 第15回産総研・産技連LS-BT合同研究発表会要旨集,2016. 2016;

  6. 林哲太郎, 笹川洋平, 尾崎遼, 團野宏樹, 梅田茉奈, 二階堂愛: RamDA-seq:完全長を捉える新規1細胞トータルRNAシーケンス法 日本分子生物学会年会プログラム・要旨集(Web). 2016; 39th

  1. Sasagawa Y, Nikaido I, Hayashi T, Danno H, Uno KD, Imai T, Ueda HR: Quartz-Seq: a highly reproducible and sensitive single-cell RNA sequencing method, reveals non-genetic gene-expression heterogeneity. Genome Biology. 2013.04; 14 (4): R31. ( PubMed , DOI )

  2. 二階堂愛, 笹川洋平: 1細胞RNA-Seqを用いた幹細胞の細胞状態ゆらぎの理解に向けて 日本分子生物学会年会プログラム・要旨集(Web). 2013; 36th

  1. 水野洋介, 二階堂愛, 岡崎康司: マイクロアレイを用いた生活習慣病関連遺伝子の解明-発現マッピングとeQTLマッピングの可能性- 遺伝子医学MOOK DNAチップ/マイクロアレイ臨床応用の実際 (メディカル ドゥ). 2008.06; (10): 228-233.

  2. 山下泉, 八木研, 水野洋介, 徳澤佳美, 二階堂愛, 仲地豊, 八塚由紀子, 二宮裕一, 坊農秀雅, 須田立雄, 岡崎康司: Id4は骨芽細胞分化と脂肪細胞分化のクロストークを制御する因子である 生化学. 2008;

  1. 二階堂愛, 美野輪治, 八木研, 桜庭喜行, 坊農秀雅, 権藤洋一, 野田哲生, 城石俊彦, 林崎良英, 岡崎康司: 肝臓トランスクリプトームと血清脂質マーカーの情報を統合した連鎖解析による疾患遺伝子の発見 日本分子生物学会年会講演要旨集. 2005; 28th

  1. 仲地豊, 二階堂愛, 八木研, 登内未緒, 坊農秀雅, 岡崎康司: ChIP on chipによるゲノムスケールでの転写因子結合領域探索の試み 日本分子生物学会年会プログラム・講演要旨集. 2004; 27th

  2. 八木研, 近藤大輔, 二階堂愛, 加野浩一郎, 岡崎康司: 成熟脂肪細胞由来の前駆脂肪細胞株DFAT-D1の樹立 日本分子生物学会年会プログラム・講演要旨集. 2004; 27th

  3. 二階堂愛, 八木研, 坊農秀雅, 岡崎康司: ジェネティクスとトランスクリプトームの統合による脂質代謝の遺伝子ネットワークの解明 日本分子生物学会年会プログラム・講演要旨集. 2004; 27th

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