Takeshi Tsubata. Cross-talk between complement pathways and immune system. 2021.09.10

Takeshi Tsubata. Immunogenic Peptides Derived from SARS-CoV2. 19th Sugadai Symposium 2021.09.03 On-line

N. Numoto, K. Hirata, C. Akatsu, T. Tsubata, N. Ito. Molecular mechanism of self-antigen recognition by the ligand binding domain of B cell inhibitory co-receptor CD72. 25TH Congress and General Assembly of the International Union of Crystallography 2021.08.14 WEB

Amin Alborzian Deh Sheikh, Takeshi Tsubata 他. A Guillain-Barré syndrome-associated SIGLEC10 rare variant impairs its recognition of gangliosides. 第85回日本インターフェロン・ サイトカイン学会学術集会 2021.05.21 WEB

Takeshi Tsubata. Inhibitory B cell co-receptors and autoimmune diseases. The 85th Annual Meeting of the Japanese Society of Interferon & Cytokine Research 2021.05.21

Takeshi Tsubata. The SHP-1-activating inhibitory co-receptor CD22 paradoxically augments BCR signaling in immunodeficient B cells. The 14th International Conference on Protein Phosphatase 2020.12.10 Kobe + WEB

Takeshi Tsubata. Regulation of B cells and autoimmune diseases. The 48th Annual Meeting of the Japanese Society for Immunology (JSI) 2019.12.13 Hamamatsu, SHIZUOKA

Chizuru Akatsu, Quan-Zhen Li, Hideharu Sekine, Teizo Fujita, Takeshi Tsubata. The inhibitory B cell co-receptor CD72 recognizes various lupus self-antigens including C1q and inhibits B cell responses to these self-antigen . The 48th Annual Meeting of the Japanese Society for Immunology (JSI) 2019.12.12 Hamamatsu, SHIZUOKA

Ying Wang, Jun Liu, Ermeng Xiong, Chizuru Akatsu, Takeshi Tsubata, Ji-Yang Wang. LAPTM5 mediates anti-IgM-induced apoptosis in immature B cells. The 48th Annual Meeting of the Japanese Society for Immunology (JSI) 2019.12.12 Hamamatsu, SHIZUOKA

Yang-Yang Feng, Jun Liu, Ji-Yang Wang, Takeshi Tsubata . Essential role of late redoxosome in BCR ligation-induced B cell activation. The 48th Annual Meeting of the Japanese Society for Immunology (JSI) 2019.12.12 Hamamatsu, SHIZUOKA

Kyoko Nishida, Akihiro Kimura, Takeshi Tsubata, Harumi Suzuki. The anti-oxidative enzyme NAD(P)H quinone oxidoreductase1 promotes Th17 cells differentiation by protecting oxidative stress. The 48th Annual Meeting of the Japanese Society for Immunology (JSI) 2019.12.12 Hamamatsu, SHIZUOKA

Liu, J., Qian, J., Xiong, E., Zhang, L., Wang, Y., Chu, Y., Tsubata, T. and Wang, J.-Y.. Role of the IgM Fc receptor in marginal zone B cell development and function. The 48th Annual Meeting of the Japanese Society for Immunology (JSI) 2019.12.12 Hamamatsu, SHIZUOKA

Xiong, E., Cui, C., Min, Q., Liu, J., Lai, N., Wang, Y., Matsumoto, R., Takahashi, D., Hase, K., Shinkura, R., Tsubata, T. and Wang, J.-Y.. MZB1 promotes the secretion of J chain-containing IgA and is critical for the suppression of gut inflammation. The 48th Annual Meeting of the Japanese Society for Immunology (JSI) 2019.12.12 Hamamatsu, SHIZUOKA

Tang, Y., Lai, N., Xiong, E., Ouchida, R., Sun, J., Hikida, M., Tsubata, T., Wang, Y. and Wang, J.-Y.. Distinct roles of B cell novel protein 1 in B cell development and activation. The 48th Annual Meeting of the Japanese Society for Immunology (JSI) 2019.12.12 Hamamatsu, SHIZUOKA

Takeshi Tsubata. Regulation of the immune response to nucleic acids and systemic lupuserythematosus. The 1st “Wuxi talents” Symposium of Experimental Research Center of the First People’s Hospital of Huaihua 2019.11.29 Huaihua, CHINA

Takeshi Tsubata. SHP-1 (PTPN6) regulates development of SLE through CD72. The 4th Taiwan-Japan Bilateral Conference on Protein Phosphatase 2019.11.15 Taipei,TAIWAN

Takeshi Tsubata. Inhibitory B cell co-receptors and autoimmune diseases. Mini-symposium on Protein Structure and Function 2019.10.03 Taipei,TAIWAN

YangYang Feng, Miao Tang, Mitsuhiro Suzuki, Chinthika Gunasekara, Yuki Anbe, Yuichi Hiraoka, Jun Liu, JiYang Wang, Takeshi Tsubata. Essential role of NOX3-mediated endosomal production of ROS in maintenance of sustained B cell receptor signaling and B cell proliferation. The 92nd Annual Meeting of the Japanese Biochemical Society 2019.09.18 Yokohama, KANAGAWA

Yang-Yang Feng, Miao Tang, Mitsuhiro Suzuki, Chinthika Gunasekara, Yuki Anbe, Yuichi Hiraoka, Jun Liu, Helmut Grasberger, Mamoru Ohkita, Yasuo Matsumura, Ji-Yang Wang, and Takeshi Tsubata. Essential role of NADPH oxidase-dependent production of reactive oxygen species in maintenance of sustained B cell receptor signaling and B cell proliferation. The 28th Annual Meeting of the Japanese Society for Cell Death Research 2019.07.13 TOKYO

Long　Wang、Endo　Ayaka、Takematsu　Hiromu、Fedder　Thomas、Tsubata　Takeshi. Development of anti-CD22 antibody that inhibits ligand binding of CD22. The Regular Meeting of the Japanese Biochemical Society Kanto Branch 2019.06.22 Yokohama, KANAGAWA

Yangyang Feng, Jun Liu, Helmut Grasberger, Ji-Yang Wang, Takeshi Tsubata. Essential role of NADPH oxidase-dependent production of reactive oxygen species in maintenance of sustained B cell receptor signaling and B cell proliferation . The 47th Annual Meeting of the Japanese Society for Immunology 2018.12.10 Fukuoka

Xuexin Li, Soha Gomaa Ramadan Abdel Salam, Matthew Routledge, Yuki Hitomi, Susumu Kusunoki, Takeshi Tsubata. Significant associations of human SIGLEC10 polymorphisms with susceptibility to Guillain-Barré syndrome. The 47th Annual Meeting of the Japanese Society for Immunology 2018.12.10 Fukuoka

Kyoko Nishida, Akihiro Kimura, Takeshi Tsubata, Harumi Suzuki. NQO1 regulates pathogenisity of Th17 cells by suppressing IL-10 production. The 47th Annual Meeting of the Japanese Society for Immunology 2018.12.10 Fukuoka

Chizuru Akatsu, Quan-Zhen Li, and Takeshi Tsubata. Roles of CD72 in the regulation of autoantibody production and type 1 interferon production in autoimmune disease. The 47th Annual Meeting of the Japanese Society for Immunology 2018.12.10 Fukuoka

Chizuru Akatsu, Xuexin Li, Susumu Kusunoki, Takeshi Tsuabta. SHP-1-activating B lymphocyte co-receptors and autoimmune diseases. The 47th Annual Meeting of the Japanese Society for Immunology 2018.12.10 Fukuoka

Takeshi Tsuabta. Ligand recognition determines functional properties of inhibitory B cell co-receptors. International Symposium on B cells 2018.12.07 Shanghai,China

Chinthika Gunasekara、Kozo Watanabe、Takeshi Tsubata. Reactive oxygen species play a role in endosomal B cell antigen receptor signaling. 7th Federation of Immunological Societies of Asia-Oceania (FIMSA) Congress 2018 2018.11.10 Bangkok,Thailand

Yang-Yang Feng, Miao Tang, Mitsuhiro Suzuki, Jun Liu, Helmut Grasberger, Ji-Yang Wang and Takeshi Tsubata. Essential role of NADPH oxidases in BCR signaling and B cell proliferation. Workshop on Frontiers in Phosphatase Research and Drug Discovery (ICPP13) 2018.10.23 Tokyo

Amin Alborzian Deh Sheikh, Chizuru Akatsu, Hideharu Ishida and Takeshi Tsubata. The role of ligand recognition of SHP-1 activating receptor CD22 in the regulation of B cell tonic signaling. Workshop on Frontiers in Phosphatase Research and Drug Discovery (ICPP13) 2018.10.23 Tokyo

Moe Endo, Chizuru Akatsu, Quan-Zhen Li, Chengsong Zhu, Teizo Fujita, Hideharu Sekine, Takeshi Tsubata. Ligand recognition of the SHP-1-activating inhibitory B cell co-receptor CD72. Workshop on Frontiers in Phosphatase Research and Drug Discovery (ICPP13) 2018.10.23 Tokyo

Chizuru Akatsu, Xuexin Li, Susumu Kusunoki, Takeshi Tsuabta. SHP-1-activating B lymphocyte co-receptors and autoimmune diseases. Workshop on Frontiers in Phosphatase Research and Drug Discovery (ICPP13) 2018.10.23 Tokyo

Takeshi Tsubata. Essential role of NADPH oxidase-dependent production of reactive oxygen species in maintenance of sustained B cell receptor signaling and B cell proliferation. 2018.06.25 Freiburg, Germany

Yang-Yang Feng, Miao Tang, Mitsuhiro Suzuki, Jun Liu, Helmut Grasberger, Mamoru Ohkita, Yasuo Matsumura, Ji-Yang Wang, and Takeshi Tsubata. Role of NADPH oxidases in BCR signaling and B cell proliferation. The Regular Meeting of the Japanese Biochemical Society Kanto Branchranch 2018.06.23 Saitama

Amin Alborzian Deh Sheikh, Chizuru Akatsu, Hideharu Ishida and Takeshi Tsubata. The role of CD22 glycan cis-ligands in the regulation of B cell tonic signaling. The Regular Meeting of the Japanese Biochemical Society Kanto Branch 2018.06.23 Saitama

Takeshi Tsubata. The Inhibitory B Cell Co-Receptor CD72 Regulates Tolerance to Self Nucleic Acids Crucial for Development of Systemic Lupus Erythematosus. Keystone Symposia, B cells: Mechanisms in Immunity and Autoimmunity 2018.06.21 Dresden, Germany

Takeshi Tsubata. Endogenous ligands of inhibitory B cell co-receptors. 2018.06.15 Berlin, Germany

Takeshi Tsubata. Endogenous ligands of inhibitory B lymphocyte co-receptors. 2018.06.14 Zürich, Switzerland

Takeshi Tsubata. Inhibitory B cell co-receptors and autoimmune diseases. 45th IMSUT Founding Commemorative Symposium "A new era of medical researches created by disease models" 2018.06.01 Tokyo

MEDZHIDOV Nazim, TAKATA Toshitaro, SUZUKI Mitsuhiro, ICHINOSE Shizuko, YAMAGUCHI Hirofumi, ARAKAWA Satoko, SHIMIZU Shigeomi, TSUBATA Takeshi.. Role of poor B cell receptor ubiquitination in efficient antigen presentation. The 46th Annual Meeting of The Japanese Society for Immunology 2017.12.14 Sendai

Feng Yangyang, Rengarajan Sundararaman, Tang Miao, Tsubata Takeshi. Role of NADPH oxidases in BCR ligation-induced ROS production and activation. The 46th Annual Meeting of The Japanese Society for Immunology 2017.12.14 Sendai

Kyoko Nishida, Akihiro Kimura, Takeshi Tsubata, Harumi Suzuki. NQO1 play a pathogenic role in autoimmune diseases through the suppression of IL-10 production in Th17 cells. The 46th Annual Meeting of The Japanese Society for Immunology 2017.12.12 Sendai

Takeshi Tsubata, Hongrui Yang, Chizuru Akatsu. CD72 recognizes RNA-related self-antigens and prevents autoimmunity. The 46th Annual Meeting of The Japanese Society for Immunology 2017.12.12 Sendai

Chizuru Akatsu, Amin Alborzian Deh Sheikh, Takeshi Tsubata. Role of CD45 (PTPRC) in the regulation of SHP-1 (PTPN6)-activating receptor CD22. The 3rd Japan-Taiwan Bilateral Conference on Protein Phosphatase 2017.11.19 Sendai

Chizuru Akatsu, Hongrui Yang and Takeshi Tsubata,. The Inhibitory B Cell Co-Receptor CD72 Regulates B Cell Response to Self Nucleic Acids Crucial for Development of SLE. Korean Association of Immunologists (KAI) International Meeting 2017 2017.11.10 Seoul

Takeshi Tsubata. Inhibitory B cell co-receptor and autoimmunity. Seoul National University School of Dentistry 2017.11.08 Seoul

Takeshi Tsubata. Inhibitory B cell co-receptor CD72 regulates self-tolerance through SHP-1 activation. University of Freiburg 2017.10.11 Freiburg, Germany

Nobutaka Numoto,Chizuru Akatsu,Kenro Shinagawa,Takeshi Tsubata,Nobutoshi Ito. Charge distribution regulates the ligand-binding affinity of B cell inhibitory receptor CD72. The 55th Annual Meeting of the Biophysical Society of Japan 2017.09.20 Kumamoto

MEDZHIDOV Nazim, TAKATA Toshitaro, SUZUKI Mitsuhiro, ICHINOSE Shizuko, TSUBATA Takeshi. Distinct ubiquitination level and sorting of the B cell receptor. The Regular Meeting of the Japanese Biochemical Society, Kanto Branch 2017 2017.06.17 Tokyo

Amin Alborzian-Deh-Sheikh, Chizuru Akatsu, Hideharu Ishida2, and Takeshi Tsubata. Cis-ligand dependent and independent interaction of receptor type protein tyrosine phosphatase CD45 with B cell inhibitory receptor CD22. The Regular Meeting of the Japanese Biochemical Society, Kanto Branch 2017 2017.06.17 Tokyo

Feng Yangyang, Rengarajan Sundararaman, Tang Miao, Tsubata Takeshi. Role of prolonged ROS in B cell receptor signaling. The Regular Meeting of the Japanese Biochemical Society, Kanto Branch 2017 2017.06.17 Tokyo

Mohammad Aslam, Martin Weigert and Takeshi Tsubata. Regulation of self-reactive B cells by CD72 and Fas . 11th International Symposium of The Institute Network"Frontiers in Biomedical Sciences" 2017.01.26 Tokushima

Medzhidov Nazim, Takata toshitaro, Suzuki Mitsuhiro, Ichinose Shizuko, Tsubata Takeshi. Distinct ubiquitination level and sorting of B cell receptor. The 45th Annual Meeting of The Japanese Society for Immunology (JSI) 2016.12.06 OKINAWA

Takeshi Tsubata. Development of a novel glycomimetic with unique immunological activity. . 15th Surugadai International Symposium　"Current Status and Future of Drug Discovery" 2016.11.29 TOKYO

Takeshi Tsubata. B lymphocytes and autoimmunity. Fudan University School of Basic Medical Sciences, China 2016.11.07 SHANGHAI,CHINA

Chizuru Akatsu,Kenro Shinagawa, Nobutaka Numoto, Zhihong Liu, Mohommad Aslam, Nobutoshi Ito, Takeshi Tsubata. B cells reactive to Sm/RNP, a lupus-related self-antigen. 12th International Conference on Protein Phosphatase (ICPP12) 2016.10.28 OSAKA

Tsubata, T.. B lymphocyte co-receptors and systemic lupus erythematosis. Fudan University 2015.12.16 Shainghai

Aslam, M., Adachi, T. and Tsubata, T.. CD72 regulates self-reactive B cells to nuclear antigens. The 44th Annual Meeting of The Japanese Society for Immunology 2015.11.20 Sapporo

Akatsu, C., Aslam, M., Adachi, T. and Tsubata, T.. Interaction of CD72 and SLE-related antigen negatively regulates self-reactive B cells. The 44th Annual Meeting of The Japanese Society for Immunology 2015.11.20 Sapporo

Chizuru Akatsu, Mohammad Aslam, Takahiro Adachi, and Takeshi Tsubata . Interaction of CD72 and SLE-related antigen negatively regulates self-reactive B cells. The 44th JSI annual meeting 2015.11.20 Sapporo

Onodera, T., Adachi, T., Tsubata, T., Ato, M. and Takahashi, Y.. Visualization of anti-nuclear Ab producing B cells by flow-cytometry in a SLE mouse model. The 44th Annual Meeting of The Japanese Society for Immunology 2015.11.18 Sapporo

Aslam, M., Adachi, T., Weigert, M. G. and Tsubata, T.. CD72 regulates self-reactive B cells to nuclear antigens. The 30th Autoimmune Conference 2015.07.11 Tokyo

Tsubata, T.. CD22-binding synthetic sialosides as a tool to elucidate the role of CD22 cis-ligand and as a novel immunostimulant. 2015.03.23 Freiburg

Tsubata, T.. CD22-binding synthetic sialosides as a tool to elucidate the role of CD22 cis-ligand and as a novel immunostimulant. TRR130 2015.03.18 Erlangen

Tsubata, T.. CD22-binding synthetic sialosides as a tool to elucidate the role of CD22 cis-ligand and as a novel immunostimulant. DRFZ 2015.03.16 Berlin

P. A. Koni., Ren, M., Tsubata, T., Khleif, S., Maverakis, E. and Shimoda, M.. A mouse model for chronic inflammatory diseases spontaneously develops CD4/CD8 double-positive T cell leukemia/lymphoma. . The 54th Midwinter Conference of Immunologists at Asilomar. 2015.01.24 Big Bear Lake, California (USA)

Matsubara, N., Ishida, H. and Tsubata, T.. CD22-binding synthetic sialosides as a tool to elucidate the role of CD22 cis-ligand and as a novel immunostimulan. Medical Research Institute 40th Anniversary, 13th Surugadai International Symposium & Joint Usage/Research Program of Medical Research Institute International Symposium. 2014.11.28 Tokyo

Matsubara, N., Takematsu, H., Ishida, H., Tsubata, T.. Role of CD22/Siglec2 and its ligand in B lymphocyte activation. . Joint annual meeting of SFG &JSCR, Integrating Glycoscience from Biology and Chemistry to Medicine. 2014.11.16 Honolulu, Hawaii (USA)

Matsubara, N., Ishida, H. and Tsubata, T.. Synthetic sialosides that regulate CD22/Siglec-2, a B lymphocyte membrane molecule activating SH2-containing phosphatases.. 11th International Conference on Protein Phosphatase. 2014.11.12 Sendai

Mohammad, A., Kishi Y., Weigert, M. G. and Tsubata, T.. Distinct tolerance mechanisms for anti-DNA and anti-Sm B cells.. The 29th Autoimmune Conference 2014.07.12

Li, Y., Hase, K., Tsubata, T. and Wang, J-Y.. Glia maturation factor-γ regulates marginal zone B cell migration and humoral immune responses.. Annual Meeting of the Japanese Society for Immunology 2013.12.11 Chiba.

Xu. M., Hou. R., Sato-Hayashizaki. A., Man. R-Y., Zhu. C., Wakabayashi. C., Hirose. S., Adachi. T. and Tsubata. T.. Cd72c is a modifier gene that regulates Faslpr-induced autoimmune disease.. Annual Meeting of the Japanese Society for Immunology 2013.12.11 Chiba.

Mohammad, A. and Tsubata, T.. Distinct tolerance mechanisms for anti-DNA and anti-Sm B cells. . Annual Meeting of the Japanese Society for Immunology 2013.12.11 Chiba.

Tsubata, T.. Regulation of B lymphocyte responses and sialic acid-binding immunoglobulin-like lectins (Siglecs). . Glyco Medicine Seminar, IBMS, Academia Sinica, 2013.11.27 Taipei.

Tsubata, T.. SHP-1-activating Receptors in B lymphocytes. . The 2nd Taiwan-Japan Bilateral Conference on Protein Phosphatase 2013.11.27 Hsinchu.

Tsubata, T.. Sialic acids and immune responses. Molecular Frontier Science Conference for Humboltians and DAAD Alumni 2013.09.20 上海

Shimoda. M., Bolduc. A., Takezaki. M., Tsubata. T. and Koni. P-A. . Excess B cell CD40/CD40L signaling promotes CD4 T cell-mediated encephalomyelitis in mice. . Immunology 2013 AAI Annual meeting. 2013.05.03 Honolulu.

Tsubata, T.. CD72c a hapolotype encoding the SHP-1-binding B lymphocyte molecule is a modifier gene for murine lupus. the 10th International Conference on Protein Phosphatase 2013.02.07 東京

Tsubata, T.. CD72C , a hapolotype encoding the SHP-1-binding B lymphocyte molecule, is a modifier gene for murine lupus. the 10th International Conference on Protein Phosphatase 2013.02.07 東京

Tang, M., Takata, T., Tsubata, T.. Time, place and pathway-specific involvement of reactive oxygen species in B cell antigen receptor signaling. . 日本免疫学会学術総会 2013.02.05 神戸

Suganuma, Y., Matsubara, N., Iwayama, Y., Ueki, A., Imamura, A., Ando, H., Tsubata, T., Ishida, H. and Kiso, M.. Synthesis and biological evaluation of the mimics of cis ligand for CD22. The 4th Asian Communication for Glycobiology and Glycotechnology (ACGG) 2012.10.28 Jeju, Korea

Tsubata, T.. Screening of chemical compounds that regulate antibody responses. . 中国医学科学院/北京協和医科大学 2012.03.14 北京、中国

Tsubata, T.. Molecular and Cellular aspects of Autoimmune Diseases. . 中国医科大学 2012.01.09 瀋陽、中国

Tang Miao、高田俊太朗、鍔田武志. Role of Reactive Oxygen Species in B Cell Antigen Receptor Signaling. 第40回日本免疫学会学術集会 2011.11.27 幕張

Tsubata, T.. Development of chemial compounds that regulate specific antibody production.. 中国医学科学院/北京協和医科大学 2011.03.17 北京、中国

Tsubata, T.. Apoptotic deletion of self-reactive B cells in the splenic marginal zone. . The Gwen Knapp Symposium “the Antigen Targets of Autoimmune Disease”, The University of Chicago 2010.10.08 Chicago, USA.

Tsubata, T.. Excess CD40L and autoimmunity.. Immunotherapy Center, Medical College of Georgia 2010.10.06 Augusta, USA.

Tsubata, T.. Apoptotic deletion of marginal zone B cells: a novel tolerance mechanism of pathogenic self-reactive B cells.. Deutsches Rheuma-Forschungszentrum Berlin (DRFZ) 2010.10.04 Berlin, Germany.

Tsubata, T.. Control of infectious diseases by functional modulation of B lymphocytes. . The 8th German-Japanese Immunology Symposium ”Regulation of Immune Response and Disease” 2010.09.26 Cuxhaven, Germany.

Tsubata, T.. Membrane-bound lectins and humoral immunity. International Summer Program 2010 ”Infection and Immunity”, Tokyo Medical and Dental University 2010.09.05 Tokyo.

Kishi, Y., Higuchi, T., Sakamaki, Y., Tsubata, T.. Overexpression of CD40L (CD154) breaks down self-tolerance in spleen in autoantibody-transgenic mice. . 14th International Congress of Immunology 2010.08.22 Kobe

Man, R.-Y., Onodera, T., Komatsu, E., Tsubata, T.. Augmented B Lymphocyte Response to Antigen in the Absence of Antigen-Induced B lymphocyte Signaling in an IgG-Transgenic Mouse Line. . 14th International Congress of Immunology 2010.08.22 Kobe

Hou, R., Sato, A., Lin, Q., Ohtsuji, M., Adachi, T., Hirose, S., Tsubata, T.. Effect of CD72c allotype on SLE susceptibility.. 15th International Congress of Immunology 2010.08.22 Kobe

Abdu-Allah, H. H. M., Ishida, H., Tsubata, T., Kelm, S., Paulson, J. C., Ando, H., Kiso, M.. Design and Synthesis of Novel Sialosides as potent and selective CD22-Inhibitors. . Sialoglyco Meeting 2010 2010.08.21 Potsdam, Germany.

Tsubata, T.. Control of Infectious Diseases by Functional Modulation of B Lymphocyte Lectins. . The 28th Naito Conference on ”Glycan Expression and Regulation [I]:Functions and Disease Mechanisms” 2010.07.27 Kanagawa.

Tsuiji. M., Tanaka. M., Imai. N., Hayashizaki. K., Tsubata. T.. The Immune Response against Capsular Polysaccharides of Streptococcus pneumoniae. . The 28th Naito Conference on ”Glycan Expression and Regulation [I]:Functions and Disease Mechanisms” 2010.07.27 Kanagawa.

Miduo Xu, Rong Hou, Mareki Ohtsuji, Naomi Ohtsuji, Takahiro Adachi, Sachiko Hirose, Takeshi Tsubata. CD72 modulates the development of lupus-like disease in B61pr/pr mice. 第39回日本免疫学会 2009.12.02 大阪

Rong Hou, Mareki Ohtsuji, Naommi Ohtsuji, Li Zhang, Takahiro Adachi, Sachiko Hirose, Takeshi Tsubata. Centromeric interval of chromosome4 derived from C57BL/6 mice accelerates type 1 diabetes in NOD.CD72b congenic mice. 第39回日本免疫学会 2009.12.02 大阪

Man Rong-Yong, Taishi Onodera, Takeshi Tsubata. Ligand-independent high tonic signaling through IgG-BCR induces B-cell receptor signaling defect and enhances B cell response. 第39回日本免疫学会 2009.12.02 大阪

満栄勇、小野寺大志、鍔田武志. Increased tonic B cell antigen receptor signaling but reduced antigen-induced B cell response in transgenic B cells expressing IgG. 第38回日本免疫学会総会・学術集会 2009.12.01 京都

Tsubata, T.. B cell response augmentation by expression of IgG and deficiency in CD22. Annual Symposium of the Korean Association of Immunologists 2009.11.09 Seoul, Korea

Tsubata, T.. Inhibitory B lymphocyte co-receptor CD72 and autoimmunity. C. M. U. (ジュネーブ大学医療センター) 2009.09.18 Geneva, Switzerland

Tsubata, T.. Membrane-bound lectins and humoral immunity. 2ndEuropean Congress of Immunology 2009.09.13 Berlin, Germany

N. Engels, L. M. Koening, C. Heemann, J. Lutz, Tsubata, T., S.Griep, V. Schrader, J. Wienands. The immunoglobulin tail tyrosine of surface IgG and IgE provides antigen receptor-intrinsic costimulation to class-switched B cells. 2ndEuropean Congress of Immunology 2009.09.13 Berlin, Germany

Tsubata, T.. How unresponse, slow response and rapid response of humoral immunity is determined? . ZIBI　International Summer School on Pathogen-Host-Interplay 2009.07.19 Berlin,　Germany

Tsubata, T.. Membrane-bound lectins and humoral immunity. CREST International Symposium “Acquired Immunity and Glycobiology” 2009.03.23 Kazusa, Japan

Wtanabe, K., Tsuchiya, Y., Kawaguchi, Y., Ayame, H., sawada, S., Akiyoshi, K., Tsubata, T.. Self-assembled cationic nanogel-mediated efficient protein delivery in mouse primary T cells. The 5th international Workshop of Kyoto Tcell conference 2009.01.01 Kyoto, Japan

Tsubata, T.. Molecular and cellular aspects of antibody production and its abnormality. China Medical University 2008.11.27 Shenyang, China

Tsubata, T.. Cell death, autophagy, cell senescence and their roles in diseases. 7th Surugadai International Symposium 2008.11.16 Tokyo

Tsubata, T.. Endoplasmic reticulum stress and autoimmune diseases. Kongress der Deutschen Gesellschaft fur Rheumatologie 2008.09.24 Berlin, Germany

Tsubata, T.. Regulation of the B cell response by BCR and its co-receptors: Idling BCR engine model. Georg August University of Goettingen 2008.09.23 Goettingen, Germany

Tsubata, T.. Regulation of the B cell response by BCR and its co-receptors: Idling BCR engine model. Nikolaus Fiebiger Centre for Molecular Medicine, University of Erlangen-Nurnberg 2008.09.17 Erlangen, Germany,

Tsubata, T.. Regulation of the time course of B cell response by BCR and its co-receptors. Deutsches Rheuma-Forschungszentrum 2008.09.01 Berlin, Germany,

Tsubata, T.. Regulation of the B cell response by BCR and its co-receptors. MPI Immunobiology 2008.08.25 Freiburg, Germany,

Tsubata, T.. Functional role of inhibitory BCR co-receptors CD22 and CD72. 1st International Singapore symposium of immunology 2008.01.14 Singapore

Yu, J., Adachi, T., Gao, X., Takematsu, H., Tsubata, T. . 合成糖鎖リガンドによるＣＤ２２のＢ細胞受容体とのリピッドラフトでの共局在の阻害/ Synthetic glycan ligand excludes CD22 from antigen receptor-containing lipid rafts. . 第37回日本免疫学会総会・学術集会 2007.11.20 東京

Yan, B., Adachi, T., Tsubata, T.. 小胞体ストレスがＢ細胞抗原受容体を介したアポトーシスに関与する/ Unfolded protein response is involved in B cell antgen receptor-mediated apoptosis.. 第37回日本免疫学会総会・学術集会 2007.11.20 東京

Zhu, C., Adachi, T., Sato, M., Fujimoto, M., Tsubata, T. . An ITAM-like motif containing tyrosine 817 in CD22 together with an ITIM containing tyrosine 783 is sufficient for negative regulation of BCR signaling. . 第37回日本免疫学会総会・学術集会 2007.11.20 東京

Mohamed, A, A, H, H., Tsubata, T., Ishida, H. and Kiso, M. . Design and synthesis of novel sialosides as potential CD22-specific inhibitors. . XIX International Symposium on Glycoconjugates. (Glyco-19) 2007.07.15 Cairns, Australia.

A, A, H, H, Mohamed., Tsubata, T., Ishida, H. and Kiso, M.. Design and synthesis of novel sialosides as potential CD22-specific inhibitors. . The 2nd Annual meeting of Japanese society for chemical biology 2007.05.09 Kyoto

Yu, J. and Tsubata, T.. 糖鎖リガンド類似化合物によるBリンパ球活性化制御分子CD22の機能制御. 日本ケミカルバイオロジー研究会第２回年会 2007.05.09 京都

Tsubata, T.. Functional role of inhibitory BCR Co-receptors CD22 and CD72. . 1st International Singapore Symposium of Immunology. 2007.01.12 Biopolis, Singapore.

Zhu C, Sato M, Fujimoto M and Tsubata T. . The signal immunoreceptor tyrosine-based inhibition motif containing the tyrosine 783 in CD22 is sufficient for negative regulation of BCR signaling.. 第36回日本免疫学会総会学術集会 2006.12.11 大阪

Yu J, Adachi T, Gao X, Tsubata T.. Establishment of the screening for mouse CD22 inhibitors. . 第36回日本免疫学会総会学術集会 2006.12.11 大阪

厳斌成、安達貴弘、鍔田武志. B細胞抗原受容体を介したアポトーシスにおけるROSの役割. 第36回日本免疫学会総会学術集会 2006.12.11 大阪

Tsubata, T.. Immunoglobulin isotype-dependent regulation of B cell antigen receptor signaling mediated by Siglec2/CD22. . The 5th Sialoglycoscience 2006 International Conference 2006.08.27 Mishima

Toda M, Takeuchi N, Inoue M, Adachi T, Matsubara J, Taketani S, Tsubata T, Murata T and Nakada H.. Immunosuppressive effect of mucin on B cell function in tumor-bearing state. . 20th IUBMB International Congless of Biochemistry and Molecular Biology and 11th FAOBMB Congress. 2006.06.18 Kyoto

Zhu C, Tsubata T and Adachi T. . The single immunoreceptor tyrosine-based inhibition motif surrounding the tyrosine 783 in CD22 (siglec2) is sufficient for negative regulation of BCR signaling.. 20th IUBMB International Congless of Biochemistry and Molecular Biology and 11th FAOBMB Congress. 2006.06.18 Kyoto

厳斌成、安達貴弘、鍔田武志. B細胞抗原受容体を介したアポトーシスにおけるROSの解析. 日本ケミカルバイオロジー研究会第一回年会 2006.05.08 東京

于潔、澤田敏彦、安達貴弘、Xiaoming Gao, 石田秀治、木曾真、鍔田武志. マウスCD22阻害剤のスクリーニング系の構築. 日本ケミカルバイオロジー研究会第一回年会 2006.05.08 東京

Tsubata, T.. B cell tolerance and autoimmunity. . FIMSA/IIS Advanced Course on Immunology 2006.03.01 New Delhi, India

Adachi, T., Bin-Cheng Yan., Tsubata, T.. Screening of the genes related to the cell cycle arrest-induced apoptosis. . International Symposium on Life of Proteins 2005.10.30 Awajishi

Tsubata, T.. Cell cycle control of lymphocyte apoptosis. . Conference on “Cell Death, Cell Cycle and Cell Senescence” 2004.11.17 Kisarazu,

Tsubata, T.. Molecular switches regulating activation of naive and memory B lymphocytes. The Japan-China Cooperative Life Science Symposium in Kumamoto 2004.11.12 Kumamoto

Tsubata, T.. Molecular switches governing activation of naive and memory B lymphocytes.. National Center for AIDS/STD Control and Prevention (NCAIDS) 2004.09.22 Beijing

鍔田武志. Molecular switches determining activation vs. apoptosis of antigen-stimulated B lymphocytes. 理化学研究所和光本所 2004.09.02 和光市

Tsubata, T.. Isotype-specific regulation of B lymphocyte activation by siglec 2/CD22.. 21st International Lectin Meeting 2004.05.23 Shonan

Tsubata, T.. The level of c-Myc determines survival vs. apoptosis upon cell cycling.. UK-Japan Cell Cycle Workshop 2004.05.13 Nara

Tsubata, T.. From BCR signal regulation to better vaccination strategies. . China-Japan Planning Meeting for Cooperative Study on SARS 2004.02.21 Tokyo

Tsubata, T.. Immunoglobulin isotype-specific regulation of B cell antigen receptor signaling. Keystone Symposia 2004.01.08 Steamboat Springs

Adachi, T., Hokazono, Y., Matthias Wabl, Tsubata, T.. Inhibitory co-receptors activated by antigens but not by Anti-immunoglobulin heavy chain antibodies Install requirement of co-stimulation through CD40 for survival and proliferation of B cells. Keystone Symposia 2004 “Lymphocyte activation and signaling” 2004.01.08 Steamboat Springs

Tsubata, T.. Immunoglobulin isotype-specific regulation of B cell antigen receptor signaling.. Keystone Symposia 2004 “Lymphocyte activation and signaling” 2004.01.08 Steamboat Springs

Tsubata, T.. Regulation of antigen receptor signaling in B lymphocytes –Towards understanding of the molecular basis of vaccination-. . Symposium “From Genome Science to Medicine” 2003.11.29 東京

Tsubata, T.. Regulation of B lymphocyte activation by inhibitory BCR co-receptors CD22 and CD72. University of Bielefeld, 2003.11.11 Bielefeld

Tsubata, T.. Immunoglobulin isotype-specific regulation of B cell antigen receptor signaling. . Joint Meeting of STS and FZI 2003.11.06 Weimar

Tsubata, T.. Regulation of B lymphocyte activation by inhibitory BCR co-receptors CD22 and CD72. DRFZ 2003.11.04 Berlin

Tsubata, T.. CD40 signaling perturbs peripheral deletion of self-reactive B cells.. Workshop on the Genetics and Mechanisms of Autoimmunity, Princeton 2003.03.21 Princeton

饗場祐一、樋口哲也、西岡清、鍔田武志. CD40リガンドの異所性発現による末梢B細胞トレランス破綻機構の解析　. 第36回日本免疫学会総会 2002.12.04 東京

Y. Aiba, T. Higuch and T. Tsubata . Role of CD40 signaling in selection and maturation of B cells in vivo . 12th KTCC 2002.08.03 京都

Tsubata ,T.. CD40 signaling abrogates clonal deletion of dsDNA-reactive B cells and induces lupus-like autoimmune disease.. The 7th International Workshop on Autoantibodies and Autoimmunity. 2001.09.26 Awaji

Tsubata, T., Aiba, Y., Higuchi, T., Furukawa, k., Honjo, T.. CD40 signaling regulates selection of selfreactive B cells and maturation of gerninal center B cells in vivo. . 11th international congress of immunology. 2001.07.22 Stockholm,

Tsubata ,T.. Regulation of self-reactive B cells by CD40 signaling.. 17th DGfI spring meeting. 2001.01.21 Innsbruck

Tsubata, T.. Studies on B cell selection in CD40 ligand-transgenic mice.. South Florida University 2001.01.18 USA

Tsubata, T.. Studies on B cell selection in CD40 ligand-transgenic mice.. Duke University 2001.01.17 USA

Tsubata ,T., Higuchi,T., Aiba, Y., Honjo, T., and Martin Weigert. . Ectopic expression of CD40L on B cells abrogates self-tolerance and induces lupus-like autoimmune disease. . Keystone Symposia, Regulation of Immunity and Autoimminity. 2001.01.10 Keystone,

Aiba, Y., Higuchi, T., Takamori, T., Honjo,T., and Tsubata, T.. Transgenic expression of CD40 ligand promotes maturation of germinal center B cells in vibvo. Keystone Symposia. Regulation of Immunity and Autoimminity. 2001.01.10 Keystone,