Department of Clinical and Diagnostic Laboratory Science

114  articles.  
* There may be some overlapped articles listed due to the difference of format.

  1. Miyako Murakawa, Mina Nakagawa, Hisaaki Nishimura, Shun Kaneko, Masato Miyoshi, Fukiko Kawai-Kitahata, Sayuri Nitta, Jun Tsuchiya, Taro Shimizu, Keiya Watakabe, Tomohiro Mochida, Kento Inada, Yasuhiro Iizuka, Hideki Sakai, Yuki Sakurai, Ayako Sato, Seishin Azuma, Takahiro Kawamura, Chiaki Maeyashiki, Masayuki Kurosaki, Fumihiko Kusano, Hideki Watanabe, Hitoshi Kurata, Yuko Karakama, Takeo Fujiwara, Yuki Nagata, Toshihiro Tanaka, Sei Kakinuma, Ryuichi Okamoto, Yasuhiro Asahina: High serum gamma-glutamyltransferase level after hepatitis C virus elimination is a risk factor for the development of hepatocellular carcinoma. Hepatol Res. 2024.12; 54 (12): 1128-1138. ( PubMed , DOI )

  2. Jun Tsuchiya, Masato Miyoshi, Sei Kakinuma, Fukiko Kawai-Kitahata, Akihide Kamiya, Taro Shimizu, Ayako Sato, Keiya Watakabe, Tomohiro Mochida, Kento Inada, Rion Kamimae, Shun Kaneko, Miyako Murakawa, Sayuri Nitta, Mina Nakagawa, Mamoru Watanabe, Yasuhiro Asahina, Ryuichi Okamoto: Hepatitis B Virus-KMT2B Integration Drives Hepatic Oncogenic Processes in a Human Gene-edited Induced Pluripotent Stem Cells-derived Model. Cell Mol Gastroenterol Hepatol. 2024.10; Online ahead of print 101422. ( PubMed , DOI )

  3. Watakabe K, Miyoshi M, Kakinuma S, Sato A, Tsuchiya J, Shimizu T, Mochida T, Inada K, Kaneko S, Kawai-Kitahata F, Murakawa M, Nitta S, Nakagawa M, Oshima S, Watanabe M, Ma A, Asahina Y, Okamoto R: A20 in hepatic stellate cells suppresses chronic hepatitis by inhibiting DCLK1-JNK pathway-dependent chemokines. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2024.07; 38 (13): e23757. ( PubMed , DOI )

  4. Shun Kaneko, Yasuhiro Asahina, Miyako Murakawa, Shunsuke Ueyama, Chiaki Maeyashiki, Hideki Watanabe, Akiko Kusano-Kitazume, Ayako Sato, Kozue Uchidate, Takehito Asakawa, Sho Watanabe, Yasuhiro Iizuka, Isamu Shibata, Shinya Oooka, Yuko Karakama, Takashi Fujii, Taro Watabe, Keiichi Akahoshi, Minoru Tanabe, Kento Inada, Tomohiro Mochida, Keiya Watakabe, Taro Shimizu, Jun Tsuchiya, Masato Miyoshi, Fukiko Kitahata-Kawai, Sayuri Nitta, Mina Nakagawa, Sei Kakinuma, Ryuichi Okamoto, : Prognostic significance of C-reactive protein in unresectable hepatocellular carcinoma treated with atezolizumab and bevacizumab. Hepatol Res. 2024.06; 54 (6): 562-574. ( PubMed , DOI )

  5. Yamaguchi J, Takigawa M, Goya M, Martin CA, Negishi M, Yamamoto T, Ikenouchi T, Goto K, Shigeta T, Kawamura I, Nishimura T, Takamiya T, Tao S, Miyazaki S, Sasano T: Impact of contact force on the lesion characteristics of very high-power short-duration ablation using a QDOT-MICRO catheter. Journal of arrhythmia. 2024.04; 40 (2): 247-255. ( PubMed , DOI )

  6. Kaneko S, Asahina Y, Murakawa M, Azuma S, Inada K, Mochida T, Watakabe K, Shimizu T, Tsuchiya J, Miyoshi M, Kawai-Kitahata F, Nitta S, Takahashi M, Fujioka T, Kishino M, Anzai T, Kakinuma S, Nakagawa M, Okamoto R: Analysis of prognosis and background liver disease in non-advanced hepatocellular carcinoma in two decades. PLoS ONE. 2024.03; 19 (3): e0297882. ( PubMed , DOI )

  7. Yamamoto T, Takigawa M, Shigeta T, Martin CA, Yamaguchi J, Amemiya M, Ikenouchi T, Negishi M, Kawamura I, Goto K, Nishimura T, Takamiya T, Tao S, Miyazaki S, Goya M, Sasano T: Effect of reference electrode on intracardiac electrograms: Close indifferent electrode vs Wilson central terminal. Heart rhythm. 2024.03; ( PubMed , DOI )

  1. Yamaguchi J, Takigawa M, Goya M, Yamamoto T, Ikenouchi T, Iwakawa H, Negishi M, Goto K, Shigeta T, Nishimura T, Takamiya T, Tao S, Miyazaki S, Sasano T: Safety verification of a novel irrigation catheter with flexible tip of laser-cut kerfs and contact force sensor. Pacing and clinical electrophysiology : PACE. 2023.12; 46 (12): 1536-1545. ( PubMed , DOI )

  2. Ikenouchi T, Takigawa M, Goya M, Yamaguchi J, Martin CA, Yamamoto T, Negishi M, Kawamura I, Goto K, Shigeta T, Nishimura T, Takamiya T, Tao S, Miyazaki S, Sasano T: The effect of half-normal saline irrigation on lesion characteristics in temperature-flow-controlled ablation. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing. 2023.11; ( PubMed , DOI )

  3. Iwakawa H, Takigawa M, Yamaguchi J, Martin CA, Goya M, Yamamoto T, Amemiya M, Ikenouchi T, Negishi M, Kawamura I, Goto K, Shigeta T, Nishimura T, Takamiya T, Tao S, Miyazaki S, Watanabe H, Sasano T: Superiority of the Combination of Input and Output Parameters to the Single Parameter for Lesion Size Estimation. Circulation journal : official journal of the Japanese Circulation Society. 2023.11; 87 (12): 1757-1764. ( PubMed , DOI )

  4. Takigawa M, Yamamoto T, Amemiya M, Martin CA, Ikenouchi T, Yamaguchi J, Negishi M, Goto K, Shigeta T, Nishimura T, Tao S, Miyazaki S, Goya M, Sasano T: Impact of baseline pool impedance on lesion metrics and steam pops in catheter ablation. Journal of cardiovascular electrophysiology. 2023.06; 34 (8): 1671-1680. ( PubMed , DOI )

  5. Mina Nakagawa, Yasuhiro Asahina, Sei Kakinuma, Ryuichi Okamoto: Impact of eradication of hepatitis C virus on liver-related and -unrelated diseases: morbidity and mortality of chronic hepatitis C after SVR. J Gastroenterol. 2023.04; 58 (4): 299-310. ( PubMed , DOI )

  6. Mina Nakagawa, Yasuhiro Asahina, Sei Kakinuma, Ryuichi Okamoto: Correction: Impact of eradication of hepatitis C virus on liver-related and -unrelated diseases: morbidity and mortality of chronic hepatitis C after SVR. J Gastroenterol. 2023.04; 58 (4): 311-312. ( PubMed , DOI )

  7. Ikenouchi T, Takigawa M, Goya M, Martin CA, Yamamoto T, Yamaguchi J, Goto K, Shigeta T, Nishimura T, Tao S, Miyazaki S, Sasano T: Comparison of lesion characteristics using temperature-flow-controlled versus conventional power-controlled ablation with fixed ablation index. Journal of cardiovascular electrophysiology. 2023.03; 34 (4): 908-917. ( PubMed , DOI )

  8. Yamaguchi J, Takigawa M, Goya M, Martin CA, Yamamoto T, Ikenouchi T, Shigeta T, Nishimura T, Tao S, Miyazaki S, Sasano T: Comparison of Three Different Approaches to Very High-power Short-duration Ablation using the QDOT-MICRO Catheter. Journal of cardiovascular electrophysiology. 2023.02; 34 (4): 888-897. ( PubMed , DOI )

  9. Kaneko S, Asahina Y, Nakagawa M, Murakawa M, Miyazaki Y, Asakage T, Fukuda S, Namiki T, Kano Y, Nagata M, Tsuchiya J, Miyoshi M, Kitahata-Kawai F, Nitta S, Itsui Y, Kakinuma S, Okamoto R: Factors associated with liver injury and prognosis in advanced cancer patients treated with immune checkpoint inhibitors. Hepatology research : the official journal of the Japan Society of Hepatology. 2023.01; 53 (5): 450-459. ( PubMed , DOI )

  1. Takahashi J, Mizutani T, Sugihara HY, Nagata S, Kato S, Hiraguri Y, Takeoka S, Tsuchiya M, Kuno R, Kakinuma S, Watanabe M, Okamoto R: Suspension culture in a rotating bioreactor for efficient generation of human intestinal organoids. Cell Reports Methods. 2022.11; 2 (11): 100337. ( PubMed , DOI )

  2. Yamaguchi J, Takigawa M, Goya M, Martin C, Amemiya M, Yamamoto T, Nishimura T, Nakamura R, Shirai Y, Tao S, Miyazaki S, Takahashi Y, Sasano T: Impact of tip design and thermocouple location on the efficacy and safety of radiofrequency application. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing. 2022.04; 66 (4): 885-896. ( PubMed , DOI )

  3. Yamaguchi J, Chiba R, Komuro H, Ihara K, Nozaki K, Nagai A, Furukawa T, Sasano T: Local Injection of Hydroxyapatite Electret Ameliorated Infarct Size After Myocardial Infarction. Circulation reports. 2022.01; 4 (1): 38-47. ( PubMed , DOI )

  1. Yamaguchi J, Takigawa M, Tao S, Takahashi Y, Goya M, Sasano T: Successful Substrate Ablation for Ventricular Fibrillation in a Patient With Nonischemic Cardiomyopathy. JACC. Case reports. 2021.07; 3 (8): 1091-1096. ( PubMed , DOI )

  1. Takigawa M, Goya M, Yamaguchi J, Shirai Y, Martin CA, Sasano T: Life-threatening junctional ectopic tachycardia storm after injury around the atrioventricular-node successfully treated by mini-pulse corticosteroid therapy. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2020.10; 23 (3): 430. ( PubMed , DOI )

  2. Yamaguchi Junji, Takahashi Yoshihide, Yamamoto Tasuku, Amemiya Miki, Sekigawa Masahiro, Shirai Yasuhiro, Tao Susumu, Hayashi Tatsuya, Yagishita Atsuhiko, Takigawa Masateru, Goya Masahiko, Sasano Tetsuo: Clinical outcome of pulmonary vein isolation alone ablation strategy using VISITAG SURPOINT in nonparoxysmal atrial fibrillation JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY. 2020.10; 31 (10): 2592-2599. ( PubMed , DOI )

  3. Takigawa M, Goya M, Yamaguchi J, Shirai Y, Martin CA, Sasano T: Perimitral flutter with a long epicardial bypass tract successfully treated by selective ethanol infusion to a branch of the vein of Marshall. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2020.09; 22 (12): 1787. ( PubMed , DOI )

  4. Mina Nakagawa, Nobutoshi Nawa, Eiko Takeichi, Taro Shimizu, Jun Tsuchiya, Ayako Sato, Masato Miyoshi, Fukiko Kawai-Kitahata, Miyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Takeo Fujiwara, Mamoru Watanabe, Yujiro Tanaka, Yasuhiro Asahina: Mac-2 binding protein glycosylation isomer as a novel predictive biomarker for patient survival after hepatitis C virus eradication by DAAs. J Gastroenterol. 2020.08; 55 990-999. ( PubMed , DOI )

  5. Yamamoto T, Takahashi Y, Yamaguchi J, Sekigawa M, Shirai Y, Tao S, Hayashi T, Takigawa M, Goya M, Sasano T: Pulmonary vein narrowing after visually guided laser balloon ablation: Occurrence and clinical correlates. Journal of cardiovascular electrophysiology. 2020.05; ( PubMed , DOI )

  6. Sayuri Nitta, Kazuaki Takahashi, Fukiko Kawai-Kitahata, Jun Tsuchiya, Ayako Sato, Masato Miyoshi, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Sei Kakinuma, Mamoru Watanabe, Yasuhiro Asahina: Time course alterations of virus sequences and immunoglobulin titers in a chronic hepatitis E patient. Hepatol Res. 2020.04; 50 (4): 524-531. ( PubMed , DOI )

  7. Takahashi Y, Yamammoto T, Sekigawa M, Yamaguchi J, Shirai Y, Tao S, Hayashi T, Takigawa M, Goya M, Sasano T: Mapping After Pulmonary Vein Isolation in Persistent Atrial Fibrillation: Insights into the Role of Focal and Rotational Activation during Atrial Fibrillation. Circulation. Arrhythmia and electrophysiology. 2020.04; ( PubMed , DOI )

  8. Ayako Sato, Sei Kakinuma, Masato Miyoshi, Akihide Kamiya, Tomoyuki Tsunoda, Shun Kaneko, Jun Tsuchiya, Taro Shimizu, Eiko Takeichi, Sayuri Nitta, Fukiko Kawai-Kitahata, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Naohiko Koshikawa, Motoharu Seiki, Hiromitsu Nakauchi, Yasuhiro Asahina, Mamoru Watanabe: Vasoactive intestinal peptide derived from liver mesenchymal cells mediates tight junction assembly in mouse intrahepatic bile ducts. Hepatol Commun. 2020.02; 4 (2): 235-254. ( PubMed , DOI )

  9. Sagawa Yuichiro, Nagata Yasutoshi, Yamaguchi Tetsuo, Mitsui Kentaro, Nagamine Tatsuhiro, Yamaguchi Junji, Hijikata Sadahiro, Watanabe Keita, Masuda Ryo, Miyazaki Ryoichi, Kaneko Masakazu, Miwa Naoyuki, Sekigawa Masahiro, Hara Nobuhiro, Nozato Toshihiro, Ashikaga Takashi, Goya Masahiko, Sasano Tetsuo, Hirao Kenzo: Long-Term Performance of Right Ventricular Implantable Cardioverter-Defibrillator Leads in Arrhythmogenic Right Ventricular Cardiomyopathy and Hypertrophic Cardiomyopathy INTERNATIONAL HEART JOURNAL. 2020.01; 61 (1): 39-45. ( PubMed , DOI )

  1. Fukiko Kawai-Kitahata, Yasuhiro Asahina, Shun Kaneko, Jun Tsuchiya, Ayako Sato, Masato Miyoshi, Tomoyuki Tsunoda, Emi Inoue-Shinomiya, Miyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Sei Kakinuma, Minoru Tanabe, Emiko Sugawara, Akira Takemoto, Hidenori Ojima, Michiie Sakamoto, Masaru Muraoka, Shinichi Takano, Shinya Maekawa, Nobuyuki Enomoto, Mamoru Watanabe: Comprehensive genetic analysis of cholangiolocellular carcinoma with a coexistent hepatocellular carcinoma-like area and metachronous hepatocellular carcinoma. Hepatol Res. 2019.12; 49 (12): 1466-1474. ( PubMed , DOI )

  2. Yamaguchi T, Nozato T, Miwa N, Sagawa Y, Watanabe K, Nagata Y, Miyazaki R, Mitsui K, Nagase M, Nagamine T, Yamaguchi J, Masuda R, Kaneko M, Hara N, Ashikaga T: Impact of the preprocedural nutrition status on the clinical outcomes of patients after pacemaker implantation for bradycardia. Journal of cardiology. 2019.09; 74 (3): 284-289. ( PubMed , DOI )

  3. Tomoyuki Tsunoda, Sei Kakinuma, Masato Miyoshi, Akihide Kamiya, Shun Kaneko, Ayako Sato, Jun Tsuchiya, Sayuri Nitta, Fukiko Kawai-Kitahata, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Tsuyoshi Sogo, Haruki Komatsu, Ryutaro Mukouchi, Ayano Inui, Tomoo Fujisawa, Hiromitsu Nakauchi, Yasuhiro Asahina, Mamoru Watanabe: Loss of fibrocystin promotes interleukin-8-dependent proliferation and CTGF production of biliary epithelium. J. Hepatol.. 2019.07; 71 (1): 143-152. ( PubMed , DOI )

  4. Junji Yamaguchi, Yasutoshi Nagata, Yasuteru Yamauchi, Kenzo Hirao: New implications for the recurrence mechanism of an upper septal ventricular tachycardia: a case report. Eur Heart J Case Rep. 2019.06; 3 (2): ( PubMed , DOI )

  5. Sei Kakinuma, Mamoru Watanabe: Analysis of the mechanism underlying liver diseases using human induced pluripotent stem cells. Immunol Med. 2019.06; 42 (2): 71-78. ( PubMed , DOI )

  6. Emi Inoue-Shinomiya, Miyako Murakawa, Yasuhiro Asahina, Mina Nakagawa, Jun Tsuchiya, Ayako Sato, Tomoyuki Tsunoda, Masato Miyoshi, Sayuri Nitta, Fukiko Kawai-Kitahata, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Kazumoto Murata, Masashi Mizokami, Mamoru Watanabe: Association of serum interferon-λ3 levels with hepatocarcinogenesis in chronic hepatitis C patients treated with direct-acting antiviral agents. Hepatol Res. 2019.05; 49 (5): 500-511. ( ichushi )

  7. Emi Inoue-Shinomiya, Miyako Murakawa, Yasuhiro Asahina, Mina Nakagawa, Jun Tsuchiya, Ayako Sato, Tomoyuki Tsunoda, Masato Miyoshi, Sayuri Nitta, Fukiko Kawai-Kitahata, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Kazumoto Murata, Masashi Mizokami, Mamoru Watanabe: Association of serum interferon-λ3 levels with hepatocarcinogenesis in chronic hepatitis C patients treated with direct-acting antiviral agents. Hepatol. Res.. 2019.05; 49 (5): 500-511. ( PubMed , DOI )

  8. Sayuri Nitta, Yasuhiro Asahina, Takanobu Kato, Jun Tsuchiya, Emi Inoue-Shinomiya, Ayako Sato, Tomoyuki Tsunoda, Masato Miyoshi, Fukiko Kawai-Kitahata, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Sei Kakinuma, Hayato Hikita, Tetsuo Takehara, Mamoru Watanabe: Impact of novel NS5A resistance-associated substitutions of hepatitis C virus detected in treatment-experienced patients. Sci Rep. 2019.04; 9 (1): 5722. ( PubMed , DOI )

  9. Masato Miyoshi, Sei Kakinuma, Akihide Kamiya, Tomoyuki Tsunoda, Jun Tsuchiya, Ayako Sato, Shun Kaneko, Sayuri Nitta, Fukiko Kawai-Kitahata, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Hiromitsu Nakauchi, Yasuhiro Asahina, Mamoru Watanabe: LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells. Sci Rep. 2019.02; 9 (1): 2072. ( PubMed , DOI )

  10. Seishin Azuma, Yasuhiro Asahina, Sei Kakinuma, Keiko Azuma, Masato Miyoshi, Emi Inoue, Tomoyuki Tsunoda, Ayako Sato, Shun Kaneko, Hiroko Nagata, Fukiko Kawai-Kitahata, Miyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Makoto Tomita, Mina Nakagawa, Mamoru Watanabe: Diabetic Retinopathy as a Risk Factor Associated with the Development of Hepatocellular Carcinoma in Nonalcoholic Fatty Liver Disease. [Epub ahead of print] Dig Dis. 2019.01; 1-8. ( PubMed , DOI )

  11. Sei Kakinuma, Akihide Kamiya: A rodent model for cell transplantation of hepatic progenitor cells. Methods Mol Biol. 2019; 1905 211-219. ( PubMed , DOI )

  1. Inaba O, Yamauchi Y, Sekigawa M, Miwa N, Yamaguchi J, Nagata Y, Obayashi T, Miyamoto T, Kamata T, Isobe M, Goya M, Hirao K: Atrial fibrillation type matters: greater infarct volume and worse neurological defects seen in acute cardiogenic cerebral embolism due to persistent or permanent rather than paroxysmal atrial fibrillation. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2018.10; 20 (10): 1591-1597. ( PubMed , DOI )

  2. Yamaguchi T, Miyamoto T, Sekigawa M, Watanabe K, Hijikata S, Yamaguchi J, Iwai T, Sagawa Y, Miyazaki R, Masuda R, Miwa N, Hara N, Nagata Y, Obayashi T, Nozato T: Early Transfer of Patients with Acute Heart Failure from a Core Hospital to Collaborating Hospitals and Their Prognoses. International heart journal. 2018.09; 59 (5): 1026-1033. ( PubMed , DOI )

  3. Sagawa Y, Nagata Y, Yamaguchi T, Iwai T, Yamaguchi J, Hijikata S, Watanabe K, Masuda R, Miyazaki R, Miwa N, Sekigawa M, Hara N, Nozato T, Hirao K: Comparison of direct oral anticoagulants and warfarin regarding midterm adverse events in patients with atrial fibrillation undergoing catheter ablation. Journal of arrhythmia. 2018.08; 34 (4): 428-434. ( PubMed , DOI )

  4. Hijikata S, Miyamoto T, Yamaguchi T, Yamaguchi J, Iwai T, Watanabe K, Sagawa Y, Masuda R, Miyazaki R, Miwa N, Hara N, Nagata Y, Nozato T: Hemorrhagic shock due to branch injury of the left internal thoracic artery two days after pericardiocentesis. Journal of cardiology cases. 2018.07; 18 (1): 5-8. ( PubMed , DOI )

  5. Inaba O, Nagata Y, Sekigawa M, Miwa N, Yamaguchi J, Miyamoto T, Goya M, Hirao K: Impact of impedance decrease during radiofrequency current application for atrial fibrillation ablation on myocardial lesion and gap formation. Journal of arrhythmia. 2018.06; 34 (3): 247-253. ( PubMed , DOI )

  6. Yamaguchi T, Terashima M, Takamura C, Sakurai H, Ooishi K, Yoshizaki T, Yamaguchi J, Hijikata S, Iwai T, Sagawa Y, Watanabe K, Miyazaki R, Masuda R, Miwa N, Sekigawa M, Hara N, Nagata Y, Miyamoto T, Obayashi T, Nozato T: Cardiac Magnetic Resonance Imaging of Very Late Intrapericardial Hematoma 8 Years after Coronary Artery Bypass Grafting. Internal medicine (Tokyo, Japan). 2018.04; 57 (7): 975-978. ( PubMed , DOI )

  7. Yamaguchi T, Kitai T, Miyamoto T, Kagiyama N, Okumura T, Kida K, Oishi S, Akiyama E, Suzuki S, Yamamoto M, Yamaguchi J, Iwai T, Hijikata S, Masuda R, Miyazaki R, Hara N, Nagata Y, Nozato T, Matsue Y: Effect of Optimizing Guideline-Directed Medical Therapy Before Discharge on Mortality and Heart Failure Readmission in Patients Hospitalized With Heart Failure With Reduced Ejection Fraction. The American journal of cardiology. 2018.04; 121 (8): 969-974. ( PubMed , DOI )

  8. Hara N, Miyamoto T, Yamaguchi J, Iwai T, Hijikata S, Watanabe K, Sagawa Y, Masuda R, Miyazaki R, Miwa N, Sekigawa M, Yamaguchi T, Nagata Y, Nozato T, Kobayashi O, Umezawa S, Obayashi T: Treatment Outcomes of Anticoagulant Therapy and Temporary Inferior Vena Cava Filter Implantation for Pregnancy Complicated by Venous Thrombosis. Annals of vascular diseases. 2018.03; 11 (1): 106-111. ( PubMed , DOI )

  9. Inaba O, Nitta J, Miwa N, Yamaguchi J, Nagata Y, Hirao K: Clinical and electrophysiological features of respiratory cycle-dependent atrial tachycardia: An analysis of three cases. HeartRhythm case reports. 2018.01; 4 (1): 18-21. ( PubMed , DOI )

  1. Hara N, Miyamoto T, Iwai T, Yamaguchi J, Hijikata S, Watanabe K, Sagawa Y, Masuda R, Miyazaki R, Miwa N, Sekigawa M, Yamaguchi T, Nagata Y, Nozato T, Obayashi T: Assessment of the Safety and Efficacy of Edoxaban for the Treatment of Venous Thromboembolism Secondary to Active Malignancy. Annals of vascular diseases. 2017.12; 10 (4): 407-410. ( PubMed , DOI )

  2. Yamaguchi J, Hara N, Yamaguchi T, Nagata Y, Nozato T, Miyamoto T: Successful treatment of a massive pulmonary embolism using rivaroxaban in a patient with antithrombin III deficiency. Journal of cardiology cases. 2017.11; 16 (5): 144-147. ( PubMed , DOI )

  3. Hiroko Nagata, Mina Nakagawa, Yasuhiro Asahina, Ayako Sato, Yu Asano, Tomoyuki Tsunoda, Masato Miyoshi, Shun Kaneko, Satoshi Otani, Fukiko Kawai-Kitahata, Miyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Toshihiko Nouchi, Hideki Sakai, Makoto Tomita, Mamoru Watanabe: Effect of interferon-based and -free therapy on early occurrence and recurrence of hepatocellular carcinoma in chronic hepatitis C. J. Hepatol. 2017.11; 67 (5): 933-939. ( PubMed , DOI )

  4. Nakagawa Mina, Asahina Yasuhiro, Nagata Hiroko, Kaneko Shun, Kawai-Kitahata Fukiko, Murakawa Miyako, Nitta Sayuri, Itsui Yasuhiro, Azuma Seishin, Kakinuma Sei, Tanaka Yujiro, Watanabe Mamoru: Evaluation of an early occurrence and recurrence of hepatocellular carcinoma in chronic hepatitis C patients treated with All-Oral DAAs - propensity score-matched analysis of a prospective database HEPATOLOGY. 2017.10; 66 38A-39A.

  5. Murakawa Miyako, Asahina Yasuhiro, Nakagawa Mina, Nitta Sayuri, Kawai-Kitahata Fukiko, Nagata Hiroko, Kaneko Syun, Asano Yu, Miyoshi Masato, Tsunoda Tomoyuki, Inoue-Shinomiya Emi, Sato Ayako, Itsui Yasuhiro, Kakinuma Sei, Azuma Seishin, Watanabe Mamoru: On-treatment higher levels of alpha-fetoprotein and M2BPGi are associated with development of hepatocellular carcinoma during nucleos(t)ide analog therapy in patients with HBV chronic infection HEPATOLOGY. 2017.10; 66 507A.

  6. Nitta Sayuri, Murakawa Miyako, Kato Takanobu, Sato Ayako, Tsunoda Tomoyuki, Miyoshi Masato, Asano Yu, Kaneko Shun, Nagata Hiroko, Kawai-Kitahata Fukiko, Itsui Yasuhiro, Nakagawa Mina, Azuma Seishin, Kakinuma Sei, Asahina Yasuhiro: The analysis of NS5A Resistance-Associated Substitutions (RAS): In vitro study of NS5A recombinant hepatitis C in infectious cell culture system for various RAS detected after treatment failure in chronic hepatitis C patients HEPATOLOGY. 2017.10; 66 480A.

  7. Kaneko Shun, Kakinuma Sei, Asahina Yasuhiro, Kamiya Akihide, Miyoshi Masato, Tsunoda Tomoyuki, Inoue-Shinomiya Emi, Nitta Sayuri, Sato Ayako, Asano Yu, Nagata Hiroko, Kawai-Kitahata Fukiko, Murakawa Miyako, Itsui Yasuhiro, Nakagawa Mina, Azuma Seishin, Watanabe Mamoru: A novel culture model for coinfection of hepatitis B and hepatitis C viruses using human induced pluripotent stem cell-derived hepatic cells for analyses of changes in host-innate immune responses HEPATOLOGY. 2017.10; 66 69A.

  8. Azuma Seishin, Asahina Yasuhiro, Kakinuma Sei, Azuma Keiko, Watanabe Mamoru: Diabetic retinopathy as a risk factor associated with development of hepatocellular carcinoma in non-alcoholic fatty liver disease JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2017.09; 32 158.

  9. Yamaguchi T, Miyamoto T, Iwai T, Yamaguchi J, Hijikata S, Miyazaki R, Miwa N, Sekigawa M, Hara N, Nagata Y, Nozato T, Yamauchi Y, Obayashi T, Isobe M: Prognosis of super-elderly healthy Japanese patients after pacemaker implantation for bradycardia. Journal of cardiology. 2017.07; 70 (1): 18-22. ( PubMed , DOI )

  10. Hijikata S, Miyamoto T, Yamaguchi J, Iwai T, Watanabe K, Sagawa Y, Masuda R, Miyazaki R, Miwa N, Sekigawa M, Yamaguchi T, Hara N, Nagata Y, Nozato T, Sakurai U, Hirao K: Recurrent pulmonary emboli with characteristic histopathology. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. 2017.07; 29 45-47. ( PubMed , DOI )

  11. Yamaguchi J, Miyamoto T, Hara N, Yamaguchi T, Umemoto T: Omental flap transposition for inferior vena cava filter penetration. Radiology case reports. 2017.03; 12 (1): 81-83. ( PubMed , DOI )

  12. Miyako Murakawa, Yasuhiro Asahina, Hiroko Nagata, Mina Nakagawa, Sei Kakinuma, Sayuri Nitta, Fukiko Kawai-Kitahata, Satoshi Otani, Shun Kaneko, Masato Miyoshi, Tomoyuki Tsunoda, Yu Asano, Ayako Sato, Yasuhiro Itsui, Seishin Azuma, Toshihiko Nouchi, Yohei Furumoto, Tooru Asano, Yoshimichi Chuganji, Shuji Tohda, Mamoru Watanabe: ITPA gene variation and ribavirin-induced anemia in patients with genotype 2 chronic hepatitis C treated with sofosbuvir plus ribavirin. Hepatol. Res.. 2017.01; ( PubMed , DOI )

  1. Miyako Murakawa, Yasuhiro Asahina, Fukiko Kawai-Kitahata, Mina Nakagawa, Sayuri Nitta, Satoshi Otani, Hiroko Nagata, Shun Kaneko, Yu Asano, Tomoyuki Tsunoda, Masato Miyoshi, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Yasuhito Tanaka, Sayuki Iijima, Kaoru Tsuchiya, Namiki Izumi, Shuji Tohda, Mamoru Watanabe: Hepatic IFNL4 expression is associated with non-response to interferon-based therapy through the regulation of basal interferon-stimulated gene expression in chronic hepatitis C patients. [Epub ahead of print] J. Med. Virol.. 2016.12; ( PubMed , DOI )

  2. Masato Miyoshi, Sei Kakinuma, Yoko Tanabe, Koji Ishii, Tian-Cheng Li, Takaji Wakita, Yukio Tsuura, Hideki Watanabe, Yasuhiro Asahina, Mamoru Watanabe, Takaaki Ikeda: Chronic Hepatitis E Infection in a Persistently Immunosuppressed Patient Unable to Be Eliminated after Ribavirin Therapy. Intern. Med. 2016.10; 55 (19): 2811-2817. ( PubMed , DOI )

  3. Fumio Goto, Sei Kakinuma, Masato Miyoshi, Tomoyuki Tsunoda, Shun Kaneko, Ayako Sato, Yu Asano, Satoshi Otani, Seishin Azuma, Hiroko Nagata, Fukiko Kawai-Kitahata, Miyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Mina Nakagawa, Yasuhiro Asahina, Mamoru Watanabe: Bone morphogenetic protein-4 modulates proliferation and terminal differentiation of fetal hepatic stem/progenitor cells. Hepatol. Res. 2016.09; 47 (9): 941-952. ( PubMed , DOI )

  4. Shun Kaneko, Sei Kakinuma, Yasuhiro Asahina, Akihide Kamiya, Masato Miyoshi, Tomoyuki Tsunoda, Sayuri Nitta, Yu Asano, Hiroko Nagata, Satoshi Otani, Fukiko Kawai-Kitahata, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Hiromitsu Nakauchi, Hironori Nishitsuji, Saneyuki Ujino, Kunitada Shimotohno, Masashi Iwamoto, Koichi Watashi, Takaji Wakita, Mamoru Watanabe: Human induced pluripotent stem cell-derived hepatic cell lines as a new model for host interaction with hepatitis B virus. Sci Rep. 2016.07; 6 29358. ( PubMed , DOI )

  5. Hiroko Nagata, Mina Nakagawa, Yuki Nishimura-Sakurai, Yu Asano, Tomoyuki Tsunoda, Masato Miyoshi, Shun Kaneko, Fumio Goto, Satoshi Otani, Fukiko Kawai-Kitahata, Miyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Naoko Tojo, Shuji Tohda, Yasuhiro Asahina, Mamoru Watanabe, : Serial measurement of Wisteria floribunda agglutinin positive Mac-2-binding protein is useful for predicting liver fibrosis and the development of hepatocellular carcinoma in chronic hepatitis C patients treated with IFN-based and IFN-free therapy.[Epub ahead of print] Hepatol Int. 2016.07; ( PubMed , DOI )

  6. Seishin Azuma, Yasuhiro Asahina, Yuki Nishimura-Sakurai, Sei Kakinuma, Shun Kaneko, Hiroko Nagata, Fumio Goto, Satoshi Ootani, Fukiko Kawai-Kitahata, Miki Taniguchi, Miyako Murakawa, Takako Watanabe, Megumi Tasaka-Fujita, Yasuhiro Itsui, Mina Nakagawa, Mamoru Watanabe: Efficacy of additional radiofrequency ablation after transcatheter arterial chemoembolization for intermediate hepatocellular carcinoma. Hepatol. Res.. 2016.04; 46 (4): 312-319. ( PubMed , DOI )

  7. Miki Taniguchi, Megumi Tasaka-Fujita, Mina Nakagawa, Takako Watanabe, Fukiko Kawai-Kitahata, Satoshi Otani, Fumio Goto, Hiroko Nagata, Shun Kaneko, Sayuri Nitta, Miyako Murakawa, Yuki Nishimura-Sakurai, Seishin Azuma, Yasuhiro Itsui, Kenichi Mori, Shintaro Yagi, Sei Kakinuma, Yasuhiro Asahina, Mamoru Watanabe: Evaluation of Interferon Resistance in Newly Established Genotype 1b Hepatitis C Virus Cell Culture System. J Clin Transl Hepatol. 2016.03; 4 (1): 5-11. ( PubMed , DOI )

  8. Satoshi Otani, Sei Kakinuma, Akihide Kamiya, Fumio Goto, Shun Kaneko, Masato Miyoshi, Tomoyuki Tsunoda, Yu Asano, Fukiko Kawai-Kitahata, Sayuri Nitta, Toru Nakata, Ryuichi Okamoto, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Yasuhiro Asahina, Tomoyuki Yamaguchi, Naohiko Koshikawa, Motoharu Seiki, Hiromitsu Nakauchi, Mamoru Watanabe: Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells. Biochem. Biophys. Res. Commun.. 2016.01; 469 (4): 1062-1068. ( PubMed , DOI )

  1. Fukiko Kawai-Kitahata, Yasuhiro Asahina, Shinji Tanaka, Sei Kakinuma, Miyako Murakawa, Sayuri Nitta, Takako Watanabe, Satoshi Otani, Miki Taniguchi, Fumio Goto, Hiroko Nagata, Shun Kaneko, Megumi Tasaka-Fujita, Yuki Nishimura-Sakurai, Seishin Azuma, Yasuhiro Itsui, Mina Nakagawa, Minoru Tanabe, Shinichi Takano, Mitsuharu Fukasawa, Minoru Sakamoto, Shinya Maekawa, Nobuyuki Enomoto, Mamoru Watanabe: Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J. Gastroenterol. 2015.11; ( PubMed , DOI )

  2. Yamaguchi J, Miyamoto T, Arai Y, Hirao T, Umemoto T, Yamauchi Y, Suzaki S, Obayashi T: Shock After Successful Primary Percutaneous Coronary Intervention for Ventricular Fibrillation. Circulation. 2015.09; 132 (10): e135-6. ( PubMed , DOI )

  3. Miyako Murakawa, Yasuhiro Asahina, Mina Nakagawa, Naoya Sakamoto, Sayuri Nitta, Akiko Kusano-Kitazume, Takako Watanabe, Fukiko Kawai-Kitahata, Satoshi Otani, Miki Taniguchi, Fumio Goto, Yuki Nishimura-Sakurai, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Mamoru Watanabe: Impaired induction of interleukin 28B and expression of interferon λ 4 associated with nonresponse to interferon-based therapy in chronic hepatitis C. J. Gastroenterol. Hepatol. 2015.06; 30 (6): 1075-1084. ( PubMed , DOI )

  1. Yoshihito Kano, Sei Kakinuma, Fumio Goto, Seishin Azuma, Yuki Nishimura-Sakurai, Yasuhiro Itsui, Mina Nakagawa, Atsushi Kudo, Minoru Tanabe, Susumu Kirimura, Tomonori Amano, Takashi Ito, Takumi Akashi, Yasuhiro Asahina, Mamoru Watanabe: Primary hepatic neuroendocrine carcinoma with a cholangiocellular carcinoma component in one nodule. Clin J Gastroenterol. 2014.10; 7 (5): 449-454. ( PubMed , DOI )

  2. Yasuhiro Asahina, Kaoru Tsuchiya, Takashi Nishimura, Masaru Muraoka, Yuichiro Suzuki, Nobuharu Tamaki, Yutaka Yasui, Takanori Hosokawa, Ken Ueda, Hiroyuki Nakanishi, Jun Itakura, Yuka Takahashi, Masayuki Kurosaki, Nobuyuki Enomoto, Mina Nakagawa, Sei Kakinuma, Mamoru Watanabe, Namiki Izumi: Genetic variation near interleukin 28B and the risk of hepatocellular carcinoma in patients with chronic hepatitis C. J. Gastroenterol. 2014.07; 49 (7): 1152-1162. ( PubMed , DOI )

  1. Yasuhiro Asahina, Kaoru Tsuchiya, Takashi Nishimura, Masaru Muraoka, Yuichiro Suzuki, Nobuharu Tamaki, Yutaka Yasui, Takanori Hosokawa, Ken Ueda, Hiroyuki Nakanishi, Jun Itakura, Yuka Takahashi, Masayuki Kurosaki, Nobuyuki Enomoto, Mina Nakagawa, Sei Kakinuma, Mamoru Watanabe, Namiki Izumi: α-fetoprotein levels after interferon therapy and risk of hepatocarcinogenesis in chronic hepatitis C. Hepatology. 2013.10; 58 (4): 1253-1262. ( PubMed , DOI )

  2. Kei Kiyohashi, Sei Kakinuma, Akihide Kamiya, Naoya Sakamoto, Sayuri Nitta, Hideto Yamanaka, Kouhei Yoshino, Junko Fujiki, Miyako Murakawa, Akiko Kusano-Kitazume, Hiromichi Shimizu, Ryuichi Okamoto, Seishin Azuma, Mina Nakagawa, Yasuhiro Asahina, Naoki Tanimizu, Akira Kikuchi, Hiromitsu Nakauchi, Mamoru Watanabe: Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013.06; 57 (6): 2502-2513. ( PubMed , DOI )

  3. Sayuri Nitta, Naoya Sakamoto, Mina Nakagawa, Sei Kakinuma, Kako Mishima, Akiko Kusano-Kitazume, Kei Kiyohashi, Miyako Murakawa, Yuki Nishimura-Sakurai, Seishin Azuma, Megumi Tasaka-Fujita, Yasuhiro Asahina, Mitsutoshi Yoneyama, Takashi Fujita, Mamoru Watanabe: Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type I interferon-dependent innate immunity. Hepatology. 2013.01; 57 (1): 46-58. ( PubMed , DOI )

  1. Kusano-Kitazume Akiko, Sakamoto Naoya, Okuno Yukiko, Sekine-Osajima Yuko, Nakagawa Mina, Kakinuma Sei, Kiyohashi Kei, Nitta Sayuri, Murakawa Miyako, Azuma Seishin, Nishimura-Sakurai Yuki, Hagiwara Masatoshi, Watanabe Mamoru: Identification of novel N-(morpholine-4-carbonyloxy) amidine compounds as potent inhibitors against hepatitis C virus replication. Antimicrob Agents Chemother. 2012.03; 56 (3): 1315-1323. ( PubMed , DOI )

  2. Masayuki Kurosaki, Naoki Hiramatsu, Minoru Sakamoto, Yoshiyuki Suzuki, Manabu Iwasaki, Akihiro Tamori, Kentaro Matsuura, Sei Kakinuma, Fuminaka Sugauchi, Naoya Sakamoto, Mina Nakagawa, Namiki Izumi: Data mining model using simple and readily available factors could identify patients at high risk for hepatocellular carcinoma in chronic hepatitis C. J. Hepatol.. 2012.03; 56 (3): 602-608. ( PubMed , DOI )

  3. Masayuki Kurosaki, Naoki Hiramatsu, Minoru Sakamoto, Yoshiyuki Suzuki, Manabu Iwasaki, Akihiro Tamori, Kentaro Matsuura, Sei Kakinuma, Fuminaka Sugauchi, Naoya Sakamoto, Mina Nakagawa, Hiroshi Yatsuhashi, Namiki Izumi: Age and total ribavirin dose are independent predictors of relapse after interferon therapy in chronic hepatitis C revealed by data mining analysis. Antivir. Ther. (Lond.). 2012.01; 17 (1): 35-43. ( PubMed , DOI )

  1. Naoki Hiramatsu, Masayuki Kurosaki, Naoya Sakamoto, Manabu Iwasaki, Minoru Sakamoto, Yoshiyuki Suzuki, Fuminaka Sugauchi, Akihiro Tamori, Sei Kakinnuma, Kentaro Matsuura, Namiki Izumi: Pretreatment prediction of anemia progression by pegylated interferon alpha-2b plus ribavirin combination therapy in chronic hepatitis C infection: decision-tree analysis. J. Gastroenterol.. 2011.09; 46 (9): 1111-1119. ( PubMed , DOI )

  2. Funaoka Y, Sakamoto N, Suda G, Itsui Y, Nakagawa M, Kakinuma S, Watanabe T, Mishima K, Ueyama M, Onozuka I, Nitta S, Kitazume A, Kiyohashi K, Murakawa M, Azuma S, Tsuchiya K, Watanabe M: Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 91. J Virol. 2011.06; 85 (12): 5986-5994. ( PubMed , DOI )

  3. Watanabe T, Sakamoto N, Nakagawa M, Kakinuma S, Itsui Y, Nishimura-Sakurai Y, Ueyama M, Funaoka Y, Kitazume A, Nitta S, Kiyohashi K, Murakawa M, Azuma S, Tsuchiya K, Oooka S, Watanabe M: Inhibitory Effect of a Triterpenoid Compound, with or without Alpha Interferon, on Hepatitis C Virus Infection. Antimicrob Agents Chemother. 2011.06; 55 (6): 2537-2545. ( PubMed , DOI )

  4. Sakamoto N, Nakagawa M, Tanaka Y, Sekine-Osajima Y, Ueyama M, Kurosaki M, Nishida N, Tamori A, Yuki NS, Itsui Y, Azuma S, Kakinuma S, Hige S, Itoh Y, Tanaka E, Hiasa Y, Izumi N, Tokunaga K, Mizokami M, Watanabe M: Association of IL28B variants with response to pegylated-interferon alpha plus ribavirin combination therapy reveals intersubgenotypic differences between genotypes 2a and 2b. J Med Virol. 2011.05; 83 (5): 871-878. ( PubMed , DOI )

  5. Yamamoto M, Sakamoto N, Nakamura T, Itsui Y, Nakagawa M, Nishimura-Sakurai Y, Kakinuma S, Azuma S, Tsuchiya K, Kato T, Wakita T, Watanabe M: Studies on virus kinetics using infectious fluorescence-tagged hepatitis C virus cell culture. Hepatol Res. 2011.03; 41 (3): 258-269. ( PubMed , DOI )

  6. Izumi Onozuka, Sei Kakinuma, Akihide Kamiya, Masato Miyoshi, Naoya Sakamoto, Kei Kiyohashi, Takako Watanabe, Yusuke Funaoka, Mayumi Ueyama, Mina Nakagawa, Naohiko Koshikawa, Motoharu Seiki, Hiromitsu Nakauchi, Mamoru Watanabe: Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice. Biochem. Biophys. Res. Commun.. 2011.03; 406 (1): 134-140. ( PubMed , DOI )

  7. Ueyama M, Nakagawa M, Sakamoto N, Onozuka I, Funaoka Y, Watanabe T, Nitta S, Kiyohashi K, Kitazume A, Murakawa M, Nishimura-Sakurai Y, Sekine-Osajima Y, Itsui Y, Azuma S, Kakinuma S, Watanabe M:: Serum interleukin-6 levels correlate with resistance to treatment of chronic hepatitis C infection with pegylated-interferon-α2b plus ribavirin. Antiviral Therapy. 2011; 16 1081-1091. ( PubMed , DOI )

  1. Suda G, Sakamoto N, Itsui Y, Nakagawa M, Tasaka-Fujita M, Funaoka Y, Watanabe T, Nitta S, Kiyohashi K, Azuma S, Kakinuma S, Tsuchiya K, Imamura M, Hiraga N, Chayama K, Watanabe M: IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones. Virology. 2010.11; 407 (1): 80-90. ( PubMed , DOI )

  2. Sakamoto N, Tanaka Y, Nakagawa M, Yatsuhashi H, Nishiguchi S, Enomoto N, Azuma S, Nishimura-Sakurai Y, Kakinuma S, Nishida N, Tokunaga K, Honda M, Ito K, Mizokami M, Watanabe M: ITPA gene variant protects against anemia induced by pegylated interferon-alpha and ribavirin therapy for Japanese patients with chronic hepatitis C. Hepatol Res. 2010.11; 40 (11): 1063-1071. ( PubMed , DOI )

  3. Mishima K, Sakamoto N, Sekine-Osajima Y, Nakagawa M, Itsui Y, Azuma S, Kakinuma S, Kiyohashi K, Kitazume A, Tsuchiya K, Imamura M, Hiraga N, Chayama K, Wakita T, Watanabe M: Cell culture and in vivo analyses of cytopathic hepatitis C virus mutants. Virology. 2010.09; 405 (2): 361-369. ( PubMed , DOI )

  4. Karakama Y, Sakamoto N, Itsui Y, Nakagawa M, Tasaka-Fujita M, Nishimura-Sakurai Y, Kakinuma S, Oooka M, Azuma S, Tsuchiya K, Onogi H, Hagiwara M, Watanabe M: Inhibition of hepatitis C virus replication by a specific inhibitor of serine-arginine-rich protein kinase. Antimicrob Agents Chemother. 2010.08; 54 (8): 3179-3186. ( PubMed , DOI )

  5. Nakagawa M, Sakamoto N, Ueyama M, Mogushi K, Nagaie S, Itsui Y, Azuma S, Kakinuma S, Tanaka H, Enomoto N, Watanabe M: Mutations in the interferon sensitivity determining region and virological response to combination therapy with pegylated-interferon alpha 2b plus ribavirin in patients with chronic hepatitis C-1b infection. J Gastroenterol. 2010.06; 45 (6): 656-665. ( PubMed , DOI )

  6. Nishimura-Sakurai Y, Sakamoto N, Mogushi K, Nagaie S, Nakagawa M, Itsui Y, Tasaka-Fujita M, Onuki-Karakama Y, Suda G, Mishima K, Yamamoto M, Ueyama M, Funaoka Y, Watanabe T, Azuma S, Sekine-Osajima Y, Kakinuma S, Tsuchiya K, Enomoto N, Tanaka H, Watanabe M: Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells. J Gastroenterol. 2010.05; 45 (5): 523-536. ( PubMed , DOI )

  7. Hitoshi Takizawa, Satoshi Nishimura, Naoya Takayama, Atsushi Oda, Hidekazu Nishikii, Yohei Morita, Sei Kakinuma, Satoshi Yamazaki, Satoshi Okamura, Noriko Tamura, Shinya Goto, Akira Sawaguchi, Ichiro Manabe, Kiyoshi Takatsu, Hiromitsu Nakauchi, Satoshi Takaki, Koji Eto: Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo. J. Clin. Invest.. 2010.01; 120 (1): 179-190. ( PubMed , DOI )

  1. Yasuhiro Itsui, Naoya Sakamoto, Sei Kakinuma, Mina Nakagawa, Yuko Sekine-Osajima, Megumi Tasaka-Fujita, Yuki Nishimura-Sakurai, Gouki Suda, Yuko Karakama, Kako Mishima, Machi Yamamoto, Takako Watanabe, Mayumi Ueyama, Yusuke Funaoka, Seishin Azuma, Mamoru Watanabe: Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein. Hepatology. 2009.12; 50 (6): 1727-1737. ( PubMed , DOI )

  2. Akihide Kamiya, Sei Kakinuma, Yuji Yamazaki, Hiromitsu Nakauchi: Enrichment and clonal culture of progenitor cells during mouse postnatal liver development in mice. Gastroenterology. 2009.09; 137 (3): 1114-26, 1126.e1. ( PubMed , DOI )

  3. Sei Kakinuma, Haruhiko Ohta, Akihide Kamiya, Yuji Yamazaki, Tsunekazu Oikawa, Ken Okada, Hiromitsu Nakauchi: Analyses of cell surface molecules on hepatic stem/progenitor cells in mouse fetal liver. J. Hepatol.. 2009.07; 51 (1): 127-138. ( PubMed , DOI )

  4. Sei Kakinuma, Hiromitsu Nakauchi, Mamoru Watanabe: Hepatic stem/progenitor cells and stem-cell transplantation for the treatment of liver disease. J. Gastroenterol.. 2009.03; 44 (3): 167-172. ( PubMed , DOI )

  5. Tsunekazu Oikawa, Akihide Kamiya, Sei Kakinuma, Mikio Zeniya, Ryuichi Nishinakamura, Hisao Tajiri, Hiromitsu Nakauchi: Sall4 regulates cell fate decision in fetal hepatic stem/progenitor cells. Gastroenterology. 2009.03; 136 (3): 1000-1011. ( PubMed , DOI )

  1. Akihide Kamiya, Sei Kakinuma, Masafumi Onodera, Atsushi Miyajima, Hiromitsu Nakauchi: Prospero-related homeobox 1 and liver receptor homolog 1 coordinately regulate long-term proliferation of murine fetal hepatoblasts. Hepatology. 2008.07; 48 (1): 252-264. ( PubMed , DOI )

  1. Kakinuma S, Asahina K, Okamura K, Teramoto K, Tateno C, Yoshizato K, Tanaka Y, Yasumizu T, Sakamoto N, Watanabe M, Teraoka H: Human cord blood cells transplanted into chronically damaged liver exhibit similar characteristics to functional hepatocytes. Transplant Proc. 2007.01; 39 (1): 240-243. ( PubMed , DOI )

  1. Itsui Y, Sakamoto N, Kurosaki M, Kanazawa N, Tanabe Y, Koyama T, Takeda Y, Nakagawa M, Kakinuma S, Sekine Y, Maekawa S, Enomoto N, Watanabe M: Expressional screening of interferon-stimulated genes for antiviral activity against hepatitis C virus replication. J Viral Hepat. 2006.10; 13 (10): 690-700. ( PubMed , DOI )

  2. Kohashi T, Maekawa S, Sakamoto N, Kurosaki M, Watanabe H, Tanabe Y, Chen CH, Kanazawa N, Nakagawa M, Kakinuma S, Yamashiro T, Itsui Y, Koyama T, Enomoto N, Watanabe M: Site-specific mutation of the interferon sensitivity-determining region (ISDR) modulates hepatitis C virus replication. J Viral Hepat. 2006.09; 13 (9): 582-590. ( PubMed , DOI )

  3. Koyama T, Sakamoto N, Tanabe Y, Nakagawa M, Itsui Y, Takeda Y, Kakinuma S, Sekine Y, Maekawa S, Yanai Y, Kurimoto M, Watanabe M: Divergent activities of interferon-alpha subtypes against intracellular hepatitis C virus replication. Hepatol Res. 2006.01; 34 (1): 41-49. ( PubMed , DOI )

  1. Hamano K, Sakamoto N, Enomoto N, Izumi N, Asahina Y, Kurosaki M, Ueda E, Tanabe Y, Maekawa S, Itakura J, Watanabe H, Kakinuma S, Watanabe M: Mutations in the NS5B region of the hepatitis C virus genome correlate with clinical outcomes of interferon-alpha plus ribavirin combination therapy. J Gastroenterol Hepatol. 2005.09; 20 (9): 1401-1409. ( PubMed , DOI )

  2. Mina Nakagawa, Naoya Sakamoto, Yoko Tanabe, Tomoyuki Koyama, Yasuhiro Itsui, Yoshie Takeda, Cheng-Hsin Chen, Sei Kakinuma, Shinya Oooka, Shinya Maekawa, Nobuyuki Enomoto, Mamoru Watanabe: Suppression of hepatitis C virus replication by cyclosporin a is mediated by blockade of cyclophilins. Gastroenterology. 2005.09; 129 (3): 1031-1041. ( PubMed , DOI )

  3. Chen CH, Nagayama K, Enomoto N, Miyasaka Y, Kurosaki M, Sakamoto N, Maekawa S, Kakinuma S, Ikeda T, Izumi N, Sato C, Watanabe M: Enhancement of mitochondrial gene expression in the liver of primary biliary cirrhosis. Hepatol Res. 2005.01; 31 (1): 24-30. ( PubMed , DOI )

  1. Kanazawa N, Kurosaki M, Sakamoto N, Enomoto N, Itsui Y, Yamashiro T, Tanabe Y, Maekawa S, Nakagawa M, Chen CH, Kakinuma S, Oshima S, Nakamura T, Kato T, Wakita T, Watanabe M: Regulation of hepatitis C virus replication by interferon regulatory factor 1. J Virol. 2004.09; 78 (18): 9713-9720. ( PubMed , DOI )

  2. Tanabe Y, Sakamoto N, Enomoto N, Kurosaki M, Ueda E, Maekawa S, Yamashiro T, Nakagawa M, Chen CH, Kanazawa N, Kakinuma S, Watanabe M: Synergistic inhibition of intracellular hepatitis C virus replication by combination of ribavirin and interferon- alpha. J Infect Dis. 2004.04; 189 (7): 1129-1139. ( PubMed , DOI )

  3. Nakagawa M, Sakamoto N, Enomoto N, Tanabe Y, Kanazawa N, Koyama T, Kurosaki M, Maekawa S, Yamashiro T, Chen CH, Itsui Y, Kakinuma S, Watanabe M: Specific inhibition of hepatitis C virus replication by cyclosporin A. Biochem Biophys Res Commun. 2004.01; 313 (1): 42-47. ( PubMed )

  1. Sei Kakinuma, Yujiro Tanaka, Ryoko Chinzei, Mamoru Watanabe, Keiko Shimizu-Saito, Yuzuru Hara, Kenichi Teramoto, Shigeki Arii, Chifumi Sato, Kozo Takase, Takehiko Yasumizu, Hirobumi Teraoka: Human umbilical cord blood as a source of transplantable hepatic progenitor cells. Stem Cells. 2003.03; 21 (2): 217-227. ( PubMed , DOI )

  1. Ono K, Tanaka Y, Kusano F, Kakinuma S, Ishidate K, Watanabe M, Marumo F, Sato C: Fas-ligand and perforin expression in infiltrating cytotoxic T lymphocytes in the liver of chronic hepatitis C. Hepatol Res. 2002.07; 23 (3): 153-162. ( PubMed )

  2. Chinzei R, Tanaka Y, Shimizu-Saito K, Hara Y, Kakinuma S, Watanabe M, Teramoto K, Arii S, Takase K, Sato C, Terada N, Teraoka H: Embryoid-body cells derived from a mouse embryonic stem cell line show differentiation into functional hepatocytes. Hepatology. 2002.07; 36 (1): 22-29. ( PubMed , DOI )

  1. Ohbayashi H, Tanaka Y, Ohoka S, Chinzei R, Kakinuma S, Goto M, Watanabe M, Marumo F, Sato C: TT virus is shown in the liver by in situ hybridization with a PCR-generated probe from the serum TTV-DNA. J Gastroenterol Hepatol. 2001.04; 16 (4): 424-428. ( PubMed )

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