Surgical technology has been improving follows to the development of advanced instruments and therapeutic strategies. On the one hand, innovation in surgery inevitably requires individual operator's skill and tailoring of the intervention to the patient. The aim of our laboratory is research and development of developmental pathway for modern surgical technology through the large animal experiment. Following to the framework for the stages in surgical innovation, such as ideas, development, exploration, assessment and pre-clinical study, we will serve as a mediator between basic science and clinical practice. And more, implementation of human resources development in the field of advanced surgery is also another intention of our laboratory.