Tamamura H.. New horizon of drug discovery for anti-HIV drugs. The 82nd FIP World Congress of Pharmacy and Pharmaceutical Sciences, HIV treatment: the future of preventative care and management 2024.09.01 Cape Town
Tamamura H.. Tripeptide-mimic Inhibitors against a Main Protease of SARS-CoV-2. The 18th Chinese International Peptide Symposium 2024.06.30 Hong Kong
山本 賢一, 小早川 拓也, 東 知佳, 渡邉 優基, 辻 耕平, 玉村 啓和. アミロイドbeta凝集阻害剤を指向したクロロアルケン型ペプチドミメティックの創製. 日本薬学会第144回年会 2024.03.31 横浜
篠原 功紀,鍬田 伸好,辻 耕平,石井 貴大,小早川 拓也,服部 真一朗,岸本 直樹,高宗 暢暁,三隅 将吾,Haydar Bulut,林 宏典,満屋 裕明,玉村 啓和. SARS-CoV-2メインプロテアーゼを標的とした高抗ウイルス活性を有する低分子阻害剤の創製. 日本薬学会第144回年会 2024.03.30 横浜
町田 沙穂, 小早川 拓也, 横山 勝, 藤野 真之, 金子 萌美, 倉上 真樹, 朴 清香, 大西 立人, 小谷 治, 辻 耕平, 村上 努, 佐藤 裕徳, 玉村 啓和. HIV-1カプシドタンパク質の構造を起点とした低分子型抗HIV-1剤の創製. 日本薬学会第144回年会 2024.03.30 横浜
黒田 悠貴, 小早川 拓也, 辻 耕平, 紺野 奇重, 大橋 南美, 増田 亜美, 三浦 裕太郎, 桑田 岳夫, 吉村 和久, 三浦 智行, 原田 恵嘉, 松下 修三, 玉村 啓和. HIV侵入阻害剤としてのポリエチレングリコールと低分子CD4ミミックのハイブリッド化合物の創製. 日本薬学会第144回年会 2024.03.30 横浜
西村 壮史, 小早川 拓也, 辻 耕平, 村上 努, 玉村 啓和. HIV-1外被タンパク質gp41を標的とする二価型膜融合阻害剤の創製. 日本薬学会第144回年会 2024.03.30 横浜
Tamamura H.. Medicinal chemistry derived from peptides and peptidomimetics. The 10th Joint Symposium between IBB/TMDU and Chulalongkorn University on Biomedical Materials and Engineering 2024.01.19 Thailand
Takuya Kobayakawa, Chika Azuma, Kenichi Yamamoto, Kohei Tsuji, Hirokazu Tamamura. Development of synthetic strategies for peptidomimetic based on a chloroalkene dipeptide isostere and its application to a cyclic peptide. The 15th International Kyoto Conference on New Aspects of Organic Chemistry 2023.11.21 Kyoto
Kohei Tsuji, Hirokazu Tamamura, Terrence R. Burke, Jr.. Utilization of a non-specific kinase inhibitor for the development of high-affinity bivalent polo-like kinase 1 polo-box domain inhibitors. The 60th Japanese Peptide Symposium 2023.11.10 Otsu
Takuya Kobayakawa, Chika Azuma, Kenichi Yamamoto, Kohei Tsuji, Hirokazu Tamamura. Development of convergent synthesis for peptidomimetic based on a chloroalkene dipeptide isostere and its application to a cyclic peptide. The 60th Japanese Peptide Symposium 2023.11.08 Otsu
Kouki Shinohara, Kohei Tsuji, Takahiro Ishii, Takuya Kobayakawa, Nobuyo Higashi-Kuwata, Yutaro Miura, Chika Azuma, Hironori Hayashi, Shin-ichiro Hattori, Haydar Bulut, Shogo Misumi, Hiroaki Mitsuya, Hirokazu Tamamura. Structure-activity relationship studies of novel SARS-CoV-2 main protease inhibitors with potent antiviral activity. The 60th Japanese Peptide Symposium 2023.11.08 Otsu
Hirokazu Tamamura. Anti-SARS-CoV-2 Agents Inspired from HIV Researches. The 13th International Peptide Symposium/The 15th Australian Peptide Conference 2023.10.17 Brisbane
Yutaro Miura, Rongyi Wang, Kohei Tsuji, Yishan Liu, Takuya Kobayakawa, Kazuhisa Yoshimura, Shuzo Matsushita, Shigeyoshi Harada, Hirokazu Tamamura. Combinational use of CD4 mimic with other anti-HIV agents and development of these hybrid molecules. 14th International Peptide Symposium 2023.10.17 Brisbane
Yutaro Miura, Rongyi Wang, Kohei Tsuji, Yishan Liu, Takuya Kobayakawa, Kazuhisa Yoshimura, Shuzo Matsushita, Shigeyoshi Harada, Hirokazu Tamamura. Double target inhibitors of HIV-1 entry based on hybrid molecules of CD4 mimics and HIV-1 gp41-related peptides. 26th Korean Peptide Protein Symposium 2023.07.04 Jeju
Takahiro Ishii, Kohei Tsuji, Takuya Kobayakawa, Nobuyo Higashi-Kuwata, Chika Azuma, Kouki Shinohara, Yutaro Miura, Hironori Hayashi, Haydar Bulut, Shogo Misumi, Hiroaki Mitsuya, Hirokazu Tamamura . Design and Synthesis of SARS-CoV-2 Mpro Inhibitors Containing Flurine Atoms and Amide Surrogates. 26th KPPS Annual Symposium 2023.07.03 Jeju
Hirokazu Tamamura. Anti-SARS-CoV-2 Agents Based on HIV Researches. The Seoul National University (SNU) seminar 2023.06.30 Korea
Hirokazu Tamamura. Development of potent and biostable inhibitors of the main protease of SARS-CoV-2 learned from HIV researches. The 14th AFMC International Medicinal Chemistry Symposium (AIMECS 2023) 2023.06.27 Korea
Takahiro Ishii, Takuya Kobayakawa, Kouki Matsuda, Kohei Tsuji, Nami Ohashi, Kazuhisa Yoshimura, Hiroaki Mitsuya, Kenji Maeda, Hirokazu Tamamura . Structure-Activity Relationship Studies of DAG-lactone Derivatives with HIV-1 Latancy Reversing Activity. 14th AFMC International Medicinal Chemistry Symposium 2023.06.27 Seoul
Yutaro Miura, Rongyi Wang, Kohei Tsuji, Yishan Liu, Takuya Kobayakawa, Kazuhisa Yoshimura, Shuzo Matsushita, Shigeyoshi Harada, Hirokazu Tamamura. Hybrid molecules of CD4 mimic and HIV-1 fusion inhibitors. 14th AFMC International Medicinal Chemistry Symposium 2023.06.26 Seoul
Hirokazu Tamamura. Peptidomimetic-based Anti-SARS-CoV-2 Agents Learned from Anti-HIV Agents. The 17th Chinese International Peptide Symposium 2023.06.14 China
Hirokazu Tamamura. Development of Anti-SARS-CoV-2 Agents Learned from Anti-HIV Agents. The 19th Akabori Conference 2023: German-Japanese Symposium on Peptide Science 2023.05.19 Otsu
Hirokazu Tamamura. Use of synthetic peptides in infectious diseases research; vaccines, therapeutics and diagnostics. Discovery Research Platforms 2023.03.23 Online
Hirokazu Tamamura. Peptide-lead medicinal chemistry: from AIDS to COVID-19. The 9th Joint Symposium between IBB/TMDU and Chulalongkorn University on Biomedical Materials and Engineering 2023.01.23 Thailand
Kofi Baffour-Awuah Owusu , Kohei Tsuji , Takuya Kobayakawa , Youichi Suzuki, Hirokazu Tamamura. Development of SARS-CoV-2 Fusion Inhibitor Peptides Based on SARS-CoV-2 HR-2. The 39th Medicinal Chemistry Symposium 2022.11.23 Online
Yutaro Miura, Takuya Kobayakawa, Kohei Tsuji, Kiju Konno, Ami Masuda, Nami Ohashi, Takeo Kuwata, Kazuhisa Yoshimura, Tomoyuki Miura, Shigeyoshi Harada, Shuzo Matsushita, Hirokazu Tamamura. Pegylated CD4 mimics as HIV inhibitors. The 59th Japanese Peptide Symposium 2022.10.26 Sendai
Takahiro Ishii, Kohei Tsuji, Takuya Kobayakawa, Nobuyo Higashi-Kuwata, Chika Azuma, Miyuki Nakayama, Kouki Shinohara, Yutaro Miura, Hironori Hayashi, Shin-ichiro Hattori, Haydar Bulut, Shogo Misumi, Hiroaki Mitsuya, Hirokazu Tamamura. Synthesis of inhibitors targeting the main protease of SARS-CoV-2 for therapeutics of COVID-19. The 59th Japanese Peptide Symposium 2022.10.26 Sendai
Kohei Tsuji, Kofi Baffour-Awuah Owusu, Takuya Kobayakawa, Youichi Suzuki, Hirokazu Tamamura. Development of fusion inhibitor peptides of SARS-CoV-2 learned from anti-HIV-1 agents. The 59th Japanese Peptide Symposium 2022.10.26 Sendai
Kouki Shinohara, Kohei Tsuji, Takahiro Ishii, Takuya Kobayakawa, Nobuyo Higashi-Kuwata, Yutaro Miura, Hironori Hayashi, Shin-ichiro Hattori, Haydar Bulut, Shogo Misumi, Hiroaki Mitsuya, Hirokazu Tamamura. Structure-activity relationship studies of SARS-CoV-2 main protease inhibitors. The 59th Japanese Peptide Symposium 2022.10.26 Sendai
Kohei Tsuji, Rongyi Wang, Kofi Baffour-Awuah Owusu, Takuya Kobayakawa, Tsutomu Murakami, Hirokazu Tamamura. Exploration of novel class anti-HIV-1 agents derived from a viral capsid protein. 36th European and 12th International Peptide Symposium 2022.08.29 Spain
Hirokazu Tamamura . From HIV to SARS-CoV-2: Fusion Inhibitors Based on Dimerization of HR2 Region Peptides. Frontiers in Peptide Science and Drug Discovery: A Scientific Symposium in Honor of Professor James P. Tam 2022.08.05 Singapore
Hirokazu Tamamura. Medicinal chemistry based on peptidomimetics. The 8th Joint Symposium between Chulalongkorn University and IBB/TMDU on Biomedical Materials and Engineering 2022.01.25 Online
Hirokazu Tamamura. Bivalent Ligands of GPCR as Molecular Measures, Bioprobes for Cancer Cells and Anti-cancer Agents. The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021) 2021.12.20 Online
Hirokazu Tamamura, Takuya Kobayakawa, Kento Ebihara, Tsutomu Murakami, Kohei Tsuji. Development of HIV-1 fusion inhibitors based on dimeric derivatives of the C34 peptide and its peptidomimetics. The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021) 2021.12.18 Online
Takahiro Ishii, Takuya Kobayakawa, Kouki Matsuda, Kohei Tsuji, Kazuhisa Yoshimura, Hiroaki Mitsuya, Kenji Maeda, Hirokazu Tamamura. Development of protein kinase C activators for cure of HIV infectious diseases. The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021) 2021.12.15 Online
Kohei Tsuji, Rongyi Wang, Kofi Baffour-Awuah Owusu, Takuya Kobayakawa, Tsutomu Murakami, Hirokazu Tamamura. Explorative study in development of anti-HIV-1 peptides based on HIV-1 capsid protein segments. The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021) 2021.12.15 Online
Takuya Kobayakawa, Kohei Tsuji, Kiju Konno, Ami Masuda, Nami Ohashi, Takeo Kuwata, Kazuhisa Yoshimura, Tomoyuki Miura, Shigeyoshi Harada, Shuzo Matsushita, Hirokazu Tamamura. HIV entry inhibitors based on CD4 mimics with PEG units toward cure for HIV-infectious diseases. The 13th AFMC International Medicinal Chemistry Symposium 2021.12.02 Online
Takahiro Ishii, Takuya Kobayakawa, Kouki Matsuda, Kohei Tsuji, Kazuhisa Yoshimura, Hiroaki Mitsuya, Kenji Maeda, Hirokazu Tamamura. Structure-Activity Relationship Studies of Protein Kinase C Activators Derived from Diacylglycerol for Cure of HIV Infectious Diseases. The 13th AFMC International Medicinal Chemistry Symposium 2021.11.29 Online
Rongyi Wang, Kohei Tsuji, Yishan Liu, Takuya Kobayakawa, Tsutomu Murakami, Hirokazu Tamamura. HYBRID MOLECULES OF CD4 MIMIC AND HIV-1 GP41-RELATED PEPTIDES AS FUSION INHIBITORS. 第58回ペプチド討論会 2021.10.22 online(Tokyo)
Rongyi Wang, Kohei Tsuji, Yishan Liu, Takuya Kobayakawa, Tsutomu Murakami, Hirokazu Tamamura. HYBRID MOLECULES OF CD4 MIMIC AND HIV-1 GP41-RELATED PEPTIDES AS FUSION INHIBITORS. The 58th Japanese Peptide Symposium 2021.10.22 Online
Kohei Tsuji, Takuya Kobayakawa, Kento Ebihara, Takuma Kawada, Masayuki Fujino, Yuzuna Honda, Nami Ohashi, Tsutomu Murakami, Hirokazu Tamamura. DIMERIZED SMALL MOLECULE HIV-1 FUSION INHIBITORS WITH DRAMATIC ENHANCEMENT OF THEIR ANTI-HIV-1 ACTIVITIES. The 58th Japanese Peptide Symposium 2021.10.21 Online
Kohei Tsuji, Takahiro Ishii, Takuya Kobayakawa, Nami Ohashi, Wataru Nomura, Hirokazu Tamamura. A FRET-BASED ASSAY SYSTEM FOR PROTEIN KINASE C LIGAND SCREENING USING 1,2-DIACYLGLYCEROL-LACTONE DERIVATIVE. The 58th Japanese Peptide Symposium 2021.10.20 Online
Hirokazu Tamamura. Development of Anti-HIV and Anti-cancer Peptides. The 18th Akabori Conference: Japanese-German Symposium on Peptide Science 2021.03.08 Online
Kohei Tsuji. Kinase inhibitors for anti-cancer drugs. The 7th Joint Symposium between Chulalongkorn University and IBB/TMDU on Biomedical Materials and Engineering 2020.12.22 online (Thailand)
Hirokazu Tamamura. Mid-size drugs based on peptidomimetics. The 7th Joint Symposium between Chulalongkorn University and IBB/TMDU on Biomedical Materials and Engineering 2020.12.22 online (Thailand)
Hirokazu Tamamura. Bioimaging of GPCR dimers and its application to molecular probes for cancer cells. A3 Foresight & 5 Star Alliance Joint Workshop on Organic/Inorganic Hybrid Nano Materials and Bio Imaging 2020.12.03 online
Kaho Matsumoto, Takeo Kuwata, Zahid Hasan, Yu Kaku, Shashwata Biswas, Shokichi Takahama, Hirokazu Tamamura and Shuzo Matsushita. The CD4 mimetic compound YIR-821-mediated enhancement of the neutralization activities of plasma IgG against autologous isolates in vitro.. 21st Kumamoto AIDS Seminar 2020.11.11 online(Kumamoto)
Kohei Tsuji, David Hyme, Buyong Ma, Ruth Nussinov, Hirokazu Tamamura,Terrence R. Burke, Jr.. Development of bivalent inhibitors of polo-like kinase 1 with great affinity enhancement. The 57th Japanese Peptide Symposium 2020.11.10 online (Tottori)
Wataru Nomura, Takumi Kamimura, Takuya Kobayakawa, Hirokazu Tamamura. Endogenous protein expression imaging by fluorogenic ZIP tag-probe system. The 57th Japanese Peptide Symposium 2020.11.10 online (Tottori)
Kofi Baffour-Awuah Owusu, Kohei Tsuji, Rongyi Wang, Takuya Kobayakawa, Moemi Kaneko, Tsutomu Murakami, Hirokazu Tamamura. Exploratory studies on the development of anti-HIV-1 peptides based on HIV-1 capsid fragments. The 57th Japanese Peptide Symposium 2020.11.10 online(Tottori)
Chika Azuma, Takuya Kobayakawa, Kohei Tsuji, Hirokazu Tamamura. A convergent synthesis of chloroalkene dipeptide isosteres as peptidomimetics. The 57th Japanese Peptide Symposium 2020.11.09 online (Tottori)
Hirokazu Tamamura. Bivalent HIV-1 fusion inhibitors using peptidomimetics. 16th Chinese International Peptide Symposium 2020.09.25 online/Hefei, China (Keynote Speaker)
Hirokazu Tamamura . Bivalent Ligands of GPCR as Molecular Measures, Bioprobes for Cancer Cells and Anti-cancer Agents. The 7th SNU Symposium on Medicinal Chemistry 2020.02.14 Seoul, Korea
Hirokazu Tamamura . Peptide-lead medicinal chemistry: anti-cancer & HIV agents. The 6th Joint Symposium between Chulalongkorn University and IBB/TMDU on Biomedical Materials and Engineering 2020.01.14 Bangkok, Thailand
Maeda Kenji, Matsuda Kouki, Islam Saiful, Kobayakawa Takuya, Tsuchiya Kiyoto, Hattori Shin-ichiro, Gatanaga Hiroyuki, Oka Shinichi, Yoshimura Kazuhisa, Tamamura Hirokazu, Mitsuya Hiroaki, Satou Yorifumi. HIV持続潜伏感染に関する最先端研究 HIV治癒に向けたlatency reversing agents(LRAs)を用いたHIV-1リザーバーの治療(Treatment of HIV-1-reservoirs using latency-reversing agents(LRAs) toward HIV cure). 日本エイズ学会誌 2019.11.01
Maeda Kenji, Matsuda Kouki, Islam Saiful, Kobayakawa Takuya, Tsuchiya Kiyoto, Hattori Shin-ichiro, Gatanaga Hiroyuki, Oka Shinichi, Yoshimura Kazuhisa, Tamamura Hirokazu, Mitsuya Hiroaki, Satou Yorifumi. HIV持続潜伏感染に関する最先端研究 HIV治癒に向けたlatency reversing agents(LRAs)を用いたHIV-1リザーバーの治療(Treatment of HIV-1-reservoirs using latency-reversing agents(LRAs) toward HIV cure). 日本エイズ学会誌 2019.11.01
Maeda Kenji, Matsuda Kouki, Islam Saiful, Kobayakawa Takuya, Tsuchiya Kiyoto, Hattori Shin-ichiro, Gatanaga Hiroyuki, Oka Shinichi, Yoshimura Kazuhisa, Tamamura Hirokazu, Mitsuya Hiroaki, Satou Yorifumi. HIV持続潜伏感染に関する最先端研究 HIV治癒に向けたlatency reversing agents(LRAs)を用いたHIV-1リザーバーの治療(Treatment of HIV-1-reservoirs using latency-reversing agents(LRAs) toward HIV cure). 日本エイズ学会誌 2019.11.01
Maeda Kenji, Matsuda Kouki, Islam Saiful, Kobayakawa Takuya, Tsuchiya Kiyoto, Hattori Shin-ichiro, Gatanaga Hiroyuki, Oka Shinichi, Yoshimura Kazuhisa, Tamamura Hirokazu, Mitsuya Hiroaki, Satou Yorifumi. HIV持続潜伏感染に関する最先端研究 HIV治癒に向けたlatency reversing agents(LRAs)を用いたHIV-1リザーバーの治療(Treatment of HIV-1-reservoirs using latency-reversing agents(LRAs) toward HIV cure). 日本エイズ学会誌 2019.11.01
Maeda Kenji, Matsuda Kouki, Islam Saiful, Kobayakawa Takuya, Tsuchiya Kiyoto, Hattori Shin-ichiro, Gatanaga Hiroyuki, Oka Shinichi, Yoshimura Kazuhisa, Tamamura Hirokazu, Mitsuya Hiroaki, Satou Yorifumi. HIV持続潜伏感染に関する最先端研究 HIV治癒に向けたlatency reversing agents(LRAs)を用いたHIV-1リザーバーの治療(Treatment of HIV-1-reservoirs using latency-reversing agents(LRAs) toward HIV cure). 日本エイズ学会誌 2019.11.01
Tsutomu Murakami, Kento Ebihara, Takuya Kobayakawa, Masayuki Fujino, Eiichi Kodama, Hirokazu Tamamura. Elucidation of mechanism of HIV-1 fusion inhibitors developed by dimerization strategy. The 67th Annual Meeting of the Japanese Society for Virology 2019.10.29 Tokyo
Kouki Matsuda, Takuya Kobayakawa, Kiyoto Tsuchiya, Shin-ichiro Hattori, Hiroyuki Gatanaga, Kazuhisa Yoshimura, Shinichi Oka, Yasuyuki Endo, Hirokazu Tamamura, Hiroaki Mitsuya, Kenji Maeda. Benzolactam protein kinase C activators promote apoptosis of HIV-infected human cells via HIV latency reversal. The 67th Annual Meeting of the Japanese Society for Virology 2019.10.29 Tokyo
Wataru Nomura, Takumi Kamimura, Takuya Kobayakawa, Hirokazu Tamamura. Fluorogenic ZIP tag-probe system for fluorescent imaging of endogenous protein expression. The 56th Japanese Peptide Symposium 2019.10.25 Tokyo
Rongyi Wang, Takuya Kobayakawa, Moemi Kaneko, Kofi Owusu, Tsutomu Murakami, Hirokazu Tamamura. Development of cell-permeable anti-HIV peptides based on capsid proteins. The 56th Japanese Peptide Symposium 2019.10.25 Tokyo
Maxwell M. Sakyiamah, Wataru Nomura, Takuya Kobayakawa, Hirokazu Tamamura. Development of a nanoBRET-based sensitive screening method to search for chemokine receptor CXCR4 ligands. The 56th Japanese Peptide Symposium 2019.10.25 Tokyo
Kento Ebihara, Yuzuna Honda, Takuya Kobayakawa, Tsutomu Murakami, Hirokazu Tamamura. Development of HIV-1 fusion inhibitors based on the C34 dimer derived from an HIV-1 envelope protein gp41. The 56th Japanese Peptide Symposium 2019.10.23 Tokyo
Yuki Watanabe, Takuya Kobayakawa, Atsuhiko Taniguchi, Yoshio Hayashi, Hirokazu Tamamura. Development of peptidomimetic inhibitors for aggregation of amyloid beta. The 56th Japanese Peptide Symposium 2019.10.23 Tokyo
Takuya Kobayakawa, Hirokazu Tamamura. Development of chemical synthesis for peptidomimetic based on a chloroalkene dipeptide isostere and its application to a cyclic peptide. The 56th Japanese Peptide Symposium 2019.10.23 Tokyo
Masaki Kurakami, Takuya Kobayakawa, Masaru Yokoyama, Tsutomu Murakami, Moemi Kaneko, Osamu Kotani, Hironori Sato, Hirokazu Tamamura. Structure-activity relationship studies of small molecular anti-HIV-1 compounds targeting a dipeptide site of HIV-1 capsid proteins. The 56th Japanese Peptide Symposium 2019.10.23 Tokyo
Hirokazu Tamamura. Elucidation of a dimerization state of a GPCR and its application to molecular probes for cancer cells. The 2019 International Conference on Molecular Imaging and Minimally Invasive Therapy (2019 MIMIT) 2019.10.18 Beijing, China
Hirokazu Tamamura. Development of bivalent ligands of GPCR and their application to molecular probes for cancer cells and anti-cancer agents. 7th Modern Solid Phase Synthesis & Its Applications Symposium 2019.09.07 Palm Cove, Australia
Tamamura H. Peptide drug discovery. 25th Peptide Forum – International Forum on Peptides in Drug Discovery - /Satellite Symposium of 10th International Peptide Symposium 2018.12.10 Tokyo, Japan
Wataru Nomura , Takumi Kamimura, Daisuke Matsumoto, Takuya Kobayakawa, Hirokazu Tamamura. Fluorogenic and genetically encodable tag-probe system for in-cell imaging of protein synthesis . 10th International Peptide Symposium 2018.12.05 Kyoto, Japan
Tamamura H. Peptidomimetic-based mid-size drugs: anti-cancer and anti-HIV agents. 10th International Peptide Symposium/55th Japanese Peptide Symposium 2018.12.03 Kyoto, Japan
Takuya Kobayakawa, Hirokazu Tamamura. Synthetic Strategy of Peptidomimetic Based on Chloroalkene Dipeptide Isoteres and Its Biological Application. 10th International Peptide Symposium 2018.12.03 Kyoto, Japan
Kento Ebihara, Yuzuna Honda, Takuya Kobayakawa, Tsutomu Murakami, Hirokazu Tamamura. HIV-1 Fusion Inhibitors Based on gp41-C34 dimers. 10th International Peptide Symposium 2018.12.03 Kyoto, Japan
Takuya Kobayakawa, Kohei Takahashi, Ami Masuda, Shigeyoshi Harada, Tomoyuki Miura, Shuzo Matsushita, Kazuhisa Yoshimura, Hirokazu Tamamura. Structure‐activity relationship studies of CD4 mimic molecules for targeting an envelope protein gp120 on HIV-1. 19th Kumamoto AIDS Seminar 2018.11.06 Kumamoto, Japan
Takuya Kobayakawa, Kohei Takahashi, Ami Masuda, Shigeyoshi Harada, Tomoyuki Miura, Shuzo Matsushita, Kazuhisa Yoshimura, Hirokazu Tamamura. Structure‐activity relationship studies of CD4 mimic molecules for targeting an envelope protein gp120 on HIV-1. 19th Kumamoto AIDS Seminar 2018.11.06 Kumamoto, Japan
Tsutomu Murakami, Kento Ebihara, Masayuki Fujino, Yuzuna Honda, Takuya Kobayakawa, Wataru Nomura, Hirokazu Tamamura. Development of new membrane fusion inhibitors against HIV-1 by “dimerization” strategy. The 66th Annual Meeting of the Japanese Society for Virology 2018.10.28 Kyoto, Japan
Daisuke Matsumoto, Wataru Nomura, Hirokazu Tamamura. Split site-specific nucleases for controlled genome editing by chemicals. Frontiers 2018 Symposium (EPFL/TMDU/UTokyo Joint Symposium) 2018.09.21 Lausanne, Switzerland
Tamamura H. Peptidomimetic-based mid-size drugs: anti-cancer and anti-HIV agents. Frontiers 2018 Symposium (EPFL/TMDU/UTokyo Joint Symposium) 2018.09.21 Lausanne,Switzerland
Maxwell M. Sakyiamah, Wataru Nomura, Takuya Kobayakawa, Hirokazu Tamamura. Development of a new NanoBRET assay system for CXCR4 ligands and their Structure-activity relationship studies. Frontiers 2018 Symposium (EPFL/TMDU/UTokyo Joint Symposium) 2018.09.21 Lausanne, Switzerland
Maxwell Mamfe Sakyiamah, Wataru Nomura, Takuya Kobayakawa, Hirokazu Tamamura. Development of NanoBRET assay system in living cells for structure-activity relationship studies of CXCR4 ligands. The 62nd Annual Meeting of the Pharmaceutical Society of Japan Kanto Branch 2018.09.15 Tokyo, Japan
Tamamura H. Synthesis of Peptidomimetics Based on Chloroalkene Dipeptide Isosteres and Their Biological Application. The 17th Akabori Conference 2018: German- Japanese Symposium on Peptide Science 2018.09.04 Lindau,Germany
小早川 拓也. “化学”から“薬”の開発へ. 2018年度 国立大学法人 東京医科歯科大学 オープンキャンパス サイエンスカフェ(最新医歯学研究)~研究者の話を聞こう~ 2018.07.27 東京, 日本
Tamamura H. HIV-1 fusion inhibitors based on the C34 dimers derived from gp41. 15th Chinese International Peptide Symposium 2018.07.04 Shenzhen,China
Maxwell M. Sakyiamah, Wataru Nomura, Takuya Kobayakawa, Hirokazu Tamamura. Development of NanoBRET assay system in living cells to search potent CXCR4 ligands. The 13th Annual Meeting of Japanese Society for Chemical Biology 2018.06.13 Tokyo, Japan
Tsutomu Murakami, Masayuki Fujino, Masaru Yokoyama, Takuya Kobayakawa, Hiroaki Takeuchi, Takao Masuda, Osamu Kotani, Hirokazu Tamamura, Hironori Sato. Biological and molecular characterization of a novel anti-HIV-1 compound created by in silico design and de novo organic synthesis. Cold Spring Harbor Laboratory Meetings & Courses, Retrovirus Meeting 2018.05.23 Cold Spring Harbor, United States of America
Maxwell M. Sakyiamah, Wataru Nomura, Hirokazu Tamamura. Development of a sensitive screening method to search potent ligands of CXCR4. 138th Annual Meeting of the Pharmaceutical Society of Japan 2018.03.26 Ishikawa, Japan
Wataru Nomura, Daisuke Matsumoto, Taisuke Sugii, Takuya Kobayakawa, Hirokazu Tamamura. Differential regulation of endogenous genes in an orthogonal manner by distinct chemically inducible systems. International Conference on Epigenetics and Bioengineering 2017.12.13 Miami, United States of America
Tamamura H. Synthesis of chloroalkene dipeptide isosteres as peptidomimetics and their biological application. 12th Australian Peptide Conference 2017 2017.10.17 Noosa, Australia
Toyama K, Nomura W, Tamamura T. Functional evaluation of intracellular delivery peptides based on the EGF receptor dimerization arm sequences. 12th Australian Peptide Conference 2017 2017.10.16 Noosa, Australia
Nomura W, Matsumoto D, Hashimoto T, Sugii T, Tamamura H. Development of chemical-inducible artificial transcription factors based on sequence-specific DNA binders. the 254th ACS National Meeting and Exposition 2017.08.20 Washington DC, USA
Ohashi N, Harada S, Irahara Y, Ishida Y, Konno K, Kobayakawa T, Nomura W, Matsushita S, Yoshimura K, Tamamura H. CD4 Mimics for Enhancement of Activity of HIV Neutralizing Antibodies. The 11th AFMC International Medicinal Chemistry Symposium 2017.07.24 Melbourne, Australia
Tamamura H. Rigid bivalent ligands of the chemokine receptor CXCR4 and their anti-cancer metastasis activity. KCS Biochemistry Division Summer Workshop 2017.06.27 Jeju, Korea
Ebihara K, Honda Y, Nomura W, Murakami T, Tamamura H. Development of HIV-1 fusion inhibitors based on the C34 dimers derived from gp41. The 21st Korean Peptide Protein Society Symposium 2017.06.25 Jeju, Korea
Nomura W, Tanaka T, Aoki T, Tamamura H. Bivalent Ligands of the Chemokine Receptor CXCR4 with Polyproline Linkers and Their Anti-chemotactic Activity. The 25th American Peptide Symposium and the 9th International Peptide Symposium 2017.06.21 Whistler, Canada
Takuya Kobayakawa, Hirokazu Tamamura. Development of Synthetic Methods for Chloroalkene Dipeptide Isosteres and Their Applications. The 25th American Peptide Symposium and the 9th International Peptide Symposium 2017.06.19 Whistler, Canada
Nomura W, Sugii T, Tamamura H. Chemical-inducible artificial transcription factors based on sequence-specificity of TALE and dCas9. Keystone Symposia Precision Genome Engineering 2017.01.08 Breckenridge, USA
HashimotoT, Nomura W, Ohura I, Tamamura H. Improved split DNA methylase activity by optimization of assembly on target sites. Keystone Symposia Precision Genome Engineering 2017.01.08 Breckenridge, USA
Matsumoto D, Nomura W, Tamamura H. Controllable genome editing by chemically inducible split site-specific nucleases. Keystone Symposia Precision Genome Engineering 2017.01.08 Breckenridge, USA
Tamamura H. Medicinal Chemistry/Peptide & Protein Chemistry/Chemical Biology- Peptidomimetic-based Mid-Size Drugs –. The 3rd Joint Symposium between Chulalongkorn University and IBB/TMDU on Biomedical Materials and Engineering, Chulalongkorn University 2016.12.15 Bangkok, Thailand
Nomura W, Tamamura H. Design of synthetic peptides mimicking dynamic supramolecular mechanisms in HIV fusion as antigens and inhibitors against trimer-form of gp41. Antibody Engineering & Therapeutics 2016.12.12 San Diego, California
Tamamura H. Mid-size Drugs: Peptide-lead Anti-HIV Agents. The 2nd Peptides and Proteins Symposium Singapore 2016.12.09 Singapore, Singapore
Takuya Kobayakawa, Yudai Matsuzaki, Wataru Nomura, Kentaro Hozumi, Motoyoshi Nomizu, Hirokazu Tamamura. Development of Chloroalkene Dipeptide Isosteres as Peptidomimetics and Their Application. The 2nd Peptides and Proteins Society of Singapore Symposium 2016.12.08 Nanyang Technological University, Singapore
Tamamura H. Mid-sized drugs based on peptide mimetics. 15th Surugadai International Symposium 2016.11.29 Tokyo, Japan
Takano H, Nomura W, Tamamura H. Development of a Hydrophilic Caged PKC Ligand with an 8-Azacoumarin Photolabile Protecting Group for the Precise Photocontrol of PKC Activation. 34th European Peptide Symposium 2016 & 8th International Peptide Symposium 2016.09.08 Leipzig, Germany
Toyama K, Mizuguchi T, Nomura W, Tamamura H. Functional Evaluation of Fluorescein-Labeled Peptides Based on the EGF Receptor Dimerization Arm Sequences. 34th European Peptide Symposium 2016 & 8th International Peptide Symposium 2016.09.08 Leipzig, Germany
Tamamura H. Mid-Size Drugs: Dimer& Trimer Mimics of HIV-gp41 Peptides as Fusion Inhibitors. 34th European Peptide Symposium 2016 & 8th International Peptide Symposium 2016.09.05 Leipzig, Germany
Takuya Kobayakawa, Hirokazu Tamamura. Development of synthetic methodology of chloroalkene-type dipeptide isosteres for peptidomimetics. 252nd American Chemical Society National Meeting 2016.08.23 Pennsylvania, United States of America
Nomura W, Ohashi N, Tamamura H. Protein Dynamics Imaging Using Tag-probe Systems. The 14th Chinese International Peptide Symposium & the 5th Asia-Pacific International Peptide Symposium 2016.07.06 Nanjing, China
Miyaki D, Mizuguchi T, Nomura T, Takahashi D, Tamamura H. Synthesis of Anti-Integrase Stapled Peptides with a Soluble Linker. The 14th Chinese International Peptide Symposium & the 5th Asia-Pacific International Peptide Symposium 2016.07.06 Nanjing, China
Toyama K, Mizuguchi T, Nomura W, and Tamamura H. Development of New Fluorescein-Labeled Peptides with Inhibitory Effect on the EGF Receptor Activation. The 20th Korean Peptide Protein Society Symposium 2016.06.24 Yangyang, Korea
Tamamura H. Mid-Size Drugs: HIV Fusion Inhibitors Based on the C34 Dimer/Trimer Derived from gp41. The 20th Korean Peptide Protein Society Symposium 2016.06.24 Yangyang, Korea
Nomura W, Sugii T, Tamamura H. Chemically-inducible gene regulation system utilizing sequence-specificity of TALE and dCas9. FASEB SRC: Genome Engineering: Cutting-Edge Research and Applications 2016.06.08 Lisbon、Portugal
Nomura W, Ohashi N, Tamamura H. Tag-probe Systems for Protein Dynamics Imaging. The 16th Akabori Conference: Japanese-German Symposium on Peptide Science 2016.05.24 Kobe, Japan
Tetsuo Narumi, Takuya Kobayakawa, Hirokazu Tamamura. Highly Diastereoselective Synthesis of (Z)-Chloroalkene Dipeptide Isosteres by Remote Stereoinduction in the Organocuprate-Mediated Allylic Alkylation of Allylic gem-Dichlorides. Molecular Chirality Asia 2016 2016.04.20 Osaka, Japan
Nomura W, Ohashi N, Tamamura H. In-cell fluorogenic tag-probe system for protein localization and dynamics imaging. 251st American Chemical Society National Meeting 2016.03.17 San Diego, USA
Takano H, Narumi T, Nomura W, Furuta T, Tamamura H. Development of water-soluble and highly photosensitive 8-azacoumarin-4-ylmethyl-type photolabile-protecting groups for dynamic analysis of bioactive molecules. 251st American Chemical Society National Meeting 2016.03.16 San Diego, USA
Takuya Kobayakawa, Hirokazu Tamamura. Development of Chloroalkene Dipeptide Isosteres as Peptidomimetic Based on the Ground State of Peptide Bonds. 第8回武田科学振興財団薬科学シンポジウム 生命分子から薬を創る -中分子薬を中心に- 2016.01.26 大阪, 日本
Nomura W, Masuda A, Tamamura H. Efficient conversion of genomic promoter region by genome engineering systems. Pacifichem 2015 2015.12.15 Honolulu, USA
Tamamura H. Multivalent ligands for CXCR4 with polyproline linkers showing specific recognition for its expression. The 7th International Peptide Symposium 2015.12.11 Singapore, Singapore
Takuya Kobayakawa, Hirokazu Tamamura. Development of Synthetic Methods for Chloroalkene Dipeptide Isosteres as Peptidomimetic Based on the Ground State of Amide Bonds. The 7th International Peptide Symposium 2015.12.09 Matrix Biopolis, Singapore
Tamamura H. Multivalent ligands showing specific recognition for CXCR4 expression. The Seventh Peptide Engineering Meeting (PEM7) 2015.12.07 Pune, India
本田柚子奈, 野村 渉, 藤野真之, 村上 努, 玉村啓和. HIV外被タンパク質gp41の断片ペプチドC34を基にした二量化膜融合阻害剤の創製. 第29回日本エイズ学会学術集会・総会 2015.11.30 東京
宮木大輔, 水口貴章, 村上 努, 野村 渉, 玉村啓和. HIV-1遺伝子産物ペプチドを基とするインテグラーゼ阻害剤の構造活性相関研究. 第29回日本エイズ学会学術集会・総会 2015.11.30 東京
谷田部夏香, 松本大地, 橋本知恵, 藤野真之, 水口貴章, 大橋南美, 野村 渉, 村上 努, 玉村啓和. HIV-1カプシドタンパク質由来ペプチドライブラリーの構築と阻害剤の創出. 第29回日本エイズ学会学術集会・総会 2015.11.30
Misato Kotani, Yu Irahara, Yusuke Ishida, Shigeyoshi Harada, Nami Ohashi, Yuko Yamada, Takaaki Mizuguchi, Tomoyuki Miura, Wataru Nomura, Shuzo Matsushita, Kazuhisa Yoshimura, Hirokazu Tamamura. Development of small CD4 mimic molecules with a mono-cyclohexyl type group targeting HIV-1 gp120. 第29回日本エイズ学会学術集会・総会 2015.11.30 東京
石田有佑, 水口貴章, 原田恵嘉, 三浦智行, 小谷みさと, 山田裕子, 苛原 優, 野村 渉, 松下修三, 吉村和久, 玉村啓和. 新規CD4ミミックの創製と薬物動態解析. 第29回日本エイズ学会学術集会・総会 2015.11.30 東京
水口貴章, 苛原 優, 原田恵嘉, 三浦智行, 小谷みさと, 石田有佑, 山田裕子, 大橋南美, 野村 渉, 松下修三, 吉村和久, 玉村啓和. 薬物動態の改善を志向した低分子CD4ミミックの創製研究. 第29回日本エイズ学会学術集会・総会 2015.11.30 東京
水口貴章, 外山 桂, 石田有佑, 野村 渉, 玉村啓和. 上皮成長因子受容体の「二量体化アーム」を基盤とした新規抗がん薬開発に向けた環状ペプチドに関する研究. 第33回メディシナルケミストリーシンポジウム 2015.11.26 幕張
石田有佑, 水口貴章, 原田恵嘉, 三浦智行, 小谷みさと, 山田裕子, 苛原 優, 野村 渉, 松下修三, 吉村和久, 玉村啓和. カテコール誘導体を基盤とした新規CD4ミミックの創製と薬物動態解析. 第33回メディシナルケミストリーシンポジウム 2015.11.26 幕張
Yuzuna Honda, Masayuki Fujino, Wataru Nomura, Hirokazu Tamamura, Tsutomu Murakami. Dimerization of C34 Derivatives with C-Terminal Disulfide Bridge and Addition of an N-Terminal GCGG Markedly Enhance anti-HIV-1 Activity. 第63回日本ウイルス学会学術集会 2015.11.22 福岡
Nomura W, Masuda A, Tamamura H. Simultaneous digestion by site-specific nucleases for efficient gene deletion: Study of hTERT promoter function. Conference on Transposition and Genome Engineering 2015 2015.11.17 Nara. Japan
Nami Ohashi, Wataru Nomura, Natsuki Minato, Hirokazu Tamamura. FRET-Based Binding Assay for PKC Ligands with Small Fluorescent Dyes. 第52回ペプチド討論会 2015.11.16
Takaaki Mizuguchi, Kei Toyama, Yusuke Ishida, Wataru Nomura, Hirokazu Tamamura. Functional Evaluation of Fluorescent-Labeled Derivatives of an Inhibitory Peptide against EGF Receptor Dimerization. 第52回ペプチド討論会 2015.11.16
Kei Toyama, Takaaki Mizuguchi, Yusuke Ishida, Wataru Nomura, Hirokazu Tamamura. Studies on a Novel Delivery Peptide Derived from the Dimerization Arm of EGF Receptor. 第52回ペプチド討論会 2015.11.16 平塚
Hikaru Takano, Tetsuo Narumi, Wataru Nomura, Toshiaki Furuta, Hirokazu Tamamura. Improvement of Photolytic Efficiency of the 8-Azacoumarin Chromophore Induced by Iodine Functionalization. 第52回ペプチド討論会 2015.11.16 平塚
Yuzuna Honda, Wataru Nomura, Masayuki Fujino, Tsutomu Murakami, Hirokazu Tamamura. Development of Dimeric Inhibitors Derived from a gp41 Fragment against HIV-1 Membrane Fusion Utilizing an Intermolecular Disulfide Bridge. 第52回ペプチド討論会 2015.11.16 平塚
Takayoshi Higashi, Nami Ohashi, Wataru Nomura, Hirokazu Tamamura. Development of a Highly Sensitive Assay Method for Ligand Binding with a Fluorescent Labeled PKC δC1b Domain. 第52回ペプチド討論会 2015.11.16 平塚
Wataru Nomura, Akemi Masuda, Hirokazu Tamamura. Genome Deletion by ZFN and CRISPR-Cas Targeting Promoter Region for Analysis of hTERT Function. 「細胞を創る」研究会8.0 2015.11.12 吹田
Nomura W, Honda Y, Mizuguchi T, Tamamura H. Peptidomimetic-based Mid-size Drug Research: Anti-HIV Agents. The 10th AFMC International Medicinal Chemistry Symposium 2015.10.19 Jeju, Korea
Mizuguchi T, Ohashi N, Nomura W, Murakami T, Tamamura H. An anti-HIV assay method for cell-penetrating peptides using chloroquine and identification of inhibitory peptides derived from matrix proteins. The 16th Kumamoto AIDS Seminar 2015.10.08 Kumamoto, Japan
Honda Y, Nomura W, Fujino M, Murakami T, Tamamura H. Development of dimeric inhibitors against HIV-1 fusion utilizing disulfide bonds derived from gp41 fragment peptides. The 16th Kumamoto AIDS Seminar 2015.10.07 Kumamoto, Japan
Kotani M, Irahara Y, Ishida Y, Harada S, Ohashi N, Yamada Y, Mizuguchi T, Miura T, Nomura W, Matsushita S, Yoshimura K, Tamamura H. New design of small CD4 mimic molecules targeting HIV-1 gp120. 2015.10.07 Kumamoto, Japan
Tamamura H. Development of peptide-lead anti-HIV agents and chemical biology. Department of Pharmacology and Experimental Neuroscience – Seminar Series in University of Nebraska Medical Center 2015.10.02 Omaha, USA
Honda Y, Nomura W, Fujino M, Murakami T, Tamamura H. Dimerization of C34 Derivatives with C-Terminal Disulfide Bridge and the Addition of an N-Terminal GCGG Sequence Extremely Increase HIV-1 Inhibitory Activity. The 19th Korean Peptide Protein Symposium 2015.07.06 Taean, Korea
Ohashi N, Nomura W, Minato N, Tamamura H. Development of a FRET Based PKC Ligand Screening Method. The 19th Korean Peptide Protein Symposium 2015.07.06 Taean, Korea
Tamamura H. Development of anti-HIV agents and prevention of HIV infection. Taipei Medical University-Tokyo Medical and Dental University Joint Symposium 2015: Preventive Medicine and Dentistry 2015.05.14 Tokyo, Japan
小早川 拓也. 多種のクロロアルケン型ジペプチドイソスターの合成法の開発. 13th IBB BioFuture Research Encouragement Prize研究発表会 2015.01.30 東京, 日本
Takuya Kobayakawa, Tetsuo Narumi, Hirokazu Tamamura. Development of Efficient Synthetic Methodologies of Chloroalkene Dipeptide Isosteres. 第51回ペプチド討論会 2014.10.22 徳島, 日本
Irahara Y, Kotani M, Harada S, Narumi T, Yamada Y, Hirota Y, Ohashi N, Mizuguchi T, Nomura W, Matsushita S, Yoshimura K, Tamamura H.. A New Type of Small CD4 Mimic Molecules Targeting an HIV Envelope Protein gp120.. The 15h Kumamoto AIDS Seminar. 2014
Yamada Y, Hashimoto C, Otsuki H, Hirota Y, Yoshimura K, Harada S, Ohashi N, Mizuguchi T, Nomura W, Miura T, Igarashi T, Matsushita S, Tamamura H.. A CD4 Mimic as an HIV Entry Inhibitor: Pharmacokinetics... The 15h Kumamoto AIDS Seminar. 2014
Kotani M, Hirota Y, Irahara Y, Harada S, Yamada Y, Ohashi N, Mizuguchi T, Nomura W, Matsushita S, Yoshimura K, Tamamura H.. Structure-activity Relationship Studies of CD4 Mimic Molecules.. The 15h Kumamoto AIDS Seminar. 2014
Nomura W, Métifiot M, Ohashi N, Fujino M, Mizuguchi T, Yamamoto N, Pommier Y, Komano JA, Murakami T, Tamamura H.. Cell-permeable Stapled Peptides with Integrase Inhibitory Activity Derived from HIV Gene Products.. The 15h Kumamoto AIDS Seminar. 2014
Nomura W, Hashimoto C, Fujino M, Murakami T, Ohashi N, Tamamura H.. Multimerized Peptides Derived from the C-Terminal Region of HIV-1 gp41 as Fusion Inhibitors.. The 33rd European Peptide Society Symposium. 2014
Nomura W, Masuda A, Tamamura H.. Efficient Gene Disruption at hTERT Promoter Region by Simultaneous Digestion by Pairs of ZFNs or Guide RNAs of CRISPR/Cas System.. The 28th annual symposium of protein society. 2014
Nomura W, Masuda A, Tamamura H.. Enhanced Gene Disruption at Specific Promoter Region by Simultaneous Digestion of ZFN or CRISPR/Cas System.. The Synthetic Biology: Engineering, Evolution & Design (SEED) conference 2014
Nomura W, Masuda A, Tamamura H.. Enhanced Gene Disruption by Simultaneous Digestion of ZFN or CRISPR/Cas System at hTERT Promoter Region. FASEB SRC "Genome Engineering Cutting-Edge Research and Applications” . FASEB SRC "Genome Engineering Cutting-Edge Research and Applications" 2014
Kobayakawa T, Narumi T, Tamamura H. Development of Efficient Synthetic Methodologies of Chloroalkene Dipeptide Isosteres. The 51th Japanese Peptide Symposium 2014
Mizuguchi T, Yamazaki Y, Kobayashi K, Ooe H, Iida M, Ninomiya R, Saito K, Akaji K, Tamamura H.. Studies on Identification of Active Sites of an Inhibitory Cyclic Peptide against EGF Receptor Dimerization.. The 51th Japanese Peptide Symposium 2014
Takano H, Narumi T, Nomura W, Furuta T, Tamamura H. Development of 8-Azacoumarin-4-ylmethyl-type Photolabile Protecting Groups Based on Amide-alkene Isosterism.. The 51th Japanese Peptide Symposium 2014
Honda Y, Mizuguchi T, Nomura W, Tamamura H. Development of Dimeric Peptide Derivatives Based on gp41 Fragments as HIV-1 Fusion Inhibitors. The 51th Japanese Peptide Symposium 2014
Nomura W, Koseki T, Mizuguchi T, Tamamura H. Design and Synthesis of Trivalent CXCR4 Ligands Utilizing Polyproline Linkers. The 51th Japanese Peptide Symposium 2014
Tetsuo Narumi, Takuya Kobayakawa, Hirokazu Tamamura. Design and Synthesis of Chloroalkene Dipeptide Isosteres as Ground State Peptidomimetics. The 10th Australian Peptide Conference 2013.09.08 Penang, Malaysia
Design and Synthesis of Traceable Linker for Efficient Enrichment and Specific Labeling of Target Proteins. 22nd American Peptide Symposium 2011
Synthetic Antigens for Induction of Structure-Specific Antibodies against Trimer-Form of gp41. 8th AFMC International Medicinal Chemistry Symposiu 2011
CXCR4-Derived Peptides Targeting AIDS Vaccines. 8th AFMC International Medicinal Chemistry Symposium 2011
Development of Artificial Recombinases for Genome Editing. 8th AFMC International Medicinal Chemistry Symposium 2011
Sequence-Specific Recombination Enabled by a Pair of Zinc Finger Recombinases. The 9th Australian Peptide Conference 2011
Identification of Anti-HIV Peptides Derived from Matrix Proteins. ACS Meeting Fall2011 2011
Synthesis of C1b Domains of Protein Kinase C Having Solvatochromism and their Application to Bio-sensing. The 9th Australian Peptide Conference 2011
SAR Studies of Small Molecular CD4 Mimics Targeting the HIV Entry Mechanism. 8th AFMC International Medicinal Chemistry Symposium 2011
N-(Benzoyloxy)sulfonamides-Mediated Aziridination of α, β-Unsaturated Enones. 8th AFMC International Medicinal Chemistry Symposium 2011
Synthetic Studies on (Z) and (E)-Chloroalkene Skeltons As Amide Bond Equivalents. 8th AFMC International Medicinal Chemistry Symposium 2011
Studies for Optimum Design of Artificial Zinc Finger Recombinases by Evaluation of Effects of DNA Binding Affinity and Linker Components on Recombination Efficiency. 22nd American Peptide Symposium 2011
Synthesis of HIV Gp41 Trimer Mimics Inducing Neutralizing Antibodies Based on Remodeling of Dynamic Structures of HIV-1 Envelope Proteins. 22nd American Peptide Symposium 2011
Development of Bivalent Ligands for CXCR4 with Rigid Linkers and Application to Detection of Cancer Cells. 22nd American Peptide Symposium 2011
Application of Stimulus-responsive Amino Acid to Traceable Linker for Efficient Enrichment and Specific Labeling of Target Proteins. 8th AFMC International Medicinal Chemistry Symposium 2011
Several HIV Inhibitors Targeting Entry, Fusion, Integrase and Matrix. 8th AFMC International Medicinal Chemistry Symposium 2011
Development of Photochemically Removable Protecting Groups in Hydrophilic Environments: Synthesis and Photochemical Property of 8-Azacoumarins. 8th AFMC International Medicinal Chemistry Symposium 2011
α,α-Dicholoroisoxazolidinones for The Synthesis and Chemoselective Peptide Ligation of α-Peptide α-Ketoacids. 5th International Peptide Symposium 2010
Synthesis and Evaluation of CXCR4-derived Peptides Targeting the Development of AIDS Vaccines. 5th International Peptide Symposium 2010
Novel Tag-probe Pairs for Fluorescent Imaging of Proteins in Living Cells. 5th International Peptide Symposium 2010
Development of a Bivalent Ligand for a Chemokine Receptor CXCR4 by Utilizing Polyproline Helix as a Linker. 5th International Peptide Symposium 2010
Structure-Activity Relationships of CXCR4 Antagonists Having the Dipicolylamine/Azamacro- Cyclic-Metal Complex Structures.. 11th KUMAMOTO AIDS Seminer-GCOE Joint International Symposium 2010
Strategy to Overcome Neutralization Resistance of HIV-1 Primary Isolates. 11th KUMAMOTO AIDS Seminer-GCOE Joint International Symposium 2010
Anti-HIV Inhibitors and AIDS Vaccines.. International Summer Program 2010 2010
Elucidation of a Dimerization State of a Chemokine Receptor CXCR4 via Chemical Biology Approach Utilizing Novel Bivalent Ligands with Rigid Polyproline Linkers. The 13th Akabori Conference Leipzig 2010: Japanese-German Symposium on Peptide Science 2010
Peptidic HIV Integrase Inhibitors Derived from HIV Gene Products. 11th KUMAMOTO AIDS Seminer -GCOE Joint International Symposium 2010
Effects of DNA binding and linker length on recombination of artificial zinc-finger recombinase. The 37th International Symposium on Nucleic Acids Chemistry 2010 2010
Kinetic Analysis of Split DNA Methylase in DNA Recognition and Methylation. 2010 International Chemical Congress of Pacific Basin Societies 2010
Peptidic HIV Integrase Inhibitors Derived from HIV Gene Products. Tamamura H.. 11th KUMAMOTO AIDS Seminer -GCOE Joint International Symposium 2010
Development of Small CD4 Mimic Molecules that Induce Conformational Changes in gp120. 11th KUMAMOTO AIDS Seminer-GCOE Joint International Symposium 2010
Shinohara K, Higashi-Kuwata N,Tsuji K, Ishii T, Kobayakawa T, Hattori S, Kishimoto N, Takamune N, Misumi S, Bulut H, Hayashi H, Mitsuya H, Tamamura H.. Development of novel SARS-CoV-2 main protease inhibitors with potent antiviral activity for treatment of COVID-19. The 18th Annual Meeting of Japanese Society for Chemical Biology 2024.05.28 Tokyo
Kobayakawa T, Machida S, Yokoyama M, Tsuji K, Murakami T, Sato H, Tamamura H. . Development of anti-HIV-1 agents based on a capsid protein of HIV-1. The 18th Annual Meeting of Japanese Society for Chemical Biology 2024.05.28 Tokyo
Nishimura S, Kobayakawa T, Tsuji K, Murakami T, Tamamura H. . Development of dimerized fusion inhibitors targeting the HIV-1 gp41 protein. The 18th Annual Meeting of Japanese Society for Chemical Biology 2024.05.28 Tokyo
Miura Y, Wang R, Tsuji K, Liu Y, Kobayakawa T, Harada S, Tamamura H.. Hybrids of small CD4 mimics and gp41-inhibition peptides as dual-target HIV-1 entry inhibitors. The 18th Annual Meeting of Japanese Society for Chemical Biology 2024.05.27 Tokyo
Huang X, Tsuji K, KobayakawaT, Tamamura H.. Exploratory study of polo-box domain-targeting polo-like kinase 1 degrader peptides. The 18th Annual Meeting of Japanese Society for Chemical Biology 2024.05.27 Tokyo
Yamamoto K, Kobayakawa T, Tsuji K, Tamamura H.. Development of peptidomimetics toward inhibition against amyloid-beta aggregation. The 18th Annual Meeting of Japanese Society for Chemical Biology 2024.05.27 Tokyo
Tsuji K, Huang X, Kobayakawa T, Burke TR Jr., Tamamura H.. Development of high affinity polo-like kinase 1 inhibitors based on bivalent inhibitor strategy. The 18th Annual Meeting of Japanese Society for Chemical Biology 2024.05.27 Tokyo
Takahiro Ishii, Takuya Kobayakawa, Kouki Matsuda, Kohei Tsuji, Kazuhisa Yoshimura, Hiroaki Mitsuya, Kenji Maeda, Hirokazu Tamamura. Development of PKC activators for HIV cure. The 143rd annual meeting of the pharmaceutical society of Japan 2023.03.26 Sapporo
Takahiro Ishii. Synthesis of DAG-lactone derivatives for HIV cure. 2023.01.27 Tokyo
Takahiro Ishii, Takuya Kobayakawa, Kouki Matsuda , Kohei Tsuji , Kazuhisa Yoshimura, Hiroaki Mitsuya, Kenji Maeda, Hirokazu Tamamura. Structure optimization of DAG-lactone derivatives toward HIV cure . The 16th Annual Meeting of Japanese Society for Chemical Biology 2022.05.31 Toyama
Tsutomu Murakami, Takuya Kobayakawa, Takato Onishi, Sayaka Boku, Osamu Kotani, Kohei Tsuji, Hironori Sato, and Hirokazu Tamamura. Elucidation of mechanism and derivative synthesis of a new anti-HIV-1 compound that targets the capsid dimerization interface. The 68th Annual Meeting of the Japanese Society for Virology 2021.11.16 Kobe
Takuya Kobayakawa, Kohei Tsuji, Kiju Konno, Ami Masuda, Nami Ohashi, Takeo Kuwata, Kazuhisa Yoshimura, Tomoyuki Miura, Shigeyoshi Harada, Shuzo Matsushita, Hirokazu Tamamura. CD4 mimics with PEG units as HIV entry inhibitors . The 15th Annual Meeting of Japanese Society for Chemical Biology 2021.06.23 Online
Kohei Takahashi, Ami Masuda, Shigeyoshi Harada, Takuya Kobayakawa, Yusuke Ishida, Yu Irahara, Tomoyuki Miura, Shuzo Matsushita, Kazuhisa Yoshimura, Hirokazu Tamamura. Novel CD4 mimics Increase the Activity of HIV Neutralizing Antibodies. The 37th Medicinal Chemistry Symposium 2019.11.28 Tokyo
Maxwell M. Sakyiamah, Wataru Nomura, Takuya Kobayakawa, Hirokazu Tamamura. Development of a NanoBRET-based sensitive screening method for CXCR4 ligands . The 14th Annual Meeting of Japanese Society for Chemical Biology 2019.06.10 Aichi
Kohei Takahashi, Ami Masuda, Shigeyoshi Harada, Takuya Kobayakawa, Yusuke Ishida, Yu Irahara, Tomoyuki Miura, Shuzo Matsushita, Kazuhisa Yoshimura, Hirokazu Tamamura. Novel CD4 mimics Increase the Activity of HIV Neutralizing Antibodies. 2018.11.28 Kyoto, Japan
Takuya Kobayakawa, Hirokazu Tamamura. Development of peptidomimetics based on a chloroalkene structure. 44th Symposium on Progress in Organic Reactions and Syntheses 2018.11.05 Kumamoto, Japan
Kohei Takahashi, Ami Masuda, Shigeyoshi Harada, Takuya Kobayakawa, Yusuke Ishida, Yu Irahara, Tomoyuki Miura, Shuzo Matsushita, Kazuhisa Yoshimura, Hirokazu Tamamura. Development of novel small molecule CD4 mimics with anti-HIV activity. The 13th Annual Meeting of Japanese Society for Chemical Biology 2018.06.13
Kento Ebihara, Yuzuna Honda, Takuya Kobayakawa, Wataru Nomura, Tsutomu Murakami, Hirokazu Tamamura. Development of HIV-1 fusion inhibitors based on the C34 dimers derived from gp41. The 13th Annual Meeting of Japanese Society for Chemical Biology 2018.06.13 Tokyo, Japan
Daisuke Matsumoto, Wataru Nomura, Hirokazu Tamamura. Development of genome editing systems with a FokI-based chemically inducible nuclease. The 13th Annual Meeting of Japanese Society for Chemical Biology 2018.06.12 Tokyo
Wataru Nomura, Takumi Kamimura, Atsumi Mori, Takuya Kobayakawa, Hirokazu Tamamura. Peptide-based fluorescent imaging tools for observation of target protein dynamics. 138th Annual Meeting of the Pharmaceutical Society of Japan 2018.03.28 Ishikawa, Japan
Takuya Kobayakawa. Synthetic study of peptidomimetics based on chloroalkene structures. 2017.01.27
Takuya Kobayakawa. Stereoselective Formation of Trisubstituted (E)-Chloroalkenes by Organocopper Reagents. 2013.01.25 Tokyo, Japan