Department of Clinical Bioanalysis and Molecular Biology

141  articles.  
* There may be some overlapped articles listed due to the difference of format.

  1. Akiko Futatsugi, Minoru Tozuka, Yuna Horiuchi, Ryunosuke Ohkawa, Tomoki Kosho: High-density lipoprotein functionality in cholesterol efflux in early childhood is related to the content ratio of triglyceride to cholesterol. Sci Rep. 2024.10; 14 (1): 23323. ( PubMed , DOI )

  1. Masamichi Mikame, Nelson Hirokazu Tsuno, Yoshino Miura, Hideaki Kitazaki, Daisuke Uchimura, Toru Miyazaki, Toru Miyagi, Takayuki Onodera, Wataru Ohashi, Takahiro Kameda, Ryunosuke Ohkawa, Shuichi Kino, Kazuo Muroi: Decreased rate of blood donors with high ABO antibody titers in Japan and the underlying factors: Comparisons between 2010 and 2021. Transfus Apher Sci. 2023.12; 62 (6): 103812. ( PubMed , DOI )

  2. Masamichi Mikame, Nelson Hirokazu Tsuno, Yoshino Miura, Hideaki Kitazaki, Daisuke Uchimura, Toru Miyagi, Toru Miyazaki, Takayuki Onodera, Wataru Ohashi, Takahiro Kameda, Ryunosuke Ohkawa, Shuichi Kino, Kazuo Muroi.: Anti-A and anti-B titers, age, gender, biochemical parameters, and body mass index in Japanese blood donors. Immunohematology. 2023.12; 39 (4): 155-165. ( PubMed , DOI )

  3. Azusa Yamazaki, Yoko Nukui, Takahiro Kameda, Ryoichi Saito, Yuki Koda, Naoya Ichimura, Shuji Tohda, Ryunosuke Ohkawa: Variation in presepsin and thrombomodulin levels for predicting COVID-19 mortality. Sci Rep. 2023.12; 13 (1): 21493. ( PubMed , DOI )

  4. Shao-Jui Lai, Takahiro Kameda, Maasa Morita, Yuka Yamagata, Kaoruko Nishizaka, Yuna Horiuchi, Yukihiro Kobayashi, Yoko Usami, Jun-Jen Liu, Takeshi Kasama, Minoru Tozuka, Ryunosuke Ohkawa: Characterization of novel truncated apolipoprotein A-I in human high-density lipoprotein generated by sequential treatment with myeloperoxidase and chymase. Biochimie. 2023.09; 218 34-45. ( PubMed , DOI )

  5. Tsunehiro Miyakoshi, Yume Mutsuda, Yuna Horiuchi, Takahiro Kameda, Minoru Tozuka, Ryunosuke Ohkawa: Improvement in bilirubin influence on cholesterol efflux capacity evaluation using the immobilized liposome-bound gel beads method. Biosci Rep. 2023.06; 43 (6): ( PubMed , DOI )

  6. Ohkawa R.: Quiz Section!! APFCB News. 2023.03; 1 99-102.

  7. Yume Mutsuda, Tsunehiro Miyakoshi, Yuna Horiuchi, Takahiro Kameda, Minoru Tozuka, Ryunosuke Ohkawa: Development and validation of novel automatable assay for cholesterol efflux capacity. Biosci Rep. 2023.02; 43 (2): ( PubMed , DOI )

  1. Momona Yamada, Miho Iwase, Binri Sasaki, Nobuharu Suzuki: The molecular regulation of oligodendrocyte development and CNS myelination by ECM proteins Frontiers in Cell and Developmental Biology. 2022.09; 10 952135.

  2. Ogino M, Kameda T, Mutsuda Y, Tanaka H, Takahashi J, Okazaki M, Ai M, Ohkawa R: Development of internal standard for lipoprotein subclass analysis using dual detection gel-permeation high-performance liquid chromatography system. Bioscience reports. 2022.05; 42 (6): ( PubMed , DOI )

  3. Yuna Horiuchi, Shao-Jui Lai, Takahiro Kameda, Minoru Tozuka, Ryunosuke Ohkawa: Novel cholesterol efflux assay using immobilized liposome-bound gel beads: Confirmation and improvement for application in clinical laboratory. Ann Clin Biochem. 2022.03; 59 (2): 134-143. ( PubMed , DOI )

  1. Takahiro Kameda, Yuna Horiuchi, Shitsuko Shimano, Kouji Yano, Shao-Jui Lai, Naoya Ichimura, Shuji Tohda, Yuriko Kurihara, Minoru Tozuka, Ryunosuke Ohkawa: N-homocysteinylation of high-density lipoprotein on endothelial repair function. Biol Chem. 2021.08; ( PubMed , DOI )

  2. Tamaki Kobayashi, Makoto Kurano, Mai Nanya, Tomo Shimizu, Ryunosuke Ohkawa, Minoru Tozuka, Yutaka Yatomi: Glycation of HDL Polymerizes Apolipoprotein M and Attenuates Its Capacity to Bind to Sphingosine 1-Phosphate. J Atheroscler Thromb. 2021.07; 28 (7): 730-741. ( PubMed , DOI )

  3. Azusa Yamazaki, Ryunosuke Ohkawa, Yuka Yamagata, Yuna Horiuchi, Shao-Jui Lai, Takahiro Kameda, Naoya Ichimura, Shuji Tohda, Minoru Tozuka: Apolipoprotein C-II and C-III preferably transfer to both high-density lipoprotein (HDL)2 and the larger HDL3 from very low-density lipoprotein (VLDL). Biol Chem. 2021.05; 402 (4): 439-449. ( PubMed , DOI )

  4. Yasunori Iwata, Shinji Kitajima, Junya Yamahana, Shuji Shimomura, Shiori Yoneda-Nakagawa, Norihiko Sakai, Kengo Furuichi, Hisayuki Ogura, Koichi Sato, Tadashi Toyama, Yuta Yamamura, Taro Miyagawa, Akinori Hara, Miho Shimizu, Ryunosuke Ohkawa, Makoto Kurano, Yutaka Yatomi, Takashi Wada: Higher serum levels of autotaxin and phosphatidylserine-specific phospholipase A1 in patients with lupus nephritis Int J Rheum Dis. 2021.02; 24 (2): 231-239. ( PubMed , DOI )

  5. Shitsuko Shimano, Ryunosuke Ohkawa, Mayu Nambu, Mai Sasaoka, Azusa Yamazaki, Yuki Fujii, Yuna Horiuchi, Shao-Jui Lai, Takahiro Kameda, Naoya Ichimura, Koji Fujita, Shuji Tohda, Minoru Tozuka: Marked Changes in Serum Amyloid A Distribution and High-Density Lipoprotein Structure during Acute Inflammation. Biomed Res Int. 2021; 2021 9241259. ( PubMed , DOI )

  1. Ryunosuke Ohkawa, Hann Low, Nigora Mukhamedova, Ying Fu, Shao-Jui Lai, Mai Sasaoka, Ayuko Hara, Azusa Yamazaki, Takahiro Kameda, Yuna Horiuchi, Peter J Meikle, Gerard Pernes, Graeme Lancaster, Michael Ditiatkovski, Paul Nestel, Boris Vaisman, Denis Sviridov, Andrew Murphy, Alan T Remaley, Dmitri Sviridov, Minoru Tozuka: Cholesterol transport between red blood cells and lipoproteins contributes to cholesterol metabolism in blood. J Lipid Res. 2020.12; 61 (12): 1577-1588. ( PubMed , DOI )

  2. Hann Low, Nigora Mukhamedova, Luciano Dos Santos Aggum Capettini, Yining Xia, Irena Carmichael, Stephen H Cody, Kevin Huynh, Michael Ditiatkovski, Ryunosuke Ohkawa, Michael Bukrinsky, Peter J Meikle, Soo-Ho Choi, Seth Field, Yury I Miller, Dmitri Sviridov: Cholesterol Efflux-Independent Modification of Lipid Rafts by AIBP (Apolipoprotein A-I Binding Protein). Arterioscler. Thromb. Vasc. Biol.. 2020.08; 40 (10): ATVBAHA120315037. ( PubMed , DOI )

  3. Yuna Horiuchi, Shao-Jui Lai, Takahiro Kameda, Minoru Tozuka, Ryunosuke Ohkawa: Comparison of a novel cholesterol efflux assay using immobilized liposome-bound gel beads with the conventional method. Biosci. Rep.. 2020.07; ( PubMed , DOI )

  4. Chikako Hayashi, Nobuharu Suzuki, Riko Takahashi, Chihiro Akazawa: Development of type I/II oligodendrocytes regulated by teneurin-4 in the murine spinal cord. Sci Rep. 2020.05; 10 (1): 8611. ( PubMed , DOI )

  5. Chikako Hayashi, Nobuharu Suzuki, Yo Mabuchi, Naomi Kikura, Yukina Hosoda, Susana de Vega, Chihiro Akazawa: The extracellular domain of teneurin-4 promotes cell adhesion for oligodendrocyte differentiation. Biochem Biophys Res Commun. 2020.02; 523 (1): 171-176. ( PubMed , DOI )

  1. Nobuharu Suzuki, Mai Hyodo, Chikako Hayashi, Yo Mabuchi, Kaori Sekimoto, Chinami Onchi, Kiyotoshi Sekiguchi, Chihiro Akazawa: Laminin α2, α4, and α5 Chains Positively Regulate Migration and Survival of Oligodendrocyte Precursor Cells. Sci Rep. 2019.12; 9 (1): 19882. ( PubMed , DOI )

  2. Chikako Hayashi, Nobuharu Suzuki: Heterogeneity of Oligodendrocytes and Their Precursor Cells. Adv. Exp. Med. Biol.. 2019.11; 1190 53-62. ( PubMed , DOI )

  3. Nigora Mukhamedova, Anh Hoang, Dragana Dragoljevic, Larisa Dubrovsky, Tatiana Pushkarsky, Hann Low, Michael Ditiatkovski, Ying Fu, Ryunosuke Ohkawa, Peter J Meikle, Anelia Horvath, Beda Brichacek, Yury I Miller, Andrew Murphy, Michael Bukrinsky, Dmitri Sviridov: Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells. PLoS Pathog.. 2019.07; 15 (7): e1007907. ( PubMed , DOI )

  4. Horiuchi Y., Ohkawa R., Lai S., Shimano S., Hagihara M., Tohda S., Tozuka M.: Availability of ApoB-depleted serum in clinical assay for cholesterol efflux capacity using immobilized liposome-bound gel beads CLINICA CHIMICA ACTA. 2019.06; 493 S78-S79. ( DOI )

  5. Shao-Jui Lai, Ryunosuke Ohkawa, Yuna Horiuchi, Tetsuo Kubota, Minoru Tozuka: Red blood cells participate in reverse cholesterol transport by mediating cholesterol efflux of high-density lipoprotein and apolipoprotein A-I from THP-1 macrophages. Biol. Chem.. 2019.06; ( PubMed , DOI )

  6. Yuna Horiuchi, Ryunosuke Ohkawa, Shao-Jui Lai, Shitsuko Shimano, Michio Hagihara, Shuji Tohda, Takahiro Kameda, Minoru Tozuka: Usefulness of apolipoprotein B-depleted serum in cholesterol efflux capacity assays using immobilized liposome-bound gel beads. Biosci. Rep.. 2019.03; ( PubMed , DOI )

  7. Yuna Horiuchi, Ryunosuke Ohkawa, Shao-Jui Lai, Azusa Yamazaki, Hayato Ikoma, Kouji Yano, Takahiro Kameda, Minoru Tozuka: Characterization of the cholesterol efflux of apolipoprotein E-containing high-density lipoprotein in THP-1 cells. Biol. Chem.. 2019.01; 400 (2): 209-218. ( PubMed , DOI )

  8. Megumi Sato, Ryunosuke Ohkawa, Hann Low, Madoka Nishimori, Shigeo Okubo, Akira Yoshimoto, Kouji Yano, Takahiro Kameda, Yutaka Yatomi, Minoru Tozuka: Serum amyloid A does not affect high-density lipoprotein cholesterol measurement by a homogeneous assay. Clin. Biochem.. 2019.01; 63 97-101. ( PubMed , DOI )

  1. Yuko Mishima, Makoto Kurano, Tamaki Kobayashi, Masako Nishikawa, Ryunosuke Ohkawa, Minoru Tozuka, Yutaka Yatomi: Dihydro-sphingosine 1-phosphate interacts with carrier proteins in a manner distinct from that of sphingosine 1-phosphate. Biosci. Rep.. 2018.10; 38 (5): ( PubMed , DOI )

  2. Hitoshi Ikeda, Mariko Kobayashi, Hiromitsu Kumada, Kenichiro Enooku, Kazuhiko Koike, Makoto Kurano, Masaya Sato, Takahiro Nojiri, Tamaki Kobayashi, Ryunosuke Ohkawa, Satoshi Shimamoto, Koji Igarashi, Junken Aoki, Yutaka Yatomi: Performance of autotaxin as a serum marker for liver fibrosis. Ann. Clin. Biochem.. 2018.07; 55 (4): 469-477. ( PubMed , DOI )

  3. Horiuchi, Y; Lai, SJ; Yamazaki, A; Nakamura, A; Ohkawa, R; Yano, K; Kameda, T; Okubo, S; Shimano, S; Hagihara, M; Tohda, S; Tozuka, M: VALIDATION AND APPLICATION OF A NOVEL CHOLESTEROL EFFLUX ASSAY USING IMMOBILIZED LIPOSOMES AS A SUBSTITUTE FOR CULTURED CELLS ATHEROSCLEROSIS SUPPLEMENTS. 2018.06; 32 59. ( DOI )

  4. Ogata Yusuke, Mabuchi Yo, Shinoda Kosuke, Horiike Yuta, Mizuno Mitsuru, Otabe Koji, Suto Eriko Grace, Suzuki Nobuharu, Sekiya Ichiro, Akazawa Chihiro: Anterior cruciate ligament-derived mesenchymal stromal cells have a propensity to differentiate into the ligament lineage Regenerative Medicine. 2018.06; 8 20-28. ( PubMed , DOI )

  5. Yuna Horiuchi, Shao-Jui Lai, Azusa Yamazaki, Ayaka Nakamura, Ryunosuke Ohkawa, Kouji Yano, Takahiro Kameda, Shigeo Okubo, Shitsuko Shimano, Michio Hagihara, Shuji Tohda, Minoru Tozuka: Validation and application of a novel cholesterol efflux assay using immobilized liposomes as a substitute for cultured cells. Biosci. Rep.. 2018.04; 38 (2): ( PubMed , DOI )

  6. Ryunosuke Ohkawa, Makoto Kurano, Noboru Sakai, Tatsuya Kishimoto, Takahiro Nojiri, Koji Igarashi, Shigemi Hosogaya, Yukio Ozaki, Tomotaka Dohi, Katsumi Miyauchi, Hiroyuki Daida, Junken Aoki, Shigeo Okubo, Hitoshi Ikeda, Minoru Tozuka, Yutaka Yatomi: Measurement of plasma choline in acute coronary syndrome: importance of suitable sampling conditions for this assay. Sci. Rep.. 2018.03; 8 (1): 4725. ( PubMed , DOI )

  7. Kana Ishii, Hidetoshi Sakurai, Nobuharu Suzuki, Yo Mabuchi, Ichiro Sekiya, Kiyotoshi Sekiguchi, Chihiro Akazawa: Recapitulation of Extracellular LAMININ Environment Maintains Stemness of Satellite Cells In Vitro. Stem Cell Reports. 2018.02; 10 (2): 568-582. ( PubMed , DOI )

  1. Ishii Kana, Suzuki Nobuharu, Mabuchi Yo, Sekiya Ichiro, Akazawa Chihiro: Technical advantage of recombinant collagenase for isolation of muscle stem cells REGENERATIVE THERAPY. 2017.12; 7 1-7. ( PubMed , DOI )

  2. Nobuharu Suzuki, Kaori Sekimoto, Chikako Hayashi, Yo Mabuchi, Tetsuya Nakamura, Chihiro Akazawa: Differentiation of Oligodendrocyte Precursor Cells from Sox10-Venus Mice to Oligodendrocytes and Astrocytes. Sci Rep. 2017.10; 7 (1): 14133. ( PubMed , DOI )

  3. Eriko Grace Suto, Yo Mabuchi, Nobuharu Suzuki, Koji Suzuki, Yusuke Ogata, Miyu Taguchi, Takeshi Muneta, Ichiro Sekiya, Chihiro Akazawa: Prospectively isolated mesenchymal stem/stromal cells are enriched in the CD73(+) population and exhibit efficacy after transplantation. Sci Rep. 2017.07; 7 (1): 4838. ( PubMed , DOI )

  4. Hassan Ahmed, Dohi Tomotaka, Miyauchi Katsumi, Ogita Manabu, Kurano Makoto, Ohkawa Ryunosuke, Nakamura Kazuhiro, Tamura Hiroshi, Isoda Kikuo, Okazaki Shinya, Yatomi Yutaka, Daida Hiroyuki: Homocysteine値とhomocysteine thiolactonase活性が経皮冠動脈インターベンションを受ける患者の長期臨床アウトカムに与える予後的影響(Prognostic impact of homocysteine levels and homocysteine thiolactonase activity on long-term clinical outcomes in patients undergoing percutaneous coronary intervention) Journal of Cardiology. 2017.06; 69 (5-6): 830-835. ( ichushi )

  5. Makoto Kurano, Kuniyuki Kano, Tomotaka Dohi, Hirotaka Matsumoto, Koji Igarashi, Masako Nishikawa, Ryunosuke Ohkawa, Hitoshi Ikeda, Katsumi Miyauchi, Hiroyuki Daida, Junken Aoki, Yutaka Yatomi: Different origins of lysophospholipid mediators between coronary and peripheral arteries in acute coronary syndrome. J. Lipid Res.. 2017.02; 58 (2): 433-442. ( PubMed , DOI )

  1. Yoshimoto, A., Ohkawa, R., Yano, K., Sato, M., Ichimura, N., Usami, Y., Miyazaki, A., Sugano, M., Uehara, T., and Tozuka, M.: Paraoxonase 1 associated with high-density lipoprotein transfers to oxidized low-density lipoprotein depending on the degree of oxidation. Int J Anal Bio-Sci. 2016.12; 4 (4): 99-109.

  2. Y Nagura, N H Tsuno, K Kano, A Inoue, J Aoki, Y Hirowatari, M Kaneko, M Kurano, M Matsuhashi, R Ohkawa, M Tozuka, Y Yatomi, H Okazaki: Regulation of the lysophosphatidylserine and sphingosine 1-phosphate levels in autologous whole blood by the pre-storage leukocyte reduction. Transfus Med. 2016.10; 26 (5): 365-372. ( PubMed , DOI )

  3. Ahmed Hassan, Tomotaka Dohi, Katsumi Miyauchi, Manabu Ogita, Makoto Kurano, Ryunosuke Ohkawa, Kazuhiro Nakamura, Hiroshi Tamura, Kikuo Isoda, Shinya Okazaki, Yutaka Yatomi, Hiroyuki Daida: Prognostic impact of homocysteine levels and homocysteine thiolactonase activity on long-term clinical outcomes in patients undergoing percutaneous coronary intervention. J Cardiol. 2016.09; 69 (6): 830-835. ( PubMed , DOI )

  4. Megumi Sato, Ryunosuke Ohkawa, Akira Yoshimoto, Kouji Yano, Naoya Ichimura, Madoka Nishimori, Shigeo Okubo, Yutaka Yatomi, Minoru Tozuka: Effects of serum amyloid A on the structure and antioxidant ability of high-density lipoprotein. Biosci. Rep.. 2016.07; ( PubMed , DOI )

  5. Susana de Vega, Kentaro Hozumi, Nobuharu Suzuki, Risa Nonaka, Eimi Seo, Anna Takeda, Tomoko Ikeuchi, Motoyoshi Nomizu, Yoshihiko Yamada, Eri Arikawa-Hirasawa: Identification of peptides derived from the C-terminal domain of fibulin-7 active for endothelial cell adhesion and tube formation disruption. Biopolymers. 2016.03; 106 (2): 184-195. ( PubMed , DOI )

  6. Kouji Yano, Ryunosuke Ohkawa, Megumi Sato, Akira Yoshimoto, Naoya Ichimura, Takahiro Kameda, Tetsuo Kubota, Minoru Tozuka: Cholesterol Efflux Capacity of Apolipoprotein A-I Varies with the Extent of Differentiation and Foam Cell Formation of THP-1 Cells. J Lipids. 2016; 2016 9891316. ( PubMed , DOI )

  7. Naoya Ichimura, Megumi Sato, Akira Yoshimoto, Kouji Yano, Ryunosuke Ohkawa, Takeshi Kasama, Minoru Tozuka: High-Density Lipoprotein Binds to Mycobacterium avium and Affects the Infection of THP-1 Macrophages. J Lipids. 2016; 2016 4353620. ( PubMed , DOI )

  8. Miho Shimizu, Kengo Furuichi, Tadashi Toyama, Junya Yamahana, Ryunosuke Ohkawa, Koji Igarashi, Junken Aoki, Shuichi Kaneko, Yutaka Yatomi, Takashi Wada: Serum Autotaxin Levels Are Associated with Proteinuria and Kidney Lesions in Japanese Type 2 Diabetic Patients with Biopsy-proven Diabetic Nephropathy. Intern. Med.. 2016; 55 (3): 215-221. ( PubMed , DOI )

  1. Kana Ishii, Nobuharu Suzuki, Yo Mabuchi, Naoki Ito, Naomi Kikura, So-Ichiro Fukada, Hideyuki Okano, Shin'ichi Takeda, Chihiro Akazawa: Muscle Satellite Cell Protein Teneurin-4 Regulates Differentiation During Muscle Regeneration. Stem Cells. 2015.10; 33 (10): 3017-3027. ( PubMed , DOI )

  2. Ryunosuke Ohkawa, Makoto Kurano, Yuko Mishima, Takahiro Nojiri, Yasunori Tokuhara, Tatsuya Kishimoto, Kazuhiro Nakamura, Shigeo Okubo, Shigemi Hosogaya, Yukio Ozaki, Hiromitsu Yokota, Koji Igarashi, Hitoshi Ikeda, Minoru Tozuka, Yutaka Yatomi: Possible involvement of sphingomyelin in the regulation of the plasma sphingosine 1-phosphate level in human subjects. Clin. Biochem.. 2015.07; 48 (10-11): 690-697. ( PubMed , DOI )

  3. Yusuke Ogata, Yo Mabuchi, Mayu Yoshida, Eriko Grace Suto, Nobuharu Suzuki, Takeshi Muneta, Ichiro Sekiya, Chihiro Akazawa: Purified Human Synovium Mesenchymal Stem Cells as a Good Resource for Cartilage Regeneration. PLoS ONE. 2015.06; 10 (6): e0129096. ( PubMed , DOI )

  4. High capacity of purified mesenchymal stem cells for cartilage regeneration 2015.04;

  5. Makoto Kurano, Akiko Suzuki, Asuka Inoue, Yasunori Tokuhara, Kuniyuki Kano, Hirotaka Matsumoto, Koji Igarashi, Ryunosuke Ohkawa, Kazuhiro Nakamura, Tomotaka Dohi, Katsumi Miyauchi, Hiroyuki Daida, Kazuhisa Tsukamoto, Hitoshi Ikeda, Junken Aoki, Yutaka Yatomi: Possible involvement of minor lysophospholipids in the increase in plasma lysophosphatidic Acid in acute coronary syndrome. Arterioscler. Thromb. Vasc. Biol.. 2015.02; 35 (2): 463-470. ( PubMed , DOI )

  6. Makoto Kurano, Kazuhisa Tsukamoto, Masumi Hara, Ryunosuke Ohkawa, Hitoshi Ikeda, Yutaka Yatomi: LDL Receptor and ApoE Are Involved in the Clearance of ApoM-associated Sphingosine 1-Phosphate. J. Biol. Chem.. 2015.01; 290 (4): 2477-2488. ( PubMed , DOI )

  7. Takahiro Kameda, Ryunosuke Ohkawa, Kouji Yano, Yoko Usami, Akari Miyazaki, Kazuyuki Matsuda, Kenji Kawasaki, Mitsutoshi Sugano, Tetsuo Kubota, Minoru Tozuka: Effects of Myeloperoxidase-Induced Oxidation on Antiatherogenic Functions of High-Density Lipoprotein. J Lipids. 2015; 2015 592594. ( PubMed , DOI )

  1. Satoshi Nishimura, Mika Nagasaki, Shinichi Okudaira, Junken Aoki, Tsukasa Ohmori, Ryunosuke Ohkawa, Kazuhiro Nakamura, Koji Igarashi, Hiroshi Yamashita, Koji Eto, Kansei Uno, Naoto Hayashi, Takashi Kadowaki, Issei Komuro, Yutaka Yatomi, Ryozo Nagai: ENPP2 contributes to adipose tissue expansion and insulin resistance in diet-induced obesity. Diabetes. 2014.12; 63 (12): 4154-4164. ( PubMed , DOI )

  2. Kenichiro Enooku, Hayato Nakagawa, Yoko Soroida, Ryunosuke Ohkawa, Yuko Kageyama, Baasanjav Uranbileg, Naoko Watanabe, Ryosuke Tateishi, Haruhiko Yoshida, Kazuhiko Koike, Yutaka Yatomi, Hitoshi Ikeda: Increased serum mitochondrial creatine kinase activity as a risk for hepatocarcinogenesis in chronic hepatitis C patients. Int. J. Cancer. 2014.08; 135 (4): 871-879. ( PubMed , DOI )

  3. Nobuharu Suzuki, Chihiro Mizuniwa, Kana Ishii, Yusuke Nakagawa, Kunikazu Tsuji, Takeshi Muneta, Ichiro Sekiya, Chihiro Akazawa: Teneurin-4, a transmembrane protein, is a novel regulator that suppresses chondrogenic differentiation. J. Orthop. Res.. 2014.07; 32 (7): 915-922. ( PubMed , DOI )

  4. Shiori Ito, Soichiro Iwaki, Rie Kondo, Masashi Satoh, Kazuya Iwabuchi, Ryunosuke Ohkawa, Yuko Mishima, Yutaka Yatomi, Tomoo Furumoto, Hiroyuki Tsutsui, Satoshi Fujii: TNF-α production in NKT cell hybridoma is regulated by sphingosine-1-phosphate: implications for inflammation in atherosclerosis. Coron. Artery Dis.. 2014.06; 25 (4): 311-320. ( PubMed , DOI )

  5. Mayuko Kondo, Takeaki Ishizawa, Kenichiro Enooku, Yasunori Tokuhara, Ryunosuke Ohkawa, Baasanjav Uranbileg, Hayato Nakagawa, Ryosuke Tateishi, Haruhiko Yoshida, Norihiro Kokudo, Kazuhiko Koike, Yutaka Yatomi, Hitoshi Ikeda: Increased serum autotaxin levels in hepatocellular carcinoma patients were caused by background liver fibrosis but not by carcinoma. Clin. Chim. Acta. 2014.06; 433 128-134. ( PubMed , DOI )

  6. Baasanjav Uranbileg, Kenichiro Enooku, Yoko Soroida, Ryunosuke Ohkawa, Yotaro Kudo, Hayato Nakagawa, Ryosuke Tateishi, Haruhiko Yoshida, Seiko Shinzawa, Kyoji Moriya, Natsuko Ohtomo, Takako Nishikawa, Yukiko Inoue, Tomoaki Tomiya, Soichi Kojima, Tomokazu Matsuura, Kazuhiko Koike, Yutaka Yatomi, Hitoshi Ikeda: High ubiquitous mitochondrial creatine kinase expression in hepatocellular carcinoma denotes a poor prognosis with highly malignant potential. Int. J. Cancer. 2014.05; 134 (9): 2189-2198. ( PubMed , DOI )

  7. Susana de Vega, Nobuharu Suzuki, Risa Nonaka, Takako Sasaki, Patricia Forcinito, Eri Arikawa-Hirasawa, Yoshihiko Yamada: A C-terminal fragment of fibulin-7 interacts with endothelial cells and inhibits their tube formation in culture. Arch Biochem Biophys. 2014.03; 545 148-153. ( PubMed , DOI )

  8. Nobuharu Suzuki, Tadahiro Numakawa, Joshua Chou, Susana de Vega, Chihiro Mizuniwa, Kaori Sekimoto, Naoki Adachi, Hiroshi Kunugi, Eri Arikawa-Hirasawa, Yoshihiko Yamada, Chihiro Akazawa: Teneurin-4 promotes cellular protrusion formation and neurite outgrowth through focal adhesion kinase signaling. FASEB J. 2014.03; 28 (3): 1386-1397. ( PubMed , DOI )

  9. Ryota Suzuki, Katsumi Miyahara, Hiroshi Murakami, Takashi Doi, Geoffrey J Lane, Yo Mabuchi, Nobuharu Suzuki, Atsuyuki Yamataka, Chihiro Akazawa: Abnormal neural crest innervation in Sox10-Venus mice with all-trans retinoic acid-induced anorectal malformations. Pediatr Surg Int. 2014.02; 30 (2): 189-195. ( PubMed , DOI )

  10. Junko Iino, Makoto Osada, Makoto Kurano, Makoto Kaneko, Ryunosuke Ohkawa, Yumiko Satoh, Shigeo Okubo, Yukio Ozaki, Minoru Tozuka, Nelson H Tsuno, Yutaka Yatomi: Platelet-derived sphingosine 1-phosphate induces migration of Jurkat T cells. Lipids Health Dis. 2014; 13 150. ( PubMed , DOI )

  11. Yasunori Tokuhara, Kenichi Shukuya, Masami Tanaka, Mariko Mouri, Ryunosuke Ohkawa, Midori Fujishiro, Tomoo Takahashi, Shigeo Okubo, Hiromitsu Yokota, Makoto Kurano, Hitoshi Ikeda, Seiji Yamaguchi, Shinobu Inagaki, Mika Ishige-Wada, Hiromi Usui, Yutaka Yatomi, Tatsuo Shimosawa: Detection of novel visible-light region absorbance peaks in the urine after alkalization in patients with alkaptonuria. PLoS ONE. 2014; 9 (1): e86606. ( PubMed , DOI )

  1. Shiori Ito, Soichiro Iwaki, Keiko Koike, Yuichiro Yuda, Ayako Nagasaki, Ryunosuke Ohkawa, Yutaka Yatomi, Tomoo Furumoto, Hiroyuki Tsutsui, Burton E Sobel, Satoshi Fujii: Increased plasma sphingosine-1-phosphate in obese individuals and its capacity to increase the expression of plasminogen activator inhibitor-1 in adipocytes. Coron. Artery Dis.. 2013.12; 24 (8): 642-650. ( PubMed , DOI )

  2. Yutaka Nagura, Nelson H Tsuno, Ryunosuke Ohkawa, Takahiro Nojiri, Yasunori Tokuhara, Mika Matsuhashi, Yutaka Yatomi, Koki Takahashi: Inhibition of lysophosphatidic acid increase by prestorage whole blood leukoreduction in autologous CPDA-1 whole blood. Transfusion. 2013.12; 53 (12): 3139-3148. ( PubMed , DOI )

  3. R Kanai, T Iijima, S Hashimoto, H Nakazawa, H Ohnishi, T Yorozu, R Ohkawa, T Nojiri, M Shimizu, H Okazaki: Impact of immunoreactive substances contained in apheresis platelet concentrate on postoperative respiratory function in surgical patients receiving platelet transfusion: a prospective cohort study. Transfus Med. 2013.10; 23 (5): 344-350. ( PubMed , DOI )

  4. Yoshishige Miyabe, Chie Miyabe, Yoshiko Iwai, Aiko Takayasu, Shin Fukuda, Waka Yokoyama, Jun Nagai, Masahiro Jona, Yasunori Tokuhara, Ryunosuke Ohkawa, Harald M Albers, Huib Ovaa, Junken Aoki, Jerold Chun, Yutaka Yatomi, Hiroshi Ueda, Masayuki Miyasaka, Nobuyuki Miyasaka, Toshihiro Nanki: Necessity of lysophosphatidic acid receptor 1 for development of arthritis. Arthritis Rheum.. 2013.08; 65 (8): 2037-2047. ( PubMed , DOI )

  5. Tomotaka Dohi, Katsumi Miyauchi, Ryunosuke Ohkawa, Kazuhiro Nakamura, Makoto Kurano, Tatsuya Kishimoto, Naotake Yanagisawa, Manabu Ogita, Tadashi Miyazaki, Akihisa Nishino, Kenji Yaginuma, Hiroshi Tamura, Takahiko Kojima, Ken Yokoyama, Takeshi Kurata, Kazunori Shimada, Hiroyuki Daida, Yutaka Yatomi: Increased lysophosphatidic acid levels in culprit coronary arteries of patients with acute coronary syndrome. Atherosclerosis. 2013.07; 229 (1): 192-197. ( PubMed , DOI )

  6. Makoto Kurano, Kazuhisa Tsukamoto, Ryunosuke Ohkawa, Masumi Hara, Junko Iino, Yuko Kageyama, Hitoshi Ikeda, Yutaka Yatomi: Liver involvement in sphingosine 1-phosphate dynamism revealed by adenoviral hepatic overexpression of apolipoprotein M. Atherosclerosis. 2013.07; 229 (1): 102-109. ( PubMed , DOI )

  7. Hitoshi Ikeda, Kenichiro Enooku, Ryunosuke Ohkawa, Kazuhiko Koike, Yutaka Yatomi: Plasma lysophosphatidic acid levels and hepatocellular carcinoma. Hepatology. 2013.01; 57 (1): 417-418. ( PubMed , DOI )

  8. Hayakazu Sumida, Kazuhiro Nakamura, Keisuke Yanagida, Ryunosuke Ohkawa, Yoshihide Asano, Takafumi Kadono, Kunihiko Tamaki, Koji Igarashi, Junken Aoki, Shinichi Sato, Satoshi Ishii, Takao Shimizu, Yutaka Yatomi: Decrease in circulating autotaxin by oral administration of prednisolone. Clin. Chim. Acta. 2013.01; 415 74-80. ( PubMed , DOI )

  9. 11. 蔵野 信，大川 龍之介，池田 均，矢冨 裕: スフィンゴシン1-リン酸-基礎から臨床へ 臨床化学. 2013; 42 242-249.

  10. Yoshikazu Ono, Makoto Kurano, Ryunosuke Ohkawa, Hiromitsu Yokota, Koji Igarashi, Junken Aoki, Minoru Tozuka, Yutaka Yatomi: Sphingosine 1-phosphate release from platelets during clot formation: close correlation between platelet count and serum sphingosine 1-phosphate concentration. Lipids Health Dis. 2013; 12 20. ( PubMed , DOI )

  1. Tomotaka Dohi, Katsumi Miyauchi, Ryunosuke Ohkawa, Kazuhiro Nakamura, Shuta Thuboi, Manabu Ogita, Tadashi Miyazaki, Akihisa Nishino, Ken Yokoyama, Takeshi Kurata, Yutaka Yatomi, Hiroyuki Daida: Higher lipoprotein-associated phospholipase A2 levels are associated with coronary atherosclerosis documented by coronary angiography. Ann. Clin. Biochem.. 2012.11; 49 (Pt 6): 527-533. ( PubMed , DOI )

  2. Ryunosuke Ohkawa, Tatsuya Kishimoto, Makoto Kurano, Tomotaka Dohi, Katsumi Miyauchi, Hiroyuki Daida, Mika Nagasaki, Kansei Uno, Naoto Hayashi, Noboru Sakai, Naoto Matsuyama, Takahiro Nojiri, Kazuhiro Nakamura, Shigeo Okubo, Hiromitsu Yokota, Hitoshi Ikeda, Yutaka Yatomi: Development of an enzymatic assay for sphingomyelin with rapid and automatable performances: Analysis in healthy subjects and coronary heart disease patients. Clin. Biochem.. 2012.11; 45 (16-17): 1463-1470. ( PubMed , DOI )

  3. Kazuhiro Nakamura, Koji Igarashi, Ryunosuke Ohkawa, Hiromitsu Yokota, Akiko Masuda, Shunsuke Nakagawa, Tetsu Yano, Hitoshi Ikeda, Junken Aoki, Yutaka Yatomi: Serum autotaxin is not a useful biomarker for ovarian cancer. Lipids. 2012.09; 47 (9): 927-930. ( PubMed , DOI )

  4. Nobuharu Suzuki, Masaya Fukushi, Keisuke Kosaki, Andrew D Doyle, Susana de Vega, Keigo Yoshizaki, Chihiro Akazawa, Eri Arikawa-Hirasawa, Yoshihiko Yamada: Teneurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS. J Neurosci. 2012.08; 32 (34): 11586-11599. ( PubMed , DOI )

  5. Yoko Soroida, Ryunosuke Ohkawa, Hayato Nakagawa, Yumiko Satoh, Haruhiko Yoshida, Hiroto Kinoshita, Ryosuke Tateishi, Ryota Masuzaki, Kenichiro Enooku, Shuichiro Shiina, Takahisa Sato, Shuntaro Obi, Tadashi Hoshino, Ritsuko Nagatomo, Shigeo Okubo, Hiromitsu Yokota, Kazuhiko Koike, Yutaka Yatomi, Hitoshi Ikeda: Increased activity of serum mitochondrial isoenzyme of creatine kinase in hepatocellular carcinoma patients predominantly with recurrence. J. Hepatol.. 2012.08; 57 (2): 330-336. ( PubMed , DOI )

  6. Tomonori Sugiura, Yasuaki Dohi, Sumiyo Yamashita, Nobuyuki Ohte, Shiori Ito, Soichiro Iwaki, Yuji Hirowatari, Ryunosuke Ohkawa, Yuko Mishima, Yutaka Yatomi, Genjiro Kimura, Satoshi Fujii: Analytical evaluation of plasma serotonin and sphingosine 1-phosphate and their clinical assessment in early atherosclerosis. Coron. Artery Dis.. 2012.06; 23 (4): 234-238. ( PubMed , DOI )

  7. Muneaki Ishijima, Nobuharu Suzuki, Kentaro Hozumi, Tomoya Matsunobu, Keisuke Kosaki, Haruka Kaneko, John R Hassell, Eri Arikawa-Hirasawa, Yoshihiko Yamada: Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation. Matrix Biol. 2012.05; 31 (4): 234-245. ( PubMed , DOI )

  8. Tomotaka Dohi, Katsumi Miyauchi, Ryunosuke Ohkawa, Kazuhiro Nakamura, Tatsuya Kishimoto, Tadashi Miyazaki, Akihisa Nishino, Naohisa Nakajima, Kenji Yaginuma, Hiroshi Tamura, Takahiko Kojima, Ken Yokoyama, Takeshi Kurata, Kazunori Shimada, Yutaka Yatomi, Hiroyuki Daida: Increased circulating plasma lysophosphatidic acid in patients with acute coronary syndrome. Clin. Chim. Acta. 2012.01; 413 (1-2): 207-212. ( PubMed , DOI )

  1. Tomotaka Dohi, Katsumi Miyauchi, Shinya Okazaki, Takayuki Yokoyama, Ryunosuke Ohkawa, Kazuhiro Nakamura, Naotake Yanagisawa, Shuta Tsuboi, Manabu Ogita, Ken Yokoyama, Takeshi Kurata, Yutaka Yatomi, Hiroyuki Daida: Decreased circulating lipoprotein-associated phospholipase A2 levels are associated with coronary plaque regression in patients with acute coronary syndrome. Atherosclerosis. 2011.12; 219 (2): 907-912. ( PubMed , DOI )

  2. Akiko Masuda, Tomoyuki Fujii, Yuki Iwasawa, Kazuhiro Nakamura, Ryunosuke Ohkawa, Koji Igarashi, Shinichi Okudaira, Hitoshi Ikeda, Shiro Kozuma, Junken Aoki, Yutaka Yatomi: Serum autotaxin measurements in pregnant women: application for the differentiation of normal pregnancy and pregnancy-induced hypertension. Clin. Chim. Acta. 2011.10; 412 (21-22): 1944-1950. ( PubMed , DOI )

  3. Hayato Nakagawa, Hitoshi Ikeda, Kazuhiro Nakamura, Ryunosuke Ohkawa, Ryota Masuzaki, Ryosuke Tateishi, Haruhiko Yoshida, Naoko Watanabe, Kazuaki Tejima, Yukio Kume, Tomomi Iwai, Atsushi Suzuki, Tomoaki Tomiya, Yukiko Inoue, Takako Nishikawa, Natsuko Ohtomo, Yasushi Tanoue, Masao Omata, Koji Igarashi, Junken Aoki, Kazuhiko Koike, Yutaka Yatomi: Autotaxin as a novel serum marker of liver fibrosis. Clin. Chim. Acta. 2011.06; 412 (13-14): 1201-1206. ( PubMed , DOI )

  1. Kazuhiro Nakamura, Koji Igarashi, Ryunosuke Ohkawa, Naoya Saiki, Mika Nagasaki, Kansei Uno, Naoto Hayashi, Tetsuji Sawada, Kenichi Syukuya, Hiromitsu Yokota, Hiroyuki Arai, Hitoshi Ikeda, Junken Aoki, Yutaka Yatomi: A novel enzyme immunoassay for the determination of phosphatidylserine-specific phospholipase A(1) in human serum samples. Clin. Chim. Acta. 2010.08; 411 (15-16): 1090-1094. ( PubMed , DOI )

  2. Hitoshi Ikeda, Ryunosuke Ohkawa, Naoko Watanabe, Kazuhiro Nakamura, Yukio Kume, Hayato Nakagawa, Haruhiko Yoshida, Shigeo Okubo, Hiromitsu Yokota, Tomoaki Tomiya, Yukiko Inoue, Takako Nishikawa, Natsuko Ohtomo, Yasushi Tanoue, Kazuhiko Koike, Yutaka Yatomi: Plasma concentration of bioactive lipid mediator sphingosine 1-phosphate is reduced in patients with chronic hepatitis C. Clin. Chim. Acta. 2010.05; 411 (9-10): 765-770. ( PubMed , DOI )

  3. Xun Qi, Yasuo Okamoto, Tomomi Murakawa, Fei Wang, Osamu Oyama, Ryunosuke Ohkawa, Kazuaki Yoshioka, Wa Du, Naotoshi Sugimoto, Yutaka Yatomi, Noriko Takuwa, Yoh Takuwa: Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice. Eur. J. Pharmacol.. 2010.05; 634 (1-3): 121-131. ( PubMed , DOI )

  4. Nobuharu Suzuki, Kentaro Hozumi, Shunsuke Urushibata, Takashi Yoshimura, Yamato Kikkawa, Jessica D Gumerson, Daniel E Michele, Matthew P Hoffman, Yoshihiko Yamada, Motoyoshi Nomizu: Identification of alpha-dystroglycan binding sequences in the laminin alpha2 chain LG4-5 module. Matrix Biol.. 2010.03; 29 (2): 143-151. ( PubMed , DOI )

  5. Toshiyuki Imasawa, Hiroshi Kitamura, Ryunosuke Ohkawa, Yumiko Satoh, Akiko Miyashita, Yutaka Yatomi: Unbalanced expression of sphingosine 1-phosphate receptors in diabetic nephropathy. Exp. Toxicol. Pathol.. 2010.01; 62 (1): 53-60. ( PubMed , DOI )

  6. 西村 智，長崎 実佳，中村 和宏，大川 龍之介，田嶋 美智子，良永 千穂，宇野 漢成，真鍋 一郎，永井 良三，林 直人，矢冨 裕: 血清リン脂質・生合成系を用いた新規メタボリックシンドロームマーカーの探索 脂質生化学研究. 2010; 52 237-238.

  1. Harumasa Nakazawa, Hiroaki Ohnishi, Hitoshi Okazaki, Shiho Hashimoto, Hajime Hotta, Takashi Watanabe, Ryunosuke Ohkawa, Yutaka Yatomi, Kazunori Nakajima, Yasuhide Iwao, Shigeru Takamoto, Masaru Shimizu, Takehiko Iijima: Impact of fresh-frozen plasma from male-only donors versus mixed-sex donors on postoperative respiratory function in surgical patients: a prospective case-controlled study. Transfusion. 2009.11; 49 (11): 2434-2441. ( PubMed , DOI )

  2. Kazuhiro Nakamura, Ryunosuke Ohkawa, Shigeo Okubo, Hiromitsu Yokota, Hitoshi Ikeda, Yutaka Yatomi, Koji Igarashi, Kazufumi Ide, Tatsuya Kishimoto, Akiko Masuda, Tomotaka Yamamoto, Shoji Tsuji, Nobuhito Saito, Mineo Kurokawa, Shinichi Okudaira, Junken Aoki: Autotaxin enzyme immunoassay in human cerebrospinal fluid samples. Clin. Chim. Acta. 2009.07; 405 (1-2): 160-162. ( PubMed , DOI )

  3. Kentaro Hozumi, Nobuharu Suzuki, Yoshihiko Uchiyama, Fumihiko Katagiri, Yamato Kikkawa, Motoyoshi Nomizu: Chain-specific heparin-binding sequences in the laminin alpha chain LG45 modules. Biochemistry. 2009.06; 48 (23): 5375-5381. ( PubMed , DOI )

  4. Shu Takaki, Kozue Kato-Takagaki, Nobuharu Suzuki, Shinya Oishi, Yamato Kikkawa, Motoyoshi Nomizu: Cyclic peptide analogs of laminin active sequences enhance the biological activity. Adv. Exp. Med. Biol.. 2009; 611 297-298. ( PubMed )

  5. 西村 智，長崎 実佳，中村 和宏，大川 龍之介，田嶋 美智子，若林 香織，宇野 漢成，真鍋 一郎，永井 良三，林 直人，矢冨 裕: 血清リン脂質・生合成系の変化は加齢・慢性炎症に伴うメタボリックシンドロームの発症を規定する 脂質生化学研究. 2009; 51 298-299.

  1. Atsushi Kimura, Tsukasa Ohmori, Yuji Kashiwakura, Ryunosuke Ohkawa, Seiji Madoiwa, Jun Mimuro, Kuniko Shimazaki, Yuichi Hoshino, Yutaka Yatomi, Yoichi Sakata: Antagonism of sphingosine 1-phosphate receptor-2 enhances migration of neural progenitor cells toward an area of brain. Stroke. 2008.12; 39 (12): 3411-3417. ( PubMed , DOI )

  2. Akiko Masuda, Kazuhiro Nakamura, Koji Izutsu, Koji Igarashi, Ryunosuke Ohkawa, Masahiro Jona, Katsumi Higashi, Hiromitsu Yokota, Shinichi Okudaira, Tatsuya Kishimoto, Takuro Watanabe, Yukako Koike, Hitoshi Ikeda, Yasushi Kozai, Mineo Kurokawa, Junken Aoki, Yutaka Yatomi: Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma. Br. J. Haematol.. 2008.10; 143 (1): 60-70. ( PubMed , DOI )

  3. Shigemi Hosogaya, Yutaka Yatomi, Kazuhiro Nakamura, Ryunosuke Ohkawa, Shigeo Okubo, Hiromitsu Yokota, Masato Ohta, Hirokazu Yamazaki, Toru Koike, Yukio Ozaki: Measurement of plasma lysophosphatidic acid concentration in healthy subjects: strong correlation with lysophospholipase D activity. Ann. Clin. Biochem.. 2008.07; 45 (Pt 4): 364-368. ( PubMed , DOI )

  4. Ryunosuke Ohkawa, Kazuhiro Nakamura, Shigeo Okubo, Shigemi Hosogaya, Yukio Ozaki, Minoru Tozuka, Noriko Osima, Hiromitsu Yokota, Hitoshi Ikeda, Yutaka Yatomi: Plasma sphingosine-1-phosphate measurement in healthy subjects: close correlation with red blood cell parameters. Ann. Clin. Biochem.. 2008.07; 45 (Pt 4): 356-363. ( PubMed , DOI )

  5. Kazuhiro Nakamura, Koji Igarashi, Kazufumi Ide, Ryunosuke Ohkawa, Shigeo Okubo, Hiromitsu Yokota, Akiko Masuda, Noriko Oshima, Takumi Takeuchi, Masaomi Nangaku, Shinichi Okudaira, Hiroyuki Arai, Hitoshi Ikeda, Junken Aoki, Yutaka Yatomi: Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation. Clin. Chim. Acta. 2008.02; 388 (1-2): 51-58. ( PubMed , DOI )

  6. Kazuhiro Nakamura, Masaomi Nangaku, Ryunosuke Ohkawa, Shigeo Okubo, Hiromitsu Yokota, Hitoshi Ikeda, Junken Aoki, Yutaka Yatomi: Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome. Clin. Chem. Lab. Med.. 2008; 46 (1): 150-151. ( PubMed , DOI )

  1. Kazuhiro Nakamura, Takumi Takeuchi, Ryunosuke Ohkawa, Shigeo Okubo, Hiromitsu Yokota, Minoru Tozuka, Junken Aoki, Hiroyuki Arai, Hitoshi Ikeda, Noriko Ohshima, Tadaichi Kitamura, Yutaka Yatomi: Serum lysophospholipase D/autotaxin may be a new nutritional assessment marker: study on prostate cancer patients. Ann. Clin. Biochem.. 2007.11; 44 (Pt 6): 549-556. ( PubMed , DOI )

  2. Naoko Watanabe, Hitoshi Ikeda, Kazuhiro Nakamura, Ryunosuke Ohkawa, Yukio Kume, Tomoaki Tomiya, Kazuaki Tejima, Takako Nishikawa, Masahiro Arai, Mikio Yanase, Junken Aoki, Hiroyuki Arai, Masao Omata, Kenji Fujiwara, Yutaka Yatomi: Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity. Life Sci.. 2007.09; 81 (12): 1009-1015. ( PubMed , DOI )

  3. Kazuhiro Nakamura, Tatsuya Kishimoto, Ryunosuke Ohkawa, Shigeo Okubo, Minoru Tozuka, Hiromitsu Yokota, Hitoshi Ikeda, Noriko Ohshima, Koji Mizuno, Yutaka Yatomi: Suppression of lysophosphatidic acid and lysophosphatidylcholine formation in the plasma in vitro: proposal of a plasma sample preparation method for laboratory testing of these lipids. Anal. Biochem.. 2007.08; 367 (1): 20-27. ( PubMed , DOI )

  4. Naoko Watanabe, Hitoshi Ikeda, Kazuhiro Nakamura, Ryunosuke Ohkawa, Yukio Kume, Junken Aoki, Kotaro Hama, Shinichi Okudaira, Masayuki Tanaka, Tomoaki Tomiya, Mikio Yanase, Kazuaki Tejima, Takako Nishikawa, Masahiro Arai, Hiroyuki Arai, Masao Omata, Kenji Fujiwara, Yutaka Yatomi: Both plasma lysophosphatidic acid and serum autotaxin levels are increased in chronic hepatitis C. J. Clin. Gastroenterol.. 2007.07; 41 (6): 616-623. ( PubMed , DOI )

  5. Yumiko Satoh, Ryunosuke Ohkawa, Kazuhiro Nakamura, Katsumi Higashi, Makoto Kaneko, Hiromitsu Yokota, Junken Aoki, Hiroyuki Arai, Yasuhito Yuasa, Yutaka Yatomi: Lysophosphatidic acid protection against apoptosis in the human pre-B-cell line Nalm-6. Eur. J. Haematol.. 2007.06; 78 (6): 510-517. ( PubMed , DOI )

  6. Mayumi Mochizuki, Deborah Philp, Kentaro Hozumi, Nobuharu Suzuki, Yoshihiko Yamada, Hynda K Kleinman, Motoyoshi Nomizu: Angiogenic activity of syndecan-binding laminin peptide AG73 (RKRLQVQLSIRT). Arch. Biochem. Biophys.. 2007.03; 459 (2): 249-255. ( PubMed , DOI )

  7. Kozue Kato-Takagaki, Nobuharu Suzuki, Fumiharu Yokoyama, Shu Takaki, Koji Umezawa, Junichi Higo, Mayumi Mochizuki, Yamato Kikkawa, Shinya Oishi, Atsushi Utani, Motoyoshi Nomizu: Cyclic peptide analysis of the biologically active loop region in the laminin alpha3 chain LG4 module demonstrates the importance of peptide conformation on biological activity. Biochemistry. 2007.02; 46 (7): 1952-1960. ( PubMed , DOI )

  8. Kazuhiro Nakamura, Ryunosuke Ohkawa, Shigeo Okubo, Minoru Tozuka, Mitsumasa Okada, Shinya Aoki, Junken Aoki, Hiroyuki Arai, Hitoshi Ikeda, Yutaka Yatomi: Measurement of lysophospholipase D/autotaxin activity in human serum samples. Clin. Biochem.. 2007.02; 40 (3-4): 274-277. ( PubMed , DOI )

  9. Atsushi Kimura, Tsukasa Ohmori, Ryunosuke Ohkawa, Seiji Madoiwa, Jun Mimuro, Takashi Murakami, Eiji Kobayashi, Yuichi Hoshino, Yutaka Yatomi, Yoichi Sakata: Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury. Stem Cells. 2007.01; 25 (1): 115-124. ( PubMed , DOI )

  1. Ryunosuke Ohkawa, Nobuo Hisano, Kazuhiro Nakamura, Shigeo Okubo, Hiromitsu Yokota, Yutaka Yatomi: Lysophospholipase D activity exists in the urine to catalyse the formation of lysophosphatidic acid. Nephrol. Dial. Transplant.. 2006.12; 21 (12): 3612-3613. ( PubMed , DOI )

  2. Kentaro Hozumi, Nobuharu Suzuki, Peter K Nielsen, Motoyoshi Nomizu, Yoshihiko Yamada: Laminin alpha1 chain LG4 module promotes cell attachment through syndecans and cell spreading through integrin alpha2beta1. J. Biol. Chem.. 2006.10; 281 (43): 32929-32940. ( PubMed , DOI )

  3. Masayuki Tanaka, Shinichi Okudaira, Yasuhiro Kishi, Ryunosuke Ohkawa, Sachiko Iseki, Masato Ota, Sumihare Noji, Yutaka Yatomi, Junken Aoki, Hiroyuki Arai: Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid. J. Biol. Chem.. 2006.09; 281 (35): 25822-25830. ( PubMed , DOI )

  1. Ryunosuke Ohkawa, Yuji Hirowatari, Kazuhiro Nakamura, Shigeo Ohkubo, Hitoshi Ikeda, Mitsumasa Okada, Minoru Tozuka, Kazuhiko Nakahara, Yutaka Yatomi: Platelet release of beta-thromboglobulin and platelet factor 4 and serotonin in plasma samples. Clin. Biochem.. 2005.11; 38 (11): 1023-1026. ( PubMed , DOI )

  2. Fumiharu Yokoyama, Nobuharu Suzuki, Yuichi Kadoya, Atsushi Utani, Hiroko Nakatsuka, Norio Nishi, Masahiro Haruki, Hynda K Kleinman, Motoyoshi Nomizu: Bifunctional peptides derived from homologous loop regions in the laminin alpha chain LG4 modules interact with both alpha 2 beta 1 integrin and syndecan-2. Biochemistry. 2005.07; 44 (28): 9581-9589. ( PubMed , DOI )

  3. Naoki Ichikawa, Shingo Kasai, Nobuharu Suzuki, Norio Nishi, Shinya Oishi, Nobutaka Fujii, Yuichi Kadoya, Kozo Hatori, Yoshikuni Mizuno, Motoyoshi Nomizu, Eri Arikawa-Hirasawa: Identification of neurite outgrowth active sites on the laminin alpha4 chain G domain. Biochemistry. 2005.04; 44 (15): 5755-5762. ( PubMed , DOI )

  4. Akane Kondo, Junko Inagaki, Kazuko Kobayashi, Hideo Tsukamoto, Daisuke Yamamoto, Mikiya Nakatsuka, Nobuharu Suzuki, Motoyoshi Nomizu, Satoshi Amano, Hidehiko Matsubayashi, Tatsuji Yasuda, Luis R Lopez, Yehuda Shoenfeld, Tsunehisa Makino, Eiji Matsuura: Characterization of a murine anti-laminin-1 monoclonal antibody (AK8) produced by immunization with mouse-derived laminin-1. Clin. Dev. Immunol.. 2005.03; 12 (1): 67-73. ( PubMed )

  5. Yutaka Momota, Nobuharu Suzuki, Yoshitoshi Kasuya, Takashi Kobayashi, Masako Mizoguchi, Fumiharu Yokoyama, Motoyoshi Nomizu, Hiroshi Shinkai, Toshiroh Iwasaki, Atsushi Utani: Laminin alpha3 LG4 module induces keratinocyte migration: involvement of matrix metalloproteinase-9. J. Recept. Signal Transduct. Res.. 2005; 25 (1): 1-17. ( PubMed , DOI )

  6. Nobuharu Suzuki, Fumiharu Yokoyama, Motoyoshi Nomizu: Functional sites in the laminin alpha chains. Connect. Tissue Res.. 2005; 46 (3): 142-152. ( PubMed , DOI )

  1. Fumiharu Yokoyama, Nobuharu Suzuki, Masahiro Haruki, Norio Nishi, Shinya Oishi, Nobutaka Fujii, Atsushi Utani, Hynda K Kleinman, Motoyoshi Nomizu: Cyclic peptides from the loop region of the laminin alpha 4 chain LG4 module show enhanced biological activity over linear peptides. Biochemistry. 2004.10; 43 (42): 13590-13597. ( PubMed , DOI )

  2. Hiroshi Matsuura, Yutaka Momota, Kaoru Murata, Hironori Matsushima, Nobuharu Suzuki, Motoyoshi Nomizu, Hiroshi Shinkai, Atsushi Utani: Localization of the laminin alpha4 chain in the skin and identification of a heparin-dependent cell adhesion site within the laminin alpha4 chain C-terminal LG4 module. J. Invest. Dermatol.. 2004.03; 122 (3): 614-620. ( PubMed , DOI )

  1. Nobuharu Suzuki, Naoki Ichikawa, Shingo Kasai, Masanori Yamada, Norio Nishi, Hiroshi Morioka, Hironobu Yamashita, Yasuo Kitagawa, Atsushi Utani, Matthew P Hoffman, Motoyoshi Nomizu: Syndecan binding sites in the laminin alpha1 chain G domain. Biochemistry. 2003.11; 42 (43): 12625-12633. ( PubMed , DOI )

  2. Nobuharu Suzuki, Hiroko Nakatsuka, Mayumi Mochizuki, Norio Nishi, Yuichi Kadoya, Atsushi Utani, Shinya Oishi, Nobutaka Fujii, Hynda K Kleinman, Motoyoshi Nomizu: Biological activities of homologous loop regions in the laminin alpha chain G domains. J. Biol. Chem.. 2003.11; 278 (46): 45697-45705. ( PubMed , DOI )

  3. Atsushi Utani, Yutaka Momota, Hideharu Endo, Yoshitoshi Kasuya, Konrad Beck, Nobuharu Suzuki, Motoyoshi Nomizu, Hiroshi Shinkai: Laminin alpha 3 LG4 module induces matrix metalloproteinase-1 through mitogen-activated protein kinase signaling. J. Biol. Chem.. 2003.09; 278 (36): 34483-34490. ( PubMed , DOI )

  4. 久米 幸夫，日暮 公野，大川 龍之介，名倉 豊，大久保 滋夫，曽根 伸治，眞重 文子，福本 誠二，高橋 孝喜，中原 一彦: 梅毒関連項目の自動化(その２) Prestige24iを用いた基礎的検討(梅毒脂質抗体) 日本臨床検査自動化学会会誌. 2003.09; 28 (4): 413.

  5. 久米 幸夫，日暮 公野，大川 龍之介，名倉 豊，大久保 滋夫，曽根 伸治，眞重 文子，福本 誠二，高橋 孝喜，中原 一彦: 梅毒関連項目の自動化(その３) Prestige24iを用いた基礎的検討(抗TP抗体) 日本臨床検査自動化学会会誌. 2003.09; 28 (4): 414.

  6. Junko Inagaki, Mayumi Sugiura-Ogasawara, Motoyoshi Nomizu, Mikiya Nakatsuka, Katsuo Ikuta, Nobuharu Suzuki, Keiko Kaihara, Kazuko Kobayashi, Tatsuji Yasuda, Yehuda Shoenfeld, Koji Aoki, Eiji Matsuura: An association of IgG anti-laminin-1 autoantibodies with endometriosis in infertile patients. Hum. Reprod.. 2003.03; 18 (3): 544-549. ( PubMed )

  1. Ikuko Okazaki, Nobuharu Suzuki, Norio Nishi, Atsushi Utani, Hiroshi Matsuura, Hiroshi Shinkai, Hironobu Yamashita, Yasuo Kitagawa, Motoyoshi Nomizu: Identification of biologically active sequences in the laminin alpha 4 chain G domain. J. Biol. Chem.. 2002.10; 277 (40): 37070-37078. ( PubMed , DOI )

  2. Kozue Kato, Atsushi Utani, Nobuharu Suzuki, Mayumi Mochizuki, Masanori Yamada, Norio Nishi, Hiroshi Matsuura, Hiroshi Shinkai, Motoyoshi Nomizu: Identification of neurite outgrowth promoting sites on the laminin alpha 3 chain G domain. Biochemistry. 2002.09; 41 (35): 10747-10753. ( PubMed )

  1. M Nomizu, F Yokoyama, N Suzuki, I Okazaki, N Nishi, M L Ponce, H K Kleinman, Y Yamamoto, S Nakagawa, T Mayumi: Identification of homologous biologically active sites on the N-terminal domain of laminin alpha chains. Biochemistry. 2001.12; 40 (50): 15310-15317. ( PubMed )

  1. Binri Sasaki, Reina Ono, Momona Yamada, Nanako Yamada, Nobuharu Suzuki: The regulatory mechanism of oligodendrocyte development and differentiation by extracellular matrix molecules Journal of Japanese Biochemical Society. 2024.04; 96 (2): 296-300.

  1. Chikako Hayashi, Momona Yamada, Miho Iwase, Nobuharu Suzuki: The regulation of axonal homeostasis by myelin: From studies with genetically engineered mice 2021.03; 36 (4): 353-357.

  1. Nobuharu Suzuki, Miho Iwase, Momona Yamada: The mechanism of axon maintenance by myelin in the central nervous system 2020.12; 9 (2): 103-109.

  1. Chikako Hayashi, Nobuharu Suzuki: Morphological and Functional Diversity of Oligodendrocytes in the Central Nervous System Journal of Japanese Biochemical Society. 2019.10; 91 (5): 701-705.

  1. Takahiro Nojiri, Akiko Masuda, Ryunosuke Ohkawa, Kiyoko Koido, Hironori Shimosaka, Shigeo Okubo, Hiromitsu Yokota, Makoto Kurano, Yasuhito Nannya, Hitoshi Ikeda, Mineo Kurokawa, Yutaka Yatomi: Difference in measurements of erythrocyte sedimentation rate obtained using two devices of the same model in a patient with marked leukocytosis Rinsho Byori. 2014.07; 62 (7): 664-667. ( PubMed )

  1. Ryunosuke Ohkawa, Makoto Kurano, Kazuhiro Nakamura, Shigeo Okubo, Hiromitsu Yokota, Hitoshi Ikeda, Yutaka Yatomi: Sphingolipids, possible biomarkers for atherosclerotic disorders Rinsho Byori. 2013.09; 61 (9): 795-802. ( PubMed )

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