Outline
Our research is based on a broad range of areas such as electrochemistry, mechanical engineering, electrical engineering, material science and biochemistry. The group aims to pursue interdisciplinary research in bio-MEMS, bio-optics, bio-electronics or bioinformatics by combining biotechnology and information technology.
Research
1. Detachable “Cavitas sensors” as bioinformation monitoring systems in body cavities
"Cavitas sensors" such as a soft contact-lens biosensor and a mouth guard biosensor have been developed for novel biomonitoring methods by using advanced polymer microelectromechanical systems (MEMS) techniques.
2. Biochemical gas sensor "Bio-sniffers" and spatiotemporal gas visualization system “Sniff-camera” for volatile organic compounds from human body
Highly selective gas sensors "Bio-sniffers" and gas visualization systems "Sniff-camera" for acquiring spatiotemporal information of distribution of volatile chemicals have been developed by exploiting metabolizing enzymes in human liver. Potential applications of these gas sensors include halitosis analysis, breath alcohol and aldehyde measurement, medical screening or dental health, etc.
3. Immunosensors for medical treatment and environmental medicine
Development of optical or surface acoustic wave immunosensors have been pursued for semi-continuos (rapid and repeated) measurement of antigens in body and airborne allergens in living environment.
4. “Organic engine” and “Air bio-battery” based on chemo-mechanical energy conversion
Novel chemo-mechanical energy conversion systems (Organic engine and Air bio-battery) that utilize enzyme reactions and active transport of chemicals has been constructed. Biomedical applications (chemical pumps, drug release systems, etc.) are also investigated.
Education
In advanced medicine, technologies enabling to accurately measure biological information are highly demanded. The development of “human-friendly” non-invasive measurement methods could release patients from the pain and the risks of sampling. The students will learn the basic knowledge and skills of biological information measurement through the lectures (e.g., “Biomedical Engineering”, “Biomedical Device Science and Engineering”, “Wearable & IoT Devices and Applications”, "Advanced Biomedical Devices", "Integrative Biomedical Sciences for Preemptive Medicine", and "Advanced Medical Device and System"), seminars and practical training. Especially research including biochemical measurement, the development of biosensing devices and their applications to medicine will be carried out based on “sensor and biomedical engineering.
Lectures & Courses
The students will learn the basic technology related to advanced medicine and biological information measurement. Through practical training, they will also engage in research activities for biochemical measurement, the development of biosensing devices and their applications to medicine based on “sensor and biomedical engineering”. The objective of this course is to help the students be able to think about and conduct a research by themselves throughout the activities with academic researches.