病態制御科学研究部門

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  1. Homma H, Ngo KX, Yoshioka Y, Tanaka H, Inotsume M, Fujita K, Ando T, Okazawa H: PQBP3/NOL7 is an intrinsically disordered protein. Biochem Biophys Res Commun. 2024.12; 736 150453. ( PubMed , DOI )

  2. Tsumaki K, Bertens CJF, Nakayama M, Kato S, Jonao Y, Kuribayashi A, Sato K, Ishiyama S, Asakawa M, Aihara R, Yoshioka Y, Homma H, Tanaka H, Fujita K, Okazawa H, Sone M: Loss of function of VCP/TER94 causes neurodegeneration. Dis Model Mech. 2024.12; 17 (12): dmm050359. ( PubMed , DOI )

  3. Koyano F, Yamano K, Hoshina T, Kosako H, Fujiki Y, Tanaka K, Matsuda N: AAA+ ATPase chaperone p97/VCP(FAF2) governs basal pexophagy. Nature communications. 2024.10; 15 (1): 9347. ( PubMed , DOI )

  4. Yoshioka Y, Huang Y, Jin X, Ngo KX, Kumaki T, Jin M, Toyoda S, Takayama S, Inotsume M, Fujita K, Homma H, Ando T, Tanaka H, Okazawa H: PQBP3 prevents senescence by suppressing PSME3-mediated proteasomal Lamin B1 degradation. EMBO J. 2024.09; 43 (18): 3968-3999. ( PubMed , DOI )

  5. Endo R, Kinefuchi H, Sawada M, Kikuchi R, Kojima W, Matsuda N, Yamano K: TBK1 adaptor AZI2/NAP1 regulates NDP52-driven mitochondrial autophagy. The Journal of biological chemistry. 2024.09; 300 (10): 107775. ( PubMed , DOI )

  6. Akiyama M, Kanayama M, Umezawa Y, Nagao T, Izumi Y, Yamamoto M, Ohteki T: An early regulatory mechanism of hyperinflammation by restricting monocyte contribution. Frontiers in immunology. 2024.07; 15 1398153. ( PubMed , DOI )

  7. Akiyama M, Kanayama M, Umezawa Y, Nagao T, Izumi Y, Yamamoto M, Ohteki T.: An early regulatory mechanism of hyperinflammation by restricting monocyte contribution Front Immunol.. 2024.07; 15 1398153.

  8. Aiko Watanabe, Fumika Koyano, Kenichiro Imai, Yohei Hizukuri, Shizuka Ogiwara, Tomoya Ito, Jun Miyamoto, Chihiro Shibuya, Mayumi Kimura, Kazuya Toriumi, Chie Motono, Makoto Arai, Keiji Tanaka, Yoshinori Akiyama, Koji Yamano, Noriyuki Matsuda: The origin of esterase activity of Parkinson's disease causative factor DJ-1 implied by evolutionary trace analysis of its prokaryotic homolog HchA. J Biol Chem. 2024.06; 300 (7): 107476. ( PubMed , DOI )

  9. Manabu S, Nawa N, Noguchi Y, Taki A, Kashimada A, Honda I, Koyama A, Okazaki K, Kondo M, Miyahara H, Ito K, Yamauchi T, Kondo T, Honda-Ozaki F, Kusuda S, Morioka C, Fujiwara T, Morio T, Kashimada K: Stage III Chorioamnionitis Is Associated with Reduced Risk of Severe Retinopathy of Prematurity. The Journal of pediatrics. 2024.05; 114085. ( PubMed , DOI )

  10. Homma H, Yoshioka Y, Fujita K, Shirai S, Hama Y, Komano H, Saito Y, Yabe I, Okano H, Sasaki H, Tanaka H, Okazawa H: Dynamic molecular network analysis of iPSC-Purkinje cells differentiation delineates roles of ISG15 in SCA1 at the earliest stage. Commun Biol. 2024.04; 7 (1): 413. ( PubMed , DOI )

  11. Yamano K, Kinefuchi H, Kojima W: Mitochondrial lipid dynamics regulated by MITOL-mediated ubiquitination. Journal of biochemistry. 2024.03; 175 (3): 217-219. ( PubMed , DOI )

  12. Homma H, Tanaka H, Fujita K, Okazawa H: Necrosis Links Neurodegeneration and Neuroinflammation in Neurodegenerative Disease. Int J Mol Sci. 2024.03; 25 (7): 3636. ( PubMed , DOI )

  13. Kamii Y, Hayashizaki K, Kanno T, Chiba A, Ikegami T, Saito M, Akeda Y, Ohteki T, Kubo M, Yoshida K, Kawakami K, Oishi K, Araya J, Kuwano K, Kronenberg M, Endo Y, Kinjo Y.: IL-27 regulates the differentiation of follicular helper NKT cells via metabolic adaptation of mitochondria. Proc Natl Acad Sci USA.. 2024.02; 121 e2313964121.

  14. Ohara D, Takeuchi Y, Watanabe H, Lee Y, Mukoyama H, Ohteki T, Kondoh G, Hirota K.: Notch2 with retinoic acid license IL-23 expression by intestinal EpCAM+ DCIR2+ cDC2s in mice J Exp Med.. 2024.02; 221 e20230923.

  15. Cui M, Yamano K, Yamamoto K, Yamamoto-Imoto H, Minami S, Yamamoto T, Matsui S, Kaminishi T, Shima T, Ogura M, Tsuchiya M, Nishino K, Layden BT, Kato H, Ogawa H, Oki S, Okada Y, Isaka Y, Kosako H, Matsuda N, Yoshimori T, Nakamura S: HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence. Proceedings of the National Academy of Sciences of the United States of America. 2024.01; 121 (2): e2306454120. ( PubMed , DOI )

  16. Yamano K, Sawada M, Kikuchi R, Nagataki K, Kojima W, Endo R, Kinefuchi H, Sugihara A, Fujino T, Watanabe A, Tanaka K, Hayashi G, Murakami H, Matsuda N: Optineurin provides a mitophagy contact site for TBK1 activation. The EMBO journal. 2024.01; 43 (5): 754-779. ( PubMed , DOI )

  17. Kawasaki I, Sugiura K, Sasaki T, Matsuda N, Sato M, Sato K: MARC-3, a membrane-associated ubiquitin ligase, is required for fast polyspermy block in Caenorhabditis elegans. Nature communications. 2024.01; 15 (1): 792. ( PubMed , DOI )

  18. Miyamoto T, Izawa K, Masui S, Yamazaki A, Yamasaki Y, Matsubayashi T, Shiraki M, Ohnishi H, Yasumura J, Tomohiro K, Miyamae T, Matsubara T, Arakawa N, Ishige T, Takizawa T, Shimbo A, Shimizu M, Kimura N, Maeda Y, Maruyama Y, Shigemura T, Furuta J, Sato S, Tanaka H, Izumikawa M, Yamamura M, Hasegawa T, Kaneko H, Nakagishi Y, Nakano N, Iida Y, Nakamura T, Wakiguchi H, Hoshina T, Kawai T, Murakami K, Akizuki S, Morinobu A, Ohmura K, Eguchi K, Sonoda M, Ishimura M, Furuno K, Kashiwado M, Mori M, Kawahata K, Hayama K, Shimoyama K, Sasaki N, Ito T, Umebayashi H, Omori T, Nakamichi S, Dohmoto T, Hasegawa Y, Kawashima H, Watanabe S, Taguchi Y, Nakaseko H, Iwata N, Kohno H, Ando T, Ito Y, Kataoka Y, Saeki T, Kaneko U, Murase A, Hattori S, Nozawa T, Nishimura K, Nakano R, Watanabe M, Yashiro M, Nakamura T, Komai T, Kato K, Honda Y, Hiejima E, Yonezawa A, Bessho K, Okada S, Ohara O, Takita J, Yasumi T, Nishikomori R, Japan CAPS working group: Clinical characteristics of cryopyrin-associated periodic syndrome and long-term real-world efficacy and tolerability of canakinumab in Japan: results of a nationwide survey. Arthritis & rheumatology (Hoboken, N.J.). 2024.01; ( PubMed , DOI )

  1. Yamano K, Kinefuchi H, Kojima W: Mitochondrial quality control via organelle and protein degradation. Journal of biochemistry. 2023.12; ( PubMed , DOI )

  2. Yoshioka Y, Taniguchi JB, Homma H, Tamura T, Fujita K, Inotsume M, Tagawa K, Misawa K, Matsumoto N, Nakagawa M, Inoue H, Tanaka H, Okazawa H: AAV-mediated editing of PMP22 rescues Charcot-Marie-Tooth disease type 1A features in patient-derived iPS Schwann cells. Commun Med (Lond). 2023.11; 3 (1): 170. ( PubMed , DOI )

  3. Gall-Duncan T, Luo J, Jurkovic CM, Fischer LA, Fujita K, Deshmukh AL, Harding RJ, Tran S, Mehkary M, Li V, Leib DE, Chen R, Tanaka H, Mason AG, Lévesque D, Khan M, Razzaghi M, Prasolava T, Lanni S, Sato N, Caron MC, Panigrahi GB, Wang P, Lau R, Castel AL, Masson JY, Tippett L, Turner C, Spies M, La Spada AR, Campos EI, Curtis MA, Boisvert FM, Faull RLM, Davidson BL, Nakamori M, Okazawa H, Wold MS, Pearson CE: Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability. Cell. 2023.10; 186 (22): 4898-4919.e25. ( PubMed , DOI )

  4. Shinya Abe, Takuma Asahi, Takahiro Hara, Guangwei Cui, Akihiro Shimba, Shizue Tani-Ichi, Kohei Yamada, Kazuko Miyazaki, Hitoshi Miyachi, Satsuki Kitano, Naotoshi Nakamura, Junichi Kikuta, Alexis Vandenbon, Masaki Miyazaki, Ryo Yamada, Toshiaki Ohteki, Masaru Ishii, Veronika Sexl, Takashi Nagasawa, Koichi Ikuta: Hematopoietic cell-derived IL-15 supports NK cell development in scattered and clustered localization within the bone marrow. Cell Rep. 2023.09; 42 (9): 113127. ( PubMed , DOI )

  5. Fujita K, Homma H, Jin M, Yoshioka Y, Jin X, Saito Y, Tanaka H, Okazawa H: Mutant α-synuclein propagates via the lymphatic system of the brain in the monomeric state. Cell Rep. 2023.08; 42 (8): 112962. ( PubMed , DOI )

  6. Shiwaku H, Katayama S, Gao M, Kondo K, Nakano Y, Motokawa Y, Toyoda S, Yoshida F, Hori H, Kubota T, Ishikawa K, Kunugi H, Ikegaya Y, Okazawa H, Takahashi H: Analyzing schizophrenia-related phenotypes in mice caused by autoantibodies against NRXN1α in schizophrenia. Brain Behav Immun. 2023.07; 111 32-45. ( PubMed , DOI )

  7. Kurusu R, Fujimoto Y, Morishita H, Noshiro D, Takada S, Yamano K, Tanaka H, Arai R, Kageyama S, Funakoshi T, Komatsu-Hirota S, Taka H, Kazuno S, Miura Y, Koike M, Wakai T, Waguri S, Noda NN, Komatsu M: Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex. Developmental cell. 2023.07; 58 (13): 1189-1205.e11. ( PubMed , DOI )

  8. Ziegler-Heitbrock L, Ohteki T, Ginhoux F, Shortman K, Spits H.: Reply to 'Reclassifying plasmacytoid dendritic cells as innate lymphocytes is premature'. Nat Rev Immunol. 2023.05; 23 (5): 338-339.

  9. Akabane S, Watanabe K, Kosako H, Yamashita SI, Nishino K, Kato M, Sekine S, Kanki T, Matsuda N, Endo T, Oka T: TIM23 facilitates PINK1 activation by safeguarding against OMA1-mediated degradation in damaged mitochondria. Cell reports. 2023.05; 42 (5): 112454. ( PubMed , DOI )

  10. Masashi Kanayama, Yuta Izumi, Megumi Akiyama, Toyoki Hayashi, Koji Atarashi, Axel Roers, Taku Sato, Toshiaki Ohteki: Myeloid-like B cells boost emergency myelopoiesis through IL-10 production during infection. J Exp Med. 2023.04; 220 (4): e20221221. ( PubMed , DOI )

  11. Aiko Watanabe, Hiroyuki Koike, Naoki Kumagami, Shigeki Shimba, Ichiro Manabe, Yumiko Oishi: Arntl deficiency in myeloid cells reduces neutrophil recruitment and delays skeletal muscle repair. Scientific Reports. 2023.04; 13 (1): 6747. ( PubMed , DOI )

  12. Maiko Inotsume, Tomoki Chiba, Takahide Matsushima, Ryota Kurimoto, Mitsuyo Nakajima, Tomomi Kato, Kana Shishido, Lin Liu, Koichi Kawakami, Hiroshi Asahara: One-step generation of mice with gene editing by Tol2 transposon-dependent gRNA delivery. FEBS Lett. 2023.03; ( PubMed , DOI )

  13. Yamano K, Sawada M, Kikuchi R, Nagataki K, Kojima W, Sugihara A, Fujino T, Tanaka K, Hayashi G, Murakami H, Matsuda N. : Optineurin provides a mitophagy contact site for TBK1 activation bioRxiv. 2023.02;

  14. Hayashida R, Kikuchi R, Imai K, Kojima W, Yamada T, Iijima M, Sesaki H, Tanaka K, Matsuda N, Yamano K: Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid-liquid phase separation-based method. The Journal of biological chemistry. 2023.02; 299 (2): 102822. ( PubMed , DOI )

  15. Jin X, Tanaka H, Jin M, Fujita K, Homma H, Inotsume M, Yong H, Umeda K, Kodera N, Ando T, Okazawa H: PQBP5/NOL10 maintains and anchors the nucleolus under physiological and osmotic stress conditions. Nat Commun. 2023.01; 14 (1): 9. ( PubMed , DOI )

  16. Hiroto Yamamoto, Yutaro Uchida, Ryota Kurimoto, Tomoki Chiba, Takahide Matsushima, Yoshiaki Ito, Maiko Inotsume, Kohei Miyata, Kenta Watanabe, Masaki Inada, Naoki Goshima, Tokujiro Uchida, Hiroshi Asahara: RNA-binding protein LIN28A upregulates transcription factor HIF1α by posttranscriptional regulation via direct binding to UGAU motifs. J Biol Chem. 2023.01; 299 (1): 102791. ( PubMed , DOI )

  1. Guangwei Cui, Akihiro Shimba, Jianshi Jin, Taisaku Ogawa, Yukiko Muramoto, Hitoshi Miyachi, Shinya Abe, Takuma Asahi, Shizue Tani-Ichi, Johannes M Dijkstra, Yayoi Iwamoto, Kirill Kryukov, Yuanbo Zhu, Daichi Takami, Takahiro Hara, Satsuki Kitano, Yan Xu, Hajime Morita, Moyu Zhang, Lynn Zreka, Keishi Miyata, Takashi Kanaya, Shinya Okumura, Takashi Ito, Etsuro Hatano, Yoshimasa Takahashi, Hiroshi Watarai, Yuichi Oike, Tadashi Imanishi, Hiroshi Ohno, Toshiaki Ohteki, Nagahiro Minato, Masato Kubo, Georg A Holländer, Hideki Ueno, Takeshi Noda, Katsuyuki Shiroguchi, Koichi Ikuta: A circulating subset of iNKT cells mediates antitumor and antiviral immunity. Sci Immunol. 2022.10; 7 (76): eabj8760. ( PubMed , DOI )

  2. Loems Ziegler-Heitbrock, Toshiaki Ohteki, Florent Ginhoux, Ken Shortman, Hergen Spits: Reclassifying plasmacytoid dendritic cells as innate lymphocytes. Nat Rev Immunol. 2022.10; 23 (1): 1-2. ( PubMed , DOI )

  3. Sonn I, Honda-Ozaki F, Yoshimatsu S, Morimoto S, Watanabe H, Okano H: Single transcription factor efficiently leads human induced pluripotent stem cells to functional microglia. Inflammation and regeneration. 2022.07; 42 (1): 20. ( PubMed , DOI )

  4. Tanaka H, Okazawa H: PQBP1: The Key to Intellectual Disability, Neurodegenerative Diseases, and Innate Immunity. Int J Mol Sci. 2022.06; 23 (11): 6227. ( PubMed , DOI )

  5. Sonn Iki, Honda-Ozaki Fumiko, Yoshimatsu Sho, Morimoto Satoru, Watanabe Hirotaka, Okano Hideyuki: 一つの転写因子が高い効率でヒト人工多能性幹細胞を機能性ミクログリアに誘導する(Single transcription factor efficiently leads human induced pluripotent stem cells to functional microglia) Inflammation and Regeneration. 2022.06; 42 1 of 20-20 of 20. ( 医中誌 )

  6. Yuta Fujii, Lin Liu, Lisa Yagasaki, Maiko Inotsume, Tomoki Chiba, Hiroshi Asahara: Cartilage Homeostasis and Osteoarthritis. Int J Mol Sci. 2022.06; 23 (11): ( PubMed , DOI )

  7. Shiwaku H, Katayama S, Kondo K, Nakano Y, Tanaka H, Yoshioka Y, Fujita K, Tamaki H, Takebayashi H, Terasaki O, Nagase Y, Nagase T, Kubota T, Ishikawa K, Okazawa H, Takahashi H: Autoantibodies against NCAM1 from patients with schizophrenia cause schizophrenia-related behavior and changes in synapses in mice. Cell Rep Med. 2022.04; 3 (4): 100597. ( PubMed , DOI )

  1. Adachi A, Honda T, Dainichi T, Egawa G, Yamamoto Y, Nomura T, Nakajima S, Otsuka A, Maekawa M, Mano N, Koyanagi N, Kawaguchi Y, Ohteki T, Nagasawa T, Ikuta K, Kitoh A, Kabashima K.: Prolonged high-intensity exercise induces fluctuating immune responses to herpes simplex virus infection via glucocorticoids. J Allergy Clin Immunol. 2021.12;

  2. Okazawa H, Tanaka H: Molecular Dissection and Therapeutic Application of SCA1 Pathologies Revealed by Comprehensive Approaches. Cerebellum as a CNS Hub. 2021.11; 479-486.

  3. Bruno Barros Queliconi, Waka Kojima, Mayumi Kimura, Kenichiro Imai, Chisato Udagawa, Chie Motono, Takatsugu Hirokawa, Shinya Tashiro, Jose M M Caaveiro, Kouhei Tsumoto, Koji Yamano, Keiji Tanaka, Noriyuki Matsuda: Unfolding is the driving force for mitochondrial import and degradation of the Parkinson's disease-related protein DJ-1. J Cell Sci. 2021.11; 134 (22): jcs258653. ( PubMed , DOI )

  4. Ohteki T, Kawamura S, Onai N.: Commitment to dendritic cells and monocytes. Int Immunol.. 2021.11;

  5. Jin M, Shiwaku H, Tanaka H, Obita T, Ohuchi S, Yoshioka Y, Jin X, Kondo K, Fujita K, Homma H, Nakajima K, Mizuguchi M, Okazawa H: Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation. Nat Commun. 2021.11; 12 (1): 6565. ( PubMed , DOI )

  6. Yamano K, Kojima W: Molecular functions of autophagy adaptors upon ubiquitin-driven mitophagy. Biochimica et biophysica acta. General subjects. 2021.10; 1865 (10): 129972. ( PubMed , DOI )

  7. Tanaka H, Kondo K, Fujita K, Homma H, Tagawa K, Jin X, Jin M, Yoshioka Y, Takayama S, Masuda H, Tokuyama R, Nakazaki Y, Saito T, Saido T, Murayama S, Ikura T, Ito N, Yamamori Y, Tomii K, Bianchi ME, Okazawa H: HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer's disease pathology. Commun Biol. 2021.10; 4 (1): 1175. ( PubMed , DOI )

  8. Waka Kojima, Koji Yamano, Hidetaka Kosako, Kenichiro Imai, Reika Kikuchi, Keiji Tanaka, Noriyuki Matsuda: Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy. Autophagy. 2021.08; 17 (8): 2011-2036. ( PubMed , DOI )

  9. Kondo K, Ikura T, Tanaka H, Fujita K, Takayama S, Yoshioka Y, Tagawa K, Homma H, Liu S, Kawasaki R, Huang Y, Ito N, Tate SI, Okazawa H: Hepta-Histidine Inhibits Tau Aggregation. ACS Chem Neurosci. 2021.08; 12 (16): 3015-3027. ( PubMed , DOI )

  10. Jin M, Jin X, Homma H, Fujita K, Tanaka H, Murayama S, Akatsu H, Tagawa K, Okazawa H: Prediction and verification of the AD-FTLD common pathomechanism based on dynamic molecular network analysis. Commun Biol. 2021.08; 4 (1): 961. ( PubMed , DOI )

  11. Yukiko Yoshida, Makoto Asahina, Arisa Murakami, Junko Kawawaki, Meari Yoshida, Reiko Fujinawa, Kazuhiro Iwai, Ryuichi Tozawa, Noriyuki Matsuda, Keiji Tanaka, Tadashi Suzuki: Loss of peptide N-glycanase causes proteasome dysfunction mediated by a sugar-recognizing ubiquitin ligase. Proc Natl Acad Sci U S A. 2021.07; 118 (27): e2102902118. ( PubMed , DOI )

  12. Taiki Baba, Susumu Tanimura, Ayane Yamaguchi, Koichiro Horikawa, Masashi Yokozeki, Saki Hachiya, Shun-Ichiro Iemura, Tohru Natsume, Noriyuki Matsuda, Kohsuke Takeda: Cleaved PGAM5 dephosphorylates nuclear serine/arginine-rich proteins during mitophagy. Biochim Biophys Acta Mol Cell Res. 2021.07; 1868 (7): 119045. ( PubMed , DOI )

  13. Yoshiaki Ito, Tokio Matsuzaki, Fumiaki Ayabe, Sho Mokuda, Ryota Kurimoto, Takahide Matsushima, Yusuke Tabata, Maiko Inotsume, Hiroki Tsutsumi, Lin Liu, Masahiro Shinohara, Yoko Tanaka, Ryo Nakamichi, Keiichiro Nishida, Martin K Lotz, Hiroshi Asahara: Both microRNA-455-5p and -3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis. Nat Commun. 2021.07; 12 (1): 4148. ( PubMed , DOI )

  14. Homma H, Tanaka H, Jin M, Jin X, Huang Y, Yoshioka Y, Bertens CJ, Tsumaki K, Kondo K, Shiwaku H, Tagawa K, Akatsu H, Atsuta N, Katsuno M, Furukawa K, Ishiki A, Waragai M, Ohtomo G, Iwata A, Yokota T, Inoue H, Arai H, Sobue G, Sone M, Fujita K, Okazawa H: DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis. Life Sci Alliance. 2021.06; 4 (7): e202101022. ( PubMed , DOI )

  15. Hitoshi Okazawa: Intracellular amyloid hypothesis for ultra-early phase pathology of Alzheimer's disease. Neuropathology. 2021.04; 41 (2): 93-98. ( PubMed , DOI )

  16. Kase, N; Terashima, M; Ohta, A; Niwa, A; Honda-Ozaki, F; Kawasaki, Y; Nakahata, T; Kanazawa, N; Saito, MK: Pluripotent stem cell-based screening identifiesCUDC-907 as an effective compound for restoring the in vitro phenotype ofNakajo-Nishimurasyndrome STEM CELLS TRANSLATIONAL MEDICINE. 2021.03; 10 (3): 455-464. ( PubMed , DOI )

  17. Saito M, Nakayama M, Fujita K, Uchida A, Yano H, Goto S, Okazawa H, Sone M: Role of the Drosophila YATA protein in the proper subcellular localization of COPI revealed by in vivo analysis. Genes Genet Syst. 2021.03; 95 (6): 303-314. ( PubMed , DOI )

  18. Chikuma S, Yamanaka S, Nakagawa S, Ueda MT, Hayabuchi H, Tokifuji Y, Kanayama M, Okamura T, Arase H, Yoshimura A: TRIM28 Expression on Dendritic Cells Prevents Excessive T Cell Priming by Silencing Endogenous Retrovirus. Journal of immunology (Baltimore, Md. : 1950). 2021.02; 206 (7): 1528-1539. ( PubMed , DOI )

  19. Izumi Y, Kanayama M, Shen Z, Kai M, Kawamura S, Akiyama M, Yamamoto M, Nagao T, Okada K, Kawamata N, Toyota S, Ohteki T: An Antibody-Drug Conjugate That Selectively Targets Human Monocyte Progenitors for Anti-Cancer Therapy. Frontiers in immunology. 2021.02; 12 618081. ( PubMed , DOI )

  20. Mashun Onishi, Koji Yamano, Miyuki Sato, Noriyuki Matsuda, Koji Okamoto: Molecular mechanisms and physiological functions of mitophagy. EMBO J. 2021.02; 40 (3): e104705. ( PubMed , DOI )

  21. Izumi Y, Kanayama M, Shen Z, Kai M, Kawamura S, Akiyama M, Yamamoto M, Nagao T, Okada K, Kawamata N, Toyota S, Ohteki T.: An Antibody-Drug Conjugate That Selectively Targets Human Monocyte Progenitors for Anti-Cancer Therapy. Front Immunol.. 2021.02; 12 618081..

  22. Daniel J Klionsky, etc.: Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 2021.02; 1-382. ( PubMed , DOI )

  1. Yamano K, Youle RJ: Two different axes CALCOCO2-RB1CC1 and OPTN-ATG9A initiate PRKN-mediated mitophagy. Autophagy. 2020.11; 16 (11): 2105-2107. ( PubMed , DOI )

  2. Tanaka Hikari, Kondo Kanoh, Chen Xigui, Homma Hidenori, Tagawa Kazuhiko, Saido Takaomi, Muramatsu Shin-ichi, Fujita Kyota, Okazawa Hitoshi: 超早期アルツハイマー病においてSRRM2リン酸化はシナプス病理を誘発する(Phosphorylation of SRRM2 leads to synaptic pathology at ultra-early phase of Alzheimer's disease) 臨床神経学. 2020.11; 60 (Suppl.): S345. ( 医中誌 )

  3. Matsuda N, Yamano K: Two sides of a coin: Physiological significance and molecular mechanisms for damage-induced mitochondrial localization of PINK1 and Parkin. Neuroscience research. 2020.10; 159 16-24. ( PubMed , DOI )

  4. Hiroto Yamamoto, Yutaro UchidaI, Tomoki Chiba, Ryota Kurimoto,Takahide Matsushima, Maiko Inotsume, Chihiro Ishikawa, Haiyan Li, Takashi Shiga, Masafumi Muratani, Tokujiro Uchida, Hiroshi Asahara: Transcriptome analysis of sevoflurane exposure effects at the different brain regions PLOS ONE. 2020.10;

  5. Kana Minamide, Taku Sato, Yusuke Nakanishi, Hiroshi Ohno, Tamotsu Kato, Jumpei Asano, Toshiaki Ohteki: IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon. Sci Rep. 2020.09; 10 (1): 14639. ( PubMed , DOI )

  6. Kanayama M, Izumi Y, Yamauchi Y, Kuroda S, Shin T, Ishikawa S, Sato T, Kajita M, Ohteki T.: CD86-based analysis enables observation of bona fide hematopoietic responses Blood.. 2020.09; 136 (10): 1144-1154.

  7. Koji Yamano, Reika Kikuchi, Waka Kojima, Ryota Hayashida, Fumika Koyano, Junko Kawawaki, Takuji Shoda, Yosuke Demizu, Mikihiko Naito, Keiji Tanaka, Noriyuki Matsuda: Critical role of mitochondrial ubiquitination and the OPTN ATG9A axis in mitophagy Journal of Cell Biology. 2020.09; 219 (9): ( PubMed , DOI )

  8. Yamano K, Kikuchi R, Kojima W, Hayashida R, Koyano F, Kawawaki J, Shoda T, Demizu Y, Naito M, Tanaka K, Matsuda N: Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy. The Journal of cell biology. 2020.09; 219 (9): ( PubMed , DOI )

  9. Sato T, Ishikawa S, Asano J, Yamamoto H, Fujii M, Sato T, Yamamoto K, Kitagaki K, Akashi T, Okamoto R, Ohteki T.: Regulated IFN signalling preserves the stemness of intestinal stem cells by restricting differentiation into secretory-cell lineages. Nat Cell Biol. . 2020.08; 22 (8): 919-926.

  10. Liang J, Zhang JJ, Huang HI, Kanayama M, Youssef N, Jin YJ, Reyes EY, Abram CL, Yang S, Lowell CA, Wang D, Shao L, Shinohara ML, Zhang JY, Hammer GE: The ubiquitin-modifying enzyme A20 terminates C-type lectin receptor signals and is a suppressor of host defense against systemic fungal infection. Infection and immunity. 2020.06; 88 (9): ( PubMed , DOI )

  11. Kanayama M, Izumi Y, Yamauchi Y, Kuroda S, Shin T, Ishikawa S, Sato T, Kajita M, Ohteki T: CD86-based analysis enables observation of bona fide hematopoietic responses. Blood. 2020.05; ( PubMed , DOI )

  12. Taku Sato, Miwako Sase, Shun Ishikawa, Mihoko Kajita, Jumpei Asano, Toshiro Sato, Yoshiyuki Mori, Toshiaki Ohteki: Characterization of radioresistant epithelial stem cell heterogeneity in the damaged mouse intestine. Sci Rep. 2020.05; 10 (1): 8308. ( PubMed , DOI )

  13. Yang SS, Ishida T, Fujita K, Nakai Y, Ono T, Okazawa H: PQBP1, an intellectual disability causative gene, affects bone development and growth. Biochem Biophys Res Commun. 2020.03; 523 (4): 894-899. ( PubMed , DOI )

  14. Yang SS, Ishida T, Fujita K, Nakai Y, Ono T, Okazawa H. : PQBP1, an intellectual disability causative gene, affects bone development and growth. Biochemical and Biophysical Research Communications.. 2020.03; 523 894-899. ( DOI )

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  4. Takayuki Yokoi, Kentarou Yokoi, Kazumasa Akiyama, Takashi Higuchi, Yohta Shimada, Hiroshi Kobayashi, Taku Sato, Toshiaki Ohteki, Makoto Otsu, Hiromitsu Nakauchi, Hiroyuki Ida, Toya Ohashi: Non-myeloablative preconditioning with ACK2 (anti-c-kit antibody) is efficient in bone marrow transplantation for murine models of mucopolysaccharidosis type II. Mol. Genet. Metab.. 2016.11; 119 (3): 232-238. ( PubMed , DOI )

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  1. 部位特異的光架橋によるリン酸化Parkinとリン酸化ユビキチンの相互作用マッピングから明らかになったParkinの活性化メカニズム 2015.12; 88回・38回 [1P0015]. ( 医中誌 )

  2. Tsutomu Endo, Koyu Ito, Junko Morimoto, Masashi Kanayama, Daichi Ota, Masahiro Ikesue, Shigeyuki Kon, Daisuke Takahashi, Tomohiro Onodera, Norimasa Iwasaki, Toshimitsu Uede: Syndecan 4 Regulation of the Development of Autoimmune Arthritis in Mice by Modulating B Cell Migration and Germinal Center Formation. Arthritis & rheumatology (Hoboken, N.J.). 2015.09; 67 (9): 2512-2522. ( PubMed , DOI )

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  5. Hiroshi Kobayashi, Chiharu I Kobayashi, Ayako Nakamura-Ishizu, Daiki Karigane, Hiroshi Haeno, Kimiyo N Yamamoto, Taku Sato, Toshiaki Ohteki, Yoshihiro Hayakawa, Glen N Barber, Mineo Kurokawa, Toshio Suda, Keiyo Takubo: Bacterial c-di-GMP affects hematopoietic stem/progenitors and their niches through STING. Cell Rep. 2015.04; 11 (1): 71-84. ( PubMed , DOI )

  6. Shiwaku H, Okazawa H: Impaired DNA damage repair as a common feature of neurodegenerative diseases and psychiatric disorders. Current Molecular Medicine. 2015.02; 15 (2): 119-128. ( PubMed , DOI )

  7. Y Nakanishi, T Sato, T Ohteki: Commensal Gram-positive bacteria initiates colitis by inducing monocyte/macrophage mobilization. Mucosal Immunol. 2015.01; 8 (1): 152-160. ( PubMed , DOI )

  8. Masashi Kanayama, Makoto Inoue, Keiko Danzaki, Gianna Hammer, You-Wen He, Mari L Shinohara: Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity. Nature Communications. 2015.01; 6 5779. ( PubMed , DOI )

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  10. Tagawa K, Homma H, Saito A, Fujita K, Chen X, Imoto S, Oka T, Ito H, Motoki K, Yoshida C, Hatsuta H, Murayama S, Iwatsubo T, Miyano S, Okazawa H. : Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain. Human Molecular Genetics.. 2015.01; 24 540-558. ( DOI )

  1. Shiraishi R, Tamura T, Sone M, Okazawa H: Systematic analysis of fly models with multiple drivers reveals different effects of ataxin-1 and huntingtin in neuron subtype-specific expression. PLoS ONE. 2014.12; 9 (12): e116567. ( PubMed , DOI )

  2. Nabeshima Y, Mizuguchi M, Kajiyama A, Okazawa H: Segmental isotope-labeling of the intrinsically disordered protein PQBP1. FEBS Letters. 2014.12; 588 (24): 4583-4589. ( PubMed , DOI )

  3. Daichi Ota, Masashi Kanayama, Yutaka Matsui, Koyu Ito, Naoyoshi Maeda, Goro Kutomi, Koichi Hirata, Toshihiko Torigoe, Noriyuki Sato, Akinori Takaoka, Ann F Chambers, Junko Morimoto, Toshimitsu Uede: Tumor-α9β1 integrin-mediated signaling induces breast cancer growth and lymphatic metastasis via the recruitment of cancer-associated fibroblasts. J. Mol. Med.. 2014.12; 92 (12): 1271-1281. ( PubMed , DOI )

  4. Shigeyuki Kon, Yosuke Nakayama, Naoki Matsumoto, Koyu Ito, Masashi Kanayama, Chiemi Kimura, Hitomi Kouro, Dai Ashitomi, Tadashi Matsuda, Toshimitsu Uede: A novel cryptic binding motif, LRSKSRSFQVSDEQY, in the C-terminal fragment of MMP-3/7-cleaved osteopontin as a novel ligand for α9β1 integrin is involved in the anti-type II collagen antibody-induced arthritis. PLoS ONE. 2014.12; 9 (12): e116210. ( PubMed , DOI )

  5. Tagawa, K., Homma, H., Saito, A., Fujita, K., Chen, X., Imoto, S., Oka, T., Ito, H., Motoki, K., Yoshida, C., Hatsuta, H., Murayama, S., Iwatsubo, T., Miyano, S., Okazawa, H.: Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain. Hum Mol Genet. 2014.09; ( PubMed , DOI )

  6. Ito, H., Shiwaku, H., Yoshida, C., Homma, H., Luo, H., Chen, X., Fujita, K., Musante, L., Fischer, U., Frints, S G M., Romano, C., Ikeuchi, Y., Shimamura, T., Imoto, S., Miyano, S., Muramatsu, S-I., Kawauchi, T., Hoshino, M., Sudol, M., Arumughan, A., Wanker, E E., Rich, T., Schwartz, C., Matsuzaki, F., Bonni, A., Kalscheuer, V M., Okazawa, H.: In utero gene therapy rescues microcephaly caused by Pqbp1-hypofunction in neural stem progenitor cells. Mol Psychiatry. 2014.07; 20 (4): 459-71. ( PubMed , DOI )

  7. Nobuyuki Onai, Toshiaki Ohteki: Bipotent or Oligopotent? A Macrophage and DC Progenitor Revisited. Immunity. 2014.07; 41 (1): 5-7. ( PubMed , DOI )

  8. A Yokota-Nakatsuma, H Takeuchi, Y Ohoka, C Kato, S-Y Song, T Hoshino, H Yagita, T Ohteki, M Iwata: Retinoic acid prevents mesenteric lymph node dendritic cells from inducing IL-13-producing inflammatory Th2 cells. Mucosal Immunol. 2014.07; 7 (4): 786-801. ( PubMed , DOI )

  9. Mizuguchi M, Obita T, Serita T, Kojima R, Nabeshima Y, Okazawa H: Mutations in the PQBP1 gene prevent its interaction with the spliceosomal protein U5-15 kD. Nat Commun. 2014.04; 5 3822. ( PubMed , DOI )

  10. Barclay SS, Tamura T, Ito H, Fujita K, Tagawa K, Shimamura T, Katsuta A, Shiwaku H, Sone M, Imoto S, Miyano S, Okazawa H: Systems biology analysis of Drosophila in vivo screen data elucidates core networks for DNA damage repair in SCA1. Hum Mol Genet. 2014.03; 23 (5): 1345-1364. ( PubMed , DOI )

  11. Tsuyoshi Asano, Norimasa Iwasaki, Shigeyuki Kon, Masashi Kanayama, Junko Morimoto, Akio Minami, Toshimitsu Uede: α9β1 integrin acts as a critical intrinsic regulator of human rheumatoid arthritis. Rheumatology (Oxford). 2014.03; 53 (3): 415-424. ( PubMed , DOI )

  1. Ikeuchi Y, de la Torre-Ubieta L, Matsuda T, Steen H, Okazawa H, Bonni A: The XLID protein PQBP1 and the GTPase Dynamin 2 define a signaling link that orchestrates ciliary morphogenesis in postmitotic neurons. Cell Rep. 2013.09; 4 (5): 879-889. ( PubMed , DOI )

  2. Takayuki Sato, Toshio Kitawaki, Haruyuki Fujita, Makoto Iwata, Tomonori Iyoda, Kayo Inaba, Toshiaki Ohteki, Suguru Hasegawa, Kenji Kawada, Yoshiharu Sakai, Hiroki Ikeuchi, Hiroshi Nakase, Akira Niwa, Akifumi Takaori-Kondo, Norimitsu Kadowaki: Human CD1c⁺ myeloid dendritic cells acquire a high level of retinoic acid-producing capacity in response to vitamin D₃. J Immunol. 2013.09; 191 (6): 3152-3160. ( PubMed , DOI )

  3. Hideaki Ohyagi, Nobuyuki Onai, Taku Sato, Satoshi Yotsumoto, Jiajia Liu, Hisaya Akiba, Hideo Yagita, Koji Atarashi, Kenya Honda, Axel Roers, Werner Müller, Kazutaka Kurabayashi, Mayuka Hosoi-Amaike, Naoto Takahashi, Makoto Hirokawa, Kouji Matsushima, Kenichi Sawada, Toshiaki Ohteki: Monocyte-derived dendritic cells perform hemophagocytosis to fine-tune excessive immune responses. Immunity. 2013.09; 39 (3): 584-598. ( PubMed , DOI )

  4. Shiwaku H, Yagishita S, Eishi Y, Okazawa H: Bergmann glia are reduced in spinocerebellar ataxia type 1. Neuroreport. 2013.08; 24 (11): 620-625. ( PubMed , DOI )

  5. Li C, Ito H, Fujita K, Shiwaku H, Qi Y, Tagawa K, Tamura T, Okazawa H: Sox2 transcriptionally regulates PQBP1, an intellectual disability-microcephaly causative gene, in neural stem progenitor cells. PLoS ONE. 2013.07; 8 (7): e68627. ( PubMed , DOI )

  6. Atsushi Hayashi, Toshiro Sato, Nobuhiko Kamada, Yohei Mikami, Katsuyoshi Matsuoka, Tadakazu Hisamatsu, Toshifumi Hibi, Axel Roers, Hideo Yagita, Toshiaki Ohteki, Akihiko Yoshimura, Takanori Kanai: A single strain of Clostridium butyricum induces intestinal IL-10-producing macrophages to suppress acute experimental colitis in mice. Cell Host Microbe. 2013.06; 13 (6): 711-722. ( PubMed , DOI )

  7. Nobuyuki Onai, Kazutaka Kurabayashi, Mayuka Hosoi-Amaike, Noriko Toyama-Sorimachi, Kouji Matsushima, Kayo Inaba, Toshiaki Ohteki: A clonogenic progenitor with prominent plasmacytoid dendritic cell developmental potential. Immunity. 2013.05; 38 (5): 943-957. ( PubMed , DOI )

  8. Fujita K, Nakamura Y, Oka T, Ito H, Tamura T, Tagawa K, Sasabe T, Katsuta A, Motoki K, Shiwaku H, Sone M, Yoshida C, Katsuno M, Eishi Y, Murata M, Taylor JP, Wanker EE, Kono K, Tashiro S, Sobue G, La Spada AR, Okazawa H: A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases. Nat Commun. 2013.05; 4 1816. ( PubMed , DOI )

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  10. Tamura T, Sone M, Nakamura Y, Shimamura T, Imoto S, Miyano S, Okazawa H: A restricted level of PQBP1 is needed for the best longevity of Drosophila. Neurobiol Aging. 2013.01; 34 (1): 356.e11-356.e20. ( PubMed , DOI )

  11. Akihiko Ichikawa, Keiji Kuba, Masayuki Morita, Shinsuke Chida, Hiroyuki Tezuka, Hiromitsu Hara, Takehiko Sasaki, Toshiaki Ohteki, V Marco Ranieri, Claudia C dos Santos, Yoshihiro Kawaoka, Shizuo Akira, Andrew D Luster, Bao Lu, Josef M Penninger, Stefan Uhlig, Arthur S Slutsky, Yumiko Imai: CXCL10-CXCR3 enhances the development of neutrophil-mediated fulminant lung injury of viral and nonviral origin. Am J Respir Crit Care Med. 2013.01; 187 (1): 65-77. ( PubMed , DOI )

  1. Martin Rees, Christian Gorba, Cesira de Chiara, Tam T T Bui, Mitla Garcia-Maya, Alex F Drake, Hitoshi Okazawa, Annalisa Pastore, Dmitri Svergun, Yu Wai Chen: Solution model of the intrinsically disordered polyglutamine tract-binding protein-1. Biophys J. 2012.04; 102 (7): 1608-1616. ( PubMed , DOI )

  2. Jiajia Liu, Yong-Mei Guo, Makoto Hirokawa, Keiko Iwamoto, Kumi Ubukawa, Yoshihiro Michishita, Naohito Fujishima, Hiroyuki Tagawa, Naoto Takahashi, Weiguo Xiao, Junsuke Yamashita, Toshiaki Ohteki, Kenichi Sawada: A synthetic double-stranded RNA, poly I:C, induces a rapid apoptosis of human CD34(+) cells. Exp Hematol. 2012.04; 40 (4): 330-341. ( PubMed , DOI )

  3. Nakamura Y, Tagawa K, Oka T, Sasabe T, Ito H, Shiwaku H, La Spada AR, Okazawa H: Ataxin-7 associates with microtubules and stabilizes the cytoskeletal network. Hum Mol Genet. 2012.03; 21 (5): 1099-1110. ( PubMed , DOI )

  4. Keiko Danzaki, Yutaka Matsui, Masahiro Ikesue, Daichi Ohta, Koyu Ito, Masashi Kanayama, Daisuke Kurotaki, Junko Morimoto, Yoichiro Iwakura, Hideo Yagita, Hiroyuki Tsutsui, Toshimitsu Uede: Interleukin-17A deficiency accelerates unstable atherosclerotic plaque formation in apolipoprotein E-deficient mice. Arterioscler. Thromb. Vasc. Biol.. 2012.02; 32 (2): 273-280. ( PubMed , DOI )

  5. Yukinori Tsukuda, Norimasa Iwasaki, Naoki Seito, Masashi Kanayama, Naoki Fujitani, Yasuro Shinohara, Yasuhiko Kasahara, Tomohiro Onodera, Koji Suzuki, Tsuyoshi Asano, Akio Minami, Tadashi Yamashita: Ganglioside GM3 has an essential role in the pathogenesis and progression of rheumatoid arthritis. PLoS ONE. 2012.01; 7 (6): e40136. ( PubMed , DOI )

  1. Masashi Kanayama, Junko Morimoto, Yutaka Matsui, Masahiro Ikesue, Keiko Danzaki, Daisuke Kurotaki, Koyu Ito, Toshimichi Yoshida, Toshimitsu Uede: α9β1 integrin-mediated signaling serves as an intrinsic regulator of pathogenic Th17 cell generation. J. Immunol.. 2011.12; 187 (11): 5851-5864. ( PubMed , DOI )

  2. Tamura T, Sone M, Iwatsubo T, Tagawa K, Wanker EE, Okazawa H: Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease. PLoS ONE. 2011.11; 6 (11): e27408. ( PubMed , DOI )

  3. Hirosato Mashima, Taku Sato, Yasuo Horie, Yuko Nakagawa, Itaru Kojima, Toshiaki Ohteki, Hirohide Ohnishi: Interferon regulatory factor-2 regulates exocytosis mechanisms mediated by SNAREs in pancreatic acinar cells. Gastroenterology. 2011.09; 141 (3): 1102-1113.e1. ( PubMed , DOI )

  4. Oka T, Tagawa K, Ito H, Okazawa H: Dynamic changes of the phosphoproteome in postmortem mouse brains. PLoS ONE. 2011.06; 6 (6): e21405. ( PubMed , DOI )

  5. 樗木俊聡: 腸管粘膜における樹状細胞の役割(The Role of dendritic cells in the intestinal mucosa) 日本耳鼻咽喉科学会会報 114. 2011.06; 107-113.

  6. Hiroyuki Tezuka, Yukiko Abe, Jumpei Asano, Taku Sato, Jiajia Liu, Makoto Iwata, Toshiaki Ohteki: Prominent role for plasmacytoid dendritic cells in mucosal T cell-independent IgA induction. Immunity. 2011.02; 34 (2): 247-257. ( PubMed , DOI )

  7. Daisuke Kurotaki, Shigeyuki Kon, Kyeonghwa Bae, Koyu Ito, Yutaka Matsui, Yosuke Nakayama, Masashi Kanayama, Chiemi Kimura, Yoshinori Narita, Takashi Nishimura, Kazuya Iwabuchi, Matthias Mack, Nico van Rooijen, Shimon Sakaguchi, Toshimitsu Uede, Junko Morimoto: CSF-1-dependent red pulp macrophages regulate CD4 T cell responses. J. Immunol.. 2011.02; 186 (4): 2229-2237. ( PubMed , DOI )

  1. Yoshitake Kanazawa, Yasuyuki Saito, Yana Supriatna, Hiroyuki Tezuka, Takenori Kotani, Yoji Murata, Hideki Okazawa, Hiroshi Ohnishi, Yoshitaka Kinouchi, Yoshihisa Nojima, Toshiaki Ohteki, Tooru Shimosegawa, Takashi Matozaki: Role of SIRPα in regulation of mucosal immunity in the intestine. Genes Cells. 2010.12; 15 (12): 1189-1200. ( PubMed , DOI )

  2. Aoki Y, Nakamura A, Yokota T, Saito T, Okazawa H, Nagata T, Takeda SI: In-frame dystrophin following exon 51-skipping improves muscle pathology and function in the exon 52-deficient mdx mouse. Mol Ther. 2010.11; 18 (11): 1995-2005. ( PubMed , DOI )

  3. Hiroyuki Tezuka, Toshiaki Ohteki: A gas governing mucosal immunity. Vaccine. 2010.11; 28 (50): 8039-8040. ( PubMed , DOI )

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  5. Konno M, Hamazaki TS, Fukuda S, Tokuhara M, Uchiyama H, Okazawa H, Okochi H, Asashima M: Efficiently differentiating vascular endothelial cells from adipose tissue-derived mesenchymal stem cells in serum-free culture. Biochem Biophys Res Commun. 2010.10; 400 (4): 461-465. ( PubMed , DOI )

  6. Honda S, Hayashi S, Imoto I, Toyama J, Okazawa H, Nakagawa E, Goto Y, Inazawa J: Copy-number variations on the X chromosome in Japanese patients with mental retardation detected by array-based comparative genomic hybridization analysis. J Hum Genet. 2010.09; 55 (9): 590-599. ( PubMed , DOI )

  7. Shiwaku H, Yoshimura N, Tamura T, Sone M, Ogishima S, Watase K, Tagawa K, Okazawa H: Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity. EMBO J. 2010.07; 29 (14): 2446-2460. ( PubMed , DOI )

  8. Takahashi M, Mizuguchi M, Shinoda H, Aizawa T, Demura M, Okazawa H, Kawano K: Polyglutamine tract-binding protein-1 binds to U5-15kD via a continuous 23-residue segment of the C-terminal domain. Biochim Biophys Acta. 2010.07; 1804 (7): 1500-1507. ( PubMed , DOI )

  9. Yong-Mei Guo, Keiko Ishii, Makoto Hirokawa, Hiroyuki Tagawa, Hideaki Ohyagi, Yoshihiro Michishita, Kumi Ubukawa, Junsuke Yamashita, Toshiaki Ohteki, Nobuyuki Onai, Kazuyoshi Kawakami, Weiguo Xiao, Kenichi Sawada: CpG-ODN 2006 and human parvovirus B19 genome consensus sequences selectively inhibit growth and development of erythroid progenitor cells. Blood. 2010.06; 115 (22): 4569-4579. ( PubMed , DOI )

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  11. Hiroyuki Tezuka, Toshiaki Ohteki: Regulation of intestinal homeostasis by dendritic cells. Immunol Rev. 2010.03; 234 (1): 247-258. ( PubMed , DOI )

  12. Jumpei Asano, Hiroyuki Tada, Nobuyuki Onai, Taku Sato, Yasuo Horie, Yukari Fujimoto, Koichi Fukase, Akira Suzuki, Tak W Mak, Toshiaki Ohteki: Nucleotide oligomerization binding domain-like receptor signaling enhances dendritic cell-mediated cross-priming in vivo. J Immunol. 2010.01; 184 (2): 736-745. ( PubMed , DOI )

  1. Ito H, Yoshimura N, Kurosawa M, Ishii S, Nukina N, Okazawa H: Knock-down of PQBP1 impairs anxiety-related cognition in mouse. Hum Mol Genet. 2009.11; 18 (22): 4239-4254. ( PubMed , DOI )

  2. Takayuki Tomita, Takanori Kanai, Teruji Totsuka, Yasuhiro Nemoto, Ryuichi Okamoto, Kiichiro Tsuchiya, Naoya Sakamoto, Toshiaki Ohteki, Toshifumi Hibi, Mamoru Watanabe: IL-7 is essential for lymphopenia-driven turnover of colitogenic CD4(+) memory T cells in chronic colitis. Eur J Immunol. 2009.10; 39 (10): 2737-2747. ( PubMed , DOI )

  3. Chin JH, Shiwaku H, Goda O, Komuro A, Okazawa H: Neural stem cells express Oct-3/4. Biochem Biophys Res Commun. 2009.10; 388 (2): 247-251. ( PubMed , DOI )

  4. Takahashi M, Mizuguchi M, Shinoda H, Tomoyasu AT, Demura M, Okazawa H, Kawano K: Polyglutamine tract binding protein-1 is an intrinsically unstructured protein Biochim. Biophys. Acta. 2009.06; 1794 (6): 936-943. ( PubMed , DOI )

  5. Masashi Kanayama, Daisuke Kurotaki, Junko Morimoto, Tsuyoshi Asano, Yutaka Matsui, Yosuke Nakayama, Yoshinari Saito, Koyu Ito, Chiemi Kimura, Norimasa Iwasaki, Koji Suzuki, Tanenobu Harada, Hong Mei Li, Jun Uehara, Tadaaki Miyazaki, Akio Minami, Shigeyuki Kon, Toshimitsu Uede: Alpha9 integrin and its ligands constitute critical joint microenvironments for development of autoimmune arthritis. J. Immunol.. 2009.06; 182 (12): 8015-8025. ( PubMed , DOI )

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  7. Jun Yamada, Junji Hamuro, Atsuki Fukushima, Toshiaki Ohteki, Kazuto Terai, Yoichiro Iwakura, Hideo Yagita, Shigeru Kinoshita: MHC-matched corneal allograft rejection in an IFN-gamma/IL-17-independent manner in C57BL/6 mice. Invest Ophthalmol Vis Sci. 2009.05; 50 (5): 2139-2146. ( PubMed , DOI )

  8. Morimoto N, Nagai M, Miyazaki K, Kurata T, Takehisa Y, Ikeda Y, Kamiya T, Okazawa H, Abe K: Progressive decrease in the level of YAPdeltaCs, pro-survival isoforms of YAP, in the spinal cord of transgenic mouse carrying a mutant SOD1 gene J Neurosci Res. 2009.03; 87 (4): 928-936. ( PubMed )

  9. Sone M, Uchida A, Komatsu A, Suzuki E, Ibuki I, Asada M, Shiwaku H, Tamura T, Hoshino M, Okazawa H, Nabeshima Y: Loss of yata, a novel gene regulating the subcellular localization of APPL, induces deterioration of neural tissues and lifespan shortening. PLoS ONE. 2009.02; 4 (2): e4466. ( PubMed , DOI )

  10. Koyu Ito, Shigeyuki Kon, Yosuke Nakayama, Daisuke Kurotaki, Yoshinari Saito, Masashi Kanayama, Chiemi Kimura, Hongyan Diao, Junko Morimoto, Yutaka Matsui, Toshimitsu Uede: The differential amino acid requirement within osteopontin in alpha4 and alpha9 integrin-mediated cell binding and migration. Matrix Biol.. 2009.01; 28 (1): 11-19. ( PubMed , DOI )

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  1. Enokido Y, Yoshitake A, Ito H, Okazawa H: Age-dependent change of HMGB1 and DNA double-strand break accumulation in mouse brain Biochem Biophys Res Commun. 2008.11; 376 (1): 128-133. ( PubMed , DOI )

  2. Fumi Miyagawa, Yutaka Tagaya, Brian S Kim, Hiral J Patel, Kazuto Ishida, Toshiaki Ohteki, Thomas A Waldmann, Stephen I Katz: IL-15 serves as a costimulator in determining the activity of autoreactive CD8 T cells in an experimental mouse model of graft-versus-host-like disease. J Immunol. 2008.07; 181 (2): 1109-1119. ( PubMed )

  3. Inagaki R, Tagawa K, Qi ML, Enokido Y, Ito H, Tamura T, Shimizu S, Oyanagi K, Arai N, Kanazawa I, Wanker EE, Okazawa H: Omi / HtrA2 is relevant to the selective vulnerability of striatal neurons in Huntington's disease. Eur. J. Neurosci. 2008.07; 28 (1): 30-40. ( PubMed , DOI )

  4. Shoko Kuroda, Miki Nishio, Takehiko Sasaki, Yasuo Horie, Koichi Kawahara, Masato Sasaki, Miyuki Natsui, Takashi Matozaki, Hiroyuki Tezuka, Toshiaki Ohteki, Irmgard Förster, Tak W Mak, Toru Nakano, Akira Suzuki: Effective clearance of intracellular Leishmania major in vivo requires Pten in macrophages. Eur J Immunol. 2008.05; 38 (5): 1331-1340. ( PubMed , DOI )

  5. Magali Terme, Nathalie Chaput, Behazine Combadiere, Averil Ma, Toshiaki Ohteki, Laurence Zitvogel: Regulatory T cells control dendritic cell/NK cell cross-talk in lymph nodes at the steady state by inhibiting CD4+ self-reactive T cells. J Immunol. 2008.04; 180 (7): 4679-4686. ( PubMed )

  1. Yoshinari Saito, Shigeyuki Kon, Yukio Fujiwara, Yosuke Nakayama, Daisuke Kurotaki, Naoki Fukuda, Chiemi Kimura, Masashi Kanayama, Koyu Ito, Hongyan Diao, Yutaka Matsui, Yasuo Komatsu, Eiko Ohtsuka, Toshimitsu Uede: Osteopontin small interfering RNA protects mice from fulminant hepatitis. Hum. Gene Ther.. 2007.12; 18 (12): 1205-1214. ( PubMed , DOI )

  2. Nobuyuki Onai, Aya Obata-Onai, Michael A Schmid, Toshiaki Ohteki, David Jarrossay, Markus G Manz: Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow. Nat Immunol. 2007.11; 8 (11): 1207-1216. ( PubMed , DOI )

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  5. Hiroyuki Kishimoto, Toshiaki Ohteki, Nobuyuki Yajima, Koichi Kawahara, Miyuki Natsui, Satoru Kawarasaki, Koichi Hamada, Yasuo Horie, Yoshiaki Kubo, Seiji Arase, Masaru Taniguchi, Bart Vanhaesebroeck, Tak Wah Mak, Toru Nakano, Shigeo Koyasu, Takehiko Sasaki, Akira Suzuki: The Pten/PI3K pathway governs the homeostasis of Valpha14iNKT cells. Blood. 2007.04; 109 (8): 3316-3324. ( PubMed , DOI )

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  1. Toshiaki Ohteki, Hiroyuki Tada, Kazuto Ishida, Taku Sato, Chikako Maki, Taketo Yamada, Junji Hamuro, Shigeo Koyasu: Essential roles of DC-derived IL-15 as a mediator of inflammatory responses in vivo. J Exp Med. 2006.10; 203 (10): 2329-2338. ( PubMed , DOI )

  2. Marubuchi S, Okuda T, Tagawa K, Enokido Y, Horiuchi D, Shimokawa R, Tamura T, Qi ML, Eishi Y, Watabe K, Shibata M, Nakagawa M, Okazawa H: Hepatoma-derived growth factor, a new trophic factor for motor neurons, is up-regulated in the spinal cord of PQBP-1 transgenic mice before onset of degeneration. J Neurochem. 2006.10; 99 (1): 70-83. ( PubMed , DOI )

  3. Seiichi Kuwajima, Taku Sato, Kazuto Ishida, Hiroyuki Tada, Hiroyuki Tezuka, Toshiaki Ohteki: Interleukin 15-dependent crosstalk between conventional and plasmacytoid dendritic cells is essential for CpG-induced immune activation. Nat Immunol. 2006.07; 7 (7): 740-746. ( PubMed , DOI )

  4. Noriko Kitanaka, Yuji Owada, Ryuhei Okuyama, Hiroyuki Sakagami, Mohammad Reza Nourani, Setsuya Aiba, Hiroshi Furukawa, Makoto Watanabe, Masao Ono, Toshiaki Ohteki, Hisatake Kondo: Epidermal-type fatty acid binding protein as a negative regulator of IL-12 production in dendritic cells. Biochem Biophys Res Commun. 2006.06; 345 (1): 459-466. ( PubMed , DOI )

  5. Yoshimura N, Horiuchi D, Shibata M, Saitoe M, Qi ML, Okazawa H: Expression of human PQBP-1 in Drosophila impairs long-term memory and induces abnormal courtship. FEBS Lett. 2006.04; 580 (9): 2335-2340. ( PubMed , DOI )

  6. Hoshino M, Qi ML, Yoshimura N, Miyashita T, Tagawa K, Wada Y, Enokido Y, Marubuchi S, Harjes P, Arai N, Oyanagi K, Blandino G, Sudol M, Rich T, Kanazawa I, Wanker EE, Saitoe M, Okazawa H: Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73. J Cell Biol. 2006.02; 172 (4): 589-604. ( PubMed , DOI )

  1. Hiroyuki Tada, Setsuya Aiba, Ken-Ichiro Shibata, Toshiaki Ohteki, Haruhiko Takada: Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells. Infect Immun. 2005.12; 73 (12): 7967-7976. ( PubMed , DOI )

  2. Enokido Y, Suzuki E, Iwasawa K, Namekata K, Okazawa H, Kimura H: Cystathionine beta-synthase, a key enzyme for homocysteine metabolism, is preferentially expressed in the radial glia/astrocyte lineage of developing mouse CNS FASEB J. 2005.11; 19 (13): 1854-1856. ( PubMed , DOI )

  3. Marubuchi S, Wada Y, Okuda T, Hara Y, Qi ML, Hoshino M, Nakagawa M, Kanazawa I, Okazawa H: PQBP -1 dysfunction induces cell death of neurons through mitochondrial stress. J Neurochem. 2005.11; 95 (3): 858-870. ( PubMed , DOI )

  4. Qi Y, Hoshino M, Wada Y, Marubuchi S, Yoshimura N, Kanazawa I, Shinomiya K, Okazawa H: PQBP-1 is expressed predominantly in the central nervous system during development. Eur J Neurosci. 2005.09; 22 (6): 1277-1286. ( PubMed , DOI )

  1. Okuda T, Tagawa K, Qi ML, Hoshio M, Ueda H, Kawano H, Kanazawa I, Muramatsu M, Okazawa H: Oct-3/4 repression accelerates differentiation of neural progenitor cells in vitro and in vivo. Brain Res Mol Brain Res. 2004.12; 132 (1): 18-30. ( PubMed , DOI )

  2. Tagawa K, Hoshino M, Okuda T, Ueda H, Hayashi H, Engemann S, Okado H, Ichikawa M, Wanker EE, Okazawa H: Distinct aggregation and cell death patterns among different types of primary neurons induced by mutant huntingtin protein. J Neurochem. 2004.05; 89 (4): 974-987. ( PubMed , DOI )

  3. Hoshino M, Tagawa K, Okuda T, Ueda H, Okazawa H : General transcriptional repression by polyglutamine disease proteins is not directly linked to the presence of inclusion bodies Biochem. Biophys. Res. Commun. 2004.01; 313 (1): 110-116. ( PubMed , DOI )

  1. Hoshino M, Tagawa K, Okuda T, Murata M, Oyanagi K, Arai N, Mizutani T, Kanazawa I, Wanker EE, Okazawa H : Histone deacetylase activity is retained in primary neurons expressing mutant huntingtin protein J. Neurochem. 2003.10; 87 (1): 257-267. ( PubMed , DOI )

  2. Busch A, Engemann S, Lurz R, Okazawa H, Lehrach H, Wanker EE: Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease. J Biol Chem. 2003.10; 278 (42): 41452-41461. ( PubMed , DOI )

  3. Kenya Honda, Shinya Sakaguchi, Chigusa Nakajima, Ai Watanabe, Hideyuki Yanai, Misako Matsumoto, Toshiaki Ohteki, Tsuneyasu Kaisho, Akinori Takaoka, Shizuo Akira, Tsukasa Seya, Tadatsugu Taniguchi: Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection. Proc Natl Acad Sci USA. 2003.09; 100 (19): 10872-10877. ( PubMed , DOI )

  4. Kaisa Holmberg, Sanjeev Mariathasan, Toshiaki Ohteki, Pamela S Ohashi, Nicholas R J Gascoigne: TCR binding kinetics measured with MHC class I tetramers reveal a positive selecting peptide with relatively high affinity for TCR. J Immunol. 2003.09; 171 (5): 2427-2434. ( PubMed )

  5. Toshimasa Yamauchi, Junji Kamon, Yusuke Ito, Atsushi Tsuchida, Takehiko Yokomizo, Shunbun Kita, Takuya Sugiyama, Makoto Miyagishi, Kazuo Hara, Masaki Tsunoda, Koji Murakami, Toshiaki Ohteki, Shoko Uchida, Sato Takekawa, Hironori Waki, Nelson H Tsuno, Yoichi Shibata, Yasuo Terauchi, Philippe Froguel, Kazuyuki Tobe, Shigeo Koyasu, Kazunari Taira, Toshio Kitamura, Takao Shimizu, Ryozo Nagai, Takashi Kadowaki: Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature. 2003.06; 423 (6941): 762-769. ( PubMed , DOI )

  6. Okuda T, Hattori H, Takeuchi S, Shimizu J, Ueda H, Palvimo JJ, Kanazawa I, Kawano H, Nakagawa M, Okazawa H: PQBP-1 transgenic mice show a late-onset motor neuron disease-like phenotype. Hum Mol Genet. 2003.04; 12 (7): 711-725. ( PubMed , DOI )

  7. Harumi Suzuki, Satoshi Matsuda, Yasuo Terauchi, Mari Fujiwara, Toshiaki Ohteki, Tomoichiro Asano, Timothy W Behrens, Taku Kouro, Kiyoshi Takatsu, Takashi Kadowaki, Shigeo Koyasu: PI3K and Btk differentially regulate B cell antigen receptor-mediated signal transduction. Nat Immunol. 2003.03; 4 (3): 280-286. ( PubMed , DOI )

  8. Samuel D Saibil, Toshiaki Ohteki, Forest M White, Mark Luscher, Arsen Zakarian, Alisha Elford, Jeffery Shabanowitz, Hiroshi Nishina, Patrice Hugo, Josef Penninger, Brian Barber, Donald F Hunt, Pamela S Ohashi: Weak agonist self-peptides promote selection and tuning of virus-specific T cells. Eur J Immunol. 2003.03; 33 (3): 685-696. ( PubMed , DOI )

  1. Yukie Murata, Toshiaki Ohteki, Shigeo Koyasu, Junji Hamuro: IFN-gamma and pro-inflammatory cytokine production by antigen-presenting cells is dictated by intracellular thiol redox status regulated by oxygen tension. Eur J Immunol. 2002.10; 32 (10): 2866-2873. ( PubMed , DOI )

  2. Enokido Y, Maruoka H, Hatanaka H, Kanazawa I, Okazawa H: PQBP-1 increases vulnerability to low potassium stress and represses transcription in primary cerebellar neurons Biochem. Biophys. Res. Commun. 2002.06; 294 (2): 268-271. ( PubMed , DOI )

  3. Toshiaki Ohteki: Critical role for IL-15 in innate immunity. Curr Mol Med. 2002.06; 2 (4): 371-380. ( PubMed )

  4. Okazawa H, Rich T, Chang A, Lin X, Waragai M, Kajikawa M, Enokido Y, Komuro A, Kato S, Shibata M, Hatanaka H, Mouradian MM, Sudol M, Kanazawa I: Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death. Neuron. 2002.05; 34 (5): 701-713. ( PubMed , DOI )

  5. Ueda H, Goto J, Hashida H, Lin X, Oyanagi K, Kawano H, Zoghbi HY, Kanazawa I, Okazawa H: Enhanced SUMOylation in polyglutamine diseases. Biochem Biophys Res Commun. 2002.04; 293 (1): 307-313. ( PubMed , DOI )

  6. Kristine M Garza, Kim J McKall-Faienza, Toshiaki Otheki, Arsen Zakarian, Bernhard Odermatt, Pamela S Ohashi: Enhanced T cell responses contribute to the genetic predisposition of CD8-mediated spontaneous autoimmunity. Eur J Immunol. 2002.03; 32 (3): 885-894. ( PubMed , DOI )

  1. T Ohteki, K Suzue, C Maki, T Ota, S Koyasu: Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response. Nat Immunol. 2001.12; 2 (12): 1138-1143. ( PubMed , DOI )

  2. T Ohteki, C Maki, S Koyasu: Overexpression of Bcl-2 differentially restores development of thymus-derived CD4-8+ T cells and intestinal intraepithelial T cells in IFN-regulatory factor-1-deficient mice. J Immunol. 2001.06; 166 (11): 6509-6513. ( PubMed )

  3. A Suzuki, M T Yamaguchi, T Ohteki, T Sasaki, T Kaisho, Y Kimura, R Yoshida, A Wakeham, T Higuchi, M Fukumoto, T Tsubata, P S Ohashi, S Koyasu, J M Penninger, T Nakano, T W Mak: T cell-specific loss of Pten leads to defects in central and peripheral tolerance. Immunity. 2001.05; 14 (5): 523-534. ( PubMed )

  4. T Ohteki, S Koyasu: Role of antigen-presenting cells in innate immune system. Arch Immunol Ther Exp (Warsz.). 2001.01; 49 Suppl 1 S47-S52. ( PubMed )

  1. Shoji M, Iwakami N, Takeuchi S, Waragai M, Suzuki M, Kanazawa I, Lippa CF, Ono S, Okazawa H: JNK activation is associated with intracellular beta-amyloid accumulation. Brain Res Mol Brain Res. 2000.12; 85 (1-2): 221-233. ( PubMed , DOI )

  2. T Ohteki, M Parsons, A Zakarian, R G Jones, L T Nguyen, J R Woodgett, P S Ohashi: Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3. J Exp Med. 2000.07; 192 (1): 99-104. ( PubMed )

  3. Waragai M, Junn E, Kajikawa M, Takeuchi S, Kanazawa I, Shibata M, Mouradian MM, Okazawa H: PQBP-1/Npw38, a nuclear protein binding to the polyglutamine tract, interacts with U5-15kD/dim1p via the carboxyl-terminal domain. Biochem Biophys Res Commun. 2000.07; 273 (2): 592-595. ( PubMed , DOI )

  1. Takeuchi S, I mafuku I, Waragai M, Roth C, Kanazawa I, Buettner R, Mouradian MM, Okazawa H : AP-2beta represses D(1A) dopamine receptor gene transcription in neuro2a cells Molecular Brain Research. 1999.12; 74 (1-2): 208-216. ( PubMed , DOI )

  2. Imafuku I, Masaki T, Waragai M, Takeuchi S, Kawabata M, Hirai S, Ohno S, Nee LE, Lippa CF, Kanazawa I, Imagawa M, Okazawa H: Presenilin 1 suppresses the function of c-Jun homodimers via interaction with QM/Jif-1. J Cell Biol. 1999.10; 147 (1): 121-134. ( PubMed , DOI )

  3. T Ohteki, A Hessel, M F Bachmann, A Zakarian, E Sebzda, M S Tsao, K McKall-Faienza, B Odermatt, P S Ohashi: Identification of a cross-reactive self ligand in virus-mediated autoimmunity. Eur J Immunol. 1999.09; 29 (9): 2886-2896. ( PubMed , DOI )

  4. T Ohteki, T Fukao, K Suzue, C Maki, M Ito, M Nakamura, S Koyasu: Interleukin 12-dependent interferon gamma production by CD8alpha+ lymphoid dendritic cells. J Exp Med. 1999.06; 189 (12): 1981-1986. ( PubMed )

  5. Waragai M, Lammers CH, Takeuchi S, Imafuku I, Udagawa Y, Kanazawa I, Kawabata M, Mouradian MM, Okazawa H: PQBP-1, a novel polyglutamine tract-binding protein, inhibits transcription activation by Brn-2 and affects cell survival. Hum Mol Genet. 1999.06; 8 (6): 977-987. ( PubMed , DOI )

  6. T Ohteki, C Maki, S Koyasu, T W Mak, P S Ohashi: Cutting edge: LFA-1 is required for liver NK1.1+TCR alpha beta+ cell development: evidence that liver NK1.1+TCR alpha beta+ cells originate from multiple pathways. J Immunol. 1999.04; 162 (7): 3753-3756. ( PubMed )

  7. E Sebzda, S Mariathasan, T Ohteki, R Jones, M F Bachmann, P S Ohashi: Selection of the T cell repertoire. Annu Rev Immunol. 1999.01; 17 829-874. ( PubMed , DOI )

  1. Imafuku I, Waragai M, Takeuchi S, Kanazawa I, Kawabata M, Mouradian MM, Okazawa H: Polar amino acid-rich sequences bind to polyglutamine tracts. Biochem Biophys Res Commun. 1998.12; 253 (1): 16-20. ( PubMed , DOI )

  2. S Mariathasan, M F Bachmann, D Bouchard, T Ohteki, P S Ohashi: Degree of TCR internalization and Ca2+ flux correlates with thymocyte selection. J Immunol. 1998.12; 161 (11): 6030-6037. ( PubMed )

  3. Skala H, Porteu A, Thomas M, Szajnert MF, Okazawa H, Kahn A, Phan-Dinh-Tuy F: Upstream elements involved in vivo in activation of the brain-specific rat aldolase C gene. Role of binding sites for POU and winged helix proteins J Biol Chem. 1998.11; 273 (48): 31806-31814. ( PubMed , DOI )

  4. T Ohteki, H Yoshida, T Matsuyama, G S Duncan, T W Mak, P S Ohashi: The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+ T) cells, natural killer cells, and intestinal intraepithelial T cells. J Exp Med. 1998.03; 187 (6): 967-972. ( PubMed )

  5. H Yoshida, H Nishina, H Takimoto, L E Marengère, A C Wakeham, D Bouchard, Y Y Kong, T Ohteki, A Shahinian, M Bachmann, P S Ohashi, J M Penninger, G R Crabtree, T W Mak: The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production. Immunity. 1998.01; 8 (1): 115-124. ( PubMed )

  1. T Ohteki, S Ho, H Suzuki, T W Mak, P S Ohashi: Role for IL-15/IL-15 receptor beta-chain in natural killer 1.1+ T cell receptor-alpha beta+ cell development. J Immunol. 1997.12; 159 (12): 5931-5935. ( PubMed )

  2. M F Bachmann, T Ohteki, K M Faienza, A Zakarian, D Kägi, D E Speiser, P S Ohashi: Altered peptide ligands trigger perforin- rather than Fas-dependent cell lysis. J Immunol. 1997.11; 159 (9): 4165-4170. ( PubMed )

  3. Waragai M, Imafuku I, Takeuchi S, Kanazawa I, Oyama F, Udagawa Y, Kawabata M, Okazawa H: Presenilin 1 binds to amyloid precursor protein directly. Biochem Biophys Res Commun. 1997.10; 239 (2): 480-482. ( PubMed , DOI )

  4. M Shimamura, T Ohteki, U Beutner, H R MacDonald: Lack of directed V alpha 14-J alpha 281 rearrangements in NK1+ T cells. Eur J Immunol. 1997.06; 27 (6): 1576-1579. ( PubMed , DOI )

  5. M Shimamura, T Ohteki, P Launois, A M Garcia, H R MacDonald: Thymus-independent generation of NK1+ T cells in vitro from fetal liver precursors. J Immunol. 1997.04; 158 (8): 3682-3689. ( PubMed )

  6. U Beutner, P Launois, T Ohteki, J A Louis, H R MacDonald: Natural killer-like T cells develop in SJL mice despite genetically distinct defects in NK1.1 expression and in inducible interleukin-4 production. Eur J Immunol. 1997.04; 27 (4): 928-934. ( PubMed , DOI )

  1. DE Speiser, E Sebzda, T Ohteki, M F Bachmann, K Pfeffer, TW Mak, PS Ohashi: Tumor necrosis factor receptor p55 mediates deletion of peripheral cytotoxic T lymphocytes in vivo. Eur. J. Immunol.. 1996.12; 26 (12): 3055-3060. ( PubMed , DOI )

  2. Okazawa H, Imafuku I, Minowa MT, Kanazawa I, Hamada H, Mouradian MM: Regulation of striatal D1A dopamine receptor gene transcription by Brn-4. Proc Natl Acad Sci USA. 1996.10; 93 (21): 11933-11938. ( PubMed , DOI )

  3. Imafuku I, Kamei M, Kanazawa I, Mouradian MM, Okazawa H : POU transcription factors differentially regulates the D1A dopamine receptor gene in cultured cells Biochem. Biophys. Res. Commun. 1996.05; 222 (3): 736-741. ( PubMed , DOI )

  4. T Ohteki, H R MacDonald: Stringent V beta requirement for the development of NK1.1+ T cell receptor-alpha/beta+ cells in mouse liver. J. Exp. Med.. 1996.03; 183 (3): 1277-1282. ( PubMed )

  5. Okazawa H, Shimizu J, Kamei M, Imafuku I, Hamada H, Kanazawa I: Bcl-2 inhibits retinoic acid-induced apoptosis during the neural differentiation of embryonal stem cells. J Cell Biol. 1996.03; 132 (5): 955-968. ( PubMed , DOI )

  6. T Ohteki, A Wilson, S Verbeek, H R MacDonald, H Clevers: Selectively impaired development of intestinal T cell receptor gamma delta+ cells and liver CD4+ NK1+ T cell receptor alpha beta+ cells in T cell factor-1-deficient mice. Eur. J. Immunol.. 1996.02; 26 (2): 351-355. ( PubMed , DOI )

  1. P Launois, T Ohteki, K Swihart, H R MacDonald, J A Louis: In susceptible mice, Leishmania major induce very rapid interleukin-4 production by CD4+ T cells which are NK1.1-. Eur. J. Immunol.. 1995.12; 25 (12): 3298-3307. ( PubMed , DOI )

  2. P R Walker, T Ohteki, J A Lopez, H R MacDonald, J L Maryanski: Distinct phenotypes of antigen-selected CD8 T cells emerge at different stages of an in vivo immune response. J. Immunol.. 1995.10; 155 (7): 3443-3452. ( PubMed )

  3. T Ohteki, M Iwamoto, S Izui, H R MacDonald: Reduced development of CD4-8-B220+ T cells but normal autoantibody production in lpr/lpr mice lacking major histocompatibility complex class I molecules. Eur. J. Immunol.. 1995.01; 25 (1): 37-41. ( PubMed , DOI )

  1. T Ohteki, H R MacDonald: Major histocompatibility complex class I related molecules control the development of CD4+8- and CD4-8- subsets of natural killer 1.1+ T cell receptor-alpha/beta+ cells in the liver of mice. J. Exp. Med.. 1994.08; 180 (2): 699-704. ( PubMed )

  2. Okazawa H, Kamei M, Imafuku I, Kanazawa I: Gene regulation of trkB and trkC in the chick retina by light/darkness exposure. Oncogene. 1994.07; 9 (7): 1813-1818. ( PubMed )

  3. J P Rosat, M Schreyer, T Ohteki, G A Waanders, H R MacDonald, J A Louis: Selective expansion of activated V delta 4+ cells during experimental infection of mice with Leishmania major. Eur. J. Immunol.. 1994.02; 24 (2): 496-499. ( PubMed , DOI )

  1. Shimazaki T, Okazawa H, Fujii H, Ikeda M, Tamai K, McKay RD, Muramatsu M, Hamada H: Hybrid cell extinction and re-expression of Oct-3 function correlates with differentiation potential. EMBO J. 1993.12; 12 (12): 4489-4498. ( PubMed , DOI )

  2. Dechant G, Biffo S, Okazawa H, Kolbeck R, Pottgiesser J, Barde YA: Expression and binding characteristics of the BDNF receptor chick trkB. Development. 1993.10; 119 (2): 545-558. ( PubMed , DOI )

  3. Okazawa H, Kamei M and Kanazawa I : Molecular cloning and expression of a novel truncated form of chicken trkC FEBS letters. 1993.08; 329 (1-2): 171-177. ( PubMed , DOI )

  4. Okazawa H, Nishiyama K, Kamei M, Washizaki S, Murayama S, Kwak S and Kanazawa I: Trk immunoreactivity at neuronal dendrite and cell body Biochem. Biophys. Res. Commun. 1993.07; 194 (2): 683-690. ( PubMed , DOI )

  5. T Ohteki, H R MacDonald: Expression of the CD28 costimulatory molecule on subsets of murine intestinal intraepithelial lymphocytes correlates with lineage and responsiveness. Eur. J. Immunol.. 1993.06; 23 (6): 1251-1255. ( PubMed , DOI )

  6. N Koyamada, T Ohteki, T Abo, T Fukumori, N Ohkouchi, S Satomi, Y Taguchi, A Kusumi, S Mori, K Kumagai: Induction of specific tolerance by hepatic double-negative CD4-8- alpha beta T cells of mice immunized with allogeneic cells via the portal vein in vivo [corrected]. Cell. Immunol.. 1993.06; 149 (1): 107-116. ( PubMed )

  7. T Ohteki, S Okamoto, M Nakamura, E Nemoto, K Kumagai: Elevated production of interleukin 6 by hepatic MNC correlates with ICAM-1 expression on the hepatic sinusoidal endothelial cells in autoimmune MRL/lpr mice. Immunol. Lett.. 1993.05; 36 (2): 145-152. ( PubMed )

  8. T Ohteki, T Abo, A Kusumi, T Sasaki, S Shibata, S Seki, K Kumagai: Age-associated increase of CD5+ B cells in the liver of autoimmune (NZB x NZW) F1 mice. Microbiol. Immunol.. 1993.01; 37 (3): 221-228. ( PubMed )

  1. T Iiai, H Watanabe, S Seki, K Sugiura, K Hirokawa, M Utsuyama, H Takahashi-Iwanaga, T Iwanaga, T Ohteki, T Abo: Ontogeny and development of extrathymic T cells in mouse liver. Immunology. 1992.12; 77 (4): 556-563. ( PubMed )

  2. Okazawa H, Murata M, Watanabe M, Kamei M and Kanazawa I : Dopaminergic stimulation up-regulates the in vivo expression of brain derived neurotrophic factor (BDNF) in the striatum FEBS letters . 1992.11; 313 (2): 138-142. ( PubMed , DOI )

  3. A Kusumi, T Abo, T Masuda, K Sugiura, S Seki, T Ohteki, R Okuyama, K Kumagai: Lymphotoxin activates hepatic T cells and simultaneously induces profound thymic atrophy. Immunology. 1992.10; 77 (2): 177-184. ( PubMed )

  4. T Ohteki, R Okuyama, S Seki, T Abo, K Sugiura, A Kusumi, T Ohmori, H Watanabe, K Kumagai: Age-dependent increase of extrathymic T cells in the liver and their appearance in the periphery of older mice. J. Immunol.. 1992.09; 149 (5): 1562-1570. ( PubMed )

  5. T Abo, A Kusumi, S Seki, T Ohteki, K Sugiura, T Masuda, H Rikiishi, T Iiai, K Kumagai: Activation of extrathymic T cells in the liver and reciprocal inactivation of intrathymic T cells by bacterial stimulation. Cell. Immunol.. 1992.06; 142 (1): 125-136. ( PubMed )

  6. R Okuyama, T Abo, S Seki, T Ohteki, K Sugiura, A Kusumi, K Kumagai: Estrogen administration activates extrathymic T cell differentiation in the liver. J. Exp. Med.. 1992.03; 175 (3): 661-669. ( PubMed )

  7. H Watanabe, K Ohtsuka, M Kimura, Y Ikarashi, K Ohmori, A Kusumi, T Ohteki, S Seki, T Abo: Details of an isolation method for hepatic lymphocytes in mice. J. Immunol. Methods. 1992.02; 146 (2): 145-154. ( PubMed )

  1. T Masuda, T Ohteki, T Abo, S Seki, S Nose, H Nagura, K Kumagai: Expansion of the population of double negative CD4-8- T alpha beta-cells in the liver is a common feature of autoimmune mice. J. Immunol.. 1991.11; 147 (9): 2907-2912. ( PubMed )

  2. S Seki, T Abo, K Sugiura, T Ohteki, T Kobata, H Yagita, K Okumura, H Rikiishi, T Masuda, K Kumagai: Reciprocal T cell responses in the liver and thymus of mice injected with syngeneic tumor cells. Cell. Immunol.. 1991.10; 137 (1): 46-60. ( PubMed )

  3. Okazawa H, Okamoto K, Ishino F, Ishino-Kaneko T, Takeda S, Toyoda Y, Muramatsu M, Hamada H: The oct3 gene, a gene for an embryonic transcription factor, is controlled by a retinoic acid repressible enhancer. EMBO J. 1991.10; 10 (10): 2997-3005. ( PubMed , DOI )

  4. T Abo, T Ohteki, S Seki, N Koyamada, Y Yoshikai, T Masuda, H Rikiishi, K Kumagai: The appearance of T cells bearing self-reactive T cell receptor in the livers of mice injected with bacteria. J. Exp. Med.. 1991.08; 174 (2): 417-424. ( PubMed )

  5. S Seki, T Abo, T Ohteki, K Sugiura, K Kumagai: Unusual alpha beta-T cells expanded in autoimmune lpr mice are probably a counterpart of normal T cells in the liver. J. Immunol.. 1991.08; 147 (4): 1214-1221. ( PubMed )

  6. T Ohteki, T Abo, S Seki, T Kobata, H Yagita, K Okumura, K Kumagai: Predominant appearance of gamma/delta T lymphocytes in the liver of mice after birth. Eur. J. Immunol.. 1991.07; 21 (7): 1733-1740. ( PubMed , DOI )

  1. J Satoh, H Seino, S Shintani, S Tanaka, T Ohteki, T Masuda, T Nobunaga, T Toyota: Inhibition of type 1 diabetes in BB rats with recombinant human tumor necrosis factor-alpha. J. Immunol.. 1990.09; 145 (5): 1395-1399. ( PubMed )

  2. S Seki, T Abo, T Masuda, T Ohteki, A Kanno, K Takeda, H Rikiishi, H Nagura, K Kumagai: Identification of activated T cell receptor gamma delta lymphocytes in the liver of tumor-bearing hosts. J. Clin. Invest.. 1990.08; 86 (2): 409-415. ( PubMed , DOI )

  3. T Ohteki, S Seki, T Abo, K Kumagai: Liver is a possible site for the proliferation of abnormal CD3+4-8- double-negative lymphocytes in autoimmune MRL-lpr/lpr mice. J. Exp. Med.. 1990.07; 172 (1): 7-12. ( PubMed )

  4. Okamoto K, Okazawa H, Okuda A, Sakai M, Muramatsu M, Hamada H: A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell. 1990.02; 60 (3): 461-472. ( PubMed , DOI )

  5. Toshiaki Ohteki: Analysis of lymphoproliferative disorders in autoimmune model mouse (MRL-lpr/lpr) accompanying Sjögren’s syndrome. Tohoku Univ Dent J. 1990.01; 9 73-82.

  1. J Satoh, H Seino, T Abo, S Tanaka, S Shintani, S Ohta, K Tamura, T Sawai, T Nobunaga, T Oteki: Recombinant human tumor necrosis factor alpha suppresses autoimmune diabetes in nonobese diabetic mice. J. Clin. Invest.. 1989.10; 84 (4): 1345-1348. ( PubMed , DOI )

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  4. 松田 憲之: パーキンソン病を抑制するPINK1/Parkin依存性マイトファジーの分子メカニズム ブレインサイエンス・レビュー. 2024.04; 2024 15-37. ( 医中誌 )

  5. 藤田 慶大, 岡澤 均: DNA損傷の修復と神経変性 AnnualReview神経2024. 2024.03; 35-41.

  1. 岡澤 均: 脊髄小脳失調症1型における遺伝子治療 脳神経内科. 2023.10; 99 (4): 542-550.

  2. 岡澤 均: DNA損傷と修復の疾患病態における役割 BIOClinica. 2023.08; 38 (9): 4-5.

  3. 田中 ひかり, 岡澤 均: DNA損傷と神経疾患 BIOClinica. 2023.08; 38 (9): 12-16.

  4. 田中 ひかり, 岡澤 均: 神経変性疾患における自然免疫応答 臨床免疫・アレルギー科. 2023.07; 80 (1): 56-62.

  5. 樗木 俊聡: プラズマサイトイド樹状細胞は何者か? 臨床免疫・アレルギー科. 2023.07; 80 (1): 43-48.

  6. 金 美花, 岡澤 均: ウイルス感染症と類似する神経変性疾患の炎症応答メカニズム 炎症と免疫. 2023.04; 31 (3): 26-33.

  7. 藤田 慶大, 岡澤 均: 脊髄小脳失調症1型 遺伝子治療開発研究ハンドブック第 2 版. 2023.04; 524-530.

  8. 松田 憲之: Parkinから考察するマイトファジー測定系の現状と問題点 実験医学. 2023.03; 41 (5): 682-687. ( 医中誌 )

  1. 岡澤 均, 藤田 慶大: 3塩基リピート病1(Huntington‘sDisease) メディカル・サイエンス・ダイジェスト. 2022.09; 48 (10): 3-5.

  2. 岡澤 均: 加齢, 変性疾患とDNA損傷修復不全 老年精神医学雑誌. 2022.06; 33 (6): 603-617.

  3. 望月 秀樹, 青木 正志, 池中 建介, 井上 治久, 岩坪 威, 宇川 義一, 岡澤 均, 小野 賢二郎, 小野寺 理, 北川 一夫, 齊藤 祐子, 下畑 享良, 髙橋 良輔, 戸田 達史, 中原 仁, 松本 理器, 水澤 英洋, 三井 純, 村山 繁雄, 勝野 雅央, 日本神経学会将来構想委員会, 青木 吉嗣, 石浦 浩之, 和泉 唯信, 小池 春樹, 島田 斉, 髙橋 祐二, 徳田 隆彦, 中嶋 秀人, 波田野 琢, 三澤 園子, 渡辺 宏久: 脳神経疾患克服に向けた研究推進の提言2020,各論I(方法論別) 臨床神経学. 2022.06; 62 (6): 429-442. ( PubMed , DOI )

  4. 望月 秀樹, 青木 正志, 池中 建介, 井上 治久, 岩坪 威, 宇川 義一, 岡澤 均, 小野 賢二郎, 小野寺 理, 北川 一夫, 齊藤 祐子, 下畑 享良, 髙橋 良輔, 戸田 達史, 中原 仁, 松本 理器, 水澤 英洋, 三井 純, 村山 繁雄, 勝野 雅央, 日本神経学会将来構想委員会, 青木 吉嗣, 石浦 浩之, 和泉 唯信, 小池 春樹, 島田 斉, 髙橋 祐二, 徳田 隆彦, 中嶋 秀人, 波田野 琢, 三澤 園子, 渡辺 宏久: 脳神経疾患克服に向けた研究推進の提言2020,各論II(疾患群別) 臨床神経学. 2022.06; 62 (6): 443-457. ( PubMed , DOI )

  5. 泉 湧太, 金山 剛士, 樗木 俊聡: 【シン・マクロファージ あらゆる疾患を制御する機能的多様性】(第2章)病気とマクロファージの多様性を知る14の方法 マクロファージ分化経路とその治療標的としての可能性 実験医学. 2022.03; 40 (5): 704-709. ( 医中誌 )

  6. 泉 湧太, 金山 剛士, 樗木 俊聡: マクロファージ分化経路とその治療標的としての可能性 実験医学. 2022.03; 40 (5): 705-709.

  7. 岡澤 均: Alzheimer病態に於ける細胞内アミロイド,細胞死,細胞外アミロイド凝縮の時間的関係 神経治療学. 2022.01; 38 (3): 347-352.

  8. 岡澤 均: 臨床をベースとする基礎研究者のキャリアパスとリーダーシップ BRAIN and NERVE. 2022.01; 74 (1): 59-62. ( DOI )

  1. 樗木 俊聡: 樹状細胞への運命決定 呼吸器内科. 2021.12; 40 (6): 632-636.

  2. 望月 秀樹, 青木 正志, 池中 建介, 井上 治久, 岩坪 威, 宇川 義一, 岡澤 均, 小野 賢二郎, 小野寺 理, 北川 一夫, 齊藤 祐子, 下畑 享良, 髙橋 良輔, 戸田 達史, 中原 仁, 松本 理器, 水澤 英洋, 三井 純, 村山 繁雄, 勝野 雅央, 青木 吉嗣, 石浦 浩之, 和泉 唯信, 小池 春樹, 島田 斉, 髙橋 祐二, 徳田 隆彦, 中嶋 秀人, 波田野 琢, 三澤 園子, 渡辺 宏久: 脳神経疾患克服に向けた研究推進の提言 2020,総論 臨床神経学. 2021.11; 61 (11): 709-721. ( PubMed , DOI )

  3. 樗木 俊聡: 第49回日本免疫学会学術集会 感染 炎症 免疫. 2021.10; 51 (2): 63-65.

  4. 味岡 逸樹, 岡澤 均: 東京医科歯科大学脳統合機能研究センター(CBIR) Clinical Neuroscience. 2021.10; 39 (10): 1232-1235.

  5. 佐藤 卓, 樗木 俊聡: 組織再生を担う腸幹細胞の維持と機能 生化学. 2021.08; 93 (4): 503-511.

  6. 松田 憲之: 【どうして自分だけ狙われる?選択的オートファジー 既成概念を覆す分子機構と生理作用】マイトファジーにおける選択性の起源 実験医学. 2021.08; 39 (13): 2052-2059. ( 医中誌 )

  7. 泉 湧太, 金山 剛士, 樗木 俊聡: 単球・マクロファージの分化経路 血液内科. 2021.07; 83 (1): 1-7.

  8. 佐藤 卓, 樗木 俊聡: 腸管上皮細胞におけるインターフェロンの役割 臨床免疫・アレルギー科. 2021.06; 75 (6): 759-764.

  9. 金山 剛士, 樗木 俊聡: 【免疫系の暴走 サイトカインストーム 多様な疾患で生じる全身性の炎症反応その共通機構から病態を理解する】高サイトカイン血症と単球・マクロファージ 実験医学. 2021.03; 39 (4): 512-516. ( 医中誌 )

  10. 金山 剛士, 樗木 俊聡: 高サイトカイン血症と単球・マクロファージ 実験医学. 2021.03; 39 (4): 512-516.

  11. 佐藤卓、樗木俊聡: 腸幹細胞の維持にはIFNシグナルの抑制が重要 ネイチャー・ダイジェスト. 2021.02; 18 (2): 22-25.

  12. 佐藤 卓, 樗木 俊聡: 腸幹細胞の維持にはIFNシグナルの抑制が重要 natureダイジェスト. 2021.02; 18 (2): 22-25.

  13. 泉 湧太, 金山 剛士, 川村 俊輔, 樗木 俊聡: 単球・マクロファージの分化経路 血液内科. 2021.01; 83 (1): 1-7.

  1. 岡澤 均: アルツハイマー病態に於ける細胞内アミロイド、細胞死、細胞外アミロイド凝縮の時間的関係 神経治療学. 2020.10; 37 (6): S119.

  2. 田中 ひかり, 近藤 和, 陳 西貴, 本間 秀典, 田川 一彦, 藤田 慶大, 岡澤 均: 発達障害原因遺伝子PQBP1はアルツハイマー病態を制御する Dementia Japan. 2020.10; 34 (4): 527. ( 医中誌 )

  3. 田中 ひかり, 本間 秀典, 藤田 慶大, 近藤 和, Jin Xiaocen, 田川 一彦, 岡澤 均: YAP依存的ネクローシスは超早期アルツハイマー病態を制御する Dementia Japan. 2020.10; 34 (4): 473. ( 医中誌 )

  4. 石川駿、佐藤卓、村川泰裕、樗木俊聡: NET-CAGE法を用いたエンハンサー解析と病態解明 月刊 糖尿病・内分泌代謝科. 2020.10; 51 (4):

  5. 樗木 俊聡: 特集:マクロファージの功罪 医学のあゆみ. 2020.06; 273 (10): 925.

  6. 田中 ひかり, 岡澤 均: 【神経変性疾患の治療開発の現状-新たな戦略構築の基盤をめざして】各分野の動向 ダウンストリームを治療する 神経細胞死 医学のあゆみ. 2020.04; 273 (1): 93-97. ( 医中誌 )

  7. 田中 ひかり, 岡澤 均: ダウンストリームを治療する 医学のあゆみ. 2020.04; 273 (1): 93-97.

  8. 田中 ひかり, 岡澤 均: 脊髄小脳失調症 Clinical Neuroscience . 2020.03; 38 (3): 365-368.

  9. 田中 ひかり, 岡澤 均: 【よくわかる遺伝子治療-実用化の現状と展望】遺伝子治療各論 脊髄小脳失調症 Clinical Neuroscience. 2020.03; 38 (3): 365-368. ( 医中誌 )

  1. 金山 剛士: 免疫老化における胸腺マクロファージの機能解析 上原記念生命科学財団研究報告集. 2019.12; 33 1-4. ( 医中誌 )

  2. 岡澤 均: アルツハイマー病の遺伝子治療の可能性 認知神経科学. 2019.12; 21 155-165.

  3. 田中 ひかり, 近藤 和, 陳 西貴, 田川 一彦, Kerever Aurelian, 青木 茂樹, 斉藤 貴志, 西道 隆臣, 村松 慎一, 藤田 慶大, 岡澤 均: 発達障害原因遺伝子PQBP1はアルツハイマー病態を制御する 臨床神経学. 2019.11; 59 (Suppl.): S461. ( 医中誌 )

  4. 松田 憲之: 【マルチモードオートファジー-広がり続ける自食作用の世界-】PINK1/Parkin依存性マイトファジーにおけるParkin活性化の分子機構 生化学. 2019.10; 91 (5): 626-633. ( 医中誌 )

  5. 近藤 和, 藤田 慶大, 岡澤 均: 脊髄小脳失調症とYAPdeltaC Clinical Neuroscience . 2019.08; 37 (8): 1007-1010.

  6. 小内 伸幸, 樗木 俊聡: アレルギーにおける樹状細胞の役割 実験医学. 2019.06; 37 (10): 42-48.

  7. 田中 ひかり, 岡澤 均: 発達障害原因遺伝子PQBP1はアルツハイマー病態を制御する ケミカルバイオロジー. 2019.06; 12 (1): 12.

  8. 松田 憲之: 【臓器連環による生体恒常性の破綻と疾患 すべての医学者・生命科学者に捧ぐ】(第1章)細胞における動的恒常性とその破綻 細胞の恒常性維持を担う動的なユビキチン修飾 実験医学. 2019.05; 37 (7): 1038-1050. ( 医中誌 )

  1. 岡澤 均: 総論 シナプス研究を加速する基礎臨床連携 細胞. 2018.12; 50 (14): 2-4.

  2. 藤田 慶大, 岡澤 均: 変性疾患におけるシナプス異常の新知見 細胞. 2018.12; 50 (14): 25-28.

  3. 樗木俊聡: 総論 マクロファージの可塑性と組織適応 月刊「細胞」2019年1月号 vol.51, No.1, 2019(通巻674号). 2018.12; 51 (674): 6-7.

  4. 松田 憲之, 山野 晃史: 【蛋白質代謝医学-構造・機能の研究から臨床応用まで】蛋白質の品質管理とその制御 マイトファジー PINK1とParkinによるミトコンドリア蛋白質の品質管理 医学のあゆみ. 2018.12; 267 (13): 1056-1062. ( 医中誌 )

  5. 松田 憲之: 【タンパク質・核酸の分子修飾】細胞質/オルガネラでの分子修飾 タンパク質機能・品質管理 ユビキチンリン酸化 生体の科学. 2018.10; 69 (5): 456-457. ( 医中誌 )

  6. 藤田 慶大, 陳 西貴, 本間 秀典, 田川 一彦, 岡澤 均: アルツハイマー病と前頭側頭葉変性症に共通する異常タウリン酸化とシナプス障害 Dementia Japan. 2018.09; 32 (3): 431. ( 医中誌 )

  7. 藤田 慶大, 岡澤 均: 凝集前病態の解明に基づくアルツハイマー病の新規DMT 開発 アルツハイマー病 . 2018.08; 157-164.

  8. 小内 伸幸, 樗木 俊聡: 単球由来マクロファージの前駆細胞 炎症と免疫. 2018.05; 26 (3): 17-24.

  9. 松田 憲之: 【パーキンソン病(第2版)-基礎・臨床研究のアップデート-】病因 その他の因子 タンパク質・オルガネラ・アルデヒド分解系 日本臨床. 2018.05; 76 (増刊4 パーキンソン病): 156-161. ( 医中誌 )

  10. 小内伸幸,川村俊輔,樗木俊聡: 単球由来マクロファージの前駆細胞 炎症と免疫. 2018.04; 26(3) (5月): 17-24.

  11. 樗木 俊聡: ヒトにおける共通単球前駆細胞の同定 感染・炎症・免疫. 2018.04; 48 (1): 18-25.

  12. 金山剛士, 篠原眞理: 分泌型および細胞内型のオステオポンチンによるミエロイド系細胞とリンパ球系細胞とのバランスの制御 臨床免疫・アレルギー科 . 2018.03; 63 (3): 219-224.

  13. 金山 剛士, 篠原 眞理: 【リンパ球の分化と機能制御】 分泌型および細胞内型のオステオポンチンによるミエロイド系細胞とリンパ球系細胞のバランス制御 臨床免疫・アレルギー科. 2018.03; 69 (3): 219-224. ( 医中誌 )

  14. 本間 秀典, 岡澤 均: 【ニューロジェネティクス新時代 次世代シークエンサーが拓く新しい世界】筋疾患・神経疾患のジェネティクス ハンチントン病 Clinical Neuroscience. 2018.02; 36 (2): 213-215. ( 医中誌 )

  15. 本間 秀典, 岡澤 均: 【ニューロジェネティクス新時代 次世代シークエンサーが拓く新しい世界】 筋疾患・神経疾患のジェネティクス ハンチントン病 Clinical Neuroscience. 2018.02; 36 (2): 213-215. ( 医中誌 )

  16. 本間 秀典, 岡澤 均: ハンチントン病 Clinical Neuroscience. 2018.02; 36 (2): 213-215.

  17. 津田 浩史, 岡澤 均: Huntington病 神経疾患最新の治療 2018-2020. 2018.01; 200-202.

  18. 樗木 俊聡: ヒト単球前駆細胞cMoPの同定-マウスcMoPのカウンターパート- 臨床血液. 2018; 59 (6): 812-818. ( PubMed , DOI )

  1. 佐藤 裕介, 尾勝 圭, 佐伯 泰, 山野 晃史, 松田 憲之, 海保 愛, 山形 敦史, 伊藤 桜子, 石川 稔, 橋本 祐一, 田中 啓二, 深井 周也: ユビキチン・コード:細胞内の最も難解な暗号を読む USP30によるLys6結合型ユビキチン鎖特異的切断機構の構造的基盤 生命科学系学会合同年次大会. 2017.12; 2017年度 [4AW13-6]. ( 医中誌 )

  2. 平石 萌, 小谷野 史香, 久永 眞市, 中田 和人, 田中 啓二, 松田 憲之: Parkin機能喪失に由来するパーキンソン病モデルマウスの作製と解析 生命科学系学会合同年次大会. 2017.12; 2017年度 [2P-1068]. ( 医中誌 )

  3. 小島 和華, 山野 晃史, 木村 まゆみ, Bruno Queliconi, 田中 啓二, 松田 憲之: DJ-1の局在解析から見出す非典型的ミトコンドリア局在化シグナル 生命科学系学会合同年次大会. 2017.12; 2017年度 [1P-0324]. ( 医中誌 )

  4. 小内 伸幸, 樗木 俊聡: 血球貪食症候群の発症機構と免疫学的意義 血液内科. 2017.11; 75 (5): 591-597.

  5. 藤田 慶大, 本木 和美, 田川 一彦, 陳 西貴, 本間 秀典, 岡澤 均: アルツハイマー病において神経突起変性を誘発するHMGB1-MARCKSリン酸化シグナル Dementia Japan. 2017.10; 31 (4): 562. ( 医中誌 )

  6. 藤田 慶大, 岡澤 均: ポリグルタミン病 運動失調のみかた、考えかた . 2017.09; 251-260.

  7. 遠藤 努, 伊藤 甲雄, 森本 純子, 金山 剛士, 太田 大地, 池末 昌弘, 今 重之, 小野寺 智洋, 高橋 大介, 岩崎 倫政, 上出 利光: Syndecan-4 regulates development of autoimmune arthritis by modulating B cell migration and germinal center formation 自己免疫性関節炎におけるシンデカン-4の機能解析 北海道整形災害外科学会雑誌. 2017.08; 59 (1): 11-17. ( 医中誌 )

  8. 小谷野史香、松田憲之: リン酸化ユビキチンを基軸としたPINK1とParkinによる不良ミトコンドリアの排除機構 2017医学のあゆみ パーキンソン病の新展開―発症の分子機構と新規治療. 2017.08; 262 (6): 603-608.

  9. 小谷野 史香, 松田 憲之: 【パーキンソン病の新展開-発症の分子機構と新規治療】分子機構解明の新しい展開 リン酸化ユビキチンを基軸としたPINK1とParkinによる不良ミトコンドリアの排除機構 医学のあゆみ. 2017.08; 262 (6): 603-608. ( 医中誌 )

  10. 藤田 慶大, 岡澤 均: HMGB1補充による脊髄小脳失調症1型に対する分子標的治療 Brain Nerve. 2017.08; 69 (8): 925-932. ( PubMed , DOI )

  11. 藤田 慶大, 岡澤 均: アミロイド凝集前の超早期病態とその抑制 認知症. 2017.07; 35 (12): 198-203.

  12. 川村俊輔、樗木俊聡: ヒトにおける共通単球前駆細胞の同定 ライフサイエンス 新着論文レビュー. 2017.06; ( DOI )

  13. 樗木俊聡: マクロファージの分化と多様性(「免疫学のABC」第2回) 分子リウマチ治療 2017年2月号 Vol 10. No.1. 2017.05;

  14. 松田 憲之, 服部 信孝, Halliday Glenda, Obeso Jose A, 髙橋 良輔, 長谷川 成人: 座談会 α-シヌクレイノパチーとマイトファジー研究の現在と今後の展望 Frontiers in Parkinson disease. 2017.02; 10 (1): 7-16.

  15. 高橋 良輔, 松田 憲之, 服部 信孝, Halliday Glenda, 長谷川 成人: α-シヌクレイノパチーとマイトファジー研究の現在と今後の展望 Frontiers in Parkinson Disease. 2017.02; 10 (1): 7-16. ( 医中誌 )

  16. 小谷野史香, 松田憲之: パーキンソン病の新展開-発症の分子機構と新規治療 分子機構解明の新しい展開 リン酸化ユビキチンを基軸としたPINK1とParkinによる不良ミトコンドリアの排除機構 医学のあゆみ. 2017; 262 (6):

  17. 小谷野史香, 田中啓二, 松田憲之: ミトコンドリア品質管理におけるParkinの基質特異性について 日本生化学会大会(Web). 2017; 90th

  18. 吉田雪子, 安田さや香, 藤田敏治, 濱崎万穂, 村上有沙, 川脇純子, 岩井一宏, 佐伯泰, 吉森保, 松田憲之, 田中啓二: SCFFBXO27による損傷リソソームから細胞質へ露出した糖蛋白質のユビキチン化はリソファジーの引き金となる 日本生化学会大会(Web). 2017; 90th ROMBUNNO.4LT01‐08(3P‐0149) (WEB ONLY)-0149)]. ( 医中誌 )

  1. 岡澤 均: アルツハイマー病の“超早期”治療を可能にする分子メカニズムと治療薬開発 ファームステージ. 2016.12;

  2. 小内伸幸、樗木俊聡 : 樹状細胞前駆細胞および樹状細胞サブセットのソーティング 実験医学 別冊 最強のステップUPシリーズ 新版!フローサイトメトリー. 2016.09; 229-240.

  3. 岡澤 均, 本木 和美: 1990年以後の神経栄養因子臨床試験からの知見と教訓 生体の科学 . 2016.08; 67 (4): 291-295.

  4. 藤田 慶大, 岡澤 均: 変性疾患の共通分子病態 生体の科学. 2016.08; 67 (4): 309-313.

  5. 岡澤 均: 「認知症・神経変性疾患の克服への挑戦」によせて 生体の科学. 2016.08; 67 (4): 280.

  6. 川村俊輔、小内伸幸、樗木俊聡: マクロファージの発生・分化 JSI Newletter vol.24 No.2 特集「マクロファージ」日本免疫学会会報. 2016.04; 16.

  7. 樗木俊聡: マクロファージ・樹状細胞の起源と多様性 医学のあゆみ 259巻5号 マクロファージのすべて. 2016.01; 347-352.

  1. 樗木俊聡、小内伸幸: 制御性血球貪食樹状細胞 炎症と免疫 2015年11月号. 2015.10; 60-64.

  2. 松田憲之, 小谷野史香: Phos-Tag電気泳動による“パーキンソン病の発症を抑えるリン酸化”の解析 電気泳動(Web). 2015.10; 59 (2):

  3. 藤田 慶大, 岡澤 均: 神経変性疾患の共通病態としてのDNA損傷修復異常 Annual Review神経2015. 2015.01; 65-72.

  4. 松田憲之, 尾勝圭, 小谷野史香, 田中啓二: PINK1が異常ミトコンドリアの外膜に特異的に局在化する仕組み 日本細胞生物学会大会要旨集. 2015; 67th

  1. 手塚裕之, 安倍由紀子, 黒田聖子, 樗木俊聡: IgA生産を制御する樹状細胞サブセット 臨床免疫・アレルギー科. 2014.12; 62 (6): 593-599.

  2. 樗木俊聡、小内伸幸: 樹状細胞の分化経路 臨床免疫・アレルギー科 62 (6). 2014.12; 569-574.

  3. 田村 拓也, 岡澤 均: 神経変性疾患の細胞死とHippo pathway —神経変性はHippo pathwayで制御されるか?— 医学のあゆみ. 2014.11; 251 (5): 449-454.

  4. 樗木俊聡: 血球貪食減少の新たな視点 臨床血液. 2014.10; 55 (10): 49-53.

  5. 小内伸幸、樗木俊聡: plasmacytoid dendritic cellの分化とその制御 医学のあゆみ. 2014.09; 250 (11): 1044-1045.

  6. 大八木秀明、小内伸幸、澤田賢一、樗木俊聡: 血球貪食症候群の病態解明の進歩:単球に由来する樹状細胞による血球の貪食と新しい免疫寛容誘導の仕組み 血液内科 第69巻第2号. 2014.08; 279-284.

  7. 小谷野 史香, 松田 憲之: 【マイトファジー-基礎から疾患との関連まで】ParkinとPINK1の制御機構 医学のあゆみ. 2014.08; 250 (6-7): 459-465. ( 医中誌 )

  8. 大八木秀明、小内伸幸、澤田賢一、樗木俊聡: 樹状細胞による免疫寛容誘導の最新情報:単球に由来する樹状細胞による血球の貪食と新しい免疫寛容誘導の仕組み Surgery Frontier 2014 (21) 3 特集:生体防御における免疫反応の新知見. 2014.06; 19-24.

  9. 上羽悟史、小内伸幸、松島綱治、樗木俊聡: 樹状細胞・マクロファージサブセットの起源と生体内移動 実験医学 増刊 炎症 32(17). 2014.06; 31-37.

  10. 小谷野史香, 松田憲之: PINK1によってリン酸化されたユビキチンはParkinを活性化する 日本分子生物学会年会プログラム・要旨集(Web). 2014; 37th

  11. 小谷野史香, 小谷野史香, 松田憲之: マイトファジー-基礎から疾患との関連まで ParkinとPINK1の制御機構 医学のあゆみ. 2014; 250 (6/7):

  1. 樗木俊聡、小内伸幸: 樹状細胞の新しい前駆細胞 炎症と免疫. 2013.12; 22 (1): 41-46.

  2. 小内伸幸、樗木俊聡: 単球に由来する樹状細胞による血球の貪食と免疫反応の制御 ライフサイエンス 新着論文レビュー. 2013.10; ( DOI )

  3. 樗木俊聡: 樹状細胞、NK細胞の基礎知識 HORMONE FRONTEER IN GYNECOLOGY 特集 生殖と自然免疫 Vol 20, No1.. 2013.06; 21-26.

  4. 樗木俊聡: 単球由来樹状細胞による過剰免疫応答の制御 細胞工学. 2013.06; 32 (12): 1211-1214.

  5. 小内伸幸、樗木俊聡: 形質細胞様樹状細胞への卓越した分化能をもつ新しい樹状細胞前駆細胞の発見 ライフサイエンス 新着論文レビュー. 2013.05; ( DOI )

  6. 小内伸幸、大八木秀明 澤田賢一、樗木俊聡: 樹状細胞による新しい免疫寛容誘導の仕組み 医薬ジャーナル 2013年2月号(Vol.49, No.2). 2013.01; 95-100.

  7. 久住呂友紀, 井口正寛, 尾勝圭, 小谷野史香, 木村まゆみ, 鈴木則宏, 田中啓二, 松田憲之: Parkin遺伝子はチオエステル中間体を形成する 日本神経学会学術大会プログラム・抄録集. 2013; 54th

  1. 樗木俊聡、手塚裕之: 腸管粘膜防御機構を担うIgA抗体の新たな産生機構(形質細胞様樹状細胞のユニークな役割) 炎症と免疫 20. 2012.06; 178-182.

  2. 樗木俊聡、手塚裕之: pDCによる新たなIgA生産誘導メカニズム 医学のあゆみ 240. 2012.06; 185-183.

  3. 手塚裕之、安部由紀子、樗木俊聡: T細胞非依存性IgA生産における樹状細胞の役割 臨床免疫•アレルギー科 58(3). 2012.05; 283-289.

  4. 尾勝圭, 岡敏彦, 井口正寛, 今村健二, 小迫英尊, 谷直紀, 木村まゆみ, 呉越, 小谷野史香, 福永裕子, 谷口寿章, 三原勝芳, 松田憲之, 田中啓二: PINK1のリン酸化はParkinによるミトコンドリア品質維持を制御する 日本生化学会大会(Web). 2012; 85th

  5. 小谷野史香, 井口正寛, 尾勝圭, 松田憲之, 田中啓二: マウス初代神経細胞におけるミトコンドリア品質維持とPINK1/Parkin 日本生化学会大会(Web). 2012; 85th

  6. 小谷野史香, 尾勝圭, 松田憲之, 田中啓二: ミトコンドリア-ストレスからパーキンソン病を解明する 臨床ストレス応答学会大会抄録集. 2012; 7th

  1. 手塚裕之、安部由紀子、樗木俊聡: 形質細胞様樹状細胞によるT細胞非依存性IgA生産誘導機構 臨床免疫•アレルギー科 55. 2011.06; 687-692.

  2. 樗木俊聡: pDCによる新たなIgA生産誘導の仕組み 感染 炎症 免疫 Vol.41.No.4. 2011.06; 83-84.

  3. 樗木俊聡、手塚裕之: T細胞非依存性IgA産生誘導における形質細胞様樹状細胞の質的優位性 細胞工学30 (No.4). 2011.03; 376-380.

  1. 樗木俊聡、手塚裕之: TNF/iNOS産生DCとIgA分泌 医学のあゆみ 234(5). 2010.06; 453-457.

  2. 樗木俊聡、佐藤 卓: インターフェロンによる造血幹細胞の運命決定制御 実験医学 増刊 28(12). 2010.06; 152-156.

  3. 佐藤 卓、樗木俊聡: インターフェロンと白血病幹細胞 血液フロンティア 20. 2010.06; 139-147.

  1. 田村 拓也, 岡澤 均: PolII特異的阻害薬、-アマニチンが引き起こす非特異的で緩慢な細胞死(TRIAD) 日本ケミカルバイオロジー学会機関紙「ケミカルバイオロジー(Chemical Biology)」. 2009.12; 4 (2): 3.

  2. 手塚裕之・安部由紀子・樗木俊聡: 消化管粘膜におけるIgA生産機構 炎症と免疫 17. 2009.10; 86-92.

  3. 樗木俊聡・佐藤卓: 眠れる造血幹細胞を目覚めさせるインターフェロン DENTAL DIAMOND 34. 2009.06; 80-85.

  4. 手塚裕之・安部由紀子・樗木俊聡: 粘膜関連リンパ組織におけるT細胞非依存性IgAクラススイッチ誘導機構 臨床免疫・アレルギー科 52. 2009.06; 422-430.

  5. 岡澤 均: TRIAD Brain and nerve . 2009.03; 61 285-292. ( PubMed )

  1. 手塚裕之・安部由紀子・樗木俊聡: 腸管における樹状細胞のトラフィッキングとIgA生産誘導機構 臨床免疫・アレルギー科 49(1). 2008.10; 10-15.

  2. 安部由紀子、手塚裕之、樗木俊聡: 粘膜樹状細胞によるIgAクラススイッチ誘導機構 感染・炎症・免疫 38(3). 2008.06; 271-274.

  3. 小内伸幸・樗木俊聡: 樹状細胞によるTh分化制御 分子細胞治療 7(3). 2008.06; 162-170.

  4. 樗木俊聡、安部由紀子、手塚裕之: 樹状細胞によるIgA生産誘導機構の新知見 炎症と免疫 16(2). 2008.03; 209-214.

  5. 手塚裕之、安部由紀子、樗木俊聡: IgAクラススイッチを誘導するパイエル板樹状細胞 臨床免疫・アレルギー科 50. 2008.03; 216-221.

  6. 手塚裕之、安部由紀子、樗木俊聡: 腸管でのIgA生産を司るTNF/iNOS生産性樹状細胞とその作用機構 生体の科学 59(4). 2008.03; 268-274.

  7. 手塚裕之、安部由紀子、樗木俊聡: 消化管粘膜での免疫応答における樹状細胞の役割ー小腸粘膜樹状細胞によるクラススイッチ制御 実験医学 26(20). 2008.02; 3236-3242.

  8. 手塚裕之、安部由紀子、樗木俊聡: 腸管粘膜樹状細胞によるIgAクラススイッチ制御ー腸内常在菌の役割 医学のあゆみ 227(5). 2008.02; 326-331.

  1. 樗木俊聡・多田浩之: IL-15による炎症反応の制御 感染・炎症・免疫, 37(1). 2007.10; 10-16.

  2. 桑島精一・樗木俊聡: CpGオリゴヌクレオチドによる樹状細胞からのIL-12生産メカニズム 臨床免疫・アレルギー科, 47(5). 2007.06; 603-609.

  3. 手塚裕之、安部由紀子、樗木俊聡: 粘膜TiP-DCによるIgA生産誘導機構 臨床免疫・アレルギー科, 47(6). 2007.06; 619-624.

  4. 多田浩之・樗木俊聡: 樹状細胞からのIL-15生産と炎症 臨床免疫・アレルギー科, 48(3). 2007.06; 340-346.

  5. 手塚裕之、安部由紀子、樗木俊聡: 樹状細胞によるIgAクラススイッチ誘導機構 臨床免疫・アレルギー科, 48(3). 2007.06; 230-235.

  6. 小内伸幸、小内亜矢、樗木俊聡、: 樹状細胞サブセットの分化経路 生化学, 79(12). 2007.02; 1143-1148.

  7. 岡澤 均: 神経変性はアポトーシスか?--YAPdeltaCによる神経細胞死制御 生化学. 2007.02; 79 157-162. ( PubMed )

  1. 樗木俊聡・石田和人: [私達の研究] 免疫疾患におけるインターロイキン-15の役割 化学療法の領域 22. 2006.09; 95-99.

  2. 佐藤 卓、樗木俊聡: 樹状細胞のサイトカインを介する生体防御機構 臨床免疫45. 2006.09; 192-196.

  3. 樗木俊聡: CpG DNAによる免疫賦活機構の新知見 東北のコロニー 33. 2006.06; 3-9.

  4. 佐藤 卓、木俊聡: 消化管免疫24. 生体防御におけるIELおよび腸管DCの機能 別冊医学のあゆみ 消化器疾患 states of arts I. 消化管(食道・胃・腸)Ver. 3. 2006.02; 89-92.

  5. 桑島精一、樗木俊聡: IL-15による自然免疫賦活メカニズム 実験医学増刊号 免疫研究最前線2007 24. 2006.02; 3154-3160.

  1. 多田浩之、樗木俊聡: 自然免疫と獲得免疫の基礎:自然免疫と感染免疫における樹状細胞の役割 最新医学 60. 2005.11; 597-604.

  2. 佐藤 卓、樗木俊聡: 感染からの回避機構.わかりやすい免疫疾患 日本医師会雑誌 134 特別号. 2005.10; 76-77.

  3. 佐藤 卓、樗木俊聡: 感染におけるTh1/Th2反応 Surgery Frontier 12. 2005.06; 31-36.

  4. 手塚裕之、樗木俊聡: 樹状細胞が生産するサイトカインによるB細胞の機能調節 臨床免疫 44. 2005.03; 109-112.

  1. 樗木俊聡: IL-15の免疫反応および免疫疾患における役割 Molecular Medicine 41 (臨時増刊号). 2004.11; 262-268.

  1. 樗木俊聡: 樹状細胞の活性化におけるIL-15の役割 現代医療 35. 2003.03; 1807-1812.

  2. 樗木俊聡: 自然免疫と獲得免疫の連携における樹状細胞の役割 医学のあゆみ 205. 2003.03; 57-61.

  1. 樗木俊聡: IL-15による樹状細胞機能の調節 2002.03; 2139-2144.

  2. 樗木俊聡: インターロイキン-15による生体防御調節機構 東北大学歯学雑誌 21. 2002.03; 53-60.

  1. 樗木俊聡、小安重夫: 樹状細胞によるTh1/Th2バランスの制御と疾病 Molecular Medicine 38. 2001.11; 1356-1362.

  2. 樗木俊聡、小安重夫: 樹状細胞の分化・機能発現とサイトカイン制御 Molecular Medicine 臨時増刊号「免疫2001-02」. 2001.03; 180-188.

  3. 樗木俊聡: 樹状細胞、マクロファージの機能とIFNg、IL-15 臨床免疫 36. 2001.03; 204-210.

  4. 樗木俊聡: 肝NK1.1+TCRab+ 細胞の由来と分化 臨床免疫 35. 2001.03; 657-660.

  1. 樗木俊聡: MACSによる樹状細胞の単離と機能解析 臨床免疫 34. 2000.10; 848-854.

  2. 小安重夫、樗木俊聡、深尾太郎、鈴江一友: 自然免疫における樹状細胞の機能 細胞 32. 2000.06; 212-215.

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  2. 樗木俊聡、小安重夫: NK細胞、NKT細胞の分化 実験医学 17. 1999.06; 39-43.

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  2. 樗木俊聡、新田康隆、熊谷勝男: 癌転移の臓器特異性を決定する接着分子と増殖因子 実験医学 10. 1992.06; 24-29.

  1. 安保徹、樗木俊聡: gdT細胞の誘導 臨床免疫 23. 1991.06; 1113-1121.

  1. 樗木俊聡、安保徹、熊谷勝男: 樗木俊聡・安保徹・熊谷勝男「腸管感染とgdT細胞 Medical Immunology 19. 1990.06; 439-445.

  2. 樗木俊聡、熊谷勝男: サイトカインネットワーク 1990.06; 1012-1013.

  3. 樗木俊聡、安保徹、熊谷勝男: 樗木俊聡・安保徹・熊谷勝男「肝類洞と腸管上皮内gdT細胞 Human Cell 3. 1990.04; 233-240.

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