生命理工学系専攻

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  1. Yoshihide Hashimoto,Jun Negishi, Seiichi Funamoto, Tsuyoshi Kimura,Hisatoshi Kobayashi, Tetsuro Oshika , Akio Kishida: Preparation, physico-biochemical characterization, and proteomic analysis of highly transparent corneal extracellular matrices for lamellar keratoplasty and tissue-engineered cornea construction Materials Today Bio. 2024.09; 28 ( DOI )

  2. Kobayakawa T, Tsuji K, Tamamura H: Design, synthesis and evaluation of bioactivity of peptidomimetics based on chloroalkene dipeptide isosteres. Bioorganic & medicinal chemistry. 2024.08; 110 117811. ( PubMed , DOI )

  3. Imai D, Numoto N, Tokiwa H, Kakuta H, Ito N: Structural basis for the full and partial agonist activities of retinoid X receptor α ligands with an iso-butoxy and an isopropyl group. Biochemical and biophysical research communications. 2024.08; 734 150617. ( PubMed , DOI )

  4. Taguchi Y, Toma K, Iitani K, Arakawa T, Iwasaki Y, Mitsubayashi K: Long-range surface plasmon hydrogel aptasensor for sensitive, selective, and continuous measurement of vancomycin Sensors and Actuators: B. Chemical. 2024.08; 413 135882.

  5. Kenta Iitani, Mika Suzuki, Kenta Ichikawa, Koji Toma, Takahiro Arakawa, Kohji Mitsubayashi: Image Sensing of Gaseous Acetone Using Secondary Alcohol Dehydrogenase-Immobilized Mesh for Exhaled Air Analytical Chemistry. 2024.07; 96 (28): 11549-11556.

  6. Jun Negishi, Dan Tanaka, Yoshihide Hashimoto: Induction of osteogenic differentiation by the extracellular matrix of fetal bone tissues and adult cartilage Tissue Cell. 2024.07; 90 102475.

  7. Ayana Yamaguchi, Yoshihide Hashimoto, Jun Negishi: Fabrication of a cell culture scaffold that mimic the composition and structure of bone marrow extracellular matrix J Biosci Bioeng. 2024.07; 138 (1): 83-88.

  8. Kenta Ichikawa, Kenta Iitani, Gentaro Kawase, Koji Toma, Takahiro Arakawa, Dzung Viet Dao, Kohji Mitsubayashi: Real-time salivary turbidity measurement with a mouthguard-type wearable sensor Sensors and Actuators A: Physical. 2024.06; 376 115660.

  9. Yoshida M, Hanazono Y, Numoto N, Nagao S, Yabuno S, Kitagawa Y, Sekiguchi H, Ito N, Azuma T, Oda M: Affinity-matured antibody with a disulfide bond in H-CDR3 loop. Archives of biochemistry and biophysics. 2024.06; 758 110068. ( PubMed , DOI )

  10. Kenta Iitani, Kenta Ichikawa, Koji Toma, Takahiro Arakawa, Kohji Mitsubayashi: Biofluorometric Gas-Imaging System for Evaluating the Ripening Stages of “La France” Pear Based on Ethanol Vapor Emitted via the Epicarp ACS Sensors. 2024.06;

  11. Akatsu C, Tsuneshige T, Numoto N, Long W, Uchiumi T, Kaneko Y, Asano M, Ito N, Tsubata T: CD72 is an inhibitory pattern recognition receptor that recognizes ribosomes and suppresses production of anti-ribosome autoantibody. Journal of autoimmunity. 2024.05; 146 103245. ( PubMed , DOI )

  12. Omori S, Hanazono Y, Nishi H, Kinoshita K: The role of the STAS domain in SLC26A9 for chloride ion transporter function. Biophysical journal. 2024.05; 123 (12): 1751-1762. ( PubMed , DOI )

  13. Taguchi Y, Toma K, Iitani K, Arakawa T, Iwasaki Y, Mitsubayashi K: In Vitro Performance of a Long-Range Surface Plasmon Hydrogel Aptasensor for Continuous and Real-Time Vancomycin Measurement in Human Serum ACS Applied Materials & Interfaces. 2024.05; 16 (22): 28162-28171.

  14. Ishii T, Kobayakawa T, Matsuda K, Nigorikawa K, Bolah P, Noborio A, Tsuji K, Ohashi N, Yoshimura K, Nomura W, Mitsuya H, Maeda K, Tamamura H: Discovery of Potent DAG-Lactone Derivatives as HIV Latency Reversing Agents. ACS infectious diseases. 2024.05; 10 (6): 2250-2261. ( PubMed , DOI )

  15. Narai-Kanayama A, Hayakawa S, Yoshino T, Honda F, Matsuda H, Oishi Y: Differential effects of theasinensins and epigallocatechin-3-O-gallate on phospholipid bilayer structure and liposomal aggregation. Biochimica et biophysica acta. Biomembranes. 2024.04; 1866 (5): 184312. ( PubMed , DOI )

  16. Oishi, Y; Koike, H; Kumagami, N; Nakagawa, Y; Araki, M; Taketomi, Y; Miki, Y; Matsuda, S; Kim, H; Matsuzaka, T; Ozawa, H; Shimano, H; Murakami, M; Manabe, I: Macrophage SREBP1 regulates skeletal muscle regeneration (vol 14, 1251784, 2024) FRONTIERS IN IMMUNOLOGY. 2024.04; 15 1382077. ( PubMed , DOI )

  17. Sreypich Say,Mika Suzuki,Yoshihide Hashimoto,Tsuyoshi Kimura,Akio Kishida : Investigation of anti-adhesion ability of 8-arm PEGNHS-modified porcine pericardium Biomed Mater. 2024.03; 12 (19(3)): ( DOI )

  18. Shiino H, Tashiro S, Hashimoto M, Sakata Y, Hosoya T, Endo T, Kojima H, Tamura Y: Chemical inhibition of phosphatidylcholine biogenesis reveals its role in mitochondrial division. iScience. 2024.03; 27 (3): 109189. ( PubMed , DOI )

  19. Sukhorukov VN, Khotina VA, Borodko DD, Ekta MB, Oishi Y, Omelchenko AV, Kolmychkova KI, Nikiforov NG, Sobenin IA, Orekhov AN: Evidence for the Involvement of Gene Regulation of Inflammatory Molecules in the Accumulation of Intracellular Cholesterol: The Mechanism of Foam Cell Formation in Atherosclerosis. Current medicinal chemistry. 2024.02; ( PubMed , DOI )

  20. Kenta Ichikawa, Kenta Iitani, Gentaro Kawase, Koji Toma, Takahiro Arakawa, Dzung Viet Dao, and Kohji Mitsubayashi: Mouthguard-Type Wearable Sensor for Monitoring Salivary Trudbidity to Assess Oral Hygiene Sensors. 2024.02; 24 1436. ( DOI )

  21. Tsuyoshi Kimura, Hanako Maeda, Moeko Hagiwara, Yoshihide Hashimoto, Naoko Nakamura, Wataru Nomura, Tadao Tanabe, Mako Kobayashi, Masaya Yamamoto, Takahide Matsushima, Hiroshi Asahara, Akio Kishida: Evaluation of Proinflammatory Response to Polymeric Materials Using a Macrophage Cell Line Genetically Tagged with a Luminescent Peptide Advanced Biomedical Engineering. 2024.02; 13 43-51.

  22. Shota Toda, Yoshihide Hashimoto, Naoko Nakamura, Masahiro Yamada, Ryusuke Nakaoka, Wataru Nomura, Masaya Yamamoto, Tsuyoshi Kimura, Akio Kishida: Characteristics of macrophage aggregates prepared by rotation culture and their response to polymeric materials Journal of Artificial Organs. 2024.01;

  23. Kohei Yabuuchi, Toru Katsumata, Tsuyoshi Shimoboji, Yoshihide Hashimoto, Tsuyoshi Kimura, Kazunari Akiyoshi, Akio Kishida: Variable swelling behavior of and drug encapsulation in a maleimide-modified hyaluronic acid nanogel-based hydrogel Polymer Journal. 2024.01;

  24. Oishi, Y; Koike, H; Kumagami, N; Nakagawa, Y; Araki, M; Taketomi, Y; Miki, Y; Matsuda, S; Matsuzaka, T; Ozawa, H; Shimano, H; Murakami, M; Manabe, I: Macrophage SREBP1 regulates skeletal muscle regeneration FRONTIERS IN IMMUNOLOGY. 2024.01; 14 1251784. ( PubMed , DOI )

  25. Shota TODA,Yoshihide HASHIMOTO,Naoko NAKAMURA,Masahiro YAMADA,Ryusuke NAKAOKA,Wataru NOMURA,Masaya YAMAMOTO,Tsuyoshi KIMURA,Akio KISHIDA: Effects of Polymeric Materials on Activation of THP-1 Cell-derived Macrophages during Differentiation Induced by PMA Advanced Biomedical Engineering. 2024.01; 13 1-10. ( DOI )

  26. Watanabe K, Mao Q, Zhang Z, Hata M, Kodera M, Kitagishi H, Niwa T, Hosoya T: Clickable bisreactive small gold nanoclusters for preparing multifunctionalized nanomaterials: application to photouncaging of an anticancer molecule. Chem Sci. 2024.01; 15 (4): 1402-1408. ( PubMed , DOI )

  27. Kobayakawa T, Yokoyama M, Tsuji K, Boku S, Kurakami M, Fujino M, Ishii T, Miura Y, Nishimura S, Shinohara K, Yamamoto K, Bolah P, Kotani O, Murakami T, Sato H, Tamamura H: Development of Small-Molecule Anti-HIV-1 Agents Targeting HIV-1 Capsid Proteins. Chemical & pharmaceutical bulletin. 2024; 72 (1): 41-47. ( PubMed , DOI )

  28. Kobayakawa T, Takano H, Ishii T, Bolah P, Tsuji K, Ohashi N, Nomura W, Furuta T, Tamamura H: Effect of Two-Photon Excitation to 8-Azacoumarin Derivatives as Photolabile Protecting Groups. Chemical & pharmaceutical bulletin. 2024; 72 (3): 311-312. ( PubMed , DOI )

  1. Kohei Tsuji, Takuya Kobayakawa, Takahiro Ishii, Nobuyo Higashi-Kuwata, Chika Azuma, Kouki Shinohara, Yutaro Miura, Kenichi Yamamoto, Soshi Nishimura, Shin-ichiro Hattori, Haydar Bulut, Hiroaki Mitsuya, Hirokazu Tamamura: Exploratory Studies of Effective Inhibitors against the SARS-CoV-2 Main Protease by Halogen Incorporation and Amide Bond Replacement. Chemical and Pharmaceutical Bulletin. 2023.12; 71 (12): 879-886. ( PubMed , DOI )

  2. Say sreypich, Mika Suzuki, Yoshihide Hashimoto, Tsuyoshi Kimura, Akio Kishida: Effect of multi arm-PEG-NHS (polyethylene glycol n-hydroxysuccinimide) branching on cell adhesion to modified decellularized bovine and porcine pericardium Journal of Materials chemistry B. 2023.12; (5): 1244-1256. ( DOI )

  3. Yoshihide Hashimoto, Akitatsu Yamashita, Masaki Tabuchi, Yongwei Zhang, Seiichi Funamoto, Akio Kishida: Fibrin hydrogel layer-anchored pericardial matrix prevents epicardial adhesion in the severe heart adhesion-induced miniature pig model Annals of Biomedical Engineering. 2023.12; 52 282-291. ( PubMed , DOI )

  4. Naoto Washihira, Mika Murakami, Miho Nakamura, Sho Fujii, Takahide Matsushima, Hiroshi Asahara, Akio Kishida, Tadao Tanabe, Tsuyoshi Kimura, Mako Kobayashi, Masaya Yamamoto: Application of a genetically engineered macrophage cell line for evaluating cellular effects of UV/US-treated poly(ethylene terephthalate) microplastics. Colloids and Surface B: Biointerfaces. 2023.12; 234 113735. ( PubMed , DOI )

  5. Geng Zhang, Yuki Maeno, Kenta Iitani, Takahiro Arakawa, Yasuhiko Iwasaki, Koji Toma, and Kohji Mitsubayashi: Enhanced sensitivity of a fluorometric biosensor for alcohol metabolites with an enzymatic cycling reaction Sensors and Actuators: B. Chemical. 2023.11; 401 135031. ( DOI )

  6. Suphatra Hiranphinyophat, Tomoki Hiraoka, Mako Kobayashi, Sho Fujii, Akio Kishida, Tadao Tanabe, Tsuyoshi Kimura, Masaya Yamamoto: Fabrication of polypropylene nanoplastics via thermal oxidation reaction for human cells responsiveness studies Langmuir. 2023.11; 39 (44): 15563-15571. ( PubMed , DOI )

  7. Niwa T, Takimoto T, Sakata Y, Hosoya T: Palladium-Catalyzed #Iipso#IR-Borylation of Aryl Halides Promoted by Lewis Acid-Mediated Electrophilic Activation of Aryl(halo)palladium(II) Complex. Org Lett. 2023.11; 25 (45): 8173-8177. ( PubMed , DOI )

  8. Kohei Yabuuchi, Mika Suzuki, Chen Liang, Yoshihide Hashimoto, Tsuyoshi Kimura, Kazunari Akiyoshi, Akio Kishida.: Preparation of cholesterol-modified hyaluronic acid nanogel-based hydrogel and the inflammatory evaluation using macrophage-like cells Gels. 2023.10; 9 (11): 866. ( DOI )

  9. Mizuki Sato, Tatsuya Kamiyama, Kenta Iitani, Kazuyoshi Yano, Kohji Mitsubayashi, and Takahiro Arakawa: Wearable Biosensor Utilizing Chitosan Biopolymer for Uric Acid Monitoring Journal of Robotics and Mechatronics. 2023.10; 35 (5): 1131-1134. ( DOI )

  10. Pu J, Kofuji S, Okamoto-Uchida Y, Danzaki K, Yu R, Suzuki A, Kitajima S, Nishina H: Lethal Phenotype-Based Database Screening Identifies Ceramide as a Negative Regulator of Primitive Streak Formation. Stem cells (Dayton, Ohio). 2023.10; 41 (12): 1142-1156. ( PubMed , DOI )

  11. Tsuji K, Ishii T, Kobayakawa T, Higashi-Kuwata N, Shinohara K, Azuma C, Miura Y, Nakano H, Wada N, Hattori SI, Bulut H, Mitsuya H, Tamamura H: Structure-Activity Relationship Studies of SARS-CoV-2 Main Protease Inhibitors Containing 4-Fluorobenzothiazole-2-carbonyl Moieties. Journal of medicinal chemistry. 2023.09; 66 (19): 13516-13529. ( PubMed , DOI )

  12. Nishita M, Kamizaki K, Hoshi K, Aruga K, Nishikaku I, Shibuya H, Matsumoto K, Minami Y: Rho family small GTPase Rif regulates Wnt5a-Ror1-Dvl2 signaling and promotes lung adenocarcinoma progression. The Journal of biological chemistry. 2023.09; 299 (10): 105248. ( PubMed , DOI )

  13. Bekker GJ, Numoto N, Kawasaki M, Hayashi T, Yabuno S, Kozono Y, Shimizu T, Kozono H, Ito N, Oda M, Kamiya N: Elucidation of binding mechanism, affinity and complex structure between mWT1 tumor-associated antigen peptide and HLA-A*24:02. Protein Science. 2023.09; 32 (10): e4775. ( PubMed , DOI )

  14. Taguchi J, Okuyama T, Tomita S, Niwa T, Hosoya T: Synthesis of Multisubstituted Aromatics via 3-Triazenylarynes. Org Lett. 2023.09; 25 (38): 7030-7034. ( PubMed , DOI )

  15. Yuya Hanazono, Yu Hirano, Taro Tamada, Kunio Miki: Description of peptide bond planarity from high-resolution neutron crystallography Biophysics and Physicobiology. 2023.09; 20 (3): e200035.

  16. Takahiro Ishii, Takuya Kobayakawa, Kouki Matsuda, Kohei Tsuji, Nami Ohashi, Shingo Nakahata, Airi Noborio, Kazuhisa Yoshimura, Hiroaki Mitsuya, Kenji Maeda, Hirokazu Tamamura: Synthesis and evaluation of DAG-lactone derivatives with HIV-1 latency reversing activity. European Journal of Medicinal Chemistry. 2023.08; 256 115449. ( PubMed , DOI )

  17. Dongzhe Wang, Narintadeach Charoensombut, Kinyoshi Kawabata, Tsuyoshi Kimura, Akio Kishida, Takashi Ushida, Katsuko S. Furukawa: Effect of pressure conditions in uterine decellularization using hydrostatic pressure on structural protein preservation Bioengineering. 2023.07; 10 (7): 814. ( DOI )

  18. Hajime Tajima Sakurai, Hidefumi Iwashita, Satoko Arakawa, Alifu Yikelamu, Mizuki Kusaba, Satoshi Kofuji, Hiroshi Nishina, Munetaka Ishiyama, Yuichiro Ueno, Shigeomi Shimizu: Development of small fluorescent probes for the analysis of autophagy kinetics. iScience. 2023.07; 26 (7): 107218. ( PubMed , DOI )

  19. Kawamoto S, Uemura K, Hori N, Takayasu L, Konishi Y, Katoh K, Matsumoto T, Suzuki M, Sakai Y, Matsudaira T, Adachi T, Ohtani N, Standley DM, Suda W, Fukuda S, Hara E: Bacterial induction of B cell senescence promotes age-related changes in the gut microbiota. Nature cell biology. 2023.06; 25 (6): 865-876. ( PubMed , DOI )

  20. Kenta Iitani, Hidehisa Mori, Kenta Ichikawa, Koji Toma, Takahiro Arakawa, Yasuhiko Iwasaki, Kohiji Mitsubayashi: Gas-Phase Biosensors (Bio-Sniffers) for Measurement of 2-Nonenal, the Causative Volatile Molecule of Human Aging-Related Body Odor Sensors. 2023.06; 23 (13): 5857. ( DOI )

  21. Noriyuki Azuma, Tadashi Yokoi, Taku Tanaka, Emiko Matsuzaka, Yuki Saida, Sachiko Nishina, Miho Terao, Shuji Takada, Maki Fukami, Kohji Okamura, Kayoko Maehara, Tokiwa Yamasaki, Jun Hirayama, Hiroshi Nishina, Hiroshi Handa, Yuki Yamaguchi: Integrator complex subunit 15 controls mRNA splicing and is critical for eye development. Hum Mol Genet. 2023.06; 32 (12): 2032-2045. ( PubMed , DOI )

  22. Hidekazu Matsumoto, Keisuke Tomoto, Gentaro Kawase, Kenta Iitani, Koji Toma, Takahiro Arakawa, Kohiji Mitsubayashi, Keiji Moriyama: Real-time Continuous Monitoring of Oral Soft Tissue Pressure with a Wireless Mouthguard Device for Assessing Tongue Thursting Habits Sensors. 2023.05; 23 (11): 5027. ( DOI )

  23. Zhang Z, Niwa T, Watanabe K, Hosoya T: #U11#URC-Cyanation of Aryl Fluorides via Nickel and Lithium Chloride-Mediated C-F Bond Activation. Angew Chem Int Ed Engl. 2023.05; 62 (22): e202302956. ( PubMed , DOI )

  24. Goto Toshiyasu, Michiue Tatsuo, Shibuya Hiroshi: ccl19 and ccl21 affect cell movements and differentiation in early Xenopus development DEVELOPMENT GROWTH & DIFFERENTIATION. 2023.04; 65 (3): 175-189. ( PubMed , DOI )

  25. Kenta Iitani, Kanako Kishima, Yuka Kasuga, Kumi Yokota, Hiroki Nitta, Kohki Onchi, Gentaro Kawase, Kouta Umezawa, Koji Toma, Takahiro Arakawa, Dzung Viet Dao, Kohji Mitsubayashi: Wireless Unconstrained Monitoring of Intra-oral Temperature Using Thermistor and Telemeter Sealed in Mouthguard Sensors and Materials. 2023.04; 35 (4): 1315-1325. ( DOI )

  26. Aiko Watanabe, Hiroyuki Koike, Naoki Kumagami, Shigeki Shimba, Ichiro Manabe, Yumiko Oishi: Arntl deficiency in myeloid cells reduces neutrophil recruitment and delays skeletal muscle repair. Scientific Reports. 2023.04; 13 (1): 6747. ( PubMed , DOI )

  27. Yuki Yoshimoto, Yumiko Oishi: Mechanisms of skeletal muscle-tendon development and regeneration/healing as potential therapeutic targets. Pharmacol Ther. 2023.03; 243 108357. ( PubMed , DOI )

  28. Niwa T, Tahara T, Chase CE, Fang FG, Nakaoka T, Irie S, Hayashinaka E, Wada Y, Mukai H, Masutomi K, Watanabe Y, Cui Y, Hosoya T: Synthesis of #U11#URC-Radiolabeled Eribulin as a Companion Diagnostics PET Tracer for Brain Glioblastoma. Bull Chem Soc Jpn. 2023.03; 96 (3): 283-290. ( DOI )

  29. Dubol M, Immenschuh J, Jonasson M, Takahashi K, Niwa T, Hosoya T, Roslin S, Wikström J, Antoni G, Watanabe Y, Lubberink M, Biegon A, Sundström-Poromaa I, Comasco E: Acute nicotine exposure blocks aromatase in the limbic brain of healthy women: A [#U11#URC]cetrozole PET study. Compr Psychiatry. 2023.03; 123 152381. ( PubMed , DOI )

  30. Kohei Tsuji, Kofi Baffour-Awuah Owusu, Yutaro Miura, Takahiro Ishii, Kouki Shinohara, Takuya Kobayakawa, Akino Emi, Takashi Nakano, Youichi Suzuki, Hirokazu Tamamura : Dimerized fusion inhibitor peptides targeting the HR1–HR2 interaction of SARS-CoV-2 RSC Advances. 2023.03; 13 8779-8793.

  31. Koji Toma, Yui Satomura, Kenta Iitani, Takahiro Arakawa, Kohji Mitsubayashi: Long-range surface plasmon aptasensor for label-free monitoring of vancomycin Biosensors and Bioelectronics. 2023.02; 222 114959. ( DOI )

  32. Sakata Y, Nabekura R, Hazama Y, Hanya M, Nishiyama T, Kii I, Hosoya T: Synthesis of Functionalized Dibenzoazacyclooctynes by a Decomplexation Method for Dibenzo-Fused Cyclooctyne-Cobalt Complexes. Org Lett. 2023.02; 25 (7): 1051-1055. ( PubMed , DOI )

  33. Tabata S, Minoshima M, Kobayashi A, Matsuzawa T, Hosoya T, Yoshida S: Migrative Thioamination of Aryne Intermediates Generated from #Io#IR-Iodoaryl Triflates. Synlett. 2023.02; ( DOI )

  34. Higashi-Kuwata N, Tsuji K, Hayashi H, Bulut H, Kiso M, Imai M, Ogata-Aoki H, Ishii T, Kobayakawa T, Nakano K, Takamune N, Kishimoto N, Hattori SI, Das D, Uemura Y, Shimizu Y, Aoki M, Hasegawa K, Suzuki S, Nishiyama A, Saruwatari J, Shimizu Y, Sukenaga Y, Takamatsu Y, Tsuchiya K, Maeda K, Yoshimura K, Iida S, Ozono S, Suzuki T, Okamura T, Misumi S, Kawaoka Y, Tamamura H, Mitsuya H: Identification of SARS-CoV-2 M(pro) inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2. Nature communications. 2023.02; 14 (1): 1076. ( PubMed , DOI )

  35. Caspase-11 contributes to site-1 protease cleavage and SREBP1 activation in the inflammatory response of macrophages 2023.01; 14 1009973. ( PubMed , DOI )

  36. Kobayashi A, Matsuzawa T, Hosoya T, Yoshida S: Synthesis of benzo[#Ib#IR]furans from alkynyl sulfoxides and phenols by the interrupted Pummerer reaction. RSC Adv. 2023.01; 13 (2): 839-843. ( PubMed , DOI )

  1. Cyclic stretch regulates immune responses via tank‐binding kinase 1 expression in macrophages 2022.12; 13 (1): 185-194. ( PubMed , DOI )

  2. Wen-Jin Ho, Mako Kobayashi, Kozue Murata, Yoshihide Hashimoto, Kenji Izumi, Tsuyoshi Kimura, Hideo Kanemitsu, Kazuhiro Yamazaki, Tadashi Ikeda, Kenji Minatoya, Akio Kishida, Hidetoshi Masumoto: A novel approach for the endothelialization of xenogeneic decellularized vascular tissues by human cells utilizing surface modification and dynamic culture. Scientific Reports. 2022.12; 12 (1): 22294. ( PubMed , DOI )

  3. Matsumoto K, Kuwata T, Tolbert WD, Richard J, Ding S, Prévost J, Takahama S, Judicate GP, Ueno T, Nakata H, Kobayakawa T, Tsuji K, Tamamura H, Smith AB 3rd, Pazgier M, Finzi A, Matsushita S: Characterization of a Novel CD4 Mimetic Compound YIR-821 against HIV-1 Clinical Isolates. Journal of virology. 2022.12; 97 (1): e0163822. ( PubMed , DOI )

  4. Hall D, Basu G, Ito N: Computational biophysics and structural biology of proteins-a Special Issue in honor of Prof. Haruki Nakamura's 70th birthday. Biophysical reviews. 2022.12; 14 (6): 1211-1222. ( PubMed , DOI )

  5. Goto Toshiyasu, Shibuya Hiroshi: maea affects head formation through beta-catenin degradation during early Xenopus laevis development DEVELOPMENT GROWTH & DIFFERENTIATION. 2022.12; ( PubMed , DOI )

  6. Rongyi Wang, Kohei Tsuji, Takuya Kobayakawa, Yishan Liu, Kazuhisa Yoshimura, Shuzo Matsushita, Shigeyoshi Harada, Hirokazu Tamamura: Hybrids of small CD4 mimics and gp41-related peptides as dual-target HIV entry inhibitors Bioorganic & Medicinal Chemistry. 2022.12; 76 117083. ( PubMed , DOI )

  7. Matsuura K, Yamaura M, Sakawaki H, Himeno A, Pisil Y, Kobayakawa T, Tsuji K, Tamamura H, Matsushita S, Miura T: Sensitivity to a CD4 mimic of a consensus clone of monkey-adapted CCR5-tropic SHIV-MK38C. Virology. 2022.12; 578 171-179. ( PubMed , DOI )

  8. Oda C, Kamimura K, Shibata O, Morita S, Tanaka Y, Setsu T, Abe H, Yokoo T, Sakamaki A, Kamimura H, Kofuji S, Wakai T, Nishina H, Terai S: HBx and YAP expression could promote tumor development and progression in HBV-related hepatocellular carcinoma. Biochemistry and biophysics reports. 2022.12; 32 101352. ( PubMed , DOI )

  9. Depletion of CD206+ M2-like macrophages induces fibro-adipogenic progenitors activation and muscle regeneration 2022.11; 13 (1): 7058. ( PubMed , DOI )

  10. Hiroyuki Koike, Ichiro Manabe, Yumiko Oishi: Mechanisms of cooperative cell-cell interactions in skeletal muscle regeneration. Inflammation and Regeneration. 2022.11; 42 (1): 48. ( PubMed , DOI , 医中誌 )

  11. Sakurako Kobayashi, Nobuhiko Ogasawara, Satoshi Watanabe, Yosuke Yoneyama, Sakura Kirino, Yui Hiraguri, Masami Inoue, Sayaka Nagata, Yoshimi Okamoto-Uchida, Satoshi Kofuji, Hiromichi Shimizu, Go Ito, Tomohiro Mizutani, Shinichi Yamauchi, Yusuke Kinugasa, Yoshihito Kano, Yasuhiro Nemoto, Mamoru Watanabe, Kiichiro Tsuchiya, Hiroshi Nishina, Ryuichi Okamoto, Shiro Yui: Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation. Inflamm Regen. 2022.11; 42 (1): 49. ( PubMed , DOI )

  12. Tsuji K, Ishii T, Kobayakawa T, Higashi-Kuwata N, Azuma C, Nakayama M, Onishi T, Nakano H, Wada N, Hori M, Shinohara K, Miura Y, Kawada T, Hayashi H, Hattori SI, Bulut H, Das D, Takamune N, Kishimoto N, Saruwatari J, Okamura T, Nakano K, Misumi S, Mitsuya H, Tamamura H: Potent and biostable inhibitors of the main protease of SARS-CoV-2. iScience. 2022.11; 105365. ( PubMed , DOI )

  13. Koike Hiroyuki, Manabe Ichiro, Oishi Yumiko: 骨格筋再生における協調的細胞間相互作用のメカニズム(Mechanisms of cooperative cell-cell interactions in skeletal muscle regeneration) Inflammation and Regeneration. 2022.11; 42 1 of 11-11 of 11. ( 医中誌 )

  14. Koji Toma, Koki Oishi, Kenta Iitani, Arakawa Takahiro, Kohji Mitsubayashi: Surface plasmon-enhanced fluorescence immunosensor for monitoring cardiac troponin I Sensors and Actuators B: Chemical. 2022.10; 368 132132. ( DOI )

  15. Kenta Iitani, Misa Nakaya, Tsubomi Tomono, Koji Toma, Takahiro Arakawa, Yuji Tsuchido, Kohji Mitsubayashi, Naoya Takeda: Enzyme-embedded electrospun fiber sensor of hydrophilic polymer for fluorometric ethanol gas imaging in vapor phase Biosensors and Bioelectronics. 2022.10; 213 114453. ( DOI )

  16. Tomoko Gessei, Akira Monkawa, Takahiro Arakawa, Kohji Mitsubayashi: Blood sorbitol measurement in diabetic rats treated with an aldose reductase inhibitor using an improved fiber-optic sorbitol biosensor Talanta. 2022.10; 248 123595. ( DOI )

  17. Katayama A, Jin Y, Nishiyama Y, Hosoya T, Yokoshima S: Substitution of α-Azido Sulfones with Thiolates to Form α-Azido Sulfides. Org Lett. 2022.10; 24 (40): 7361-7365. ( PubMed , DOI )

  18. Takeuchi Y, Fukunaga M, Iwatani S, Miyanaga K, Adachi T, Yamamoto N: Release of an anti-anxiety peptide in casein hydrolysate with Aspergillus oryzae protease. Food & function. 2022.10; 13 (20): 10449-10460. ( PubMed , DOI )

  19. Kohji Mitsubayashi, Koji Toma, Kenta Iitani, Takahiro Arakawa: Gas-phase biosensors: a review Sensors and Actuators B: Chemical. 2022.09; 367 132053. ( DOI )

  20. Takahiro Arakawa, Riki Ishikawa, Kenta Iitani, Koji Toma, Yasuhiko Iwasaki, Kohji Mitsubayashi: Headset bio-sniffer with wireless CMOS camera for percutaneous ethanol vapor from the ear canal Biosensors and Bioelectronics:X. 2022.09; 11 100169. ( DOI )

  21. Anri Koyanagi, Iichiroh Onishi, Karin Muraoka, Ikue Sato, Shingo Sato, Tsuyoshi Kimura, Akio Kishida, Kouhei Yamamoto, Masanobu Kitagawa, Morito Kurata: Identification of the factor that leads human mesenchymal stem cell lines into decellularized bone Bioengineering (Basel). 2022.09; 9 (10): 490. ( PubMed , DOI )

  22. Mika Suzuki, Tsuyoshi Kimura, Yuta Nakano, Mako Kobayashi, Masahiro Okada, Takuya Matsumoto, Yoshihide Hashimoto, Akio Kishida: Preparation of mineralized pericardium by alternative soaking for soft–hard interregional tissue application Journal of Biomedical Materials Research Part A. 2022.09; 1 1-11. ( DOI )

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  25. Mako Kobayashi, Naoki Ishida, Yoshihide Hashimoto, Jun Negishi, Hideki Saga, Yoshihiro Sasaki, Kazunari Akiyoshi, Tsuyoshi Kimura, Akio Kishida: Extraction and biological evaluation of atrix-bound nanovesicles (MBVs) from high-hydrostatic pressure-decellularized tissues. International Journal of Molecular Science. 2022.08; 23 (16): 8868. ( PubMed , DOI )

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  36. Sugiyama K, Sakata Y, Niwa T, Yoshida S, Hosoya T: Azido-type-selective triazole formation by iridium-catalyzed cycloaddition with thioalkynes. Chem Commun. 2022.05; 58 (42): 6235-6238. ( PubMed , DOI )

  37. Hirata Y, Nomura K, Kato D, Tachibana Y, Niikura T, Uchiyama K, Hosooka T, Fukui T, Oe K, Kuroda R, Hara Y, Adachi T, Shibasaki K, Wake H, Ogawa W: A Piezo1/KLF15/IL-6 axis mediates immobilization-induced muscle atrophy. The Journal of clinical investigation. 2022.05; 132 (10): 1-13. ( PubMed , DOI )

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  57. Shoko Miyata, Noriaki Saku, Saeko Akiyama, Palaksha Kanive Javaregowda, Kenta Ite, Nagisa Takashima, Masashi Toyoda, Kei Yura, Tohru Kimura, Hiroshi Nishina, Atsuko Nakazawa, Mureo Kasahara, Hidenori Nonaka, Tohru Kiyono, Akihiro Umezawa: Puromycin-based purification of cells with high expression of the cytochrome P450 CYP3A4 gene from a patient with drug-induced liver injury (DILI). Stem Cell Res Ther. 2022.01; 13 (1): 6. ( PubMed , DOI )

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  65. Narintadeach Charoensombut, Kinyoshi Kawabata, Jeonghyun Kim, Minki Chang, Tsuyoshi Kimura, Akio Kishida, Takashi Ushida, Katsuko S Furukawa: Internal radial perfusion bioreactor promotes decellularization and recellularization of rat uterine tissue Journal of Bioscience and Bioengineering. 2022.01; 133 (1): 83-88. ( DOI )

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  33. Yosuke Inoue, Yuya Hanazono, Kentaro Noi, Akihiro Kawamoto, Masato Kimatsuka, Ryuhei Harada, Kazuki Takeda, Ryoichi Kita, Natsuki Iwamasa, Kyoka Shibata, Keiichi Noguchi, Yasuteru Shigeta, Keiichi Namba, Teru Ogura, Kunio Miki, Kyosuke Shinohara, Masafumi Yohda: Split conformation of Chaetomium thermophilum Hsp104 disaggregase. Structure. 2021.07; 29 (7): 721-730. ( PubMed , DOI )

  34. 荒川 貴博, 三林 浩二: 生体ガス計測用バイオスニファとイメージングシステム ガステックニュース. 2021.07; 116 1-2.

  35. Toma K, Iwasaki K, Zhang G, Iitani K, Arakawa T, Iwasaki Y, Mitsubayashi K: Biochemical Methanol Gas Sensor (MeOH Bio-Sniffer) for Non-Invasive Assessment of Intestinal Flora from Breath Methanol. Sensors (Basel, Switzerland). 2021.07; 21 (14): ( PubMed , DOI )

  36. Takako Ooshio, Masahiro Yamamoto, Kiyonaga Fujii, Bing Xin, Kenji Watanabe, Masanori Goto, Yoko Okada, Akira Suzuki, Josef M Penninger, Hiroshi Nishina, Yuji Nishikawa: Hepatocyte Mitogen-Activated Protein Kinase Kinase 7 Contributes to Restoration of the Liver Parenchyma Following Injury in Mice. Hepatology. 2021.06; 73 (6): 2510-2526. ( PubMed , DOI )

  37. Kobayashi K, Matsuzawa T, Hosoya T, Yoshida S: Thioxanthone Synthesis from Benzoic Acid Esters through Directed #Iortho#IR-Lithiation. Chem Lett. 2021.06; 50 (9): 1624-1627. ( DOI )

  38. Aimi T, Meguro T, Kobayashi A, Hosoya T, Yoshida S: Nucleophilic transformations of azido-containing carbonyl compounds via protection of the azido group. Chem Commun. 2021.06; 57 (49): 6062-6065. ( PubMed , DOI )

  39. Toma K, Suzuki S, Arakawa T, Iwasaki Y, Mitsubayashi K: External ears for non-invasive and stable monitoring of volatile organic compounds in human blood. Scientific reports. 2021.06; 11 (1): 10415. ( PubMed , DOI )

  40. Nagaishi T, Watabe T, Kotake K, Kumazawa T, Aida T, Tanaka K, Ono R, Ishino F, Usami T, Miura T, Hirakata S, Kawasaki H, Tsugawa N, Yamada D, Hirayama K, Yoshikawa S, Karasuyama H, Okamoto R, Watanabe M, Blumberg RS, Adachi T: Immunoglobulin A-specific deficiency induces spontaneous inflammation specifically in the ileum. Gut. 2021.05; 71 (3): 487-496. ( PubMed , DOI )

  41. Mako Kobayashi, Masako Ohara, Yoshihide Hashimoto, Naoko Nakamura, Toshiya Fujisato, Tsuyoshi Kimura, Akio Kishida: Effect of luminal surface structure of decellularized aorta on thrombus formation and cell behavior PLoS One. 2021.05; 16 (5): e0246221. ( DOI )

  42. Kobayashi T, Hosoya T, Yoshida S: Facile Synthetic Methods for Diverse #IN#IR-Arylphenylalanine Derivatives via Transformations of Aryne Intermediates and Cross-Coupling Reactions. Bull Chem Soc Jpn. 2021.05; 94 (7): 1823-1832. ( DOI )

  43. Jan Vincent V. Arafiles, Hisaaki Hirose, Yusuke Hirai, Masashi Kuriyama, Maxwell Mamfe Sakyiamah, Wataru Nomura, Kazuhiro Sonomura, Miki Imanishi, Akira Otaka, Hirokazu Tamamura & Shiroh Futaki: Discovery of a Macropinocytosis-inducing Peptide Potentiated by Medium-mediated Intramolecular Disulfide Formation. Angewandte Chemie International Edition. 2021.05; 60 (21): 11928-11936.

  44. Yoshida S, Hosoya T: Recent Insertion Reactions of Aryne Intermediates. Modern Aryne Chemistry (Ed. Biju AT). 2021.05; 111-148. ( DOI )

  45. Nagashima S, Maruyama J, Honda K, Kondoh Y, Osada H, Nawa M, Nakahama KI, Ishigami-Yuasa M, Kagechika H, Sugimura H, Iwasa H, Arimoto-Matsuzaki K, Nishina H, Hata Y: CSE1L promotes nuclear accumulation of transcriptional coactivator TAZ and enhances invasiveness of human cancer cells. The Journal of biological chemistry. 2021.05; 297 (1): 100803. ( PubMed , DOI )

  46. Kubotera T, Oishi T, Toma K, Arakawa T, Mitsubayashi K: 唾液尿酸計測のためのBluetooth low energy無線通信式マウスピース型バイオセンサの開発 Journal of Advanced Science. 2021.04; 33 33301-1-33301-3. ( DOI )

  47. Iwasaki Toshio, Miyajima-Nakano Yoshiharu, Fukazawa Risako, Lin Myat T., Matsushita Shin-ichi, Hagiuda Emi, Taguchi Alexander T., Dikanov Sergei A., Oishi Yumiko, Gennis Robert B.: 蛋白質の構造機能相関を調査するための大腸菌アミノ酸要求性発現宿主株(Escherichia coli amino acid auxotrophic expression host strains for investigating protein structure-function relationships) The Journal of Biochemistry. 2021.04; 169 (4): 387-394. ( 医中誌 )

  48. Nakajima H, Hazama Y, Sakata Y, Uchida K, Hosoya T, Yoshida S: Diverse diaryl sulfide synthesis through consecutive aryne reactions. Chem Commun. 2021.03; 57 (21): 2621-2624. ( PubMed , DOI )

  49. Matsuzawa T, Hosoya T, Yoshida S: Transition-Metal-Free Synthesis of #IN#IR-Arylphenothiazines through an #IN#IR- and #IS#IR-Arylation Sequence. Org Lett. 2021.03; 23 (6): 2347-2352. ( PubMed , DOI )

  50. Minoshima M, Uchida K, Nakamura Y, Hosoya T, Yoshida S: Acylalkylation of Arynes Generated from #Io#IR-Iodoaryl Triflates with Hydrosilanes and Cesium Fluoride. Org Lett. 2021.03; 23 (5): 1868-1873. ( PubMed , DOI )

  51. Suzuki M, Kanemoto K, Nakamura Y, Hosoya T, Yoshida S: Palladium-Catalyzed Sulfinylation of Aryl- and Alkenylborons with Sulfinate Esters. Org Lett. 2021.03; 23 (9): 3793-3797. ( PubMed , DOI )

  52. Takuya Kobayakawa, Chika Azuma, Yuki Watanabe, Shunsuke Sawamura, Atsuhiko Taniguchi, Yoshio Hayashi, Kohei Tsuji & Hirokazu Tamamura: Development of Methods for Convergent Synthesis of Chloroalkene Dipeptide Isosteres and Its Application. The Journal of Organic Chemistry. 2021.03; 86 (7): 5091-5101. ( PubMed , DOI )

  53. Yokoi Y, Adachi T, Sugimoto R, Kikuchi M, Ayabe T, Nakamura K: Simultaneous real-time analysis of Paneth cell and intestinal stem cell response to interferon-γ by a novel stem cell niche tracking method. Biochemical and biophysical research communications. 2021.03; 545 14-19. ( PubMed , DOI )

  54. Toma K, Iwasaki K, Arakawa T, Iwasaki Y, Mitsubayashi K: Sensitive and selective methanol biosensor using two-enzyme cascade reaction and fluorometry for non-invasive assessment of intestinal bacteria activity. Biosensors & bioelectronics. 2021.03; 181 113136. ( PubMed , DOI )

  55. Toyomoto M, Inoue A, Iida K, Denawa M, Kii I, Kadj F M N, Kishi T, Im D, Shimamura T, Onogi H, Yoshida S, Iwata S, Aoki J, Hosoya T, Hagiwara M: S1PR3–G#D12#DR-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation. Cell Chem Biol. 2021.02; 28 (8): 1132-1144. ( PubMed , DOI )

  56. Xinliang Jiang, Junichi Maruyama, Hiroaki Iwasa, Kyoko Arimoto-Matsuzaki, Hiroshi Nishina, Yutaka Hata: Heat shock induces the nuclear accumulation of YAP1 via SRC. Exp Cell Res. 2021.02; 399 (1): 112439. ( PubMed , DOI )

  57. Takuya Kobayakawa, Masaru Yokoyama, Kohei Tsuji, Masayuki Fujino, Masaki Kurakami, Sayaka Boku, Miyuki Nakayama, Moemi Kaneko, Nami Ohashi, Osamu Kotani, Tsutomu Murakami, Hironori Sato & Hirokazu Tamamura: Small-Molecule Anti-HIV-1 Agents Based on HIV-1 Capsid Proteins. Biomolecules. 2021.02; 11 (2): 208. ( PubMed , DOI )

  58. Senga Akane, Numoto Nobutaka, Yamashita Mitsuaki, Iida Akira, Ito Nobutoshi, Kawai Fusako, Oda Masayuki: Multiple structural states of Ca2+-regulated PET hydrolase, Cut190, and its correlation with activity and stability The Journal of Biochemistry. 2021.02; 169 (2): 207-213. ( 医中誌 )

  59. Toma K, Tsujii M, Arakawa T, Mitsubayashi K: Dual-target gas-phase biosensor (bio-sniffer) for assessment of lipid metabolism from breath acetone and isopropanol Sensors and Actuators B: Chemical. 2021.02; 329 129260. ( DOI )

  60. Takuya Kobayakawa, Kohei Tsuji, Kiju Konno, Ai Himeno, Ami Masuda, Tingting Yang, Kohei Takahashi, Yusuke Ishida, Nami Ohashi, Takeo Kuwata, Kaho Matsumoto, Kazuhisa Yoshimura, Hiromi Sakawaki, Tomoyuki Miura, Shigeyoshi Harada, Shuzo Matsushita & Hirokazu Tamamura: Hybrids of Small-Molecule CD4 Mimics with Polyethylene Glycol Units as HIV Entry Inhibitors. Journal of Medicinal Chemistry. 2021.01; 64 (3): 1481-1496. ( PubMed , DOI )

  61. Plasma and follicular fluid osteopontin levels during ovarian cycle and their correlation with follicular fluid vascular endothelial growth factor levels. 2021.01; 11 (1): 286. ( PubMed , DOI )

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  65. Tadashi Shin, Yuichi Hiraoka, Tokiwa Yamasaki, Jamey D Marth, Josef M Penninger, Masami Kanai-Azuma, Kohichi Tanaka, Satoshi Kofuji, Hiroshi Nishina: MKK7 deficiency in mature neurons impairs parental behavior in mice. Genes Cells. 2021.01; 26 (1): 5-17. ( PubMed , DOI )

  66. Koji Toma, Chisato Kishikawa, Takahiro Arakawa, Kohji Mitsubayashi: Reusable surface plasmon resonance immunosensor for temporal information of protein biomarkers Sensors and Materials. 2021.01; 33 251-260. ( DOI )

  67. Endo R, Uchiyama K, Lim SY, Itakura M, Adachi T, Uchida K: Recognition of acrolein-specific epitopes by B cell receptors triggers an innate immune response. The Journal of biological chemistry. 2021.01; 296 100648. ( PubMed , DOI )

  68. Isoda M, Uetake Y, Takimoto T, Tsuda J, Hosoya T, Niwa T: Convergent Synthesis of Fluoroalkenes Using a Dual-Reactive Unit. J Org Chem. 2021.01; 86 (2): 1622-1632. ( PubMed , DOI )

  69. Yoshida S, Sakata Y, Misawa Y, Morita T, Kuribara T, Ito H, Koike Y, Kii I, Hosoya T: Assembly of four modules onto a tetraazide platform by consecutive 1,2,3-triazole formations. Chem Commun. 2021.01; 57 (7): 899-902. ( PubMed , DOI )

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  71. Kohei Tsuji, Rongyi Wang, Takuya Kobayakawa, Kofi Baffour-Awuah Owusu, Masayuki Fujino, Moemi Kaneko, Naoki Yamamoto, Tsutomu Murakami, Hirokazu Tamamura: Potent leads based on CA-19L, an anti-HIV active HIV-1 capsid fragment. Bioorganic & Medicinal Chemistry. 2021.01; 30 115923. ( PubMed , DOI )

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  1. Mako Kobayashi, Masao Ohara, Yoshihide Hashimoto, Naoko Nakamura, Toshiya Fujisato, Tsuyoshi Kimura, Akio Kishida: In vitro evaluation of surface biological properties of decellularized cardiovascular use J. Mater. Chem. B. 2020.12; 2020 (48): 10977-10989. ( DOI )

  2. Kotaro Yanagisawa, Seiichi Funamoto, Yoshihide Hashimoto, Jun Negishi: Introduction of cells into porous Poly (L-lactic) acid scaffolds using impregnation techniques Tissue Eng Part C: Methods. 2020.12; 26 (12): 608-616. ( DOI )

  3. Takuya Kobayakawa, Kento Ebihara, Kohei Tsuji, Takuma Kawada, Masayuki Fujino, Yuzuna Honda, Nami Ohashi, Tsutomu Murakami, Hirokazu Tamamura: Bivalent HIV-1 fusion inhibitors based on peptidomimetics. Bioorg. Med. Chem. 2020.12; 28 (24): 115812. ( PubMed , DOI )

  4. Masaki Watanabe, Hanako Maeda, Yoshihide Hashimoto, Tsuyoshi Kimura, Akio Kishida: Protein adsorption and cell adhension behavior of engineering plastics plasticized by supercritical carbon dioxide Dent. Mater. J. 2020.12; 39 (6): 1033-1038. ( DOI )

  5. Iiyama M, Numoto N, Ogawa S, Kuroda M, Morii H, Abe R, Ito N, Oda M: Molecular interactions of the CTLA-4 cytoplasmic region with the phosphoinositide 3-kinase SH2 domains. Molecular immunology. 2020.12; 131 51-59. ( PubMed , DOI )

  6. Emori Miho, Numoto Nobutaka, Senga Akane, Bekker Gert-Jan, Kamiya Narutoshi, Kobayashi Yuma, Ito Nobutoshi, Kawai Fusako, Oda Masayuki: Structural basis of mutants of PET-degrading enzyme from Saccharomonospora viridis AHK190 with high activity and thermal stability PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 2020.12; 89 (5): 502-511. ( PubMed , DOI )

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  8. Takemura H, Goto S, Hosoya T, Yoshida S: 2-Azidoacrylamides as compact platforms for efficient modular synthesis. Chem Commun (Camb). 2020.12; 56 (99): 15541-15544. ( PubMed , DOI )

  9. Idogawa R, Kim Y, Shimomori K, Hosoya T, Yoshida S: Single C–F Transformations of #Io#IR-Hydrosilyl Benzotrifluorides with Trityl Compounds as All-in-One Reagents. Org Lett. 2020.12; 22 (23): 9292-9297. ( PubMed , DOI )

  10. Higuchi Tadashi, Yamaguchi Fumio, Asakura Takayuki, Yoshida Daizo, Oishi Yumiko, Morita Akio: 超音波は神経膠腫細胞において蛍光強度とアミノレブリン酸に対するABCG2 mRNA反応を調節する(Ultrasound Modulates Fluorescence Strength and ABCG2 mRNA Response to Aminolevulinic Acid in Glioma Cells) Journal of Nippon Medical School. 2020.12; 87 (6): 310-317. ( 医中誌 )

  11. Tanaka Miyako, Saka-Tanaka Marie, Ochi Kozue, Fujieda Kumiko, Sugiura Yuki, Miyamoto Tomofumi, Kohda Hiro, Ito Ayaka, Miyazawa Taiki, Matsumoto Akira, Aoe Seiichiro, Miyamoto Yoshihiro, Tsuboi Naotake, Maruyama Shoichi, Suematsu Makoto, Yamasaki Sho, Ogawa Yoshihiro, Suganami Takayoshi: C-type lectin Mincle mediates cell death-triggered inflammation in acute kidney injury JOURNAL OF EXPERIMENTAL MEDICINE. 2020.11; 217 (11): ( PubMed , DOI )

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  14. Sato Atsushi, Shimizu Masahiro, Goto Toshiyasu, Masuno Hiroyuki, Kagechika Hiroyuki, Tanaka Nobuyuki, Shibuya Hiroshi: WNK regulates Wnt signalling and beta-Catenin levels by interfering with the interaction between beta-Catenin and GID COMMUNICATIONS BIOLOGY. 2020.11; 3 (1): ( DOI )

  15. Chien PJ, Suzuki T, Ye M, Toma K, Arakawa T, Iwasaki Y, Mitsubayashi K: Ultra-Sensitive Isopropanol Biochemical Gas Sensor (Bio-Sniffer) for Monitoring of Human Volatiles. Sensors (Basel, Switzerland). 2020.11; 20 (23): ( PubMed , DOI )

  16. Terashima N, Sakata Y, Meguro T, Hosoya T, Yoshida S: Triazole formation of phosphinyl alkynes with azides through transient protection of phosphine by copper. Chem Commun (Camb). 2020.11; 56 (90): 14003-14006. ( PubMed , DOI )

  17. Nakano-Kobayashi A, Fukumoto A, Morizane A, Nguyen D T , Le T M, Hashida K, Hosoya T, Takahashi R, Takahashi J, Hori O, Hagiwara M: Therapeutics potentiating microglial p21-Nrf2 axis can rescue neurodegeneration caused by neuroinflammation. Sci Adv. 2020.11; 6 (46): eabc1428. ( PubMed , DOI )

  18. Matsuzawa T, Hosoya T, Yoshida S: One-step synthesis of benzo[#Ib#IR]thiophenes by aryne reaction with alkynyl sulfides. Chem Sci. 2020.11; 11 (35): 9691-9696. ( DOI )

  19. Jonasson M, Nordeman P, Eriksson J, Wilking H, Wikström J, Takahashi K, Niwa T, Hosoya T, Watanabe Y, Antoni G, Sundström Poromaa I, Lubberink M, Comasco E: Quantification of aromatase binding in the female human brain using [#U11#URC]cetrozole positron emission tomography. J Neurosci Res. 2020.11; 98 (11): 2208-2218. ( PubMed , DOI )

  20. Po-Jen Chien, Takuma Suzuki, Ming Ye, Koji Toma, Takahiro Arakawa, Yasuhiko Iwasaki, Kohji Mitsubayashi: Ultra-Sensitive Isopropanol Biochemical Gas Sensor (Bio-Sniffer) for Monitoring of Human Volatiles Sensors. 2020.11; 20 (23): 6827. ( DOI )

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  22. Nakamura Y, Sakata Y, Hosoya T, Yoshida S: Synthesis of Functionalized Benzopyran/Coumarin-Derived Aryne Precursors and Their Applications. Org Lett. 2020.10; 22 (21): 8505-8510. ( PubMed , DOI )

  23. Naoko Nakamura, Kazuki Saito, Tsuyoshi Kimura, Akio Kishida: Recellularization of decellularized cancellous bone scaffolds using low temperature cell seeding Tissue and Cell. 2020.10; 66 101385. ( DOI )

  24. Daisuke Matsumoto, Hirokazu Tamamura, Wataru Nomura: A cell cycle-dependent CRISPR-Cas9 activation system based on an anti-CRISPR protein shows improved genome editing accuracy Communications Biology. 2020.10; 3 1-10. ( PubMed , DOI )

  25. Osawa Shigehito, Matsumoto Akira, Maejima Yukie, Suzuki Toshihiro, Miyahara Yuji, Otsuka Hidenori: Direct Observation of Cell Surface Sialylation by Atomic Force Microscopy Employing Boronic Acid-Sialic Acid Reversible Interaction ANALYTICAL CHEMISTRY. 2020.09; 92 (17): 11714-11720. ( PubMed , DOI )

  26. Kitazawa M, Hayashi S, Imamura M, Takeda S, Oishi Y, Kaneko-Ishino T, Ishino F: Deficiency and overexpression of Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Kagami-Ogata syndromes. Development (Cambridge, England). 2020.09; 147 (21): ( PubMed , DOI )

  27. Senga A, Numoto N, Yamashita M, Iida A, Ito N, Kawai F, Oda M: Multiple structural states of Ca2+ regulated PET hydrolase, Cut190, and its correlation with activity and stability. Journal of biochemistry. 2020.09; 169 (2): 207-213. ( PubMed , DOI )

  28. Kohei Tsuji, David Hymel, Terrence R. Burke, Jr.: A new genre of fluorescence recovery assay to evaluate polo-like kinase 1 ATP-competitive inhibitors. Anal. Methods: advancing methods and applications. 2020.09; 12 (36): 4418-4421. ( PubMed , DOI )

  29. Arakawa T, Tomoto K, Nitta H, Toma K, Takeuchi S, Sekita T, Minakuchi S, Mitsubayashi K: A Wearable Cellulose Acetate-Coated Mouthguard Biosensor for In Vivo Salivary Glucose Measurement. Analytical chemistry. 2020.09; 92 (18): 12201-12207. ( PubMed , DOI )

  30. Mako Kobayashi, Junpei Kadota, Yoshihide Hashimoto, Toshiya Fujisato, Naoko Nakamura, Tsuyoshi Kimura, Akio Kishida: Elastic modulus of ECM hydrogels derived from decellularized tissue affects capillary network formation in endothelial cells Int. J. Mol. Sci. 2020.09; 21 (17): 6304. ( DOI )

  31. Makio N, Sakata Y, Kuribara T, Adachi K, Hatakeyama Y, Meguro T, Igawa K, Tomooka K, Hosoya T, Yoshida S: (Hexafluoroacetylacetonato)copper(I)-cycloalkyne complexes as protected cycloalkynes. Chem Commun (Camb). 2020.09; 56 (77): 11449-11452. ( PubMed , DOI )

  32. Sato Y, Miyamoto Y, Sumida Y, Hosoya T, Ohmiya H: Boracene-based alkylborate enabled Ni/Ir hybrid catalysis. Org Biomol Chem. 2020.09; 18 (34): 6598-6601. ( PubMed , DOI )

  33. Ikeda M, Matsuzawa T, Morita T, Hosoya T, Yoshida S: Synthesis of Diverse Aromatic Ketones through C-F Cleavage of Trifluoromethyl Group. Chem Eur J. 2020.09; 26 (54): 12333-12337. ( PubMed , DOI )

  34. Yongwei Zhang, Kwangwoo Nam, Tsuyoshi Kimura, Pingli Wu, Naoko Nakamura, Yoshihide Hashimoto, Seiichi Funamoto, Akio Kishida: Preparation of gradient-type biological tissue–polymer complex for interlinking device Mater. Sci. Eng. C-Mater. Biol. Appl. 2020.09; 114 111017. ( DOI )

  35. Takahisa Watabe, Sho Kanzaki, Noriko Sato, Tatsuo Matsunaga, Masaaki Muramatsu, Kaoru Ogawa: Single nucleotide polymorphisms in tinnitus patients exhibiting severe distress. Sci Rep. 2020.08; 10 (1): 13023. ( PubMed , DOI )

  36. Takanobu Shimizu, Takeshi Nakamura, Hironori Inaba, Hiroaki Iwasa, Junichi Maruyama, Kyoko Arimoto-Matsuzaki, Takao Nakata, Hiroshi Nishina, Yutaka Hata: The RAS-interacting chaperone UNC119 drives the RASSF6-MDM2-p53 axis and antagonizes RAS-mediated malignant transformation. J. Biol. Chem.. 2020.08; 295 (32): 11214-11230. ( PubMed , DOI )

  37. Sumida Y, Harada R, Sumida T, Johmoto K, Uekusa H, Hosoya T: Synthesis of Dibenzofurans by Cu-Catalyzed Deborylative Ring Contraction of Dibenzoxaborins. Org Lett. 2020.08; 22 (16): 6687-6691. ( PubMed , DOI )

  38. Adachi K, Meguro T, Sakata Y, Igawa K, Tomooka K, Hosoya T, Yoshida S: Selective strain-promoted azide-alkyne cycloadditions through transient protection of bicyclo[6.1.0]nonynes with silver or gold. Chem Commun (Camb). 2020.08; 56 (68): 9823-9826. ( PubMed , DOI )

  39. Ikura Teikichi, Ito Nobutoshi: Pin1の変異体C113AとC113Sの構造解析(Structural analysis of Pin1 mutants C113A And C113S) 生物物理. 2020.08; 60 (Suppl.1-2): S144. ( 医中誌 )

  40. Takahiro Arakawa, Takahiro Arakawa Department of Biomedical Devices and Instrumentation, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10, Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan *(T.A.) Phone: +81-3-5280-8093. Fax: +81-3-5280-8094. Email: arakawa.bdi@tmd.ac.jp More by Takahiro Arakawa , Keisuke Tomoto, Hiroki Nitta, Koji Toma, Shuhei Takeuchi, Toshiaki Sekita, Shunsuke Minakuchi, Kohji Mitsubayashi: A Wearable Cellulose Acetate-Coated Mouthguard Biosensor for In Vivo Salivary Glucose Measurement Analytical Chemistry. 2020.08; 92 (18): 12201-12207.

  41. Nishio M, To Y, Maehama T, Aono Y, Otani J, Hikasa H, Kitagawa A, Mimori K, Sasaki T, Nishina H, Toyokuni S, Lydon JP, Nakao K, Wah Mak T, Kiyono T, Katabuchi H, Tashiro H, Suzuki A: Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice. Cancer science. 2020.07; 111 (10): 3576-3587. ( PubMed , DOI )

  42. Chen Siyuan, Miyazaki Takuya, Itoh Michiko, Matsumoto Hiroko, Moro-oka Yuki, Tanaka Miyako, Miyahara Yuji, Suganami Takayoshi, Matsumoto Akira: Temperature-Stable Boronate Gel-Based Microneedle Technology for Self-Regulated Insulin Delivery ACS APPLIED POLYMER MATERIALS. 2020.07; 2 (7): 2781-2790. ( DOI )

  43. Koji Mizukoshi Takahiro Arakawa Kohji Mitsubayashi: Convenience biosensing approach of lactic acid in stratum corneum for skin care assessment Skin Research and Technology. 2020.07; 26 (4): 455-464.

  44. Junpeng Qi, Kohei Tsuji, David Hymel, Terrence R. Burke, Jr., Michael Hudecek, Christoph Rader, Haiyong Peng: Chemically Programmable and Switchable CAR-T Therapy Angew. Chem., Int. Ed. 2020.07; 59 (29): 12178-12185 . ( PubMed , DOI )

  45. Watanabe K, Terao N, Isao Kii, Nakagawa R, Niwa T, Hosoya T: Indolizines Enabling Rapid Uncaging of Alcohols and Carboxylic Acids by Red Light-Induced Photooxidation. Org Lett. 2020.07; 22 (14): 5434-5438. ( PubMed , DOI )

  46. Tamura Y, Minami Y, Nishiyama Y, Sakata Y, Karaki F, Hosoya T, Yoshida S: Synthesis of multisubstituted cycloalkenes through carbomagnesiation of strained cycloalkynes. Chem Commun (Camb). 2020.07; 56 (52): 7147-7150. ( PubMed , DOI )

  47. Kobayashi A, Matsuzawa T, Hosoya T, Yoshida S: One-pot Synthesis of Allyl Sulfides from Sulfinate Esters and Allylsilanes through Reduction of Alkoxysulfonium Intermediates. Chem Lett. 2020.07; 49 (7): 813-816. ( DOI )

  48. Kobayashi T, Hosoya T, Yoshida S: Aryne Reaction and Cross-Coupling Approach for the Synthesis of Diverse #IN#IR-Arylphenylalanine Derivatives. Chem Lett. 2020.07; 49 (7): 809-812. ( DOI )

  49. Yasuda,K., Nakashima,A., Murata,A., Suzuki,K., Adachi,T: Euglena gracilis and β-glucan paramylon induce Ca2+ signaling in intestinal tract epithelial, immune, and neural cells. Nutrients. 2020.07; 12 (8): 2293. ( PubMed , DOI )

  50. Inouye S, Nakamura M, Taguchi J, Hosoya T: Identification of a novel oxidation product from yellow fluorophore in the complex of apoPholasin and dehydrocoelenterazine. Bioorganic & medicinal chemistry letters. 2020.07; 30 (19): 127435. ( PubMed , DOI )

  51. Matsumoto Akira, Kuwata Hirohito, Kimura Shinichiro, Matsumoto Hiroko, Ochi Kozue, Moro-oka Yuki, Watanabe Akiko, Yamada Hironori, Ishii Hitoshi, Miyazawa Taiki, Chen Siyuan, Baba Toshiaki, Yoshida Hiroshi, Nakamura Taichi, Inoue Hiroshi, Ogawa Yoshihiro, Tanaka Miyako, Miyahara Yuji, Suganami Takayoshi: Hollow fiber-combined glucose-responsive gel technology as an in vivo electronics-free insulin delivery system COMMUNICATIONS BIOLOGY. 2020.06; 3 (1): 313. ( PubMed , DOI )

  52. A long noncoding RNA regulates inflammation resolution by mouse macrophages through fatty acid oxidation activation. 2020.06; 117 (25): 14365-14375. ( PubMed , DOI )

  53. Kohei Tsuji, Kofi Baffour-Awuah Owusu, Takuya Kobayakawa, Rongyi Wang, Masayuki Fujino, Moemi Kaneko, Naoki Yamamoto, Tsutomu Murakami, Hirokazu Tamamura: Exploratory studies on CA-15L, an anti-HIV active HIV-1 capsid fragment. Bioorg. Med. Chem. 2020.06; 28 (11): 115488. ( PubMed , DOI )

  54. Nakaoka T, Uetake Y, Kaneko K, Niwa T, Ochia Hi, Irie S, Suezaki Y, Otsuka N, Hayashinaka E, Wada Y, Cui Y, Maeda K, Kusuhara H, Sugiyama Y, Hosoya T, Watanabe Y: Practical synthesis of [#U18#URF]Pitavastatin and Evaluation of Hepatobiliary Transport Activity in Rats by Positron Emission Tomography. Mol Pharm. 2020.06; 17 (6): 1884-1898. ( PubMed , DOI )

  55. Takahiro Arakawa, Takashi Aota, Kenta Iitani, Koji Toma, Iwasaki Y, Kohji Mitsubayash: Skin ethanol gas measurement system with a biochemical gas sensor and gas concentrator toward monitoring of blood volatile compounds Talanta. 2020.05; 115 887-895. ( DOI )

  56. Takuya Kobayakawa, Hikaru Takano, Takahiro Ishii, Kohei Tsuji, Nami Ohashi, Wataru Nomura, Toshiaki Furuta, Hirokazu Tamamura: Synthesis of hydrophilic caged DAG-lactones for chemical biology applications. Org. Biomol. Chem. 2020.05; 18 (22): 4217-4223 . ( PubMed , DOI )

  57. Sato Y, Nakamura K, Sumida Y, Hashizume D, Hosoya T, Ohmiya H: Generation of Alkyl Radical through Direct Excitation of Boracene-Based Alkylborate. J Am Chem Soc. 2020.05; 142 (22): 9938-9943. ( PubMed , DOI )

  58. Nishiyama Y, Hosoya T, Yoshida S: Synthesis of benzyl sulfides via substitution reaction at the sulfur of phosphinic acid thioesters. Chem Commun (Camb). 2020.05; 56 (43): 5771-5774. ( PubMed , DOI )

  59. Kobayashi A, Matsuzawa T, Hosoya T, Yoshida S: Sulfoxide synthesis from sulfinate esters under Pummerer-like conditions. Chem Commun (Camb). 2020.05; 56 (40): 5429-5432. ( PubMed , DOI )

  60. Mutsuura K, Sakata Y, Uchida K, Hosoya T, Yoshida S: Synthesis of Thioxanthones through Formal C–H Thiolation of Benzoic Acid Esters and Acid-mediated Direct Cyclization. Chem Lett. 2020.05; 49 (7): 753-756. ( DOI )

  61. Kim Y, Kanemoto K, Shimomori K, Hosoya T, Yoshida S: Functionalization of a Single C-F Bond of Trifluoromethylarenes Assisted by an #Iortho#IR-Silyl Group Using a Trityl-Based All-in-One Reagent with Ytterbium Triflate Catalyst. Chem Eur J. 2020.05; 26 (28): 6136-6140. ( PubMed , DOI )

  62. Inouye S, Miura-Sahara Y, Iimori R, Sakata Y, Hazama Y, Yoshida S, Nakamura M, Hosoya T: A novel yellow fluorescent protein of recombinant apoPholasin with dehydrocoelenterazine. Biochem Biophys Res Commun. 2020.05; 526 (2): 404-409. ( PubMed , DOI )

  63. Kanemoto K, Sakata Y, Hosoya T, Yoshida S: Synthesis of Phenoxathiins and Phenothiazines by Aryne Reactions with Thiosulfonates. Chem Lett. 2020.05; 49 (5): 593-596. ( DOI )

  64. Khamhanglit Chattarika, Tabata Miyuki, Goda Tatsuro, Matsumoto Akira, Miyahara Yuji, Sriyudthsak Mana: Protein immobilization method on the ion-sensitive FET(和訳中) 生体医歯工学共同研究拠点成果報告書. 2020.04; 令和元年度 162. ( 医中誌 )

  65. Signaling Pathways Potentially Responsible for Foam Cell Formation: Cholesterol Accumulation or Inflammatory Response-What is First? 2020.04; 21 (8): 2716. ( PubMed , DOI )

  66. Nishimura Yuya, Fukuda Yota, Okonogi Toya, Yoshikawa Soichiro, Karasuyama Hajime, Osakabe Naomi, Ikegaya Yuji, Sasaki Takuya, Adachi Takahiro: Dual real-time in vivo monitoring system of the brain-gut axis BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2020.04; 524 (2): 340-345. ( PubMed , DOI )

  67. Iitani K, Naisierding M, Toma K, Arakawa T, Mitsubayashi K: Evaluation for regional difference of skin-gas ethanol and sweat rate using alcohol dehydrogenase-mediated fluorometric gas-imaging system (sniff-cam). The Analyst. 2020.04; 145 (8): 2915-2924. ( PubMed , DOI )

  68. Meguro T, Sakata Y, Morita T, Hosoya T, Yoshida S: Facile assembly of three cycloalkyne-modules onto a platform compound bearing thiophene #IS#IR,#IS#IR-dioxide moiety and two azido groups. Chem Commun (Camb). 2020.04; 56 (34): 4720-4723. ( PubMed , DOI )

  69. Isobe, J., Maeda, S., Obata, Y., Iizuka, K., Nakamura, Y., Fujimura, Y., Kimizuka, T., Hattori, K., Kim, Y-G., Morita, T., Kimura, I., Offermanns, S., Adachi, T., Nakao, A., Kiyono, H., Takahashi, D., Hase, K: Commensal-bacteria-derived butyrate promotes the T-cell-independent IgA response in the colon. International Immunology. 2020.04; 32 (4): 243-258. ( DOI )

  70. Hanzawa N, Hashimoto K, Yuan X, Kawahori K, Tsujimoto K, Hamaguchi M, Tanaka T, Nagaoka Y, Nishina H, Morita S, Hatada I, Yamada T, Ogawa Y: Targeted DNA demethylation of the Fgf21 promoter by CRISPR/dCas9-mediated epigenome editing. Scientific reports. 2020.03; 10 (1): 5181. ( PubMed , DOI )

  71. Ultrasound modulates fluorescence strength and ABCG2 mRNA response to aminolevulinic acid in glioma cells. 2020.03; 87 (6): 310-317. ( PubMed , DOI )

  72. Minn AKK, Sato N, Mieno MN, Arai T, Muramatsu M: Association study of long non-coding RNA HOTAIR rs920778 polymorphism with the risk of cancer in an elderly Japanese population. Gene. 2020.03; 729 144263. ( PubMed , DOI )

  73. Abudushataer M, Sato N, Mieno M, Sawabe M, Muramatsu M, Arai T: Association of CYP2A6 gene deletion with cancers in Japanese elderly: an autopsy study. BMC Cancer. 2020.03; 20 (1): 186. ( PubMed , DOI )

  74. Shiozaki Y, Sakurai S, Sakamoto R, Matsumoto A, Maruoka K: Iron-Catalyzed Radical Cleavage/C-C Bond Formation of Acetal-Derived Alkylsilyl Peroxides. Chemistry, an Asian journal. 2020.03; 15 (5): 573-576. ( PubMed , DOI )

  75. Erika Ishihara, Yuya Nagaoka, Toshiaki Okuno, Satoshi Kofuji, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Kenya Kamimura, Shuji Terai, Takehiko Yokomizo, Yukihiko Sugimoto, Yasuyuki Fujita, Akira Suzuki, Hiroshi Nishina: Prostaglandin E2 and its receptor EP2 trigger signaling that contributes to YAP-mediated cell competition. Genes Cells. 2020.03; 25 (3): 197-214. ( PubMed , DOI )

  76. Kenta Iitani, Munire Naisierding, Koji Toma, Takahiro Arakawa, Kohji Mitsubayashi: Evaluation for regional difference of skin-gas ethanol and sweat rate using alcohol dehydrogenase-mediated fluorometric gas-imaging system (sniff-cam) Analyst. 2020.03; 145 2915-2924.

  77. Yuya Hanazono, Kazuki Takeda, Kunio Miki: Characterization of perdeuterated high-potential iron-sulfur protein with high-resolution X-ray crystallography. Proteins. 2020.02; 88 (2): 251-259. ( PubMed , DOI )

  78. Kenya Kamimura, Takeshi Yokoo, Hiroyuki Abe, Norihiro Sakai, Takuro Nagoya, Yuji Kobayashi, Masato Ohtsuka, Hiromi Miura, Akira Sakamaki, Hiroteru Kamimura, Norio Miyamura, Hiroshi Nishina, Shuji Terai: Effect of Diphtheria Toxin-Based Gene Therapy for Hepatocellular Carcinoma. Cancers (Basel). 2020.02; 12 (2): ( PubMed , DOI )

  79. Inouye S, Sahara-Miura Y, Nakamura M, Hosoya T: Expression, purification, and characterization of recombinant apoPholasin. Protein Expr Purif. 2020.02; 171 105615. ( PubMed , DOI )

  80. Kobayashi T, Hosoya T, Yoshida S: Consecutive Aryne Generation Strategy for the Synthesis of 1,3-Diarylpyrazoles. J Org Chem. 2020.02; 85 (6): 4448-4462. ( PubMed , DOI )

  81. Niwa T, Hosoya T: Molecular Renovation Strategy for Expeditious Synthesis of Molecular Probes. Bull Chem Soc Jpn. 2020.02; 93 (2): 230-248. ( DOI )

  82. Iitani K, Toma K, Arakawa T, Mitsubayashi K: Transcutaneous Blood VOC Imaging System (Skin-Gas Cam) with Real-Time Bio-Fluorometric Device on Rounded Skin Surface. ACS sensors. 2020.02; 5 (2): 338-345. ( PubMed , DOI )

  83. Role of Phagocytosis in the Pro-Inflammatory Response in LDL-Induced Foam Cell Formation; a Transcriptome Analysis. 2020.01; 21 (3): 817. ( PubMed , DOI )

  84. Masaki Watanabe, Yoshihide Hashimoto, Tsuyoshi Kimura, Akio Kishida: Characterization of engineering plastics plasticized using supercritical CO2 Polymers. 2020.01; 12 (1): 134. ( DOI )

  85. Daisuke Matsumoto, Hirokazu Tamamura, Wataru Nomura: TALEN-Based Chemically Inducible, Dimerization-Dependent, Sequence-Specific Nucleases Biochemistry . 2020.01; 59 (2): 197-204. ( PubMed , DOI )

  86. Yazaki J, Kawashima Y, Ogawa T, Kobayashi A, Okoshi M, Watanabe T, Yoshida S, Kii I, Egami S, Amagai M, Hosoya T, Shiroguch Ki, Ohara O: HaloTag-based conjugation of proteins to barcoding-oligonucleotides. Nucleic Acids Res. 2020.01; 48 (2): e8. ( PubMed , DOI )

  87. Aihara, Y., Fukuda, Y., Takizawa, A., Osakabe, N., Aida, T., Tanaka, K., Yoshikawa, S., Karasuyama, H., Adachi, T: Visualization of mechanical stress-mediated Ca(2+) signaling in the gut using intravital imaging. Bioscience of Microbiota, Food and Health. 2020; 39 (4): 209-18.

  88. Aihara Yoshiko, Fukuda Yota, Takizawa Akiyoshi, Osakabe Naomi, Aida Tomomi, Tanaka Kohichi, Yoshikawa Soichiro, Karasuyama Hajime, Adachi Takahiro: Visualization of mechanical stress-mediated Ca2+ signaling in the gut using intravital imaging BIOSCIENCE OF MICROBIOTA FOOD AND HEALTH. 2020; 39 (4): 209-218. ( PubMed , DOI )

  89. Kumazawa T, Kotake K, Nishimura A, Asai N, Ugajin T, Yokozeki H, Adachi T: Isolation of food-derived bacteria inducing interleukin-22 in B cells. Bioscience of microbiota, food and health. 2020; 39 (1): 1-9. ( PubMed , DOI )

  90. Organ System Crosstalk in Cardiometabolic Disease in the Age of Multimorbidity. 2020; 7 64. ( PubMed , DOI )

  91. Manami Kodaka, Fengju Mao, Kyoko Arimoto-Matsuzaki, Masami Kitamura, Xiaoyin Xu, Zeyu Yang, Kentaro Nakagawa, Junichi Maruyama, Kana Ishii, Chihiro Akazawa, Takuya Oyaizu, Naoki Yamamoto, Mari Ishigami-Yuasa, Nozomi Tsuemoto, Shigeru Ito, Hiroyuki Kagechika, Hiroshi Nishina, Yutaka Hata: Characterization of a novel compound that promotes myogenesis via Akt and transcriptional co-activator with PDZ-binding motif (TAZ) in mouse C2C12 cells. PLoS ONE. 2020; 15 (4): e0231265. ( PubMed , DOI )

  92. Hirofumi Omori, Miki Nishio, Muneyuki Masuda, Yosuke Miyachi, Fumihito Ueda, Takafumi Nakano, Kuniaki Sato, Koshi Mimori, Kenichi Taguchi, Hiroki Hikasa, Hiroshi Nishina, Hironori Tashiro, Tohru Kiyono, Tak Wah Mak, Kazuwa Nakao, Takashi Nakagawa, Tomohiko Maehama, Akira Suzuki: YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma. Sci Adv. 2020; 6 (12): eaay3324. ( PubMed , DOI )

  1. Ryo Goto, Kenya Kamimura, Yoko Shinagawa-Kobayashi, Norihiro Sakai, Takuro Nagoya, Yusuke Niwa, Masayoshi Ko, Kohei Ogawa, Ryosuke Inoue, Takeshi Yokoo, Akira Sakamaki, Hiroteru Kamimura, Satoshi Abe, Hiroshi Nishina, Shuji Terai: Inhibition of sodium glucose cotransporter 2 (SGLT2) delays liver fibrosis in a medaka model of nonalcoholic steatohepatitis (NASH). FEBS Open Bio. 2019.12; 9 (4): 643-652. ( PubMed , DOI )

  2. Takuro Nagoya, Kenya Kamimura, Ryo Goto, Yoko Shinagawa-Kobayashi, Yusuke Niwa, Atsushi Kimura, Norihiro Sakai, Masayoshi Ko, Hiroshi Nishina, Shuji Terai: Inhibition of sodium-glucose cotransporter 2 ameliorates renal injury in a novel medaka model of nonalcoholic steatohepatitis-related kidney disease. FEBS Open Bio. 2019.12; 9 (12): 2016-2024. ( PubMed , DOI )

  3. Yang Tai, Kiyofumi Takaba, Yuya Hanazono, Hoang Anh Dao, Kunio Miki, Kazuki Takeda: X-ray crystallographic studies on the hydrogen isotope effects of green fluorescent protein at sub-ångström resolutions. Acta Crystallogr D Struct Biol. 2019.12; 75 (12): 1096-1106. ( PubMed , DOI )

  4. Jun Negishi, Seiichi Funamoto, Yoshihide Hashimoto, Kotaro Yanagisawa: PLA-collagen composite scaffold fabrication by vacuum pressure impregnation Tissue Eng Part C: Methods. 2019.12; 25 (12): 742-747. ( DOI )

  5. Hatano H, Goda T, Matsumoto A, Miyahara Y: Induced Proton Dynamics on Semiconductor Surfaces for Sensing Tight Junction Formation Enhanced by an Extracellular Matrix and Drug. ACS sensors. 2019.12; ( PubMed , DOI )

  6. Nakamura Y, Yoshida S, Hosoya T: Recent Advances in Synthetic Hetaryne Chemistry. Heterocycles. 2019.12; 98 (12): 1623-1677. ( DOI )

  7. Kitakaze K, Taniuchi S, Kawano E, Hamada Y, Miyake M, Oyadomari M, Kojima H, Kosako H, Kuribara T, Yoshida S, Hosoya T, Oyadomari S: Cell-based HTS identifies a chemical chaperone for preventing ER protein aggregation and proteotoxicity. eLife. 2019.12; 8 e43302. ( PubMed , DOI )

  8. Maeda Kenji, Matsuda Kouki, Islam Saiful, Kobayakawa Takuya, Tsuchiya Kiyoto, Hattori Shin-ichiro, Gatanaga Hiroyuki, Oka Shinichi, Yoshimura Kazuhisa, Tamamura Hirokazu, Mitsuya Hiroaki, Satou Yorifumi: HIV持続潜伏感染に関する最先端研究(Treatment of HIV-1-reservoirs using latency-reversing agents(LRAs) toward HIV cure) 日本エイズ学会誌. 2019.11; 21 (4): 314. ( 医中誌 )

  9. Matsumoto A, Numata K: Biomaterials Science and Engineering in Japan: Attractive, Multidisciplinary, and Essential Research Field in Japan. ACS biomaterials science & engineering. 2019.11; 5 (11): 5559-5560. ( PubMed , DOI )

  10. Chen Siyuan, Matsumoto Hiroko, Moro-oka Yuki, Tanaka Miyako, Miyahara Yuji, Suganami Takayoshi, Matsumoto Akira: Smart Microneedle Fabricated with Silk Fibroin Combined Semi interpenetrating Network Hydrogel for Glucose-Responsive Insulin Delivery ACS BIOMATERIALS SCIENCE & ENGINEERING. 2019.11; 5 (11): 5781-5789. ( DOI )

  11. Uchida K, Minami Y, Yoshida S, Hosoya T: Synthesis of Diverse γ-Aryl-β-ketoesters via Aryne Intermediates Generated by C-C Bond Cleavage. Org Lett. 2019.11; 21 (22): 9019-9023. ( PubMed , DOI )

  12. Nakamura Y, Ozawa S, Yoshida S, Hosoya T: Facile Synthesis of Diverse 2,6-Disubstituted Arylsilanes via Silylamination and Silylsulfanylation of Aryne Intermediates Generated from #Io#IR-Iodoaryl Triflates. Chem Lett. 2019.11; 48 (11): 1296-1299. ( DOI )

  13. Sato N, Miyasaka N: Stratified analysis of the correlation between gestational weight gain and birth weight for gestational age: a retrospective single-center cohort study in Japan. BMC Pregnancy and Childbirth. 2019.11; 19 (1): 402. ( PubMed , DOI )

  14. Nishiguchi A, Numoto N, Ito N, Azuma T, Oda M: Three-dimensional structure of a high affinity anti-(4-hydroxy-3-nitrophenyl)acetyl antibody possessing a glycine residue at position 95 of the heavy chain. Molecular immunology. 2019.10; 114 545-552. ( PubMed , DOI )

  15. Toma Koji, Oishi Koki, Kato Misato, Kurata Kanako, Yoshimura Naoyuki, Arakawa Takahiro, Yatsuda Hiromi, Kanamori Kiyoko, Mitsubayashi Kohji: Precipitate-enhanced SAW immunosensor for sensitive monitoring of mite allergens SENSORS AND ACTUATORS B-CHEMICAL. 2019.10; 296 ( DOI )

  16. Toma Koji, Oishi Koki, Yoshimura Naoyuki, Arakawa Takahiro, Yatsuda Hiromi, Mitsubayashi Kohji: Repeated immunosensing by a dithiobis(succinimidyl propionate)-modified SAW device TALANTA. 2019.10; 203 274-279. ( DOI )

  17. Yoshikawa S, Oh-hora M, Hashimoto R, Miyake K, Adachi T, Kawano Y, Yamanishi Y, Kamiya A, Karasuyama H: Pivotal role of STIM2, but not STIM1, in IL-4 production by IL-3-stimulated basophils EUROPEAN JOURNAL OF IMMUNOLOGY. 2019.10; 49 584-585.

  18. Yoshikawa S., Oh-hora M., Hashimoto R., Miyake K., Adachi T., Kawano Y., Yamanishi Y., Kamiya A., Karasuyama H.: Pivotal role of STIM2, but not STIM1, in IL-4 production by IL-3-stimulated basophils EUROPEAN JOURNAL OF IMMUNOLOGY. 2019.10; 49 584-585.

  19. Mohammad Mamun Alam, Takeo Kuwata, Kazuki Tanaka, Muntasir Alam, Shokichi Takahama, Kazuya Shimura, Masao Matsuoka, Natsuki Fukuda, Hiroshi Morioka, Hirokazu Tamamura, Shuzo Matsushita: Synergistic Inhibition of Cell-to-cell HIV-1 Infection by Combinations of Single Chain Variable Fragments and Fusion Inhibitors Biochem Biophys Rep.. 2019.09; 20 100687.

  20. Yoshihide Hashimoto, Seiichi Funamoto, Shuji Sasaki, Jun Negishi, Shinya Hattori, Takako Honda, Tsuyoshi Kimura, Hisatoshi Kobayashi, Akio Kishida: Re-epithelialization and remodeling of decellularized corneal matrix in a rabbit corneal epithelial wound model Mater Sci Eng C-Mater Biol App. 2019.09; 102 238-246. ( DOI )

  21. Yoshida S, Goto S, Nishiyama Y, Hazama Y, Kondo M, Matsushita T, Hosoya T: Effect of Resonance on the Clickability of Alkenyl Azides in the Strain-promoted Cycloaddition with Dibenzo-fused Cyclooctynes. Chem Lett. 2019.09; 48 (9): 1038-1041. ( DOI )

  22. Taiki Miyazawa, Akira Matsumoto, Yuji Miyahara: Determination of Intra- and Extra-cellular Vitamin C Dynamics GIT Laboratory Journal. 2019.09;

  23. Masuno Hiroyuki, Kazui Yuko, Tanatani Aya, Fujii Shinya, Kawachi Emiko, Ikura Teikichi, Ito Nobutoshi, Yamamoto Keiko, Kagechika Hiroyuki: Development of novel lithocholic acid derivatives as vitamin D receptor agonists BIOORGANIC & MEDICINAL CHEMISTRY. 2019.08; 27 (16): 3674-3681. ( PubMed , DOI )

  24. Kenta Iitani, Koji Toma, Takahiro Arakawa, Kohji Mitsubayashi: Ultrasensitive sniff-cam for biofluorometric-imaging of breath ethanol caused by metabolism of intestinal flora Analytical Chemistry. 2019.08; 91 (15): 9458-9465. ( PubMed , DOI )

  25. Marjan Majdinasab, Kohji Mitsubayashi, Jean Louis Marty: Optical and Electrochemical Sensors and Biosensors for the Detection of Quinolones Trends in Biotechnology. 2019.08; 37 898-915. ( DOI )

  26. Numoto Nobutaka, Fukumori Yoshihiro, Miki Kunio, Ito Nobutoshi: 巨大ヘモグロビンのアロステリック中間体の時分割構造解析(Time-resolved structure analysis of allosteric intermediate of the giant hemoglobin) 生物物理. 2019.08; 59 (Suppl.1-2): S245. ( 医中誌 )

  27. Yasukochi Shotaro, Numoto Nobutaka, Hori Kiminori, Tenno Natsuko, Tenno Takeshi, Ito Nobutoshi, Hiroaki Hidekazu: ヒトDishevelled1 PDZドメインと阻害剤の共結晶構造解析(Crystal structure of human Dishevelled1 PDZ with its inhibitor) 生物物理. 2019.08; 59 (Suppl.1-2): S240. ( 医中誌 )

  28. M. Funasaki, C. Minato, M. Nonaka, M. Ozawa, A. Kishida, A. Ohsaki: New friedelane triterpenes from Anchietea Pyrifolia Phytochem Lett. 2019.08; 32 42-46. ( DOI )

  29. Sato N, Miyasaka N: Heterogeneity in fetal growth velocity. Scientific reports. 2019.08; 9 (1): 11304. ( PubMed , DOI )

  30. Takuya Kobayakawa, Kento Ebihara, Yuzuna Honda, Masayuki Fujino, Wataru Nomura, Naoki Yamamoto, Tsutomu Murakami, Hirokazu Tamamura: Dimeric C34 Derivatives Linked through Disulfide Bridges as New HIV-1 Fusion Inhibitors. Chembiochem. 2019.08; 20 (16): 2101-2108. ( PubMed , DOI )

  31. Fujii Yasuyuki, Suzuki Kenta, Adachi Takahiro, Taira Shu, Osakabe Naomi: Corticotropin-releasing hormone is significantly upregulated in the mouse paraventricular nucleus following a single oral dose of cinnamtannin A2 as an (-)-epicatechin tetramer JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION. 2019.07; 65 (1): 29-33. ( DOI )

  32. Siyuan Chen, Hiroko Matsumoto, Yuki Moro-oka, Miyako Tanaka, Yuji Miyahara, Takayoshi Suganami, Akira Matsumoto: Smart Microneedle Fabricated with Silk Fibroin Combined Semi-interpenetrating Network Hydrogel for Glucose-Responsive Insulin Delivery ACS Biomaterials Science & Enginering. 2019.07;

  33. Siyuan Chen, Hiroko Matsumoto, Yuki Moro-oka, Miyako Tanaka, Yuji Miyahara, Takayoshi Suganami, Akira Matsumoto: Smart Microneedle Fabricated with Silk Fibroin Combined Semi-interpenetrating Network Hydrogel for Glucose-Responsive Insulin Delivery ACS Biomaterials Science & Enginering. 2019.07;

  34. N. Nakamura, A. Ito, T. Kimura, A. Kishida: Extracellular matrix induces periodontal ligament reconstruction in vivo Int J Mol Sci. 2019.07; 20 (13): 3277. ( DOI )

  35. Uetake Y, Isoda M, Niwa T, Hosoya T: Synthesis of (2,2-Diborylvinyl)arenes by Rhodium-Catalyzed Desulfanylative #Igem#IR-Diborylation of 2-Arylvinyl Sulfides. Org Lett. 2019.07; 21 (13): 4933-4938. ( PubMed , DOI )

  36. Nakamura Y, Miyata Y, Uchida K, Yoshida S, Hosoya T: 3-Thioaryne Intermediates for the Synthesis of Diverse Thioarenes. Org Lett. 2019.07; 21 (13): 5252-5258. ( PubMed , DOI )

  37. Yoshida S, Hazama Y, Kanemoto K, Nakamura Y, Hosoya T: Facile Synthesis of Diverse #Io#IR-Iodoaryl Triflates from #Io#IR-Silylaryl Triflates by Aluminum-mediated Desilyliodination. Chem Lett. 2019.07; 48 (7): 742-745. ( DOI )

  38. Kenji Maeda, Debananda Das, Takuya Kobayakawa, Hirokazu Tamamura, Hiroaki Takeuchi: Discovery and Development of anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication. Current topics in medicinal chemistry. 2019.07; 19 (18): 1621-1649. ( PubMed , DOI )

  39. Toda K, Mizutani K, Minami I, Ye M, Arakawa T, Mitsubayashi K, Ogawa Y, Araki K, Shinada K: Effects of oral health instructions on glycemic control and oral health status of periodontitis patients with type 2 diabetes mellitus: A preliminary observation. Journal of Dental Sciences. 2019.06; 14 (2): 171-177. ( PubMed , DOI )

  40. N. Watanabe, M. Mizuno, J. Matsuda, N. Nakamura, K. Otabe, H. Katano, N. Ozeki, Y. Kohno, T. Kimura, K. Tsuji, H. Koga, A. Kishida, I. Sekiya: Comparison of high‐hydrostatic‐pressure decellularized versus freeze‐thawed porcine menisci J Orthop Res. 2019.06; 37 (11): 2466-2475. ( DOI )

  41. Yoshida S, Hosoya T: Target Identification of Bioactive Compounds by Photoaffinity Labeling Using Diazido Probes. Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules – The Shape of Organic Synthesis to Come. 2019.06; 335-355. ( DOI )

  42. Miyazawa Taiki, Matsumoto Akira, Miyahara Yuji: Determination of cellular vitamin C dynamics by HPLC-DAD ANALYST. 2019.06; 144 (11): 3483-3487. ( PubMed , DOI )

  43. Goda T, Imaizumi Y, Hatano H, Matsumoto A, Ishihara K, Miyahara Y: Translocation Mechanisms of Cell-Penetrating Polymers Identified by Induced Proton Dynamics. Langmuir : the ACS journal of surfaces and colloids. 2019.06; 35 (24): 8167-8173. ( PubMed , DOI )

  44. Toda K, Mizutani K, Minami I, Ye M, Arakawa T, Mitsubayashi K, Ogawa Y, Araki K, Shinada K: Effects of oral health instructions on glycemic control and oral health status of periodontitis patients with type 2 diabetes mellitus: A preliminary observation Journal of Dental Sciences. 2019.06; 14 (2): 171-177. ( DOI )

  45. Meguro T, Chen S, Kanemoto K, Yoshida S, Hosoya T: Modular Synthesis of Unsymmetrical Doubly-ring-fused Benzene Derivatives Based on a Sequential Ring Construction Strategy Using Oxadiazinones as a Platform Molecule. Chem Lett. 2019.06; 48 (6): 582-585. ( DOI )

  46. Nishiyama Y, Misawa Y, Hazama Y, Oya K, Yoshida S, Hosoya T: Synthesis of Diverse 3-Azido-5-(azidomethyl)benzene Derivatives via Formal C–H Azidation and Functional Group-Selective Transformations. Heterocycles. 2019.06; 99 (2): 1053-1072. ( DOI )

  47. Watanabe K, Tsuda J, Ochiai H, Niwa T, Hosoya T: Divergent Synthesis of Photoaffinity Probe Candidates by Click Reactions of Azido-Substituted Aryltrifluoromethyldiazirines. Heterocycles. 2019.06; 99 (2): 1366-1387. ( DOI )

  48. Kiyofumi Takaba, Yang Tai, Haruhiko Eki, Hoang-Anh Dao, Yuya Hanazono, Kazuya Hasegawa, Kunio Miki, Kazuki Takeda: Subatomic resolution X-ray structures of green fluorescent protein. IUCrJ. 2019.05; 6 (3): 387-400. ( PubMed , DOI )

  49. Maxwell M Sakyiamah, Wataru Nomura, Takuya Kobayakawa, Hirokazu Tamamura: Development of a NanoBRET-Based Sensitive Screening Method for CXCR4 Ligands. Bioconjug. Chem.. 2019.05; 30 (5): 1442-1450. ( PubMed , DOI )

  50. Tay Zar Kyaw, Seiji Yamaguchi, Chihiro Imai, Marina Uematsu and Noriko Sato: The utility of post-test newborn blood spot screening cards for epigenetic association analyses: association between HIF3A methylation and birth weight for gestational age Journal of Human Genetics . 2019.05; ( DOI )

  51. Kenta Iitani, Yuuki Hayakawa, Koji Toma, Takahiro Arakawa, Kohji Mitsubayashi: Switchable sniff-cam (gas-imaging system) based on redox reactions of alcohol dehydrogenase for ethanol and acetaldehyde in exhaled breath. Talanta. 2019.05; 197 249-256. ( PubMed , DOI )

  52. P. Wu, N. Nakamura, H. Morita, K. Nam, T. Fujisato, T. Kimura, A. Kishida: A hybrid small‐diameter tube fabricated from decellularized aortic intima‐media and electrospun fiber for artificial small‐diameter blood vessel J Biomed Mater Res Part A. 2019.05; 107 (5): 1064-1070. ( DOI )

  53. Yoshikawa Soichiro, Oh-hora Masatsugu, Hashimoto Ryota, Nagao Toshihisa, Peters Louis, Egawa Mayumi, Ohta Takuya, Miyake Kensuke, Adachi Takahiro, Kawano Yohei, Yamanishi Yoshinori, Karasuyama Hajime: Pivotal role of STIM2, but not STIM1, in IL-4 production by IL-3-stimulated murine basophils SCIENCE SIGNALING. 2019.04; 12 (576): ( DOI )

  54. Khamhanglit Chattarika, Tabata Miyuki, Goda Tatsuro, Matsumoto Akira, Miyahara Yuji, Kul-eung Pornnapat, Sriyudthsak Mana, Nakajima Anri: ISFETゲート表面の機能化によるpH感度への影響(Effect of functionalization of ISFET gate surface on pH sensitivity) 生体医歯工学共同研究拠点成果報告書. 2019.04; 平成30年度 165. ( 医中誌 )

  55. Ratanaporncharoen Chindanai, Tabata Miyuki, Goda Tatsuro, Matsumoto Akira, Miyahara Yuji, Ishihara Noboru, Masu Kazuya, Sriyudthsak Mana: Dental caries evaluation using wireless pH sensor: Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Chindanai(和訳中) 生体医歯工学共同研究拠点成果報告書. 2019.04; 平成30年度 119. ( 医中誌 )

  56. Yoshizumi Toshihiro, Goda Tatsuro, Yatabe Rui, Oki Akio, Matsumoto Akira, Oka Hiroaki, Washio Takashi, Toko Kiyoshi, Miyahara Yuji: Field-effect transistor array modified by a stationary phase to generate informative signal patterns for machine learning-assisted recognition of gas-phase chemicals MOLECULAR SYSTEMS DESIGN & ENGINEERING. 2019.04; 4 (2): 386-389. ( DOI )

  57. T. Kimura, M. Kondo, Y. Hashimoto, T. Fujisato, N. Nakamura, A. Kishida: Surface topography of PDMS replica transferred from various decellularized aortic lumens affects cellular orientation ACS Biomater Sci Eng. 2019.04; 5 (11): 5721-5726. ( DOI )

  58. Kanemoto K, Yoshida S, Hosoya T: Synthesis of Alkynyl Sulfides by Copper-Catalyzed Thiolation of Terminal Alkynes Using Thiosulfonates. Org Lett. 2019.04; 21 (9): 3172-3177. ( PubMed , DOI )

  59. Nakayama S, Shimonaka S, Elahi M, Nishioka K, Oji Y, Matsumoto SE, Li Y, Yoshino H, Mogushi K, Hatano T, Sato T, Ikura T, Ito N, Motoi Y, Hattori N: Tau aggregation and seeding analyses of two novel MAPT variants found in patients with motor neuron disease and progressive parkinsonism. Neurobiology of aging. 2019.03; 84 240.e13-240.e22. ( PubMed , DOI )

  60. Takahiro Arakawa, Takuma Suzuki, Masato Tsujii, Kenta Iitani, Po-Jen Chien, Ming Ye, Koji Toma, Yasuhiko Iwasaki, Kohji Mitsubayashi: Real-time monitoring of skin ethanol gas by a high-sensitivity gas phase biosensor (bio-sniffer) for the non-invasive evaluation of volatile blood compounds. Biosensors and Bioelectronics. 2019.03; 129 245-253. ( PubMed , DOI )

  61. Yoshida S, Kuribara T, Ito H, Meguro T, Nishiyama Y, Karaki F, Hatakeyama Y, Koike Y, Kii I, Hosoya T: A facile preparation of functional cycloalkynes via an azide-to-cycloalkyne switching approach. Chem Commun. 2019.03; 55 (24): 3556-3559. ( PubMed , DOI )

  62. Takuya Kobayakawa, Kiju Konno, Nami Ohashi, Kohei Takahashi, Ami Masuda, Kazuhisa Yoshimura, Shigeyoshi Harada, Hirokazu Tamamura: Soluble-type small-molecule CD4 mimics as HIV entry inhibitors BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2019.03; 29 (5): 719-723. ( PubMed , DOI )

  63. Pavethynath S, Imai C, Jin X, Hichiwa N, Takimoto H, Okamitsu M, Tarui I, Aoyama T, Yago S, Fudono A, Muramatsu M, Miyasaka N, Sato N: Metabolic and Immunological Shifts during Mid-to-Late Gestation Influence Maternal Blood Methylation of CPT1A and SREBF1. International journal of molecular sciences. 2019.03; 20 (5): ( PubMed , DOI )

  64. Hatano H, Goda T, Matsumoto A, Miyahara Y: Induced Proton Perturbation for Sensitive and Selective Detection of Tight Junction Breakdown. Analytical chemistry. 2019.03; 91 (5): 3525-3532. ( PubMed , DOI )

  65. Maxwell M. Sakyiamah, Takuya Kobayakawa, Masayuki Fujino, Makoto Konno, Tetsuo Narumi, Tomohiro Tanaka, Wataru Nomura, Naoki Yamamoto, Tsutomu Murakami, Hirokazu Tamamura: Design, synthesis and biological evaluation of low molecular weight CXCR4 ligands BIOORGANIC & MEDICINAL CHEMISTRY. 2019.03; 27 (6): 1130-1138. ( PubMed , DOI )

  66. Shimizu M, Tanaka N: IL-8-induced O-GlcNAc modification via GLUT3 and GFAT regulates cancer stem cell-like properties in colon and lung cancer cells. Oncogene. 2019.02; 38 (9): 1520-1533. ( PubMed , DOI )

  67. Chen Siyuan, Matsumoto Hiroko, Moro-oka Yuki, Tanaka Miyako, Miyahara Yuji, Suganami Takayoshi, Matsumoto Akira: Microneedle-Array Patch Fabricated with Enzyme-Free Polymeric Components Capable of On-Demand Insulin Delivery ADVANCED FUNCTIONAL MATERIALS. 2019.02; 29 (7): ( DOI )

  68. Fudono Ayako, Sato Noriko, Miyasaka Naoyuki: Trimester specific difference in exosomal microRNA expression(和訳中) 日本産科婦人科学会雑誌. 2019.02; 71 (臨増): S-200. ( 医中誌 )

  69. Hirayama J, Alifu Y, Hamabe R, Yamaguchi S, Tomita J, Maruyama Y, Asaoka Y, Nakahama KI, Tamaru T, Takamatsu K, Takamatsu N, Hattori A, Nishina S, Azuma N, Kawahara A, Kume K, Nishina H: The clock components Period2, Cryptochrome1a, and Cryptochrome2a function in establishing light-dependent behavioral rhythms and/or total activity levels in zebrafish. Scientific reports. 2019.01; 9 (1): 196. ( PubMed , DOI )

  70. Koji Toma, Fumiya Seshima, Ayumi Maruyama, Takahiro Arakawa, Kazuyoshi Yano, Kohji Mitsubayashi: Improved performance Air bio-battery based on efficient oxygen supply with a gas/liquid highly-porous diaphragm cell. Biosensors and Bioelectronics. 2019.01; 124-125 253-259. ( PubMed , DOI )

  71. Toyoda Y, Morimoto K, Suno R, Horita S, Yamashita K Hirata K, Sekiguchi Y, Yasuda S, Shiroishi M, Shimizu T, Urushibata Y, Kajiwara Y, Inazumi T, Hotta Y, Asada H, Nakane T, Shiimura Y, Nakagita T, Tsuge K, Yoshida S, Kuribara T, Hosoya T, Sugimoto Y, Nomura N, Sato M, Hirokawa T, Kinoshita M, Murata T, Takayama K, Yamamoto M, Narumiya S, Iwata S, Kobayashi T: Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface. Nat Chem Biol. 2019.01; 15 (1): 18-26. ( PubMed , DOI )

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  82. Nagaishi Takashi, Watabe Taro, Hosoya Akinori, Nisha Jose, Kojima Yudai, Adachi Takahiro, Watanabe Mamoru: Verification of Intestinal Microflora-Mediated Mucosal Homeostasis by Immunoglobulin A DIGESTION. 2019; 99 (1): 109.

  1. Nishita M., Nishikaku I., Yoshida E., Kamizaki K., Shibuya H., Matsumoto K., Minami Y.: Roil promotes invasion of lung adenocarcinoma cells through small GTPase Rif-mediated filopodia formation MOLECULAR BIOLOGY OF THE CELL. 2018.12; 29 (26): 231.

  2. Koji Toma, Keisuke Tomoto, Kumi Yokota, Nao Yasuda, Tatsuya Ishikawa, Takahiro Arakawa, Kohji Mitsubayashi: Mouthguard Controller for Unconstrained Control of External Devices Sensors and Materials. 2018.12; 30 (12): 3053-3060.

  3. Kumazawa T, Nishimura A, Asai N, Adachi T: Isolation of immune-regulatory Tetragenococcus halophilus from miso. PLOS ONE. 2018.12; 13 (12): e0208821 . ( DOI )

  4. Yoshihide Hashimoto, Sada-atsu Mukai, Yoshihiro Sasaki, Kazunari Akiyoshi: Nanogel tectonics for tissue engineering: Protein delivery systems with nanogel chaperones Adv Healthc Mater. 2018.12; 7 (23): e1800729. ( DOI )

  5. Zhang Z, Niwa T, Watanabe Y, Hosoya T: Palladium(II)-mediated rapid #U11#URC-cyanation of (hetero)arylborons. Org Biomol Chem. 2018.11; 16 (41): 7711-7716. ( PubMed , DOI )

  6. Takahashi K, Hosoya T, Onoe K, Takashima T, Tanaka M, Ishii A, Nakatomi Y, Tazawa S, Takahashi K, Doi H, Wada Y, Watanabe Y: Association between aromatase in human brains and personality traits. Sci Rep. 2018.11; 8 (1): 16841. ( PubMed , DOI )

  7. Yoshida S, Tanaka J, Nishiyama Y, Hazama Y, Matsushita T, Hosoya T: Further enhancement of the clickability of doubly sterically-hindered aryl azides by #Ipara#IR-amino substitution. Chem Commun. 2018.11; 54 (96): 13499-13502. ( PubMed , DOI )

  8. Takuya Kobayakawa, Nami Ohashi, Yuki Hirota, Kohei Takahashi, Yuko Yamada, Tetsuo Narumi, Kazuhisa Yoshimura, Shuzo Matsushita, Shigeyoshi Harada, Hirokazu Tamamura: Flexibility of small molecular CD4 mimics as HIV entry inhibitors. Bioorg. Med. Chem.. 2018.11; 26 (21): 5664-5671. ( PubMed , DOI )

  9. Wataru Nomura, Daisuke Matsumoto, Taisuke Sugii, Takuya Kobayakawa, Hirokazu Tamamura: Efficient and Orthogonal Transcription Regulation by Chemically Inducible Artificial Transcription Factors. Biochemistry. 2018.11; 57 (45): 6452-6459. ( PubMed , DOI )

  10. Naito Mitsuru, Yoshinaga Naoto, Ishii Takehiko, Matsumoto Akira, Miyahara Yuji, Miyata Kanjiro, Kataoka Kazunori: Fabrication of Intracellular ATP-responsive Polyion Complex Micelles for Smart Nucleotide Therapeutics Delivery(和訳中) 日本バイオマテリアル学会大会予稿集. 2018.11; 40回 489. ( 医中誌 )

  11. Oishi Yumiko, Manabe Ichiro: 炎症、修復、再生におけるマクロファージ(Macrophages in inflammation, repair and regeneration) International Immunology. 2018.11; 30 (11): 511-528. ( 医中誌 )

  12. Macrophages in inflammation, repair and regeneration. 2018.10; 30 (11): 511-528. ( PubMed , DOI )

  13. Kohji Mitsubayashi: Cavitas Biosensors: Noninvasive Approaches to Blood Glucose Monitoring for Diabetes Mellitus Sensors and Materials. 2018.10; 30 (10): 2313-2320.

  14. Kohji Mitsubayashi: Cavitas Biosensors: Noninvasive Approaches to Blood Glucose Monitoring for Diabetes Mellitus Sensors and Materials. 2018.10; 30 (10): 2313-2320.

  15. Sumida Y, Harada R, Sumida T, Hashizume D, Hosoya T: Hydrosilyl Group-directed Iridium-catalyzed peri-Selective C–H Borylation of Ring-fused (Hetero)Arenes. Chem Lett. 2018.10; 47 (10): 1251-1254. ( DOI )

  16. Matsuzawa T, Yoshida S, Hosoya T: Recent advances in reactions between arynes and organosulfur compounds. Tetrahedron Lett. 2018.10; 59 (48): 4197-4208 . ( DOI )

  17. Jin K, Imada T, Nakamura S, Izuta Y, Oonishi E, Shibuya M, Sakaguchi H, Adachi T, Tsubota K: Intravital Two-photon Imaging of Ca 2+ signaling in Secretory Organs of Yellow Cameleon Transgenic Mice. Scientific reports. 2018.10; 8 (1): 15880. ( PubMed , DOI )

  18. Inouye S, Tomabechi Y, Hosoya T, Sekine S, Shirouzu M: Slow luminescence kinetics of semi-synthetic aequorin: expression, purification and structure determination of #Icf3#IR-aequorin. J Biochem. 2018.09; 164 (3): 247-255. ( PubMed , DOI )

  19. Nishiyama Y, Kamada S, Yoshida S, Hosoya T: Generation of Arynes by Selective Cleavage of a Carbon–Phosphorus Bond of #Io#IR-(Diarylphosphinyl)aryl Triflates Using a Grignard Reagent. Chem Lett. 2018.09; 47 (9): 1216-1219. ( DOI )

  20. Rocio Otero, Michiyasu Ishizawa, Nobutaka Numoto, Teikichi Ikura, Nobutoshi Ito, Hiroaki Tokiwa, Antonio Mouriño, Makoto Makishima, Sachiko Yamada: Synthesis, Tissue Selective Biological Activities, and X-ray Crystal Structural Analysis of Its Vitamin D Receptor Complex. J. Med. Chem.. 2018.08; 61 (15): 6658-6673. ( PubMed , DOI )

  21. Teikichi Ikura, Naoya Tochio, Ryosuke Kawasaki, Mizuki Matsuzaki, Akihiro Narita, Mahito Kikumoto, Naoko Utsunomiya-Tate, Shin-Ichi Tate, Nobutoshi Ito: The trans isomer of Tau peptide is prone to aggregate, and the WW domain of Pin1 drastically decreases its aggregation. FEBS Lett.. 2018.08; 592 (18): 3082-3091. ( PubMed , DOI )

  22. Nobutaka Numoto, Narutoshi Kamiya, Gert-Jan Bekker, Yuri Yamagami, Satomi Inaba, Kentaro Ishii, Susumu Uchiyama, Fusako Kawai, Nobutoshi Ito, Masayuki Oda: Structural Dynamics of the PET-Degrading Cutinase-like Enzyme from Saccharomonospora viridis AHK190 in Substrate-Bound States Elucidates the Ca2+-Driven Catalytic Cycle. Biochemistry. 2018.08; 57 (36): 5289-5300. ( PubMed , DOI )

  23. Yuya Hanazono, Kazuki Takeda, Kunio Miki: Co-translational folding of α-helical proteins: structural studies of intermediate-length variants of the λ repressor. FEBS Open Bio. 2018.08; 8 (8): 1312-1321. ( PubMed , DOI )

  24. Fujii Y, Suzuki K, Hasegawa Y, Nanba F, Toda T, Adachi T, Taira S, Osakabe N: Single oral administration of flavan 3-ols induces stress responses monitored with stress hormone elevations in the plasma and paraventricular nucleus. Neuroscience letters . 2018.08; 682 106-111. ( DOI )

  25. Yukichi Horiguchi, Tatsuro Goda, Akira Matsumoto, Hiroaki Takeuchi, Shoji Yamaoka, Yuji Miyahara: Gold Nanoparticles with Ligand/Zwitterion Hybrid Layer for Individual Counting of Influenza A H1N1 Subtype Using Resistive Pulse Sensing. Langmuir. 2018.08; 35 (5): 1798-1806. ( PubMed , DOI )

  26. Yuya Tabakawa, Takuya Ohta, Soichiro Yoshikawa, Elisabeth J Robinson, Kayoko Yamaji, Kenji Ishiwata, Yohei Kawano, Kensuke Miyake, Yoshinori Yamanishi, Hiroshi Ohtsu, Takahiro Adachi, Naohiro Watanabe, Hirotaka Kanuka, Hajime Karasuyama: Histamine Released From Skin-Infiltrating Basophils but Not Mast Cells Is Crucial for Acquired Tick Resistance in Mice. Front Immunol. 2018.07; 9 1540. ( PubMed , DOI )

  27. Meguro T, Terashima N, Ito H, Koike Y, Kii I, Yoshida S, Hosoya T: Staudinger reaction using 2,6-dichlorophenyl azide derivatives for robust aza-ylide formation applicable to bioconjugation in living cells. Chem Commun. 2018.07; 54 (57): 7904-7907. ( PubMed , DOI )

  28. Matsuzawa T, Uchida K, Yoshida S, Hosoya T: Synthesis of Diverse Phenothiazines by Direct Thioamination of Arynes with #IS#IR-(#Io#IR-Bromoaryl)-#IS#IR-methylsulfilimines and Subsequent Intramolecular Buchwald–Hartwig Amination. Chem Lett. 2018.07; 47 (7): 825-828. ( DOI )

  29. Lino AC, Dang VD, Lampropoulou V, Welle A, Joedicke J, Pohar J, Simon Q, Thalmensi J, Baures A, Flühler V, Sakwa I, Stervbo U, Ries S, Jouneau L, Boudinot P, Tsubata T, Adachi T, Hutloff A, Dörner T, Zimber-Strobl U, de Vos AF, Dahlke K, Loh G, Korniotis S, Goosmann C, Weill JC, Reynaud CA, Kaufmann SHE, Walter J, Fillatreau S: LAG-3 Inhibitory Receptor Expression Identifies Immunosuppressive Natural Regulatory Plasma Cells. Immunity. 2018.07; 49 (1): 120-133.e9. ( DOI )

  30. Kei Toyama, Wataru Nomura, Takuya Kobayakawa, Hirokazu Tamamura: Delivery of a Proapoptotic Peptide to EGFR-Positive Cancer Cells by a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR. Bioconjug. Chem.. 2018.06; 29 (6): 2050-2057. ( PubMed , DOI )

  31. Yoshida S, Kuribara T, Morita T, Matsuzawa T, Morimoto K, Kobayashi T, Hosoya T: Expanding the synthesizable multisubstituted benzo[#Ib#IR]thiophenes via 6,7-thienobenzynes generated from #Io#IR-silylaryl triflate-type precursors. RSC Adv. 2018.06; 8 (39): 21754-21758. ( DOI )

  32. Meguro T, Yoshida S, Igawa K, Tomooka K, Hosoya T: Transient Protection of Organic Azides from Click Reactions with Alkynes by Phosphazide Formation. Org Lett. 2018.06; 20 (13): 4126-4130. ( PubMed , DOI )

  33. Asami Kawasaki, Masayasu Okada, Atsushi Tamada, Shujiro Okuda, Motohiro Nozumi, Yasuyuki Ito, Daiki Kobayashi, Tokiwa Yamasaki, Ryo Yokoyama, Takeshi Shibata, Hiroshi Nishina, Yutaka Yoshida, Yukihiko Fujii, Kosei Takeuchi, Michihiro Igarashi: Growth Cone Phosphoproteomics Reveals that GAP-43 Phosphorylated by JNK Is a Marker of Axon Growth and Regeneration. iScience. 2018.06; 4 190-203. ( PubMed , DOI )

  34. Naoki Miyamoto, Miho Yoshimura, Yuji Okubo, Kayo Suzuki-Nagata, Takeshi Tsumuraya, Nobutoshi Ito, Ikuo Fujii: Structural basis of the broad substrate tolerance of the antibody 7B9-catalyzed hydrolysis of p-nitrobenzyl esters. Bioorg. Med. Chem.. 2018.05; 26 (8): 1412-1417. ( PubMed , DOI )

  35. カーン・タホミナタレク , カブラル・オラシオ , 松元 亮, 片岡 一則: DEVELOPMENT OF 5-BORONOPICOLINIC ACID-INSTALLED POLYMERIC MICELLES FOR TARGETING SIALYLATED EPITOPES ON CANCER CELLS 日本DDS学会学術集会プログラム予稿集. 2018.05; 34回 202. ( 医中誌 )

  36. Hai Wenfeng, Goda Tatsuro, Takeuchi Hiroaki, Yamaoka Shoji, Horiguchi Yukichi, Matsumoto Akira, Miyahara Yuji: Human influenza virus detection using sialyllactose-functionalized organic electrochemical transistors SENSORS AND ACTUATORS B-CHEMICAL. 2018.05; 260 635-641. ( DOI )

  37. Ratanaporncharoen Chindanai, Tabata Miyuki, Watanagool Natthapol, Goda Tatsuro, Matsumoto Akira, Sriyudthsak Mana, Miyahara Yuji: Characterization and Optimization of Thermally Grown Iridium Oxide and Its Application to pH Sensors SENSORS AND MATERIALS. 2018.05; 30 (5 SI): 1175-1185. ( DOI )

  38. Yoshizumi Toshihiro, Goda Tatsuro, Matsumoto Akira, Miyahara Yuji: Gas-sensitive Field-effect Transistor Incorporating Polymer Layer and Porous Metal Electrode in the Gate Structure SENSORS AND MATERIALS. 2018.05; 30 (5 1): 1001-1008. ( DOI )

  39. Naoko Matsubara, Akihiro Imamura, Tatsuya Yonemizu, Chizuru Akatsu, Hongrui Yang, Akiharu Ueki, Natsuki Watanabe, Hajjaj Abdu-Allah, Nobutaka Numoto, Hiromu Takematsu, Shinobu Kitazume, Thomas F Tedder, Jamey D Marth, Nobutoshi Ito, Hiromune Ando, Hideharu Ishida, Makoto Kiso, Takeshi Tsubata: CD22-Binding Synthetic Sialosides Regulate B Lymphocyte Proliferation Through CD22 Ligand-Dependent and Independent Pathways, and Enhance Antibody Production in Mice. Front Immunol. 2018.04; 9 820. ( PubMed , DOI )

  40. Yoshida S, Kanno K, Kii I, Misawa Y, Hagiwara M, Hosoya T: Convergent synthesis of trifunctional molecules by three sequential azido-type-selective cycloadditions. Chem Commun. 2018.04; 54 (30): 3705-3708. ( PubMed , DOI )

  41. Kii I, Hirahara-Owada S, Yamaguchi M, Niwa T, Koike Y, Sonamoto R, Ito H, Takahashi K, Yokoyama C, Hayashi T, Hosoya T, Watanabe Y: Quantification of receptor activation by oxytocin and vasopressin in endocytosis-coupled bioluminescence reduction assay using nanoKAZ. Anal Biochem. 2018.04; 549 174-183. ( PubMed , DOI )

  42. Ratanaporncharoen Chindanai, Tabata Miyuki, Goda Tatsuro, Matsumoto Akira, Miyahara Yuji, Ishihara Noboru, Masu Kazuya, Sriyudthsak Mana: Ir/IrOxワイヤレスpHセンサーを用いた齲食部位のpHマッピング 生体医歯工学共同研究拠点成果報告書. 2018.04; 平成29年度 171. ( 医中誌 )

  43. Kaori Taniguchi, Mariko Funasaki, Akio Kishida, Samir K. Sadhu, Firoj Ahmed, Masami Ishibashi, Ayumi Ohsaki: Two new coumarins and a new xanthone from the leaves of Rhizophora mucronata Bioorganic & Medicinal Chemistry Letters. 2018.04; 28 (6): 1063-1066. ( DOI )

  44. Yongwei Zhang, Takuya Iwata, Kwangwoo Nam, Tsuyoshi Kimura, Pingli Wu, Naoko Nakamura, Yoshihide Hashimoto, Akio Kishida: Water absorption by decellularized dermis Heliyon. 2018.04; 4 (4): 1-17. ( DOI )

  45. Erika Ishihara, Hiroshi Nishina: The Hippo-YAP Pathway Regulates 3D Organ Formation and Homeostasis. Cancers (Basel). 2018.04; 10 (4): ( PubMed , DOI )

  46. Ajiro M, Sakai H, Onogi H, Yamamoto M, Sumi E, Sawada T, Nomura T, Kabashima K, Hosoya T, Hagiwara M: CDK9 Inhibitor FIT-039 Suppresses Viral Oncogenes E6 and E7 and Has a Therapeutic Effect on HPV-Induced Neoplasia. Clin Cancer Res. 2018.04; ( PubMed , DOI )

  47. Takahiro Arakawa, Rui Xie, Fumiya Seshima, Koji Toma, Kohji Mitsubayashi: Air bio-battery with a gas/liquid porous diaphragm cell for medical and health care devices Biosensors and Bioelectronics. 2018.04; 103 171-175. ( PubMed , DOI )

  48. Yukichi, Horiguchi, Tatsuro, Goda, Yuji, Miyahara: Simple functionalization method for single conical pores with a polydopamine layer. Applied Physics Express. 2018.04; 11 (4): 047001. ( DOI )

  49. Chindanai Ratanaporncharoen, Miyuki Tabata, Yuichi Kitasako, Masaomi Ikeda, Tatsuro Goda, Akira Matsumoto, Junji Tagami, Yuji Miyahara: pH Mapping on Tooth Surfaces for Quantitative Caries Diagnosis Using Micro Ir/IrOx pH Sensor. Anal. Chem.. 2018.03; 90 (7): 4925-4931. ( PubMed , DOI )

  50. Y. Sawa, G. Matsumiya, K. Matsuda, E. Tatsumi, T. Abe, K. Fukunaga, S. Ichiba, A. Kishida, 他: Journal of Artificial Organs 2017:the year in review J. Artif Organs. 2018.03; 21 (1): 1-7.

  51. Sato A, Shibuya H.: Glycogen synthase kinase 3ß functions as a positive effector in the WNK signaling pathway. PLoS One. 2018.03; 13 e0193204.

  52. Taro Watabe, Takashi Nagaishi, Naoya Tsugawa, Yudai Kojima, Nisha Jose, Akinori Hosoya, Michio Onizawa, Yasuhiro Nemoto, Shigeru Oshima, Tetsuya Nakamura, Hajime Karasuyama, Takahiro Adachi, Mamoru Watanabe: B cell activation in the cecal patches during the development of an experimental colitis model. Biochem. Biophys. Res. Commun.. 2018.02; 496 (2): 367-373. ( PubMed , DOI )

  53. Junichi Maruyama, Kazutoshi Inami, Fumiyoshi Michishita, Xinliang Jiang, Hiroaki Iwasa, Kentaro Nakagawa, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Norio Miyamura, Jun Hirayama, Hiroshi Nishina, Daichi Nogawa, Kouhei Yamamoto, Yutaka Hata: Novel YAP1 Activator, Identified by Transcription-Based Functional Screen, Limits Multiple Myeloma Growth. Mol. Cancer Res.. 2018.02; 16 (2): 197-211. ( PubMed , DOI )

  54. Enrico Tenaglia, Yuki Imaizumi, Yuji Miyahara, Carlotta Guiducci: Isothermal Multiple Displacement Amplification of DNA Templates in Minimally Buffered Conditions using Phi29 Polymerase Chemical Communications. 2018.02; 17 (57): 2158-2161. ( DOI )

  55. Takuya Kobayakawa, Yudai Matsuzaki, Kentaro Hozumi, Wataru Nomura, Motoyoshi Nomizu, Hirokazu Tamamura: Synthesis of a Chloroalkene Dipeptide Isostere-Containing Peptidomimetic and Its Biological Application. ACS Medicinal Chemistry Letters. 2018.01; 9 (1): 6-10. ( PubMed , DOI )

  56. Sayuri Udagawa, Sayaka Katagiri, Shogo Maekawa, Yasuo Takeuchi, Rina Komazaki, Anri Ohtsu, Naoki Sasaki, Takahiko Shiba, Kazuki Watanabe, Kazuyuki Ishihara, Noriko Sato, Naoyuki Miyasaka, Yuichi Izumi: Effect of Porphyromonas gingivalis infection in the placenta and umbilical cord in pregnant mice with low birth weight. Acta Odontol. Scand.. 2018.01; 1-9. ( PubMed , DOI )

  57. Naito Mitsuru, Yoshinaga Naoto, Ishii Takehiko, Matsumoto Akira, Miyahara Yuji, Miyata Kanjiro, Kataoka Kazunori: Enhanced Intracellular Delivery of siRNA by Controlling ATP-Responsivity of Phenylboronic Acid-Functionalized Polyion Complex Micelles MACROMOLECULAR BIOSCIENCE. 2018.01; 18 (1 SI): 1700357. ( DOI )

  58. Kenta Iitani, Toshiyuki Sato, Munire Naisierding, Yuuki Hayakawa, Koji Toma, Takahiro Arakawa, Kohji Mitsubayashi: Fluorometric sniff-cam (gas-imaging system) utilizing alcohol dehydrogenase for imaging concentration distribution of acetaldehyde in breath and transdermal vapor after drinking Analytical Chemistry. 2018.01; 90 (4): 2678-2685. ( DOI )

  59. Kenta Iitani, Po-Jen Chien, Takuma Suzuki, Koji Toma, Takahiro Arakawa, Yasuhiko Iwasaki, Kohji Mitsubayashi: Fiber-optic bio-sniffer (biochemical gas sensor) using ADH reverse reaction for exhaled acetaldehyde ACS Sensors. 2018.01; 3 (2): 425-431. ( DOI )

  60. Kanemoto K, Yoshida S, Hosoya T: Modified Conditions for Copper-Catalyzed #Iipso#IR-Thiolation of Arylboronic Acid Esters with Thiosulfonates. Chem Lett. 2018.01; 47 (1): 85-88. ( DOI )

  61. Koji Toma, Keisuke Tomoto, Kumi Yokota, Nao Yasuda, Tatsuya Ishikawa, Takahiro Arakawa, and Kohji Mitsubayashi: Mouthguard controller for unconstrained controlling of external devices Sensors and Materials. 2018; 30 (12): 3053-3060. ( DOI )

  62. Oishi Y, Manabe I: Krüppel-Like Factors in Metabolic Homeostasis and Cardiometabolic Disease. Frontiers in cardiovascular medicine. 2018; 5 69. ( PubMed , DOI )

  63. In vitro and in silico studies of the molecular interactions of epigallocatechin-3-o-gallate (egcg) with proteins that explain the health benefits of green tea 2018; 23 (6): ( PubMed , DOI )

  64. Akira Matsumoto, Yuji Miyahara: 'Borono-lectin' based engineering as a versatile platform for biomedical applications. Sci Technol Adv Mater. 2018; 19 (1): 18-30. ( PubMed , DOI )

  65. Hiroki Goto, Miki Nishio, Yoko To, Tatsuya Oishi, Yosuke Miyachi, Tomohiko Maehama, Hiroshi Nishina, Haruhiko Akiyama, Tak Wah Mak, Yuma Makii, Taku Saito, Akihiro Yasoda, Noriyuki Tsumaki, Akira Suzuki: in mice results in chondrodysplasia due to YAP1/TAZ-TEAD-dependent repression of SOX9. Development. 2018; 145 (6): ( PubMed , DOI )

  66. Kei Toyama, Takuya Kobayakawa, Wataru Nomura, Hirokazu Tamamura: Inhibition of EGFR Activation by Bivalent Ligands Based on a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR. Chem. Pharm. Bull.. 2018; 66 (11): 1083-1089. ( PubMed , DOI )

  67. Nakagawa Y, Ishimura K, Oya S, Kamino M, Fujii Y, Nanba F, Toda T, Ishii T, Adachi T, Suhara Y, Osakabe N: Comparison of the sympathetic stimulatory abilities of B-type procyanidins based on induction of uncoupling protein-1 in brown adipose tissue (BAT) and increased plasma catecholamine (CA) in mice. PloS one. 2018; 13 (7): e0201203. ( PubMed , DOI )

  1. Takahiro Adachi, Yoshikawa Soichiro, Karasuyama Hajime: B cell development and function Intravital imaging of Ca2+ signals in lymphocytes of the Ca2+ biosensor YC3.60 transgenic mice(和訳中) 日本免疫学会総会・学術集会記録. 2017.12; 46 (Proceedings): 3-E.

  2. Koji Toma, Yume Harashima, Naoyuki Yoshimura, Takahiro Arakawa, Hiromi Yatsuda, Kiyoko Kanamori, Kohji Mitsubayashi: Semicontinuous measurement of mite allergen (Der f 2) using a surface acoustic wave immunosensor under moderate pH for long sensor lifetime Sensors and Materials. 2017.12; 29 (12): 1679-1687. ( DOI )

  3. Kusuhara H, Takashima T, Fujii H, Takashima T, Tanaka M, Ishii A, Tazawa S, Takahashi K, Takahashi K, Tokai H, Yano T, Kataoka M, Inano A, Yoshida S, Hosoya T, Sugiyama Y, Yamashita S, Hojo T, Watanabe Y: Comparison of pharmacokinetics of newly discovered aromatase inhibitors by a cassette microdosing approach in healthy Japanese subjects. Drug Metab Pharmacokinet. 2017.12; 32 (6): 293-300. ( PubMed , DOI )

  4. Tatsuyuki Matsudaira, Kojiro Mukai, Taishin Noguchi, Junya Hasegawa, Tomohisa Hatta, Shun-Ichiro Iemura, Tohru Natsume, Norio Miyamura, Hiroshi Nishina, Jun Nakayama, Kentaro Semba, Takuya Tomita, Shigeo Murata, Hiroyuki Arai, Tomohiko Taguchi: Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells. Nat Commun. 2017.11; 8 (1): 1246. ( PubMed , DOI )

  5. Matsumoto Akira, Tanaka Miyako, Matsumoto Hiroko, Ochi Kozue, Moro-oka Yuki, Kuwata Hirohito, Yamada Hironori, Shirakawa Ibuki, Miyazawa Taiki, Ishii Hitoshi, Kataoka Kazunori, Ogawa Yoshihiro, Miyahara Yuji, Suganami Takayoshi: Synthetic "smart gel" provides glucose-responsive insulin delivery in diabetic mice SCIENCE ADVANCES. 2017.11; 3 (11): eaaq0723. ( DOI )

  6. Chien Po-Jen, Suzuki Takuma, Tsujii Masato, Ye Ming, Minami Isao, Toda Kanako, Otsuka Hiromi, Toma Koji, Arakawa Takahiro, Araki Kouji, Iwasaki Yasuhiko, Shinada Kayoko, Ogawa Yoshihiro, Mitsubayashi Kohji: Biochemical Gas Sensors (Biosniffers) Using Forward and Reverse Reactions of Secondary Alcohol Dehydrogenase for Breath Isopropanol and Acetone as Potential Volatile Biomarkers of Diabetes Mellitus ANALYTICAL CHEMISTRY. 2017.11; 89 (22): 12261-12268. ( PubMed , DOI )

  7. Yoshida S, Shimizu K, Uchida K, Hazama Y, Igawa K, Tomooka K, Hosoya T: Construction of Condensed Polycyclic Aromatic Frameworks through Intramolecular Cycloaddition Reactions Involving Arynes Bearing an Internal Alkyne Moiety. Chem Eur J. 2017.11; 23 (61): 15332-15335. ( PubMed , DOI )

  8. K. Akazawa, K. Iwasaki, M. Nagata, N. Yokoyama, H. Ayame, K. Yamaki, Y. Tanaka, I. Honda, C. Morioka, T. Kimura, M. Komaki, A. Kishida, Y. Izumi, I. Morita: Cell transfer technology for tissue engineering Inflammation and Regeneration. 2017.10; 37 (21): 1-6. ( DOI )

  9. Kazuki Mochizuki, Chihiro Imai, Noriko Sato, Takeo Kubota: The roles of epigenetics in developmental programming/Developmental Origins of Health and Disease theory. OBM Genetics. 2017.10; 1 (4): ( DOI )

  10. Ming Ye, Takahiro Arakawa, Po-Jen Chien, Takuma Suzuki, Koji Toma, Kohji Mitsubayashi: Acetone biosensor based on fluorometry of reduced nicotinamide adenine dinucleotide consumption in reversible reaction by secondary alcohol dehydrogenase IEEE Sensors Journal. 2017.10; ( DOI )

  11. Koji Toma, Daisuke Miki, Naoyuki Yoshimura, Takahiro Arakawa, Hiromi Yatsuda, Kohji Mitsubayashi: A gold nanoparticle-assisted sensitive SAW (surface acoustic wave) immunosensor with a regeneratable surface for monitoring of dust mite allergens Sensors and Actuators B: Chemical. 2017.10; 249 685-690. ( DOI )

  12. Rina Komazaki, Sayaka Katagiri, Hirokazu Takahashi, Shogo Maekawa, Takahiko Shiba, Yasuo Takeuchi, Yoichiro Kitajima, Anri Ohtsu, Sayuri Udagawa, Naoki Sasaki, Kazuki Watanabe, Noriko Sato, Naoyuki Miyasaka, Yuichiro Eguchi, Keizo Anzai, Yuichi Izumi: Periodontal pathogenic bacteria, Aggregatibacter actinomycetemcomitans affect non-alcoholic fatty liver disease by altering gut microbiota and glucose metabolism. Sci Rep. 2017.10; 7 (1): 13950. ( PubMed , DOI )

  13. Miyashita Satoshi, Adachi Toma, Yamashita Mariko, Sota Takayuki, Hoshino Mikio: Dynamics of the cell division orientation of granule cell precursors during cerebellar development MECHANISMS OF DEVELOPMENT. 2017.10; 147 1-7. ( DOI )

  14. Matsuzawa T, Uchida K, Yoshida S, Hosoya T: Synthesis of Diverse #Io#IR-Arylthio-Substituted Diaryl Ethers by Direct Oxythiolation of Arynes with Diaryl Sulfoxides Involving Migratory #IO#IR-Arylation. Org Lett. 2017.10; 19 (20): 5521-5524. ( PubMed , DOI )

  15. Hatakeyama M, Sakamoto Y, Ogata K, Sumida Y, Sumida T, Hosoya T, Nakamura S: A study on an unusual S#DN#DR2 mechanism in the methylation of benzyne through nickel-complexation. Phys Chem Chem Phys. 2017.10; 19 (39): 26926-26933. ( PubMed , DOI )

  16. Niwa T, Ochiai H, Hosoya T: Facile Transformation of α,β-Unsaturated Carboxylic Acids to Alkenylboronic Esters via Rhodium-Catalyzed Decarbonylative Borylation of α,β-Unsaturated Thioesters. Chem Lett. 2017.09; 46 (9): 1315-1318. ( DOI )

  17. Midori Taniguchi, Hirokazu Saito, Kohji Mitsubayashi K: Repetitive Immunosensor with a Fiber-Optic Device and Antibody-Coated Magnetic Beads for Semi-Continuous Monitoring of Escherichia coli O157:H7 Sensors. 2017.09; 17 (9): 2145. ( DOI )

  18. Koji Toma, Mai Horibe, Chisato Kishikawa, Naoyuki Yoshimura, Takahiro Arakawa, Hiromi Yatsuda, Hiroji Shimomura, Kohji Mitsubayashi: Rapid and repetitive immunoassay with a surface acoustic wave device for monitoring of dust mite allergens Sensors and Actuators B: Chemical. 2017.09; 248 924-929. ( DOI )

  19. Imaizumi Yuki, Goda Tatsuro, Matsumoto Akira, Miyahara Yuji: Identification of types of membrane injuries and cell death using whole cell-based proton-sensitive field-effect transistor systems ANALYST. 2017.09; 142 (18): 3451-3458. ( DOI )

  20. Matsumoto A., Stephenson-Brown A. J., Khan T., Miyazawa T., Cabral H., Kataoka K., Miyahara Y.: Heterocyclic boronic acids display sialic acid selective binding in a hypoxic tumor relevant acidic environment CHEMICAL SCIENCE. 2017.09; 8 (9): 6165-6170. ( DOI )

  21. Kanemoto K, Sugimura Y, Shimizu S, Yoshida S, Hosoya T: Rhodium-catalyzed odorless synthesis of diaryl sulfides from borylarenes and #IS#IR-aryl thiosulfonates. Chem Commun. 2017.09; 53 (77): 10640-10643. ( PubMed , DOI )

  22. Sakaguchi H, Uetake Y, Ohashi M, Niwa T, Ogoshi S, Hosoya T: Copper-Catalyzed Regioselective Monodefluoroborylation of Polyfluoroalkenes en Route to Diverse Fluoroalkenes. J Am Chem Soc. 2017.09; 139 (36): 12855-12862. ( PubMed , DOI )

  23. Nakano-Kobayashi A, Awaya T, Kii I, Sumida Y, Okuno Y, Yoshida S, Sumida T, Inoue H, Hosoya T, Hagiwara M: Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice. Proc Natl Acad Sci USA. 2017.09; 114 (38): 10268-10273. ( PubMed , DOI )

  24. Ikura Teikichi, Ito Nobutoshi: タウタンパク質に対するPin1由来のプロテアーゼの活性の定量的評価(Quantitative evaluation of activity of a protease derived from Pin1 for tau protein) 生物物理. 2017.08; 57 (Suppl.1-2): S315. ( 医中誌 )

  25. Numoto Nobutaka, Akatsu Chizuru, Shinagawa Kenro, Tsubata Takeshi, Ito Nobutoshi: B細胞抑制性因子CD72の分子表面電荷分布によるリガンド結合制御機構(Charge distribution regulates the ligand-binding affinity of B cell inhibitory receptor CD72) 生物物理. 2017.08; 57 (Suppl.1-2): S276. ( 医中誌 )

  26. Jun Negishi, Yuka Omori, Mami Shindo, Hayate Takanashi, Shiori Musha, Suminori Nagayama, Jun Hirayama, Hiroshi Nishina, Takashi Nakakura, Chihiro Mogi, Koichi Sato, Fumikazu Okajima, Yuta Mochimaru, Hideaki Tomura: Manganese and cobalt activate zebrafish ovarian cancer G-protein-coupled receptor 1 but not GPR4. J. Recept. Signal Transduct. Res.. 2017.08; 37 (4): 401-408. ( PubMed , DOI )

  27. Tokiwa Yamasaki, Norie Deki-Arima, Asahito Kaneko, Norio Miyamura, Mamiko Iwatsuki, Masato Matsuoka, Noriko Fujimori-Tonou, Yoshimi Okamoto-Uchida, Jun Hirayama, Jamey D Marth, Yuji Yamanashi, Hiroshi Kawasaki, Koji Yamanaka, Josef M Penninger, Shigenobu Shibata, Hiroshi Nishina: Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7. Sci Rep. 2017.08; 7 (1): 7348. ( PubMed , DOI )

  28. Noriko Sato, Katsuko Sudo, Masayo Mori, Chihiro Imai, Masaaki Muramatsu, Masahiro Sugimoto: Early gestational maternal low-protein diet diminishes hepatic response to fasting in young adult male mice. Sci Rep. 2017.08; 7 (1): 9812. ( PubMed , DOI )

  29. Yumiko Oishi, Shinichiro Hayashi, Takayuki Isagawa, Motohiko Oshima, Atsushi Iwama, Shigeki Shimba, Hitoshi Okamura, Ichiro Manabe: Bmal1 regulates inflammatory responses in macrophages by modulating enhancer RNA transcription. Sci Rep. 2017.08; 7 (1): 7086. ( PubMed , DOI )

  30. Nomura Wataru, Matsumoto Daisuke, Hashimoto Tsukasa, Sugii Taisuke, Tamamura Hirokazu: Development of chemical-inducible artificial transcription factors based on sequence-specific DNA binders ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2017.08; 254

  31. Meguro T, Yoshida S, Hosoya T: Sequential Molecular Conjugation using Thiophene #IS#IR,#IS#IR-Dioxides Bearing a Clickable Functional Group. Chem Lett. 2017.08; 46 (8): 1137-1140. ( DOI )

  32. Kumpei Tanisawa, Nobuyoshi Hirose, Yasumichi Arai, Hiroshi Shimokata, Yoshiji Yamada, Hisashi Kawai, Motonaga Kojima, Shuichi Obuchi, Hirohiko Hirano, Hiroyuki Suzuki, Yoshinori Fujiwara, Yu Taniguchi, Shoji Shinkai, Kazushige Ihara, Maki Sugaya, Mitsuru Higuchi, Tomio Arai, Seijiro Mori, Motoji Sawabe, Noriko Sato, Masaaki Muramatsu, Masashi Tanaka: Inverse association between height-increasing alleles and extreme longevity in Japanese women. J. Gerontol. A Biol. Sci. Med. Sci.. 2017.08; ( PubMed , DOI )

  33. Khin Thet Thet Zaw , Sato Noriko, Ikeda Shinobu, Kaung Si Thu , Naka Mieno Makiko, Arai Tomio, Mori Seijiro, Furukawa Tetsushi, Sasano Tetsuo, Sawabe Motoji, Tanaka Masashi, Muramatsu Masaaki: ZFHX3遺伝子変異と心房細動、脳梗塞、肺血栓塞栓症との関連　剖検研究(Association of ZFHX3 gene variation with atrial fibrillation, cerebral infarction, and lung thromboembolism: An autopsy study) Journal of Cardiology. 2017.08; 70 (1-2): 180-184. ( 医中誌 )

  34. Nishiyama Y, Hazama Y, Yoshida S, Hosoya T: Synthesis of Unsymmetrical Tertiary Phosphine Oxides via Sequential Substitution Reaction of Phosphonic Acid Dithioesters with Grignard Reagents. Org Lett. 2017.07; 19 (14): 3899-3902. ( PubMed , DOI )

  35. Furubayashi T, Motohashi K, Wakao K, Matsuda T, Kii I, Hosoya T, Hayashi N, Sadaie M, Ishikawa F, Matsushita M, Fujiyoshi S: Three-Dimensional Localization of an Individual Fluorescent Molecule with Angstrom Precision. J Am Chem Soc. 2017.07; 139 (26): 8990-8994. ( PubMed , DOI )

  36. K Otsubo, H Goto, M Nishio, K Kawamura, S Yanagi, W Nishie, T Sasaki, T Maehama, H Nishina, K Mimori, T Nakano, H Shimizu, T W Mak, K Nakao, Y Nakanishi, A Suzuki: MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation. Oncogene. 2017.07; 36 (29): 4201-4211. ( PubMed , DOI )

  37. Kenta Iitani, Toshiyuki Sato, Munire Naisierding, Yuuki Hayakawa, Koji Toma, Takahiro Arakawa, Kohji Mitsubayashi: Fluorometric gas-imaging system (sniff-cam), using the extinction of NADH with an ADH reverse reaction, for acetaldehyde in the gas phase. Analyst. 2017.07; ( PubMed , DOI )

  38. Kenta Iitani, Po-Jen Chien, Takuma Suzuki, Koji Toma, Takahiro Arakawa, Yasuhiko Iwasaki, Kohji Mitsubayashi: Improved sensitivity of acetaldehyde biosensor by detecting ADH reverse reaction-mediated NADH fluoro-quenching for wine evaluation ACS Sensors. 2017.07; 2 (7): 940-946. ( PubMed , DOI )

  39. Ohashi N, Kobayashi R, Nomura W, Kobayakawa T, Czikora A, Herold B K, Lewin N E, Blumberg P M, Tamamura H: Synthesis and Evaluation of Dimeric Derivatives of Diacylglycerol-Lactones as Protein Kinase C Ligands. Bioconjugate Chem. 2017.07; ( DOI )

  40. Takuya Kobayakawa, Hirokazu Tamamura: Stereoselective synthesis of Xaa-Yaa type (Z)-chloroalkene dipeptide isosteres via efficient utilization of organocopper reagents mediated allylic alkylation Tetrahedron. 2017.07; 73 (30): 4464-4471. ( DOI )

  41. Kobayakawa Takuya, Tamamura Hirokazu: Stereoselective synthesis of Xaa-Yaa type (Z)-chloroalkene dipeptide isosteres via efficient utilization of organocopper reagents mediated allylic alkylation TETRAHEDRON. 2017.07; 73 (30): 4464-4471. ( DOI )

  42. Norio Miyamura, Shoji Hata, Tohru Itoh, Minoru Tanaka, Miki Nishio, Michiko Itoh, Yoshihiro Ogawa, Shuji Terai, Isao Sakaida, Akira Suzuki, Atsushi Miyajima, Hiroshi Nishina: YAP determines the cell fate of injured mouse hepatocytes in vivo. Nat Commun. 2017.07; 8 16017. ( PubMed , DOI )

  43. Tsuyoshi Kimura, Naoko Nakamura, Kanji Umeda, Yoshihide Hashimoto, Akio Kishida: Capture and release of cells using a temperature-responsive surface that immobilizes an antibody through DNA duplex formation. Journal of Biomaterials Science, Polymer Edition. 2017.07; 28 (10-12): 1172-1182. ( PubMed , DOI )

  44. Sumida Y, Sumida T, Hosoya T: Nickel-Catalyzed Reductive Cross-Coupling of Aryl Triflates and Nonaflates with Alkyl Iodides. Synthesis. 2017.06; 49 (16): 3590-3601. ( DOI )

  45. Yukichi Horiguchi, Tatsuro Goda, Akira Matsumoto, Hiroaki Takeuchi, Shoji Yamaoka, Yuji Miyahara: Direct and label-free influenza virus detection based on multisite binding to sialic acid receptors. Biosens Bioelectron. 2017.06; 92 234-240. ( PubMed , DOI )

  46. Kohji Mitsubayashi: Body cavity sensors offer monitoring solutions in daily medicine TMDU Research Activities. 2017.06; 13.

  47. Nakamura Y, Yoshida S, Hosoya T: Facile Synthesis of Phthalides from Methyl #Iortho#IR-Iodobenzoates and Ketones via an Iodine–Magnesium Exchange Reaction Using a Silylmethyl Grignard Reagent. Chem Lett. 2017.06; 46 (6): 858-861. ( DOI )

  48. Toshihiro Imada, Jin Kai, Izuta Yusuke, Nakamura Shigeru, Adachi Takahiro, Tsubota Kazuo: In vivo dynamics of Ca2+-dependent myoepithelial contraction in lacrimal gland INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2017.06; 58 (8):

  49. Toshihiro Imada, Jin Kai, Izuta Yusuke, Nakamura Shigeru, Adachi Takahiro, Tsubota Kazuo: In vivo dynamics of Ca2+-dependent myoepithelial contraction in lacrimal gland INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2017.06; 58 (8):

  50. Yukichi Horiguchi, Tatsuro Goda, Akira Matsumoto, Hiroaki Takeuchi, Shoji Yamaoka, Yuji Miyahara: Direct and Label-Free Influenza Virus Detection Based on Multisite Binding to Sialic Acid Receptors Biosens. Bioelectron.. 2017.06; 92 234-240.

  51. Jun Negishi, Yoshihide Hashimoto, Akitatsu Yamashita, Yongwei Zhang, Tsuyoshi Kimura, Akio Kishida, Seiichi Funamoto: Evaluation of small-diameter vascular grafts reconstructed from decellularized aorta sheets. J Biomed Mater Res A. 2017.05; 105 (5): 1293-1298. ( PubMed , DOI )

  52. Po-Jen Chien, Takuma Suzuki, Masato Tsujii, Ming Ye, Koji Toma, Takahiro Arakawa, Yasuhiko Iwasaki, Kohji Mitsubayashi: Bio-sniffer (gas-phase biosensor) with secondary alcohol dehydrogenase (S-ADH) for determination of isopropanol in exhaled air as a potential volatile biomarker. Biosensors and Bioelectronics. 2017.05; 91 341-346. ( PubMed , DOI )

  53. Hiraku Ohno, Kazuki Takeda, Satomi Niwa, Tomotaka Tsujinaka, Yuya Hanazono, Yu Hirano, Kunio Miki: Crystallographic characterization of the high-potential iron-sulfur protein in the oxidized state at 0.8 Å resolution. PLoS One. 2017.05; 12 (5): e0178183. ( PubMed , DOI )

  54. Yoshida S, Nagai A, Uchida K, Hosoya T: Enhancing the Synthetic Utility of 3-Haloaryne Intermediates by their Efficient Generation from Readily Synthesizable #Iortho#IR-Iodoaryl Triflate-type Precursors. Chem Lett. 2017.05; 46 (5): 733-736. ( DOI )

  55. Sako Y, Ninomiya K, Okuno Y, Toyomoto M, Nishida A, Koike Y, Ohe K, Kii I, Yoshida S, Hashimoto N, Hosoya T, Matsuo M, Hagiwara M: Development of an orally available inhibitor of CLK1 for skipping a mutated dystrophin exon in Duchenne muscular dystrophy. Sci Rep. 2017.05; 7 46126. ( PubMed , DOI )

  56. Niwa T, Ochia H, Hosoya T: Copper-Catalyzed #Iipso#IR-Borylation of Fluoroarenes. ACS Catal. 2017.05; 7 (7): 4535-4541. ( DOI )

  57. Taro Watabe, Takashi Nagaishi, Akinori Hosoya, Nisha Jose, Arisa Tokai, Yudai Kojima, Takahiro Adachi, Mamoru Watanabe: THE LACK OF SECRETED IGA SPONTANEOUSLY INDUCES THE MUCOSAL INFLAMMATION SPECIFICALLY IN THE ILEUM GASTROENTEROLOGY. 2017.04; 152 (5): S1004.

  58. Wenfeng H., Goda T., Takeuchi H., Yamaoka S., Horiguchi Y., Akira M., and Miyahara Y.: Specific Recognition of Human Influenza Virus with PEDOT Bearing Sialic Acid-Terminated Trisaccharides. ACS Applied Materials & Interfaces. 2017.04; 9 (16): 14162-14170. ( PubMed , DOI )

  59. Sariya Dechamethakun, Noriko Sato, Shinobu Ikeda, Motoji Sawabe, Seijiro Mori, Yoshiji Yamada, Masashi Tanaka Masaaki Muramatsu and Tomio Arai: Association of Macrophage Capping Protein (CAPG) Arg335His Polymorphism and Cancer Susceptibility in the Elderly Japanese Journal of Gerontology and Geriatric Research. 2017.04; 6 (2): 417.

  60. Ratanaporncharoen Chindanai, Tabata Miyuki, Goda Tatsuro, Matsumoto Akira, Miyahara Yuji, Ishihara Noboru, Masu Kazuya: 実地モニタリングのための小型化ワイヤレスpHセンサー(Miniaturized wireless pH sensor for on-site monitoring) 生体医歯工学共同研究拠点成果報告書. 2017.04; 平成28年度 49. ( 医中誌 )

  61. Matsumoto Akira, Sato Shohei, Sakamaki Tomoko, Sanjo Mai, Tabata Miyuki, Goda Tatsuro, Asoh Taka-Aki, Kikuchi Akihiko, Miyahara Yuji: Demonstration of thermo-sensitive tetra-gel with implication for facile and versatile platform for a new class of smart gels JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION. 2017.04; 28 (10-12 SI): 1000-1009. ( DOI )

  62. Hiroki Maeda, Hiroshi Kobayashi, Takayuki Miyahara, Yoshihide Hashimoto, Kazunari Akiyoshi, Shohei Kasugai: Effects of a polysaccharide nanogel-crosslinked membrane on wound healing J Biomed Mater Res Part B Appl Biomater. 2017.04; 105 (3): 544-550. ( PubMed , DOI )

  63. Kobayashi K, Mizuguchi T, Hattori Y, Ohara N, Ninomiya R, Iida M, Ooe H, Yamazaki Y, Takata M, Tamamura H, Akaji K: Effects of Replacement and Addition of an Amino Acid Contained in a Cyclic Peptide Corresponding to a β-Hairpin Loop Sequence of Human EGF Receptor. J. Pept. Sci. 2017.04; ( DOI )

  64. THE LACK OF SECRETED IGA SPONTANEOUSLY INDUCES THE MUCOSAL INFLAMMATION SPECIFICALLY IN THE ILEUM 2017.04; 152 (5): S1004.

  65. Meguro T, Yoshida S, Hosoya T : Aromatic Azido-selective Reduction via the Staudinger Reaction Using Tri-#In#IR-butylphosphonium Tetrafluoroborate with Triethylamine. Chem Lett. 2017.04; 46 (4): 473-476. ( DOI )

  66. Takahiro Arakawa, Toshiyuki Sato, Kenta Iitani, Koji Toma, Kohji Mitsubayashi: Fluorometric biosniffer camera “Sniff-cam” for direct imaging of gaseous ethanol in breath and transdermal vapor Analytical Chemistry. 2017.04; 89 (8): 4495-4501. ( PubMed , DOI )

  67. Wenfeng Hai, Tatsuro Goda, Hiroaki Takeuchi, Shoji Yamaoka, Yukichi Horiguchi, Akira Matsumoto, Yuji Miyahara: Specific Recognition of Human Influenza Virus with PEDOT Bearing Sialic Acid-Terminated Trisaccharides ACS Appl. Mater. Interfaces. 2017.04; 9 14162-14170.

  68. Akira Matsumoto, Shohei Sato, Tomoko Sakamaki, Mai Sanjo, Miyuki Tabata, Tatsuro Goda, Taka-aki Asoh, Akihiko Kikuchi, Yuji Miyahara: Demonstration of Thermo-Sensitive Tetra-Gel with Implication for Facile and Versatile Platform for a New Class of Smart Gels J. Biomater. Sci. Polym. Ed.. 2017.04; 28 1000-1009.

  69. Seiichiro Mori, Takamasa Takeuchi, Yoshiyuki Ishii, Takashi Yugawa, Tohru Kiyono, Hiroshi Nishina, Iwao Kukimoto: Human Papillomavirus 16 E6 Upregulates APOBEC3B via the TEAD Transcription Factor. J. Virol.. 2017.03; 91 (6): ( PubMed , DOI )

  70. Imaizumi Yuki, Goda Tatsuro, Schaffhauser Daniel F., Okada Jun-ichi, Matsumoto Akira, Miyahara Yuji: Proton-sensing transistor systems for detecting ion leakage from plasma membranes under chemical stimuli ACTA BIOMATERIALIA. 2017.03; 50 502-509. ( DOI )

  71. Kumpei Tanisawa, Yasumichi Arai, Nobuyoshi Hirose, Hiroshi Shimokata, Yoshiji Yamada, Hisashi Kawai, Motonaga Kojima, Shuichi Obuchi, Hirohiko Hirano, Hideyo Yoshida, Hiroyuki Suzuki, Yoshinori Fujiwara, Kazushige Ihara, Maki Sugaya, Tomio Arai, Seijiro Mori, Motoji Sawabe, Noriko Sato, Masaaki Muramatsu, Mitsuru Higuchi, Yao-Wen Liu, Qing-Peng Kong, Masashi Tanaka: Exome-wide Association Study Identifies CLEC3B Missense Variant p.S106G as Being Associated With Extreme Longevity in East Asian Populations. J. Gerontol. A Biol. Sci. Med. Sci.. 2017.03; 72 (3): 309-318. ( PubMed , DOI )

  72. Y. Sawa, G. Matsumiya, K. Matsuda, E. Tatsumi, T. Abe, K. Fukunaga, S. Ichiba, A. Kishida, 他: Journal of Artificial Organs 2016:the year in review J. Artif Organs. 2017.03; 20 (1): 1-7.

  73. Takano Hikaru, Narumi Tetsuo, Nomura Wataru, Tamamura Hirokazu: Microwave-Assisted Synthesis of Azacoumarin Fluorophores and the Fluorescence Characterization JOURNAL OF ORGANIC CHEMISTRY. 2017.03; 82 (5): 2739-2744. ( PubMed , DOI )

  74. Uchida K, Yoshida S, Hosoya T: Three-Component Coupling of Triflyloxy-Substituted Benzocyclobutenones, Organolithium Reagents, and Arynophiles Promoted by Generation of Aryne via Carbon-Carbon Bond Cleavage. Org Lett. 2017.03; 19 (5): 1184-1187. ( PubMed , DOI )

  75. Ryo Harada, Seiichi Funamoto, Jun Negishi, Yusuke Kasahara, Tsuyoshi Kimura, Kwangwoo Nam, Toru masuzawa, Akio Kishida, Tetsuya Higami: Novel Adhension device for living tissue The Sapporo Medhical Journal. 2017.03; (85): 57-65.

  76. Yuki Imaizumi, Tatsuro Goda, Daniel F. Schaffhauser, Jun-ichi Okada, Akira Matsumoto, Yuji Miyahara: Proton-Sensing Transistor Systems for Detecting Ion Leakage from Plasma Membranes under Chemical Stimuli Acta Biomater.. 2017.03; 50 502-509.

  77. Yumiko Oishi, Nathanael J Spann, Verena M Link, Evan D Muse, Tobias Strid, Chantle Edillor, Matthew J Kolar, Takashi Matsuzaka, Sumio Hayakawa, Jenhan Tao, Minna U Kaikkonen, Aaron F Carlin, Michael T Lam, Ichiro Manabe, Hitoshi Shimano, Alan Saghatelian, Christopher K Glass: SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism. Cell Metab.. 2017.02; 25 (2): 412-427. ( PubMed , DOI )

  78. Takano T, Narumi T, Nomura W, Tamamura H: Microwave-Assisted Synthesis of Azacoumarin Fluorophores and the Fluorescence Characterization. J. Org. Chem. 2017.02; 82 (5): 2739-2744.

  79. Ochiai H, Uetake Y, Niwa T, Hosoya T: Rhodium-Catalyzed Decarbonylative Borylation of Aromatic Thioesters for Facile Diversification of Aromatic Carboxylic Acids. Angew Chem Int Ed. 2017.02; 56 (9): 2482-2486. ( PubMed , DOI )

  80. Morita T, Nishiyama Y, Yoshida S, Hosoya T: Facile Synthesis of Multisubstituted Benzo[#Ib#IR]furans via 2,3-Disubstituted 6,7-Furanobenzynes Generated from #Iortho#IR-Iodoaryl Triflate-type Precursors. Chem Lett. 2017.01; 46 (1): 118-121. ( DOI )

  81. Morita T, Yoshida S, Kondo M, Matsushita T, Hosoya T: Facile Diversification of Simple Benzo[#Ib#IR]thiophenes via Thienobenzyne Intermediates. Chem Lett. 2017.01; 46 (1): 81-84. ( DOI )

  82. Yoshida S, Nakajima H, Uchida K, Yano T, Kondo M, Matsushita T, Hosoya T: Reactions of Arynes with Sulfoximines: Formal Sulfinylamination vs. #IN#IR-Arylation. Chem Lett. 2017.01; 46 (1): 77-80. ( DOI )

  83. Yoichi Asaoka, Hiroshi Nishina, Makoto Furutani-Seiki: YAP is essential for 3D organogenesis withstanding gravity. Dev. Growth Differ.. 2017.01; 59 (1): 52-58. ( PubMed , DOI )

  84. Miyuki Tabata, Yurika Katayama, Fahmida Mannan, Ayaka Seichi, Koji Suzuki, Tatsuro Goda, Akira Matsumoto, Yuji Miyahara: Label-free and Electrochemial Detection of Nucleic Acids Based on Isothermal Amplification in Combination with Solid-state pH Sensor 2017.01; 168 419-422.

  85. Miyuki Tabata, Chindanai Ratanaporncharoen, Aoi Asano, Yuichi Kitasako, Masaomi Ikeda, Tatsuro Goda, Akira Matsumoto, Junji Tagami, Yuji Miyahara: Miniaturized Ir/IrOx pH Sensor for Quantitative Diagnosis of Dental Caries Procedia Eng.. 2017.01; 168 598-601.

  86. Tanaka T, Aoki T, Nomura W, Tamamura H : Bivalent 14-mer Peptide Ligands of CXCR4 with Polyproline Linkers with Anti-Chemotactic Activity against Jurkat Cells. J. Pept. Sci. 2017.01; ( DOI )

  87. Mizuguchi T, Ohashi N, Matsumoto D, Hashimoto C, Nomura W, Yamamoto N, Murakami T, Tamamura: Development of Anti-HIV Peptides Based on a Viral Capsid Protein. Biopolymers: Peptide Science. 2017.01; 108 (1): ( DOI )

  88. Jun Negishi, Yoshihide Hashimoto, Akitatsu Yamashita, Tsuyoshi Kimura, Akio Kishida, Seiichi Funamoto: Histological structure affects recellularization of decellularized arteries. Mater Sci Eng C Mater Biol Appl. 2017.01; 70 (Pt 1): 450-455. ( PubMed , DOI )

  89. Satomi Inaba, Nobutaka Numoto, Shuhei Ogawa, Hisayuki Morii, Teikichi Ikura, Ryo Abe, Nobutoshi Ito, Masayuki Oda: Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins. J. Biol. Chem.. 2017.01; 292 (3): 1052-1060. ( PubMed , DOI )

  90. Gunce E. Cinay, Pelin Erkoc, Mohammad Alipour, Yoshihide Hashimoto, Yoshihiro Sasaki, Kazunari Akiyoshi, Seda Kizilel: Nanogel-integrated pH responsive composite hydrogels for controlled drug delivery ACS Biomaterials Science and Engineering. 2017.01; 3 (3): 370-380. ( DOI )

  91. Asaoka Yoichi, Nishina Hiroshi, Furutani-Seiki Makoto: 【発生時のサイズ】YAPは重力に抵抗性の3D器官形成にとって必須である(【Size in development】YAP is essential for 3D organogenesis withstanding gravity) Development, Growth & Differentiation. 2017.01; 59 (1): 52-58. ( 医中誌 )

  92. Tatsuro Goda, Yuji Miyahara: Calcium-Independent Binding of Human C-Reactive Protein to Lysophosphatidylcholine in Supported Planar Phospholipid Monolayers Acta Biomater.. 2017.01; 48 206-214. ( DOI )

  93. Kulkarni Manjiri R., Islam Monirul, Numoto Nobutaka, Elahi Montasir, Ito Nobutoshi, Kuroda Yutaka: Crystallographic studies of sero-specific Dengue ED3 immune response ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES. 2017; 73 A404. ( DOI )

  94. Kulkarni Manjiri Ravindra, Islam Monirul, Numoto Nobutaka, Ito Nobutoshi, Kuroda Yutaka: Crystal structures of dengue virus protein revealed ED3 sero-specificity ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES. 2017; 73 C394. ( DOI )

  1. Yoshida S, Nakamura Y, Uchida K, Hazama Y, Hosoya T: Aryne Relay Chemistry en Route to Aminoarenes: Synthesis of 3-Aminoaryne Precursors via Regioselective Silylamination of 3-(Triflyloxy)arynes.. Org Lett. 2016.12; 18 (23): 6212-6215. ( PubMed , DOI )

  2. Ochiai H, Niwa T, Hosoya T: Stereoinversion of Stereocongested Carbocyclic Alcohols via Triflylation and Subsequent Treatment with Aqueous #IN#IR,#IN#IR-Dimethylformamide. Org Lett. 2016.12; 18 (23): 5982-5985. ( PubMed , DOI )

  3. Yuko Maeda, Noriko Sato, Makiko Naka-Mieno, Seijiro Mori, Tomio Arai, Masashi Tanaka, Masaaki Muramatsu, Motoji Sawabe: Association of non-synonymous variants in WIPF3 and LIPA genes with abdominal aortic aneurysm: an autopsy study. J Geriatr Cardiol. 2016.12; 13 (12): 960-967. ( PubMed , DOI )

  4. T. Kimura, N. Nakamura, N. Sasaki, Y. Hashimoto, S. Sakaguchi, S. Kimura, A. Kishida: Capture and release of target cells using a surface that immobilizes an antibody via desthiobiotin–avidin interaction Sens Mater. 2016.12; 28 (12): 1255-1263.

  5. Khin Thet Thet Zaw, Noriko Sato, Shinobu Ikeda, Kaung Si Thu, Makiko Naka Mieno, Tomio Arai, Seijiro Mori, Tetsushi Furukawa, Tetsuo Sasano, Motoji Sawabe, Masashi Tanaka, Masaaki Muramatsu: Association of ZFHX3 gene variation with atrial fibrillation, cerebral infarction, and lung thromboembolism: An autopsy study. J Cardiol. 2016.12; ( PubMed , DOI )

  6. N. Nakamura, T. Kimura, A. Kishida: Overview of the development, applications, and future perspectives of decellularized tissues and organs ACS Biomater Sci Eng. 2016.11; 3 (7): 1236-1244. ( DOI )

  7. Doi H, Sato K, Shindou H, Sumi K, Koyama H, Hosoya T, Watanabe Y, Ishii S, Tsukada H, Nakanishi K, Suzuki M: Blood-brain barrier permeability of ginkgolide: Comparison of the behavior of PET probes 7α-[#U18#URF]fluoro- and 10-#IO#IR-#Ip#IR-[#U11#URC]methylbenzyl ginkgolide B in monkey and rat brains. Bioorg Med Chem. 2016.11; 24 (21): 5148-5157. ( PubMed , DOI )

  8. Okamoto-Uchida Y, Yu R, Miyamura N, Arima N, Ishigami-Yuasa M, Kagechika H, Yoshida S, Hosoya T, Nawa M, Kasama T, Asaoka Y, Alois RW, Elling U, Penninger JM, Nishina S, Azuma N, Nishina H: The mevalonate pathway regulates primitive streak formation via protein farnesylation. Sci Rep. 2016.11; 6 37697. ( PubMed , DOI )

  9. Sumida Y, Sumida T, Hashizume D, Hosoya T: Preparation of Aryne-Nickel Complexes from #Iortho#IR-Borylaryl Triflates. Org Lett. 2016.11; 18 (21): 5600-5603. ( PubMed , DOI )

  10. Chizuru Akatsu, Kenro Shinagawa, Nobutaka Numoto, Zhihong Liu, Ayse Konuskan Ucar, Mohammad Aslam, Shirly Phoon, Takahiro Adachi, Koji Furukawa, Nobutoshi Ito, Takeshi Tsubata: CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP. J. Exp. Med.. 2016.11; 213 (12): 2691-2706. ( PubMed , DOI )

  11. Miyuki Tabata, Chindanai Ratanaporncharoen, Aoi Asano, Yuichi Kitasako, Masaomi Ikeda, Tatsuro Goda, Akira Matsumoto, Junji Tagami, Yuji Miyahara: Miniaturized Ir/IrOx pH Sensor for Quantitative Diagnosis of Dental Caries Procedia Eng.. 2016.11; 168 ( DOI )

  12. Miyuki Tabata, Yurika Katayama, Fahmida Mannan, Ayaka Seichi, Koji Suzuki, Tatsuro Goda, Akira Matsumoto, Yuji Miyahara: Label-free and Electrochemial Detection of Nucleic Acids Based on Isothermal Amplification in Combination with Solid-state pH Sensor Procedia Eng.. 2016.11; 168 419-422. ( DOI )

  13. Yuya Hanazono, Kazuki Takeda, Kunio Miki: Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein. Sci Rep. 2016.10; 6 34654. ( PubMed , DOI )

  14. Shinichiro Hayashi, Ichiro Manabe, Yumi Suzuki, Frédéric Relaix, Yumiko Oishi: Klf5 regulates muscle differentiation by directly targeting muscle-specific genes in cooperation with MyoD in mice. Elife. 2016.10; 5 ( PubMed , DOI )

  15. Yoshida S, Yano T, Nishiyama Y, Misawa Y, Kondo M, Matsushita T, Igawa K, Tomooka K, Hosoya T: Thiazolobenzyne: a versatile intermediate for multisubstituted benzothiazoles. Chem Commun. 2016.09; 52 (75): 11199-11202. ( PubMed , DOI )

  16. Tanaka T, Okuyama-Dobashi K, Murakami S, Chen W, Okamoto T, Ueda K, Hosoya T, Matsuura Y, Ryo A, Tanaka Y, Hagiwara M, Moriishi K: Inhibitory effect of CDK9 inhibitor FIT-039 on hepatitis B virus propagation. Antiviral Res. 2016.09; 133 156-164. ( PubMed , DOI )

  17. K. Akazawa, K. Iwasaki, M. Nagata, N. Yokoyama, H. Ayame, K. Yamaki, Y. Tanaka, I. Honda, C. Morioka, T. Kimura, M. Komaki, A. Kishida, Y. Izumi, I. Morita: Double-layered cell transfer technology for bone regeneration Scientific Reports. 2016.09; 6 33286. ( DOI )

  18. Tomomi Imamura, Kyota Fujita, Kazuhiko Tagawa, Teikichi Ikura, Xigui Chen, Hidenori Homma, Takuya Tamura, Ying Mao, Juliana Bosso Taniguchi, Kazumi Motoki, Makoto Nakabayashi, Nobutoshi Ito, Kazunori Yamada, Kentaro Tomii, Hideyuki Okano, Julia Kaye, Steven Finkbeiner, Hitoshi Okazawa: Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries. Sci Rep. 2016.09; 6 33861. ( PubMed , DOI )

  19. Takuya Kobayakawa, Hirokazu Tamamura: Efficient synthesis of Xaa-Gly type (Z)-chloroalkene dipeptide isosteres via organocuprate mediated reduction Tetrahedron. 2016.08; 72 (32): 4968-4971. ( DOI )

  20. S. Yoshikawa, M. Oh-hora, T. Adachi, Y. Yamanishi, H. Karasuyama: Stromal interaction molecule-1/2 plays essential role in basophil activation and development of IgE-mediated chronic allergic inflammation EUROPEAN JOURNAL OF IMMUNOLOGY. 2016.08; 46 99.

  21. Controlled Generation of 3-Triflyloxyarynes. Synthesis. 2016.08; 48 (23): 4099-4109. ( DOI )

  22. Yoshida S, Shimomori K, Kim Y, Hosoya T: Single C-F Bond Cleavage of Trifluoromethylarenes with an #Iortho#IR-Silyl Group. Angew Chem Int Ed Engl. 2016.08; 55 (35): 10406-10409. ( PubMed , DOI )

  23. Kaung Si Thu, Noriko Sato, Shinobu Ikeda, Makiko Naka-Mieno, Tomio Arai, Seijiro Mori, Motoji Sawabe, Masaaki Muramatsu, Masashi Tanaka: Association of polymorphisms of the transporter associated with antigen processing (TAP2) gene with pulmonary tuberculosis in an elderly Japanese population. APMIS. 2016.08; 124 (8): 675-680. ( PubMed , DOI )

  24. Tatsuro Goda, Yuji Miyahara: Engineered Zwitterionic Phosphorylcholine Monolayers for Elucidating Multivalent Binding Kinetics of C-reactive Protein Acta Biomater.. 2016.08; 40 46-53. ( DOI )

  25. Yoshida S, Morita T, Hosoya T: Synthesis of Diverse Benzotriazoles from Aryne Precursors Bearing an Azido Group via Inter- and Intramolecular Cycloadditions. Chem Lett. 2016.07; 45 (7): 726-728. ( DOI )

  26. Yumiko Oishi, Ichiro Manabe: Macrophages in age-related chronic inflammatory diseases Aging and Mechanisms of Disease. 2016.07; 2 16018. ( DOI )

  27. H. Suzuki, Y. Ito, M. Shinohara, S. Yamashita, S. Ichinose, A. Kishida, T. Oyaizu, T. Kayama, R. Nakamichi, N. Koda, K. Yagishita, MK. Lotz, A. Okawa, H. Asahara: Gene targeting of the transcription factor mohawk in rats causes heterotopic ossification of achilles tendon via failed tenogenesis Proc Natl Acad Sci USA. 2016.07; 113 (28): 7840-7845. ( DOI )

  28. Yuki Imaizumi, Tatsuro Goda, Yutaro Toya, Akira Matsumoto, Yuichi Miyahara: Oleyl Group-functionalized Insulating Gate Transistors for Measuring Extracellular pH of Floating Cells Sci. Technol. Adv. Mater.. 2016.07; 17 337-345. ( DOI )

  29. Uetake Y, Niwa T, Hosoya T: Rhodium-Catalyzed #Iipso#IR-Borylation of Alkylthioarenes via C-S Bond Cleavage. Org Lett. 2016.06; 18 (11): 2758-2761. ( PubMed , DOI )

  30. Takahiro Arakawa, Kohji Mitsubayashi: Cavitas sensors: Contact lens type sensors & mouthguard sensors Electroanalysis. 2016.06; 28 1170-1187.

  31. Takanori Chiba, Erika Ishihara, Norio Miyamura, Rika Narumi, Mihoko Kajita, Yasuyuki Fujita, Akira Suzuki, Yoshihiro Ogawa, Hiroshi Nishina: MDCK cells expressing constitutively active Yes-associated protein (YAP) undergo apical extrusion depending on neighboring cell status. Sci Rep. 2016.06; 6 28383. ( PubMed , DOI )

  32. Shunta Nagashima, Junichi Maruyama, Shodai Kawano, Hiroaki Iwasa, Kentaro Nakagawa, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Hiroshi Nishina, Yutaka Hata: Validation of chemical compound library screening for transcriptional co-activator with PDZ-binding motif inhibitors using GFP-fused transcriptional co-activator with PDZ-binding motif. Cancer Sci.. 2016.06; 107 (6): 791-802. ( PubMed , DOI )

  33. Yuya Hanazono, Kazuki Takeda, Kunio Miki: Characterization of the Nqo5 subunit of bacterial complex I in the isolated state. FEBS Open Bio. 2016.06; 6 (7): 687-695. ( PubMed , DOI )

  34. Rumi Hachiya, Takuya Shiihashi, Ibuki Shirakawa, Yorihiro Iwasaki, Yoshihiro Matsumura, Yumiko Oishi, Yukiteru Nakayama, Yoshihiro Miyamoto, Ichiro Manabe, Kozue Ochi, Miyako Tanaka, Nobuhito Goda, Juro Sakai, Takayoshi Suganami, Yoshihiro Ogawa: The H3K9 methyltransferase Setdb1 regulates TLR4-mediated inflammatory responses in macrophages. Sci Rep. 2016.06; 6 28845. ( PubMed , DOI )

  35. Yoshihide Hashimoto, Shinya Hattori, Shuji Sasaki, Takako Honda, Tsuyoshi Kimura, Seiichi Funamoto, Hisatoshi Kobayashi, Akio Kishida: Ultrastructural analysis of the decellularized cornea after interlamellar keratoplasty and microkeratome-assisted anterior lamellar keratoplasty in a rabbit model. Scientific Reports . 2016.06; 6 27734. ( PubMed , DOI )

  36. Yoichi Asaoka, Yoko Nagai, Misako Namae, Makoto Furutani-Seiki, Hiroshi Nishina: SLC7 family transporters control the establishment of left-right asymmetry during organogenesis in medaka by activating mTOR signaling. Biochem. Biophys. Res. Commun.. 2016.05; 474 (1): 146-153. ( PubMed , DOI )

  37. Seichi Ayaka, Kozuka Nanami, Kashima Yuko, Tabata Miyuki, Goda Tatsuro, Matsumoto Akira, Iwasawa Naoko, Citterio Daniel, Miyahara Yuji, Suzuki Koji: Real-time Monitoring and Detection of Primer Generation-Rolling Circle Amplification of DNA Using an Ethidium Ion-selective Electrode ANALYTICAL SCIENCES. 2016.05; 32 (5): 505-510.

  38. Toshiyasu Goto, Junhei Matsuzawa, Shun-Ichiro Iemura, Tohru Natsume, Hiroshi Shibuya: WDR26 is a new partner of Axin1 in the canonical Wnt signaling pathway. FEBS Lett.. 2016.05; 590 (9): 1291-1303. ( PubMed , DOI )

  39. Y. Suwa, K. Nam, K. Ozeki, T. Kimura, A. Kishida, T. Masuzawa: Thermal denaturation behavior of collagen fibrils in wet and dry environment J Biomed Mater Res Part B: Appl Biomater. 2016.04; 104 (3): 538-545. ( DOI )

  40. Takashi Fukuzono, Strahil Iv Pastuhov, Okinobu Fukushima, Chun Li, Ayuna Hattori, Shun-Ichiro Iemura, Tohru Natsume, Hiroshi Shibuya, Hiroshi Hanafusa, Kunihiro Matsumoto, Naoki Hisamoto: Chaperone complex BAG2-HSC70 regulates localization of Caenorhabditis elegans leucine-rich repeat kinase LRK-1 to the Golgi. Genes Cells. 2016.04; 21 (4): 311-324. ( PubMed , DOI )

  41. Ayaka Seichi, Nanami Kozuka, Yuko Kashima, Miyuki Tabata, Tatsuro Goda, Akira Matsumoto, Naoko Iwasawa, Daniel Citterio, Yuji Miyahara, Koji Suzuki: Real-time Monitoring and Detection of Primer Generation-Rolling Circle Amplification of DNA using an Ethidium Ion-Selective Electrode Anal. Sci.. 2016.03; 32 (5): 505-510. ( DOI )

  42. Daniel Schaffhauser, Michael Fine, Miyuki Tabata, Tatsuro Goda, Yuji Miyahara: Measurement of Rapid Amiloride-Dependent pH Changes at the Cell Surface Using a Proton-Sensitive Field-Effect Transistor Biosensors. 2016.03; 6 (2): 11. ( DOI )

  43. Y. Sawa，K. Matsuda，E. Tatsumi，G. Matsumiya，T. Tsukita，T.Abe，K. Fukunaga，A. Kishida，K. Kokubo，T. Masuzawa，A. Myoui，M. Nishimura，T. Nishimura，T. Nishinaka, E. Okamoto, S. Tokunaga, T. Tomo, Y. Yagi, T. Yamaoka: Journal of Artificial Organs 2015:the year in review Journal of Artificial Organs. 2016.03; 19 (1): 1-7. ( DOI )

  44. Koichi Fujisawa, Shuji Terai, Taro Takami, Naoki Yamamoto, Takahiro Yamasaki, Toshihiko Matsumoto, Kazuhito Yamaguchi, Yuji Owada, Hiroshi Nishina, Takafumi Noma, Isao Sakaida: Modulation of anti-cancer drug sensitivity through the regulation of mitochondrial activity by adenylate kinase 4. J. Exp. Clin. Cancer Res.. 2016.03; 35 48. ( PubMed , DOI )

  45. Yumiko Oishi, Ichiro Manabe: Integrated regulation of the cellular metabolism and function of immune cells in adipose tissue. Clin. Exp. Pharmacol. Physiol.. 2016.03; 43 (3): 294-303. ( PubMed , DOI )

  46. Sumio Hayakawa, Kieko Saito, Noriyuki Miyoshi, Tomokazu Ohishi, Yumiko Oishi, Mamoru Miyoshi, Yoriyuki Nakamura: Anti-Cancer Effects of Green Tea by Either Anti- or Pro- Oxidative Mechanisms. Asian Pac. J. Cancer Prev.. 2016.03; 17 (4): 1649-1654. ( PubMed )

  47. Tatsuro Goda, Eriko Yamada, Yurika Katayama, Miyuki Tabata, Akira Matsumoto, Yuji Miyahara: Potentiometric responses of ion-selective microelectrode with bovine serum albumin adsorption Biosensors and Bioelectronics. 2016.03; 77 208-214. ( DOI )

  48. Akira Matsumoto, Mai Yuasa, Hiroko Matsumoto, Mai Sanjo, Miyuki Tabata, Tatsuro Goda, Toru Hoshi, Takao Aoyagi, Yuji Miyahara: Boronate Functionalized Polymer Gel Based Insulin Delivery System with Improved Stability in Performance: A Comparative Structure-Function Study 2016.02; 45 (4): 460-462. ( DOI )

  49. Yoshihide Hashimoto, Sada-atsu Mukai, Shin-chi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi: Advanced artificial extracellular matrices using amphiphilic nanogel-crosslinked thin films to anchor adhesion proteins and cytokines ACS Biomater Sci Eng. 2016.02; 2 (3): 375-384.

  50. Manjiri R Kulkarni, Nobutaka Numoto, Nobutoshi Ito, Yutaka Kuroda: Modeling and experimental assessment of a buried Leu-Ile mutation in dengue envelope domain III. Biochem. Biophys. Res. Commun.. 2016.02; 471 (1): 163-168. ( PubMed , DOI )

  51. Miki Nishio, Keishi Sugimachi, Hiroki Goto, Jia Wang, Takumi Morikawa, Yosuke Miyachi, Yusuke Takano, Hiroki Hikasa, Tohru Itoh, Satoshi O Suzuki, Hiroki Kurihara, Shinichi Aishima, Andrew Leask, Takehiko Sasaki, Toru Nakano, Hiroshi Nishina, Yuji Nishikawa, Yoshitaka Sekido, Kazuwa Nakao, Kazuo Shin-Ya, Koshi Mimori, Akira Suzuki: Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice. Proc. Natl. Acad. Sci. U.S.A.. 2016.01; 113 (1): E71-E80. ( PubMed , DOI )

  52. Yusuke Nasu, Yoichi Asaoka, Misako Namae, Hiroshi Nishina, Hideaki Yoshimura, Takeaki Ozawa: Genetically Encoded Fluorescent Probe for Imaging Apoptosis in Vivo with Spontaneous GFP Complementation. Anal. Chem.. 2016.01; 88 (1): 838-844. ( PubMed , DOI )

  53. Yuya Hanazono, Kazuki Takeda, Satomi Niwa, Masahito Hibi, Naoya Takahashi, Tamotsu Kanai, Haruyuki Atomi, Kunio Miki: Crystal structures of chitin binding domains of chitinase from Thermococcus kodakarensis KOD1. FEBS Lett. 2016.01; 590 (2): 298-304. ( PubMed , DOI )

  54. Tomabechi Y, Hosoya T, Ehara H, Sekine S, Shirouzu M, Inouye S: Crystal structure of nanoKAZ: The mutated 19 kDa component of #IOplophorus#IR luciferase catalyzing the bioluminescent reaction with coelenterazine. Biochem Biophys Res Commun. 2016.01; 470 (1): 88-93. ( PubMed , DOI )

  55. Miyuki Tabata, Tatsuro Goda, Akira Matsumoto, Yuji Miyahara: Field-effect transistors for detection of biomolecular recognition Intelligent Nanosystems for Energy, Information and Biological Technologies. 2016.01; 2 13-25. ( DOI )

  56. Soichiro Yoshikawa, Takako Usami, Junichi Kikuta, Masaru Ishii, Tetsuo Sasano, Koji Sugiyama, Tetsushi Furukawa, Eiji Nakasho, Hiroshi Takayanagi, Thomas F Tedder, Hajime Karasuyama, Atsushi Miyawaki, Takahiro Adachi: Intravital imaging of Ca(2+) signals in lymphocytes of Ca(2+) biosensor transgenic mice: indication of autoimmune diseases before the pathological onset. Sci Rep. 2016.01; 6 18738. ( PubMed , DOI )

  57. Mizuguchi T, Harada S, Miura T, Ohashi N, Narumi T, Mori H, Irahara Y, Yamada Y, Nomura W, Matsushita S, Yoshimura K, Tamamura H: A Minimally Cytotoxic CD4 Mimic as an HIV Entry Inhibitor Bioorg. Med. Chem. Lett . 2016; 2 (26): 397-400.

  58. Adachi, T., Kakuta, S., Aihara, Y., Kamiya, T., Watanabe, Y., Osakabe, N., Hazato, N., Miyawaki, A., Yoshikawa, S., Usami, T., Karasuyama, H., Kimoto-Nira, H., Hirayama, K., M Tsuji, N.: Visualization of Probiotic-Mediated Ca(2+) Signaling in Intestinal Epithelial Cells In Vivo. Front Immunol. 2016; 7 601. ( PubMed , DOI )

  59. Adachi T, Kakuta S, Aihara Y, Kamiya T, Watanabe Y, Osakabe N, Hazato N, Miyawaki A, Yoshikawa S, Usami T, Karasuyama H, Kimoto-Nira H, Hirayama K, Tsuji NM.: Visualization of Probiotic-Mediated Ca2+ Signaling in Intestinal Epithelial Cells In Vivo. Front Immunol.. 2016; 7 (601): ( DOI )

  60. Takahiro Arakawa, Kenta Iitani, Toshiyuki Sato, Koji Toma, Kohji Mitsubayashi: Ethanol vapor imaging system “sniffer camera” for evaluation of alcohol metabolism from breath and palm skin gas Procedia Engineering. 2016; 168 522-528. ( DOI )

  61. Hirokazu Saito, Yuki Hashimoto, Takeshi Minamide, Takuo Kon, Koji Toma, Takahiro Arakawa, and Kohji Mitsubayashi: Fiber optic bio-sniffer (biochemical gas sensor) for gaseous dimethyl sulfide Sensors and Materials. 2016; 28 (12): 1295-1301.

  62. Takahiro Arakawa, Yusuke Kuroki, Hiroki Nitta, Prem Chouhan, Koji Toma, Shin-ichi Sawada, Shuhei Takeuchi, Toshiaki Sekita, Kazunari Akiyoshi, Shunsuke Minakuchi, Kohji Mitsubayashi: Mouthguard biosensor with telemetry system for monitoring of saliva glucose: A novel cavitas sensor Biosensors and Bioelectronics. 2016; 84 106-111.

  63. Po-Jen Chien, Ming Ye, Takuma Suzuki, Koji Toma, Takahiro Arakawa, Yasuhiko Iwasaki, Kohji Mitsubayashi: Optical isopropanol biosensor using NADH-dependent secondary alcohol dehydrogenase (S-ADH) Talanta. 2016; 159 418-424. ( DOI )

  64. Koji Toma, Kumiko Miyajima, Shin-ichi Sawada, Takahiro Arakawa, Hiroyuki Kudo, Kazunari Akiyoshi, Kohji Mitsubayashi: Direct measurement of gaseous formaldehyde from food with a fiber-optic biochemical gas sensor (bio-sniffer) Sensors and Materials. 2016; 28 (12): 1265-1272.

  65. Ohashi N, Harada S, Mizuguchi T, Irahara Y, Yamada Y, Kotani M, Nomura W, Matsushita S, Yoshimura K, Tamamura H: Small Molecular CD4 Mimics Containing Mono-cyclohexyl Moieties as HIV Entry Inhibitors. ChemMedChem a joint special issue with ChemBioChem: Protein–Protein Interactions. 2016; 11 (8): 940-946.

  66. Hiramatsu K, Tamamura H: A Mild Method for the Direct Fluorination of Pyrroles by Using a Lipophilic Anionic Phase-Transfer Catalyst. Eur. J. Org. Chem. 2016; 21 3491-3494.

  67. Toyama K, Mizuguchi T, Nomura W, Tamamura H: Functional Evaluation of Fluorescein-Labeled Derivatives of a Peptide Inhibitor of the EGF Receptor Dimerization Bioorg. Med. Chem. 2016; 24 (16): 3406-3412.

  68. Abduelmula A, Huang R, Pu Q, Tamamura H, Puopolo G. M & Saberi B. B: SDF-1 Controls the Muscle and Blood Vessel Formation of the Somite. Int. J. Dev. Biol. 2016; 60(1-2-3) (29-38):

  69. Isao Kii, Yuto Sumida, Toshiyasu Goto, Rie Sonamoto, Yukiko Okuno, Suguru Yoshida, Tomoe Kato-Sumida, Yuka Koike, Minako Abe, Yosuke Nonaka, Teikichi Ikura, Nobutoshi Ito, Hiroshi Shibuya, Takamitsu Hosoya, Masatoshi Hagiwara: Selective inhibition of the kinase DYRK1A by targeting its folding process. Nat Commun. 2016; 7 11391. ( PubMed , DOI )

  70. Takano H, Narumi T, Nomura W, Tamamura H: Microwave-Assisted Synthesis of Azacoumarin Fluorophores and the Fluorescence Characterization J. Org. Chem. 2016; in press

  71. Nakamura T, Campbell J.R, Moore A.R, Otsu S, Aikawa H, Tamamura H, Mitsuya H: Development and Validation of a Cell-based Assay System to Assess Human Immunodeficiency Virus Type 1 Integrase Multimerization J. Virol. Methods. 2016; 236 196-206.

  72. Nomura W, Mizuguchi T & Tamamura H: Multimerized HIV-gp41-derived Peptides as Fusion Inhibitors and Vaccines Biopolymers: Peptide Science. 2016; 106 (4): 622-628.

  73. Teikichi Ikura, Nobutoshi Ito: Crystal Structure of the Vitamin D Receptor Ligand-Binding Domain with Lithocholic Acids. Vitam. Horm.. 2016; 100 117-136. ( PubMed , DOI )

  1. Kumiko Miyajima, Kon Hiromi, Takahiro Arakawa, Kiyoko Shiba, Kohji Mitsubayashi: Fluoroimmunoassay system for fiber-optic measurement of house dust mite allergen (Der f1) Sensors and Materials. 2015.12; 27 (9): 871-880.

  2. Yuki Suzuki, Ye Ming, Kumiko Miyajima, Takahiro Arakawa, Shin-ichi Sawada, Hiroyuki Kudo, Kazunari Akiyoshi, Kohji Mitsubayashi: A fluorometric biochemical gas sensor (biosniffer) for acetaldehyde vapor based on catalytic reaction of aldehyde dehydrogenase Sensors and Materials. 2015.12; 27 (11): 1123-1130.

  3. Yoshida S, Sugimura Y, Hazama Y, Nishiyama Y, Yano T, Shimizu S, Hosoya T: A mild and facile synthesis of aryl and alkenyl sulfides #Ivia#IR copper-catalyzed deborylthiolation of organoborons with thiosulfonates. Chem Commun. 2015.12; 51 (93): 16613-16616. ( PubMed , DOI )

  4. Yusuke Watarai, Michiyasu Ishizawa, Teikichi Ikura, Flavia C M Zacconi, Shigeyuki Uno, Nobutoshi Ito, Antonio Mouriño, Hiroaki Tokiwa, Makoto Makishima, Sachiko Yamada: Synthesis, Biological Activities, and X-ray Crystal Structural Analysis of 25-Hydroxy-25(or 26)-adamantyl-17-[20(22),23-diynyl]-21-norvitamin D Compounds. J. Med. Chem.. 2015.12; 58 (24): 9510-9521. ( PubMed , DOI )

  5. Koji Toma, Yurika Suzuki, Chisato Kishikawa, Mana Saito, Kumiko Miyajima, Takahiro Arakawa, Hiroji Shimomura, Kohji Mitsubayashi: Chemifluorescent optical fiber immunosensor for on-site bioaerosol monitoring system Sensors and Materials. 2015.12; 27 (11): 1113-1122. ( DOI )

  6. K. Nam, T. Kimura, A. Kishida: Preparation fibrillized collagen-glycosaminoglycan complex matrix using fibrillogenesis Macromolecular Symposia. 2015.12; 358 (1): 95-105. ( DOI )

  7. 張永巍,岩田拓也,南広祐,中村奈緒子,橋本良秀,木村剛,岸田晶夫: 傾斜型脱細胞化生体組織/高分子複合体の調整 Annual Reports of the Institute of Biomaterials and Bioengineering. 2015.12; 49 18-21.

  8. Yu. R.: Miyamura, N.; Okamoto-Uchida, Y.; Arima, N.; Ishigami-Yuasa, M.; Kagechika, H.; Nishina, H.: A Modified Murine Embryonic Stem Cell Test for Evaluating the Teratogenic Effects of Drugs on Early Embryogenesis Plos ONE. 2015.11; 10 e0145286. ( DOI )

  9. J. Negishi, S. Funamoto, T. Kimura, K. Nam, T. Higami, A. Kishida: Porcine radial artery decellularization by high hydrostatic pressure J. Tissue Eng. Regen. Med.. 2015.11; 9 (11): 144-151.

  10. M. Tabuchi，J. Negishi，A. Yamashita，T. Higami，A. Kishida，S. Funamoto: Effect of decellularized tissue powders on a rat model of acute myocardial infarction Mater. Sci. Eng. C-Mater. Biol. Appl.. 2015.11; 56 494-500. ( DOI )

  11. Tatsuro Goda, Daiki Higashi, Akira Matsumoto, Toru Hoshi, Takashi Sawaguchi, Yuji Miyahara: Dual aptamer-immobilized surfaces for improved affinity through multiple target binding in potentiometric thrombin biosensing Biosensors and Bioelectronics. 2015.11; 73 174-180. ( DOI )

  12. Tatsuro Goda, Masahiro Toya, Akira Matsumoto, Yuji Miyahara: Poly(3,4-ethylenedioxythiophene) bearing phosphorylcholine groups for metal-free, antibody-free, and low-impedance biosensors sspecific for C-reactive protein ACS Applied Materials and Interfaces. 2015.11; 7 (49): 27440-27448. ( DOI )

  13. Okamoto M, Hidaka A, Toyama M, Hosoya T, Yamamoto M, Hagiwara M, Baba M: Selective inhibition of HIV-1 replication by the CDK9 inhibitor FIT-039. Antiviral Res. 2015.11; 123 1-4. ( PubMed , DOI )

  14. Yoshida S, Yano T, Misawa Y, Sugimura Y, Igawa K, Shimizu S, Tomooka K, Hosoya T: Direct thioamination of arynes via reaction with sulfilimines and migratory #IN#IR-arylation. J Am Chem Soc. 2015.11; 137 (44): 14071-14074. ( PubMed , DOI )

  15. Niwa T, Ochiai H, Watanabe Y, Hosoya T: Ni/Cu-Catalyzed Defluoroborylation of Fluoroarenes for Diverse C-F Bond Functionalizations. J Am Chem Soc. 2015.11; 137 (45): 14313-14318. ( PubMed , DOI )

  16. Yoshida S, Hosoya T: The Renaissance and Bright Future of Synthetic Aryne Chemistry. Chem Lett. 2015.11; 44 (11): 1450-1460. ( DOI )

  17. Yasuaki Anami, Yuta Sakamaki, Toshimasa Itoh, Yuka Inaba, Makoto Nakabayashi, Teikichi Ikura, Nobutoshi Ito, Keiko Yamamoto: Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activity. Bioorg. Med. Chem.. 2015.11; 23 (22): 7274-7281. ( PubMed , DOI )

  18. Wataru Nomura, Takaaki Mizuguchi & Hirokazu Tamamura: Multimerized HIV-gp41-derived Peptides as Fusion Inhibitors and Vaccines Biopolymers: Peptide Science. 2015.11; ( DOI )

  19. Ming Ye, Po-Jen Chien, Koji Toma, Takahiro Arakawa, Kohji Mitsubayashi: An acetone bio-sniffer (gas phase biosensor) enabling assessment of lipid metabolism from exhaled breath. Biosensors and Bioelectronics. 2015.11; 73 208-213. ( PubMed , DOI )

  20. Manjiri R Kulkarni, Monirul M Islam, Nobutaka Numoto, Montasir Elahi, Mamunur R Mahib, Nobutoshi Ito, Yutaka Kuroda: Structural and biophysical analysis of sero-specific immune responses using epitope grafted Dengue ED3 mutants. Biochim. Biophys. Acta. 2015.10; 1854 (10 Pt A): 1438-1443. ( PubMed , DOI )

  21. Yoshida S, Shimomori K, Nonaka T, Hosoya T: Facile Synthesis of Diverse Multisubstituted #Iortho#IR-Silylaryl Triflates via C–H Borylation. Chem Lett. 2015.10; 44 (10): 1324-1326. ( DOI )

  22. Koji Toma, Daisuke Miki, Chisato Kishikawa, Naoyuki Yoshimura, Kumiko Miyajima, Takahiro Arakawa, Hiromi Yatsuda, Kohji Mitsubayashi: Repetitive immunoassay with a surface acoustic wave device and a highly stable protein monolayer for on-site monitoring of airborne dust mite allergens. Analytical Chemistry. 2015.10; 87 (20): 10470-10474. ( PubMed , DOI )

  23. Yumiko Oishi, Ichiro Manabe: Immunometabolic control of homeostasis and inflammation Inflammation and Regeneration. 2015.09; 35 (4): 185-192.

  24. Tomoko Gessei, Takahiro Arakawa, Hiroyuki Kudo, Kohji Mitsubayashi: A fiber-optic sorbitol biosensor based on NADH fluorescence detection toward rapid diagnosis of diabetic complications Analyst. 2015.09; 140 (18): 6335-6342.

  25. Sonamoto R, Kii I, Koike Y, Sumida Y, Kato-Sumida T, Okuno Y, Hosoya T, Hagiwara M: Identification of a DYRK1A Inhibitor that Induces Degradation of the Target Kinase using Co-chaperone CDC37 fused with Luciferase nanoKAZ. Sci Rep. 2015.08; 5 12728. ( PubMed , DOI )

  26. Hosoya T, Iimori R, Yoshida S, Sumida Y, Sahara-Miura Y, Sato J, Inouye S: Concise Synthesis of #Iv#IR-Coelenterazines. Org Lett. 2015.08; 17 (15): 3888-3891. ( PubMed , DOI )

  27. Masaki S, Kii I, Sumida Y, Kato-Sumida T, Ogawa Y, Ito N, Nakamura M, Sonamoto R, Kataoka N, Hosoya T, Hagiwara M: Design and synthesis of a potent inhibitor of class 1 DYRK kinases as a suppressor of adipogenesis. Bioorg Med Chem. 2015.08; 23 (15): 4434-4441. ( PubMed , DOI )

  28. Morooka S, Hoshina M, Kii I, Okabe T, Kojima H, Inoue N, Okuno Y, Denawa M, Yoshida S, Fukuhara J, Ninomiya K, Ikura T, Furuya T, Nagano T, Noda K, Ishida S, Hosoya T, Ito N, Yoshimura N, Hagiwara M: Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice. Mol Pharmacol. 2015.08; 88 (2): 316-325. ( PubMed , DOI )

  29. P. Wu, N. Nakamura, T. Kimura, K. Nam, T. Fujisato, S. Funamoto, T. Higami, A. Kishida: Decellularized porcine aortic intima-media as a potential cardiovascular biomaterial Interact Cardiovasc Thorac Surg. 2015.08; 21 (2): 189-194. ( DOI )

  30. Y. Hashimoto, S. Funamoto, S. Sasaki, J. Negishi, T. Honda, S. Hattori, K Nam, T. Kimura, M. Mochizuki, H. Kobayashi, A. Kishida: Corneal regeneration by deep anterior lamellar keratoplasty (DALK) using decellularized corneal matrix PLOS ONE. 2015.07; 10 (7): e0131989. ( DOI )

  31. Yoshida S, Hazama Y, Sumida Y, Yano T, Hosoya T: An Alternative Method for Generating Arynes from #Iortho#IR-Silylaryl Triflates: Activation by Cesium Carbonate in the Presence of a Crown Ether. Molecules. 2015.06; 20 (6): 10131-10140. ( PubMed , DOI )

  32. Takuya Kobayakawa, Tetsuo Narumi, Hirokazu Tamamura: Remote Stereoinduction in the Organocuprate-Mediated Allylic Alkylation of Allylic gem-Dichlorides: Highly Diastereoselective Synthesis of (Z)-Chloroalkene Dipeptide Isosteres. Organic Letters. 2015.05; 17 (10): 2302-2305. ( PubMed , DOI )

  33. Yoshida S, Karaki F, Uchida F, Hosoya T: Generation of cycloheptynes and cyclooctynes #Ivia#IR a sulfoxide-magnesium exchange reaction of readily synthesized 2-sulfinylcycloalkenyl triflates. Chem Commun. 2015.05; 51 (42): 8745-8748. ( PubMed , DOI )

  34. Yoshida S, Uchida K, Hosoya T: Generation of Arynes Using Trimethylsilylmethyl Grignard Reagent for Activation of #Iortho#IR-Iodoaryl or #Iortho#IR-Sulfinylaryl Triflates. Chem Lett. 2015.05; 44 (5): 691-693. ( DOI )

  35. Munkhbayar Munkhjargal, Kohdai Hatayama, Yuki Matsuura, Koji Toma, Takahiro Arakawa, Kohji Mitsubayashi: Glucose-driven chemo-mechanical autonomous drug-release system with multi-enzymatic amplification toward feedback control of blood glucose in diabetes Biosensors and Bioelectronics. 2015.05; 67 315-320. ( PubMed , DOI )

  36. Takahiro Arakawa, Kazutaka Kita, Xin Wang, Kumiko Miyajima, Koji Toma, Kohji Mitsubayashi: Chemiluminescent imaging of transpired ethanol from the palm for evaluation of alcohol metabolism. Biosensors and Bioelectronics. 2015.05; 67 570-575. ( PubMed , DOI )

  37. Kim H, Terazono H, Takei H, Yasuda K: Depletion effect on concave microstructure at size-specific target particle collection Japanese Journal of Applied Physics . 2015.05; 54 06FL02. ( DOI )

  38. Odaka M, Kim H, Girauit M, Hattori A, Terazono H, Matsuura K, Yasuda K: Evaluation of Imaging Biomarkers for Identification of Single Cancer Cells in Blood Jpn J Appl Phys. 2015.05; 54 (6S1): 06FN04. ( DOI )

  39. Nomura F, Matsuura K, Hattori A, Odaka M, Sugio Y, Kurotobi H, Terazono H, Yasuda K: Development of impedance/external field potential dual measurement system for evaluation of electrophysiological properties of cells on micro electrodes Japanese Journal of Applied Physics. 2015.05; 54 06FN06. ( DOI )

  40. Takahiro Arakawa, Kenta Iitani, Xin Wang, Takumi Kajiro, Koji Toma, Kazuyoshi Yano, Kohji Mitsubayashi: A sniffer-camera for imaging of ethanol vaporization from wine: the effect of wine glass shape. Analyst. 2015.04; 140 (8): 2881-2886. ( PubMed , DOI )

  41. A. Matsuhashi, K. Nam, T. Kimura, A. Kishida: Fabrication of fibrillized collagen microspheres with microstructure resembling extracellular matrix Soft Matter. 2015.04; 11 (14): 2844-2851. ( DOI )

  42. Sean Porazinski, Huijia Wang, Yoichi Asaoka, Martin Behrndt, Tatsuo Miyamoto, Hitoshi Morita, Shoji Hata, Takashi Sasaki, S.F. Gabby Krens, Yumi Osada, Satoshi Asaka, Akihiro Momoi, Sarah Linton, Joel B. Miesfeld, Brian A. Link, Takeshi Senga, Atahualpa Castillo-Morales, Araxi O. Urrutia, Nobuyoshi Shimizu, Hideaki Nagase, Shinya Matsuura, Stefan Bagby, Hisato Kondoh, Hiroshi Nishina, Carl-Philipp Heisenberg and Makoto Furutani-Seiki: YAP is essential for tissue tension to ensure vertebrate 3D body shape Nature. 2015.04;

  43. Yoshida M, Kataoka N, Miyauchi K, Ohe K, Iida K, Yoshida S, Nojima T, Okuno Y, Onogi H, Usui T, Takeuchi A, Hosoya T, Suzuki T, Hagiwara M: Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia. Proc Natl Acad Sci USA. 2015.03; 112 (9): 2764-2769. ( PubMed , DOI )

  44. Y. Sawa，K. Matsuda，E. Tatsumi，G. Matsumiya，T. Abe，K. Fukunaga，A. Kishida，K. Kokubo，T. Masuzawa，A. Myoui，M. Nishimura，T. Nishimura，T. Nishinaka: Journal of Artificial Organs 2014:the year in review Journal of Artificial Organs. 2015.03; 18 (1): 1-7. ( DOI )

  45. Yuta Mochimaru, Morio Azuma, Natsuki Oshima, Yuta Ichijo, Kazuhiro Satou, Kouhei Matsuda, Yoichi Asaoka, Hiroshi Nishina, Takashi Nakakura, Chihiro Mogi, Koichi Sato, Fumikazu Okajima, Hideaki Tomura: Extracellular acidification activates ovarian cancer G-protein-coupled receptor 1 and GPR4 homologs of zebra fish. Biochem. Biophys. Res. Commun.. 2015.02; 457 (4): 493-499. ( PubMed , DOI )

  46. Koichi Fujisawa, Shuji Terai, Toshihiko Matsumoto, Taro Takami, Naoki Yamamoto, Hiroshi Nishina, Makoto Furutani-Seiki, Isao Sakaida: Evidence for a Role of the Transcriptional Regulator Maid in Tumorigenesis and Aging. PLoS ONE. 2015.02; 10 (6): e0129950. ( PubMed , DOI )

  47. Yoshihide Hashimoto, Sada-atsu Mukai, Shin-ichi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi: Nanogel tectonic porous gel loading biologics, nanocarriers, and cells for advanced scaffold Biomaterials. 2015.01; 37 107-115. ( PubMed , DOI )

  48. Mai Sanjoh, Daisuke Iizuka, Akira Matsumoto, Yuji Miyahara: Boronate Based Metal-Free Platform for Diphosphate-Specific Molecular Recognitions. Org Lett. 2015.01; 17 (3): 588-591. ( PubMed , DOI )

  49. Tatsuro Goda, Kazuhiko Ishihara, Yuji Miyahara: Critical Update on 2-Methacryloyloxyethyl Phosphorylcholine (MPC) Polymer Science Journal of Applied Polymer Science. 2015.01; 132 (16): 41766. ( DOI )

  50. Yamada M, Sato N, Ikeda S, Arai T, Sawabe M, Mori S, Yamada Y, Muramatsu M, Tanaka M.: Association of the chromodomain helicase DNA-binding protein 4 (CHD4) missense variation p.D140E with cancer: potential interaction with smoking. Genes Chromosomes Cancer.. 2015; 54 122-128. ( PubMed )

  51. Kawano, S.; Maruyama, J.; Nagashima, S.; Inami, K.; Qiu, W.; Iwasa, H.; Nakagawa, K.; Ishigami-Yuasa, M.; Kagechika, H.; Nishina, H.; Hata, Y.: A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells The Journal of Biochemistry. 2015; 158 413-420. ( DOI )

  52. Nishizawa D, Kasai S, Hasegawa J, Sato N, Yamada H, Tanioka F, Nagashima M, Katoh R, Satoh Y,Tagami M, Ujike H, Ozaki N, Inada T, Iwata N, Sora I, Iyo M, Yamada M, Kondo N, Won MJ, Naruse N,Uehara-Aoyama K, Itokawa M, Ohi K, Hashimoto R, Tanisawa K, Arai T, Mori S, Sawabe M, Naka-Mieno M, Yamada Y, Yamada M, Sato N, Muramatsu M, Tanaka M, Irukayama-Tomobe Y, Saito YC, SakuraiT, Hayashida M, Sugimura H, Ikeda K: Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val308Ile and nicotine dependence in genome-wide and subsequent association studies. Mol Brain. 2015; 8 50. ( PubMed , DOI )

  53. M. Tabata, H. Yang, F. Mannan, Y. Katayama, T. Goda, A. Matsumoto, A. Seichi, K. Suzuki, Y. Miyahara: ELECTROCHEMICAL REAL-TIME MONITORING OF ISOTHERMAL NUCLEIC ACID AMPLIFICATION FOR QUANTITATIVE ANALYSIS 2015 TRANSDUCERS - 2015 18TH INTERNATIONAL CONFERENCE ON SOLID-STATE SENSORS, ACTUATORS AND MICROSYSTEMS (TRANSDUCERS). 2015; 1553-1556. ( DOI )

  54. Miyuki Tabata, Tatsuro Goda, Akira Matsumoto, Yuji Miyahara: Electrochemical label-free degranulation monitoring for in-situ evaluation of cellular function 2015 37TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC). 2015; 2015-November 3177-3180. ( DOI )

  55. Nomura W, Koseki T, Ohashi N, Mizuguchi T, Tamamura H: Trivalent Lignds for CXCR4 Bearing Polyproline Linkers Show Specific Recognition for Cells with Increased CXCR4 Expression. Org Biomol Chem. 2015; 32 (13): 8734-8739.

  56. Mizuguchi T, Ohashi N, Nomura W, Komoriya M, Hashimoto C, Yamamoto N, Murakami T, Tamamura H: Anti-HIV Screening for Cell-Penetrating Peptides Using Chloroquine and Identification of Anti-HIV Peptides Derived from Matrix Proteins. Bioorg Med Chem. 2015; 15 (23): 4423-4427.

  57. Nomura W, Ohashi N, Mori A, Tamamura H: An In-cell Fluorogenic Tag-probe System for Protein Dynamics Imaging Enabled by Cell-Penetrating Peptides. Bioconjugate Chem. 2015; 6 (26): 1080-1085.

  58. Takano H, Narumi T, Nomura W, Furuta T, Tamamura H: Utilization of the Heavy Atom Effect for the Development of a Photosensitive 8-Azacoumarin-type Photolabile Protecting Group Org Lett. 2015; 21 (17): 5372-5375.

  59. Nomura W, Aikawa H, Taketomi S, Tanabe M, Mizuguchi T, Tamamura H: Exploration of Labeling of Near Infrared Dyes on the Polyproline Linker for Bivalent-Type CXCR4 Ligands Bioorg Med Chem. 2015; 21 (23): 6967-6973.

  1. Goda Tatsuro, Oohashi Mikiya, Matsumoto Akira, Hoshi Toru, Sawaguchi Takashi, Pumera Martin, Miyahara Yuji: Chemical Optimization for Simultaneous Voltammetric Detection of Molybdenum and Silver Nanoparticles in Aqueous Buffer Solutions ChemElectroChem. 2014.12; 1 (12): 2110-2115. ( DOI )

  2. Hidetaka Fujii, Masaharu Shin-Ya, Shigeo Takeda, Yoshihide Hashimoto, Sada-atsu Mukai, Shin-ichi Sawada, Tetsuya Adachi, Kazunari Akiyoshi, Tsuneharu Miki, Osam Mazda: Cycloamylose-nanogel drug delivery system-mediated intratumor silencing of the vascular endothelial growth factor regulates neovascularization in tumor microenvironment Cancer Sci. 2014.12; 105 (12): 1616-1625. ( PubMed , DOI )

  3. Kwangwoo Nam, Rie Matsushima, Tsuyoshi Kimura, Toshiya Fujisato, Akio Kishida: In vivo characterization of a decellularized dermis-polymer complex for use in percutaneous devices. Artif Organs. 2014.12; 38 (12): 1060-1065. ( PubMed , DOI )

  4. Naruse M, Ono R, Irie M, Nakamura K, Furuse T, Hino T, Oda K, Kashimura M, Yamada I, Wakana S, Yokoyama M, Ishino F, Kaneko-Ishino T. : Sirh7/Ldoc1 knockout mice exhibit placental P4 overproduction and delayed parturition. Development. 2014.12; 141 (24): 4763-4771. ( PubMed )

  5. Aki Matsuhashi, Kwangwoo Nam，Tsuyoshi Kimura，Akio Kishida: Fundamental study on controlling preparative condisition of fibrillized collagen microsphere resembling the extracellular matrix mcrostructure Annual Reports of the Institute of Biomaterials and Bioengineering. 2014.12; 48 17-21.

  6. Akira Matsumoto, Yuji Miyahara: Current Development Status and Perspectives of Self-Regulated Insulin Delivery Systems: A Review ELECTRONICS AND COMMUNICATIONS IN JAPAN. 2014.12; 97 (12): 57-61. ( DOI )

  7. Koji Toma, Hiroshi Kano, Andreas Offenhäusser: Label-free measurement of cell-electrode cleft gap distance with high spatial resolution surface plasmon microscopy. ACS Nano. 2014.12; 8 (12): 12612-12619. ( PubMed , DOI )

  8. Jonas Albers, Koji Toma, Andreas Offenhäusser: Engineering connectivity by multiscale micropatterning of individual populations of neurons. Biotechnol J. 2014.12; 10 (2): 332-338. ( PubMed , DOI )

  9. Yoshida S, Uchida K, Igawa K, Tomooka K, Hosoya T: An efficient generation method and remarkable reactivities of 3-triflyloxybenzyne. Chem Commun (Camb.). 2014.11; 50 (95): 15059-15062. ( PubMed , DOI )

  10. Xu F, Peng L, Shinohara K, Morita T, Yoshida S, Hosoya T, Orita A, Otera J: Substituted 5,6,11,12-Tetradehydrodibenzo[a,e]cyclooctenes: Syntheses, Properties, and DFT Studies of Substituted Sondheimer-Wong Diynes. J Org Chem. 2014.11; 79 (23): 11592-11608. ( PubMed , DOI )

  11. Sumida Y, Harada R, Kato-Sumida T, Johmoto K, Uekusa H, Hosoya T: Boron-Selective Biaryl Coupling Approach to Versatile Dibenzoxaborins and Application to Concise Synthesis of Defucogilvocarcin M. Org Lett. 2014.11; 16 (23): 6240-6243. ( PubMed , DOI )

  12. Tatsuro Goda, Peter Kjall, Kazuhiko Ishihara, Agneta Richter-Dahlfors and Yuji Miyahara,: Biomimetic interfaces reveal activation dynamics of C-reactive protein in local microenvironments. Adv Healthc Mater. 2014.11; 3 (11): 1733-1738. ( PubMed , DOI )

  13. Kwangwoo Nam, Ji-Hun Seo, Tsuyoshi Kimura, Nobuhiko Yui, Akio Kishida: Relationships between molecular mobility, fibrillogenesis of collagen molecules, and the inflammatory response: An experimental study in vitro and in vivo Journal of Colloid and Interface Science . 2014.11; 433 16-25. ( DOI )

  14. Kwangwoo Nam, Yukiko shimatsu, Rie Matsushima, Tsuyoshi Kimura, Akio Kishida: In-situ polymerization of PMMA inside decellularized dermis using UV photopolymerization European Polymer Journal. 2014.11; 60 163-171. ( DOI )

  15. Miyuki Tabata, Kozue Nogami, Tatsuro Goda, Akira Matsumoto, Yuji Miyahara: Fabrication of Self-assembled Monolayer/AgCl Mixed Surface and It's Electrochemical Properties IEEJ Transactions on Sensors and Micromachines. 2014.10; 134 (10): 315-319.

  16. Yoshida S, Nonaka T, Morita T, Hosoya T: Modular synthesis of bis- and tris-1,2,3-triazoles by permutable sequential azide-aryne and azide-alkyne cycloadditions. Org Biomol Chem. 2014.10; 12 (38): 7489-7493. ( PubMed , DOI )

  17. Yoshida S, Hatakeyama Y, Johmoto K, Uekusa H, Hosoya T: Transient protection of strained alkynes from click reaction via complexation with copper. J Am Chem Soc. 2014.10; 136 (39): 13590-13593. ( PubMed , DOI )

  18. Ping Li Wu, Tsuyoshi Kimura, Hiroko Tadokoro, Kwangwoo Nam, Toshiya Fujisato, Akio Kishida: Relation between the tissue structure and protein permeability of decellularized porcine aorta. Mater Sci Eng C Mater Biol Appl. 2014.10; 43 465-471. ( PubMed , DOI )

  19. Tsuyoshi Kimura, Akira Okuno, Yuichi Ohya, Akio Kishida: Assembly of poly(vinyl alcohol) and DNA via Hydrogen Bonds Induced by High Hydrostatic Pressurization Sensors and Materials. 2014.10; 26 (8): 607-614. ( DOI )

  20. Jun Negishi, Kwangwoo Nam, Tsuyoshi Kimura, Yoshihide Hashimoto, Seiichi Funamoto, Tetsuya Higami, Toshiya Fujisato, Akio Kishida: Fabrication of a heparin-PVA complex hydrogel for application as a vascular access. J Biomed Mater Res B Appl Biomater. 2014.10; 102 (7): 1426-1433. ( PubMed , DOI )

  21. Kwangwoo Nam, Takuya Iwata, Tsuyoshi Kimura, Hiroki Ikake, Shigeru Shimizu, Toru Masuzawa, Akio Kishida: Adhesion Between Polymer Surface Modified by Graft Polymerization and Tissue During Surgery Using an Ultrasonically Activated Scalpel Device Journal of Applied Polymer Science . 2014.10; 131 (20): ( DOI )

  22. Bo Yao, Yichen Liu, Miyuki Tabata, Huangtianzhi Zhu and Yuji Miyahara: Sensitive detection of microRNA by chronocoulometry and rolling circle amplification on a gold electrode. Chem Commun . 2014.09; 50 (68): 9704-9706. ( PubMed , DOI )

  23. Jun Negishi, Yoshihide Hashimoto, Kwangwoo Nam, Tsuyoshi Kimura, Seiichi Funamoto, Akio Kishida: Application of a vacuum pressure impregnation technique for rehydrating decellularized tissues. Tissue Eng Part C Methods. 2014.09; 20 (9): 724-730. ( PubMed , DOI )

  24. Kim H, Terazono H, Takei H, Yasuda K: Cup-Shaped Superparamagnetic Hemispheres for Size-Selective Cell Filtration Sci. Rep. 2014.09; 4 6362. ( DOI )

  25. Nobuyuki Shimizu, Shizuka Ishitani, Atsushi Sato, Hiroshi Shibuya, Tohru Ishitani: Hipk2 and PP1c cooperate to maintain Dvl protein levels required for Wnt signal transduction. Cell Rep. 2014.09; 8 (5): 1391-1404. ( PubMed , DOI )

  26. Marie Shimada, Masaaki Ozawa, Kojiro Iwamoto, Yoshiyasu Fukuyama, Akio Kishida, Ayumi Ohsaki: A Lanostane Triterpenoid and Three Cholestane Sterols from Tilia kiusiana Chemical and Pharmaceutical Bulletin . 2014.09; 62 (9): 937-941. ( DOI )

  27. Inouye S, Sato J-i, Sahara-Miura Y, Hosoya T, Suzuki T: Unconventional secretion of the mutated 19 kDa protein of Oplophorus luciferase (nanoKAZ) in mammalian cells. Biochem Biophys Res Commun. 2014.08; 450 (4): 1313-1319. ( PubMed , DOI )

  28. Yamamoto M, Onogi H, Kii I, Yoshida S, Iida K, Sakai H, Abe M, Tsubota T, Ito N, Hosoya T, Hagiwara M: CDK9 inhibitor FIT-039 prevents replication of multiple DNA viruses. J Clin Invest. 2014.08; 124 (8): 3479-3488. ( PubMed , DOI )

  29. Akira Matsumoto, Kazunori Kataoka, Yuji Miyahara: New directions in the design of phenylboronate-functionalized polymers for diagnostic and therapeutic applications POLYMER JOURNAL. 2014.08; 46 (8): 483-491. ( DOI )

  30. Kim H, Terazono H, Nakamura Y, Sakai K, Hattori A, Odaka M, Mathias George Girault, Arao T, Nishio K, Miyagi Y, Yasuda K: Development of On-Chip Multi-Imaging Flow Cytometry for Identification of Imaging Biomarkers of Clustered Circulating Tumor Cells PLoS One. 2014.08; 9 e104372. ( DOI )

  31. Martin Bauch, Koji Toma, Mana Toma, Qingwen Zhang, Jakub Dostalek: Plasmon-Enhanced Fluorescence Biosensors: a Review PLASMONICS. 2014.08; 9 (4): 781-799. ( DOI )

  32. Dechamethakun S, Ikeda S, Arai T, Sato N, Sawabe M, Muramatsu M. : Associations between the CDKN2A/B, ADTRP and PDGFD Polymorphisms and the Development of Coronary Atherosclerosis in Japanese Patients. J. Atheroscler. Thromb.. 2014.07; 21 (7): 680-690. ( PubMed )

  33. Erna G. Santoso, Keita Yoshida, Yasushi Hirota, Masanori Aizawa, Osamu Yoshino, Akio Kishida, Yutaka Osuga, Shigeru Saito, Takashi Ushida, Katsuko S.Furukawa: Application of Detergents or High Hydrostatic Pressure as Decellularization Processes in Uterine Tissues and Their Subsequent Effects on In Vivo Uterine Regeneration in Murine Models PLOS ONE. 2014.07; 9 (7): e103201. ( DOI )

  34. Suzuki M, Doi H, Koyama H, Zhang Z, Hosoya T, Onoe H, Watanabe Y: Pd0-mediated rapid cross-coupling reactions, the rapid C-[11C]methylations, revolutionarily advancing the syntheses of short-lived PET molecular probes. Chem Rec. 2014.06; 14 (3): 516-541. ( PubMed , DOI )

  35. Kumiko Miyajima, Yurika Suzuki, Daisuke Miki, Moeka Arai, Takahiro Arakawa, Hiroji Shimomura, Kiyoko Shiba, Kohji Mitsubayashi: Direct analysis of airborne mite allergen (Der f1) in the residential atmosphere by chemifluorescent immunoassay using bioaerosol sampler. Talanta. 2014.06; 123 241-246. ( PubMed , DOI )

  36. Shuji Terai, Taro Takami, Naoki Yamamoto, Koichi Fujisawa, Tsuyoshi Ishikawa, Yohei Urata, Haruko Tanimoto, Takuya Iwamoto, Yuko Mizunaga, Takashi Matsuda, Takashi Oono, Miho Marumoto, Guzel Burganova, Luiz Fernando Quintanilha, Isao Hidaka, Yoshio Marumoto, Issei Saeki, Koichi Uchida, Takahiro Yamasaki, Kenji Tani, Yasuho Taura, Yasuhiko Fujii, Hiroshi Nishina, Kiwamu Okita, Isao Sakaida: Status and prospects of liver cirrhosis treatment by using bone marrow-derived cells and mesenchymal cells. Tissue Eng Part B Rev. 2014.06; 20 (3): 206-210. ( PubMed , DOI )

  37. Yoshida S, Misawa Y, Hosoya T: Formal C–H-Azidation Based Shortcut to Diazido Building Blocks for the Versatile Preparation of Photoaffinity Labeling Probes. Eur J Org Chem. 2014.05; (19): 3991-3995. ( DOI )

  38. Hattori A, Kim H, Terazono H, Odaka M, Girault M, Yasuda K : Identification of Cells using Morphological Information of Bright Field/Fluorescent Milti-imaging Flow Cytometer Images Jpn J Appl Phys. 2014.05; 53 06JL03. ( DOI )

  39. Kim H, Terazono H, Takei H, Yasuda K: Fabrication of multilayered superparamagnetic particles based on sequential thermal deposition method Jpn J Appl Phys. 2014.05; 53 06JJ01. ( DOI )

  40. Satoru Nishino, Akio Kishida, Hidekazu Yoshizawa, Koichiro Shiomori: A Protein Extraction System with Water/Oil Microemulsion formed by a Biodegradable Polymer Surfactant Solvent Extraction Research and Development, Japan . 2014.05; 21 (1): 47-54. ( DOI )

  41. Gessei T, Arakawa T, Kudo H, Saito H, Mitsubayashi K: Amperometric Biosensor based on Enzyme Immobilization with Post Process for Medical and Multiple Applications Analytical Letters. 2014.05; 47 1361-1374.

  42. Zeyu Yang, Kentaro Nakagawa, Aradhan Sarkar, Junichi Maruyama, Hiroaki Iwasa, Yijun Bao, Mari Ishigami-Yuasa, Shigeru Ito, Hiroyuki Kagechika, Shoji Hata, Hiroshi Nishina, Shinya Abe, Masanobu Kitagawa, Yutaka Hata: Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model. Mol. Cell. Biol.. 2014.05; 34 (9): 1607-1621. ( PubMed , DOI )

  43. Kudo Takeru, Ishizawa Michiyasu, Maekawa Kazuki, Nakabayashi Makoto, Watarai Yusuke, Uchida Hikaru, Tokiwa Hiroaki, Ikura Teikichi, Ito Nobutoshi, Makishima Makoto, Yamada Sachiko: Combination of triple bond and adamantane ring on the vitamin D side chain produced partial agonists for vitamin D receptor. J Med Chem. 2014.05; 57 (10): 4073-4087. ( PubMed , DOI )

  44. Kim H, Terazono H, Takei H, Yasuda K: DNA Hybridization Efficiency on Concave Surface Nano-Structure in Hemispherical Janus Nanocups Langmuir. 2014.04; 30 (5): 1272-1280. ( DOI )

  45. Keita Nakanaga, Kotaro Hama, Kuniyuki Kano, Takanao Sato, Hiroshi Yukiura, Asuka Inoue, Daisuke Saigusa, Hidetoshi Tokuyama, Yoshihisa Tomioka, Hiroshi Nishina, Atsuo Kawahara, Junken Aoki: Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo. J. Biochem.. 2014.04; 155 (4): 235-241. ( PubMed , DOI )

  46. Terazono H, Matsuura K, Kim H, Takei H, Hattori A, Nomura F, Yasuda K: Homogenous measurement during a circulation-water-based ultrahigh-speed polymerase chain reaction and melting curve analysis device Jpn J Appl Phys. 2014.04; 53 06JM08 . ( DOI )

  47. Y.Sawa, E.Tatsumi, T.Tsukiya, K.Matsuda, K.Fukunaga, A.Kishida, T.Masuzawa, G.Matsumiya, A.Myoui, M.Nishimura, T.Nishimura, T.Nishinaka, E.Okamoto, S.Tokunaga, T.Tomo, Y.Yagi, T.Yamaoka: Journal of Artificial Organs 2013:the year in review Journal of Artificial Organs. 2014.03; 17 (1): 1-8.

  48. Yuki Nagaoka, Hiroshi Yamada, Tsuyoshi Kimura, Akio Kishida, Toshiya Fujisato, Kazuo Takakuda: Reconstruction of small diameter arteries using decellularized vascular scaffolds. J Med Dent Sci. 2014.03; 61 (1): 33-40. ( PubMed )

  49. Takahashi K, Hosoya T, Onoe K, Doi H, Nagata H, Hiramatsu T, Li XL, Watanabe Y, Wada Y, Takashima T, Suzuki M, Onoe H, Watanabe Y: 11C-Cetrozole: An Improved C-11C-Methylated PET Probe for Aromatase Imaging in the Brain. J Nucl Med. 2014.03; 55 (5): 852-857. ( PubMed , DOI )

  50. Saito H, Goto T, Miyajima K, Munkhjargal M, Arakawa T, Mitsubayashi K: Odourless Watermark (Digital Chemocode) System with Biochemical Sniff Scanner Sensors and Materials. 2014.03; 26 109-119.

  51. Saito H, Suzuki Y, Gessei T, Miyajima K, Arakawa T, Mitsubayashi K: Bioelectronic Sniffer (Biosniffer) Based on Enzyme Inhibition of Butyrylcholinesterase for Toluene Detection Sensors and Materials. 2014.03; 26 121-129.

  52. Rie Matsushima, Kwangwoo Nam, Yukiko Shimatsu, Tsuyoshi Kimura, Toshiya Fujisato, Akio Kishida: Decellularized dermis-polymer complex provides a platform for soft-to-hard tissue interfaces. Materials Science & Engineering. C, Materials for Biological Applications. 2014.02; 35 354-362. ( PubMed , DOI )

  53. Sumi K, Inoue Y, Nishio M, Naito Y, Hosoya T, Suzuki M, Hidaka H: IOP-lowering effect of isoquinoline-5-sulfonamide compounds in ocular normotensive monkeys. Bioorg Med Chem Lett. 2014.02; 24 (3): 831-834. ( PubMed , DOI )

  54. Inouye S, Sato J, Sahara-Miura Y, Yoshida S, Hosoya T: Luminescence enhancement of the catalytic 19kDa protein (KAZ) of Oplophorus luciferase by three amino acid substitutions. Biochem Biophys Res Commun. 2014.02; 445 (1): 157-162. ( PubMed , DOI )

  55. Naoko Nakamura, Kiriko Sugano, Kwangwoo Nam, Tsuyoshi Kimura, Toshiya Fujisato, Akio Kishida: A Basic Study of Osteogenesis between Decellularized Cortical Bone Pieces for Bone Graft Construction Advanced Biomedical Engineering. 2014.01; 2 95-100. ( DOI )

  56. Tadanori Shimomura, Norio Miyamura, Shoji Hata, Ryota Miura, Jun Hirayama, Hiroshi Nishina: The PDZ-binding motif of Yes-associated protein is required for its co-activation of TEAD-mediated CTGF transcription and oncogenic cell transforming activity. Biochem. Biophys. Res. Commun.. 2014.01; 443 (3): 917-923. ( PubMed , DOI )

  57. Tsuyoshi KIMURA,Yukie KANDA,Asami SANO,Kwangwoo NAM,Yoshihiro SASAKI,Kazunari AKIYOSHI,Toshiya FUJISATO,Akio KISHIDA: High Hydrostatic Pressurized Lipoplex Enhances Transfection Efficiency In Vitro Advanced Biomedical Engineering. 2014.01; 2 80-83. ( DOI )

  58. Kaneko T, Nomura F, Hamada T, Abe Y, Takamori H, Sakakura T, Takasuna K, Sanbuissho A, Hyllner J, Sartipy P, Yasuda K.: On-chip in vitro cell-network pre-clinical cardiac toxicity using spatiotemporal human cardiomyocyte measurement on a chip Sci. Rep. 2014.01; 4 4670. ( DOI )

  59. Akira Matsumoto, Yusuke Tsurui, Hiroko Matsumoto, Yasuhiro Maeda, Toru Hoshi, Takashi Sawaguchi, and Yuji Miyahara: Chemo-electrical Signal Transduction by using Stimuli-responsive Polymer Gate-Modified Field Effect Transistor. Chemosensors. 2014; 2 (2): 97-107. ( DOI )

  60. Nami Ohashi, Wataru Nomura, Natsuki Minato & Hirokazu Tamamura : Screening for Protein Kinase C Ligands Using Fluorescence Resonance Energy Transfer. Chem. Pharm. Bull., . 2014; 62 (10): 1019-1025.

  61. Htun NC, Miyaki K, Zhao C, Muramatsu M, Sato N: Epistasis effects of COMT and MTHFR on inter-individual differences in mental health: under the inverted U-shaped prefrontal dopamine model. Biochem Biophys Res Commun.. 2014; 451 (4): 574-579. ( PubMed )

  62. Parlayan C, Ikeda S, Sato N, Sawabe M, Muramatsu M, Arai T: Association analysis of single nucleotide polymorphisms in miR-146a and miR-196a2 on the prevalence of cancer in elderly Japanese: a case-control study. Asian Pac. J. Cancer Prev.. 2014; 15 (5): 2101-2107. ( PubMed )

  63. Zhao C, Ikeda S, Arai T, Naka-Mieno M, Sato N, Muramatsu M, Sawabe M.: Association of the RYR3 gene polymorphisms with atherosclerosis in elderly Japanese population. BMC Cardiovasc Disord. 2014; 14 6. ( PubMed , DOI )

  64. Sato N, Htun NC, Daimon M, Tamiya G, Kato T, Kubota I, Ueno Y, Yamashita H,Fukao A, Kayama T, Muramatsu M. : Likelihood ratio-based integrated personal risk assessment of type 2 diabetes. Endocr. J.. 2014; 61 (10): 967-988. ( PubMed )

  65. Mai Sanjoh, Yuji Miyahara, Kazunori Kataoka, Akira Matsumoto: Phenylboronic acids-based Diagnostic and Therapeutic Applications. Analytical Sciences. 2014; 30 (1): 111-117. ( PubMed )

  66. Yokota M, Kobayashi Y, Morita J, Suzuki H, Hashimoto Y, Sasaki Y, Akiyoshi K, Moriyama K: Therapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis. PLoS ONE. 2014; 9 (7): e101693. ( PubMed , DOI )

  67. Yoshida S, Uchida K, Hosoya T: Generation of arynes triggered by sulfoxide-metal exchange reaction of ortho-sulfinylaryl triflates. Chem Lett. 2014; 43 (1): 116-118. ( DOI )

  68. Tetsuo Narumi, Hikaru Takano, Nami Ohashi, Akinobu Suzuki, Toshiaki Furuta & Hirokazu Tamamura: Isostere-Based Design of 8-Azacoumarin-type Photolabile Protecting Groups: A Hydrophilicity Increasing Strategy for Coumarin-4-ylmethyls. Org. Lett.,. 2014; 16 (4): 1184-1187.

  69. Jun Yamamoto, Masaya Denda, Nami Maeda, Miku Kita, Chiaki Komiya, Tomohiro Tanaka, Wataru Nomura, Hirokazu Tamamura, Youichi Sato, Aiko Yamauchi, Akira Shigenaga & Akira Otaka: Development of a Traceable Linker Containing a Thiol-responsive Amino Acid for the Enrichment and Selective Labelling of Target Proteins. Org. Biomol. Chem.,. 2014; 12 (23): 3821-3826.

  70. Hikaru Takano, Tetsuo Narumi, Nami Ohashi, Akinobu Suzuki, Toshiaki Furuta, Wataru Nomura & Hirokazu Tamamura: Development of the 8-Aza-3-bromo-7-hydroxycoumarin-4-ylmethyl Group as a New Entry of Photolabile Protecting Groups. Tetrahedron, . 2014; 70 (29): 4400-4404.

  71. Jun Yamamoto, Nami Maeda, Chiaki Komiya, Tomohiro Tanaka, Masaya Denda, Koji Ebisuno, Wataru Nomura, Hirokazu Tamamura, Youichi Sato, Aiko Yamauchi, Akira Shigenaga & Akira Otaka: Development of a Fluoride-responsive Amide Bond Cleavage Device that is Potentially Applicable to a Traceable Linker. Tetrahedron,. 2014; 70 (34): 5122-5127.

  72. Yoichi Asaoka, Shoji Hata, Misako Namae, Makoto Furutani-Seiki, Hiroshi Nishina: The Hippo pathway controls a switch between retinal progenitor cell proliferation and photoreceptor cell differentiation in zebrafish. PLoS ONE. 2014; 9 (5): e97365. ( PubMed , DOI )

  1. Toshiyasu Goto, Atsushi Sato, Shungo Adachi, Shun-ichiro Iemura, Tohru Natsume, Hiroshi Shibuya: IQGAP1 protein regulates nuclear localization of β-catenin via importin-β5 protein in Wnt signaling. J. Biol. Chem.. 2013.12; 288 (51): 36351-36360. ( PubMed , DOI )

  2. Matsumoto Akira, Miyahara Yuji: Current and emerging challenges of field effect transistor based bio-sensing. Nanoscale. 2013.11; 5 (22): 10702-10718. ( PubMed , DOI )

  3. Tanaka K, Nakamoto Y, Siwu ER, Pradipta AR, Morimoto K, Fujiwara T, Yoshida S, Hosoya T, Tamura Y, Hirai G, Sodeoka M, Fukase K: Development of bis-unsaturated ester aldehydes as amino-glue probes: sequential double azaelectrocyclization as a promising strategy for bioconjugation. Org Biomol Chem. 2013.11; 11 (42): 7326-7333. ( PubMed , DOI )

  4. Kwangwoo Nam,Kenji Yamamoto,Kosuke Kasahara,Tsuyoshi Kimura,Seiicihi Funamoto,Shigeru Shimizu,Tetsuya Higami,Toru Masuzawa,Akio Kishida: Fundamental study on the development of a surgical device for polymer-tissue adhesion using vibration damping of polymeric materials Journal of Applied Polymer Science . 2013.11; 130 (4): 2532-2537. ( DOI )

  5. Kengia JT, Ko KC, Ikeda S, Hiraishi A, Mieno-Naka M, Arai T, Sato N, Muramatsu M, Sawabe M: A gene variant in the Atp10d gene associates with atherosclerotic indices in Japanese elderly population. Atherosclerosis. 2013.11; 231 (1): 158-62. ( PubMed , DOI )

  6. Goda Tatsuro, Tabata Miyuki, Sanjoh Mai, Uchimura Mai, Iwasaki Yasuhiko, Miyahara Yuji: Thiolated 2-methacryloyloxyethyl phosphorylcholine for an antifouling biosensor platform. Chem Commun (Camb). 2013.10; 49 (77): 8683-8685. ( PubMed , DOI )

  7. Miyajima M, Kusuhara H, Takahashi K, Takashima T, Hosoya T, Watanabe Y, Sugiyama Y: Investigation of the effect of active efflux at the blood-brain barrier on the distribution of nonsteroidal aromatase inhibitors in the central nervous system. J Pharm Sci. 2013.09; 102 (9): 3309-3319. ( PubMed , DOI )

  8. Ikura Teikichi, Ito Nobutoshi: Peptidyl-prolyl isomerase activity of FK506 binding protein 12 prevents tau peptide from aggregating. Protein Eng Des Sel. 2013.09; 26 (9): 539-546. ( PubMed , DOI )

  9. Nakabayashi Makoto, Tsukahara Yoshito, Iwasaki-Miyamoto Yukiko, Mihori-Shimazaki Mika, Yamada Sachiko, Inaba Satomi, Oda Masayuki, Shimizu Masato, Makishima Makoto, Tokiwa Hiroaki, Ikura Teikichi, Ito Nobutoshi: Crystal structures of hereditary vitamin D-resistant rickets-associated vitamin D receptor mutants R270L and W282R bound to 1,25-dihydroxyvitamin D3 and synthetic ligands. J Med Chem. 2013.09; 56 (17): 6745-6760. ( PubMed , DOI )

  10. Higo K, Ikura T, Oda M, Morii H, Takahashi J, Abe R, Ito N: High resolution crystal structure of the Grb2 SH2 domain with a phosphopeptide derived from CD28 PLoS One. 2013.08; 8 (9): e74482. ( DOI )

  11. Masuno Hiroyuki, Ikura Teikichi, Morizono Daisuke, Orita Isamu, Yamada Sachiko, Shimizu Masato, Ito Nobutoshi: Crystal structures of complexes of vitamin D receptor ligand-binding domain with lithocholic acid derivatives. J Lipid Res. 2013.08; 54 (8): 2206-2213. ( PubMed , DOI )

  12. Goda Tatsuro, Miyahara Yuji: Label-free and reagent-less protein biosensing using aptamer-modified extended-gate field-effect transistors. Biosens Bioelectron. 2013.07; 45 89-94. ( PubMed , DOI )

  13. Yasuda K: On-Chip Cellomics: Single-Cell-Based Constructive Cell-Network Assay for Quasi-In Vivo Screening of Cardiotoxicity Proceedings of 35th Annual International Conference of IEEE EMBS. 2013.07; 2825-2828. ( DOI )

  14. Inouye S, Sato J, Sahara-Miura Y, Yoshida S, Kurakata H, Hosoya T: C6-Deoxy coelenterazine analogues as an efficient substrate for glow luminescence reaction of nanoKAZ: the mutated catalytic 19 kDa component of Oplophorus luciferase. Biochem Biophys Res Commun. 2013.07; 437 (1): 23-28. ( PubMed , DOI )

  15. Yoichi Asaoka, Shuji Terai, Isao Sakaida, Hiroshi Nishina: The expanding role of fish models in understanding non-alcoholic fatty liver disease. Dis Model Mech. 2013.07; 6 (4): 905-914. ( PubMed , DOI )

  16. Menno J Oudhoff, Spencer A Freeman, Amber L Couzens, Frann Antignano, Ekaterina Kuznetsova, Paul H Min, Jeffrey P Northrop, Bernhard Lehnertz, Dalia Barsyte-Lovejoy, Masoud Vedadi, Cheryl H Arrowsmith, Hiroshi Nishina, Michael R Gold, Fabio M V Rossi, Anne-Claude Gingras, Colby Zaph: Control of the hippo pathway by Set7-dependent methylation of Yap. Dev. Cell. 2013.07; 26 (2): 188-194. ( PubMed , DOI )

  17. Nobusuke Katoh,Akira T.Kawaguchi,Akio Kishida,Tetsuji Yamaoka: Static Cardiomyoplastly With Synthetic Elastic Net Suppuresses Ventricular Dilatation and Dysfunction After Myocardial Infarction in the Rat: A Chronic Study Artificial Organs. 2013.07; 37 (7): 593-599. ( DOI )

  18. Miduo Xu, Rong Hou, Aya Sato-Hayashizaki, Rongyong Man, Chenghua Zhu, Chisato Wakabayashi, Sachiko Hirose, Takahiro Adachi, Takeshi Tsubata: #ICd72#IR#Uc#UR Is a Modifier Gene that Regulates #IFas#IR#Ulpr#UR-Induced Autoimmune Disease The Journal of Immunology. 2013.06; 190 (11): 5436-5445. ( DOI )

  19. Sumida Y, Kato T, Hosoya T: Generation of arynes via ate complexes of arylboronic esters with an ortho-leaving group. Org Lett. 2013.06; 15 (11): 2806-2809. ( PubMed , DOI )

  20. Masahiro Shimizu, Toshiyasu Goto, Atsushi Sato, Hiroshi Shibuya: WNK4 is an essential effector of anterior formation in FGF signaling. Genes Cells. 2013.06; 18 (6): 442-449. ( PubMed , DOI )

  21. Norie Arima, Yoshimi Uchida, Ruoxing Yu, Koh Nakayama, Hiroshi Nishina: Acetylcholine receptors regulate gene expression that is essential for primitive streak formation in murine embryoid bodies. Biochem. Biophys. Res. Commun.. 2013.06; 435 (3): 447-453. ( PubMed , DOI )

  22. Koichi Okamoto, Brian Lin, Keisuke Imazu, Akihito Yoshida, Koji Toma, Mana Toma, Kaoru Tamada: Tuning Colors of Silver Nanoparticle Sheets by Multilayered Crystalline Structures on Metal Substrates Plasmonics. 2013.06; 8 (2): 581-590. ( DOI )

  23. Terazono H, Hattori A, Kim H, Takei H, Nomura F, Kaneko T, Yasuda K: Temperature-Shift Speed Dependence of Nonspecific Amplification of Polymerase Chain Reaction Examined by 1480nm Photothermal Transition Speed Controllable High-Speed Polymerase Chain Reaction System Jpn J Appl Phys. 2013.06; 52 06GK02. ( DOI )

  24. Kaneko T, Takizawa E, Nomura F, Hamada T, Hattori A, Yasuda K: On-Chip Single-Cell-Shape Control Technology for Understanding Contractile Motion of Cardiomyocytes Measured Using Optical Image Analysis System Jpn J Appl Phys. 2013.06; 52 06GK06 . ( DOI )

  25. Hamada H, Kaneko T, Nomura H, Yasuda K: Physiological Sample Uniformity and Time–Course Stability in Lined-Up Structure of Human Cardiomyocyte Network for In vitro Predictive Drug-Induced Cardiotoxicity Jpn J Appl Phys. 2013.06; 52 06GK05. ( DOI )

  26. Nomura F, Kaneko T, Hamada T, Hattori A, Yasuda K: Advanced Ring-Shaped Microelectrode Assay Combined with Small Rectangular Electrode for Quasi-In vivo Measurement of Cell-to-Cell Conductance in Cardiomyocyte Network Jpn J Appl Phys. 2013.06; 52 06GK07. ( DOI )

  27. Harumiya Satoru, Yoshino Aya, Hayashizaki Koji, Mizuno Kazuya, Yakura Hidetaka, Adachi Takahiro: A system for reconstructing B cell antigen receptor signaling in the mouse myeloma J558L cell line. Arch Biochem Biophys. 2013.05; 533 (1-2): 18-24. ( PubMed , DOI )

  28. Okamoto H, Aizawa H: Fear and anxiety regulation by conserved affective circuits. Neuron. 2013.05; 78 (3): 411-413.

  29. Koji Toma, Emiliano Descrovi, Mana Toma, Mirko Ballarini, Pietro Mandracci, Fabrizio Giorgis, Anca Mateescu, Ulrich Jonas, Wolfgang Knoll, Jakub Dostálek: Bloch surface wave-enhanced fluorescence biosensor Biosensensors and Bioelectronics. 2013.05; 43 108-114. ( PubMed , DOI )

  30. Miyajima K, Miki D, Arakawa T, Kudo H, Saito H, Mitsubayashi K: Fiber-optic Fluoroimmunoassay for Determination of Dermatophagoides farinae Allergen by Flow Analysis Technique. Sensors and Materials. 2013.04; 25 (9): 591-599.

  31. Miyajima K, Koshida T, Arakawa T, Kudo H, Saito H, Yano K, Mitsubayashi K: Fiber-optic fluoroimmunoassay system with a flow-through cell for rapid on-site determination of escherichia coli O157:H7 by monitoring fluorescence dynamics. Biosensors. 2013.04; 3 120-131.

  32. Kudo H, Yamashita T, Miyajima K, Arakawa T, Mitsubayashi K: NADH-fluorometric biochemical gas sensor (bio-sniffer) for evaluation of indoor air quality. IEEE Sensors Journal. 2013.04; 13 (8): 2828-2833.

  33. Arakawa T, Ando E, Wang X, Miyajima K, Takeuchi S, Kudo H, Saito H, Takahashi M, Mitani T, Mitsubayashi K: Chemiluminescent visualization for evaluation of gaseous ethanol distribution during 'La France' pear maturation. IEEE Sensors Journal. 2013.04; 13 (8): 2842-2848.

  34. Arakawa T, Wang X, Kajiro K, Miyajima K, Takeuchi S, Kudo H, Yano K, Mitsubayashi K: A direct gaseous ethanol imaging system for analysis of alcohol metabolism from exhaled breath. Sensors and Actuators B: Chemical. 2013.04; 186 27-33.

  35. Murakami N, Wakabayashi N, Matsushima R, Kishida A, Igarashi Y: Effect of high-pressure polymerization on mechanical properties of PMMA denture base resin. J Mech Behav Biomed Mater. 2013.04; 20 98-104. ( PubMed , DOI )

  36. Munkhjargal M, Matsuura Y, Hatayama K, Miyajima K, Arakawa T, Kudo H, Mitsubayashi K: Glucose-sensing and glucose-driven organic engine with co-immobilized enzyme membrane toward autonomous drug release systems for diabetes. Sensors and Actuators B: Chemical. 2013.04; 188 831-836.

  37. Ji-HunSeo,Sachiro Kakinoki,Yuuki Inoue,kwangoo Nam,Tetsiko Yamaoka,Kazuhiko Ishihara,Akio Kishida,Nobuhiko Yui: The significance of hydrated surface molecular mobility in the control of the morphology of adhering fibroblasts Biomaterials. 2013.04; 34 (13): 3206-3214. ( DOI )

  38. Koji Toma, Milan Vala, Pavel Adam, Jiří Homola, Wolfgang Knoll, Jakub Dostálek: Compact surface plasmon-enhanced fluorescence biochip Optics Express. 2013.04; 21 (8): 10121-10132. ( PubMed )

  39. Brunell C.A, Jokinen V, Sakha P, Terazono H, Nomura F, Kaneko T, Lauri S.E, Franssila S, Rivera C, Yasuda K, Huttunen H.J: Microtechnologies to fuel neurobiological research with nanometer precision Journal of Nanobiotechnology. 2013.04; 11 11. ( DOI )

  40. Y.Sawa、E.Tatsumi、T.Tsukiya、K.Matsuda、K.Fukunaga、A.Kishida、T.Masuzawa、G.Matsumiya、A.Myoui、M.Nishimura、T.Nishimura、T.Nishinaka、E.Okamoto: Journal of Artificial Organs 2012:the year in review J. Artif Organs. 2013.03; 15 (1): 1-8.

  41. Inouye S, Sahara-Miura Y, Sato J, Iimori R, Yoshida S, Hosoya T: Expression, purification and luminescence properties of coelenterazine-utilizing luciferases from Renilla, Oplophorus and Gaussia: comparison of substrate specificity for C2-modified coelenterazines. Protein Expr Purif. 2013.03; 88 (1): 150-156. ( PubMed , DOI )

  42. Yuya Hanazono, Kazuki Takeda, Toshihiko Oka, Tetsuya Abe, Taichi Tomonari, Nobuhiko Akiyama, Yoshiki Aikawa, Masafumi Yohda, Kunio Miki: Nonequivalence observed for the 16-meric structure of a small heat shock protein, SpHsp16.0, from Schizosaccharomyces pombe. Structure. 2013.02; 21 (2): 220-228. ( PubMed , DOI )

  43. Hamada H, Nomura F, Kaneko T, Yasuda K, Okamoto M: Exploring the implicit interlayer regulatory mechanism between cells and tissue: Stochastic mathematical analyses of the spontaneous ordering in beating synchronization BioSystems. 2013.02; 111 208-215. ( DOI )

  44. Tetsuo Narumi, Haruo Aikawa, Tomohiro Tanaka, Chie Hashimoto, Nami Ohashi, Wataru Nomura, Takuya Kobayakawa, Hikaru Takano, Yuki Hirota, Tsutomu Murakami, Naoki Yamamoto, Hirokazu Tamamura: Low-molecular-weight CXCR4 ligands with variable spacers. ChemMedChem. 2013.01; 8 (1): 118-124. ( PubMed , DOI )

  45. Nami Ohashi, Wataru Nomura, Tetsuo Narumi & Hirokazu Tamamura: Peptide-based Ligand Screening and Functional Analysis of Protein Kinase C Biopolymers. 2013; 100 (6): 613-620.

  46. Akira Matsumoto, Takehiko Ishii, Kazunori Kataoka, Yuji Miyahara: Glucose-Responsive Gel for Self-Regulated Insulin Delivery System. Drug Delivery System. 2013; 28 (2): 119-126. ( DOI )

  47. Stephanie Deshayes, Horacio Cabral, Takehiko Ishii, Yutaka Miura, Shutaro Kobayashi, Takashi Yamashita, Akira Matsumoto, Yuji Miyahara, Nobuhiro Nishiyama and Kazunori Kataoka: Phenylboronic acid-installed polymeric micelles for targeting sialylated epitopes in solid tumors. J. Am. Chem. Soc.. 2013; 135 (41): 15501-15507. ( DOI )

  48. Akira Matsumoto, Hiroko Matsumoto, Yasuhiro Maeda and Yuji Miyahara: Simple and Robust Strategy for Potentiometric Detection of Glucose Using Fluorinated Phenylboronic Acid Self-assembled Monolayer. BBA - Gen. Subjects. 2013; 1830 (9): 4359-4364. ( DOI )

  49. Tatsuro Goda, Ankit Balram Singi, Yasuhiro Maeda, Akira Matsumoto, Masaki Torimura, Hiroshi Aoki and Yuji Miyahara: Label-free Potentiometry for Detecting DNA Hybridization using Peptide Nucleic Acid and DNA Probes. Sensors. 2013; 13 (2): 2267-2278. ( DOI )

  50. Atsushi Sato, Hiroshi Shibuya: WNK signaling is involved in neural development via Lhx8/Awh expression. PLoS ONE. 2013; 8 (1): e55301. ( PubMed , DOI )

  51. Yoshida S, Hosoya T: Synthesis of diverse aromatic oxophosphorus compounds by the Michaelis-Arbuzov-type reaction of arynes. Chem Lett. 2013; 42 (6): 583-585. ( DOI )

  52. Koyama H, Zhang Z, Ijuin R, Siqin, Son J, Hatta Y, Ohta M, Wakao M, Hosoya T, Doi H, Suzuki M.: Pd(0)-mediated rapid coupling of methyl iodide with excess amounts of benzyl- and cinnamylboronic acid esters: efficient method for incorporation of positron-emitting (11)C radionuclide into organic frameworks by coupling between two sp(3)-hybridized carbons. RSC Adv. 2013; 3 (24): 9391-9401. ( DOI )

  53. Toshiyasu Goto, Atsushi Sato, Masahiro Shimizu, Shungo Adachi, Kiyotoshi Satoh, Shun-ichiro Iemura, Tohru Natsume, Hiroshi Shibuya: IQGAP1 functions as a modulator of dishevelled nuclear localization in Wnt signaling. PLoS ONE. 2013; 8 (4): e60865. ( PubMed , DOI )

  54. Tetsuo Narumi, Haruo Aikawa, Tomohiro Tanaka, Chie Hashimoto, Nami Ohashi, Wataru Nomura, Takuya Kobayakawa, Hikaru Takano, Yuki Hirota, Tsutomu Murakami, Naoki Yamamoto & Hirokazu Tamamura: Low Molecular Weight CXCR4 Ligands with Variable Spacers. ChemMedChem,. 2013; 8 (1): 118-124.

  55. Tetsuo Narumi, Hiroshi Arai, Kazuhisa Yoshimura, Shigeyoshi Harada, Yuki Hirota, Nami Ohashi, Chie Hashimoto, Wataru Nomura, Shuzo Matsushita & Hirokazu Tamamura: CD4 Mimics as HIV Entry Inhibitors: Lead Optimization Studies of the Aromatic Substituents. Bioorg. Med. Chem.,. 2013; 21 (9): 2518-2526.

  56. Wataru Nomura, Chie Hashimoto, Takaharu Suzuki, Nami Ohashi, Masayuki Fujino, Tsutomu Murakami, Naoki Yamamoto & Hirokazu Tamamura: Multimerized CHR-derived Peptides as HIV-1 Fusion Inhibitors. Bioorg. Med. Chem.,. 2013; 21 (15): 4452-4458.

  57. Chie Hashimoto, Wataru Nomura, Tetsuo Narumi, Masayuki Fujino, Hiroshi Tsutsumi, Masaki Haseyama, Naoki Yamamoto, Tsutomu Murakami & Hirokazu Tamamura: Anti-HIV-1 Peptide Derivatives Based on the HIV-1 Co-receptor CXCR4. ChemMedChem,. 2013; 8 (10): 1668-1672.

  58. Wataru Nomura, Haruo Aikawa, Nami Ohashi, Emiko Urano, Mathieu Metifiot, Masayuki Fujino, Kasthuraiah Maddali, Taro Ozaki, Ami Nozue, Tetsuo Narumi, Chie Hashimoto, Tomohiro Tanaka, Yves Pommier, Naoki Yamamoto, Jun Komano, Tsutomu Murakami & Hirokazu Tamamura: Cell-Permeable Stapled Peptides Based on HIV-1 Integrase Inhibitors Derived from HIV-1 Gene Product. ACS Chem. Biol.,. 2013; 8 (10): 2235-2244.

  59. Hiroyuki Otsuki, Takayuki Hishiki, Tomoyuki Miura, Chie Hashimoto, Tetsuo Narumi, Hirokazu Tamamura, Kazuhisa Yoshimura, Shuzo Matsushita & Tatsuhiko Igarashi: Generation of a Replication-competent Simian–human Immunodeficiency Virus, the Neutralisation Sensitivity of Which can be Enhanced in the Presence of a Small Molecule CD4 Mimic. J. Gen. Virol.,. 2013; 94 (12): 2710-2716.

  60. Chie Hashimoto, Wataru Nomura, Tetsuo Narumi, Masayuki Fujino, Toru Nakahara, Naoki Yamamoto, Tsutomu Murakami & Hirokazu Tamamura: CXCR4-derived Synthetic Peptides Inducing Anti-HIV-1 Antibodies. Bioorg. Med. Chem.,. 2013; 21 (22): 6878-6885.

  61. Chie Hashimoto, Tetsuo Narumi, Hiroyuki Otsuki, Yuki Hirota, Hiroshi Arai, Kazuhisa Yoshimura, Shigeyoshi Harada, Nami Ohashi, Wataru Nomura, Tomoyuki Miura, Tatsuhiko Igarashi, Shuzo Matsushita & Hirokazu Tamamura: A CD4 Mimic as an HIV Entry Inhibitor: Pharmacokinetics. Bioorg. Med. Chem.,. 2013; 21 (24): 7884-7889.

  62. Aizawa H: Habenula and the asymmetric development of the vertebrate brain. Anat Sci Int.. 2013; 88 (1): 1-9.

  63. Hidenori Aizawa, Wanpeng Cui, Kohichi Tanaka, Hitoshi Okamoto: Hyperactivation of the habenula as a link between depression and sleep disturbance. Front Hum Neurosci. 2013; 7 826. ( PubMed , DOI )

  64. Aoki T, Kinoshita M, Aoki R, Agetsuma M, Aizawa H, Yamazaki M, Takahoko M, Amo R, Arata A, Higashijima S-I, Tsuboi T, Okamoto H.: Imaging of neural ensemble for the retrieval of a learned behavioral program. Neuron. 2013; 78 (5): 881-894.

  65. Higo Kunitake, Ikura Teikichi, Oda Masayuki, Morii Hisayuki, Takahashi Jun, Abe Ryo, Ito Nobutoshi: High resolution crystal structure of the Grb2 SH2 domain with a phosphopeptide derived from CD28. PLoS One. 2013; 8 (9): e74482. ( PubMed , DOI )

  1. Negishi Jun, Funamoto Seiichi, Kimura Tsuyoshi, Nam Kwangoo, Higami Tetsuya, Kishida Akio: Porcine radial artery decellularization by high hydrostatic pressure. J Tissue Eng Regen Med. 2012.12; ( PubMed , DOI )

  2. Goda Tatsuro, Masuno Kozue, Nishida Junko, Kosaka Nobuyoshi, Ochiya Takahiro, Matsumoto Akira, Miyahara Yuji: A label-free electrical detection of exosomal microRNAs using microelectrode array. Chem Commun (Camb). 2012.12; 48 (98): 11942-11944. ( PubMed , DOI )

  3. Toshiyuki Aodai,Toru Masuzawa,Kazuhide Ozeki,Akio Kishida,Tetsuya Higami: Effect of metal surface characteristics on the adhesion performance of the integrated low-level energies method of adhesion Jurnal of Artificial Organs. 2012.12; 15 (4): 386-394. ( DOI )

  4. Miki Nishio, Koichi Hamada, Kohichi Kawahara, Masato Sasaki, Fumihito Noguchi, Shuhei Chiba, Kensaku Mizuno, Satoshi O Suzuki, Youyi Dong, Masaaki Tokuda, Takumi Morikawa, Hiroki Hikasa, Jonathan Eggenschwiler, Norikazu Yabuta, Hiroshi Nojima, Kentaro Nakagawa, Yutaka Hata, Hiroshi Nishina, Koshi Mimori, Masaki Mori, Takehiko Sasaki, Tak W Mak, Toru Nakano, Satoshi Itami, Akira Suzuki: Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice. J. Clin. Invest.. 2012.12; 122 (12): 4505-4518. ( PubMed , DOI )

  5. Yasuda K, Hattori A, Hyonchol K, Terazono H, Hayashi M, Takei H, Kaneko T, Nomura F: Non-destructive on-chip imaging flow cell-sorting system for on-chip cellomics Microfluidics and Nanofluidics. 2012.12; 14 (6): 907-931. ( DOI )

  6. Goda Tatsuro, Miyahara Yuji: Interpretation of protein adsorption through its intrinsic electric charges: a comparative study using a field-effect transistor, surface plasmon resonance, and quartz crystal microbalance. Langmuir. 2012.10; 28 (41): 14730-14738. ( PubMed , DOI )

  7. Takahiro Kawashima,Yuhei Yamada,Yuuta Matsuzawa,Moeto Nagai,Takayui Shibata,Toru Masuzawa,Tsuyoshi Kimura,Akio Kishida: Development of Cell Culture Microdevice integrated with Piezoelectric Thin Film Actuator for On-Chip Regulation of Cell Functions Japanese Joumal of Applied Physics. 2012.10; 51 (10): ID107201-1-ID107201-8. ( DOI )

  8. Tetsuo Narumi, Takuya Kobayakawa, Haruo Aikawa, Shunsuke Seike, Hirokazu Tamamura: Stereoselective formation of trisubstituted (Z)-chloroalkenes adjacent to a tertiary carbon stereogenic center by organocuprate-mediated reduction/alkylation. Organic Letters. 2012.09; 14 (17): 4490-4493. ( PubMed , DOI )

  9. Yuya Hanazono, Kazuki Takeda, Masafumi Yohda, Kunio Miki: Structural studies on the oligomeric transition of a small heat shock protein, StHsp14.0. J Mol Biol. 2012.09; 422 (1): 100-108. ( PubMed , DOI )

  10. Goda Tatsuro, Maeda Yasuhiro, Miyahara Yuji: Simultaneous monitoring of protein adsorption kinetics using a quartz crystal microbalance and field-effect transistor integrated device. Anal Chem. 2012.09; 84 (17): 7308-7314. ( PubMed , DOI )

  11. Arakawa T, Wang X, Ando E, Endo H, Takahashi D, Kudo H, Saito H, Mitsubayashi K: A highly sensitive and temporal visualization system for gaseous ethanol with chemiluminescence enhancer. Luminescence. 2012.09; 27 (5): 328-333.

  12. Hiroshi Nishina: hDlk-1: a cell surface marker common to normal hepatic stem/progenitor cells and carcinomas. J. Biochem.. 2012.08; 152 (2): 121-123. ( PubMed , DOI )

  13. Yasuda K: On-Chip Cellomics: Constructive Understanding of Multicellular Network Using On-Chip Cellomics Technology Jpn J Appl Phys. 2012.08; 51 08KA03. ( DOI )

  14. Terazono H, Kim H, Hayashi M, Hattori A, Nomura F, Kaneko T, Yasuda K: A Non-Destructive Culturing and Cell Sorting Method for Cardiomyocytes and Neurons Using a Double Alginate Layer PLoS ONE. 2012.08; 7 (8): e42485. ( DOI )

  15. Yoshimura SH, Khan S, Ohno S, Yokogawa T, Nishikawa K, Hosoya T, Maruyama H, Nakayama Y, Takeyasu K: Site-specific attachment of a protein to a carbon nanotube end without loss of protein function. Bioconjug Chem. 2012.07; 23 (7): 1488-1493. ( PubMed , DOI )

  16. Hattori A, Yasuda K: Extended Depth of Field Optics for Precise Image Analysis in Microfluidic Flow Cytometry Jpn J Appl Phys. 2012.06; 51 06FK05. ( DOI )

  17. Terazono H, Hayashi M, Kim H, Hattori A, Yasuda K: Cell-Sorting System with On-Chip Imaging for Label-Free Shape-Based Selection of Cells Jpn J Appl Phys. 2012.06; 51 06FK08. ( DOI )

  18. Kim H, Takei H, Negishi T, Kudo M, Terazono H, Yasuda K: Contribution of Metal Layer Thickness for Quantitative Backscattered Electron Imaging of Field Emission Scanning Electron Microscopy e-J Surf Sci Nanotech (e-JSSNT). 2012.06; 10 301-304. ( DOI )

  19. Kim H, Terazono H, Hayashi M, Takei H, Yasuda K: Highly Sensitive Detection of Target Biomolecules on Cell Surface Using Gold Nanoparticle Conjugated with Aptamer Probe Jpn J Appl Phys. 2012.06; 51 06FH01. ( DOI )

  20. Shoji Hata, Jun Hirayama, Hiroaki Kajiho, Kentaro Nakagawa, Yutaka Hata, Toshiaki Katada, Makoto Furutani-Seiki, Hiroshi Nishina: A novel acetylation cycle of transcription co-activator Yes-associated protein that is downstream of Hippo pathway is triggered in response to SN2 alkylating agents. J. Biol. Chem.. 2012.06; 287 (26): 22089-22098. ( PubMed , DOI )

  21. Narumi T, Tanaka T, Hashimoto C, Nomura W, Aikawa H, Sohma A, Itotani K, Kawamata M, Murakami T, Yamamoto N, Tamamura H: Pharmacophore-based small molecule CXCR4 ligands. Bioorg Med Chem Lett. 2012.06; 22 (12): 4169-4172. ( PubMed , DOI )

  22. Kaori Taniguchi,Shinya Takizawa,Tomoya Hirano,Shigeru Murata,Hiroyuki Kagechika,Akio Kishida,Ayumi Ohsaki: Amarastelline A: A Fluorescent Alkaloid from Quassia amara and Its Properties in Living Cells Chem Plus Chem . 2012.06; 77 (6): 427-431. ( DOI )

  23. Mana Toma, Koji Toma, Pavel Adam, Jiří Homola, Wolfgang Knoll, Jakub Dostálek: Surface plasmon-coupled emission on plasmonic Bragg gratings Optics Express. 2012.06; 20 (13): 14042-14053. ( PubMed )

  24. Nomura F, Kaneko T, Hamada T, Hattori A, Yasuda K: Quantitative Evaluation of Closed-Loop-Shaped Cardiomyocyte Network by Using Ring-Shaped Electrode Jpn J Appl Phys. 2012.06; 51 06FK06. ( DOI )

  25. Kaneko T, Nomura F, Hattori A, Yasuda K: Improvement of Electrical Stimulation Protocol for Simultaneous Measurement of Extracellular Potential with On-Chip Multi-Electrode Array System Jpn J Appl Phys. 2012.06; 51 06FK02. ( DOI )

  26. Hamada T, Nomura F, Kaneko T, Yasuda K: Importance of Thickness in Human Cardiomyocyte Network for Effective Electrophysiological Stimulation Using On-Chip Extracellular Microelectrodes Jpn J Appl Phys. 2012.06; 51 06FK03. ( DOI )

  27. Ken Okada, Akihide Kamiya, Keiichi Ito, Ayaka Yanagida, Hidenori Ito, Hiroki Kondou, Hiroshi Nishina, Hiromitsu Nakauchi: Prospective isolation and characterization of bipotent progenitor cells in early mouse liver development. Stem Cells Dev.. 2012.05; 21 (7): 1124-1133. ( PubMed , DOI )

  28. Toshiyuki Oishi, Shuji Terai, Shinya Kuwashiro, Koichi Fujisawa, Toshihiko Matsumoto, Hiroshi Nishina, Isao Sakaida: Ezetimibe reduces fatty acid quantity in liver and decreased inflammatory cell infiltration and improved NASH in medaka model. Biochem. Biophys. Res. Commun.. 2012.05; 422 (1): 22-27. ( PubMed , DOI )

  29. Yasuda K: On-Chip Cellomics Assay Enabling Algebraic and Geometric Understanding of Epigenetic Information in Cellular Networks of Living Systems. 1. Temporal Aspects of Epigenetic Information in Bacteria Sensors. 2012.05; 12 (6): 7169-7206. ( DOI )

  30. Hashimoto C, Nomura W, Ohya A, Urano E, Miyauchi K, Narumi T, Aikawa H, Komano JA, Yamamoto N, Tamamura H: Evaluation of a synthetic C34 trimer of HIV-1 gp41 as AIDS vaccines. Bioorg Med Chem. 2012.05; 20 (10): 3287-3291. ( PubMed , DOI )

  31. Yoshimoto Nobuko, Sakamaki Yuta, Haeta Minoru, Kato Akira, Inaba Yuka, Itoh Toshimasa, Nakabayashi Makoto, Ito Nobutoshi, Yamamoto Keiko: Butyl pocket formation in the vitamin D receptor strongly affects the agonistic or antagonistic behavior of ligands. J Med Chem. 2012.05; 55 (9): 4373-4381. ( PubMed , DOI )

  32. Arakawa T, Ando E, Wang X, Kumiko M, Kudo H, Saito H, Mitani T, Takahashi M, Mitsubayashi K: A highly sensitive and temporal visualization system for gaseous ethanol with chemiluminescence enhancer. Luminescence. 2012.04; 27 (5): 328-333. ( PubMed , DOI )

  33. Y.Sawa、E.Tatsumi、T.Tsukiya、A.Funakubo、T.Horiuchi、K.Iwasaki、A.Kishida、T.Masuzawa、K.Matsuda、A.Myoui、M.Nishimura、T.Nishimura、S.Tokunaga、Y.Tomizawa、T.Tomo、T.Yamaoka: Journal of Artificial Organs 2011:the year in review J. Artif Organs. 2012.03; 15 (1): 11-19.

  34. Takuya Iwamoto, Shuji Terai, Yuko Mizunaga, Naoki Yamamoto, Kaoru Omori, Koichi Uchida, Takahiro Yamasaki, Yasuhiko Fujii, Hiroshi Nishina, Isao Sakaida: Splenectomy enhances the anti-fibrotic effect of bone marrow cell infusion and improves liver function in cirrhotic mice and patients. J. Gastroenterol.. 2012.03; 47 (3): 300-312. ( PubMed , DOI )

  35. Sumida Y, Kato T, Yoshida S, Hosoya T: Palladium-catalyzed regio- and stereoselective hydrosilylation of electron-deficient alkynes. Org Lett. 2012.03; 14 (6): 1552-1555. ( PubMed , DOI )

  36. Yoshimi Uchida, Tomomi Osaki, Tokiwa Yamasaki, Tadanori Shimomura, Shoji Hata, Kazumasa Horikawa, Shigenobu Shibata, Takeshi Todo, Jun Hirayama, Hiroshi Nishina: Involvement of stress kinase mitogen-activated protein kinase kinase 7 in regulation of mammalian circadian clock. J. Biol. Chem.. 2012.03; 287 (11): 8318-8326. ( PubMed , DOI )

  37. Goda Tatsuro, Miyahara Yuji: A hairpin DNA aptamer coupled with groove binders as a smart switch for a field-effect transistor biosensor. Biosens Bioelectron. 2012.02; 32 (1): 244-249. ( PubMed , DOI )

  38. Narumi T, Komoriya M, Hashimoto C, Wu H, Nomura W, Suzuki S, Tanaka T, Chiba J, Yamamoto N, Murakami T, Tamamura H: Conjugation of cell-penetrating peptides leads to identification of anti-HIV peptides from matrix proteins. Bioorg Med Chem. 2012.02; 20 (4): 1468-1474. ( PubMed , DOI )

  39. Nomura W, Hashimoto C, Ohya A, Miyauchi K, Urano E, Tanaka T, Narumi T, Nakahara T, Komano JA, Yamamoto N, Tamamura H: A synthetic C34 trimer of HIV-1 gp41 shows significant increase in inhibition potency. ChemMedChem. 2012.02; 7 (2): 205-208. ( PubMed , DOI )

  40. Nomura W, Masuda A, Ohba K, Urabe A, Ito N, Ryo A, Yamamoto N, Tamamura H: Effects of DNA binding of the zinc finger and linkers for domain fusion on the catalytic activity of sequence-specific chimeric recombinases determined by a facile fluorescent system. Biochemistry. 2012.02; 51 (7): 1510-1517. ( PubMed , DOI )

  41. Kwangwoo Nam, Yuuki Sakai, Yoshihide Hashimoto, Tsuyoshi Kimura, Akio Kishida: Fabrication of a heterostructural fibrillated collagen matrix for the regeneration of soft tissue function Soft Matter. 2012.01; 8 (2): 472-480. ( DOI )

  42. Adachi Takahiro, Harumiya Satoru, Takematsu Hiromu, Kozutsumi Yasunori, Wabl Matthias, Fujimoto Manabu, Tedder Thomas F: CD22 serves as a receptor for soluble IgM. Eur J Immunol. 2012.01; 42 (1): 241-247. ( PubMed , DOI )

  43. Akihiro Hattori, Kenji Yasuda: Evaluation of a Centrifuged Double Y-Shape Microfluidic Platform for Simple Continuous Cell Environment Exchange. International Journal of Molecular Sciences. 2012.01; 13 1. ( DOI )

  44. Tamashiro Tomonari, Tanabe Yoichi, Ikura Teikichi, Ito Nobutoshi, Oda Masayuki: Critical roles of Asp270 and Trp273 in the alpha-repeat of the carbohydrate-binding module of endo-1,3-beta-glucanase for laminarin-binding avidity. Glycoconj J. 2012.01; 29 (1): 77-85. ( PubMed , DOI )

  45. Wongmayura A, Fujii S, Ito S, Kano A, Taoda Y., Kawachi E, Kagechika H, Tanatani A: Novel vitamin D receptor ligands bearing a spherical hydrophobic core structure-Comparison of bicyclic hydrocarbon derivatives with boron cluster derivatives. Bioorganic and Medicinal Chemistry Letters. 2012; 22 1756-1760.

  46. Murakami Y, Kawata A, Seki Y, Koh T, Yuhara K, Maruyama T, MachinoM, Ito S, Kadoma Y, Fujisawa S.: Comparative inhibitory effects of magnolol, honikiol, eugenol, and bis-eugenol on cyclooxygenase-2 expression and nucleo factor kappa B activation in RAW 264.7 cells stimulated with fimriae of Prophyromonas gingivalis. in vivo. 2012; 26 941-950.

  47. Mitsuru Naito, Takehiko Ishii, Akira Matsumoto, Kanjiro Miyata, Yuji Miyahara and Kazunori Kataoka: A Phenylboronate-Functionalized Polyion Complex Micelle for ATP-Triggered Release of siRNA. Angew. Chem. Int. Ed.. 2012; 51 (43): 10751-10755. ( DOI )

  48. Tatsuro Goda, Kozue Masuno, Junko Nishida, Nobuyoshi Kosaka, Takahiro Ochiya, Akira Matsumoto and Yuji Miyahara: A Label-free Electrical Detection of Exosomal microRNAs using Microelectrode Array. Chem. Commun.. 2012; 48 (98): 11942-11944. ( DOI )

  49. Akira Matsumoto, Takehiko Ishii, Junko Nishida, Hiroko Matsumoto, Kazunori Kataoka and Yuji Miyahara: A Synthetic Approach Toward Self-regulated Insulin Delivery System. Angew. Chem. Int. Ed.. 2012; 51 (9): 2124-2128. ( DOI )

  50. Yasuhiro Maeda, Akira Matsumoto, Yoshiko Miura and Yuji Miyahara: Preparation of alpha-Mannoside Hydrogel and Electrical Detection of Saccharide-protein Interactions using the Smart Gel-modified Gate Field Effect Transistor. Nanoscale Res. Lett.. 2012; 7 108. ( DOI )

  51. Schaffhauser Daniel Felix, Patti Monica, Goda Tatsuro, Miyahara Yuji, Forster Ian Cameron, Dittrich Petra Stephanie: An integrated field-effect microdevice for monitoring membrane transport in Xenopus laevis oocytes via lateral proton diffusion. PLoS One. 2012; 7 (7): e39238. ( PubMed , DOI )

  52. Tokiwa Yamasaki, Hiroshi Kawasaki, Hiroshi Nishina: Diverse Roles of JNK and MKK Pathways in the Brain. J Signal Transduct. 2012; 2012 459265. ( PubMed , DOI )

  53. Yuko Mizunaga, Shuji Terai, Naoki Yamamoto, Koichi Uchida, Takahiro Yamasaki, Hiroshi Nishina, Yusuke Fujita, Koh Shinoda, Yoshihiko Hamamoto, Isao Sakaida: Granulocyte colony-stimulating factor and interleukin-1β are important cytokines in repair of the cirrhotic liver after bone marrow cell infusion: comparison of humans and model mice. Cell Transplant. 2012; 21 (11): 2363-2375. ( PubMed , DOI )

  54. Tadashi Yokoi, Yuko Seko, Tae Yokoi, Hatsune Makino, Shin Hatou, Masakazu Yamada, Tohru Kiyono, Akihiro Umezawa, Hiroshi Nishina, Noriyuki Azuma: Establishment of functioning human corneal endothelial cell line with high growth potential. PLoS ONE. 2012; 7 (1): e29677. ( PubMed , DOI )

  55. Tetsuo Narumi, Takuya Kobayakawa, Haruo Aikawa, Shunsuke Seike & Hirokazu Tamamura: Stereoselective Formation of Trisubstituted (Z)-Chloroalkenes Adjacent to a Tertiary Carbon Stereogenic Center by Organocuprate-Mediated Reduction/Alkylation. Org. Lett., 14(17), 4490-4493. 2012; 14 (17): 4490-4493.

  56. Aizawa H, Kobayashi M, Tanaka S, Fukai T, Okamoto H.: Molecular characterization of the subnuclei in rat habenula. J Comp Neurol.. 2012; 520 4051-4066.

  57. Maung Kyi Chan Ko, Shinobu Ikeda, Makiko Mieno-Naka, Tomio Arai, Syed Ali Hyder Zaidi, Noriko Sato, Masaaki Muramatsu and Motoji Sawabe: Association of COMT Gene Polymorphisms with Systemic Atherosclerosis in Elderly Japanese. Journal of Atherosclerosis and Thrombosis. 2012; 19 (6): 552-8.

  58. Ayumi Ohsaki,Masaaki Ozawa,Kanki Komiyama,Akio Kishida,Takahiko Isobe: The Cytotoxic Activity of Diterpenoids from Isodon species Natural Product Communications. 2012; 7 (8): 977-978.

  59. Hitomi Yuki, Adachi Takahiro, Tsuchiya Naoyuki, Honda Zen-Ichiro, Tokunaga Katsushi, Tsubata Takeshi: Human CD72 splicing isoform responsible for resistance to systemic lupus erythematosus regulates serum immunoglobulin level and is localized in endoplasmic reticulum. BMC Immunol. 2012; 13 72. ( PubMed , DOI )

  1. Naoko NAKAMURA、Kwangwoo NAM、Tsuyoshi KIMURA、Tooru MASUZAWA、Toshiyuki OKADA、Akio KISHIDA: Surface characteristics and bonding of medical polymeric material Annual Reports of the Institute of Biomaterials and Bioengineering. 2011.12; 45 14-16.

  2. Hiroshi Yukiura, Kotaro Hama, Keita Nakanaga, Masayuki Tanaka, Yoichi Asaoka, Shinichi Okudaira, Naoaki Arima, Asuka Inoue, Takafumi Hashimoto, Hiroyuki Arai, Atsuo Kawahara, Hiroshi Nishina, Junken Aoki: Autotaxin regulates vascular development via multiple lysophosphatidic acid (LPA) receptors in zebrafish. J. Biol. Chem.. 2011.12; 286 (51): 43972-43983. ( PubMed , DOI )

  3. K Nam,Y Tsutsumi,C Yoshikawa,Y Tanaka,R Fukaya,T Kimura,H kobayashi,T Hanawa,A Kishida: Preparation of novel polymer-metal oxide nanocomposites with nanophase separated hierarchical structure Bulletin of Materials Science. 2011.12; 34 (7): 1289-1296.

  4. Ozawa M, Takahashi K, Akazawa KH, Takashima T, Nagata H, Doi H, Hosoya T, Wada Y, Cui Y, Kataoka Y, Watanabe Y: PET of aromatase in gastric parietal cells using 11C-vorozole. J Nucl Med. 2011.12; 52 (12): 1964-1969. ( PubMed , DOI )

  5. Nomura F, Kaneko T, Hattori A, Yasuda K: Label-free shape-based selection of cardiomyocytes with on-chip imaging cell sorting system Journal of Bioprocessing & Biotechniques. 2011.12; S3 (3): 1-6. ( DOI )

  6. Fujii Shinya, Masuno Hiroyuki, Taoda Yoshiyuki, Kano Atsushi, Wongmayura Angsuma, Nakabayashi Makoto, Ito Nobutoshi, Shimizu Masato, Kawachi Emiko, Hirano Tomoya, Endo Yasuyuki, Tanatani Aya, Kagechika Hiroyuki: Boron cluster-based development of potent nonsecosteroidal vitamin D receptor ligands: direct observation of hydrophobic interaction between protein surface and carborane. J Am Chem Soc. 2011.12; 133 (51): 20933-20941. ( PubMed , DOI )

  7. Yamasaki T, Kawasaki H, Arakawa S, Shimizu K, Shimizu S, Reiner O, Okano H, Nishina S, Azuma N, Penninger JM, Katada T, Nishina H: Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex. J Neurosci. 2011.11; 31 (46): 16872-16883. ( PubMed , DOI )

  8. Miyajima K, Itabashi G, Koshida T, Tamari K, Takahashi D, Arakawa T, Kudo H, Saito H, Yano K, Shiba K, Mitsubayashi K: Fluorescence immunoassay using an optical fiber for determination of Dermatophagoides farinae (Der f1). Environ Monit Assess. 2011.11; 182 (1-4): 233-241. ( PubMed , DOI )

  9. Kudo H, Wang X, Suzuki Y, Ye M, Yamashita T, Gessei T, Miyajima K, Arakawa T, Mitsubayashi K: Fiber-optic biochemical gas sensor (bio-sniffer) for sub-ppb monitoring of formaldehyde vapor Sensors and Actuators B. 2011.11; 161 486-492.

  10. Narumi T, Arai H, Yoshimura K, Harada S, Nomura W, Matsushita S, Tamamura H: Small molecular CD4 mimics as HIV entry inhibitors. Bioorg Med Chem. 2011.11; 19 (22): 6735-6742. ( PubMed , DOI )

  11. Nishi Y, Kawazu H, Takei H, Iwata K, Kudo H, Mitsubayashi K: Effects of electron beam irradiation on peeling resistance of laminated sheet of high strength polypropylene (PP) and bio-adaptable polydimethylsiloxane (PDMS). Materials Transactions. 2011.10; 52 (-10): 1943-1948.

  12. Yoshihide Hashimoto, Seiichi Funamoto, Tsuyoshi Kimura, Kwangwoo Nam, Toshiya Fujisato, Akio Kishida: The effect of decellularized bone/bone marrow produced by high-hydrostatic pressurization on the osteogenic differentiation of mesenchymal stem cells Biomaterials. 2011.10; 32 (29): 7060-7067. ( PubMed , DOI )

  13. Takuro Hisanaga, Shuji Terai, Takuya Iwamoto, Taro Takami, Naoki Yamamoto, Tomoaki Murata, Toshifumi Matsuyama, Hiroshi Nishina, Isao Sakaida: TNFR1-mediated signaling is important to induce the improvement of liver fibrosis by bone marrow cell infusion. Cell Tissue Res.. 2011.10; 346 (1): 79-88. ( PubMed , DOI )

  14. Hashimoto C, Tanaka T, Narumi T, Nomura W, Tamamura H: The successes and failures of HIV drug discovery. Expert Opin Drug Discov. 2011.10; 6 (10): 1067-1090. ( PubMed , DOI )

  15. Wang X, Ando E, Takahashi D, Arakawa T, Kudo H, Saito H, Mitsubayashi K: Non-invasive spatial visualization system of exhaled ethanol for real-time analysis of ALDH2 related alcohol metabolism. Analyst. 2011.09; 136 (18): 3680-3685. ( PubMed , DOI )

  16. Jun Negishi,Seiichi Funamoto,Tsuyoshi Kimura,Kwangoo Nam,Tetsuya Higami,Akio Kishida: Effect of the treatment temperature on collagen structures of the decellularized carotid artery using high-hydrostatic pressure Journal of Artificial Organs. 2011.09; 14 (3): 223-231. ( DOI )

  17. Nomura F, Kaneko T, Hattori A, Yasuda K: On-chip constructive cell-network study (II): on-chip quasi-in vivo cardiac toxicity assay for ventricular tachycardia/fibrillation measurement using ring-shaped closed circuit microelectrode with lined-up cardiomyocyte cell network. J Nanobiotechnology. 2011.09; 9 39. ( PubMed , DOI )

  18. Chu M, Shirai T, Takahashi D, Arakawa T, Kudo H, Sano K, Sawada S, Yano K, Iwasaki Y, Akiyoshi K, Mochizuki M, Mitsubayashi K: Biomedical soft contact-lens sensor for in situ ocular biomonitoring of tear contents. Biomed Microdevices. 2011.08; 13 (4): 603-611. ( PubMed , DOI )

  19. Yijun Bao, Kentaro Nakagawa, Zeyu Yang, Mitsunobu Ikeda, Kanchanamala Withanage, Mari Ishigami-Yuasa, Yukiko Okuno, Shoji Hata, Hiroshi Nishina, Yutaka Hata: A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription. J. Biochem.. 2011.08; 150 (2): 199-208. ( PubMed , DOI )

  20. Matsukura H, Aisaki K, Igarashi K, Matsushima Y, Kanno J, Muramatsu M, Sudo K, Sato N: Genistein promotes DNA demethylation of the steroidogenic factor 1 (SF-1) promoter in endometrial stromal cells. Biochem Biophys Res Commun. 2011.08; 412 (2): 366-372. ( PubMed , DOI )

  21. Kaneko Tomoyuki, Nomura Fumimasa, Yasuda Kenji: Orientation and Community Size Dependences of Pulsatile Electrical Field Stimulation on Lined-Up and Rod-Shaped Single Cardiomyocytes. Jpn J Appl Phys. 2011.08; 50 (8): 80220. ( DOI )

  22. Yamada M, Kubo H, Kobayashi S, Ishizawa K, He M, Suzuki T, Fujino N, Kunishima H, Hatta M, Nishimaki K, Aoyagi T, Tokuda K, Kitagawa M, Yano H, Tamamura H, Fujii N, Kaku M: The increase in surface CXCR4 expression on lung extravascular neutrophils and its effects on neutrophils during endotoxin-induced lung injury. Cell Mol Immunol. 2011.07; 8 (4): 305-314. ( PubMed , DOI )

  23. Daiki Taneichi, Kenta Iijima, Akihiro Doi, Takayoshi Koyama, Yuzuru Minemoto, Kenzo Tokunaga, Mari Shimura, Shigeyuki Kano, Yukihito Ishizaka: Identification of SNF2h, a chromatin-remodeling factor, as a novel binding protein of Vpr of human immunodeficiency virus type 1. J Neuroimmune Pharmacol. 2011.06; 6 (2): 177-187. ( PubMed , DOI )

  24. Hayashi Masahito, Hattori Akihiro, Kim Hyonchol, Terazono Hideyuki, Kaneko Tomoyuki, Yasuda Kenji: Fully Automated On-Chip Imaging Flow Cytometry System with Disposable Contamination-Free Plastic Re-Cultivation Chip. International Journal of Molecular Sciences. 2011.06; 12 (6): 3618-3634. ( DOI )

  25. Kim Hyonchol, Hayashi Masahito, Terazono Hideyuki, Takei Hiroyuki, Yasuda Kenji: Production of Double-Layered Metal Nanocups for Artificial Nanospace of Biomolecular Reaction. Jpn J Appl Phys. 2011.06; 50 06GJ03. ( DOI )

  26. Terazono Hideyuki, Hayashi Masahito, Kim Hyonchol, Hattori Akihiro, Kaneko Tomoyuki, Yasuda Kenji: Image-Based Identification of Single Neurons for Noninvasive Imaging Purification. Jpn J Appl Phys. 2011.06; 50 06GL07. ( DOI )

  27. Hattori Akihiro, Kaneko Tomoyuki, Yasuda Kenji: Improvement of Particle Alignment Control and Precise Image Acquisition for On-Chip High-Speed Imaging Cell Sorter. Jpn J Appl Phys. 2011.06; 50 06GL06. ( DOI )

  28. Hayashi Masahito, Kaneko Tomoyuki, Yasuda Kenji: Continuous Concentration and Separation of Microparticles Using Dielectrophoretic Force in a V-Shaped Electrode Array. Jpn J Appl Phys. 2011.06; 50 06GL03. ( DOI )

  29. Koji Toma, Jakub Dostalek, Wolfgang Knoll: Long range surface plasmon-coupled fluorescence emission for biosensor applications Optics Express. 2011.06; 19 (12): 11090-11099. ( PubMed )

  30. Xu C, Liu J, Chen L, Liang S, Fujii N, Tamamura H, Xiong H: HIV-1 gp120 enhances outward potassium current via CXCR4 and cAMP-dependent protein kinase A signaling in cultured rat microglia. Glia. 2011.06; 59 (6): 997-1007. ( PubMed , DOI )

  31. Okamoto H, Agetsuma M, Aizawa H: Genetic dissection of the zebrafish habenula, a possible switching board for selection of behavioral strategy to cope with fear and anxiety. Dev Neurobiol. 2011.05; ( PubMed , DOI )

  32. Goda Tatsuro, Miyahara Yuji: Thermo-responsive molecular switches for ATP using hairpin DNA aptamers. Biosens Bioelectron. 2011.05; 26 (9): 3949-3952. ( PubMed , DOI )

  33. Takahashi K, Onoe K, Doi H, Nagata H, Yamagishi G, Hosoya T, Tamura Y, Wada Y, Yamanaka H, Yokoyama C, Mizuma H, Takashima T, Bergström M, Onoe H, Långström B, Watanabe Y: Increase in hypothalamic aromatase in macaque monkeys treated with anabolic-androgenic steroids: PET study with [11C]vorozole. NeuroReport. 2011.05; 22 (7): 326-330. ( PubMed , DOI )

  34. Nomura W, Ohashi N, Okuda Y, Narumi T, Ikura T, Ito N, Tamamura H: Fluorescence-quenching screening of protein kinase C ligands with an environmentally sensitive fluorophore. Bioconjug Chem. 2011.05; 22 (5): 923-930. ( PubMed , DOI )

  35. Masaaki Ozawa,Akio Kishida,Ayumi Ohsaki: Erythrinan Alkaloids from Seeds of Erythrina velutina Chemical and Pharmaceutical Bulletin. 2011.05; 59 (5): 564-567. ( DOI )

  36. Tanaka T, Narumi T, Ozaki T, Sohma A, Ohashi N, Hashimoto C, Itotani K, Nomura W, Murakami T, Yamamoto N, Tamamura H: Azamacrocyclic metal complexes as CXCR4 antagonists. ChemMedChem. 2011.05; 6 (5): 834-839. ( PubMed , DOI )

  37. Kaneko T, Nomura F, Yasuda K: On-chip Constructive Cell-Network Study (I): Contribution of cardiac fibroblasts to cardiomyocyte beating synchronization and community effect. Journal of nanobiotechnology. 2011.05; 9 (1): 21. ( PubMed , DOI )

  38. Kenji yamamoto,Tsuyoshi Kimura,Kwangwoo Nam,Seiichi Funamoto,Yukiko Ito,Kumiko Shiba,Ayako Katoh,Shigeru Shimizu,Kimio Kurita,Tetsua Higami,Toru Masuzawa,Akio Kishida: Synthetic polymer-tissue adhension using an ultrasonic scalpel Surgical Endoscopy . 2011.04; 25 (4): 1270-1275. ( DOI )

  39. Kazuki Takeda, Takuro Hayashi, Tetsuya Abe, Yu Hirano, Yuya Hanazono, Masafumi Yohda, Kunio Miki: Dimer structure and conformational variability in the N-terminal region of an archaeal small heat shock protein, StHsp14.0. J Struct Biol. 2011.04; 174 (1): 92-99. ( PubMed , DOI )

  40. Norio Miyamura, Takashi Nakamura, Naoko Goto-Inoue, Nobuhiro Zaima, Takahiro Hayasaka, Tokiwa Yamasaki, Shuji Terai, Isao Sakaida, Mitsutoshi Setou, Hiroshi Nishina: Imaging mass spectrometry reveals characteristic changes in triglyceride and phospholipid species in regenerating mouse liver. Biochem. Biophys. Res. Commun.. 2011.04; 408 (1): 120-125. ( PubMed , DOI )

  41. Shinya Takahashi, Kyoko Sakurai, Arisa Ebihara, Hiroaki Kajiho, Kota Saito, Kenji Kontani, Hiroshi Nishina, Toshiaki Katada: RhoA activation participates in rearrangement of processing bodies and release of nucleated AU-rich mRNAs. Nucleic Acids Res.. 2011.04; 39 (8): 3446-3457. ( PubMed , DOI )

  42. S Takahashi, A Ebihara, H Kajiho, K Kontani, H Nishina, T Katada: RASSF7 negatively regulates pro-apoptotic JNK signaling by inhibiting the activity of phosphorylated-MKK7. Cell Death Differ.. 2011.04; 18 (4): 645-655. ( PubMed , DOI )

  43. Shinya Kuwashiro, Shuji Terai, Toshiyuki Oishi, Koichi Fujisawa, Toshihiko Matsumoto, Hiroshi Nishina, Isao Sakaida: Telmisartan improves nonalcoholic steatohepatitis in medaka (Oryzias latipes) by reducing macrophage infiltration and fat accumulation. Cell Tissue Res.. 2011.04; 344 (1): 125-134. ( PubMed , DOI )

  44. Arakawa T, Noguchi M, Sumitomo K, Yamaguchi Y, Shoji S: High-throughput single-cell manipulation system for a large number of target cells. Biomicrofluidics. 2011.04; 5 (1): 14114. ( PubMed , DOI )

  45. Arakawa T, Koshida T, Gessei T, Miyajima K, Takahashi D, Kudo H, Yano K, Mitsubayashi: Biosensor for L-phenylalanine based on the optical detection of NADH using a UV light emitting diode. Mikrochim Acta. 2011.04; 173 199-205. ( DOI )

  46. Mana Toma, Koji Toma, Kanae Michioka, Yasuhiro Ikezoe, Daiki Obara, Koichi Okamoto, Kaoru Tamada: Collective plasmon modes excited on a silver nanoparticle 2D crystalline sheet Physical Chemistry Chemical Physics. 2011.04; 13 (16): 7459-7466. ( PubMed , DOI )

  47. Kaneko Tomoyuki, Nomura Fumimasa, Yasuda Kenji: Quasi-In vivo Heart Electrocardiogram Measurement of ST Period Using Convolution of Cell Network Extracellular Field Potential Propagation in Lined-Up Cardiomyocyte Cell-Network Circuit. Jpn J Appl Phys. 2011.04; 50 70213. ( DOI )

  48. Y.Sawa、E.Tatsumi、A.Funakubo、T.Horiuchi、K.Iwasaki、A.Kishida、T.Masuzawa、K.Matsuda、A.Myoui、M.Nishimura、T.Nishimura、S.Tokunaga、T.Tomo、T.Tsukiya、T.Yamaoka: Journal of Artificial Organs 2010:the year in review J. Artif Organs. 2011.03; 14 (1): 1-8.

  49. S.Mutsuo,K.Yamamoto,T.Furuzono,T.Kimura,T.Ono,A.Kishida: Release behavior from hydrogen-bonded polymer gels prepared by pressurization Journal of Applied Polymer Science . 2011.03; 119 (5): 2725-2729. ( DOI )

  50. Yukiko Ito,Tsuyoshi Kimura,Kwangwoo Nam,Ayako Katoh,Toru Masuzawa,Akio Kishida: Effects of Vibration on Differntiation of Cultured PC12 Cells Biotechnology and Bioengineering . 2011.03; 108 (3): 592-599. ( DOI )

  51. Bonanni Alessandra, Pumera Martin, Miyahara Yuji: Influence of gold nanoparticle size (2-50 nm) upon its electrochemical behavior: an electrochemical impedance spectroscopic and voltammetric study. Phys Chem Chem Phys. 2011.03; 13 (11): 4980-4986. ( PubMed , DOI )

  52. Kim H, Negishi T, Kudo M, Takei H, Yasuda K: Backscattered Electron Contrast Imaging of Scanning Electron Microscopy for Identifying Double Layered Nano-Scale Elements. Journal of Surface Analysis. 2011.03; 17 (3): 341-345.

  53. Nomura W, Narumi T, Ohashi N, Serizawa Y, Lewin NE, Blumberg PM, Furuta T, Tamamura H: Synthetic caged DAG-lactones for photochemically controlled activation of protein kinase C. Chembiochem. 2011.03; 12 (4): 535-539. ( PubMed , DOI )

  54. Ayumi Ohsaki,Shunsuke Kawamata,Masaaki Ozawa,Akio Kishida,Xun Gong,Chiaki Kuroda: Salviskinone A,a diterpene with a new skelton from Salvia Prezawalskii Tetrahedron Letters. 2011.03; 52 (12): 1375-1377. ( DOI )

  55. Tsutsumi H, Abe S, Mino T, Nomura W, Tamamura H: Intense blue fluorescence in a leucine zipper assembly. Chembiochem. 2011.03; 12 (5): 691-694. ( PubMed , DOI )

  56. Takahashi K, Yamagishi G, Hiramatsu T, Hosoya A, Onoe K, Doi H, Nagata H, Wada Y, Onoe H, Watanabe Y, Hosoya T: Practical synthesis of precursor of [N-methyl-11C]vorozole, an efficient PET tracer targeting aromatase in the brain. Bioorg Med Chem. 2011.02; 19 (4): 1464-1470. ( PubMed , DOI )

  57. Chu MX, Miyajima K, Takahashi D, Arakawa T, Sano K, Sawada S, Kudo H, Iwasaki Y, Akiyoshi K, Mochizuki M, Mitsubayashi K: Soft contact lens biosensor for in situ monitoring of tear glucose as non-invasive blood sugar assessment. Talanta. 2011.01; 83 (3): 960-965. ( PubMed , DOI )

  58. Arakawa T, Koshida T, Gessei T, Takahashi D, Kudo H, Yano K, Mitsubayashi K: Biosensor for L-phenylalanine based on the optical detection of NADH using a UV light emitting diode. Microchimica Acta. 2011.01; 173 (1-2): 199-205.

  59. Hiroshi Hanafusa, Kouki Ishikawa, Shin Kedashiro, Tsukasa Saigo, Shun-Ichiro Iemura, Tohru Natsume, Masayuki Komada, Hiroshi Shibuya, Atsuki Nara, Kunihiro Matsumoto: Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor. Nat Commun. 2011.01; 2 158. ( PubMed , DOI )

  60. Ohashi N, Nomura W, Narumi T, Lewin NE, Itotani K, Blumberg PM, Tamamura H: Fluorescent-responsive synthetic C1b domains of protein kinase Cdelta as reporters of specific high-affinity ligand binding. Bioconjug Chem. 2011.01; 22 (1): 82-87. ( PubMed , DOI )

  61. Hidenori Aizawa, Ryunosuke Amo, Hitoshi Okamoto: Phylogeny and ontogeny of the habenular structure. Front Neurosci. 2011; 5 138. ( PubMed , DOI )

  62. Takechi S, Ito S, Kashige N, Ishida T, Yamaguchi T: Glutathion depression by dihydropyrazine derivative. The journal of Toxicological Sciences. 2011; 36 (2): 231-235.

  63. Iwashita M, Fujii S, Ito S, Hirano T, Kagechika H: Efficient and Diversity-Oriented Total Synthesis of Riccardin C and Applicaton to Develop Novel Macrolactam Drivatives. Tetrahedron. 2011; 67 (33): 6073-6082.

  64. Brooke Beier, Katherine Musick, Akira Matsumoto, Alyssa Panitch, Eric Nauman, Pedro Irazoqui: Toward a Continuous Intravascular Glucose Monitoring System. Sensors. 2011; 11 409-424. ( DOI )

  65. Tomomi Osaki, Yoshimi Uchida, Jun Hirayama, Hiroshi Nishina: Diphenyleneiodonium chloride, an inhibitor of reduced nicotinamide adenine dinucleotide phosphate oxidase, suppresses light-dependent induction of clock and DNA repair genes in zebrafish. Biol. Pharm. Bull.. 2011; 34 (8): 1343-1347. ( PubMed )

  66. Yukiko Ito ,Tsuyoshi Kimura,Yusuke Ago,Kwangoo Nam,Kaori Hiraku,Kozo Miyazaki,Toru Masuzawa,Akio Kishida: Nano-vibration effect on cell adhesion and its shape Bio-Medical Materials and Engineering. 2011; 21 (3): 149-158. ( DOI )

  67. Tsuyoshi Kimura,Yoichi Nibe,Seiichi Funamoto,Masahiro Okada,Tsutomu Furuzono,Tsutomu Ono,Hidekazu Yoshizawa,Toshiya Fujisato,Kwangwoo Nam ,Akio Kishida: Preparation of a Nanoscaled Poly(vinyl alcohol)/Hydroxyapatite/DNA Complex Using High Hydrostatic Pressure Technology for In Vitro and In Vivo Gene Delivery Journal of Drug Delivery. 2011; 2011 ( DOI )

  68. Kwangwoo Nam,Yuuki Sakai,Seiichi Funamoto,Tsyoshi Kimura,Akio Kishida: Engineering a Collagen Matrix that Replicates the Biological Properties of Native extracellular Matrix Journal of Biomaterials Science. 2011; 22 (15): 1963-1892. ( DOI )

  69. Yoshida S, Shiraishi A, Kanno K, Matsushita T, Johmoto K, Uekusa H, Hosoya T: Enhanced clickability of doubly sterically-hindered aryl azides. Sci Rep. 2011; 1 82. ( PubMed , DOI )

  70. Anwar A, Hosoya T, Leong KM, Onogi H, Okuno Y, Hiramatsu T, Koyama H, Suzuki M, Hagiwara M, Garcia-Blanco MA: The kinase inhibitor SFV785 dislocates dengue virus envelope protein from the replication complex and blocks virus assembly. PLoS ONE. 2011; 6 (8): e23246. ( PubMed , DOI )

  71. Islam MS, Nagasaka R, Ohara K, Hosoya T, Ozaki H, Ushio H, Hori M: Biological abilities of rice bran-derived antioxidant phytochemicals for medical therapy. Curr Top Med Chem. 2011; 11 (14): 1847-1853. ( PubMed )

  72. Sakai D, Kii I, Nakagawa K, Matsumoto HN, Takahashi M, Yoshida S, Hosoya T, Takakuda K, Kudo A: Remodeling of actin cytoskeleton in mouse periosteal cells under mechanical loading induces periosteal cell proliferation during bone formation. PLoS ONE. 2011; 6 (9): e24847. ( PubMed , DOI )

  73. Noriko Sato, Naomi Yamakawa, Moe Masuda, Katsuko Sudo, Izuho Hatada and Masaaki Muramatsu: Genome-Wide DNA Methylation Analysis Reveals Phytoestrogen Modification of Promoter Methylation Patterns during Embryonic Stem Cell Differentiation. PLoS ONE. 2011; 6 (4): e19278. ( PubMed )

  74. Isagawa T, Nagae G, Shiraki N, Fujita T, Sato N, Ishikawa S, Kume S, Aburatani H.: DNA methylation profiling of embryonic stem cell differentiation into the three germ layers. PLoS One. 2011; 6 (10): e26052. ( PubMed )

  1. Jun Negishi,Kwangwoo Nam,Tsuyoshi Kimura,Toshiya Fujisato,Akio Kishida: High-hydrostatic pressure technique is an effective method for the preparation of PVA-heparin hybrid gel European Journal of Pharmaceutical Sciences . 2010.12; 41 (5): 617-622. ( DOI )

  2. Kato R, Munkhjargal M, Takahashi D, Arakawa T, Kudo H, Mitsubayashi K: An autonomous drug release system based on chemo-mechanical energy conversion "Organic Engine" for feedback control of blood glucose. Biosensors and Bioelectronics. 2010.12; 26 (4): 1455-1459. ( PubMed , DOI )

  3. Inouye S, Iimori R, Sahara Y, Hisada S, Hosoya T: Application of new semisynthetic aequorins with long half-decay time of luminescence to G-protein-coupled receptor assay. Anal Biochem. 2010.12; 407 (2): 247-252. ( PubMed , DOI )

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  6. Jinzhan Wu, Junko Kubota, Jun Hirayama, Yoko Nagai, Sachiko Nishina, Tadashi Yokoi, Yoichi Asaoka, Jungwon Seo, Nao Shimizu, Hiroaki Kajiho, Takashi Watanabe, Noriyuki Azuma, Toshiaki Katada, Hiroshi Nishina: p38 Mitogen-activated protein kinase controls a switch between cardiomyocyte and neuronal commitment of murine embryonic stem cells by activating myocyte enhancer factor 2C-dependent bone morphogenetic protein 2 transcription. Stem Cells Dev.. 2010.11; 19 (11): 1723-1734. ( PubMed , DOI )

  7. Sasaki Shigeo, Okabe Satoshi, Miyahara Yuji: Thermodynamic properties of N-isopropylacrylamide in water: solubility transition, phase separation of supersaturated solution, and glass formation. J Phys Chem B. 2010.11; 114 (46): 14995-15002. ( PubMed , DOI )

  8. Abe Y, Okumura E, Hosoya T, Hirota T, Kishimoto T: A single starfish Aurora kinase performs the combined functions of Aurora-A and Aurora-B in human cells. J Cell Sci. 2010.11; 123 (Pt 22): 3978-3988. ( PubMed , DOI )

  9. Toshiyasu Goto, Akimasa Fukui, Hiroshi Shibuya, Ray Keller, Makoto Asashima: Xenopus furry contributes to release of microRNA gene silencing. Proc. Natl. Acad. Sci. U.S.A.. 2010.11; 107 (45): 19344-19349. ( PubMed , DOI )

  10. Satoshi Katano, Koji Toma, Mana Toma, Kaoru Tamada, Yoichi Uehara: Nanoscale coupling of photons to vibrational excitation of Ag nanoparticle 2D array studied by scanning tunneling microscope light emission spectroscopy Physical Chemistry Chemical Physics. 2010.11; 12 (44): 14749-14753. ( PubMed , DOI )

  11. Tanaka T, Nomura W, Narumi T, Masuda A, Tamamura H: Bivalent ligands of CXCR4 with rigid linkers for elucidation of the dimerization state in cells. J Am Chem Soc. 2010.11; 132 (45): 15899-15901. ( PubMed , DOI )

  12. Goda T, Miyahara Y: Molecularly Engineered Charge-Conversion of Proteins for Sensitive Biosensing Anal Chem. 2010.11; 82 (21): 8946-8953.

  13. Yoichi Asaoka, Hiroshi Nishina: Diverse physiological functions of MKK4 and MKK7 during early embryogenesis. J. Biochem.. 2010.10; 148 (4): 393-401. ( PubMed , DOI )

  14. Sugino H, Arakawa T, Nara Y, Shirasaki Y, Ozaki K, Shoji S, Funatsu T: Integration in a multilayer microfluidic chip of 8 parallel cell sorters with flow control by sol-gel transition of thermoreversible gelation polymer. Lab Chip. 2010.10; 10 (19): 2559-2565. ( PubMed , DOI )

  15. Kudo H, Suzuki Y, Gessei T, Takahashi D, Arakawa T, Mitsubayashi K: Biochemical gas sensor (bio-sniffer) for ultrahigh-sensitive gaseous formaldehyde monitoring. Biosensors and Bioelectronics. 2010.10; 26 (2): 854-858. ( PubMed , DOI )

  16. Ogawa Y., Nonaka Y., Goto T., Ohnishi E., Hiramatsu T., Kii I., Yoshida M., Ikura T., Onogi H., Shibuya H., Hosoya T., Ito N., Hagiwara M.: Development of a novel selective inhibitor of the Downsyndrome-related kinase Dyrk1A. Nat. Commun.. 2010.10; ( PubMed , DOI )

  17. Yasuda K, Kaneko T, Nomura F: On-Chip Pre-Clinical Cardiac Toxicity: Testing Compounds Beyond hERG And QT Using hES/hiPS Cardiomyocyte Re-Entry Cell Network Model On a Chip. Proceeding of The 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences. 2010.10; 716-718.

  18. Ryuichi Mashima, Kazuho Honda, Yi Yang, Yohei Morita, Akane Inoue, Sumimasa Arimura, Hiroshi Nishina, Hideo Ema, Hiromitsu Nakauchi, Brian Seed, Hideaki Oda, Yuji Yamanashi: Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma. Lab. Invest.. 2010.09; 90 (9): 1357-1364. ( PubMed , DOI )

  19. Kohta R, Kotake Y, Hosoya T, Hiramatsu T, Otsubo Y, Koyama H, Hirokane Y, Yokoyama Y, Ikeshoji H, Oofusa K, Suzuki M, Ohta S: 1-Benzyl-1,2,3,4-tetrahydroisoquinoline binds with tubulin beta, a substrate of parkin, and reduces its polyubiquitination. J Neurochem. 2010.09; 114 (5): 1291-1301. ( PubMed , DOI )

  20. Kii I, Shiraishi A, Hiramatsu T, Matsushita T, Uekusa H, Yoshida S, Yamamoto M, Kudo A, Hagiwara M, Hosoya T: Strain-promoted double-click reaction for chemical modification of azido-biomolecules. Org Biomol Chem. 2010.09; 8 (18): 4051-4055. ( PubMed , DOI )

  21. Hayashi M, Yasuda K: Simple Microfluidic Continuous Concentration of Microparticles with Different Dielectric Constants Using Dielectrophoretic Force in a V-Shaped Electrode Array. Jpn J Appl Phys. 2010.09; 49 (9): 97002 1-5. ( DOI )

  22. Matsumura K, Yagi T, Hattori A, Soloviev M, Yasuda K: Using single cell cultivation system for on-chip monitoring of the interdivision timer in Chlamydomonas reinhardtii cell cycle. J Nanobiotechnology. 2010.09; 8 23. ( PubMed , DOI )

  23. Kataoka-Hamai C, Higuchi M, Iwai H, Miyahara Y: Detergent-Mediated Formation of Polymer-Supported Phospholipid Bilayers Langmuir. 2010.09; 26 (18): 14600-14605.

  24. Fortina P, Kricka LJ, Bonnell D, Kulkarni A, Wang J, Miyahara Y, Ure D: Nanotechnology: Improving Clinical Testing? Clin Chem. 2010.09; 56 (9): 1384-1389.

  25. Shinya Urano, Chinatsu Kaneko, Takahito Nei, Natsuki Motoi, Ryushi Tazawa, Masato Watanabe, Masahiro Tomita, Takahiro Adachi, Hiroko Kanazawa, Koh Nakata: A cell-free assay to estimate the neutralizing capacity of granulocyte-macrophage colony-stimulating factor autoantibodies. J. Immunol. Methods. 2010.08; 360 (1-2): 141-148. ( PubMed , DOI )

  26. Masaaki Ozawa,Shunsuke Kawamata,Tadahiro Etoh,Masahiko Hayashi,Kanki Komiyama,Akio Kishida,Chiaki Kuroda,Ayumi Ohsaki: Structures of New Erythrinan Alkaloids and Nitric Oxide Production Inhibitors from Erythrina crista-galli Chemical and Pharmaceutical Bulletin . 2010.08; 58 (8): 1119-1122. ( DOI )

  27. K.Oya,Y.Tanaka,Y.Moriyama,Y.Yoshioka,T.Kimura,Y.Tsutsumi,H.Doi,N.Nomura ,K.Noda,A.Kishida,T.Hanawa: Differences on the bone differentiation properties of MC3T3-E1 cells on polished buld and sputter-deposited titanium specimens Journal of Biomedical Materials Research Part A . 2010.08; 94A (2): 611-618. ( DOI )

  28. Yoshimura K, Harada S, Shibata J, Hatada M, Yamada Y, Ochiai C, Tamamura H, Matsushita S: Enhanced exposure of human immunodeficiency virus type 1 primary isolate neutralization epitopes through binding of CD4 mimetic compounds. J Virol. 2010.08; 84 (15): 7558-7568. ( PubMed , DOI )

  29. Wang X, Ando E, Takahashi D, Arakawa T, Kudo H, Saito H, Mitsubayashi K: 2D spatiotemporal visualization system of expired gaseous ethanol after oral administration for real-time illustrated analysis of alcohol metabolism. Talanta. 2010.08; 82 (3): 892-898. ( PubMed , DOI )

  30. Takeshi Maruyama, Hisae Kadowaki, Noriaki Okamoto, Atsushi Nagai, Isao Naguro, Atsushi Matsuzawa, Hiroshi Shibuya, Keiji Tanaka, Shigeo Murata, Kohsuke Takeda, Hideki Nishitoh, Hidenori Ichijo: CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response. EMBO J.. 2010.08; 29 (15): 2501-2514. ( PubMed , DOI )

  31. Kim H, Takei H, Yasuda K: Production of Nanoparticles Using Several Materials for Labeling of Biological Molecules. Jpn J Appl Phys. 2010.08; 49 (8): 87001 1-7. ( DOI )

  32. Yasuda K, Kaneko T, Nomura F: On-Chip Cellomics for Cardiotoxyty: Cell Network Model For Re-Construction of Higher Complexity of Organs. The Open Conference Proceedings Journal. 2010.08; 1 168-177. ( DOI )

  33. Matsumoto A, Cabral H, Sato N, Kataoka K, Miyahara Y: Assessment of tumor metastasis by the direct determination of cell-membrane sialic acid expression. Angew Chem Int Ed Engl. 2010.07; 49 (32): 5494-5497. ( PubMed , DOI )

  34. Tomoko Yoshida,Motohiro Komaki,Hideshi Hattori,Jun Negishi,Akio Kishida,Ikuo Morita,Mayumi Abe: Therapeutic Angiogenesis by Implantation of a Capillary Structure Constituted of Human Adipose Tissue Microvascular Endothelial Cells Arteriosclerosis, Thrombosis, and Vascular Biology . 2010.07; 30 (7): 1300-1306. ( DOI )

  35. Jungwon Seo, Yoichi Asaoka, Yoko Nagai, Jun Hirayama, Tokiwa Yamasaki, Misako Namae, Shinya Ohata, Nao Shimizu, Takahiro Negishi, Daiju Kitagawa, Hisato Kondoh, Makoto Furutani-Seiki, Josef M Penninger, Toshiaki Katada, Hiroshi Nishina: Negative regulation of wnt11 expression by Jnk signaling during zebrafish gastrulation. J. Cell. Biochem.. 2010.07; 110 (4): 1022-1037. ( PubMed , DOI )

  36. Toshihiko Matsumoto, Shuji Terai, Toshiyuki Oishi, Shinya Kuwashiro, Koichi Fujisawa, Naoki Yamamoto, Yusuke Fujita, Yoshihiko Hamamoto, Makoto Furutani-Seiki, Hiroshi Nishina, Isao Sakaida: Medaka as a model for human nonalcoholic steatohepatitis. Dis Model Mech. 2010.07; 3 (7-8): 431-440. ( PubMed , DOI )

  37. Masahiko Tanaka, Hideyuki Hara, Hiroshi Nishina, Kentaro Hanada, Ken'ichi Hagiwara, Tomohiko Maehama: An improved method for cell-to-cell transmission of infectious prion. Biochem. Biophys. Res. Commun.. 2010.07; 397 (3): 505-508. ( PubMed , DOI )

  38. Suzuki S, Urano E, Hashimoto C, Tsutsumi H, Nakahara T, Tanaka T, Nakanishi Y, Maddali K, Han Y, Hamatake M, Miyauchi K, Pommier Y, Beutler JA, Sugiura W, Fuji H, Hoshino T, Itotani K, Nomura W, Narumi T, Yamamoto N, Komano JA, Tamamura H: Peptide HIV-1 Integrase Inhibitors from HIV-1 Gene Products. J Med Chem. 2010.07; 53 (14): 5356-5360. ( PubMed , DOI )

  39. Suzuki S, Maddali K, Hashimoto C, Urano E, Ohashi N, Tanaka T, Ozaki T, Arai H, Tsutsumi H, Narumi T, Nomura W, Yamamoto N, Pommier Y, Komano JA, Tamamura H: Peptidic HIV integrase inhibitors derived from HIV gene products: Structure-activity relationship studies. Bioorg Med Chem. 2010.07; 18 6771-6775. ( PubMed , DOI )

  40. Inaba Yuka, Nakabayashi Makoto, Itoh Toshimasa, Yoshimoto Nobuko, Ikura Teikichi, Ito Nobutoshi, Shimizu Masato, Yamamoto Keiko: 22S-butyl-1alpha,24R-dihydroxyvitamin D3: recovery of vitamin D receptor agonistic activity. J Steroid Biochem Mol Biol. 2010.07; 121 (1-2): 146-150. ( PubMed , DOI )

  41. Yoko Nagai, Yoichi Asaoka, Misako Namae, Kota Saito, Haruka Momose, Hiroshi Mitani, Makoto Furutani-Seiki, Toshiaki Katada, Hiroshi Nishina: The LIM protein Ajuba is required for ciliogenesis and left-right axis determination in medaka. Biochem. Biophys. Res. Commun.. 2010.06; 396 (4): 887-893. ( PubMed , DOI )

  42. Melchionna R, Di Carlo A, De Mori R, Cappuzzello C, Barberi L, Musaro A, Cencioni C, Fujii N, Tamamura H, Crescenzi M, Capogrossi MC, Napolitano M, Germani A: Induction of myogenic differentiation by SDF-1 via CXCR4 and CXCR7 receptors. Muscle Nerve. 2010.06; 41 (6): 828-835. ( PubMed , DOI )

  43. Hattori A, Yasuda K: Comprehensive Study of Microgel Electrode for On-Chip Electrophoretic Cell Sorting. Jpn J Appl Phys. 2010.06; 49 (6): 06GM04 1-4. ( DOI )

  44. Terazono H, Takei H, Hattori A, Yasuda K: Development of a High-Speed Real-Time Polymerase Chain Reaction System Using a Circulating Water-Based Rapid Heat-Exchange. Jpn J Appl Phys. 2010.06; 49 (6): 06GM05 1-5. ( DOI )

  45. Kim H, Kira A, Yasuda K: Non-amplified Quantitative Detection of Nucleic Acid Sequences Using a Gold Nanoparticle Probe Set and Field-Emission Scanning Electron Microscopy. Jpn J Appl Phys. 2010.06; 49 (6): 06GK07 1-6. ( DOI )

  46. Kataoka-Hamai C, Miyahara Y: Field-effect detection using phospholipid membranes Science and Technology of Advanced Materials. 2010.06; 11 (3):

  47. Takahiro Kawashima,Tsuyoshi Kimura,Takayuki Shibata,Akio Kishida,Takashi Mineta,Eiji Makino: Feasibility study on cellular network analysis with patterned cell culture microdevice Microelectronic Engineering. 2010.05; 87 (5-8): 704-707. ( DOI )

  48. Ayako Katoh,Toru Masuzawa,Kazuhide Ozeki,Akio Kishida,Tsuyosh Kimura,Tetsuya Higami: Development of tissue adhension method using integrated low-level energies Medical Engineering & Physics . 2010.05; 32 (4): 304-311. ( DOI )

  49. Yoshihide Hashimoto, Seiichi Funamoto, Shuji Sasaki, Takako Honda, Shinya Hattori, Kwangwoo Nam, Tsuyoshi Kimura, Manabu Mochizuki, Toshiya Fujisato, Hisatoshi Kobayashi, Akio Kishida: Preparation and characterization of decellularized cornea using high-hydrostatic pressurization for corneal tissue engineering Biomaterials. 2010.05; 31 (14): 3941-3948. ( PubMed , DOI )

  50. Seiichi Funamoto, Kwangwoo Nam, Tsuyoshi Kimura, Ayako Murakoshi, Yoshihide Hashimoto, Kazuo Niwaya, Soichiro Kitamura, Toshiya Fujisato, Akio Kishida: The use of high-hydrostatic pressure treatment to decellularize blood vessels Biomaterials. 2010.05; 31 (13): 3590-3595. ( PubMed , DOI )

  51. Terazono H, Takei H, Hayashi M, Hattori A, Yasuda K: Development of an integrated system for rapid detection of biological agents. Proceeding of SPIE Defense, Security, and Sensing 2010. 2010.05; 766503 766503. ( DOI )

  52. Bonanni A, Pumera M, Miyahara Y: Rapid, Sensitive, and Label-Free Impedimetric Detection of a Single-Nucleotide Polymorphism Correlated to Kidney Disease Anal Chem. 2010.05; 82 (9): 3772-3779.

  53. Matsumoto A, Yamamoto K, Yoshida R, Kataoka K, Aoyagi T, Miyahara Y: A totally synthetic glucose responsive gel operating in physiological aqueous conditions. Chem Commun (Camb). 2010.04; 46 (13): 2203-2205. ( PubMed , DOI )

  54. Shimizu S, Konishi A, Nishida Y, Mizuta T, Nishina H, Yamamoto A, Tsujimoto Y: Involvement of JNK in the regulation of autophagic cell death. Oncogene. 2010.04; 29 (14): 2070-2082. ( PubMed , DOI )

  55. Kentaro Nakagawa, Misato Sugahara, Tokiwa Yamasaki, Hiroaki Kajiho, Shinya Takahashi, Jun Hirayama, Yasuhiro Minami, Yasutaka Ohta, Toshio Watanabe, Yutaka Hata, Toshiaki Katada, Hiroshi Nishina: Filamin associates with stress signalling kinases MKK7 and MKK4 and regulates JNK activation. Biochem. J.. 2010.04; 427 (2): 237-245. ( PubMed , DOI )

  56. Xin WANG, Eri ANDO, Daishi TAKAHASHI, Takahiro ARAKAWA, Hiroyuki KUDO, Hirokazu SAITO and Kohji MITSUBAYASHI: 2-D spatiotemporal visualization system of expired gaseous ethanol after oral administration for real-time illustrated analysis of alcohol metabolism. Talanta. 2010.04; 82 (3): 892-898.

  57. Kato R, Munkhjargal M, Takahashi D, Arakawa T, Kudo H, Mitsubayashi K.: An autonomous drug release system based on chemo-mechanical energy conversion Organic Engine for feedback control of blood glucose. Biosensors and Bioelectronics. 2010.04; 26 (4): 1455-1459.

  58. Tomoyuki Koshidaa, Takahiro Arakawab, Tomoko Gesseib,c, Daishi Takahashib, Hiroyuki Kudob, Hirokazu Saitod, Kazuyoshi Yanoa, Kohji Mitsubayashi: Fluorescence biosensing system with a UV-LED excitation for l-leucine detection Sensors and Actuators B: Chemical. 2010.04; 146 (1): 177-182.

  59. Koshida T, Arakawa T, Gessei T, Takahashi D, Kudo H, Saito H, Yano K, Mitsubayashi K: Fluorescence biosensing system with a UV-LED excitation for L-leucine detection. Sensors and Actuators B: Chemical. 2010.04; 146 177-182. ( DOI )

  60. Nakahara T, Nomura W, Ohba K, Ohya A, Tanaka T, Hashimoto C, Narumi T, Murakami T, Yamamoto N, Tamamura H: Remodeling of dynamic structures of HIV-1 envelope proteins leads to synthetic antigen molecules inducing neutralizing antibodies. Bioconjug Chem. 2010.04; 21 (4): 709-714. ( PubMed , DOI )

  61. Iguchi S, Chu MX, Takahashi D, Arakawa T, Kudo H, Mitsubayashi K: Soft-MEMS Glucose Sensor with Functional Polymers. Journal of Photopolymer Science and Technology. 2010.04; 23 (2): 167-170.

  62. Kudo H, Sawai M, Suzuki Y, Wang X, Gessei T, Takahashi D, Arakawa T, Mitsubayashi K: Fiber optic bio-sniffer (biochemical gas sensor) for high selective monitoring of ethanol vapor using 335 nm UV-LED. Sensors and Actuators B: Chemical. 2010.04; 147 676-680. ( DOI )

  63. Aoki T, Shimizu S, Urano E, Futahashi Y, Hamatake M, Tamamura H, Terashima K, Murakami T, Yamamoto N, Komano J: Improvement of lentiviral vector-mediated gene transduction by genetic engineering of the structural protein Pr55(Gag). Gene Ther. 2010.04; 17 (9): 1124-1133. ( PubMed , DOI )

  64. Ozaki K, H. Sugino, Y. Shirasaki, T. Aoki, T. Arakawa T. Funatsu, S. Shoji: Microfluidic cell sorter with flow switching triggered by a sol-gel transition of a thermo-reversible gelation polymer. Sensors and Actuators B: Chemical. 2010.04; 150 449-455. ( DOI )

  65. Yoon DH, Bahk YK, Kwon BH, Kim SS, Kim YD, Arakawa T, Go JS, Shoji S: Improvement of Filtration Performance Using Self-Tuning of Flow Resistance. Jpn J Appl Phys. 2010.04; 50 (1): 017201-017201-6. ( DOI )

  66. Akira Nifuji, Hisashi Ideno, Yoshio Ohyama, Rieko Takanabe, Ryoko Araki, Masumi Abe, Masaki Noda, Hiroshi Shibuya: Nemo-like kinase (NLK) expression in osteoblastic cells and suppression of osteoblastic differentiation. Exp. Cell Res.. 2010.04; 316 (7): 1127-1136. ( PubMed , DOI )

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  68. Kim H, Negishi T, Kudo M, Takei H, Yasuda K: Quantitative backscattered electron imaging of field emission scanning electron microscopy for discrimination of nano-scale elements with nm-order spatial resolution. J Electron Microsc (Tokyo). 2010.04; 59 (5): 379-385. ( PubMed , DOI )

  69. Kim H, Takei H, Yasuda K: Production of Size-Controlled Nanoscopic Cap-Shaped Metal Shells. Jpn J Appl Phys. 2010.04; 49 (4): 48004 1-2. ( DOI )

  70. Terazono H, Takei H, Hattori A, Yasuda K: Development of a high-speed real-time PCR system for rapid and precise nucleotide recognition. Proceeding of SPIE Defense, Security, and Sensing 2010. 2010.04; 7673 76730U. ( DOI )

  71. Ishiura N, Nakashima H, Watanabe R, Kuwano Y, Adachi T, Takahashi Y, Tsubata T, Okochi H, Tamaki K, Tedder TF, Fujimoto M: Differential phosphorylation of functional tyrosines in CD19 modulates B-lymphocyte activation. Eur J Immunol. 2010.04; 40 (4): 1192-1204. ( PubMed , DOI )

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  73. Takahiro Negishi, Yoko Nagai, Yoichi Asaoka, Mami Ohno, Misako Namae, Hiroshi Mitani, Takashi Sasaki, Nobuyoshi Shimizu, Shuji Terai, Isao Sakaida, Hisato Kondoh, Toshiaki Katada, Makoto Furutani-Seiki, Hiroshi Nishina: Retinoic acid signaling positively regulates liver specification by inducing wnt2bb gene expression in medaka. Hepatology. 2010.03; 51 (3): 1037-1045. ( PubMed , DOI )

  74. Goda T, Miyahara Y: Detection of Microenvironmental Changes Induced by Protein Adsorption onto Self-Assembled Monolayers using an Extended Gate-Field Effect Transistor Anal Chem. 2010.03; 82 (5): 1803-1810.

  75. Kwangwoo Nam,Tsuyoshi Kimura,Seiichi Funamoto,Akio Kishida: Preparation of a collagen/polymer hybrid gel designed for tissue membranes. Part I:Controlling the polymer.collagen cross-linking process using an ethanol/water co-solvent Acta Biomaterialia . 2010.02; 6 (2): 403-408. ( DOI )

  76. Kwangwoo Nam,Tsuyoshi Kimura,Seiichi Funamoto,Akio Kishida: Preparation of a collagen/polymer hybrid gel for tissue membranes. Part II:In vitro and in vivo biological properties of the collagen gels Acta Biomaterialia . 2010.02; 6 (2): 409-417. ( DOI )

  77. Chiaki Yoshikawa, Yoshihide Hashimoto, Shinya Hattori, Takako Honda, Kun Zhang, Dohiko Terada, Akio Kishida, Yoshinobu Tsujii, Hisatoshi Kobayashi: Suppression of cell adhesion on well-defined concentrated polymer brushes of hydrophilic polymer Chem Lett. 2010.02; 39 (2): 142-143. ( DOI )

  78. Iguchi S, Chu MX, Takahashi D, Arakawa T, Kudo H, Mitsubayashi K.: Soft-MEMS glucose sensor with functional polymers. Journal of Photopolymer Science and Technology. 2010.02; 23 (2): 167-170.

  79. Kudo H, Suzuki Y, Gessei T, Takahashi D, Arakawa T, Mitsubayashi K.: Biochemical gas sensor (bio-sniffer) for ultrahigh-sensitive gaseous formaldehyde monitoring. Biosensors and Bioelectronics. 2010.02; 26 (2): 845-858.

  80. Hiroyuki Kudo, Masayuki Sawai, Yuki Suzuk , Xin Wang, Tomoko Gessei, Daishi Takahashi, Takahiro Arakawa, Kohji Mitsubayashi: Fiber optic bio-sniffer (biochemical gas sensor) for high selective monitoring of ethanol vapor using 335nm UV-LED. (306E20) Sensors and Actuators B: Chemical. 2010.02; 147 (2): 676-680.

  81. Eriko Ohnishi, Toshiyasu Goto, Atsushi Sato, Mi-Sun Kim, Shun-Ichiro Iemura, Tohru Ishitani, Tohru Natsume, Junji Ohnishi, Hiroshi Shibuya: Nemo-like kinase, an essential effector of anterior formation, functions downstream of p38 mitogen-activated protein kinase. Mol. Cell. Biol.. 2010.02; 30 (3): 675-683. ( PubMed , DOI )

  82. Amo R, Aizawa H, Takahoko M, Kobayashi M, Takahashi R, Aoki T, Okamoto H: Identification of the zebrafish ventral habenula as a homolog of the mammalian lateral habenula. J Neurosci. 2010.01; 30 (4): 1566-1574. ( PubMed , DOI )

  83. Arakawa T, Wang X, Ando E, Endo H, Takahashi D, Kudo H, Saito H, Mitsubayashi K.: Real-time chemiluminescence visualization system of spacially-distributed exhausted ethanol breath on enzyme immobilized mesh substrate. Luminescence. 2010.01; 25 185-187.

  84. Koshida T, Arakawa T, Gessei T, Takahashi D, Kudo H, Saito H, Yano K, Mitsubayashi K.: Fluorescence biosensing system with a UV-LED excitation for l-leucine detection. Sensors and Actuators B. 2010.01; 146 (1): 177-182.

  85. Yamada Y, Ochiai C, Yoshimura K, Tanaka T, Ohashi N, Narumi T, Nomura W, Harada S, Matsushita S, Tamamura H: CD4 mimics targeting the mechanism of HIV entry. Bioorg Med Chem Lett. 2010.01; 20 (1): 354-358. ( PubMed , DOI )

  86. Yukihide Watanabe, Susumu Itoh, Toshiyasu Goto, Eriko Ohnishi, Masako Inamitsu, Fumiko Itoh, Kiyotoshi Satoh, Eliza Wiercinska, Weiwen Yang, Liang Shi, Aya Tanaka, Naoko Nakano, A Mieke Mommaas, Hiroshi Shibuya, Peter Ten Dijke, Mitsuyasu Kato: TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling. Mol. Cell. 2010.01; 37 (1): 123-134. ( PubMed , DOI )

  87. Ito S, Takechi S, Nakahara K, Kashige N, and Yamaguchi T: Phenyl-Substituted Dihydropyrazines with DNA Strand-Breakage Activity. Chemical & Pharmaceutical Bulletin. 2010; 58 (6): 825-828.

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  94. Kataoka-Hamai C, Miyahara Y: Mechanisms of supported bilayer detection using field-effect devices Analyst. 2010; 135 (1): 189-194.

  95. Matsumoto A, Cabral H, Sato N, Kataoka K, Miyahara Y: Assessment of Tumor Metastasis by the Direct Determination of Cell-Membrane Sialic Acid Expression Angew Chem Int Edit. 2010; 49 (32): 5494-5497.

  96. Matsumoto A, Yamamoto K, Yoshida R, Kataoka K, Aoyagi T, Miyahara Y: A totally synthetic glucose responsive gel operating in physiological aqueous conditions Chem Commun. 2010; 46 (13): 2203-2205.

  1. Ayumi Ohsaki,Takashi Nagaoka,Kaisuke Yoneda,Akio Kishida: Secu’amamines E–G, new alkaloids from Securinega suffruticosa var. amamiensis Tetrahedron Letters. 2009.12; 50 (50): 6965-6967. ( DOI )

  2. Ryota Saito, Tokiwa Yamasaki, Yoko Nagai, Jinzhan Wu, Hiroaki Kajiho, Tadashi Yokoi, Eiichiro Noda, Sachiko Nishina, Hitoshi Niwa, Noriyuki Azuma, Toshiaki Katada, Hiroshi Nishina: CrxOS maintains the self-renewal capacity of murine embryonic stem cells. Biochem. Biophys. Res. Commun.. 2009.12; 390 (4): 1129-1135. ( PubMed , DOI )

  3. Islam MS, Yoshida H, Matsuki N, Ono K, Nagasaka R, Ushio H, Guo Y, Hiramatsu T, Hosoya T, Murata T, Hori M, Ozaki H: Antioxidant, free radical-scavenging, and NF-kappaB-inhibitory activities of phytosteryl ferulates: structure-activity studies. J Pharmacol Sci. 2009.12; 111 (4): 328-337. ( PubMed )

  4. Ikemoto T, Hosoya T, Takata K, Aoyama H, Hiramatsu T, Onoe H, Suzuki M, Endo M: Functional role of neuroendocrine-specific protein-like 1 in membrane translocation of GLUT4. Diabetes. 2009.12; 58 (12): 2802-2812. ( PubMed , DOI )

  5. Ihara M, Sakata T, Makino I, Miyahara Y, Ueda H: Open sandwich-based immuno-transistor for label-free and highly sensitive detection of low molecular weight antigens J Biosci Bioeng. 2009.11; 108 S158.

  6. Matsumoto A, Sato N, Sakata T, Yoshida R, Kataoka K, Miyahara Y: Chemical-to-Electrical-Signal Transduction Synchronized with Smart Gel Volume Phase Transition Adv Mater. 2009.11; 21 (43): 4372-+.

  7. Pumera M, Miyahara Y: What amount of metallic impurities in carbon nanotubes is small enough not to dominate their redox properties? Nanoscale. 2009.11; 1 (2): 260-265.

  8. Akira Matsumoto, Naoko Sato, Toshiya Sakata, Ryo Yoshida, Kazunori Kataoka, Yuji Miyahara: Chemical-to-Electrical-Signal Transduction Synchronized with Smart Gel Volume Phase Transition ADVANCED MATERIALS. 2009.11; 21 (43): 4372-+. ( DOI )

  9. Suzuki M, Sumi K, Koyama H, Siqin, Hosoya T, Takashima-Hirano M, Doi H: Pd(0)-Mediated rapid coupling between methyl iodide and heteroarylstannanes: an efficient and general method for the incorporation of a positron-emitting (11)C radionuclide into heteroaromatic frameworks. Chem Eur J. 2009.11; 15 (45): 12489-12495. ( PubMed , DOI )

  10. Matsumoto A, Endo T, Yoshida R, Miyahara Y: Electrical visualization of chemo-mechanical signal transduction using a smart gel-modified gate field effect transistor. Chem Commun (Camb). 2009.10; (37): 5609-5611. ( PubMed , DOI )

  11. Shuji Sasaki,Seiichi Funamoto,Yoshihide Hashimoto,Tsuyoshi Kimura,Takako Honda,Shinya Hattori ,Hisatoshi Kobayashi,Akio Kishida,Manabu Mochizuki: In vivo evaluation of a novel scaffold for artificial corneas prepared by using ultrahigh hydrostatic pressure to decellularize porcine corneas Molecular Vision. 2009.10; 15 2022-2028.

  12. Akira Matsumoto, Naoko Sato, Horacio Cabral, Kazunori Kataoka, Yuji Miyahara: Label Free Potentiometric Sialic Acid Detection Applicable to Living Cell Diagnosis IEEE Sensors 2009. 2009.10;

  13. Shuji Sasaki, Seiichi Funamoto, Yoshihide Hashimoto, Tsuyoshi Kimura, Takako Honda, Shinya Hattori, Hisatoshi Kobayashi, Akio Kishida, Manabu Mochizuki: In vivo evaluation of a novel scaffold for artificial corneas prepared by using ultrahigh hydrostatic pressure to decellularize porcine corneas Mol Vis. 2009.10; 15 2022-2028. ( PubMed )

  14. Yoko Miyoshia, Kumiko Miyajimab, Hirokazu Saitoc, Hiroyuki Kudob, Toshifumi Takeuchid, Isao Karubee, Kohji Mitsubayashi: Flexible humidity sensor in a sandwich configuration with a hydrophilic porous membrane. Sensors and Actuators B: Chemical. 2009.10; 142 (1): 28-32.

  15. Pumera Martin, Scipioni Roberto, Iwai Hideo, Ohno Takahisa, Miyahara Yuji, Boero Mauro: A mechanism of adsorption of beta-nicotinamide adenine dinucleotide on graphene sheets: experiment and theory. Chemistry. 2009.10; 15 (41): 10851-10856. ( PubMed , DOI )

  16. Pumera Martin, Iwai Hideo, Miyahara Yuji: Germanium-oxide-coated carbon nanotubes. Nanotechnology. 2009.10; 20 (42): 425606. ( PubMed , DOI )

  17. Pumera M, Iwai H, Miyahara Y: Germanium-oxide-coated carbon nanotubes Nanotechnology. 2009.10; 20 (42):

  18. Ohashi N, Nomura W, Kato M, Narumi T, Lewin NE, Blumberg PM, Tamamura H: Synthesis of protein kinase Cdelta C1b domain by native chemical ligation methodology and characterization of its folding and ligand binding. J Pept Sci. 2009.10; 15 (10): 642-646. ( PubMed , DOI )

  19. Kim H, Takei H, Yasuda K: Quantitative evaluation of nano-particle-based labeling at a measurement of DNA microarray. Sensors and Actuators B: Chemical. 2009.10; 144 (1): 6-10. ( DOI )

  20. Matsumoto A, Sato N, Kataoka K, Miyahara Y: Noninvasive sialic acid detection at cell membrane by using phenylboronic acid modified self-assembled monolayer gold electrode. J Am Chem Soc. 2009.09; 131 (34): 12022-12023. ( PubMed , DOI )

  21. Tsuyoshi Kimura,Hokuto Konno,Toshiya Fujisato,Akio Kishida: Expression behavior of high-pressure-compacted　plasmid DNA in mammalian cell Nucleic Acids Symposium Series. 2009.09; 53 (1): 313-314. ( DOI )

  22. Jun Hirayama, Norio Miyamura, Yoshimi Uchida, Yoichi Asaoka, Reiko Honda, Kenji Sawanobori, Takeshi Todo, Takuro Yamamoto, Paolo Sassone-Corsi, Hiroshi Nishina: Common light signaling pathways controlling DNA repair and circadian clock entrainment in zebrafish. Cell Cycle. 2009.09; 8 (17): 2794-2801. ( PubMed )

  23. Tanaka T, Nomura W, Narumi T, Esaka A, Oishi S, Ohashi N, Itotani K, Evans BJ, Wang ZX, Peiper SC, Fujii N, Tamamura H: Structure-activity relationship study on artificial CXCR4 ligands possessing the cyclic pentapeptide scaffold: the exploration of amino acid residues of pentapeptides by substitutions of several aromatic amino acids. Org Biomol Chem. 2009.09; 7 (18): 3805-3809. ( PubMed , DOI )

  24. Matsumoto A, Sato N, Kataoka K, Miyahara Y: Noninvasive Sialic Acid Detection at Cell Membrane by Using Phenylboronic Acid Modified Self-Assembled Monolayer Gold Electrode J Am Chem Soc. 2009.09; 131 (34): 12022-+.

  25. Inouye S, Hosoya T: Reconstitution of blue fluorescent protein from recombinant apoaequorin and synthetic coelenteramide. Biochem Biophys Res Commun. 2009.09; 386 (4): 617-622. ( PubMed , DOI )

  26. Sakata T, Ihara M, Makino I, Miyahara Y, Ueda H: Open Sandwich-Based Immuno-Transistor for Label-Free and Noncompetitive Detection of Low Molecular Weight Antigen Anal Chem. 2009.09; 81 (18): 7532-7537.

  27. Pumera M, Iwai H, Miyahara Y: Bimetallic Nickel-Iron Impurities within Single-Walled Carbon Nanotubes Exhibit Redox Activity towards the Oxidation of Amino Acids Chemphyschem. 2009.08; 10 (11): 1770-1773.

  28. Kim H. Yasuda K. Takei H.: Production of nanoscopic metal labels for electron microscopy: Specific detection of target DNA. Sensors and Actuators B: Chemical. 2009.08; 142 (1): 1-6. ( DOI )

  29. Norio Miyamura, Jun Hirayama, Kenji Sawanobori, Teruya Tamaru, Yoichi Asaoka, Reiko Honda, Takuro Yamamoto, Hatsume Uno, Ken Takamatsu, Hiroshi Nishina: CLOCK:BMAL-independent circadian oscillation of zebrafish Cryptochrome1a gene. Biol. Pharm. Bull.. 2009.07; 32 (7): 1183-1187. ( PubMed )

  30. Takashi Nakamura, Hiroshi Nishina: Liver development: lessons from knockout mice and mutant fish. Hepatol. Res.. 2009.07; 39 (7): 633-644. ( PubMed , DOI )

  31. Matsumoto A, Sato N, Miyahara Y: Label free carbohydrate detection by using phenylboronic acid gate-modified field effect transistor Current Applied Physics. 2009.07; 9 (4): E214-E217.

  32. A. Matsumoto, N. Sato, Y. Miyahara: Label free carbohydrate detection by using phenylboronic acid gate-modified field effect transistor CURRENT APPLIED PHYSICS. 2009.07; 9 (4): E214-E217. ( DOI )

  33. Shimamoto Y, Suzuki M, Mikhailenko SV, Yasuda K, Ishiwata S: Inter-sarcomere coordination in muscle revealed through individual sarcomere response to quick stretch. Proc Natl Acad Sci USA. 2009.07; 106 (29): 11954-11959. ( PubMed , DOI )

  34. Sakata T, Miyahara Y: Charged nanosphere-coupled biotransistor for highly sensitive genetic analysis Current Applied Physics. 2009.07; 9 (4): E210-E213.

  35. Nao Shimizu, Hajime Watanabe, Junko Kubota, Jinzhan Wu, Ryota Saito, Tadashi Yokoi, Takumi Era, Takeshi Iwatsubo, Takashi Watanabe, Sachiko Nishina, Noriyuki Azuma, Toshiaki Katada, Hiroshi Nishina: Pax6-5a promotes neuronal differentiation of murine embryonic stem cells. Biol. Pharm. Bull.. 2009.06; 32 (6): 999-1003. ( PubMed )

  36. Kira A. Kim H. Yasuda K.: Homogeneous Immobilization of Probe DNAs on DNA Chip Using Polyurea Thin Film. e-Journal of Surface Science and Nanotechnology. 2009.06; 7 728-730. ( DOI )

  37. Aoki K, Sato N, Yamaguchi A, Kaminuma O, Hosozawa T, Miyatake S: Regulation of DNA demethylation during maturation of CD4+ naive T cells by the conserved noncoding sequence 1. J Immunol. 2009.06; 182 (12): 7698-7707. ( PubMed , DOI )

  38. Tanaka T, Tohyama S, Murata M, Nomura F, Kaneko T, Chen H, Hattori F, Egashira T, Seki T, Ohno Y, Koshimizu U, Yuasa S, Ogawa S, Yamanaka S, Yasuda K, Fukuda K: In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes. Biochem Biophys Res Commun. 2009.05; 385 (4): 497-502. ( PubMed , DOI )

  39. MingXing CHU1, Hiroyuki KUDO2, Takayuki SHIRAI3, Kumiko MIYAJIMA2, Hirokazu SAITO2, Nobuyuki MORIMOTO4, Kazuyoshi YANO5, Yasuhiko IWASAKI6, Kazunari AKIYOSHI4, Kohji MITSUBAYASHI: A soft and flexible biosensor using a phospholipid polymer for continuous glucose monitoring. Biomedical microdevices. 2009.04; 11 (4): 837-842.

  40. Sugino H, Ozaki K, Shirasaki Y, Arakawa T, Shoji S, Funatsu T: On-chip microfluidic sorting with fluorescence spectrum detection and multiway separation. Lab Chip. 2009.04; 9 1254-1260. ( DOI )

  41. Yamaguchi Y, Arakawa T, Takeda N, Edagawa Y, Shoji S: Development of a poly-dimethylsiloxane microfluidic device for single cell isolation and incubation. Sensors and Actuators B: Chemical. 2009.04; 136 (2): 555-561. ( DOI )

  42. Soma M, Aizawa H, Ito Y, Maekawa M, Osumi N, Nakahira E, Okamoto H, Tanaka K, Yuasa S: Development of the mouse amygdala as revealed by enhanced green fluorescent protein gene transfer by means of in utero electroporation. J Comp Neurol. 2009.03; 513 (1): 113-128. ( PubMed , DOI )

  43. Y.Sawa、E.Tatsumi、A.Funakubo、T.Horiuchi、K.Iwasaki、A.Kishida、T.Masuzawa、K.Matsuda、M.Nishimura、T.Nishimura、Y.Tomizawa、T.Yamaoka、H.Watanabe: Journal of Artificial Organs 2008:the year in review J. Artif Organs. 2009.03; 12 (1): 1-7.

  44. Kwangwoo Nam,Ayako Murakoshi,Tsuyoshi Kimura,Toshiya Fujisato,Soichiro Kitamura,Akio Kishida: Study on the physical properties of tissue-engineered blood vessels made by chemical cross-linking and polymer-tissue cross-linking Journal of Artificial Organs. 2009.03; 12 (1): 47-54. ( DOI )

  45. Shuhei Tanemura, Haruka Momose, Nao Shimizu, Daiju Kitagawa, Jungwon Seo, Tokiwa Yamasaki, Kentaro Nakagawa, Hiroaki Kajiho, Josef M Penninger, Toshiaki Katada, Hiroshi Nishina: Blockage by SP600125 of Fcepsilon receptor-induced degranulation and cytokine gene expression in mast cells is mediated through inhibition of phosphatidylinositol 3-kinase signalling pathway. J. Biochem.. 2009.03; 145 (3): 345-354. ( PubMed , DOI )

  46. Gessei T, Sato H, Kazawa E, Kudo H, Saito H, Mitsubayashi K.: Bio-sniffers for ethanol and acetaldehyde using carbon and Ag/AgCl coated electrodes. Microchim Acta.. 2009.03; 165 179-186.

  47. Hulme JP, An SSA, Goddard N, Miyahara Y, Oki A: Fabrication of a flexible multi-referenced surface plasmon sensor using room temperature nanoimprint lithography Current Applied Physics. 2009.03; 9 (2): E185-E188.

  48. Hosoya T, Inoue A, Hiramatsu T, Aoyama H, Ikemoto T, Suzuki M: Facile synthesis of diazido-functionalized biaryl compounds as radioisotope-free photoaffinity probes by Suzuki-Miyaura coupling. Bioorg Med Chem. 2009.03; 17 (6): 2490-2496. ( PubMed , DOI )

  49. Shinya Ohata, Makiko Nawa, Takeshi Kasama, Tokiwa Yamasaki, Kenji Sawanobori, Shoji Hata, Takashi Nakamura, Yoichi Asaoka, Toshio Watanabe, Hitoshi Okamoto, Takahiko Hara, Shuji Terai, Isao Sakaida, Toshiaki Katada, Hiroshi Nishina: Hematopoiesis-dependent expression of CD44 in murine hepatic progenitor cells. Biochem. Biophys. Res. Commun.. 2009.02; 379 (4): 817-823. ( PubMed , DOI )

  50. Kuramori C, Azuma M, Kume K, Kaneko Y, Inoue A, Yamaguchi Y, Kabe Y, Hosoya T, Kizaki M, Suematsu M, Handa H: Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus. Biochem Biophys Res Commun. 2009.02; 379 (2): 519-525. ( PubMed , DOI )

  51. Inaba Y, Yoshimoto N, Sakamaki Y, Nakabayashi M, Ikura T, Tamamura H, Ito N, Shimizu M, Yamamoto K: A New Class of Vitamin D Analogues that Induce Structural Rearrangement of the Ligand-Binding Pocket of the Receptor. J Med Chem. 2009.02; ( PubMed , DOI )

  52. Toda M, Hisano R, Yurugi H, Akita K, Maruyama K, Inoue M, Adachi T, Tsubata T, Nakada H: Ligation of tumour-produced mucins to CD22 dramatically impairs splenic marginal zone B-cells. Biochem J. 2009.02; 417 (3): 673-683. ( PubMed , DOI )

  53. Hou R, Ohtsuji M, Ohtsuji N, Zhang L, Adachi T, Hirose S, Tsubata T: Centromeric interval of chromosome 4 derived from C57BL/6 mice accelerates type 1 diabetes in NOD.CD72b congenic mice. Biochem Biophys Res Commun. 2009.02; 380 (1): 193-197. ( PubMed , DOI )

  54. Ozawa M,Komiyama K,Nakai I,Kishida A,Oosaki A: TRAIL-enhancing activity of Erythrinan alkaloids from Erythrina velutina Bioorganic & Medicinal Chemistry Letters. 2009.01; 19 (1): 234-236. ( DOI )

  55. Koji Futamura, Akira Matsumoto, Toshiya Sakata, Kazuhiko Ishihara, Yuji Miyahara: Phospholipid Polymer-modified Field Effect Transistor for Sensitive Detection of Biomolecular Recognition Proceedings of conference, MicroTAS 2009. 2009.01;

  56. Kudo H, Sawai M, Wang X, Gessei T, Koshida T, Miyajima K, Saito H, Mitsubayashi K.: A NADH-dependent fiber-optic biosensor for ethanol determination with a UV-LED excitation system. Sens. Actuator B-Chem. 2009.01; 141 20-25.

  57. Mitsubayashi K, Ohgoshi T, Okamoto T, Wakabayashi Y, Kozuka M, Miyajima K, Saito H, Kudo H: Tonometric biosensor with a differential pressure sensor for chemo-mechanical measurement of glucose. Biosens Bioelectron. 2009.01; 24 (5): 1518-1521. ( PubMed , DOI )

  58. Matsumoto A, Sato N, Sakata T, Kataoka K, Miyahara Y: Glucose-sensitive field effect transistor using totally synthetic compounds J Solid State Electr. 2009.01; 13 (1): 165-170.

  59. Yoon DH, Ha JB, Bahk YK, Arakawa T, Shoji S, Go JS: Size-selective separation of micro beads by utilizing secondary flow in a curved rectangular microchannel. Lab Chip. 2009.01; 9 (1): 87-90. ( PubMed , DOI )

  60. Akira Matsumoto, Naoko Sato, Toshiya Sakata, Kazunori Kataoka, Yuji Miyahara: Glucose-sensitive field effect transistor using totally synthetic compounds JOURNAL OF SOLID STATE ELECTROCHEMISTRY. 2009.01; 13 (1): 165-170. ( DOI )

  61. Kira A, Kim H, Yasuda K: Contribution of nanoscale curvature to number density of immobilized DNA on gold nanoparticles. Langmuir. 2009.01; 25 (3): 1285-1288. ( PubMed , DOI )

  62. Akira Matsumoto, Naoko Sato, Horacio Cabral, Kazunori Kataoka, Yuji Miyahara: Label Free Living Cell Diagnosis by Using Sialic Acid Selective Solid-state Electrode Proceedings of conference, MicroTAS 2009. 2009.01;

  63. Mizukoshi F, Baba K, Goto-Koshino Y, Setoguchi-Mukai A, Fujino Y, Ohno K, Tamamura H, Oishi S, Fujii N, Tsujimoto H: Inhibitory effect of newly developed CXC-chemokine receptor 4 antagonists on the infection with feline immunodeficiency virus. J Vet Med Sci. 2009.01; 71 (1): 121-124. ( PubMed )

  64. Murakami Y, Ishii H, Hoshina S, Takada N, Ueki A, Tanaka S, Kadoma Y, Ito S, Machino M, Fujisawa S: Antioxidant and Cyclooxygenase-2-inhibiting activity of 4,4'-biphenol, 2,2'-biphenol and phenol. Anticancer Res. 2009; 29 2403-2410.

  65. Kadoma Y, Ito S, Atsumi T, Fujisawa S,: Mechanisms of cytotoxicity of 2- or 2,6-di-tert-butylphenols and 2-methoxyphenols in terms of inhibition rate constant and a theoretical parameter. Chemosphere. 2009; 74 626-632.

  66. Gurbuz I, Yesilada E, Ito S: An anti-ulcerogenic flavonol diglucoside from Equisetum palustre L. Journal of Ethnopharmacology. 2009; 121 360-365.

  67. Akira Matsumoto, N. Sato, T. Sakata, R. Yoshida, K. Kataoka, Y. Miyahara: Electrical Signal Transduction Synchronized with Smart Gel Volume Phase Transition. Adv. Mater.. 2009; 21 4372-4378.

  68. Akira Matsumoto; Naoko Sato; Yuji Miyahara: Label Free Carbohydrate Detection By Using Phenylboronic Acid Gate-Modified Field Effect Transistor. Curr. Appl. Phys.. 2009; 9 214-217.

  69. Yoshifumi Matsumoto, Hiroki Oota, Yoichi Asaoka, Hiroshi Nishina, Koji Watanabe, Janusz M Bujnicki, Shoji Oda, Shoji Kawamura, Hiroshi Mitani: Medaka: a promising model animal for comparative population genomics. BMC Res Notes. 2009; 2 88. ( PubMed , DOI )

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  71. Tsutsumi H, Nomura W, Abe S, Mino T, Masuda A, Ohashi N, Tanaka T, Ohba K, Yamamoto N, Akiyoshi K, Tamamura H: Fluorogenically active leucine zipper peptides as tag-probe pairs for protein imaging in living cells. Angew Chem Int Ed Engl. 2009; 48 (48): 9164-9166. ( PubMed , DOI )

  72. Doi H, Ban I, Nonoyama A, Sumi K, Kuang C, Hosoya T, Tsukada H, Suzuki M: Palladium(0)-mediated rapid methylation and fluoromethylation on carbon frameworks by reacting methyl and fluoromethyl iodide with aryl and alkenyl boronic acid esters: useful for the synthesis of [11C]CH(3)--C- and [18F]FCH2--C-Containing PET tracers (PET=positron emission tomography). Chem Eur J. 2009; 15 (16): 4165-4171. ( PubMed , DOI )

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  74. Tamamura H, Tanaka T, Tsutsumi H, Ohashi N, Hiramatsu K, Araki T, Ojida A, Hamachi I, Wang Z, Peiper SC, Trent JO, Ueda S, Oishi S, Fujii N: Development of chemokine receptor CXCR4 antagonists using bio-mimetic strategy. Adv Exp Med Biol. 2009; 611 145-146. ( PubMed )

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  76. Tamamura H, Tanaka T, Tsutsumi H, Nemoto K, Mizokami S, Ohashi N, Oishi S, Fujii N: Stereoselective synthesis of peptidomimetics based on acid-catalyzed ring-opening of beta-aziridinyl-alpha,beta-enoates. Adv Exp Med Biol. 2009; 611 149-150. ( PubMed )

  1. Kwangoo NＡM、Tsuyoshi Kimura、Akio Kishida: Controlling coupling reaction of EDC and NHS for preparation of collagen gels using ethanol/water co-solvents Annual Reports of the Institute of Biomaterials and Bioengineering. 2008.12; 42 12-16.

  2. Tomohiko Maehama, Masahiko Tanaka, Hiroshi Nishina, Makoto Murakami, Yasunori Kanaho, Kentaro Hanada: RalA functions as an indispensable signal mediator for the nutrient-sensing system. J. Biol. Chem.. 2008.12; 283 (50): 35053-35059. ( PubMed , DOI )

  3. Tanaka T, Tsutsumi H, Nomura W, Tanabe Y, Ohashi N, Esaka A, Ochiai C, Sato J, Itotani K, Murakami T, Ohba K, Yamamoto N, Fujii N, Tamamura H: Structure-activity relationship study of CXCR4 antagonists bearing the cyclic pentapeptide scaffold: identification of the new pharmacophore. Org Biomol Chem. 2008.12; 6 (23): 4374-4377. ( PubMed , DOI )

  4. Akira Matsumoto, Amil Lindsay, Behrouz Abedian, David L. Kaplan: Silk Fibroin Solution Properties Related to Assembly and Structure MACROMOLECULAR BIOSCIENCE. 2008.11; 8 (11): 1006-1018. ( DOI )

  5. Abdu-Allah HH, Tamanaka T, Yu J, Zhuoyuan L, Sadagopan M, Adachi T, Tsubata T, Kelm S, Ishida H, Kiso M: Design, synthesis, and structure-affinity relationships of novel series of sialosides as CD22-specific inhibitors. J Med Chem. 2008.11; 51 (21): 6665-6681. ( PubMed , DOI )

  6. Shinya Takahashi, Yasuhiro Araki, Yuriko Ohya, Takeshi Sakuno, Shin-Ichi Hoshino, Kenji Kontani, Hiroshi Nishina, Toshiaki Katada: Upf1 potentially serves as a RING-related E3 ubiquitin ligase via its association with Upf3 in yeast. RNA. 2008.09; 14 (9): 1950-1958. ( PubMed , DOI )

  7. Kataoka-Hamai C, Inoue H, Miyahara Y: Detection of supported lipid bilayers using their electric charge Langmuir. 2008.09; 24 (17): 9916-9920.

  8. Nomura W, Tanabe Y, Tsutsumi H, Tanaka T, Ohba K, Yamamoto N, Tamamura H: Fluorophore labeling enables imaging and evaluation of specific CXCR4-ligand interaction at the cell membrane for fluorescence-based screening. Bioconjug Chem. 2008.09; 19 (9): 1917-1920. ( PubMed , DOI )

  9. Nakabayashi Makoto, Yamada Sachiko, Yoshimoto Nobuko, Tanaka Takashi, Igarashi Miharu, Ikura Teikichi, Ito Nobutoshi, Makishima Makoto, Tokiwa Hiroaki, DeLuca Hector F, Shimizu Masato: Crystal structures of rat vitamin D receptor bound to adamantyl vitamin D analogs: structural basis for vitamin D receptor antagonism and partial agonism. J Med Chem. 2008.09; 51 (17): 5320-5329. ( PubMed , DOI )

  10. Ozawa M,Honda K,Nakai I,Kishida A,Oosaki A: Hypaphorine, an indole alkaloid from Erythrina velutina, induced sleep on normal mice Bioorganic & Medicinal Chemistry Letters. 2008.07; 18 (4): 3992-3994. ( DOI )

  11. Shizue Ohsawa, Tomomi Watanabe, Toshiaki Katada, Hiroshi Nishina, Masayuki Miura: Novel antibody to human BASP1 labels apoptotic cells post-caspase activation. Biochem. Biophys. Res. Commun.. 2008.07; 371 (4): 639-643. ( PubMed , DOI )

  12. Shimizu Masato, Miyamoto Yukiko, Takaku Hajime, Matsuo Mayumi, Nakabayashi Makoto, Masuno Hiroyuki, Udagawa Nobuyuki, DeLuca Hector F, Ikura Teikichi, Ito Nobutoshi: 2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure. Bioorg Med Chem. 2008.07; 16 (14): 6949-6964. ( PubMed , DOI )

  13. Okamoto H, Sato T, Aizawa H: Transgenic technology for visualization and manipulation of the neural circuits controlling behavior in zebrafish. Dev Growth Differ. 2008.06; 50 Suppl 1 S167-75. ( PubMed , DOI )

  14. Hibi K, Ushio H, Fukuda H, Mitsubayashi K, Hayashi T, Ren H, Endo H: Immunomagnetic separation using carbonyl iron powder and flow cytometry for rapid detection of Flavobacterium psychrophilum. Anal Bioanal Chem. 2008.06; 391 (4): 1147-1152. ( PubMed , DOI )

  15. Kudo H, Yagi T, Chu MX, Saito H, Morimoto N, Iwasaki Y, Akiyoshi K, Mitsubayashi K: Glucose sensor using a phospholipid polymer-based enzyme immobilization method. Anal Bioanal Chem. 2008.06; 391 (4): 1269-1274. ( PubMed , DOI )

  16. Saito H, Shirai T, Kudo H, Mitsubayashi K: Electrochemical sensor with flavin-containing monooxygenase for triethylamine solution. Anal Bioanal Chem. 2008.06; 391 (4): 1263-1268. ( PubMed , DOI )

  17. Terazono H. Hattori A. Takei H. Takeda K. Yasuda K.: Development of 1480 nm Photothermal High-Speed Real-Time Polymerase Chain Reaction System for Rapid Nucleotide Recognition. Jpn J Appl Phy. 2008.06; 47 (6): 5212-5216. ( DOI )

  18. Shibata K. Terazono H. Hattori A. Yasuda K.: Collagen Micro-Flow Channels as an for In vitro Blood-Brain Barrier Model. Jpn J Appl Phys. 2008.06; 47 (6): 5208-5211. ( DOI )

  19. Nakata H, Steinberg SM, Koh Y, Maeda K, Takaoka Y, Tamamura H, Fujii N, Mitsuya H: Potent synergistic anti-human immunodeficiency virus (HIV) effects using combinations of the CCR5 inhibitor aplaviroc with other anti-HIV drugs. Antimicrob Agents Chemother. 2008.06; 52 (6): 2111-2119. ( PubMed , DOI )

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  67. Hirokazu Tamamura, Tomohiro Tanaka, Hiroshi Tsutsumi, Koji Nemoto, Satoko Mizokami, Nami Ohashi, Shinya Oishi & Nobutaka Fujii: Versatile Use of Acid-catalyzed Ring-opening of β-Aziridinyl-α,β-enoates to Stereoselective Synthesis of Peptidomimetics. Tetrahedron. 2007; 63 9243-9254.

  1. Matsumoto A, Chen J, Collette AL, Kim UJ, Altman GH, Cebe P, Kaplan DL: Mechanisms of silk fibroin sol-gel transitions. J Phys Chem B. 2006.11; 110 (43): 21630-21638. ( PubMed , DOI )

  2. Cui Y, Takamatsu H, Kakiuchi T, Ohba H, Kataoka Y, Yokoyama C, Onoe H, Watanabe Y, Hosoya T, Suzuki M, Noyori R, Tsukada H, Watanabe Y: Neuroprotection by a central nervous system-type prostacyclin receptor ligand demonstrated in monkeys subjected to middle cerebral artery occlusion and reperfusion: a positron emission tomography study. Stroke. 2006.11; 37 (11): 2830-2836. ( PubMed , DOI )

  3. Kudo H, Sawada T, Kazawa E, Yoshida H, Iwasaki Y, Mitsubayashi K: A flexible and wearable glucose sensor based on functional polymers with soft-MEMS techniques. Biosens Bioelectron. 2006.10; 22 (4): 558-562. ( PubMed , DOI )

  4. Wakamoto Y. Yasuda K.: Epigenetic inheritance of elongated phenotypes between generations revealed by individual-cell-based direct observation. Meas. Sci.Technol. 2006.10; 17 3171-3177. ( DOI )

  5. Kojima K, Kaneko T, Yasuda K: Role of the community effect of cardiomyocyte in the entrainment and reestablishment of stable beating rhythms. Biochem Biophys Res Commun. 2006.10; 351 (1): 209-215. ( PubMed , DOI )

  6. Umehara S, Pourmand N, Webb CD, Davis RW, Yasuda K, Karhanek M: Current rectification with poly-l-lysine-coated quartz nanopipettes. Nano Lett. 2006.10; 6 (11): 2486-2492. ( PubMed , DOI )

  7. Ayano S, Wakamoto Y, Yamashita S, Yasuda K: Quantitative measurement of damage caused by 1064-nm wavelength optical trapping of Escherichia coli cells using on-chip single cell cultivation system. Biochem Biophys Res Commun. 2006.10; 350 (3): 678-684. ( PubMed , DOI )

  8. Tamamura H, Tsutsumi H, Fujii N: The chemokine receptor CXCR4 as a therapeutic target for several diseases. Mini Rev Med Chem. 2006.09; 6 (9): 989-995. ( PubMed )

  9. Kawai-Noma S, Ayano S, Pack CG, Kinjo M, Yoshida M, Yasuda K, Taguchi H: Dynamics of yeast prion aggregates in single living cells. Genes Cells. 2006.09; 11 (9): 1085-1096. ( PubMed , DOI )

  10. Wakamoto Y, Yasuda K: Quantitative evaluation of cell-to-cell communication effects in cell group class using on-chip individual-cell-based cultivation system. Biochem Biophys Res Commun. 2006.09; 349 (3): 1130-1138. ( PubMed , DOI )

  11. Miyahara Yuji: A new general route to thiophenophanes: synthesis and properties of [n](2,5)thiophenophane-1,n-diones. J Org Chem. 2006.08; 71 (17): 6516-6521. ( PubMed , DOI )

  12. Matsumura K, Orita K, Wakamoto Y, Yasuda K: Phagocytic response to fully controlled plural stimulation of antigens on macrophage using on-chip microcultivation system. J Nanobiotechnology. 2006.08; 4 7. ( PubMed , DOI )

  13. Yamada M, Ohnishi J, Ohkawara B, Iemura S, Satoh K, Hyodo-Miura J, Kawachi K, Natsume T, Shibuya H: NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF). J Biol Chem. 2006.07; 281 (30): 20749-20760. ( PubMed , DOI )

  14. Daiju Kitagawa, Hiroaki Kajiho, Takahiro Negishi, Seiji Ura, Tomomi Watanabe, Teiji Wada, Hidenori Ichijo, Toshiaki Katada, Hiroshi Nishina: Release of RASSF1C from the nucleus by Daxx degradation links DNA damage and SAPK/JNK activation. EMBO J.. 2006.07; 25 (14): 3286-3297. ( PubMed , DOI )

  15. Endo H, Yonemori Y, Musiya K, Maita M, Shibuya T, Ren H, Hayashi T, Mitsubayashi K: A needle-type optical enzyme sensor system for determining glucose levels in fish blood. Anal Chim Acta. 2006.07; 573-574 117-124. ( PubMed , DOI )

  16. Hibi K, Abe A, Ohashi E, Mitsubayashi K, Ushio H, Hayashi T, Ren H, Endo H: Combination of immunomagnetic separation with flow cytometry for detection of Listeria monocytogenes. Anal Chim Acta. 2006.07; 573-574 158-163. ( PubMed , DOI )

  17. Fukuhara T, Hosoya T, Shimizu S, Sumi K, Oshiro T, Yoshinaka Y, Suzuki M, Yamamoto N, Herzenberg LA, Herzenberg LA, Hagiwara M: Utilization of host SR protein kinases and RNA-splicing machinery during viral replication. Proc Natl Acad Sci USA. 2006.07; 103 (30): 11329-11333. ( PubMed , DOI )

  18. Gharizadeh B, Akhras M, Nourizad N, Ghaderi M, Yasuda K, Nyrén P, Pourmand N: Methodological improvements of pyrosequencing technology. J Biotechnol. 2006.07; 124 (3): 504-511. ( PubMed , DOI )

  19. Tsuchiya Yuko, Kinoshita Kengo, Ito Nobutoshi, Nakamura Haruki: PreBI: prediction of biological interfaces of proteins in crystals. Nucleic Acids Res. 2006.07; 34 (Web Server issue): W320-W324. ( PubMed , DOI )

  20. Tamamura H, Tsutsumi H, Masuno H, Mizokami S, Hiramatsu K, Wang Z, Trent JO, Nakashima H, Yamamoto N, Peiper SC, Fujii N: Development of a linear type of low molecular weight CXCR4 antagonists based on T140 analogs. Org Biomol Chem. 2006.06; 4 (12): 2354-2357. ( PubMed , DOI )

  21. Tamamura H, Ojida A, Ogawa T, Tsutsumi H, Masuno H, Nakashima H, Yamamoto N, Hamachi I, Fujii N: Identification of a new class of low molecular weight antagonists against the chemokine receptor CXCR4 having the dipicolylamine-zinc(II) complex structure. J Med Chem. 2006.06; 49 (11): 3412-3415. ( PubMed , DOI )

  22. Moriguchi H. Yasuda K.: Photothermal microneedle etching: Improved three-dimensional microfabrication method for agarose gel for topographical control of cultured cell communities. Jpn J Appl Phys. 2006.06; 45 (30): L796-L799. ( DOI )

  23. Saito H*, Mitsubayashi K, Togawa T: Detection of needle puncture to blood vessel by using electric conductivity of blood for automatic blood sampling. Sensors and Actuators A: Physical. 2006.05; 125 446-450.

  24. Menu E, Asosingh K, Indraccolo S, De Raeve H, Van Riet I, Van Valckenborgh E, Vande Broek I, Fujii N, Tamamura H, Van Camp B, Vanderkerken K: The involvement of stromal derived factor 1alpha in homing and progression of multiple myeloma in the 5TMM model. Haematologica. 2006.05; 91 (5): 605-612. ( PubMed )

  25. Hanaoka H, Mukai T, Tamamura H, Mori T, Ishino S, Ogawa K, Iida Y, Doi R, Fujii N, Saji H: Development of a 111In-labeled peptide derivative targeting a chemokine receptor, CXCR4, for imaging tumors. Nucl Med Biol. 2006.05; 33 (4): 489-494. ( PubMed , DOI )

  26. Niida A, Tanigaki H, Inokuchi E, Sasaki Y, Oishi S, Ohno H, Tamamura H, Wang Z, Peiper SC, Kitaura K, Otaka A, Fujii N: Stereoselective synthesis of 3,6-disubstituted-3,6-dihydropyridin-2-ones as potential diketopiperazine mimetics using organocopper-mediated anti-SN2' reactions and their use in the preparation of low-molecule CXCR4 antagonists. J Org Chem. 2006.05; 71 (10): 3942-3951. ( PubMed , DOI )

  27. Yuichiro Yokoyama, Shuji Terai, Tsuyoshi Ishikawa, Koji Aoyama, Yohei Urata, Yoshio Marumoto, Hiroshi Nishina, Kazuyuki Nakamura, Kiwamu Okita, Isao Sakaida: Proteomic analysis of serum marker proteins in recipient mice with liver cirrhosis after bone marrow cell transplantation. Proteomics. 2006.04; 6 (8): 2564-2570. ( PubMed , DOI )

  28. Arakawa T, Shirasaki Y, Izumi T, Aoki T, Sugino H, Funatsu T, Shoji S: High speed particles and biomolecules sorting microsystem using thermosensitive hydrogel. Measurement science and technology. 2006.04; 17 (12): 3141-3146. ( DOI )

  29. Abraham S, Jeong EH, Arakawa T, Shoji S, Kim KC, Kim I, Go JS: Microfluidics assisted synthesis of well-defined spherical polymeric microcapsules and their utilization as potential encapsulants. Lab Chip. 2006.04; 6 (6): 752-756. ( PubMed , DOI )

  30. Harada T, Suzuki Y, Koshizuka S, Arakawa T, Shoji S: Simulation of Droplet Generation in Micro Flow using MPS Method. Japan Society of Mechanical Engineering International Journal Series B. 2006.04; 49 (3): 731-736. ( DOI )

  31. Joeng, EH, Arakawa T, Kim KC, Boo JS, Ko JS, Shin BS, Shoji S. Go JS: Realization of A Chip-Level Batch Process Chemical Plant with Quantitative Performance Evaluation. Key Engineering Materials. 2006.04; 326 (1): 262-272.

  32. Akagawa M, Ito S, Toyoda K, Ishii Y, Tatsuda E, Shibata T, Yamaguchi S, Kawai Y, Ishino K, Kishi Y, Adachi T, Tsubata T, Takasaki Y, Hattori N, Matsuda T, Uchida K: Bispecific abs against modified protein and DNA with oxidized lipids. Proc Natl Acad Sci U S A. 2006.04; 103 (16): 6160-6165. ( PubMed , DOI )

  33. Takashi Horiuchi、Akio Kishida、Toru Masuzawa、Kazumi Mizuguchi、Motonobu Nishimura、Takafumi Okoshi、Takahiro Shinzato、Eisuke Tatsumi,Yasuko Tomizawa,Hiroshi Watanabe: Journal of Artficial Organs 2005:the year in review Journal of Artficial Organs. 2006.03; 9 (1): 1-7.

  34. Sakata Toshiya, Miyahara Yuji: DNA sequencing based on intrinsic molecular charges. Angew Chem Int Ed Engl. 2006.03; 45 (14): 2225-2228. ( PubMed , DOI )

  35. Xianyan Wang, Andrea Daley, Hyeon Joo Kim, Peng Xu, Akira Matsumoto, David L. Kaplan: Controlled release biomaterial nanoscale coatings by stepwise deposition of silk fibroin 2006.03;

  36. Otuska K, Goto T, Amagai H, Ishii N, Endo H, Mitsubayashi K*: Biochemical sniffer for odourless hydrogen peroxide vapour. The International Journal of Environmental Analytical Chemistry. 2006.03; 86 1049-1056.

  37. C.Yoshikawa,A.Goto,Y.Tsujii,T.Fukuda,T.Kimura,K.Yamamoto,A.Kishida: Protein Repellency of Well-Defined,Concentrated Poly(2-hydroxyethyl methacrylate) Brushes by the Size-Exclusion Effect Macromolecules. 2006.03; 39 (6): 2284-2290. ( DOI )

  38. Kasyanov A, Tamamura H, Fujii N, Xiong H: HIV-1 gp120 enhances giant depolarizing potentials via chemokine receptor CXCR4 in neonatal rat hippocampus. Eur J Neurosci. 2006.03; 23 (5): 1120-1128. ( PubMed , DOI )

  39. Singh Savita Devi, Hiroyuki Hagiyama, Takahiro Adachi, Nobuyuki Miyasaka, Takeshi Tsubata: The tumor suppressor p53 is not required for antigen receptor-mediated apoptosis of B lymphocytes Signal Transduction. 2006.02; 6 (1): 54-61. ( DOI )

  40. Honma M, Higuchi O, Shirakata M, Yasuda T, Shibuya H, Iemura S, Natsume T, Yamanashi Y: Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases. Genes Cells. 2006.02; 11 (2): 143-151. ( PubMed , DOI )

  41. Tsuyoshi Ishikawa, Shuji Terai, Yohei Urata, Yoshio Marumoto, Koji Aoyama, Isao Sakaida, Tomoaki Murata, Hiroshi Nishina, Koh Shinoda, Shunji Uchimura, Yoshihiko Hamamoto, Kiwamu Okita: Fibroblast growth factor 2 facilitates the differentiation of transplanted bone marrow cells into hepatocytes. Cell Tissue Res.. 2006.02; 323 (2): 221-231. ( PubMed , DOI )

  42. Otsuka K*, Sumino T, Miyagi M, Togawa T, Mitsubayashi K: Measurement with a chemical sensor and a dialysis probe supported by a null method. Sensors and Actuators B. 2006.02; 120 252-258.

  43. Toyota T, Tsuha H, Yamada K, Takakura K, Yasuda K, Sugawara T. : Fluorescence microscopic investigation on morphological changes of giant multilamellar vesicles induced by amphiphilic additives Langmuir . 2006.02; 22 (5): 1976-1981. ( DOI )

  44. Hosoya T, Sumi K, Doi H, Wakao M, Suzuki M: Rapid methylation on carbon frameworks useful for the synthesis of 11CH3-incorporated PET tracers: Pd(0)-mediated rapid coupling of methyl iodide with an alkenyltributylstannane leading to a 1-methylalkene. Org Biomol Chem. 2006.02; 4 (3): 410-415. ( PubMed , DOI )

  45. Mitsubayashi K, Minamide T, Otsuka K and Kudo H, Saito H: Bioelectronic sniffer for nicotine using enzyme inhibition. Anal. Chim. Acta. 2006.01; 573-574 69-74.

  46. Teiji Wada, Tomoki Nakashima, Nishina Hiroshi, Josef M Penninger: RANKL-RANK signaling in osteoclastogenesis and bone disease. Trends Mol Med. 2006.01; 12 (1): 17-25. ( PubMed , DOI )

  47. Mitsubayashi K, Minamide T, Otsuka K and Kudo H, Saito H: Optical bio-sniffer for methyl mercaptan in halitosis. Anal. Chim. Acta. 2006.01; 573-574 75-80.

  48. Saito H, Kaneko Y, Hashimoto Y, Shirai T, Mitsubayashi K*: Ammonia sensor with flavin-containing monooxygenase. The International Journal of Environmental Analytical Chemistry. 2006.01; 86 1057-1064.

  49. M.Okada,S.Yasuda,T.Kimura,M.Iwasaki,,S.Ito,A.Kishida,T.Furuzono: Optimization of amino group density on surfaces of titanium dioxide nanoparticles covalently bonded to a silicone substrate for antibacterial and cell adhesion activities Journal of Biomedical Materials Research Part A. 2006.01; 76A (1): 95-101. ( DOI )

  50. Hulme JP, Gwak J, Miyahara Y: Biomolecular embossing J Am Chem Soc. 2006.01; 128 (2): 390-391.

  51. Tamamura H, Tsutsumi H: Specific probes for chemokine receptors. Chem Biol. 2006.01; 13 (1): 8-10. ( PubMed , DOI )

  52. Niida A, Wang Z, Tomita K, Oishi S, Tamamura H, Otaka A, Navenot JM, Broach JR, Peiper SC, Fujii N: Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity. Bioorg Med Chem Lett. 2006.01; 16 (1): 134-137. ( PubMed , DOI )

  53. Murano N, Murano M, Ishida K, Kawakami K, Abe Y, Inoue T, Morita E, Yasumoto S, Toshina K, Nishikawa T, Ito S, Hirata I, Katsu K,: Therapeutic effect of SHI-219, a novel water soluble prodrug of EG626(Phtalazinol), on mouse dextran sodium sulfate -induced colitis, Bull. Osaka. Med. Coll.. 2006; 52 69-79.

  54. Kwangwoo Nam,Tsuyoshi Kimura,Akio Kishida: Influence of Cross-linking on Physicochemical and Biological Properties of Collagen-Phospholipid Polymer Hybrid Gel Transactions of the Materials Research Society of Japan. 2006; 31 (3): 735-738.

  55. Xianyan Wang; Hyeon Joo Kim; Cheryl Wong; Charu Vepari; Akira Matsumoto; David L. Kaplan: Fibrous Protein and Tissue Engineering. Materials Today. 2006; 9 (12): 44-53.

  56. Shinya Oishi, Kazuhide Miyamoto, Ayumu Niida, Mikio Yamamoto, Keiichi Ajito, Hirokazu Tamamura, Akira Otaka, Yoshihiro Kuroda, Akira Asai & Nobutaka Fujii: Application of Tri- and Tetrasubstituted Alkene Dipeptide Mimetics to Conformational Studies of Cyclic RGD Peptides. Tetrahedron. 2006; 62 1416-1424.

  57. Miyahara Y, Sakata T: Electrical Detection of Bio-molecular Recognition Using Insulated Gate Field Effect Transistors Hyomen Kagaku. 2006; 27 (1): 13-20. ( DOI )

  58. Hirokazu Tamamura & Hiroshi Tsutsumi: Specific Probes for Chemokine Receptors Chem. Biol.. 2006; 13 8-10.

  59. Sato N, Kondo M, Arai K.: The orphan nuclear receptor GCNF recruits DNA methyltransferase for Oct-3/4 silencing. Biochem Biophys Res Commun.. 2006; 344 (3): 845-51. ( PubMed )

  60. Sekita Y, Wagatsuma H, Irie M, Kobayashi S, Kohda T, Matsuda J, Yokoyama M, Ogura A, Schuster-Gossler K, Gossler A, Ishino F, Kaneko-Ishino T: Aberrant regulation of imprinted gene expression in Gtl2lacZ mice. Cytogenet Genome Res.. 2006; 113 (1-4): 223-229.

  61. Sakata T, Miyahara Y: DNA sequencing based on intrinsic molecular charges Angew Chem Int Edit. 2006; 45 (14): 2225-2228.

  1. Iguchi S, Mitsubayashi K*, Uehara T, Ogawa M: A wearable oxygen sensor for transcutaneous blood gas monitoring at the conjunctiva. Sensors and Actuators B: Chemical. 2005.12; 108 733-737.

  2. Moriguchi T, Urushiyama S, Hisamoto N, Iemura S, Uchida S, Natsume T, Matsumoto K, Shibuya H: WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1. J Biol Chem. 2005.12; 280 (52): 42685-42693. ( PubMed , DOI )

  3. Isao Sakaida, Shuji Terai, Hiroshi Nishina, Kiwamu Okita: Development of cell therapy using autologous bone marrow cells for liver cirrhosis. Med Mol Morphol. 2005.12; 38 (4): 197-202. ( PubMed , DOI )

  4. Tamamura H, Esaka A, Ogawa T, Araki T, Ueda S, Wang Z, Trent JO, Tsutsumi H, Masuno H, Nakashima H, Yamamoto N, Peiper SC, Otaka A, Fujii N: Structure-activity relationship studies on CXCR4 antagonists having cyclic pentapeptide scaffolds. Org Biomol Chem. 2005.12; 3 (24): 4392-4394. ( PubMed , DOI )

  5. Tamamura H, Fujii N: The therapeutic potential of CXCR4 antagonists in the treatment of HIV infection, cancer metastasis and rheumatoid arthritis. Expert Opin Ther Targets. 2005.12; 9 (6): 1267-1282. ( PubMed , DOI )

  6. Wang X, Kim HJ, Xu P, Matsumoto A, Kaplan DL: Biomaterial coatings by stepwise deposition of silk fibroin. Langmuir. 2005.11; 21 (24): 11335-11341. ( PubMed , DOI )

  7. Masataka Asagiri, Kojiro Sato, Takako Usami, Sae Ochi, Hiroshi Nishina, Hiroki Yoshida, Ikuo Morita, Erwin F Wagner, Tak W Mak, Edgar Serfling, Hiroshi Takayanagi: Autoamplification of NFATc1 expression determines its essential role in bone homeostasis. J. Exp. Med.. 2005.11; 202 (9): 1261-1269. ( PubMed , DOI )

  8. S.Nishino,Y.Kitamura,A.Kishida,H.Yoshizawa: Preparation and Interfaccial Properties of a Novel Biodegradable Polymer Surfactant:Poly(etylene Oxide monooleate-bloc-DL-lactide) Macromolecular Bioscience . 2005.11; 5 (11): 1066-1073. ( DOI )

  9. Akira Kawaguchi,Akio Kishida,Tetsuji Yamaoka: Static Cardiomyoplasty with Synthetic Elastic Net Suppresses Ventricular Dilatation and Dysfunction After Myocardial Infarction in the Rat:An Acute Study Journal of Cardiac Surgery . 2005.11; 20 (6): S12-S16. ( DOI )

  10. Sakata Toshiya, Miyahara Yuji: Detection of DNA recognition events using multi-well field effect devices. Biosens Bioelectron. 2005.11; 21 (5): 827-832. ( PubMed , DOI )

  11. Sakata T, Miyahara Y: Detection of DNA recognition events using multi-well field effect devices Biosensors & Bioelectronics. 2005.11; 21 (5): 827-832.

  12. Ueda S, Fujita M, Tamamura H, Fujii N, Otaka A: Photolabile protection for one-pot sequential native chemical ligation. Chembiochem. 2005.11; 6 (11): 1983-1986. ( PubMed , DOI )

  13. Mitsubayashi K, Matsunaga H, Nishio G, Toda S, Nakanishi Y, Saito H, Ogawa M, Ohtsuka K: Bio-sniffer sticks for breath analysis after drinking. Sensors and Actuators B. 2005.10; 108 660-664.

  14. Tamamura H, Otaka A, Fujii N: Development of anti-HIV agents targeting dynamic supramolecular mechanism: entry and fusion inhibitors based on CXCR4/CCR5 antagonists and gp41-C34-remodeling peptides. Curr HIV Res. 2005.10; 3 (4): 289-301. ( PubMed )

  15. Burger M, Hartmann T, Krome M, Rawluk J, Tamamura H, Fujii N, Kipps TJ, Burger JA: Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells. Blood. 2005.09; 106 (5): 1824-1830. ( PubMed , DOI )

  16. Minamide T, Mitsubayashi K*, Saito H: Bioelectronic sniffer with monoamine oxidase for methyl mercaptan vapor. Sensors and Actuators B: Chemical. 2005.08; 108 639-645.

  17. Ohnishi J, Ohnishi E, Shibuya H, Takahashi T: Functions for proteinases in the ovulatory process. Biochim Biophys Acta. 2005.08; 1751 (1): 95-109. ( PubMed , DOI )

  18. M.Matsusaki,T.Serizawa,A.Kishida,M.Akashi: Novel functional biodegradable polymer. III. The construction of poly(γ‐glutamic acid)‐sulfonate hydrogel with fibroblast growth factor‐2 activity Journal of Biomedical Materials Research Part A. 2005.06; 73 (4): 485-491. ( DOI )

  19. Minamide T, Mitsubayashi K*, Jaffrezic-Renault N, Hibi K, Endo H, Saito H: Bioelectronic sniffer with monoamine oxidase for halitosis monitoring. The Analyst. 2005.06; 130 1490-1494.

  20. Kon T, Nakakura S, Mitsubayashi K: Intracellular analysis of Saccharomyces cerevisiae using CLSM after ultrasonic treatments. Nanomedicine : nanotechnology, biology, and medicine. 2005.06; 1 (2): 159-163. ( PubMed , DOI )

  21. T.Furuzono,D. Walsh,S.Yasuda,J.Tanaka,A.Kishida: Preparation of plated β-tricalcium phosphate containing of hydroxyapatite for use in bonded inorgainc-organic composites Journal of Materials Science. 2005.05; 40 (9-10): 2595-2597. ( DOI )

  22. T.Furuzono,S.Yasuda,J.Tanaka,A.Kishida: A unique preparation method of self-assembled spherical particles consisting of hydroxyapatite nanocrystals modified by amino groups. Journal of Materials Science. 2005.05; 40 (9-10): 2627-2629. ( DOI )

  23. Taro Takami, Shuji Terai, Yuichiro Yokoyama, Haruko Tanimoto, Kunihiko Tajima, Koichi Uchida, Takahiro Yamasaki, Isao Sakaida, Hiroshi Nishina, Snorri S Thorgeirsson, Kiwamu Okita: Human homologue of maid is a useful marker protein in hepatocarcinogenesis. Gastroenterology. 2005.05; 128 (5): 1369-1380. ( PubMed )

  24. C.Yoshikawa,A.Goto,Y.Tsujii,T.Fukuda,K.Yamamoto,A.Kishida: Fabrication of high-density polymer brush on polyme substrate by surface-initiated living radical polymerization. Macromolecules. 2005.05; 38 (11): 4604-4610. ( DOI )

  25. Tamamura H, Araki T, Ueda S, Wang Z, Oishi S, Esaka A, Trent JO, Nakashima H, Yamamoto N, Peiper SC, Otaka A, Fujii N: Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide scaffolds. J Med Chem. 2005.05; 48 (9): 3280-3289. ( PubMed , DOI )

  26. Kojima K, Kaneko T, Yasuda K: Stability of beating frequency in cardiac myocytes by their community effect measured by agarose microchamber chip. Journal of Nanobiotechnology . 2005.05; 3 (4): ( DOI )

  27. Sakata T, Miyahara Y: Potentiometric detection of single nucleotide polymorphism by using a genetic field-effect transistor Chembiochem. 2005.04; 6 (4): 703-710.

  28. Sakata T, Matsumoto S, Nakajima Y, Miyahara Y: Potential behavior of biochemically modified gold electrode for extended-gate field-effect transistor Japanese Journal of Applied Physics Part 1-Regular Papers Brief Communications & Review Papers. 2005.04; 44 (4B): 2860-2863.

  29. Sakata T, Kamahori M, Miyahara Y: DNA analysis chip based on field-effect transistors Japanese Journal of Applied Physics Part 1-Regular Papers Brief Communications & Review Papers. 2005.04; 44 (4B): 2854-2859.

  30. Westbrook John, Ito Nobutoshi, Nakamura Haruki, Henrick Kim, Berman Helen M: PDBML: the representation of archival macromolecular structure data in XML. Bioinformatics. 2005.04; 21 (7): 988-992. ( PubMed , DOI )

  31. Kota Saito, Yasuhiro Araki, Kenji Kontani, Hiroshi Nishina, Toshiaki Katada: Novel role of the small GTPase Rheb: its implication in endocytic pathway independent of the activation of mammalian target of rapamycin. J. Biochem.. 2005.03; 137 (3): 423-430. ( PubMed , DOI )

  32. Percherancier Y, Berchiche YA, Slight I, Volkmer-Engert R, Tamamura H, Fujii N, Bouvier M, Heveker N: Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo- and heterodimers. J Biol Chem. 2005.03; 280 (11): 9895-9903. ( PubMed , DOI )

  33. Wakamoto Y, Ramsden J, Yasuda K: Single-cell growth and division dynamics showing epigeneticcorrelations. Analyst. 2005.03; 130 (3): 311 -317. ( PubMed , DOI )

  34. Zannettino AC, Farrugia AN, Kortesidis A, Manavis J, To LB, Martin SK, Diamond P, Tamamura H, Lapidot T, Fujii N, Gronthos S: Elevated serum levels of stromal-derived factor-1alpha are associated with increased osteoclast activity and osteolytic bone disease in multiple myeloma patients. Cancer Res. 2005.03; 65 (5): 1700-1709. ( PubMed , DOI )

  35. Hosoya T, Hiramatsu T, Ikemoto T, Aoyama H, Ohmae T, Endo M, Suzuki M: Design of dantrolene-derived probes for radioisotope-free photoaffinity labeling of proteins involved in the physiological Ca2+ release from sarcoplasmic reticulum of skeletal muscle. Bioorg Med Chem Lett. 2005.03; 15 (5): 1289-1294. ( PubMed , DOI )

  36. Aizawa H, Bianco IH, Hamaoka T, Miyashita T, Uemura O, Concha ML, Russell C, Wilson SW, Okamoto H: Laterotopic representation of left-right information onto the dorso-ventral axis of a zebrafish midbrain target nucleus. Curr Biol. 2005.02; 15 (3): 238-243. ( PubMed , DOI )

  37. Mitsubayashi K*, Nishio G, Nakayama Y, Amagai H, Watanabe H: Jaffrezic-Renault N, Noguer T, Marty J.L, Bioelectric sniffers for formaldehyde in the gas phase. Intern. J. Environ. Anal. Chem. 2005.02; 85 917-925.

  38. Mitsubayashi K, Matsunaga H, Nishio G, Toda S, Nakanishi Y: Bioelectronic sniffers for ethanol and acetaldehyde in breath air after drinking. Biosens Bioelectron. 2005.02; 20 (8): 1573-1579. ( PubMed , DOI )

  39. Piovan E, Tosello V, Indraccolo S, Cabrelle A, Baesso I, Trentin L, Zamarchi R, Tamamura H, Fujii N, Semenzato G, Chieco-Bianchi L, Amadori A: Chemokine receptor expression in EBV-associated lymphoproliferation in hu/SCID mice: implications for CXCL12/CXCR4 axis in lymphoma generation. Blood. 2005.02; 105 (3): 931-939. ( PubMed , DOI )

  40. A.Korematsu,T.Furuzono,A.Kishida: Synthesis of block copolymers containing chain-controlled aramid and fluoroethylene segments Macromolecular Materials and Engineering. 2005.01; 290 (1): 66-71. ( DOI )

  41. M.Matsusaki,T.Serizawa,A.Kishida,M.Akashi: Novel functional biodegradable polymer II: bFGF Stabilizing activity of Poly(g-glutamic acid) sulfonate. Biomacromolecules. 2005.01; 6 (1): 400-407. ( DOI )

  42. A.Korematsu,T.Furuzono,S.Yasuda,J.Tanaka,A.Kishida: Nano-scaled hydroxyapatite/polymer composite III. Coating of sintered hydroxyapatite particles on poly(4-methacryloyloxyethyl trimellitate anhydride)-grafted silk fibroin fibers Journal of Materials Science: Materials in Medicine. 2005.01; 16 (1): 67-71. ( DOI )

  43. Nameki D, Kodama E, Ikeuchi M, Mabuchi N, Otaka A, Tamamura H, Ohno M, Fujii N, Matsuoka M: Mutations conferring resistance to human immunodeficiency virus type 1 fusion inhibitors are restricted by gp41 and Rev-responsive element functions. J Virol. 2005.01; 79 (2): 764-770. ( PubMed , DOI )

  44. Tamamura H, Hiramatsu K, Ueda S, Wang Z, Kusano S, Terakubo S, Trent JO, Peiper SC, Yamamoto N, Nakashima H, Otaka A, Fujii N: Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131. J Med Chem. 2005.01; 48 (2): 380-391. ( PubMed , DOI )

  45. Hirata A, Murakami Y, Atsumi T, Shoji M, Ogiwara T, Shibuya K, Ito S, Yokoe I, Fujisawa S: Ferulic acid dimmer inhibits lipopolysaccharide-stimulated cyclooxygenase-2 expression in Macrophages. in vivo. 2005; 19 849-854.

  46. Murakami Y, Ito S, Atsumi T, Fujisawa S: Theoretical prediction of the relationship between phenol function and COX-2/AP-1 inhibition for ferulic acid-rrelated compounds. in vivo. 2005; 19 1039-1044.

  47. Sezik E, Aslan M, Yesilada E, Ito S: Hypoglycaemic activity of Gentiana olivieri and isolation of the active constituent through bioassay- directed fractionation techniques. Life Science. 2005; 76 1223-1238.

  48. Hyeon Joo Kim; Hyun Suk Kim; Akira Matsumoto; In-Joo Chin; Hyoung-Joon Jin; David L. Kaplan: Processing Windows for Forming Silk Fibroin Biomaterials into 3D Porous Matrices. Aust. J. Chem.. 2005; 58 (10): 716-720.

  49. Shuji Terai, Isao Sakaida, Hiroshi Nishina, Kiwamu Okita: Lesson from the GFP/CCl4 model--translational research project: the development of cell therapy using autologous bone marrow cells in patients with liver cirrhosis. J Hepatobiliary Pancreat Surg. 2005; 12 (3): 203-207. ( PubMed , DOI )

  50. Kota Saito, Hiroaki Kajiho, Yasuhiro Araki, Hiroshi Kurosu, Kenji Kontani, Hiroshi Nishina, Toshiaki Katada: Purification and analysis of RIN family-novel Rab5 GEFs. Meth. Enzymol.. 2005; 403 276-283. ( PubMed , DOI )

  51. Suzuki I, Sugio Y, Jimbo Y, Yasuda K: Stepwise pattern modification of neuronal network in photo-thermally-etched agarose architecture on multi-electrode array chip for individual-cell-based electrophysiological measurement. Lab Chip. 2005; 5 241 -247.

  52. Kaneko T, Kojima K, Yasuda K: Using agarose microchamber system, measurements of community effects of the cardiomyocytes and the heterogeneous cell types Proceedings of The 6th International Conference on Intelligent Materials and Systems. 2005; 183-186.

  53. H.Arimura,T.Ouchi,A.Kishida,Y.Ohya: Preparation of a hyaluronic acid hydrogel through polyion complex formation using cationic polylactide-based microspheres as a biodegrable cross-linking agent Journal of Biomaterials Science, Polymer Edition . 2005; 16 (11): 1347-1358. ( DOI )

  54. Ayumu Niida, Shinya Oishi, Yoshikazu Sasaki, Makiko Mizumoto, Hirokazu Tamamura, Nobutaka Fujii & Akira Otaka: Facile Access to (Z)-Alkene-containing Diketopiperazine Mimetics Utilizing Organocopper-mediated Anti-SN2' Reactions. Tetrahedron Lett.. 2005; 46 4183-4186.

  55. Margitta Retz, Sachdev S. Sidhu, Jan Lehmann, Hirokazu Tamamura, Nobutaka Fujii & Carol Basbaum: New HIV-Drug Inhibits in Vitro Bladder Cancer Migration and Invasion Eur. Urol.. 2005; 48 (6): 1025-1030.

  56. Jayendra B. Bhonsle, Zi-xuan Wang, Hirokazu Tamamura, Nobutaka Fujii, Stephen C. Peiper & John O. Trent: A Simple, Automated Quasi-4D-QSAR, Quasi-multi Way PLS Approach to Develop Highly Predictive QSAR Models for Highly Flexible CXCR4 Inhibitor Cyclic Peptide Ligands Using Scripted Common Molecular Modeling Tools. QSAR Comb. Sci.. 2005; 24 (5): 620-630.

  57. 和田悌司, 中島友樹, 仁科博史, Josef M Penninger: アダプター分子Gab2は骨密度を制御する 細胞工学. 2005; (24): 704-705.

  1. T.Kimura,A.Okuno,K.Miyazaki,T.Furuzono,Y.Ohya,T.Ouchi,S.Mutsuo,H,Yoshizawa,Y.Kitamura,T.Fujisato ,A.Kishida: Novel PVA-DNA nanoparticles prepared by ultra high pressure technology for gene delivery 2004.12; 24 (6-8): 797-801. ( DOI )

  2. Sakata T, Kamahori M, Miyahara Y: Immobilization of oligonucleotide probes on Si3N4 surface and its application to genetic field effect transistor Materials Science & Engineering C-Biomimetic and Supramolecular Systems. 2004.12; 24 (6-8): 827-832.

  3. Adachi S, Jigami T, Yasui T, Nakano T, Ohwada S, Omori Y, Sugano S, Ohkawara B, Shibuya H, Nakamura T, Akiyama T: Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling. Cancer Res. 2004.12; 64 (23): 8496-8501. ( PubMed , DOI )

  4. Yasuda K: Biotechnology approach to determination of genetic and epigenetic control in cells. Journal of Nanobiotechnology . 2004.11; 2 11.

  5. Aoyama Y, Urushiyama S, Yamada M, Kato C, Ide H, Higuchi S, Akiyama T, Shibuya H: MFB-1, an F-box-type ubiquitin ligase, regulates TGF-beta signalling. Genes Cells. 2004.11; 9 (11): 1093-1101. ( PubMed , DOI )

  6. Ozawa S, Sugano K, Sonehara T, Fukuzono S, Ichikawa A, Fukayama N, Taylor M, Miyahara Y, Irie T: High resolution for single-strand conformation polymorphism analysis by capillary electrophoresis Anal Chem. 2004.10; 76 (20): 6122-6129.

  7. T.Furuzono,S.Yasuda,T.Kimura,J.Tanaka,A.Kishida: Nano-scaled hydroxyapatite/polymer composite IV. Fabrication and cell adhesion of a 3D scaffold made of composite material with a silk fibroin substrate to develop a percuataneous device. Journal of Artificial Organs . 2004.09; 7 (3): 137-144. ( DOI )

  8. Miyahara Yuji, Goto Kenta, Oka Masakazu, Inazu Takahiko: Remarkably facile ring-size control in macrocyclization: synthesis of hemicucurbit[6]uril and hemicucurbit[12]uril. Angew Chem Int Ed Engl. 2004.09; 43 (38): 5019-5022. ( PubMed , DOI )

  9. Allen CD, Ansel KM, Low C, Lesley R, Tamamura H, Fujii N, Cyster JG: Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5. Nat Immunol. 2004.09; 5 (9): 943-952. ( PubMed , DOI )

  10. Tamamura H, Sigano DM, Lewin NE, Peach ML, Nicklaus MC, Blumberg PM, Marquez VE: Conformationally constrained analogues of diacylglycerol (DAG). 23. Hydrophobic ligand-protein interactions versus ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C). J Med Chem. 2004.09; 47 (20): 4858-4864. ( PubMed , DOI )

  11. Kojima K, Kaneko T, Yasuda K: A novel method of cultivating cardiac myocytes in agarose microchamber chips for studying cell synchronization. Journal of Nanobiotechnology . 2004.09; 2 9.

  12. Suzuki M, Doi H, Kato K, Hosoya T, Watanabe Y, Watanabe Y: Designed molecular probes in brain research: molecular imaging of IP2 receptor in the human brain. Jpn J Neuropsychopharmacol. 2004.08; 24 (4): 221-229. ( PubMed )

  13. Otaka A, Ueda S, Tomita K, Yano Y, Tamamura H, Matsuzaki K, Fujii N: Facile synthesis of membrane-embedded peptides utilizing lipid bilayer-assisted chemical ligation. Chem Commun (Camb). 2004.08; (15): 1722-1723. ( PubMed , DOI )

  14. Aizawa H, Sato Y, Maekawa M, Fujisawa H, Hirata T, Yuasa S: Development of the amygdalohypothalamic projection in the mouse embryonic forebrain. Anat Embryol (Berl). 2004.07; 208 (4): 249-264. ( PubMed , DOI )

  15. Suzuki I, Sugio Y, Moriguchi H, Jimbo Y, Yasuda K: Modification of a neuronal network direction using stepwise photo-thermal etching of an agarose architecture. Journal of Nanobiotechnology . 2004.07; 2 7.

  16. Tamamura H, Fujisawa M, Hiramatsu K, Mizumoto M, Nakashima H, Yamamoto N, Otaka A, Fujii N: Identification of a CXCR4 antagonist, a T140 analog, as an anti-rheumatoid arthritis agent. FEBS Lett. 2004.07; 569 (1-3): 99-104. ( PubMed , DOI )

  17. Yamamoto N, Yang R, Yoshinaka Y, Amari S, Nakano T, Cinatl J, Rabenau H, Doerr HW, Hunsmann G, Otaka A, Tamamura H, Fujii N, Yamamoto N: HIV protease inhibitor nelfinavir inhibits replication of SARS-associated coronavirus. Biochem Biophys Res Commun. 2004.06; 318 (3): 719-725. ( PubMed , DOI )

  18. Tamamura H, Fujii N: Two orthogonal approaches to overcome multi-drug resistant HIV-1s: development of protease inhibitors and entry inhibitors based on CXCR4 antagonists. Curr Drug Targets Infect Disord. 2004.06; 4 (2): 103-110. ( PubMed )

  19. Takahashi K, Hattori A, Suzuki I, Ichiki T, Yasuda K: Non-destructive on-chip cell sorting system with real-time microscopic image processing. Journal of Nanobiotechnology . 2004.06; 2 5.

  20. Muraki M, Ohkawara B, Hosoya T, Onogi H, Koizumi J, Koizumi T, Sumi K, Yomoda J, Murray MV, Kimura H, Furuichi K, Shibuya H, Krainer AR, Suzuki M, Hagiwara M: Manipulation of alternative splicing by a newly developed inhibitor of Clks. J Biol Chem. 2004.06; 279 (23): 24246-24254. ( PubMed , DOI )

  21. A.Korematsu,T.Furuzono,S.Yasuda,J.Tanaka,A.Kishida: Nano-scaled hydroxyapatite/polymer composite II. Coating of sintered hydroxyapatite particles on poly(2-(o-[1′-methylpropylideneamino] carboxyamino) ethyl methacrylate)-grafted silk fibroin fibers through covalent linkage Journal of Materials Science. 2004.05; 39 (9): 3221-3225. ( DOI )

  22. Matsumoto A, Yoshida R, Kataoka K: Glucose-responsive polymer gel bearing phenylborate derivative as a glucose-sensing moiety operating at the physiological pH. Biomacromolecules. 2004.05; 5 (3): 1038-1045. ( PubMed , DOI )

  23. Yasuda K: On-chip single-cell-based microcultivation method for analysis of genetic information and epigenetic correlation of cells. Journal of molecular recognition . 2004.05; 17 (3): 186-193.

  24. H. Kudo, T. Arakawa, S. Ohtsuka, T. Izumi, S. Shoji, H. Sato, H. Kobayashi, K. Mori, T. Homma, T. Osaka, N. Iyomoto, R. Fujimoto, K. Mitsuda, N. Y. Yamasaki, T. Oshima, K. Futamoto, Y. Takei, T. Ichitsubo, T. Fujimori, Y. Ishisaki, U. Morita, T. Koga, K. Shinozaki, K. Sato, T. Ohashi, Y. Kuroda, M. Onishi, K. Otake, F. Beppu: High sensitive X-ray microcalorimeter using Bi-Au microabsorber for imaging applications. Japanese Journal of Applied Physics. 2004.04; 43 1190-1195. ( DOI )

  25. H. Kudo, T. Nakamura, T. Arakawa, S. Ohtsuka, T. Izumi, S. Shoji, H. Sato, H. Kobayashi, K. Mori, T. Homma, T. Osaka, K. Mitsuda, N. Y. Yamasaki, R. Fujimoto, N. Iyomoto, T. Oshima, K. Futamoto, Y. Takei, T. Ichitsubo, T. Fujimori, Y. Ishisaki, U. Morita, T. Koga, K. Sato, T. Ohashi, Y. Kuroda, M. Onishi, K. Otake, F. Beppu: Prototype of the high sensitive x-ray microcalorimeter for x-ray imaging. Sensors and Actuators A: Physical. 2004.04; 114 (2-3): 171-175. ( DOI )

  26. Peng H, Huang Y, Rose J, Erichsen D, Herek S, Fujii N, Tamamura H, Zheng J: Stromal cell-derived factor 1-mediated CXCR4 signaling in rat and human cortical neural progenitor cells. J Neurosci Res. 2004.04; 76 (1): 35-50. ( PubMed , DOI )

  27. Inoue I, Shiomi D, Kawagishi I, Yasuda K. : Simultaneous measurement of sensor-protein dynamics and motility of a single cell by on-chip microcultivation system. Journal of Nanobiotechnology . 2004.04; 2 4.

  28. T. Arakawa, H. Kudo, H. Sato, H. Kobayashi, T. Izumi, S. Ohtsuka, K. Mori, S. Shoji, T. Osaka, T. Homma, K. Mitsuda, N. Yamasaki, R. Fujimoto, N. Iyomoto, T. Oshima, K. Futamoto, Y. Takei, T. Ichitsubo, T. Fujimori, K. Yoshida, Y. Ishisaki, U. Morita, T. Koga, K. Shinozaki, K. Sato, N. Takai, T. Ohashi, Y. Kuroda, M. Onishi, M. Goto and F. Beppu: Fabrication of multi-pixel TES micro calorimeters with an electrodeposited Sn absorber and Bi absorber. Nuclear Instruments and Methods in Physics Research Section A. 2004.04; 520 (1-3): 566-569. ( DOI )

  29. Y. Ishisaki, U. Morita, T. Koga, K. Shinozaki, K. Sato, N. Takai, T. Ohashi, T. Arakawa, H. Kudo, H. Sato, H. Kobayashi, T. Izumi , S. Ohtsuka, K. Mori, S. Shoji, T. Osaka, T. Homma, K. Mitsuda, N. Y. Yamasaki, R. Fujimoto, N. Iyomoto, T. Oshima, K. Futamoto, Y. Takei, T. Ichitsubo, T. Fujimori, K. Yoshida, Y. Kuroda, M. Onishi, M. Goto, F. Beppu: Performance analyses of TES microcalorimeters with mushroom shaped X-ray absorbers made of Sn and Bi. Nuclear Instruments and Methods in Physics Research Section A. 2004.04; 520 (1-3): 456-459. ( DOI )

  30. R. Fujimoto, K. Mitsuda, N. Y. Yamasaki, N. Iyomoto, T. Oshima, Y. Takei, K. Futamoto, T. Ichitsubo, T. Fujimori, K. Yoshida, Y. Ishisaki, U. Morita, T. Koga, K. Shinozaki, K. Sato, N. Takai, T. Ohashi, H. Kudo, H. Sato, T. Arakawa, H. Kobayashi, T. Izumi , S. Ohtsuka, K. Mori, S. Shoji, T. Osaka, T. Homma, Y. Kuroda, M. Onishi, M. Goto, F. Beppu, T. Tanaka, T. Morooka, S. Nakayama, K. Chinone: TES Microcalorimeter development for future Japanese X-ray astronomy missions. Nuclear Instruments and Methods in Physics Research Section A. 2004.04; 520 (1-3): 431-434. ( DOI )

  31. Kai M, Irie M, Okutsu T, Inoue K, Ogonuki N, Miki H, Yokoyama M, Migishima R, Muguruma K, Fujimura H, Kohda T, Ogura A, Kaneko-Ishino T, Ishino F: The novel dominant mutation Dspd leads to a severe spermiogenesis defect in mice. Biology of Reproduction. 2004.04; 70 (4): 1213-1221.

  32. Tamamura H, Mizumoto M, Hiramatsu K, Kusano S, Terakubo S, Yamamoto N, Trent JO, Wang Z, Peiper SC, Nakashima H, Otaka A, Fujii N: Topochemical exploration of potent compounds using retro-enantiomer libraries of cyclic pentapeptides. Org Biomol Chem. 2004.04; 2 (8): 1255-1257. ( PubMed , DOI )

  33. Mitsubayashi K*, Kubotera Y, Yano K, Hashimoto Y, Kon T, Nakakura S, Nishi Y, Endo H: Trimethylamine biosensor with flavin-containing monooxygenase type 3 (FMO3) for fish-freshness analysis. Sensors and Actuators B. 2004.03; 103 463-467.

  34. Hosoya T, Hiramatsu T, Ikemoto T, Nakanishi M, Aoyama H, Hosoya A, Iwata T, Maruyama K, Endo M, Suzuki M: Novel bifunctional probe for radioisotope-free photoaffinity labeling: compact structure comprised of photospecific ligand ligation and detectable tag anchoring units. Org Biomol Chem. 2004.03; 2 (5): 637-641. ( PubMed , DOI )

  35. Hirai H, Adachi T, Tsubata T: Involvement of cell cycle progression in survival signaling through CD40 in the B-lymphocyte line WEHI-231. Cell Death Differ. 2004.03; 11 (3): 261-269. ( PubMed , DOI )

  36. Otaka A, Watanabe J, Yukimasa A, Sasaki Y, Watanabe H, Kinoshita T, Oishi S, Tamamura H, Fujii N: SmI2-mediated reduction of gamma,gamma-difluoro-alpha,beta-enoates with application to the synthesis of functionalized (Z)-fluoroalkene-type dipeptide isosteres. J Org Chem. 2004.03; 69 (5): 1634-1645. ( PubMed , DOI )

  37. Ohkawara B, Shirakabe K, Hyodo-Miura J, Matsuo R, Ueno N, Matsumoto K, Shibuya H: Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction. Genes Dev. 2004.02; 18 (4): 381-386. ( PubMed , DOI )

  38. A Matsumoto, T Kurata, D Shiino, K Kataoka: Swelling and shrinking kinetics of totally synthetic, glucose-responsive polymer gel bearing phenylborate derivative as a glucose-sensing moiety MACROMOLECULES. 2004.02; 37 (4): 1502-1510. ( DOI )

  39. T.Furuzono,A.Kishida,J.Tanaka: Nano-scaled hydroxyapatite/polymer composite I. Coating of sintered hydroxyapatite particles on poly(gannma-methyacryloxypropyl trimethoxysilane)-grafted silk fibroin fibers through chemical bonding Journal of Materials Science: Materials in Medicine. 2004.01; 15 (1): 19-23. ( DOI )

  40. Hosoya T, Wakao M, Kondo Y, Doi H, Suzuki M: Rapid methylation of terminal acetylenes by the Stille coupling of methyl iodide with alkynyltributylstannanes: a general protocol potentially useful for the synthesis of short-lived 11CH3-labeled PET tracers with a 1-propynyl group. Org Biomol Chem. 2004.01; 2 (1): 24-27. ( PubMed , DOI )

  41. Mori T, Doi R, Koizumi M, Toyoda E, Ito D, Kami K, Masui T, Fujimoto K, Tamamura H, Hiramatsu K, Fujii N, Imamura M: CXCR4 antagonist inhibits stromal cell-derived factor 1-induced migration and invasion of human pancreatic cancer. Mol Cancer Ther. 2004.01; 3 (1): 29-37. ( PubMed )

  42. Tamamura H, Sigano DM, Lewin NE, Blumberg PM, Marquez VE: Conformationally constrained analogues of diacylglycerol. 20. The search for an elusive binding site on protein kinase C through relocation of the carbonyl pharmacophore along the sn-1 side chain of 1,2-diacylglycerol lactones. J Med Chem. 2004.01; 47 (3): 644-655. ( PubMed , DOI )

  43. Fujisawa S, Atsumi T, Kadoma Y, Ishihara M, Ito S, Yokoe I: Kinetic radical scavenging activity and cytotoxicity of 2-methoxy- and 2-t-butyl-substituted phenols and their dimers. Anticancer Res. 2004; 24 (5A): 3019-26.

  44. Onkol T, Yildirim E, Erol K, Ito S, Sahin MF.: Synthesis and antinociceptive activity of (5-chloro-2(3H)-benzothiazolon-3-yl)propanamide derivatives. Archiv der Pharmazie. 2004; 337 475-481.

  45. Onkol T, Sahin MF, Yildirim E, Erol K, Ito S: Synthesis and antinociceptive activity of (5-chloro-2(3H)-benzooxazolon-3-yl)propanamide derivatives. Arch Pharm Research. 2004; 27 (11): 1086-1092.

  46. Suzuki M, Doi H, Hosoya T, Långström B, Watanabe Y.: Rapid methylation on carbon frameworks leading to the synthesis of a PET tracer capable of imaging a novel CNS-type prostacyclin receptor in living human brain. Trends Anal Chem. 2004; 23 (8): 595-607. ( DOI )

  47. Umehara S, Yasuda K: 大腸菌における運動エネルギー消費と成長エネルギー消費の履歴現象 伝熱. 2004; 43 (180): 28-32.

  48. Ayano S, Noma S, Taguchi H, Yoshida M, Yasuda K: On-chip single-cell observation assay for propagation dynamics of yeast Sup35 prionlike proteins. Jpn J Appl Phys. 2004; 43 (11A): L1429-L1432.

  49. Sugio Y, Kojima K, Moriguchi H, Takahashi K, Kaneko T, Yasuda K: An agar-based on-chip neural-cell cultivation system for stepwise control of network pattern generation during cultivation. Sens & Actuat B . 2004; 99 (1): 156-162.

  50. Hattori A, Moriguchi H, Ishiwata S, Yasuda K: A 1480-nm/1064-nm dual wavelength photo-thermal etching system for non-contact three-dimensional microstructure generation into agar microculture chip. Sens & Actuat B. 2004; 100　 (3): 455-462.

  51. Umehara S, Hattori A, Wakamoto Y, Yasuda K: Simultaneous measurement of growth and movement of cells exploiting on-chip single-cell cultivation assay, Jpn J Appl Phys. 2004; 43 (3): 1214-1217.

  52. Suzuki I, Sugio Y, Moriguchi H, Hattori A, Yasuda K, Jimbo Y: Pattern modification of a neuronal network for individual-cell-based electrophysiological measurement using photothermal etching of an agarose architecture with a multielectrode array. IEE Proc.-Nanobiotechnol. 2004; 151 (3): 116-121.

  53. Suzuki I, Sugio Y, Jimbo Y, Yasuda K: Individual-cell-based electrophysiological measurement of a topographically controlled neuronal network pattern using agarose architecture with a multi-electrode array. Jpn J Appl Phys. 2004; 43 (3B): L403-L406.

  54. Sato N, Nakayama M, Arai K: Fluctuation of chromatin unfolding associated with variation in the level of gene expression Genes Cells. 2004; 9 (7): 619-630. ( PubMed , DOI )

  55. Mitsuko Takenaga, Hirokazu Tamamura, Kenichi Hiramatsu, Natsumi Nakamura, Yoko Yamaguchi, Aki Kitagawa, Shinichi Kawai, Hideki Nakashima, Nobutaka Fujii & Rie Igarashi: A Single Treatment with Microcapsules Containing a CXCR4 Antagonist Suppresses Pulmonary Metastasis of Murine Melanoma. Biochem. Biophys. Res. Commun.. 2004; 320 (1): 226-232.

  1. T.Serizawa、M.Yamaguchi、A.Kishida、M.Akashi: Alternating gene expression in fibroblasts adhering to multilayers of chitosan and dextran sulfate Journal of Biomedical Materials Research Part A. 2003.12; 67A (3): 1060-1063. ( DOI )

  2. T.Furuzono,M.Iwasaki,S.Yasuda,A.Korematsu,T.Yoshioka,S.Ito,A.Kishida: Photoreactivity and cell adhesiveness of amino-group-modified titanium dioxide nano-particles on silicone substrate coated by covalent linkage. Journal of Materials Science Letters. 2003.12; 22 (24): 1737-1740. ( DOI )

  3. A.Kishida: A site-specific polymeric drug carrier for renal disease treatment Trends in Pharmaceutical Science. 2003.12; 24 (12): 611-613.

  4. *Kohji MITSUBAYASHI, Yoko MIYOSHI,* Toshifumi TAKEUCHI* and Isao KARUBE: Electric conductimetric sensor with a thin-layer structure for moisture analysis. IEEE Journal of Optoelectronic and Microelectronic Materials and Devices. 2003.12;

  5. *Kohji MITSUBAYASHI, Yuki HASHIMOTO & Takuo KON: Bio-optical gas-sensor (sniffer device) with a fiber optic oxygen sensor. IEEE Journal of Optoelectronic and Microelectronic Materials and Devices. 2003.12;

  6. Ishitani T, Takaesu G, Ninomiya-Tsuji J, Shibuya H, Gaynor RB, Matsumoto K: Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling. EMBO J. 2003.12; 22 (23): 6277-6288. ( PubMed , DOI )

  7. A.Matsuda、T.Furuzono、D.Walsh、A.Kishida、J.Tanaka: Surface modification of a porous hydroxyapatite to promote bonded polymer coatings Journal of Materials Science: Materials in Medicine. 2003.11; 14 (11): 973-978. ( DOI )

  8. Trent JO, Wang ZX, Murray JL, Shao W, Tamamura H, Fujii N, Peiper SC: Lipid bilayer simulations of CXCR4 with inverse agonists and weak partial agonists. J Biol Chem. 2003.11; 278 (47): 47136-47144. ( PubMed , DOI )

  9. Tamamura H, Hiramatsu K, Mizumoto M, Ueda S, Kusano S, Terakubo S, Akamatsu M, Yamamoto N, Trent JO, Wang Z, Peiper SC, Nakashima H, Otaka A, Fujii N: Enhancement of the T140-based pharmacophores leads to the development of more potent and bio-stable CXCR4 antagonists. Org Biomol Chem. 2003.11; 1 (21): 3663-3669. ( PubMed )

  10. Tamamura H, Hiramatsu K, Kusano S, Terakubo S, Yamamoto N, Trent JO, Wang Z, Peiper SC, Nakashima H, Otaka A, Fujii N: Synthesis of potent CXCR4 inhibitors possessing low cytotoxicity and improved biostability based on T140 derivatives. Org Biomol Chem. 2003.11; 1 (21): 3656-3662. ( PubMed )

  11. Oonuma T, Morimatsu M, Nakagawa T, Uyama R, Sasaki N, Nakaichi M, Tamamura H, Fujii N, Hashimoto S, Yamamura H, Syuto B: Role of CXCR4 and SDF-1 in mammary tumor metastasis in the cat. J Vet Med Sci. 2003.10; 65 (10): 1069-1073. ( PubMed )

  12. A.Korematsu、T.Furuzono、A.Kishida: Synthesis of a novel block copolymer containing aromatic polyamide and fluoroethylene segments Journal of Polymer Science Part A: Polymer Chemistry . 2003.09; 41 (18): 2840-2845. ( DOI )

  13. Matsumoto A, Ikeda S, Harada A, Kataoka K: Glucose-responsive polymer bearing a novel phenylborate derivative as a glucose-sensing moiety operating at physiological pH conditions. Biomacromolecules. 2003.09; 4 (5): 1410-1416. ( PubMed , DOI )

  14. *Kohji Mitsubayashi, Hirokazu Amagai, Hidenori Watanabe, Yoshinori Nakayama: Bioelectronic sniffer with a diaphragm flow-cell for acetaldehyde vapor Sensors and Actuators B. 2003.09; 95 303-308.

  15. Hokazono Y, Adachi T, Wabl M, Tada N, Amagasa T, Tsubata T: Inhibitory coreceptors activated by antigens but not by anti-Ig heavy chain antibodies install requirement of costimulation through CD40 for survival and proliferation of B cells. J Immunol. 2003.08; 171 (4): 1835-1843. ( PubMed )

  16. Hokazono Y, Adachi T, Wabl M, Tada N, Amagasa T, Tsubata T: Inhibitory coreceptors activated by antigens but not by anti-Ig heavy chain antibodies install requirement of costimulation through CD40 for survival and proliferation of B cells JOURNAL OF IMMUNOLOGY. 2003.08; 171 (4): 1835-1843.

  17. Yamada M, Ohkawara B, Ichimura N, Hyodo-Miura J, Urushiyama S, Shirakabe K, Shibuya H: Negative regulation of Wnt signalling by HMG2L1, a novel NLK-binding protein. Genes Cells. 2003.08; 8 (8): 677-684. ( PubMed )

  18. Tamamura H, Hori A, Kanzaki N, Hiramatsu K, Mizumoto M, Nakashima H, Yamamoto N, Otaka A, Fujii N: T140 analogs as CXCR4 antagonists identified as anti-metastatic agents in the treatment of breast cancer. FEBS Lett. 2003.08; 550 (1-3): 79-83. ( PubMed )

  19. Otaka A, Yukimasa A, Watanabe J, Sasaki Y, Oishi S, Tamamura H, Fujii N: Application of samarium diiodide (SmI2)-induced reduction of gamma-acetoxy-alpha,beta-enoates with alpha-specific kinetic electrophilic trapping for the synthesis of amino acid derivatives. Chem Commun (Camb). 2003.08; (15): 1834-1835. ( PubMed )

  20. Matsusaki M、Kamezawa T、Shimozuru T、Kuratsu J、Kishida A、Akashi M: Novel Guglielmi Detachable Coils(GDSc) for the Treatment of Brain Aneurysms. In Vitro study of Hydroxyapatite Coating on Pt Plate as GDCs Model. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2003.07; 66B (1): 429-438. ( DOI )

  21. *Kohji Mitsubayashi, Takuo Kon, Yuki Hashimoto: Optical bio-sniffer for ethanol vapor using an oxygen-sensitive optical fiber Biosensors and Bioelectronics. 2003.07; 19 193-198.

  22. Oishi I, Suzuki H, Onishi N, Takada R, Kani S, Ohkawara B, Koshida I, Suzuki K, Yamada G, Schwabe GC, Mundlos S, Shibuya H, Takada S, Minami Y: The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway. Genes Cells. 2003.07; 8 (7): 645-654. ( PubMed )

  23. Tamamura H, Kato T, Otaka A, Fujii N: Synthesis of potent beta-secretase inhibitors containing a hydroxyethylamine dipeptide isostere and their structure-activity relationship studies. Org Biomol Chem. 2003.07; 1 (14): 2468-2473. ( PubMed )

  24. Fujii N, Oishi S, Hiramatsu K, Araki T, Ueda S, Tamamura H, Otaka A, Kusano S, Terakubo S, Nakashima H, Broach JA, Trent JO, Wang ZX, Peiper SC: Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries. Angew Chem Int Ed Engl. 2003.07; 42 (28): 3251-3253. ( PubMed , DOI )

  25. *Kohji Mitsubayashi, Yoshihiko Wakabayashi, Daisuke Murotomi, Takua Yamada, Tatsuya Kawase, Isao Karube: Wearable and flexible oxygen sensor for transcutaneous oxygen monitoring Sensors and Actuators B. 2003.06; 95 373-377.

  26. T.Furuzono、P-L. Wang、A.Korematsu、K.Miyazaki、M. Oido-Mori、Y.Kowashi、K.Ohura、J.Tanaka、A.Kishida: Physical and biological evaluations of sintered hydroxyapatite/silicone composite with covalent bonding for a percutaneous implant material Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2003.05; 65B (2): 217-226. ( DOI )

  27. *Kohji Mitsubayashi, Yoshihiko Wakabayashi, Yoshihiro Ohya, Tatsuro Endo: Optical-transparent and flexible glucose sensor with ITO electrode. Biosensors and Bioelectronics. 2003.05; 19 67-71.

  28. Yasuda T, Poole AR, Shimizu M, Nakagawa T, Julovi SM, Tamamura H, Fujii N, Nakamura T: Involvement of CD44 in induction of matrix metalloproteinases by a COOH-terminal heparin-binding fragment of fibronectin in human articular cartilage in culture. Arthritis Rheum. 2003.05; 48 (5): 1271-1280. ( PubMed , DOI )

  29. T. Homma, H. Sato, H. Kobayashi, T. Arakawa, H. Kudo, T. Osaka, S. Shoji, Y. Ishisaki, T. Oshima, N. Iyomoto, R. Fujimoto, K. Mitsuda: Sn electrodeposition process for fabricating microabsorber arrays for an X-ray microcalorimeter. Journal of Electroanalytical Chemistry. 2003.04; 559 143-148. ( DOI )

  30. Tamamura H, Koh Y, Ueda S, Sasaki Y, Yamasaki T, Aoki M, Maeda K, Watai Y, Arikuni H, Otaka A, Mitsuya H, Fujii N: Reduction of peptide character of HIV protease inhibitors that exhibit nanomolar potency against multidrug resistant HIV-1 strains. J Med Chem. 2003.04; 46 (9): 1764-1768. ( PubMed , DOI )

  31. Saijo K, Schmedt C, Su IH, Karasuyama H, Lowell CA, Reth M, Adachi T, Patke A, Santana A, Tarakhovsky A: Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development. Nat Immunol. 2003.03; 4 (3): 274-279. ( PubMed , DOI )

  32. T.Shimozuru、T.Kamezawa、J.Kuratsu、N.Sakai、I.Nagata、A.Kishida、M.Akashi、M.Matsusaki: Hydroxyapatite and bFGF coating of detachable coils for endovascular occulusion of experimental aneurysm Interventional Neuroradiology. 2003.03; 9 (1): 29-33. ( DOI )

  33. Hosoya T, Aoyama H, Ikemoto T, Kihara Y, Hiramatsu T, Endo M, Suzuki M: Dantrolene analogues revisited: general synthesis and specific functions capable of discriminating two kinds of Ca2+ release from sarcoplasmic reticulum of mouse skeletal muscle. Bioorg Med Chem. 2003.03; 11 (5): 663-673. ( PubMed )

  34. Kajiyama T, Miyahara Y, Kricka LJ, Wilding P, Graves DJ, Surrey S, Fortina P: Genotyping on a thermal gradient DNA chip Genome Res. 2003.03; 13 (3): 467-475.

  35. Suzawa M, Takada I, Yanagisawa J, Ohtake F, Ogawa S, Yamauchi T, Kadowaki T, Takeuchi Y, Shibuya H, Gotoh Y, Matsumoto K, Kato S: Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade. Nat Cell Biol. 2003.03; 5 (3): 224-230. ( PubMed , DOI )

  36. Okazaki N, Kikuno R, Ohara R, Inamoto S, Aizawa H, Yuasa S, Nakajima D, Nagase T, Ohara O, Koga H: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003.02; 10 (1): 35-48. ( PubMed )

  37. Fujii N, Nakashima H, Tamamura H: The therapeutic potential of CXCR4 antagonists in the treatment of HIV. Expert Opin Investig Drugs. 2003.02; 12 (2): 185-195. ( PubMed , DOI )

  38. Ishitani T, Kishida S, Hyodo-Miura J, Ueno N, Yasuda J, Waterman M, Shibuya H, Moon RT, Ninomiya-Tsuji J, Matsumoto K: The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling. Mol Cell Biol. 2003.01; 23 (1): 131-139. ( PubMed )

  39. Yamaguchi T, Nomura H, Matsunaga K, Ito S, Takata J, Karube Y.: The Behavior of Dihydropyrazine with DNA Strand-Breakage Activity in vivo Biological & Pharmaceutical Bulletin. 2003; 26 1523-1527.

  40. Mibu N, Yukawa M, Kashige N, Iwase Y, Goto Y, Miake F, Yamaguchi T, Ito S, Sumoto K: The Behavior of Dihydropyrazine with DNA Strand-Breakage Activity in vivo. CHEM PHARM BULL. 2003; 51 (1): 27-31.

  41. Furukohri A, Sato N, Masai H, Arai K, Sugino A, Waga S: Identification and characterization of a Xenopus homolog of Dbf4, a regulatory subunit of the Cdc7 protein kinase required for the initiation of DNA replication J Biochem. 2003; 134 (3): 447-457. ( PubMed )

  42. Sato N, Sato M, Nakayama M, Saitoh R, Arai K, Masai H: Cell cycle regulation of chromatin binding and nuclear localization of human Cdc7-ASK kinase complex Genes Cells. 2003; 8 (5): 451-463. ( PubMed )

  43. S.Sakuma、R.Sudo、N.Suzuki、H.Kikuchi、H.Takamori、T.Sato、Y.Minamitake、Y.Hayashi、O.Sugita、K.Hiwatari、A.Kishida、M.Akashi: Human Calcitonin delivered orally by means of nanoparticles composed of novel graft copolymers Journal of Dispersion Science and Technology . 2003; 24 (3-4): 623-632. ( DOI )

  44. Takahashi K, Matsumura K, Yasuda K: On-chip microcultivation chamber for swimming cells using visualized poly(dimetylsiloxane) valve. Jpn J Appl Phys. 2003; 42 (9AB): L1104 -L1107.

  45. Kojima K, Takahashi K, Kaneko T, Yasuda K: Flexible control of electrode pattern on cultivation chamber during cultivation of cells using non-destructive optical etching. Jpn J Appl Phys. 2003; 42 (8A): L980 -L982.

  46. Kojima K, Moriguchi H, Hattori A, Kaneko T, Yasuda K: Two-dimensional Network Formation of Cardiac Myocytes in Agar Microculture Chip with 1480-nm Infrared Laser Photo-thermal Etching. Lab Chip. 2003; 3 292-296.

  47. Umehara S, Wakamoto Y, Inoue I, Yasuda K: On-chip single-cell microcultivation assay for monitoring environmental effects on isolated cells, Biochem Biophys Res Commun. 2003; 305 534-540.

  48. Matsumura K, Yagi T, Yasuda K: Role of Timer and Sizer in Regulation of Chlamydomonas Cell Cycle, Biochem Biophys Res Commun. 2003; 306 1042-1049.

  49. Moriguchi H, Takahashi K, Sugio Y, Wakamoto Y, Inoue I, Jimbo Y, Yasuda K: On chip neural cell cultivation using agarose-microchamber array constructed by photo-thermal etching method. Electrical Engineering in Japan. 2003; 146 (2): 37-42.

  50. Wakamoto Y, Umehara S, Matsumura K, Inoue I, Yasuda K: Development of Non-Destructive, Non-contact Single-Cell Based Differential Cell Assay using On-chip Microcultivation and Optical Tweezers, Sens & Actuat B. 2003; 96 (3): 693-700.

  51. Matsumura K, Yagi T, Yasuda K: Differential analysis of cell cycle stability in Chlamydomonas using on-chip single-cell cultivation system, Jpn J Appl Phys. 2003; 42 (7A): L784-L787.

  52. Hattori A, Umehara S, Wakamoto Y, Yasuda K: Measurement of incident angle dependence of swimming bacterium reflection using on-chip single-cell cultivation assay, Jpn J Appl Phys. 2003; 42 (7B): L873-L875.

  1. Wakabayashi C, Adachi T, Wienands R, Tsubata T: A distinct signaling pathway used by the IgG-containing B cell antigen receptor SCIENCE. 2002.12; 298 (5602): 2392-2395.

  2. Komatsu Y, Shibuya H, Takeda N, Ninomiya-Tsuji J, Yasui T, Miyado K, Sekimoto T, Ueno N, Matsumoto K, Yamada G: Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis. Mech Dev. 2002.12; 119 (2): 239-249. ( PubMed )

  3. Wakabayashi C, Adachi T, Wienands J, Tsubata T: A distinct signaling pathway used by the IgG-containing B cell antigen receptor. Science. 2002.12; 298 (5602): 2392-2395. ( PubMed , DOI )

  4. S.Fukuhara、S.Tomita、T.Nakatani、A.Kishida、T.Morisaki、C.Yutani、S.Kitamura: Comparison of cell labelling procedures for bone marrow cell transplantation to treat heart failure: long-term quantitative analysis Transplantation Proceedings. 2002.11; 34 (7): 2718-2721. ( DOI )

  5. Hosoya T, Aoyama H, Ikemoto T, Hiramatsu T, Kihara Y, Endo M, Suzuki M: [(125)I]-N-[(3-azido-5-iodo)benzyl]dantrolene and [(125)I]-N-[[3-iodo-5-(3-trifluoromethyl-3H-diazirin-3-yl)]benzyl]dantrolene: photoaffinity probes specific for the physiological Ca(2+) release from sarcoplasmic reticulum of skeletal muscle. Bioorg Med Chem Lett. 2002.11; 12 (22): 3263-3265. ( PubMed )

  6. Shigeki Yuasa, Mitsunari Nakajima, Hidenori Aizawa, Naruhiko Sahara, Ken-Ichi Koizumi, Tsuyoshi Sakai, Mihoko Usami, Shin-Ichiro Kobayashi, Hidehito Kuroyanagi, Hiroshi Mori, Haruhiko Koseki, Takuji Shirasawa: Impaired cell cycle control of neuronal precursor cells in the neocortical primordium of presenilin-1-deficient mice. J. Neurosci. Res.. 2002.11; 70 (3): 501-513. ( PubMed , DOI )

  7. Miyahara Yuji, Abe Kazuaki, Inazu Takahiko: "Molecular" molecular sieves: lid-free decamethylcucurbit[5]uril absorbs and desorbs gases selectively. Angew Chem Int Ed Engl. 2002.08; 41 (16): 3020-3023. ( PubMed , DOI )

  8. Oishi S, Kamano T, Niida A, Odagaki Y, Hamanaka N, Yamamoto M, Ajito K, Tamamura H, Otaka A, Fujii N: Diastereoselective synthesis of new psi[(E)-CH=CMe]- and psi[(Z)-CH=CMe]-type alkene dipeptide isosteres by organocopper reagents and application to conformationally restricted cyclic RGD peptidomimetics. J Org Chem. 2002.08; 67 (17): 6162-6173. ( PubMed )

  9. Otaka A, Nakamura M, Nameki D, Kodama E, Uchiyama S, Nakamura S, Nakano H, Tamamura H, Kobayashi Y, Matsuoka M, Fujii N: Remodeling of gp41-C34 peptide leads to highly effective inhibitors of the fusion of HIV-1 with target cells. Angew Chem Int Ed Engl. 2002.08; 41 (16): 2937-2940. ( PubMed , DOI )

  10. Otaka A, Katagiri F, Kinoshita T, Odagaki Y, Oishi S, Tamamura H, Hamanaka N, Fujii N: Regio- and stereoselective synthesis of (E)-alkene trans-Xaa-Pro dipeptide mimetics utilizing organocopper-mediated anti-S(N)2' reactions. J Org Chem. 2002.08; 67 (17): 6152-6161. ( PubMed )

  11. Zhang WB, Navenot JM, Haribabu B, Tamamura H, Hiramatu K, Omagari A, Pei G, Manfredi JP, Fujii N, Broach JR, Peiper SC: A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists. J Biol Chem. 2002.07; 277 (27): 24515-24521. ( PubMed , DOI )

  12. S.Sakuma、N.Suzuki、R.Sudo、K.Hiwatari、A.Kishida、M.Akashi: Optimized chemical structure of nanoparticles as carriers for oral delivery of salmon calcitonin International Journal of Pharmaceutics. 2002.06; 239 (1-2): 185-195. ( DOI )

  13. *Kohji MITSUBAYASHI, Yuki HASHIMOTO: Bioelectronic nose for methyl mercaptan vapor using xenobiotic metabolizing enzyme: flavin-containing monooxygenase. Sensors and Actuators B. 2002.05; 83 35-40.

  14. Hyodo-Miura J, Urushiyama S, Nagai S, Nishita M, Ueno N, Shibuya H: Involvement of NLK and Sox11 in neural induction in Xenopus development. Genes Cells. 2002.05; 7 (5): 487-496. ( PubMed )

  15. Tamamura H, Omagari A, Hiramatsu K, Oishi S, Habashita H, Kanamoto T, Gotoh K, Yamamoto N, Nakashima H, Otaka A, Fujii N: Certification of the critical importance of L-3-(2-naphthyl)alanine at position 3 of a specific CXCR4 inhibitor, T140, leads to an exploratory performance of its downsizing study. Bioorg Med Chem. 2002.05; 10 (5): 1417-1426. ( PubMed )

  16. Ikenoya M, Hidaka H, Hosoya T, Suzuki M, Yamamoto N, Sasaki Y: Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor. J Neurochem. 2002.04; 81 (1): 9-16. ( PubMed )

  17. Oishi S, Kamano T, Niida A, Odagaki Y, Tamamura H, Otaka A, Hamanaka N, Fujii N: Diastereoselective synthesis of psi[(E)-CH=CMe]- and psi[(Z)-CH=CMe]-type dipeptide isosteres by organocopper-mediated anti-S(N)2' reaction. Org Lett. 2002.04; 4 (7): 1051-1054. ( PubMed )

  18. Oishi S, Niida A, Kamano T, Odagaki Y, Tamamura H, Otaka A, Hamanaka N, Fujii N: Diastereoselective synthesis of psi[(E)-CMe=CH]- and psi[(E)-CMe=CMe]- type dipeptide isosteres based on organocopper-mediated anti-S(N)2' reaction. Org Lett. 2002.04; 4 (7): 1055-1058. ( PubMed )

  19. *Kohji MITSUBAYASHI, Yuki HASHIMOTO: Bioelectronic sniffer device for trimethylamine vapor using flavin containing monooxygenase. IEEE Sensors Journal. 2002.03; 2 (3): 133-139.

  20. Tamamura H, Hiramatsu K, Miyamoto K, Omagari A, Oishi S, Nakashima H, Yamamoto N, Kuroda Y, Nakagawa T, Otaka A, Fujii N: Synthesis and evaluation of pseudopeptide analogues of a specific CXCR4 inhibitor, T140: the insertion of an (E)-alkene dipeptide isostere into the betaII'-turn moiety. Bioorg Med Chem Lett. 2002.03; 12 (6): 923-928. ( PubMed )

  21. M.Matsusaki、T.Serizawa、A.Kishida、T.Endo、M.Akashi: Novel functional biodegradable polymer: Synthesis and anticoagulant activity of poly(g-glutamic acid) sulfonate (g-PGA-sulfonate) Bioconjugate Chemistry . 2002.01; 13 (1): 23-28. ( DOI )

  22. Takamatsu H, Tsukada H, Watanabe Y, Cui Y, Kataoka Y, Hosoya T, Suzuki M, Watanabe Y: Specific ligand for a central type prostacyclin receptor attenuates neuronal damage in a rat model of focal cerebral ischemia. Brain Res. 2002.01; 925 (2): 176-182. ( PubMed )

  23. *Yuki Kaneko, Yuki Hashimoto, Kohji Mitsubayash: A bioelectronic nose for ammonia vapor. Journal of Advanced Science. 2002.01; 14 (1,2): p21-22.

  24. *Yoshihiko Wakabayashi, Kohji Mitsubayashi, Yoshiko Taya, Yoko Nomura: A telemetry system with mobile phones for monitoring human physical indices. Journal of Advanced Science. 2002.01; 14 (1,2): 35-36.

  25. *Hiroyuki Matsunaga, Satoshi Toda, Kohji Mitsubayashi: A stick-type enzyme electrode for a breath alcohol analysis. Journal of Advanced Science. 2002.01; 14 (1,2): 19-20.

  26. *Yoshihiro Oya, Tatsuro Endo, Kohji Mitsubayashi: A film-type glucose sensor with optical transparency. Journal of Advanced Science. 2002.01; 14 (1,2): 33-34.

  27. *Kazuhisa Yano, Yohei Kubotera, Takeshi Yoshikawa, Yuki Hashimoto, Kohji Mitsubayashi, Hideaki Endo, Yoshitake Nishi: Developent of a freshness sensor with flavin-containing monooxygenase. Journal of Advanced Science. 2002.01; 14 (1,2): 93-94.

  28. *Takuo Kon, Yuki Hashimoto, Kohji Kohji Mitsubayashi: A bio-optical nose for alcohol vapor. Journal of Advanced Science. 2002.01; 14 (1,2): 87-88.

  29. Yamaguchi T, Ito S, Mibu N, Sumoto K.: Reaction of 2,3-butanedione with propylenediamine observed by H-1-NMR spectroscopy. HETEROCYCLES. 2002; 57 (1): 11-16.

  30. Hamura T, Hosoya T, Yamaguchi H, Kuriyama Y, Tanabe M, Miyamoto M, Yasui Y, Matsumoto T, Suzuki K.: Facile access to versatile polyaromatic building blocks: selectively protected benzocyclobutenedione derivatives via regioselective [2 + 2] cycloaddition of α-alkoxybenzyne and ketene silyl acetal. Helv Chim Acta. 2002; 85 (11): 3589-3604. ( DOI )

  31. Moriguchi H, Wakamoto Y, Sugio Y, Takahashi K, Inoue I Yasuda K: An agar-microchamber cell-cultivation system: flexible change of microchamber shapes during cultivation by photo-thermal etching. Lab Chip. 2002; 2 125-130.

  32. 森口裕之、高橋一憲、杉尾嘉宏、若本祐一、井之上一平、神保泰彦、安田賢二　: 集束光加熱エッチング法によって加工したアガロースマイクロチャンバアレイを用いた神経細胞の培養 電気学会論文誌. 2002; 122 (C): 1453-1458.

  33. Takakura K, Toyota T, Yamada K, Ishimaru M, Yasuda K, T. Sugawara: Morphological Change of Giant Vesicles Triggered by Dehydrocondensation Reaction Chem Lett. 2002; 31 (3): 404-405.

  34. Moriguchi H, Takahashi K, Kaneko T, Yasuda K: On-chip agarose-microchamber (AMC) array cell-cultivation system for topographical control of neural network Proceedings of Micro Total Analysis System Symposium 2002. 2002; 1 13-15.

  35. Hirokazu Tamamura, Tadakazu Hori, Akira Otaka & Nobutaka Fujii: Efficient Stereoselective Synthesis of Peptidomimetics Containing Hydroxyethylamine Dipeptide Isosteres Utilizing the Aza-Payne Rearrangement and O, N-Acyl Transfer Reactions. J. Chem. Soc., Perkin Trans.. 2002; 1 (2002(5)): 577-580.

  36. 高橋一憲、杉尾嘉宏、森口裕之、神保泰彦、安田賢二　: 光硬化性樹脂SU-8と半透膜を用いた神経細胞長期培養用多電極刺激計測マイクロチャンバの試作 電気学会論文誌. 2002; 122 (C): 1447-1452.

  37. Yamada M, Sato N, Taniyama C, Ohtani K, Arai K, Masai H: A 63-base pair DNA segment containing an Sp1 site but not a canonical E2F site can confer growth-dependent and E2F-mediated transcriptional stimulation of the human ASK gene encoding the regulatory subunit for human Cdc7-related kinase J Biol Chem. 2002; 277 (31): 27668-27681. ( PubMed , DOI )

  38. Shinya Oishi, Ayumu Niida, Takae Kamano, Yoshihisa Miwa, Tooru Taga, Yoshihiko Odagaki, Nobuyuki Hamanaka, Mikio Yamamoto, Keiichi Ajito, Hirokazu Tamamura, Akira Otaka & Nobutaka Fujii: Regio- and Stereoselective Ring-opening of Chiral 1,3-Oxazolidin-2-one Derivatives by Organocopper Reagents Provides Novel Access to Di-, tri- and tetra-substituted Alkene Dipeptide Isosteres. J. Chem. Soc., Perkin Trans.. 2002; 1 (2002(15)): 1786-1793.

  1. M.Matsusaki、A.Kishida、N.Stainton、C.Ansell、M.Akashi: Synthesis and characterization of novel biodegradable polymers composed of hydroxycinnamic acid and D,L-lactic acid Journal of Applied Polymer Science . 2001.12; 82 (10): 2357-2364. ( DOI )

  2. T. Shimozuru、T. Kamezawa、J. Kuratsu、N. Sakai、I. Nagata、A. Kishida、M. Akashi、M. Matsusaki: Hydroxyapatite coating of detachable coils for endovascular occulusion of experimental aneurysm Interventional Neuroradiology. 2001.12; 7 (1): 105-110. ( DOI )

  3. Yanagisawa M, Nakashima K, Takeda K, Ochiai W, Takizawa T, Ueno M, Takizawa M, Shibuya H, Taga T: Inhibition of BMP2-induced, TAK1 kinase-mediated neurite outgrowth by Smad6 and Smad7. Genes Cells. 2001.12; 6 (12): 1091-1099. ( PubMed )

  4. Tamamura H: [Development of selective antagonists against an HIV second receptor] Yakugaku Zasshi. 2001.11; 121 (11): 781-792. ( PubMed )

  5. Ikemoto T, Hosoya T, Aoyama H, Kihara Y, Suzuki M, Endo M: Effects of dantrolene and its derivatives on Ca(2+) release from the sarcoplasmic reticulum of mouse skeletal muscle fibres. Br J Pharmacol. 2001.10; 134 (4): 729-736. ( PubMed , DOI )

  6. Shirakabe K, Terasawa K, Miyama K, Shibuya H, Nishida E: Regulation of the activity of the transcription factor Runx2 by two homeobox proteins, Msx2 and Dlx5. Genes Cells. 2001.10; 6 (10): 851-856. ( PubMed )

  7. Fujii N, Tamamura H: Peptide-lead CXCR4 antagonists with high anti-HIV activity. Curr Opin Investig Drugs. 2001.09; 2 (9): 1198-1202. ( PubMed )

  8. K.Hiwatari、T.Serizawa、F.Seto、A.Kishida、Y.Muraoka、M.Akashi: Graft Copolymers Having Hydrophobic Backbone and Hydrophilic Branches. XXXIV. Fabrication and Control of Honeycomb Structure Prepared from Amphiphilic Graft Copolymers Polymer Journal . 2001.09; 33 (9): 669-675. ( DOI )

  9. Tamamura H, Omagari A, Hiramatsu K, Kanamoto T, Gotoh K, Kanbara K, Yamamoto N, Nakashima H, Otaka A, Fujii N: Synthesis and evaluation of bifunctional anti-HIV agents based on specific CXCR4 antagonists-AZT conjugation. Bioorg Med Chem. 2001.08; 9 (8): 2179-2187. ( PubMed )

  10. Adachi T, Wienands J, Wakabayashi C, Yakura H, Reth M, Tsubata T: SHP-1 requires inhibitory co-receptors to down-modulate B cell antigen receptor-mediated phosphorylation of cellular substrates. J Biol Chem. 2001.07; 276 (28): 26648-26655. ( PubMed , DOI )

  11. *Kohji MITSUBAYASHI, Tatsuro ENDO, Satoshi SASAKI, Isao KARUBE: Optical-Transparent Oxygen Sensor with a Thinner Membrane Structure. Analytical Science. 2001.07; 17 (SUPPLEMENT): i773-i776.

  12. Adachi T, Wienands J, Wakabayashi C, Yakura H, Reth M, Tsubata T: SHP-1 requires inhibitory co-receptors to down-modulate B cell antigen receptor-mediated phosphorylation of cellular substrates JOURNAL OF BIOLOGICAL CHEMISTRY. 2001.07; 276 (28): 26648-26655.

  13. Sugawara K, Morita K, Ueno N, Shibuya H: BIP, a BRAM-interacting protein involved in TGF-beta signalling, regulates body length in Caenorhabditis elegans. Genes Cells. 2001.07; 6 (7): 599-606. ( PubMed )

  14. Tamamura H, Omagari A, Hiramatsu K, Gotoh K, Kanamoto T, Xu Y, Kodama E, Matsuoka M, Hattori T, Yamamoto N, Nakashima H, Otaka A, Fujii N: Development of specific CXCR4 inhibitors possessing high selectivity indexes as well as complete stability in serum based on an anti-HIV peptide T140. Bioorg Med Chem Lett. 2001.07; 11 (14): 1897-1902. ( PubMed )

  15. Higo J, Ito N, Kuroda M, Ono S, Nakajima N, Nakamura H: Energy landscape of a peptide consisting of alpha-helix, 3(10)-helix, beta-turn, beta-hairpin, and other disordered conformations. Protein Sci. 2001.06; 10 (6): 1160-1171. ( PubMed , DOI )

  16. *Tatsuro ENDO, Kohji MITSUBAYASHI: Study of a film-type oxygen sensor with optical transparency. Journal of Advanced Science. 2001.06; 13 (1,2): 27-28.

  17. Ohnishi J, Ohnishi E, Jin M, Hirano W, Nakane D, Matsui H, Kimura A, Sawa H, Nakayama K, Shibuya H, Nagashima K, Takahashi T: Cloning and characterization of a rat ortholog of MMP-23 (matrix metalloproteinase-23), a unique type of membrane-anchored matrix metalloproteinase and conditioned switching of its expression during the ovarian follicular development. Mol Endocrinol. 2001.05; 15 (5): 747-764. ( PubMed )

  18. Morita K, Shimizu M, Shibuya H, Ueno N: A DAF-1-binding protein BRA-1 is a negative regulator of DAF-7 TGF-beta signaling. Proc Natl Acad Sci U S A. 2001.05; 98 (11): 6284-6288. ( PubMed , DOI )

  19. *Hidenori WATANABE, Kohji MITSUBAYASHI: Gas-phase biosensor for aldehyde chemicals. Journal of Advanced Science. 2001.04; 13 (1,2): 29-30.

  20. S.Kato、T.Matsuyama、T.Serizawa、A.Kishida、M.Akashi: HSP47 and collagen mRNA expression in L929 cells adhered to lipid films Journal of Biomaterials Science, Polymer Edition. 2001.04; 12 (2): 149-156. ( DOI )

  21. *Kohji MITSUBAYASHI, Yuki HASHIMOTO, Yoshihiro NAKAYAMA, Hidenori WATANABE, Thierry Montesino, Thierry NOGUER, Jean-Louis MARTY: Gas-sensors with high selectivity using a biological catalytic system. Journal of Advanced Science. 2001.03; 12 (3): 211-216.

  22. Thierry Montesino, Thierry NOGUER, Jean-Louis MARTY, Kohji MITSUBAYASHI: Screen-printed electrodes with genetically modified cholinesterase for detection of pesticides in water-miscible organic solvent. Journal of Advanced Science. 2001.03; 12 (3): 217-222.

  23. *Yuki HASHIMOTO, Kohji MITSUBAYASHI: Pattern Recognition of Malodor Substances using a Bioelectrical Nose System. Analytical Science. 2001.03; 17 ((SUPPLEMENT),): p i1717-i1720.

  24. Gotoh K, Yoshimori M, Kanbara K, Tamamura H, Kanamoto T, Mochizuki K, Fujii N, Nakashima H: Increase of R5 HIV-1 infection and CCR5 expression in T cells treated with high concentrations of CXCR4 antagonists and SDF-1. J Infect Chemother. 2001.03; 7 (1): 28-36. ( PubMed , DOI )

  25. K.Hiwatari、Serizawa、A.Kishida、M.Akashi: Graft copolymers having hydrophobic backbone and hydrophilic branches XXXI. A DSC study of internal structures and thermophysical properties of core-corona polymeric nanospheres Polymer Journal. 2001.03; 33 (5): 424-428. ( DOI )

  26. A.Kishida、T.Matsuyama、I.Kitajima、I.Maruyama、M.Akashi: Study of cell-material interaction by estimating NF-kB activation in HeLa cells adhered onto hydrophilic substrates Biomaterials. 2001.03; 22 (6): 541-546. ( DOI )

  27. Masuda Y, Sasaki A, Shibuya H, Ueno N, Ikeda K, Watanabe K: Dlxin-1, a novel protein that binds Dlx5 and regulates its transcriptional function. J Biol Chem. 2001.02; 276 (7): 5331-5338. ( PubMed , DOI )

  28. Tamamura H, Sugioka M, Odagaki Y, Omagari A, Kan Y, Oishi S, Nakashima H, Yamamoto N, Peiper SC, Hamanaka N, Otaka A, Fujii N: Conformational study of a highly specific CXCR4 inhibitor, T140, disclosing the close proximity of its intrinsic pharmacophores associated with strong anti-HIV activity. Bioorg Med Chem Lett. 2001.02; 11 (3): 359-362. ( PubMed )

  29. T.Taguchi、Y.Muraoka、H.Matsuyama、A.Kishida、M.Akashi: Apatite coationg on hydrophilic Polymer-Grafted Poly(ethylene) Films Using an Alternate Soaking Process Biomaterials. 2001.01; 22 (1): 53-58. ( DOI )

  30. T Tsubata, C Wakabayashi, T Adachi: Regulation of B-cell antigen receptor signaling by CD72 ACTIVATING AND INHIBITORY IMMUNOGLOBULIN-LIKE RECEPTORS. 2001; 123-128.

  31. 玉村　啓和: HIV侵入の第二受容体に対する特異的拮抗剤の発見と応用に関する研究 薬学雑誌. 2001; 121 (11): 781-792.

  32. Onkol T, Ito S, Yildirim E, Erol K, Sahin MF.: Synthesis and antinociceptive activity of (2-benzazolon-3-yl)propionamide derivatives ARCH PHARM. 2001; 334 (1): 17-20.

  33. Toker G, Aslan M, Yesilada E, Memisoglu M, Ito S Comparative evaluation of the flavonoid content in officinal Tiliae flos and Turkish lime species for quality assessment J PHARMACEUT BIOMED 26 (1): 111-121 AUG 2001: Comparative evaluation of the flavonoid content in officinal Tiliae flos and Turkish lime species for quality assessment J PHARMACEUT BIOMED. 2001; 26 (1): 111-121.

  34. 岡野和宣, 陳鋼, 小原賢信, 梶山智晴, 安田賢二, 石渡信一 : DNAプローブアレイを用いたDNA断片回収. 電気学会論文誌E. 2001; 121 (E4): 181-186.

  35. Inoue I, Wakamoto Y, Yasuda K: Non-genetic Variability of Division Cycle and Growth of Isolated Individual Cells in On-chip Culture System." Proc Japan Acad. 2001; 77B 145-150.

  36. Wakamoto Y, Inoue I, Moriguchi H, Yasuda K: Analysis of single-cell differences using on-chip microculture system and optical trapping. Fresenius J Anal Chem . 2001; 371 276-281.

  37. Inoue I, Wakamoto Y, Moriguchi H, Okano K, Yasuda K: On-chip Culture System for Observation of Isolated Individual Cells. Lab chip. 2001; 1 50-55.

  38. Akira Otaka, Hideaki Watanabe, Akira Yukimasa, Shinya Oishi, Hirokazu Tamamura & Nobutaka Fujii: New Access to α-Substituted (Z)-Fluoroalkene Dipeptide Isosteres Utilizing Organocopper Reagents under 'Reduction-oxidative Alkylation (R-OA)' Conditions. Tetrahedron Lett.. 2001; 42 (2): 5443-5446.

  39. Kenji Kanbara, Setsuko Sato, Jun-ichi Tanuma, Hirokazu Tamamura, Kazuyo Gotoh, Manabu Yoshimori, Taisei Kanamoto, Motoo Kitano, Nobutaka Fujii & Hideki Nakashima: Biological and Genetic Characterization of a Human Immunodeficiency Virus Strain Resistant to CXCR4 Antagonist T134. AIDS Res. Hum. Retroviruses. 2001; 17 (7): 615-622.

  40. Shinya Oishi, Hirokazu Tamamura, Masaki Yamashita, Yoshihiko Odagaki, Nobuyuki Hamanaka, Akira Otaka & Nobutaka Fujii: Stereoselective Synthesis of a Set of Two Functionalized (E)-Alkene Dipeptide Isosteres of L-Amino Acid-L-Glu and L-Amino acid-D-Glu. J. Chem. Soc., Perkin Trans.. 2001; 1 (19): 2445-2451.

  1. Tamamura H, Omagari A, Oishi S, Kanamoto T, Yamamoto N, Peiper SC, Nakashima H, Otaka A, Fujii N: Pharmacophore identification of a specific CXCR4 inhibitor, T140, leads to development of effective anti-HIV agents with very high selectivity indexes. Bioorg Med Chem Lett. 2000.12; 10 (23): 2633-2637. ( PubMed )

  2. A.Kishida、T.Kanda、T.Furuzono、M.Akashi: Novel functional polymers: poly(dimethylsiloxane)-polyamide multiblock copolymer IX. Surface properties of blend film of aramid-silicone resins with aramid. Journal of Applied Polymer Science . 2000.12; 78 (12): 2198-2205. ( DOI )

  3. *Kohji MITSUBAYASHI, Yuki HASHIMOTO: Development of a gas-phase biosensor for trimethylamine using a flavin-containing monooxygenase 3. Electrochemistry. 2000.11; 68 (11): 901-903.

  4. A.Kishida、T.Matsuyama、M.Nakashima、T.Serizawa、K.Sugimura、M.Akashi: Study of cell-lipid film interaction by estimating heat shock proteins mRNA expression Journal Of Bioactive And Compatible Polymers . 2000.11; 15 (6): 478-488. ( DOI )

  5. Udaka K, Wiesmuller KH, Kienle S, Jung G, Tamamura H, Yamagishi H, Okumura K, Walden P, Suto T, Kawasaki T: An automated prediction of MHC class I-binding peptides based on positional scanning with peptide libraries. Immunogenetics. 2000.08; 51 (10): 816-828. ( PubMed )

  6. Miyoshi K, Otaka A, Kaneko M, Tamamura H, Fujii N: A new practical strategy for the synthesis of long-chain phosphopeptide. Chem Pharm Bull (Tokyo). 2000.08; 48 (8): 1230-1233. ( PubMed )

  7. Otaka A, Mitsuyama E, Kinoshita T, Tamamura H, Fujii N: Stereoselective synthesis of CF(2)-substituted phosphothreonine mimetics and their incorporation into peptides using newly developed deprotection procedures. J Org Chem. 2000.08; 65 (16): 4888-4899. ( PubMed )

  8. Tamamura H, Bienfait B, Nacro K, Lewin NE, Blumberg PM, Marquez VE: Conformationally constrained analogues of diacylglycerol (DAG). 17. Contrast between sn-1 and sn-2 DAG lactones in binding to protein kinase C. J Med Chem. 2000.08; 43 (17): 3209-3217. ( PubMed )

  9. T.Taguchi、A.Kishida、M.Akashi、I.Maruyama: Immobilization of Human Vascular Endothelial Growth Factor(VEGF165) onto Biomaterial: Evaluation of the Biological Activity of Immobilized VEGF165 Journal of Bioactive and Compatible Polymers. 2000.07; 15 (4): 309-320. ( DOI )

  10. Hanafusa H, Masuyama N, Kusakabe M, Shibuya H, Nishida E: The TGF-beta family member derriere is involved in regulation of the establishment of left-right asymmetry. EMBO Rep. 2000.07; 1 (1): 32-39. ( PubMed , DOI )

  11. Tago K, Nakamura T, Nishita M, Hyodo J, Nagai S, Murata Y, Adachi S, Ohwada S, Morishita Y, Shibuya H, Akiyama T: Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein. Genes Dev. 2000.07; 14 (14): 1741-1749. ( PubMed )

  12. A.Kishida、T.Taguchi、M.Akashi: Novel Surface Treatment Conferring Biocompatibility:Apatite Formation On Materials for Artificial Organs Induced by Alternate Soaking Provess The Japanese Journal of Artificial Organs　. 2000.06; 29 (2): 452-456.

  13. T.Furuzono、T.Taguchi、A.Kishida、M.Akashi、Y.Tamada: Preparation and characterization of apatite deposited on silk fabric using an alternate soaking process Journal of Biomedical Materials Research Part A. 2000.06; 50 (3): 344-352. ( DOI )

  14. Kimura N, Matsuo R, Shibuya H, Nakashima K, Taga T: BMP2-induced apoptosis is mediated by activation of the TAK1-p38 kinase pathway that is negatively regulated by Smad6. J Biol Chem. 2000.06; 275 (23): 17647-17652. ( PubMed , DOI )

  15. M.-Q.Chen、A.Kishida、T.Serizawa、M.Akashi: Nanosphere formation in copolymerization of methyl methacrylate with poly(ethylene glycol) macromonomers. Journal of Polymer Science Part A: Polymer Chemistry . 2000.05; 38 (10): 1811-1817. ( DOI )

  16. Takatsu Y, Nakamura M, Stapleton M, Danos MC, Matsumoto K, O'Connor MB, Shibuya H, Ueno N: TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development. Mol Cell Biol. 2000.05; 20 (9): 3015-3026. ( PubMed )

  17. Y. Wang、Y. Liu、K. P. Sarker、M. Nakashima、T. Serizawa、A.Kishida、M. Akashi、M. Nakata、I. Kistajima、I.Maruyama: Polymyxin B binds to anandamide and inhibits its cytotxic effect FEBS Letters. 2000.04; 470 (2): 151-155. ( DOI )

  18. S.Kato、A.Kishida、N.Hanyu、I.Maruyama、M.Akashi: Study of cellular responses to polymeric biomaterials using the differential display method Journal of Biomaterials Science, Polymer Edition. 2000.04; 11 (4): 333-340. ( DOI )

  19. Takaesu G, Kishida S, Hiyama A, Yamaguchi K, Shibuya H, Irie K, Ninomiya-Tsuji J, Matsumoto K: TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. Mol Cell. 2000.04; 5 (4): 649-658. ( PubMed )

  20. A.Kishida、M.Nakashima、N.Sakamoto、T.Serizawa、I.Maruyama、M.Akashi: Study on complex formation between recombinant human thrombomodulin fragment and thrombin using surface plasmon resonance American Journal of Hematology . 2000.03; 63 (3): 136-140. ( DOI )

  21. S.Kato、T.Akagi、K.Sugimura、A.Kishida、M.Akashi: Evaluation of Biological responses to polymeric biomaterials by RT-PCR analysis. IV. Study of c-myc, c-fos and p53 mRNA Expression Biomaterials. 2000.02; 21 (5): 521-527. ( DOI )

  22. *Yuki Hashimoto, Kohji Mitsubayashi: Study of a bioelectronic nose with a drug metabolizing system. Chemical Sensors. 2000.02; 16 (B): 52-54.

  23. Adachi T, Wakabayashi C, Nakayama T, Yakura H, Tsubata T: CD72 negatively regulates signaling through the antigen receptor of B cells JOURNAL OF IMMUNOLOGY. 2000.02; 164 (3): 1223-1229.

  24. Nishita M, Hashimoto MK, Ogata S, Laurent MN, Ueno N, Shibuya H, Cho KW: Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer. Nature. 2000.02; 403 (6771): 781-785. ( PubMed , DOI )

  25. Adachi T, Wakabayashi C, Nakayama T, Yakura H, Tsubata T: CD72 negatively regulates signaling through the antigen receptor of B cells. J Immunol. 2000.02; 164 (3): 1223-1229. ( PubMed , DOI )

  26. T.Karita、K.Imachi、T.Taguchi、A.Kishida、M.Akashi: In vitro calcification model (1): Apatite formation on segmented polyurethane containing silicone using an alternate soaking process Journal of Bioactive and Compatible Polymers. 2000.01; 15 (1): 72-84. ( DOI )

  27. Yamaguchi T, Ito S, Iwase Y, Watanabe K, Harano K.: A diamine-exchange reaction of dihydropyrazines HETEROCYCLES. 2000; 53 (8): 1677.

  28. Dogruer DS, Sahin MF, Unlu S, Ito S.: Studies on some 3(2H)-pyridazinone derivatives with antinociceptive activity ARCH PHARM. 2000; 333 (4): 79-86.

  29. Onkol T, Dogruer DS, Ito S, Sahin MF.: Synthesis and antinociceptive activity of (5-chloro-2-benzothiazolinon-3-yl)acetamide derivatives ARCH PHARM. 2000; 333 (10): 337-340.

  30. Hosoya T, Hamura T, Kuriyama Y, Miyamoto M, Matsumoto T, Suzuki K.: Silicon-Directed Regioselective [2+2] Cycloaddition of α-Alkoxybenzyne and Ketene Silyl Acetals. Synlett. 2000; (4): 520-522. ( DOI )

  31. Futagami S, Ohashi Y, Imura K, Hosoya T, Omori K, Matsumoto T, Suzuki K.: Total synthesis of ravidomycin: revision of absolute and relative stereochemistry. Tetrahedron Lett. 2000; 41 (7): 1063-1067. ( DOI )

  32. Yasuda K: Non-destractive, non-contact handling method for biomaterials in micro-chamber by ultrasound Sens & Actuat B. 2000; 64 128-135.

  33. Yasuda K, Okano K, Ishiwata S: Focal extraction of surface-bound DNA from a microchip using photo-thermal denaturation BioTechniques . 2000; 28 1006-1011.

  34. Okano K, Yasuda K, Ishiwata S: Position-specific release of DNA from a chip by using photothermal denaturation Sens & Actuat B. 2000; 64 88-94.

  35. Akira Otaka, Etsuko Mitsuyama, Hideaki Watanabe, Hirokazu Tamamura & Nobutaka Fujii: Development of New Methodology for the Synthesis of Functionalized α-Fluorophosphonates and Its Practical Application to the Preparation of Phosphopeptide Mimetics. Chem. Commun.. 2000; 1081-1082.

  36. Kakugawa K, Udaka K, Nakashima K, Inaba K, Oka Y, Sugiyama H, Tamamura H, Yamagishi H: Efficient induction of peptide-specific cytotoxic T lymphocytes by LPS-activated spleen cells. Microbiol Immunol. 2000; 44 (2): 123-133. ( PubMed )

  1. A.Kishida、T.Matsuyama、M.Nakashima、T.Serizawa、K.Sugimura、M.Akashi: Heat Shock Protein 70B mRNA Expression in L929 Cells Attached on Lipid Films Chemistry Letters . 1999.12; 28 (12): 1267-1268. ( DOI )

  2. Otomo T, Ito N, Kyogoku Y, Yamazaki T: NMR observation of selected segments in a larger protein: Central-segment isotope labeling through intein-mediated ligation BIOCHEMISTRY. 1999.12; 38 (49): 16040-16044. ( DOI )

  3. A.Kishida、F.Seto、K.Hiwatari、T.Serizawa、Y.Muraoka、M.Akashi: Large Scale Supramolecular Self-Assembly of Graft-Copolymers Prepared by Rapid Evaporation of Organic Solvents Chemistry Letters . 1999.11; 28 (11): 1221-1222. ( DOI )

  4. F.Seto、K.Tahara、A.Kishida、Y.Muraoka、M.Akashi: Novel surface modification of cellulose film by heat‐set finishing method using poly(ethylene glycol)‐coated polystyrene nanospheres Journal of Applied Polymer Science . 1999.11; 74 (6): 1516-1523. ( DOI )

  5. F.Seto、A.Kishida、Y.Muraoka、M.Akashi: Surface modification of poly(ethylene terephthalate) film by coating with poly(ethylene glycol)‐grafted polystyrene Journal of Applied Polymer Science . 1999.11; 74 (6): 1524-1530. ( DOI )

  6. Kajiyama T, Tomita H, Miyahara Y: Manipulation of micro air bubbles in a flow-through cell using US standing waves IEEJ Transactions on Sensors and Micromachines. 1999.10; 119 (10): 464-469.

  7. Nishita M, Ueno N, Shibuya H: Smad8B, a Smad8 splice variant lacking the SSXS site that inhibits Smad8-mediated signalling. Genes Cells. 1999.10; 4 (10): 583-591. ( PubMed )

  8. A.Kishida、Y.Kikunaga、M.Akashi: Synthesis and Functionality of Poly(N-vinylalkylamide) X. A Novel Aqueous Two-Phase System Based on Thermosensitive Polymers and Dextran. Journal of Applied Polymer Science . 1999.09; 73 (13): 2545-2548. ( DOI )

  9. Furuta K, Hosoya T, Tomokiyo K, Okuda S, Kuniyasu A, Nakayama H, Ishikawa T, Suzuki M: [35S]S-[5-(4-benzoylphenyl)pentyl]glutathione: a versatile radioligand targeting GS-X pumps with the ability of photoaffinity labeling. Bioorg Med Chem Lett. 1999.09; 9 (18): 2661-2666. ( PubMed )

  10. *Yoshihiro Nakayama, Yuki Hashimoto, Kohji Mitsubayashi: Development of A Gas-phase Biosensor for Aldehyde Chemicals. Chemical Sensors. 1999.09; 15 (B): 46-48.

  11. Hanafusa H, Ninomiya-Tsuji J, Masuyama N, Nishita M, Fujisawa J, Shibuya H, Matsumoto K, Nishida E: Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression. J Biol Chem. 1999.09; 274 (38): 27161-27167. ( PubMed )

  12. Murakami T, Zhang TY, Koyanagi Y, Tanaka Y, Kim J, Suzuki Y, Minoguchi S, Tamamura H, Waki M, Matsumoto A, Fujii N, Shida H, Hoxie JA, Peiper SC, Yamamoto N: Inhibitory mechanism of the CXCR4 antagonist T22 against human immunodeficiency virus type 1 infection. J Virol. 1999.09; 73 (9): 7489-7496. ( PubMed )

  13. T.Taguchi、A.Kishida、M.Akashi: Apatite Formation on/in hydrogels using a novel alternate soaking process(III): Effect of physico-chemical factors on apatite formation on/in poly(vinyl alcohol) hydrogel matrix. Journal of Biomaterials Science, Polymer Edition . 1999.08; 10 (8): 795-804. ( DOI )

  14. *Satoshi Tanimoto, Daisuke Murotomi, Atsunori Hiratsuka, Hironobu Miyachi, Satoshi Sasaki, Kazuyoshi Yano, Kazunori Ikebukuro, Kohji Mitsubayashi, Isao Karube: Development of A Flexible Biosensor using A Film-type Oxygen Electrode. Chemical Sensors. 1999.08; 15 (B): 37-39.

  15. *Yuki Hashimoto, Yoshihiro Nakayama, Kohji Mitsubayashi: Development of A Biosensor for Trimethylamine. Chemical Sensors. 1999.08; 15 (B): 49-51.

  16. Y Tamada、T Furuzono、T Taguchi、A Kishida、M Akashi: Ca-adsorption and apatite deposition on silk fabrics modified with phosphate polymer chains. Journal of biomaterials science. Polymer edition. 1999.07; 10 (7): 787-793. ( DOI )

  17. M-Q.Chen、T.Serizawa、A.Kishida、M.Akashi: Graft copolymers having hydrophobic backbone and hydrophilic branches. XXIII. Particle size control of poly(ethylene glycol)‐coated polystyrene nanoparticles prepared by macromonomer method Journal of Polymer Science Part A:Polymer Chemistry. 1999.07; 37 (13): 2155-2166. ( DOI )

  18. Hagiyama H, Adachi T, Yoshida T, Nomura T, Miyasaka N, Honjo T, Tsubata T: Signaling through the antigen receptor of B lymphocytes activates a p53-independent pathway of c-Myc-induced apoptosis ONCOGENE. 1999.07; 18 (28): 4091-4098.

  19. Hagiyama H, Adachi T, Yoshida T, Nomura T, Miyasaka N, Honjo T, Tsubata T: Signaling through the antigen receptor of B lymphocytes activates a p53-independent pathway of c-Myc-induced apoptosis. Oncogene. 1999.07; 18 (28): 4091-4098. ( PubMed , DOI )

  20. F.Seto、Y.Muraoka、T.Akagi、A.Kishida、M.Akashi: Surface Grafting of Poly(vinylamine) onto Poly(ethylene) Film by Corona Discharge Induced Grafting. Journal of Applied Polymer Science . 1999.06; 72 (12): 1583-1587. ( DOI )

  21. Ishitani T, Ninomiya-Tsuji J, Nagai S, Nishita M, Meneghini M, Barker N, Waterman M, Bowerman B, Clevers H, Shibuya H, Matsumoto K: The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF. Nature. 1999.06; 399 (6738): 798-802. ( PubMed , DOI )

  22. F.Seto、Y.Muraoka、N.Sakamoto、A.Kishida、M.Akashi: Surface modification of synthetic fiber nonwoven fabrics with poly(acrylic acid) chains prepared by corona discharge induced grafting Angewandte Makromolekulare Chemie . 1999.05; 266 (1): 56-62. ( DOI )

  23. S.Sakoda、H.Shin、K.Yamaji、I.Takasaki、T.Furuzono、A.Kishida、M.Akashi、T.Kubo、E.Nagaoka、I.Maruyama、I.Kitajima: Mechanical stretching of human osteoblast-like cells stimulates bone morphogenic proteins and macrophage colony-stimulating factor productions. Pathophysiology. 1999.04; 6 (1): 63-69. ( DOI )

  24. Miyama K, Yamada G, Yamamoto TS, Takagi C, Miyado K, Sakai M, Ueno N, Shibuya H: A BMP-inducible gene, dlx5, regulates osteoblast differentiation and mesoderm induction. Dev Biol. 1999.04; 208 (1): 123-133. ( PubMed , DOI )

  25. Masuyama N, Hanafusa H, Kusakabe M, Shibuya H, Nishida E: Identification of two Smad4 proteins in Xenopus. Their common and distinct properties. J Biol Chem. 1999.04; 274 (17): 12163-12170. ( PubMed )

  26. Y Takeuchi, K Nishimura, N Aoki, T Adachi, C Sato, K Kitajima, T Matsuda: A 42-kDa glycoprotein from chicken egg-envelope, an avian homolog of the ZPC family glycoproteins in mammalian zona pellucida - Its first identification, cDNA cloning and granulosa cell-specific expression EUROPEAN JOURNAL OF BIOCHEMISTRY. 1999.03; 260 (3): 736-742. ( PubMed , DOI )

  27. T.Serizawa、H.Goto、A.Kishida、T.Endo、M.Akashi: Improved Alternate Deposition of Biodegradable Naturally Ocurring Polymers onto a Quartz Crystal Microbalance Journal of Polymer Science Part A: Polymer Chemistry. 1999.03; 37 (6): 801-804. ( DOI )

  28. Hamada F, Tomoyasu Y, Takatsu Y, Nakamura M, Nagai S, Suzuki A, Fujita F, Shibuya H, Toyoshima K, Ueno N, Akiyama T: Negative regulation of Wingless signaling by D-axin, a Drosophila homolog of axin. Science. 1999.03; 283 (5408): 1739-1742. ( PubMed )

  29. Xu Y, Tamamura H, Arakaki R, Nakashima H, Zhang X, Fujii N, Uchiyama T, Hattori T: Marked increase in anti-HIV activity, as well as inhibitory activity against HIV entry mediated by CXCR4, linked to enhancement of the binding ability of tachyplesin analogs to CXCR4. AIDS Res Hum Retroviruses. 1999.03; 15 (5): 419-427. ( PubMed , DOI )

  30. S.Kato、Y.Ueno、A.Kishida、T.Miyazaki、T.Matsumoto、Y.Murata、M.Akashi: Surface characterization of poly(styrene‐co‐ fluoroalkylfumarate): XPS and contact angle measurement study Journal of Applied Polymer Science. 1999.02; 71 (7): 1049-1054. ( DOI )

  31. Arakaki R, Tamamura H, Premanathan M, Kanbara K, Ramanan S, Mochizuki K, Baba M, Fujii N, Nakashima H: T134, a small-molecule CXCR4 inhibitor, has no cross-drug resistance with AMD3100, a CXCR4 antagonist with a different structure. J Virol. 1999.02; 73 (2): 1719-1723. ( PubMed )

  32. Yamaguchi K, Nagai S, Ninomiya-Tsuji J, Nishita M, Tamai K, Irie K, Ueno N, Nishida E, Shibuya H, Matsumoto K: XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway. EMBO J. 1999.01; 18 (1): 179-187. ( PubMed , DOI )

  33. Yamaguchi T, Ito S, Iwase Y, Watanabe K, Harano K.: Products from a novel reaction of dihydropyrazines with vichinaldiamines HETEROCYCLES. 1999; 51 (10): 2305-2309.

  34. Yamaguchi T, Eto M, Harano K, Kashige N, Watanabe K, Ito S.: New compounds derived from dihydropyrazines having DNA strand-breakage activity TETRAHEDRON. 1999; 55 (3): 675-686.

  35. Kumagai H, Sato N, Yamada M, Mahony D, Seghezzi W, Lees E, Arai K, Masai H: A novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells Mol Cell Biol. 1999; 19 (7): 5083-5095. ( PubMed )

  36. Masai H, Sato N, Takeda T, Arai K: CDC7 kinase complex as a molecular switch for DNA replication Front Biosci. 1999; 4 D834-40. ( PubMed )

  37. T.Taguchi、M.Shiraogawa、A.Kishida、M.Akashi: A study on hydroxyapatite formation on/in the hydroxyl groups-bearing nonionic hydrogels Journal of Biomaterials Science, Polymer Edition. 1999; 10 (1): 19-32. ( DOI )

  38. T.Taguchi、A.Kishida、M.Akashi: Apatite formation on/in hydrogel matrices using an alternate soaking process: II. Effect of swelling ratios of poly(vinyl alcohol) hydrogel matrices on apatite formation Journal of Biomaterials Science, Polymer Edition. 1999; 10 (3): 331-339. ( DOI )

  39. Hirokazu Tamamura, Masaki Yamashita, Yutaka Nakajima, Kyoko Sakano, Akira Otaka, Hiroaki Ohno, Toshiro Ibuka & Nobutaka Fujii: Regiospecific Ring-Opening Reactions of β-Aziridinyl α,β-Enoates with Acids: Application to the Stereoselective Synthesis of a Couple of Diastereoisomeric (E)-Alkene Dipeptide Isosteres from a Single β-Aziridinyl α,β-Enoate and to the Convenient Preparation of Amino Alcohols Bearing α,β-Unsaturated Ester Groups. J. Chem. Soc., Perkin Trans.. 1999; 1 2983-2996.

  40. Yasuda K: Measurement of microscopic spatial distribution of acoustic radiation force using microspheres and electrostatic force Jpn J Appl Phys. 1999; 38 3316-3319.

  1. Tamamura H, Xu Y, Hattori T, Zhang X, Arakaki R, Kanbara K, Omagari A, Otaka A, Ibuka T, Yamamoto N, Nakashima H, Fujii N: A low-molecular-weight inhibitor against the chemokine receptor CXCR4: a strong anti-HIV peptide T140. Biochem Biophys Res Commun. 1998.12; 253 (3): 877-882. ( PubMed , DOI )

  2. Miyahara Y: Intelligent and Micro Ion Sensors IEEJ Transactions on Sensors and Micromachines. 1998.12; 118 (12): 548-551.

  3. T.Taguchi、A.Kishida、N.Sakamoto、M.Akashi: Preparation of a novel functional hydrogel consisting of sulfated glucoside‐bearing polymer: Activation of basic fibroblast growth factor Journal of Biomedical Materials Research Part A. 1998.09; 41 (3): 386-391. ( DOI )

  4. CY Wu, T Adachi, T Hatano, H Washida, A Suzuki, F Takaiwa: Promoters of rice seed storage protein genes direct endosperm-specific gene expression in transgenic rice PLANT AND CELL PHYSIOLOGY. 1998.08; 39 (8): 885-889.

  5. N.Sakamoto、K.Suzuki、A.Kishida、M.Akashi: Preparation and swelling properties of glycoside‐bearing hydrogels by gamma‐ray radiation to glycoside‐bearing polymer aqueous solutions Journal of Applied Polymer Science. 1998.08; 70 (5): 965-972. ( DOI )

  6. A.Kishida、K.Murakami、H.Goto、H.Kubota、T.Endo、M.Akashi: Polymer Drugs and Polymeric Drugs - X. Slow Release of 5-Fluorouracil from Biodegradable Poly(γ-glutamic acid)and Its Benzyl Ester Matrices Journal of Bioactive and Compatible Polymers. 1998.08; 13 (4): 270-278. ( DOI )

  7. Wu CY, Adachi T, Hatano T, Washida H, Suzuki A, Takaiwa F: Promoters of rice seed storage protein genes direct endosperm-specific gene expression in transgenic rice PLANT AND CELL PHYSIOLOGY. 1998.08; 39 (8): 885-889.

  8. Hattori T, Komoda H, Pahwa S, Tateyama M, Zhang X, Xu Y, Oguma S, Tamamura H, Fujii N, Fukutake K, Uchiyama T: Decline of anti-DP107 antibody associated with clinical progression. AIDS. 1998.08; 12 (12): 1557-1559. ( PubMed )

  9. A.Kishida、H.Goto、K.Murakami、K.Kakinoki、T.Endo、M.Akashi: Polymer Drugs and Polymeric Drugs IX. Synthesis and 5-Fluorouracil Release Profiles of Biodegradable Polymeric Prodrugs γ-Poly(α-Hydroxymethyl-5-Fluorouracil-Glutamate) Journal of Bioactive and Compatible Polymers. 1998.07; 13 (3): 222-233. ( DOI )

  10. Tamamura H, Imai M, Ishihara T, Masuda M, Funakoshi H, Oyake H, Murakami T, Arakaki R, Nakashima H, Otaka A, Ibuka T, Waki M, Matsumoto A, Yamamoto N, Fujii N: Pharmacophore identification of a chemokine receptor (CXCR4) antagonist, T22 ([Tyr(5,12),Lys7]-polyphemusin II), which specifically blocks T cell-line-tropic HIV-1 infection. Bioorg Med Chem. 1998.07; 6 (7): 1033-1041. ( PubMed )

  11. F.Seto、K.Fukuyama、Y.Muraoka、A.Kishida、M.Akashi: Thermosensitive surface properties of polyethylene film with poly(N‐isopropylacrylamide) chains prepared by corona discharge induced grafting Journal of Applied Polymer Science. 1998.06; 68 (11): 1773-1779. ( DOI )

  12. Yamazaki T, Otomo T, Oda N, Kyogoku Y, Uegaki K, Ito N, Ishino Y, Nakamura H: Segmental isotope labeling for protein NMR using peptide splicing JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 1998.06; 120 (22): 5591-5592. ( DOI )

  13. Hotta H, Aoki N, Matsuda T, Adachi T: Molecular analysis of a novel protein kinase in maturing rice seed GENE. 1998.06; 213 (1-2): 47-54.

  14. Oguchi M, Higashi K, Taniguchi M, Nishikawa T, Tamamura H, Okimura T, Yamamoto I: Single photon emission CT images in a case of intraventricular neurocytoma. Ann Nucl Med. 1998.06; 12 (3): 161-164. ( PubMed )

  15. Hotta H, Aoki N, Matsuda T, Adachi T: Molecular analysis of a novel protein kinase in maturing rice seed. Gene. 1998.06; 213 (1-2): 47-54. ( PubMed )

  16. Adachi T, Flaswinkel H, Yakura H, Reth M, Tsubata T: Cutting edge: The B cell surface protein CD72 recruits the tyrosine phosphatase SHP-1 upon tyrosine phosphorylation JOURNAL OF IMMUNOLOGY. 1998.05; 160 (10): 4662-4665.

  17. Adachi T, Flaswinkel H, Yakura H, Reth M, Tsubata T: The B cell surface protein CD72 recruits the tyrosine phosphatase SHP-1 upon tyrosine phosphorylation. J Immunol. 1998.05; 160 (10): 4662-4665. ( PubMed )

  18. S.Kato、T.Akagi、K.Sugimura、A.Kishida、M.Akashi: Evaluation of biological responses to polymeric biomaterials by RT-PCR analysis III: Study of HSP 70, 90 and 47 mRNA expression Biomaterials. 1998.04; 19 (7-9): 821-827. ( DOI )

  19. Tamamura H, Waki M, Imai M, Otaka A, Ibuka T, Waki K, Miyamoto K, Matsumoto A, Murakami T, Nakashima H, Yamamoto N, Fujii N: Downsizing of an HIV-cell fusion inhibitor, T22 ([Tyr5,12, Lys7]-polyphemusin II), with the maintenance of anti-HIV activity and solution structure. Bioorg Med Chem. 1998.04; 6 (4): 473-479. ( PubMed )

  20. Kurozumi K, Nishita M, Yamaguchi K, Fujita T, Ueno N, Shibuya H: BRAM1, a BMP receptor-associated molecule involved in BMP signalling. Genes Cells. 1998.04; 3 (4): 257-264. ( PubMed )

  21. Y.Baba、T.Sawa、A.Kishida、M.Akashi: Base‐specific separation of oligodeoxynucleotides by capillary affinity gel electrophoresis Electrophoresis. 1998.03; 19 (3): 433-436. ( DOI )

  22. M Oubihi, K Kitajima, K Kobayashi, T Adachi, N Aoki, T Matsuda: Development of an enzyme-linked immunosorbent assay-based method for measuring galactosyltransferase activity using a synthetic glycopolymer acceptor substrate ANALYTICAL BIOCHEMISTRY. 1998.03; 257 (2): 169-175. ( PubMed , DOI )

  23. Tamamura H, Arakaki R, Funakoshi H, Imai M, Otaka A, Ibuka T, Nakashima H, Murakami T, Waki M, Matsumoto A, Yamamoto N, Fujii N: Effective lowly cytotoxic analogs of an HIV-cell fusion inhibitor, T22 ([Tyr5,12, Lys7]-polyphemusin II). Bioorg Med Chem. 1998.02; 6 (2): 231-238. ( PubMed )

  24. Shibuya H, Iwata H, Masuyama N, Gotoh Y, Yamaguchi K, Irie K, Matsumoto K, Nishida E, Ueno N: Role of TAK1 and TAB1 in BMP signaling in early Xenopus development. EMBO J. 1998.02; 17 (4): 1019-1028. ( PubMed , DOI )

  25. A.Kishida、S.Nakano、Y.Kikunaga、M.Akashi: Synthesis and functionalities of poly(N‐vinylalkylamide). VII. A novel aqueous two‐phase systems based on poly(N‐vinylacetamide) and dextran Journal of Applied Polymer Science . 1998.01; 67 (2): 255-258. ( DOI )

  26. Fujii T, Miyahara Y: Infrared ATR spectroscopy of substrates in aqueous solution using cryoenrichment and its application in enzyme-activity assays Appl Spectrosc. 1998.01; 52 (1): 128-133.

  27. M Oubihi, K Kitajima, K Kobayashi, T Adachi, N Aoki, T Matsuda: Development of an ELISA based assay for measuring glycosyltransferase activity using synthetic glycopolymers ANIMAL CELL TECHNOLOGY: BASIC & APPLIED ASPECTS, VOL 9. 1998; 171-176.

  28. T Adachi, H Flaswinkel, H Yakura, M Reth, T Tsubata: The B cell surface protein CD72 recruits the tyrosine phosphatase SHP-1 upon tyrosine phosphorylation 10TH INTERNATIONAL CONGRESS ON IMMUNOLOGY, VOLS 1 AND 2. 1998; 341-344.

  29. T.Taguchi、A.Kishida、M.Akashi: Hydroxyapatite Formation on/in Poly(vinyl alcohol) Hydrogel Matrices Using a Novel Alternate Soaking Process Chemistry Letters. 1998; 27 (8): 711-712. ( DOI )

  30. 玉村　啓和・藤井　信孝: Coreceptorを標的とした抗エイズ薬剤の開発状況 日本ME学会雑誌BioMedical Engineering. 1998; 12 (10): 44-51.

  31. Fujisawa S, Kadoma Y, Ito S: DSC and NMR spectroscopic studies of the interaction between Camphorated phenol and phospholipid liposomes DENT MATER J. 1998; 17 (4): 314-320.

  32. Nakase M, Usui Y, Alvarez-Nakase AM, Adachi T, Urisu A, Nakamura R, Aoki N, Kitajima K, Matsuda T: Cereal allergens: rice-seed allergens with structural similarity to wheat and barley allergens. Allergy. 1998; 53 (46 Suppl): 55-57. ( PubMed )

  33. Chuan-Yin Wu, Takahiro Adachi, Tetsuya Hatano, Haruhiko Washida, Akihiro Suzuki, Fumio Takaiwa: Promoters of rice seed storage protein genes direct endosperm-specific gene expression in transgenic rice Plant and Cell Physiology. 1998; 39 (8): 885-889. ( DOI )

  34. Kim JM, Sato N, Yamada M, Arai K, Masai H: Growth regulation of the expression of mouse cDNA and gene encoding a serine/threonine kinase related to Saccharomyces cerevisiae CDC7 essential for G1/S transition. Structure, chromosomal localization, and expression of mouse gene for s. cerevisiae Cdc7-related kinase J Biol Chem. 1998; 273 (36): 23248-23257. ( PubMed )

  35. Hirokazu Tamamura, Tsunehito Ishihara, Hiromi Oyake, Makoto Imai, Akira Otaka, Toshiro Ibuka, Rieko Arakaki, Hideki Nakashima, Tsutomu Murakami, Michinori Waki, Akiyoshi Matsumoto, Naoki Yamamoto & Nobutaka Fujii: Convenient One-pot Synthesis of Cystine-Containing Peptides Using the Trimethylsilyl Chloride-Dimethylsulfoxide/Trifluoroacetic Acid System and its Application to the Synthesis of Bifunctional Anti-HIV Compounds. J. Chem. Soc., Perkin Trans.. 1998; 1 (3): 495-500.

  36. Hiroaki Ohno, Kiyonori Ishii, Asami Honda, Hirokazu Tamamura, Nobutaka Fujii, Yoshiji Takemoto & Toshiro Ibuka: A 2,3-cis-Selective Synthesis of Aziridines Bearing a Vinyl Group from Allyl Methyl Carbonates and Allyl Mesylates. J. Chem. Soc., Perkin Trans.. 1998; 1 (22): 3703-3716.

  37. Uenishi H, Iwanami N, Yamagishi H, Nakatani T, Kawasaki T, Tamamura H, Fujii N, Kuribayashi K: Induction of cross-reactivity in an endogenous viral peptide non-reactive to FBL-3 tumor-specific helper T-cell clones. Microbiol Immunol. 1998; 42 (7): 479-484. ( PubMed )

  38. Harada Y, Yasuda K, Nomura S, Kajimura N, Sasaki YC: Vectorially oriented fixation of membrane-embedded bacteriorhodopsin onto an inert base Langmiur. 1998; 14 1829-1835.

  1. S.Sakuma、N.Suzuki、H.Kikuchi、K.Hiwatari、K.Arikawa、A.Kishida、M.Akashi: Absorption enhancement of orally administered salmon calcitonin by polystyrene nanoparticles having poly(N-isopropylacrylamide) branches on their surfaces International Journal of Pharmaceutics . 1997.12; 158 (1): 69-78. ( DOI )

  2. S.Sakuma、Y.Ishida、R.Sudo、N.Suzuki、H.Kikuchi、K.Hiwatari、A.Kishida、M.Akashi、M.Hayashi: Stabilization of salmon calcitonin by polystyrene nanoparticles having surface hydrophilic polymeric chains, against enzymatic degradation International Journal of Pharmaceutics. 1997.12; 159 (2): 181-189. ( DOI )

  3. K.Suwa、K.Morisita、A.Kishida、M.Akashi: Synthesis and functionalities of poly(N‐vinylalkylamide). V. Control of a lower critical solution temperature of poly(N‐vinylalkylamide) Journal of Polymer Science Part A: Polymer Chemistry . 1997.11; 35 (15): 3087-3094. ( DOI )

  4. K.Suwa、Y.Wada、A.Kishida、M.Akashi: Synthesis and functionalities of poly(N-vinylalkylamide). VI. A novel thermosensitive hydrogel crosslinked poly(N-vinylisobutyramide) Journal of Polymer Science Part A: Polymer Chemistry . 1997.11; 35 (16): 3377-3384. ( DOI )

  5. Fujii T, Miyahara Y, Watanabe Y: Highly sensitive biochemical analysis using low-temperature infrared spectroscopy measurements Appl Spectrosc. 1997.11; 51 (11): 1682-1686.

  6. Murakami T, Nakajima T, Koyanagi Y, Tachibana K, Fujii N, Tamamura H, Yoshida N, Waki M, Matsumoto A, Yoshie O, Kishimoto T, Yamamoto N, Nagasawa T: A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection. J Exp Med. 1997.10; 186 (8): 1389-1393. ( PubMed )

  7. S.Kato、T.Akagi、A.Kishida、K.Sugimura、M.Akashi: Evaluation of biological responses to polymeric biomaterials by RT-PCR analysis II: Study of HSP 70 mRNA expression Journal of Biomaterials Science, Polymer Edition. 1997.09; 8 (10): 809-814. ( DOI )

  8. Akiyama S, Katagiri T, Namiki M, Yamaji N, Yamamoto N, Miyama K, Shibuya H, Ueno N, Wozney JM, Suda T: Constitutively active BMP type I receptors transduce BMP-2 signals without the ligand in C2C12 myoblasts. Exp Cell Res. 1997.09; 235 (2): 362-369. ( PubMed , DOI )

  9. K.Senshu、T.Furuzono、N.Koshizaki、S.Yamashita、T.Matumoto、A.Kishida 、M.Akashi: Novel Functional Polymers:  Poly(dimethylsiloxane)−Polyamide Multiblock Copolymer. 8.1 Surface Studies of Aramid−Silicone Resin by Means of XPS, Static SIMS, and TEM Macromolecules. 1997.07; 30 (15): 4421-4428. ( DOI )

  10. N.Sakamoto、T.Shioya、A.Kishida、M.Akashi: Preparation and anticoagulant surface properties of glucoside- or sulfated glucoside-bearing polymer grafted poly(ethylene) films. Macromolecular Symposia. 1997.07; 120 (1): 159-167.

  11. Hidehiko Tsuji, Kohji Mitsubayashi: An amperometric glucose sensor with modified Lagmuir-Blodgett films. ELECTROANALYSIS. 1997.07; 9 (1): 1-4.

  12. K.Suwa、Y.Wada、Y.Kikunaga、K.Morishita、A.Kishida、M.Akashi : Synthesis and Functionalities of Poly(N-Vinylalkylamide). IV. Synthesis and Free Radical Polymerization of N-Vinylisobutyramide and Thermosensitive Properties of the Polymer. Journal of Polymer Science Part A: Polymer Chemistry. 1997.07; 35 (9): 1763-1768. ( DOI )

  13. Ibuka T, Mimura N, Ohno H, Nakai K, Akaji M, Habashita H, Tamamura H, Miwa Y, Taga T, Fujii N, Yamamoto Y: Palladium(0)-Catalyzed Isomerization Reactions of Aziridines Bearing an alpha,beta-Unsaturated Ester Group: A Thermodynamic Preference for Chiral Alkyl (2E)-4,5-cis-4,5-Epimino-N-(alkyl- or arylsulfonyl) 2-Enoates over the Other Three Stereoisomers. J Org Chem. 1997.05; 62 (9): 2982-2991. ( PubMed )

  14. Fujii T, Miyahara Y: Simultaneous Analyses of Biochemical Components in Blood Using Infrared Spectroscopy Combined with Partial Least Squares IEEJ Transactions on Sensors and Micromachines. 1997.05; 117 (6): 332-337.

  15. T.Matsumoto、T.Uchida、A.Kishida、T.Furuzono、I.Maruyama、M.Akashi: Novel functional polymers: Poly(dimethylsiloxane)‐polyamide multiblock copolymer. VII. Oxygen permeability of aramid‐silicone membranes in a gas‐membrane‐liquid system Journal of Applied Polymer Science . 1997.05; 64 (6): 1153-1159. ( DOI )

  16. S.Sakuma、N.Suzuki、H.Kikuchi、K.Hiwawtari、K.Arikawa、A.Kishida、M.Akashi: Oral peptide delivery using nanoparticles composed of novel graft polymers having hydrophobic backbone and hydrophilic branches International Journal of Pharmaceutics. 1997.04; 149 (1): 93-106. ( DOI )

  17. Aoki N, Ishii T, Ohira S, Yamaguchi Y, Negi M, Adachi T, Nakamura R, Matsuda T: Stage specific expression of milk fat globule membrane glycoproteins in mouse mammary gland: comparison of MFG-E8, butyrophilin, and CD36 with a major milk protein, beta-casein. Biochim Biophys Acta. 1997.03; 1334 (2-3): 182-190. ( PubMed )

  18. Shirakabe K, Yamaguchi K, Shibuya H, Irie K, Matsuda S, Moriguchi T, Gotoh Y, Matsumoto K, Nishida E: TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase. J Biol Chem. 1997.03; 272 (13): 8141-8144. ( PubMed )

  19. T.Furuzono、K.Senshu、A.Kishida、T.Matsumoto、M.Akashi: Novel Functional Polymers: Poly(dimethylsiloxane)-Polyamide Multiblock Copolymer VI. A Transmission Electron Microscopic Study on Microphase-Separated Structure in Aramid-Silicone Resin Polymer Journal. 1997.02; 29 (2): 201-203.

  20. Nakase M, Aoki N, Matsuda T, Adachi T: Characterization of a novel rice bZIP protein which binds to the alpha-globulin promoter. Plant Mol Biol. 1997.02; 33 (3): 513-522. ( PubMed )

  21. Ito S, Fujisawa S: Complete C-13 NMR assignment of the dental adhesive monomer 4-methacryloyloxyethyl trimellitate anhydride and its hydrate MAGN RESON CHEM. 1997; 35 (3): 213-214.

  22. Sato N, Arai K, Masai H: Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7 EMBO J. 1997; 16 (14): 4340-4351. ( PubMed , DOI )

  23. Hiroshi Aoyama, Norio Mimura, Hiroaki Ohno, Kiyonori Ishii, Ayako Toda, Hirokazu Tamamura, Akira Otaka, Nobutaka Fujii & Toshiro Ibuka: Regio- and Stereoselectivity in Reactions of 2,3-cis- and trans-3-Alkyl-2-vinylaziridines with Organocopper Reagents: Importance of 2,3-cis-Stereochemistry in Controlling Selectivity. Tetrahedron Lett.. 1997; 38 (42): 7383-7386.

  24. Hiroaki Ohno, Norio Mimura, Akira Otaka, Hirokazu Tamamura, Nobutaka Fujii, Toshiro Ibuka, Isao Shimizu, Akiharu Satake & Yoshinori Yamamoto: Palladium-Catalyzed Reductive Ring Opening with Formic Acid of Aziridines Bearing an α, β-Unsaturated Ester Group. Tetrahedron. 1997; 53 (38): 12933-12946.

  25. Sasaki YC, Yasuda K, Suzuki Y, Ishibashi T, Satoh I, Fujiki Y, Ishiwata S: Two-dimensional arrangement of a functional protein by cysteine-gold interaction: enzyme activity and characterization of a protein monolayer on a gold substrate Biophys J. 1997; 72 1842-1848.

  26. Yasuda K: Blood concentration by superposition of higher harmonics of ultrasound Jpn J Appl Phys. 1997; 36 3130-3135.

  27. Ishiwata S, Miki M, Shin I, Funatsu T, Yasuda K, dos Remedios CG: Interhead distances in myosin attached to F-actin estimated by fluorescence energy transfer spectroscopy Biophys J. 1997; 73 895-904.

  28. Yasuda K, Haupt SS, Umemura S, Yagi T, Nishida M, Shibata Y: Using acoustic radiation force as a concentration method for erythrocytes J Acoust Soc Am. 1997; 102 642-645.

  29. Yasuda K, Kamakura T: Acoustic radiation force on micrometer-size particles Appl Phys Lett . 1997; 71 1771-1773.

  30. Toshiro Ibuka, Norio Mimura, Hiroshi Aoyama, Masako Akaji, Hiroaki Ohno, Yoshihisa Miwa, Tooru Taga, Kazuo Nakai, Hirokazu Tamamura, Nobutaka Fujii & Yoshinori Yamamoto: A Thermodynamic Preference of Chiral N-Methanesulfonyl and N-Arenesulfonyl 2,3-cis-3-Alkyl-2-vinylaziridines over Their 2,3-trans-Isomers: Useful Palladium(0)-Catalyzed Equilibration Reactions for the Synthesis of (E)-Alkene Dipeptide Isosters. J. Org. Chem.. 1997; 62 (4): 999-1015.

  31. N.Sakamoto、A.Kishida、I.Maruyama、M.Akashi: The mechanism of anticoagulant activity of a novel heparinoid sulfated glucoside-bearing polymer Journal of Biomaterials Science, Polymer Edition. 1997; 8 (7): 545-553. ( DOI )

  32. Hiromu Habashita, Takeshi Kawasaki, Masako Akaji, Hirokazu Tamamura, Tetsutaro Kimachi, Nobutaka Fujii & Toshiro Ibuka: One-Pot Transformation of p-Toluenesulfonates of 2,3-Epoxy Alcohols into Allylic Alcohols. Tetrahedron Lett.. 1997; 38 (48): 8307-8310.

  1. Tamamura H, Otaka A, Murakami T, Ibuka T, Sakano K, Waki M, Matsumoto A, Yamamoto N, Fujii N: An anti-HIV peptide, T22, forms a highly active complex with Zn(II). Biochem Biophys Res Commun. 1996.12; 229 (2): 648-652. ( PubMed , DOI )

  2. Adachi T, Ahn JY, Yamamoto K, Aoki N, Nakamura R, Matsuda T: Characterization of the bovine kappa-casein gene promoter. Biosci Biotechnol Biochem. 1996.12; 60 (12): 1937-1940. ( PubMed )

  3. Lee Geunsu, Oka Masakazu, Takemura Hiroyuki, Miyahara Yuji, Shimizu Nobujiro, Inazu Takahiko: Efficient Synthesis of 2,11,20-Triaza[3.3.3](2,6)pyridinophane. J Org Chem. 1996.11; 61 (23): 8304-8306. ( PubMed )

  4. Tamamura H, Ishihara T, Otaka A, Murakami T, Ibuka T, Waki M, Matsumoto A, Yamamoto N, Fujii N: Analysis of the interaction of an anti-HIV peptide, T22 ([Tyr5, 12, Lys7]-polyphemusin II), with gp120 and CD4 by surface plasmon resonance. Biochim Biophys Acta. 1996.11; 1298 (1): 37-44. ( PubMed )

  5. J.S.Hong、T.Nakahara、H.Maeda、Y.Kikunaga、A.Kishida、M.Akashi: Cloud points and phase separation of aqueous poly(N-vinylacetamide) solutions in the presence of salts. Colloid and Polymer Science. 1996.11; 274 (11): 1013-1019. ( DOI )

  6. Nakase M, Yamada T, Kira T, Yamaguchi J, Aoki N, Nakamura R, Matsuda T, Adachi T: The same nuclear proteins bind to the 5'-flanking regions of genes for the rice seed storage protein: 16 kDa albumin, 13 kDa prolamin and type II glutelin. Plant Mol Biol. 1996.11; 32 (4): 621-630. ( PubMed )

  7. Miyahara Y, Yamashita K, Ozawa S, Watanabe Y: Shift and drift of electromotive forces of solid-state electrodes with ion-selective liquid membranes Anal Chim Acta. 1996.09; 331 (1-2): 85-95.

  8. M.Q.Chen、A.Kishida、M.Akashi: Graft copolymers having hydrophobic backbone and hydrophilic branches. XI. Preparation and thermosensitive properties of polystyrene microspheres having poly (N‐isopropylacrylamide) branches on their surfaces Journal of Polymer Science Part A: Polymer Chemistry . 1996.08; 34 (11): 2213-2220. ( DOI )

  9. T.Furuzono、A.Kishida、M.Yanagi、T.Matsumoto、T.Kanda、T.Nakamura、T.Aiko、I.Maruyama、M.Akashi: Novel functional polymers: Poly(dimethylsiloxane)-polyamide multiblock copolymer V*. The interaction between biomolecules and the surface of aramid-silicone resins Journal of Biomaterials Science, Polymer Edition. 1996.08; 7 (10): 871-880. ( DOI )

  10. Tada Y, Nakase M, Adachi T, Nakamura R, Shimada H, Takahashi M, Fujimura T, Matsuda T: Reduction of 14-16 kDa allergenic proteins in transgenic rice plants by antisense gene. FEBS Lett. 1996.08; 391 (3): 341-345. ( PubMed )

  11. M.Akashi、N.Sakamoto、K.Suzuki、A.Kishida: Synthesis and Anticoagulant Activity of Sulfated Glucoside-Bearing Polymer. Bioconjugate Chemistry. 1996.07; 7 (4): 393-395. ( DOI )

  12. A.Kishida、S.Kato、K.Ohmura、K.Sugimura、M.Akashi: Evaluation of biological responses to polymeric biomaterials by RT-PCR analysis: I. Study of IL-1β mRNA expression Biomaterials. 1996.07; 17 (13): 1301-1305. ( DOI )

  13. Miyahara Y: I. Integrated Biochemical Sensors IEEJ Transactions on Electronics, Information and Systems. 1996.07; 116 (8): 880-882.

  14. Moriguchi T, Kuroyanagi N, Yamaguchi K, Gotoh Y, Irie K, Kano T, Shirakabe K, Muro Y, Shibuya H, Matsumoto K, Nishida E, Hagiwara M: A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3. J Biol Chem. 1996.06; 271 (23): 13675-13679. ( PubMed )

  15. Nakase M, Alvarez AM, Adachi T, Aoki N, Nakamura R, Matsuda T: Immunochemical and biochemical identification of the rice seed protein encoded by cDNA clone A3-12. Biosci Biotechnol Biochem. 1996.06; 60 (6): 1031-1032. ( PubMed )

  16. Shibuya H, Yamaguchi K, Shirakabe K, Tonegawa A, Gotoh Y, Ueno N, Irie K, Nishida E, Matsumoto K: TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. Science. 1996.05; 272 (5265): 1179-1182. ( PubMed )

  17. Nakase M, Hotta H, Adachi T, Aoki N, Nakamura R, Masumura T, Tanaka K, Matsuda T: Cloning of the rice seed alpha-globulin-encoding gene: sequence similarity of the 5'-flanking region to those of the genes encoding wheat high-molecular-weight glutenin and barley D hordein. Gene. 1996.05; 170 (2): 223-226. ( PubMed )

  18. Adachi T, Schamel WW, Kim KM, Watanabe T, Becker B, Nielsen PJ, Reth M: The specificity of association of the IgD molecule with the accessory proteins BAP31/BAP29 lies in the IgD transmembrane sequence. EMBO J. 1996.04; 15 (7): 1534-1541. ( PubMed )

  19. T.Furuzono、K.Seki、A.Kishida、T.Ohshige、K.Waki、I.Maruyama、M.Akashi: Novel functional polymers: Poly(dimethylsiloxane)–polyamide multiblock copolymer. III. Synthesis and surface properties of disiloxane–aromatic polyamide multiblock copolymer Journal of Applied Polymer Science . 1996.02; 59 (7): 1059-1065. ( DOI )

  20. T.Matsumoto、Y.Koinuma、K.Waki、A.Kishida、T.Furuzono、I.Maruyama、M.Akashi: Novel functional polymers: Poly(dimethylsiloxane)–polyamide multiblock copolymer. IV. Gas permeability and thermomechanical properties of aramid–silicone resins Journal of Applied Polymer Science . 1996.02; 59 (7): 1067-1071. ( DOI )

  21. Tamamura H, Otaka A, Murakami T, Ishihara T, Ibuka T, Waki M, Matsumoto A, Yamamoto N, Fujii N: Interaction of an anti-HIV peptide, T22, with gp120 and CD4. Biochem Biophys Res Commun. 1996.02; 219 (2): 555-559. ( PubMed , DOI )

  22. M.Akashi、S.Nakano、A.Kishida: Synthesis of poly(N‐vinylisobutyramide) from poly(N‐vinylacetamide) and its thermosensitive property Journal of Polymer Science Part A: Polymer Chemistry . 1996.01; 34 (2): 301-303. ( DOI )

  23. Tsukasa Matsuda, Masahiro Nakase, Takahiro Adachi, Ryo Nakamura, Yuichi Tada, Hiroaki Shimada, Masayoshi Takahashi, Tasuhito Fujimura: Allergenic proteins in Rice : Strategies for reduction and evaluation G.Eisenbrand, H.Aulepp, A.D.Dayan, P.S.Elias, W.Grunow, J.Ring, J.Schlatter(eds.) Food Allergies and Intolerances, Section III. The Input of Molecular Biology: Transgenic Foods.. 1996; 161-169.

  24. Sekine H, Ito S, Nakahara Y, Suzuki S: Smoking abuse of Methanphetamine Mixed with Tabacco. Thermal properties of N-cyanomethylmethamphetamine and its degradation in plasma and aqueous media, Japanese Journal Toxycology and Enviromental Health. 1996; 42 (3): 223-235.

  25. Fujita H, Yasuda K, Niitsu S, Funatsu T, Ishiwata S: Structual and functional reconstitution of thin filaments in the contractile apparatus of cardiac muscle Biophys J. 1996; 71 2307-2318.

  26. Moriyama Y, Yasuda K, Ishiwata S, Asai H: Ca2+ -induced tension delvelopment in the stalks of glycerinated vorticella convallaria Cell Motil Cytoskeleton . 1996; 34 271 -278.

  27. Ishiwata S, Yasuda K, Shindo Y, Fujita H: Microscopic analysis of the elastic properties of connectin/titin and nebulin in myofibrils Adv. Biophys. . 1996; 33 135-142 -142.

  28. Yasuda K, Takeda K , Umemura S: Studies on particle separation by acoustic radiation force and electrostaticforce Jpn J Appl Phys. 1996; 35 3295 -3299.

  29. Yasuda K, Takeda K, Umemura S: Deoxyribonucleic acid concentration using acoustic radiation force J Acoust Soc Am. 1996; 99 1248-1250.

  30. Yasuda K, Shindo Y, Ishiwata S: Synchronous behavior of spontaneous oscillations of sarcomeres in skeletal myofibrils under isotonic conditions Biophys J. 1996; 70 1823-1829.

  31. Yasuda K, Umemura S, Takeda K: Particle separation using acoustic radiation force and electrostaticforce J Acoust Soc Am. 1996; 99 1965-1970.

  32. Toshiro Ibuka, Kazuo Nakai, Masako Akaji, Hirokazu Tamamura, Nobutaka Fujii & Yoshinori Yamamoto: An Aza-Payne Rearrangement-Epoxide Ring Opening Reaction of 2-Aziridinemethanols in a One-pot Manner: A Regio- and Stereoselective Synthetic Route to Diastereomerically Pure N-Protected 1,2-Amino Alcohols. Tetrahedron. 1996; 52 11739-11752.

  33. Hosoya T, Takashiro E, Yamamoto Y, Matsumoto T, Suzuki K.: Total Syntheses of BE-12406 A and Its C(8)-Vinyl Analog. Heterocycles. 1996; 42 (1): 397-414. ( DOI )

  34. Hosoya T, Ohashi Y, Matsumoto T, Suzuki K.: On the Stereochemistry of Aryl C-Glycosides: Unusual Behavior of Bis-TBDPS Protected Aryl C-Olivosides. Tetrahedron Lett. 1996; 37 (5): 663-666. ( DOI )

  35. Hirokazu Tamamura, Tsunehito Ishihara, Akira Otaka, Takaki Koide, Kengo Miyoshi, Toshiro Ibuka & Nobutaka Fujii: A Convenient One-pot Synthesis of Cystine-Containing Peptides from Protected Peptidyl Resins Using the Trimethylsilyl Chloride-Dimethylsulfoxide-Trifluoroacetic Acid System. J. Chem. Soc., Perkin Trans. (Perkin Commun.). 1996; 1 1911-1912.

  36. Toshiro Ibuka, Masako Akaji, Norio Mimura, Hiromu Habashita, Kazuo Nakai, Hirokazu Tamamura, Nobutaka Fujii & Yoshinori Yamamoto: A Thermodynamic Preference of Chiral cis-γ,δ-Epimino-(E)-α,β-Unsaturated Esters over Other Stereoisomers: Synthetically Useful Pd(0)-Catalyzed Equilibrated Reactions of Aziridines Bearing an α,β-Unsaturated Ester Groups. Tetrahedron Lett.,. 1996; 37 2849-2852.

  37. Norio Mimura, Toshiro Ibuka, Masako Akaji, Yoshihisa Miwa, Tooru Taga, Kazuo Nakai, Hirokazu Tamamura, Nobutaka Fujii & Yoshinori Yamamoto: An Unusual Thermodynamic Preference of Chiral N-Arylsulfonyl cis-3-Alkyl-2-vinylaziridines over Their trans-Isomers: Palladium(0)-Catalyzed Equilibration Reaction. J. Chem. Soc., Chem. Commun.. 1996; 351-352.

  38. Tsukasa Matsuda, Masahiro Nakase, Takahiro Adachi, Ryo Nakamura, Yuichi Tada, Hiroaki Shimada, Masayoshi Takahashi, Tasuhito Fujimura: Allergenic proteins in Rice : Strategies for reduction and evaluation G.Eisenbrand, H.Aulepp, A.D.Dayan, P.S.Elias, W.Grunow, J.Ring, J.Schlatter(eds.) Food Allergies and Intolerances, Section III. The Input of Molecular Biology: Transgenic Foods.. 1996; 161-169.

  39. Nobutaka Fujii, Hiromu Habashita, Masako Akaji, Kazuo Nakai, Toshiro Ibuka, Masahiro Fujiwara, Hirokazu Tamamura & Yoshinori Yamamoto: A Simple One-pot Transformation of p-Toluenesulfonates of 2,3-Epoxy Alcohols into Allylic Alcohols. J. Chem. Soc., Perkin Trans. (Perkin Commun.). 1996; 1 1996, 865-866.

  40. Michinori Waki, Koji Waki, Kenji Miyamoto, Akiyoshi Matsumoto, Hirokazu Tamamura, Nobutaka Fujii, Tsutomu Murakami, Hideki Nakashima & Naoki Yamamoto: Molecular Size of an Anti-HIV Peptide, T22, Can Be Reduced without Loss of the Activity. Chem. Lett.. 1996; 571-572.

  1. Yamaguchi K, Shirakabe K, Shibuya H, Irie K, Oishi I, Ueno N, Taniguchi T, Nishida E, Matsumoto K: Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction. Science. 1995.12; 270 (5244): 2008-2011. ( PubMed )

  2. Ishii T, Aoki N, Noda A, Adachi T, Nakamura R, Matsuda T: Carboxy-terminal cytoplasmic domain of mouse butyrophilin specifically associates with a 150-kDa protein of mammary epithelial cells and milk fat globule membrane. Biochim Biophys Acta. 1995.12; 1245 (3): 285-292. ( PubMed )

  3. Aoki N, Kishi M, Taniguchi Y, Adachi T, Nakamura R, Matsuda T: Molecular cloning of glycoprotein antigens MGP57/53 recognized by monoclonal antibodies raised against bovine milk fat globule membrane. Biochim Biophys Acta. 1995.12; 1245 (3): 385-391. ( PubMed )

  4. Kondo T, Uenishi H, Shimizu T, Hirama T, Iwashiro M, Kuribayashi K, Tamamura H, Fujii N, Fujisawa R, Miyazawa M, et al.: A single retroviral gag precursor signal peptide recognized by FBL-3 tumor-specific cytotoxic T lymphocytes. J Virol. 1995.11; 69 (11): 6735-6741. ( PubMed )

  5. Weeks BS, Nomizu M, Otaka A, Weston CA, Okusu A, Tamamura H, Yamamoto N, Fujii N: The synthetic [Tyr5,12,Lys7]-polyphemusin II peptide (T22) binds to the CD4 cell surface molecule. Biochem Biophys Res Commun. 1995.10; 215 (2): 626-631. ( PubMed , DOI )

  6. Alvarez AM, Adachi T, Nakase M, Aoki N, Nakamura R, Matsuda T: Classification of rice allergenic protein cDNAs belonging to the alpha-amylase/trypsin inhibitor gene family. Biochim Biophys Acta. 1995.09; 1251 (2): 201-204. ( PubMed )

  7. ITO N, KOMIYAMA NH, FERMI G: STRUCTURE OF DEOXYHEMOGLOBIN OF THE ANTARCTIC FISH PAGOTHENIA-BERNACCHII WITH AN ANALYSIS OF THE STRUCTURAL BASIS OF THE ROOT EFFECT BY COMPARISON OF THE LIGANDED AND UNLIGANDED HEMOGLOBIN STRUCTURES JOURNAL OF MOLECULAR BIOLOGY. 1995.07; 250 (5): 648-658. ( DOI )

  8. A.Kishida、Y.Akatsuka、M.Yanagi、T.Aikou、I.Maruyama、M.Akashi: In Vivo and Ex Vivo Evaluation of the Antithrombogenicity of Human Thrombomodulin Immobilized Biomaterials. ASAIO Journal. 1995.07; 41 (3): M369-M374. ( DOI )

  9. Alvarez AM, Fukuhara E, Nakase M, Adachi T, Aoki N, Nakamura R, Matsuda T: Four rice seed cDNA clones belonging to the alpha-amylase/trypsin inhibitor gene family encode potential rice allergens. Biosci Biotechnol Biochem. 1995.07; 59 (7): 1304-1308. ( PubMed )

  10. *Kohji Mitsubayashi, Katsunori Ogasawara, Kenji Yokoyama, Toshifumi Takeuchi, Tadahiko Tsuru and Isao Karube: Measurement of tear electrolyte concentration and turnover rate using a flexible conductimetric sensor. TECHNOLOGY AND HEALTH CARE. 1995.06; 3 117-121.

  11. NAGAI K, OUBRIDGE C, ITO N, AVIS J, EVANS P: THE RNP DOMAIN - A SEQUENCE-SPECIFIC RNA-BINDING DOMAIN INVOLVED IN PROCESSING AND TRANSPORT OF RNA TRENDS IN BIOCHEMICAL SCIENCES. 1995.06; 20 (6): 235-240. ( DOI )

  12. OUBRIDGE C, ITO N, TEO CH, FEARNLEY I, NAGAI K: CRYSTALLIZATION OF RNA-PROTEIN COMPLEXES .2. THE APPLICATION OF PROTEIN ENGINEERING FOR CRYSTALLIZATION OF THE U1A PROTEIN-RNA COMPLEX JOURNAL OF MOLECULAR BIOLOGY. 1995.06; 249 (2): 409-423. ( DOI )

  13. PRICE SR, ITO N, OUBRIDGE C, AVIS JM, NAGAI K: CRYSTALLIZATION OF RNA-PROTEIN COMPLEXES .1. METHODS FOR THE LARGE-SCALE PREPARATION OF RNA SUITABLE FOR CRYSTALLOGRAPHIC STUDIES JOURNAL OF MOLECULAR BIOLOGY. 1995.06; 249 (2): 398-408. ( DOI )

  14. M.Riza、S.Tokura、M.Iwasaki、E.Yashima、A.Kishida、M.Akashi: Graft copolymers having hydrophobic backbone and hydrophilic branches. X. Preparation and properties of water‐dispersible polyanionic microspheres having poly(methacrylic acid) branches on their surfaces Journal of Polymer Science Part A: Polymer Chemistry . 1995.06; 33 (8): 1219-1225. ( DOI )

  15. Fujii T, Miyahara Y, Watanabe Y: Reduction of Glucose Interference in Biochemical Analyses Based on Infrared-Spectroscopy Bunseki Kagaku. 1995.06; 44 (6): 465-469.

  16. Yamamura J, Adachi T, Aoki N, Nakajima H, Nakamura R, Matsuda T: Precursor-product relationship between chicken vitellogenin and the yolk proteins: the 40 kDa yolk plasma glycoprotein is derived from the C-terminal cysteine-rich domain of vitellogenin II. Biochim Biophys Acta. 1995.06; 1244 (2-3): 384-394. ( PubMed )

  17. Tamamura H, Murakami T, Horiuchi S, Sugihara K, Otaka A, Takada W, Ibuka T, Waki M, Yamamoto N, Fujii N: Synthesis of protegrin-related peptides and their antibacterial and anti-human immunodeficiency virus activity. Chem Pharm Bull (Tokyo). 1995.05; 43 (5): 853-858. ( PubMed )

  18. Tamamura H, Otaka A, Nakamura J, Okubo K, Koide T, Ikeda K, Ibuka T, Fujii N: Disulfide bond-forming reaction using a dimethyl sulfoxide/aqueous HCl system and its application to regioselective two disulfide bond formation. Int J Pept Protein Res. 1995.04; 45 (4): 312-319. ( PubMed )

  19. Apel TW, Scherer A, Adachi T, Auch D, Ayane M, Reth M: The ribose 5-phosphate isomerase-encoding gene is located immediately downstream from that encoding murine immunoglobulin kappa. Gene. 1995.04; 156 (2): 191-197. ( PubMed )

  20. *Kohji Mitsubayashi, Kenji Yokoyama, Toshifumi Takeuchi, and Isao Karube: Flexible biosensor for glucose. ELECTROANALYSIS. 1995.01; 7 (1): 83-87.

  21. Tamamura H, Otaka A, Takada W, Terakawa Y, Yoshizawa H, Masuda M, Ibuka T, Murakami T, Nakashima H, Waki M, et al.: Solution-phase synthesis of an anti-human immunodeficiency virus peptide, T22 ([Tyr5,12,Lys7]-polyphemusin II), and the modification of Trp by the p-methoxybenzyl group of Cys during trimethylsilyl trifluoromethanesulfonate deprotection. Chem Pharm Bull (Tokyo). 1995.01; 43 (1): 12-18. ( PubMed )

  22. Ahn JY, Aoki N, Adachi T, Mizuno Y, Nakamura R, Matsuda T: Isolation and culture of bovine mammary epithelial cells and establishment of gene transfection conditions in the cells. Biosci Biotechnol Biochem. 1995.01; 59 (1): 59-64. ( PubMed )

  23. Yuichi Tada, Takahiro Adachi, Tsukasa Matsuda, Masayoshi Takahashi, Tasuhito Fujimura, Ryo Nakamura, Hiroaki Shimada: Reduction of allergenic proteins in transgenic rice by antisense strategy K.Oono, F.Takaiwa(eds.), Modification of gene expression and non-mendelian inheritance. National Institute of Agrobiological Resources, Japan. 1995; 313-324.

  24. Takahiro Adachi, Angelina M. Alvarez, Naohito Aoki, Ryo Nakamura, Tsukasa Matsuda, Virgilio V. Garcia: Screening of Rice Strains Deficient in 16-kDa Allergenic Protein Bioscience, Biotechnology, and Biochemistry. 1995; 59 (7): 1377-1378. ( DOI )

  25. Ito N, Knowles P F, Phillips S E: X-ray crystallographic studies of cofactors in galactose oxidase. Methods Enzymol. 1995; 258 235-262. ( PubMed )

  26. M.Yanagi、A.Kishida、T.Shimotakahara、H.Matsumoto、H.Nishijima、M.Akashi、T.Aikou: Study of soft tissue ingrowth into polyurethane sponges(PUS) and development of an artificial trachea made of PUS. Artif Organs Today. 1995; 5 (1): 29-40.

  27. Hosoya T, Kuriyama Y, Suzuki K.: Convenient Synthesis of Phthalides via Regioselective Baeyer-Villiger Oxidation of Benzocyclobutenones. Synlett. 1995; (6): 635-638. ( DOI )

  28. Yasuda K, Anazawa T, Ishiwata S : Microscopic analysis of the elastic properties of nebulin in skeletal myofibrils Biophys J. 1995; 68 598-608.

  29. Yasuda K, Umemura S, Takeda K: Concentration and fractionation of small particles in liquid by ultrasound Jpn J Appl Phys. 1995; 34 2715 -2720.

  30. Akira Otaka, Kengo Miyoshi, Terrence R. Burke, Jr., Peter P. Roller, Hideki Kubota, Hirokazu Tamamura & Nobutaka Fujii: Synthesis and Application of N-Boc-L-2-amino-4-(diethylphosphono)-4, 4-difluorobutanoic acid for Solid-Phase Synthesis of Nonhydrolyzable Phosphoserine Peptide Analogs. Tetrahedron Lett.. 1995; 36 927-930.

  31. Akira Otaka, Kengo Miyoshi, Peter P. Roller, Terrence R. Burke, Jr., Hirokazu Tamamura & Nobutaka Fujii: Practical Synthesis of Phosphopeptides using Dimethyl-protected Phosphoamino Acid Derivatives. J. Chem. Soc., Chem. Commun.. 1995; 387-389.

  32. Hosoya T, Hasegawa T, Kuriyama Y, Suzuki K: Stereospecificity in [2 + 2] Cycloaddition of Benzyne and Ketene Silyl Acetal. Tetrahedron Lett. 1995; 36 (19): 3377-3380. ( DOI )

  33. Suzuki K, Matsumoto T, Hosoya T.: Total Synthesis of the Gilvocarcins. J Synth Org Chem, Jpn. 1995; 53 (11): 1045-1054.

  34. Hosoya T, Hasegawa T, Kuriyama Y, Matsumoto T, Suzuki K.: [2 + 2] Cycloaddition of Benzyne and Ketene Silyl Acetal as an Efficient Route to Benzocyclobutenones. Synlett. 1995; (2): 177-179. ( DOI )

  35. Nobutaka Fujii, Kazuo Nakai, Hirokazu Tamamura, Akira Otaka, Norio Mimura, Yoshihisa Miwa, Tooru Taga, Yoshinori Yamamoto & Toshiro Ibuka: SN2' Ring Opening of Aziridines Bearing an α,β-Unsaturated Ester Group with Organocopper Reagents. A New Stereoselective Synthesis Route to (E)-Alkene Dipeptide Isosters. J. Chem. Soc., Perkin Trans.. 1995; 1 1359-1371.

  36. Akira Otaka, Kengo Miyoshi, Midori Kaneko, Hirokazu Tamamura, Nobutaka Fujii, Motoyoshi Nomizu, Terrence R. Burke, Jr. & Peter P. Roller: Development of Efficient Two-Step Deprotection Methodology for Dimethyl-Protected Phosphoamino Acid-Containing Peptide Resins and Its Application to the Practical Synthesis of Phosphopeptides. J. Org. Chem.. 1995; 60 3967-3974.

  37. Nagai K, Oubridge C, Ito N, Jessen T H, Avis J, Evans P: Crystal structure of the U1A spliceosomal protein complexed with its cognate RNA hairpin. Nucleic Acids Symp Ser. 1995; (34): 1-2. ( PubMed )

  38. Toshiro Ibuka, Kazuo Nakai, Hiromu Habashita, Yuka Hotta, Akira Otaka, Hirokazu Tamamura, Nobutaka Fujii, Norio Mimura, Yoshihisa Miwa, Tooru Taga, Yukiyasu Chounan & Yoshinori Yamamoto: Aza-Payne Rearrangement of Activated 2-Aziridinemethanols and 2,3-Epoxy Amines under Basic Conditions. J.Org.Chem.. 1995; 60 2044-2058.

  39. Kazuo Nakai, Toshiro Ibuka, Akira Otaka, Hirokazu Tamamura, Nobutaka Fujii & Yoshinori Yamamoto: A One-pot Aza-Payne Rearrangement-Epoxide Ring Opening Reaction of 2-Aziridinemethanols: A Regio- and Stereoselective Synthetic Route to Diastereomerically Pure 1,2-Amino Alcohols. Tetrahedron Lett.. 1995; 36 6247-6250.

  40. Yuichi Tada, Takahiro Adachi, Tsukasa Matsuda, Masayoshi Takahashi, Tasuhito Fujimura, Ryo Nakamura, Hiroaki Shimada: Reduction of allergenic proteins in transgenic rice by antisense strategy K.Oono, F.Takaiwa(eds.), Modification of gene expression and non-mendelian inheritance. National Institute of Agrobiological Resources, Japan. 1995; 313-324.

  1. Oubridge C, Ito N, Evans P R, Teo C H, Nagai K: Crystal structure at 1.92 A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin. Nature. 1994.12; 372 (6505): 432-438. ( PubMed , DOI )

  2. Y.Baba、H.Inoue、M.Tsuhako、T.Sawa、A.Kishida、M.Akashi: Evaluation of the Selective Binding Ability of Oligodeoxynucleotides to Poly(9-vinyladenine) Using Capillary Affinity Gel Electrophoresis. Analytical Sciences. 1994.12; 10 (6): 967-969. ( DOI )

  3. Tamamura H, Murakami T, Masuda M, Otaka A, Takada W, Ibuka T, Nakashima H, Waki M, Matsumoto A, Yamamoto N, et al.: Structure-activity relationships of an anti-HIV peptide, T22. Biochem Biophys Res Commun. 1994.12; 205 (3): 1729-1735. ( PubMed )

  4. Otaka A, Tamamura H, Terakawa Y, Masuda M, Koide T, Murakami T, Nakashima H, Matsuzaki K, Miyajima K, Ibuka T, et al.: Molecular parameters for the anti-human immunodeficiency virus activity of T22 ([Tyr5,12, Lys7]-polyphemusin II). Biol Pharm Bull. 1994.12; 17 (12): 1669-1672. ( PubMed )

  5. Shimizu T, Uenishi H, Teramura Y, Iwashiro M, Kuribayashi K, Tamamura H, Fujii N, Yamagishi H: Fine structure of a virus-encoded helper T-cell epitope expressed on FBL-3 tumor cells. J Virol. 1994.12; 68 (12): 7704-7708. ( PubMed )

  6. A.Kishida、Y.Ueno、I.Maruyama、M.Akashi: Immobilization of human thrombomodulin on biomaterials: evaluation of the activity of immobilized human thrombomodulin. Biomaterials. 1994.11; 15 (14): 1170-1174. ( DOI )

  7. *Kohji Mitsubayashi, Kenji Yokoyama, Toshifumi Takeuchi, and Isao Karube: Gas-phase biosensor for ethanol. ANALYTICAL CHEMISTRY. 1994.10; 66 (20): 3297-3302.

  8. Shibuya H, Kohu K, Yamada K, Barsoumian EL, Perlmutter RM, Taniguchi T: Functional dissection of p56lck, a protein tyrosine kinase which mediates interleukin-2-induced activation of the c-fos gene. Mol Cell Biol. 1994.09; 14 (9): 5812-5819. ( PubMed )

  9. A.Kishida、Y.Ueno、N.Fukudome、E.Yashima、I.Maruyama、M.Akashi: Immobilization of human thrombomodulin onto poly(ether urethane urea) for developing antithrombogenic blood-contacting materials Biomaterials. 1994.08; 15 (10): 848-852. ( DOI )

  10. *Kohji Mitsubayashi, Kenji Yokoyama, Toshifumi Takeuchi, Eiichi Tamiya and Isao Karube: Monitoring of sweat lactate. TRANSACTION OF THE MATERIALS RESEARCH SOCIETY OF JAPAN. 1994.08; 15a 429-432.

  11. Terashima M, Kim KM, Adachi T, Nielsen PJ, Reth M, Kohler G, Lamers MC: The IgM antigen receptor of B lymphocytes is associated with prohibitin and a prohibitin-related protein. EMBO J. 1994.08; 13 (16): 3782-3792. ( PubMed )

  12. Kim KM, Adachi T, Nielsen PJ, Terashima M, Lamers MC, Kohler G, Reth M: Two new proteins preferentially associated with membrane immunoglobulin D. EMBO J. 1994.08; 13 (16): 3793-3800. ( PubMed )

  13. N AOKI, M UJITA, H KURODA, M URABE, A NODA, T ADACHIL, R NAKAMURA, T MATSUDA: IMMUNOLOGICALLY CROSS-REACTIVE 57 KDA AND 53 KDA GLYCOPROTEIN ANTIGENS OF BOVINE-MILK FAT GLOBULE-MEMBRANE - ISOFORMS WITH DIFFERENT N-LINKED SUGAR CHAINS AND DIFFERENTIAL GLYCOSYLATION AT EARLY STAGES OF LACTATION BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. 1994.07; 1200 (2): 227-234.

  14. M.Yanagi、A.Kishida、T.Shimotakahara、H.Matsumoto、H.Nishijima、M.Akashi、T.Aikou: Experimental Study of Bioactive Polyurethane Sponge as an Artificial Trachea. ASAIO Journal . 1994.07; 40 (3): M412-M418.

  15. A.Kishida、Y.Ueno、I.Maruyama、M.Akashi: Immobilization of Human Thrombomodulin onto Biomaterials: Comparison of Immobilization Methods and Evaluation of Antithrombogenicity ASAIO Journal. 1994.07; 40 (3): M840-M845.

  16. Weeks BS, Nomizu M, Otaka A, Weston CA, Okusu A, Tamamura H, Matsumoto A, Yamamoto N, Fujii N: Lymphocytes and promonocytes attach to the synthetic [Tyr5,12, Lys7]- polyphemusin II peptide. Biochem Biophys Res Commun. 1994.07; 202 (1): 470-475. ( PubMed )

  17. Miyahara Y, Tsukada K, Watanabe Y: Long-Life Planar Oxygen Sensor Sensor Actuat B-Chem. 1994.06; 20 (2-3): 89-94.

  18. Ito N, Phillips S E, Yadav K D, Knowles P F: Crystal structure of a free radical enzyme, galactose oxidase. J Mol Biol. 1994.05; 238 (5): 794-814. ( PubMed )

  19. *Kohji Mitsubayashi, Masayasu Suzuki, Eiichi Tamiya, and Isao Karube: Analysis of metabolites in sweat as a measure of physical condition. ANALITICA CHIMICA ACTA. 1994.05; 289 27-34.

  20. A.Kishida、T.Furuzono、T.Ohshige、I.Maruyama、T.Matsumoto、H.Itoh、M.Murakami、M.Akashi: Study of the surface properties of ultrathin films of poly(dimethylsiloxane)‐polyamide multiblock copolymers Angewandte Makromolekulare Chemie . 1994.03; 220 (1): 89-97. ( DOI )

  21. Aoki N, Kuroda H, Urabe M, Taniguchi Y, Adachi T, Nakamura R, Matsuda T: Production and characterization of monoclonal antibodies directed against bovine milk fat globule membrane (MFGM). Biochim Biophys Acta. 1994.01; 1199 (1): 87-95. ( PubMed )

  22. JY AHN, K YAMAMOTO, N AOKI, T ADACHI, R NAKAMURA, T MATSUDA: EXPRESSION OF MILK PROTEIN CAT CHIMERIC GENES IN TRANSFECTED BOVINE AND MOUSE MAMMARY EPITHELIAL CELLS ANIMAL CELL TECHNOLOGY: BASIC & APPLIED ASPECTS, VOL 6. 1994; 259-263.

  23. Ohsaki A, Yan LT, Ito S, Edatsugi H, Iwata D, Komoda Y.: The isolation and in-vivo potent antitumor-activity of clerodane diterpenoid from the Oleoresin of the Brazilian medical plant, Copaifera-Langsdorfii Desfon BIOORG MED CHEM LETT. 1994; 4 (24): 2889-2892.

  24. Hosoya T, Takashiro E, Matsumoto T, Suzuki K.: Total Synthesis of the Gilvocarcins. J Am Chem Soc. 1994; 116 (3): 1004-1015. ( DOI )

  25. Hosoya T, Takashiro E, Matsumoto T, Suzuki K.: First Total Synthesis of BE-12406 A. Tetrahedron Lett. 1994; 35 (26): 4591-4594. ( DOI )

  26. M.Riza、S.Tokura、A.Kishida、M.Akashi: Graft copolymers having a hydrophhobic backbone and hydrophilic branches. Part IX. Preparation of water-dispersible microspheres having polycationic branches on their surfaces. New Polymeric Materials . 1994; 4 (3): 189-198.

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  31. Toshiro Ibuka, Keisuke Suzuki, Hiromu Habashita, Akira Otaka, Hirokazu Tamamura, Norio Mimura, Yoshihisa Miwa, Tooru Taga & Nobutaka Fujii: (E)-Stereoselective Synthesis of Vinylglycines from (R)-Serine via Organocopper-BF3 and Related Reagents. J. Chem. Soc., Chem. Commun.. 1994; 2151-2152.

  1. Y.Inami、K.Nakamura、H.Ishiba、A.Kishida、M.Akashi: Affinity Electrophoresis of Nucleic Acids. The Interaction between Water Soluble Polymers Having Malachite Green and Double-stranded DNA. Nucleic Acids Symposium Series. 1993.12; 29 77-78.

  2. Y.Baba、R.Tomosaki、M.Tsuhako、T.Sawa、Y.Inami、A.Kishida、M.Akashi: Detection of mismatch positions on the DNA-polyvinyladenine hybrids using capillary affinity gel electrophoresis. Nucleic Acids Symposium Series. 1993.12; 29 81-82.

  3. McPherson M J, Stevens C, Baron A J, Ogel Z B, Seneviratne K, Wilmot C, Ito N, Brocklebank I, Phillips S E, Knowles P F: Galactose oxidase: molecular analysis and mutagenesis studies. Biochem Soc Trans. 1993.08; 21 ( Pt 3) (3): 752-756. ( PubMed )

  4. Evans P R, Oubridge C, Jessen T H, Li J, Teo C H, Pritchard C, Ito N, Nagai K: Model of the interaction between the UI A small nuclear ribonucleoprotein and UI small nuclear RNA stem/loop II. Biochem Soc Trans. 1993.08; 21 ( Pt 3) (3): 605-609. ( PubMed )

  5. Tamamura H, Kuroda M, Masuda M, Otaka A, Funakoshi S, Nakashima H, Yamamoto N, Waki M, Matsumoto A, Lancelin JM, et al.: A comparative study of the solution structures of tachyplesin I and a novel anti-HIV synthetic peptide, T22 ([Tyr5,12, Lys7]-polyphemusin II), determined by nuclear magnetic resonance. Biochim Biophys Acta. 1993.05; 1163 (2): 209-216. ( PubMed )

  6. Tamamura H, Ikoma R, Niwa M, Funakoshi S, Murakami T, Fujii N: Antimicrobial activity and conformation of tachyplesin I and its analogs. Chem Pharm Bull (Tokyo). 1993.05; 41 (5): 978-980. ( PubMed )

  7. Tamamura H, Nakamura J, Noguchi K, Funakoshi S, Fujii N: Acceleration of the N alpha-deprotection rate by the addition of m-cresol to diluted methanesulfonic acid and its application to the Z(OMe)-based solid-phase syntheses of human pancreastatin-29 and magainin 1. Chem Pharm Bull (Tokyo). 1993.05; 41 (5): 954-957. ( PubMed )

  8. T.Furuzono、E.Yashima、A.Kishida、I.Mruyama、T.Matsumoto、M.Akashi: A novel biomaterial: Poly(dimethylsiloxane)-polyamide multiblock copolymer I. Synthesis and evaluation of blood compatibility Journal of Biomaterials Science, Polymer Edition. 1993.04; 5 (1-2): 89-98. ( DOI )

  9. *Kohji Mitsubayashi, Kenji Yokoyama, Toshifumi Takeuchi, Eiichi Tamiya and Isao Karube: Flexible conductimetric sensor. ANALYTICAL CHEMISTRY. 1993.04; 65 (24): 3586-3590.

  10. M.Riza、I.Capek、A.Kishida、M.Akashi: Graft Copolymers Having Hydrophhobic Backbone and Hydrophilic Branches, 8. Effect of Temperature on the Dispersion Copolymerization of Poly(ethylene glycol) Macromonomer with Styrene. Angewandte Makromolekulare Chemie. 1993.03; 206 (1): 69-75. ( DOI )

  11. Adachi T, Izumi H, Yamada T, Tanaka K, Takeuchi S, Nakamura R, Matsuda T: Gene structure and expression of rice seed allergenic proteins belonging to the alpha-amylase/trypsin inhibitor family. Plant Mol Biol. 1993.01; 21 (2): 239-248. ( PubMed )

  12. Ito S, Ando S, Yamaguchi K, Funayama N, Yamamoto T, Kuroiwa Y, Kubota T, Komoda Y.: Preparation and evaluation of the antiaggregating and vasodilating activities of the novel 3-nitro-4(3H)-quinazolone derivatives BIOORG MED CHEM LETT. 1993; 3 (4): 611-614.

  13. Sato N, Sakamaki K, Terada N, Arai K, Miyajima A: Signal transduction by the high-affinity GM-CSF receptor: two distinct cytoplasmic regions of the common beta subunit responsible for different signaling EMBO J. 1993; 12 (11): 4181-4189. ( PubMed )

  14. Sato N, Caux C, Kitamura T, Watanabe Y, Arai K, Banchereau J, Miyajima A: Expression and factor-dependent modulation of the interleukin-3 receptor subunits on human hematopoietic cells Blood. 1993; 82 (3): 752-761. ( PubMed )

  15. Ishiwata S, Anazawa T, Yasuda K, Fujita T, Fukuda N, Shimizu H : Spontaneous tension oscillation (SPOC) of muscle fibers myofibrils. Minimum requirements for SPOC Adv Exp Med Biol. 1993; 332 545-556.

  16. Ishiwata S, Yasuda K: Mechano-chemical coupling in spontaneous oscillatory contraction of muscle Phase Transitions . 1993; 45 105-136.

  17. Toshiro Ibuka, Tooru Taga, Hiromu Habashita, Kazuo Nakai, Hirokazu Tamamura, Nobutaka Fujii, Yukiyasu Chounan, Hisao Nemoto & Yoshinori Yamamoto : Syn-SN2' Pathway in the Reaction of Certain γ-(Mesyloxy)-α,β-Enoates with RCu(CN)MgX.BF3 Reagents. Importance of MgX and Bulky R Group upon the Diastereoselectivity. J. Org. Chem.. 1993; 58 1207-1214.

  18. Hirokazu Tamamura, Akira Otaka, Junko Nakamura, Kaori Okubo, Takaki Koide, Kyoko Ikeda & Nobutaka Fujii.: Disulfide Bond Formation in S-Acetamidomethyl Cysteine-Containing Peptides by the Combination of Silver Trifluoromethanesulfonate and Dimethylsulfoxide / Aqueous HCl. Tetrahedron Lett.. 1993; 34 4931-4934.

  1. A.Kishida、M.Takatsuka、T.Matsuda: RGD-ALB Conjugate: Expression of Tissue Regeneration Activity. Biomaterials. 1992.12; 13 (13): 924-930. ( DOI )

  2. Masuda M, Nakashima H, Ueda T, Naba H, Ikoma R, Otaka A, Terakawa Y, Tamamura H, Ibuka T, Murakami T, et al.: A novel anti-HIV synthetic peptide, T-22 ([Tyr5,12,Lys7]-polyphemusin II). Biochem Biophys Res Commun. 1992.12; 189 (2): 845-850. ( PubMed )

  3. NAKATANI TAKESHI、KISHIDA AKIO、MATSUDA TAKEHISA、SAKAKI MASAYUKI、GOTO MASAHIRO、TAENAKA YOSHIYUKI、KINOSHITA MASAYUKI、AKACI HARUHIKO、MASUZAWA TORU、BABA YUZO、ARAKI KENJI、INOUE KAZUSHIGE、ANAI HIROFUMI、MATSUO YOSHIAKI、TAKANO HISATERU: A Bioartificial Ventricle Used as a Totally Implantable Circulatory Assist Device ASAIO Journal. 1992.07; 38 (3): M167-M170.

  4. M.Takatsuka、A.Kishida、T.Matsuda: Preparation of an RGD-ALB Conjugate: In Vitro Analysis of Cellular Responses. ASAIO Journal. 1992.07; 38 (3): M275-M278.

  5. T.Matsuda、A.Kishida、H.Ebato、Y.Okahata: Novel Instrumentation Monitoring In Situ Platelet Adhesivity with a Quartz Crystal Microbalance. ASAIO Journal . 1992.07; 38 (3): M171-M173.

  6. Shibuya H, Yoneyama M, Ninomiya-Tsuji J, Matsumoto K, Taniguchi T: IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signaling pathways: demonstration of a novel role for c-myc. Cell. 1992.07; 70 (1): 57-67. ( PubMed )

  7. Shibuya H, Irie K, Ninomiya-Tsuji J, Goebl M, Taniguchi T, Matsumoto K: New human gene encoding a positive modulator of HIV Tat-mediated transactivation. Nature. 1992.06; 357 (6380): 700-702. ( PubMed , DOI )

  8. Izumi H, Adachi T, Fujii N, Matsuda T, Nakamura R, Tanaka K, Urisu A, Kurosawa Y: Nucleotide sequence of a cDNA clone encoding a major allergenic protein in rice seeds. Homology of the deduced amino acid sequence with members of alpha-amylase/trypsin inhibitor family. FEBS Lett. 1992.05; 302 (3): 213-216. ( PubMed )

  9. Miyahara Y: Characterization of Sputtered Yttria-Stabilized Zirconia Thin-Film and Its Application to a Metal-Insulator-Semiconductor Structure J Appl Phys. 1992.03; 71 (5): 2309-2314.

  10. Hatakeyama M, Kawahara A, Mori H, Shibuya H, Taniguchi T: c-fos gene induction by interleukin 2: identification of the critical cytoplasmic regions within the interleukin 2 receptor beta chain. Proc Natl Acad Sci U S A. 1992.03; 89 (6): 2022-2026. ( PubMed )

  11. Akio Kishida、Kazuhiro Mishima、Eugene Corretge、Hikaru Konishi、Yoshito Ikada: Interactions of poly(ethylene glycol)-grafted cellulose membranes with proteins and platelets Biomaterials. 1992.02; 13 (2): 113-118. ( DOI )

  12. Ito S, Yamaguchi K, Komoda Y: Structural confirmation of the nitration product of the 1(2H)-phthalazinone as the 2-Nitro-1(2H)- phthalazinone CHEM PHARM BULL. 1992; 40 (12): 3327-3329.

  13. Ito N, Phillips S E, Stevens C, Ogel Z B, McPherson M J, Keen J N, Yadav K D, Knowles P F: Three-dimensional structure of galactose oxidase: an enzyme with a built-in secondary cofactor. Faraday Discuss. 1992; (93): 75-84. ( PubMed )

  14. Anazawa T, Yasuda K, Ishiwata S: Spontaneous oscillation of tension and sarcomere length in skeletal myofibrils Biophys J. 1992; 61 1099-1108.

  15. Matsumoto T, Hosoya T, Suzuki K.: Total Synthesis and Absolute Stereochemical Assignment of Gilvocarcin M. J Am Chem Soc. 1992; 114 (9): 3568-3570. ( DOI )

  1. A.Kishida、H.Iwata、Y.Tamada、Y.Ikada: Cell Behavior on Polymer Surfaces Grafted with Nonionic and Ionic Monomers. Biomaterials. 1991.10; 12 (8): 786-792. ( DOI )

  2. Adachi T, Yamagata H, Tsukagoshi N, Udaka S: Repression of the cell wall protein gene operon in Bacillus brevis 47 by magnesium and calcium ions. J Bacteriol. 1991.07; 173 (13): 4243-4245. ( PubMed )

  3. Miyahara Y, Tsukada K, Miyagi H, Simon W: Urea Sensor Based on an Ammonium-Ion-Sensitive Field-Effect Transistor Sensor Actuat B-Chem. 1991.04; 3 (4): 287-293.

  4. S.Yoshioka、A.Kishida、S.Izumikawa、Y.Aso、Y.Takeda: Base-Induced Polymer Hydrolysis in Poly(β-hydroxybutyrate/β-hydroxyvalerate) Matrices. Journal of Controlled Release. 1991.03; 16 (3): 341-347. ( DOI )

  5. Ito N, Phillips S E, Stevens C, Ogel Z B, McPherson M J, Keen J N, Yadav K D, Knowles P F: Novel thioether bond revealed by a 1.7 A crystal structure of galactose oxidase. Nature. 1991.03; 350 (6313): 87-90. ( PubMed , DOI )

  6. Y.Uyama、H.Inoue、K.Ito、A.Kishida、Y.Ikada: Comparison of Different Methods for Contact Angle Measurement Journal of Colloid and Interface Science. 1991.01; 141 (1): 275-279. ( DOI )

  7. Adachi T, Sakakibara T, Yamagata H, Tsukagoshi N, Udaka S: Analysis by deletion and site-directed mutagenesis of promoters of the cell wall protein gene operon in Bacillus brevis 47. Agric Biol Chem. 1991.01; 55 (1): 189-194. ( PubMed )

  8. ITO N, NAKAMURA H, SUMIKAWA H, NAGASHIMA N, ARATA Y, NISHIMURA Y: STRUCTURE OF A DNA OCTAMER, D(CCTTAAGG)2 OBTAINED BY RESTRAINED MOLECULAR-DYNAMICS BASED ON RAMAN AND NMR DATA JOURNAL OF MOLECULAR STRUCTURE. 1991.01; 242 119-133. ( DOI )

  9. Kitamura T, Sato N, Arai K, Miyajima A: Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors Cell. 1991; 66 (6): 1165-1174. ( PubMed )

  10. Matsumoto T, Hosoya T, Suzuki K.: O->C-Glycoside Rearrangement of Resorcinol Derivatives. Versatile Intermediates in the Synthesis of Aryl C-Glycosides. Synlett. 1991; (10): 709-711. ( DOI )

  11. Ishiwata S, Okamura N, Shimizu H, Anazawa T, Yasuda K: Spontaneous oscillatory contraction (SPOC) of sarcomeres in skeletal muscle Adv Biophys. 1991; 27 227-235.

  12. Miyahara Y, Simon W: Comparative-Studies between Ion-Selective Field-Effect Transistors and Ion-Selective Electrodes with Polymeric Membranes Electroanalysis. 1991; 3 (4-5): 287-292.

  13. Matsumoto T, Hosoya T, Katsuki M, Suzuki K.: New Efficient Protocol for Aryne Generation. Selective Synthesis of Differentially Protected 1,4,5-Naphthalenetriols. Tetrahedron Lett. 1991; 32 (46): 6735-6736. ( DOI )

  1. Miyasaka K, Funakoshi A, Kitani K, Tamamura H, Funakoshi S, Fujii N: Inhibitory effect of pancreastatin on pancreatic exocrine secretions. Pancreastatin inhibits central vagal nerve stimulation. Gastroenterology. 1990.12; 99 (6): 1751-1756. ( PubMed )

  2. Ito N, Keen J N, Knowles P F, McPherson M J, Phillips S E, Stevens C, Yadav K D: Structural analysis of galactose oxidase. Biochem Soc Trans. 1990.10; 18 (5): 931-932. ( PubMed )

  3. Tsukada K, Miyahara Y, Shibata Y, Miyagi H: An Integrated Chemical Sensor with Multiple Ion and Gas Sensors Sensor Actuat B-Chem. 1990.10; 2 (4): 291-295.

  4. T.Akizawa、K.Kino、E.Kinugasa、S.Koshikawa、Y.Ikada、A.Kishida、Y.Hatanaka、K.Imamura: Clinical Effects of a Polyethylene Glycol Grafted Cellulose Membrane on Thrombogenicity and Biocompatibility During Hemodialysis. ASAIO Transactions. 1990.07; 36 (3): M640-M642.

  5. Shibuya H, Yoneyama M, Nakamura Y, Harada H, Hatakeyama M, Minamoto S, Kono T, Doi T, White R, Taniguchi T: The human interleukin-2 receptor beta-chain gene: genomic organization, promoter analysis and chromosomal assignment. Nucleic Acids Res. 1990.07; 18 (13): 3697-3703. ( PubMed )

  6. A.Kishida、J.Dressman、S.Yoshioka、Y.Aso、Y.Takeda: Some Determinants of Morphology and Release Rate from Poly-l-lactic Acid Microspheres Journal of Controlled Release . 1990.07; 13 (1): 83-89. ( DOI )

  7. Tamamura H, Ohta M, Yoshizawa K, Ono Y, Funakoshi A, Miyasaka K, Tateishi K, Jimi A, Yajima H, Fujii N, et al.: Isolation and characterization of a tumor-derived human protein related to chromogranin A and its in vitro conversion to human pancreastatin-48. Eur J Biochem. 1990.07; 191 (1): 33-39. ( PubMed )

  8. Durselen LFJ, Oesterle U, Schuppisser S, Pham HV, Miyahara Y, Morf WE, Simon W: New Solid-State Contact for Ion-Selective Liquid Membrane Electrodes Chimia. 1990.06; 44 (6): 214-215.

  9. Miyasaka K, Funakoshi A, Yasunami Y, Nakamura R, Kitani K, Tamamura H, Funakoshi S, Fujii N: Rat pancreastatin inhibits both pancreatic exocrine and endocrine secretions in rats. Regul Pept. 1990.04; 28 (2): 189-198. ( PubMed )

  10. Miyasaka K, Funakoshi A, Kitani K, Tamamura H, Fujii N, Funakoshi S: The importance of the C-terminal amide structure of rat pancreastatin to inhibit pancreatic exocrine secretion. FEBS Lett. 1990.04; 263 (2): 279-280. ( PubMed )

  11. Adachi T, Yamagata H, Tsukagoshi N, Udaka S: Use of both translation initiation sites of the middle wall protein gene in Bacillus brevis 47. J Bacteriol. 1990.01; 172 (1): 511-513. ( PubMed )

  12. Manz A, Miyahara Y, Miura J, Watanabe Y, Miyagi H, Sato K: Design of an Open-Tubular Column Liquid Chromatograph Using Silicon Chip Technology Sensor Actuat B-Chem. 1990.01; 1 (1-6): 249-255.

  13. Ito S, Azuma H, Funayama N, Kubota T, Sekizaki-Ohyama S, Ishikawa M: Studies on Vasoactive Compounds.III. Preparation and Antiaggregating Activitys of 1-Acetoxyphthalazine Derivatives and 2-methylsulfonyl-1(2H)-phthalazone derivatives Report Inst. Med. Dent. Engin.. 1990; 24 41-48.

  14. Matsumoto T, Hosoya T, Suzuki K.: Improvement in O->C-Glycoside Rearrangement Approach to C-Aryl Glycosides: Use of 1-O-Acetyl Sugar as Stable but Efficient Glycosyl Donor. Tetrahedron Lett. 1990; 31 (32): 4629-4632. ( DOI )

  15. Akihiro Funakoshi, Kyoko Miyasaka, Kenichi Kitani, Susumu Funakoshi, Hirokazu Tamamura, Nobutaka Fujii, Itsuro Nakano & Kazuhiko Tatemoto: Comparative Effects of Mammalian Pancreastatin on the Pancreatic Exocrine Secretion. Japanese J. Pysiol.. 1990; 39 901-905.

  1. Tsukada K, Miyahara Y, Miyagi H: Platinum-Platinum Oxide Gate Ph Isfet Japanese Journal of Applied Physics Part 1-Regular Papers Short Notes & Review Papers. 1989.12; 28 (12): 2450-2453.

  2. Tateishi K, Funakoshi A, Wakasugi H, Iguchi H, Shinozaki H, Abe M, Funakoshi S, Tamamura H, Yajima H, Matsuoka Y: Plasma pancreastatin-like immunoreactivity in various diseases. J Clin Endocrinol Metab. 1989.12; 69 (6): 1305-1308. ( PubMed )

  3. Tateishi K, Funakoshi A, Jimi A, Funakoshi S, Tamamura H, Yajima H, Matsuoka Y: High plasma pancreastatinlike immunoreactivity in a patient with malignant insulinoma. Gastroenterology. 1989.11; 97 (5): 1313-1318. ( PubMed )

  4. Shibuya H, Taniguchi T: Identification of multiple cis-elements and trans-acting factors involved in the induced expression of human IL-2 gene. Nucleic Acids Res. 1989.11; 17 (22): 9173-9184. ( PubMed )

  5. Funakoshi S, Tamamura H, Ohta M, Yoshizawa K, Funakoshi A, Miyasaka K, Tateishi K, Tatemoto K, Nakano I, Yajima H, et al.: Isolation and characterization of a tumor-derived human pancreastatin-related protein. Biochem Biophys Res Commun. 1989.10; 164 (1): 141-148. ( PubMed )

  6. Tsukada K, Sebata M, Miyahara Y, Miyagi H: Long-Life Multiple-Isfets with Polymeric Gates Sensors and Actuators. 1989.07; 18 (3-4): 329-336.

  7. A.Kishida、S.Yoshioka、Y.Takeda、M.Uchiyama: Formulation-assisted Biodegradable Polymer Matrices Chemical＆pharmaceutical bulletin. 1989.07; 37 (7): 1954-1956. ( DOI )

  8. T.Akizawa、K.Kino、S.Koshikawa、Y.Ikada、A.Kishida、K.Imamura、M.Yamashita: Efficiency and Biocompatibility of a Poly(ethylene glycol) Grafted Cellulosic Membrane during Hemodialysis. Transactions - American Society for Artificial Internal Organs. 1989.07; 35 (3): 333-335.

  9. J.Isobe、H.Mizuno、S.Matsunobe、Y.Shimizu、Y.Ikada、A.Kishida: A New Type of Low Blood Flow ECCO2 Using a Hemodialysis System in Apenic States. Transactions - American Society for Artificial Internal Organs. 1989.07; 35 (3): 638-639.

  10. Funakoshi A, Jimi A, Yasunami Y, Tateishi K, Funakoshi S, Tamamura H, Yajima H: Bioactivity of human pancreastatin and its localization in pancreas. Biochem Biophys Res Commun. 1989.03; 159 (3): 913-918. ( PubMed )

  11. Adachi T, Yamagata H, Tsukagoshi N, Udaka S: Multiple and tandemly arranged promoters of the cell wall protein gene operon in Bacillus brevis 47. J Bacteriol. 1989.02; 171 (2): 1010-1016. ( PubMed )

  12. Funakoshi A, Miyasaka K, Kitani K, Tamamura H, Funakoshi S, Yajima H: Bioactivity of synthetic C-terminal fragment of rat pancreastatin on endocrine pancreas. Biochem Biophys Res Commun. 1989.02; 158 (3): 844-849. ( PubMed )

  13. AZUMA H, SUGIMOTO-TOKUSHIMA M, TANAKA K, IKENOUE Y, ITO S, ISHIKAWA M: ALPHA-1-ADRENOCEPTOR ANTAGONIST ACTIVITY OF NOVEL PYRIMIDINE-DERIVATIVES (SHI437 AND IK29) IN RABBIT AORTA AND TRIGONE OF THE BLADDER BRIT J PHARMACOL. 1989; 96 (4): 1000-1006.

  14. Nobutaka Fujii, Akira Otaka, Toshihiro Watanabe, Akira Okamachi, Hirokazu Tamamura, Haruaki Yajima, Yoshimasa Inagaki, Motoyoshi Nomizu & Katsuhiko Asano: Silver Trifluoromethanesulphonate as an S-Deprotecting Reagent for the Synthesis of Cystine Peptides. J. Chem. Soc., Chem. Commun.. 1989; 283-284.

  15. Shibuya H, Yoneyama M, Taniguchi T: Involvement of a common transcription factor in the regulated expression of IL-2 and IL-2 receptor genes. Int Immunol. 1989; 1 (1): 43-49. ( PubMed )

  1. H.Iwata、A.Kishida、M.Suzuki、Y.Hata、Y.Ikada: Oxidation of Polyethylene surface by Corona Discharge Treatment and The Subsequent Graft Polymerization. Journal of Polymer Science Part A: Polymer Chemistry . 1988.11; 26 (12): 3309-3322. ( DOI )

  2. Funakoshi A, Miyasaka K, Nakamura R, Kitani K, Funakoshi S, Tamamura H, Fujii N, Yajima H: Bioactivity of synthetic human pancreastatin on exocrine pancreas. Biochem Biophys Res Commun. 1988.11; 156 (3): 1237-1242. ( PubMed )

  3. Miyahara Y, Tsukada K, Miyagi H: Field-Effect Transistor Using a Solid Electrolyte as a New Oxygen Sensor J Appl Phys. 1988.04; 63 (7): 2431-2434.

  4. Tsuboi A, Uchihi R, Adachi T, Sasaki T, Hayakawa S, Yamagata H, Tsukagoshi N, Udaka S: Characterization of the genes for the hexagonally arranged surface layer proteins in protein-producing Bacillus brevis 47: complete nucleotide sequence of the middle wall protein gene. J Bacteriol. 1988.02; 170 (2): 935-945. ( PubMed )

  5. ITO S, KOMODA Y, SEKIZAKI S, AZUMA H, ISHIKAWA M.: STUDIES ON VASOACTIVE HETEROCYCLIC-COMPOUNDS - PREPARATION AND EVALUATION OF THE HYPOTENSIVE AND ANTIAGGREGATING ACTIVITIES OF PHTHALAZINOL NITRATES CHEM PHARM BULL. 1988; 36 (7): (7): 2669-2672.

  6. Susumu Funakoshi, Hirokazu Tamamura, Nobutaka Fujii, Kumi Yoshizawa, Haruaki Yajima, Kyoko Miyasaka, Akihiro Funakoshi, Mitsuhiro Ohta, Yoshimasa Inagaki & Louis A. Carpino: Combination of a New Amide-precursor Reagent and Trimethylsilyl Bromide Deprotection for the Fmoc-based Solid Phase Synthesis of Human Pancreastatin and One of its Fragment. J. Chem. Soc., Chem. Commun.. 1988; 1588-1590.

  1. Teravaninthorn U, Miyahara Y, Moriizumi T: The Suitability of Ta2o5 as a Solid-State Ion-Sensitive Membrane Japanese Journal of Applied Physics Part 1-Regular Papers Short Notes & Review Papers. 1987.12; 26 (12): 2116-2120.

  2. Fujita T, Shibuya H, Hotta H, Yamanishi K, Taniguchi T: Interferon-beta gene regulation: tandemly repeated sequences of a synthetic 6 bp oligomer function as a virus-inducible enhancer. Cell. 1987.05; 49 (3): 357-367. ( PubMed )

  3. Yamagata H, Adachi T, Tsuboi A, Takao M, Sasaki T, Tsukagoshi N, Udaka S: Cloning and characterization of the 5' region of the cell wall protein gene operon in Bacillus brevis 47. J Bacteriol. 1987.03; 169 (3): 1239-1245. ( PubMed )

  4. Teravaninthorn U, Miyahara Y, Moriizumi T: Influence of Reactive Gas-Pressure on the Properties of Thin-Film Ta2o5 Japanese Journal of Applied Physics Part 1-Regular Papers Short Notes & Review Papers. 1987.03; 26 (3): 347-351.

  5. Maruyama M, Shibuya H, Harada H, Hatakeyama M, Seiki M, Fujita T, Inoue J, Yoshida M, Taniguchi T: Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering. Cell. 1987.01; 48 (2): 343-350. ( PubMed )

  1. Miyahara Y: Biochemical FET Journal of the Society of Instrument and Control Engineers. 1986.11; 25 (11): 996-997.

  2. Fujita T, Shibuya H, Ohashi T, Yamanishi K, Taniguchi T: Regulation of human interleukin-2 gene: functional DNA sequences in the 5' flanking region for the gene expression in activated T lymphocytes. Cell. 1986.08; 46 (3): 401-405. ( PubMed )

  3. M. Suzuki、A. Kishida、H. Iwata、Y. Ikada: Graft Copolymerization of Acrylamide onto a Polyethylene Surface Pretreated with a Glow Discharge Macromolecules. 1986.07; 19 (7): 1804-1808. ( DOI )

  4. Moriizumi T, Miyahara Y: Proceeding to Biological-Systems .1. Application of Sensors to Biological-Systems Denki Kagaku. 1986.06; 54 (6): 454-458.

  5. Hiro-omi Homma, Kohji Mitsubayashi: Analysis of stable crack growth in GFRP. Ed. H.P. Rossmanith, Structure Failure, Product Liability and Technical Insurance. 1986.02; 580-590.

  1. Moriizumi T, Miyahara Y, Shiokawa S: Biosensor OYOBUTURI. 1985.02; 54 (2): 98-114.

  2. Miyahara Y, Moriizumi T, Ichimura K: Integrated Enzyme Fets for Simultaneous Detections of Urea and Glucose Sensors and Actuators. 1985; 7 (1): 1-10.

  1. SUGIMOTO A, TANAKA H, EGUCHI Y, ITO S, TAKASHIMA Y, ISHIKAWA M.: 7-(ETHOXYCARBONYL)-6,8-DIMETHYL-2-PHENYL-1(2H)-PHTHALAZINONE DERIVATIVES - SYNTHESIS AND INHIBITORY EFFECTS ON PLATELET-AGGREGATION J MED CHEM. 1984; 27 (10): 1300-1305.

  2. SUGIMOTO A, ITO S, EGUCHI Y, TANAKA H, TAKASHIMA Y, ISHIKAWA M.: SYNTHESIS AND INHIBITORY EFFECTS ON PLATELET-AGGREGATION OF PHTHALAZINONE DERIVATIVES EUR J MED CHEM. 1984; 19 (3): 223-228.

  1. AZUMA H, TAKASHIMA Y, KATSUURA Y, et al.: PHARMACOLOGICAL PROPERTIES OF A NOVEL QUINAZOLINONE DERIVATIVE, 3-(2-CHLOROPHENYL)-6-ETHOXYCARBONYL-5,7-DIMETHYL-2-(N-METHYLCARBAMOYLOXYMETHYL)-4(3H)-QUINAZOLINONE (EG1088) - MECHANISM OF VASODILATING ACTION J PHARMACOBIO-DYNAM. 1983; 6 (3): (3): S58.

  2. Miyahara Y, Moriizumi T, Shiokawa S, Matsuoka H, Karube I, Suzuki S: Micro Urea Sensor Using Semiconductor and Enzyme Immobilizing Technologies Nippon Kagaku Kaishi. 1983; (6): 823-830.

  1. ISHIKAWA M, AZUMA H, EGUCHI Y, SUGIMOTO A, ITO S, TAKASHIMA Y, EBISAWA H, MORIGUVHI, KOTOKU I, SUZUKI H: NEW HYPOTENSIVE AGENTS CHEM PHARM BULL. 1982; 30 (2): 744-749.

  2. ISHIKAWA M, AZUMA H, EGUCHI Y, ITO S, TAKASHIMA Y, EBISAWA H, MORIGUVHI S, NAITO T, KOTOKU I: STRUCTURE-ACTIVITY-RELATIONSHIPS AND PHARMACOLOGICAL PROPERTIES OF A NEW HYPOTENSIVE AGENT (EG-1088) J PHARMACOBIO-DYNAM. 1982; 5 (4): S55.

  3. Matsuoka H, Karube I, Kawana Y, Suzuki S, Miyahara Y, Moriizumi T: Semiconductor Biosensor Modeled on Taste Cell Denki Kagaku. 1982; 50 (10): 856-857.

  1. MAEDA M, ITO S, KOJIMA M: 1-2 MOLAR ADDUCTS IN REACTION OF 5-PHENYLTHIAZOLE AND DIMETHYL ACETYLENEDICARBOXYLATE TETRAHEDRON LETT. 1976; 38 3463-3466.

  1. 大石 由美子: 【骨格筋の再生・維持・適応メカニズムの新知見-最先端研究がもたらしたパラダイムシフト】免疫細胞による筋再生制御 医学のあゆみ. 2024.06; 289 (10): 731-735. ( 医中誌 )

  2. 石田 遼太郎, ナセデン ムニラ, 市川 健太, 飯谷 健太, 三林 浩二: バイオ蛍光による経皮エタノールガス動画像化と手腕部位での応用評価 Journal of Advanced Science. 2024.04; 36 36301-1-36301-3.

  3. 竹田直也，土戸優志，飯谷健太，三林浩二: 酵素を内包して気相で機能する高分子ファイバーからなる生体ガスセンサの開発 Colloid & Interface Communications. 2024.03; 49 (1): 16-18.

  4. 丹羽　節，田原　強，C. E. Chase, F. G. Fang, 中岡貴義, 入江さつき, 林中恵美 ,和田康弘 , 向井英史, 増富健吉, 渡辺恭良, 崔　翼龍，細谷孝充: 脳膠芽腫のコンパニオン診断用PETトレーサーとしての[#U11#URC]エリブリンの合成 JSMI Report（日本分子イメージング学会機関誌）. 2024.02; 17 (1): 30-33.

  5. 丹羽　節, 喜井　勲, 細谷孝充: clickable光親和性標識プローブを用いた標的分子同定 実験医学増刊「あなたのラボから薬を生み出す　アカデミア創薬の実践」（善光龍哉, 辻川和丈 編）. 2024.01; 42 (2): 205-211.

  1. Yang Wenqian, Miyazaki Takuya, Nakagawa Yasuhiro, Boonstra Eger, Masuda Keita, Nakashima Yuki, Chen Pengwen, Mixich Lucas, Barthelmes Kevin, Matsumoto Akira, Mi Peng, Uchida Satoshi, Cabral Horacio: Block catiomers with flanking hydrolyzable tyrosinate groups enhance in vivo mRNA delivery via pi-pi stacking-assisted micellar assembly SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS. 2023.12; 24 (1): 2170164. ( PubMed , DOI )

  2. 玉村 啓和: HIVの研究を基盤とした抗SARS-CoV-2剤の創製 MEDCHEM NEWS. 2023.11; 33 (4): 187-192.

  3. 飯谷 健太, 堀口 勇貴, 藤田 博之, 張 耿, 當麻 浩司, 三林 浩二: 代謝モニタリングのための生化学式蛍光ガスセンサの研究 化学とマイクロ・ナノシステム. 2023.10; 22 (2): 26-29.

  4. Riki Shinohara, Yuuki Hayakawa, Kenta Iitani, and Kohji Mitsubayashi: Image-based parallel measurement of alcohol metabolism-related ethanol and acetaldehyde in exhaled air Journal of Advanced Sciences. 2023.09; 35 35301-1-35301-3. ( DOI )

  5. Kobayakawa Takuya, Amano Masayuki, Nakayama Miyuki, Tsuji Kohei, Ishii Takahiro, Miura Yutaro, Shinohara Kouki, Yamamoto Kenichi, Matsuoka Masao, Tamamura Hirokazu: Development of anti-HBV agents targeting HBV capsid proteins RSC MEDICINAL CHEMISTRY. 2023.08; 14 (10): 1973-1980. ( PubMed , DOI )

  6. 岸田晶夫: 組織再生医療の外科・代謝栄養学への応用の可能性 外科と代謝・栄養. 2023.08; 57 (4): 95-99.

  7. 花園祐矢: 高分解能中性子構造解析によるペプチド平面の再検討 生物物理. 2023.08; 63 (4): 205-206.

  8. 玉村 啓和: 創薬を先導する中分子ペプチド 月刊「細胞」. 2023.07; 55 (9): 660-661.

  9. 岸田晶夫: 脱細胞化組織を用いた医療機器の研究開発における動物との関わり オベリスク. 2023.06; 28 (2): 16-22.

  10. 松元 亮: "ボロノレクチン"による生体対話を通じて切り拓くバイオエンジニアリング 薬学雑誌. 2023.05; 143 (5): 435-441. ( 医中誌 )

  11. 平田 悠, 野村 和弘, 加藤 大輔, 橘 吉寿, 内山 奏, 細岡 哲也, 原 雄二, 安達 貴弘, 柴崎 貢志, 和氣 弘明, 小川 渉: 不動化における筋量制御のメカニズム 日本臨床分子医学会学術総会プログラム・抄録集. 2023.04; 58回 56. ( 医中誌 )

  12. Kobayakawa Takuya, Yokoyama Masaru, Tsuji Kohei, Fujino Masayuki, Kurakami Masaki, Onishi Takato, Boku Sayaka, Ishii Takahiro, Miura Yutaro, Shinohara Kouki, Kishihara Yuki, Ohashi Nami, Kotani Osamu, Murakami Tsutomu, Sato Hironori, Tamamura Hirokazu: Low-molecular-weight anti-HIV-1 agents targeting HIV-1 capsid proteins RSC ADVANCES. 2023.01; 13 (3): 2156-2167. ( PubMed , DOI )

  13. Matsumoto Akira: "Borono-lectin"-mediated Crosstalk and Its Application to Bioengineering YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN. 2023; 143 (5): 435-441. ( PubMed , DOI )

  1. Fujisaki Hideki, Matsumoto Akira, Miyahara Yuji, Goda Tatsuro: Sialic acid biosensing by post-printing modification of PEDOT:PSS with pyridylboronic acid SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS. 2022.12; 23 (1): 525-534. ( PubMed , DOI )

  2. 細谷孝充: クリックケミストリーと生体直交化学の開発． 現代化学. 2022.12; 621 (12): 22-25.

  3. 三林浩二: 揮発性マーカーのバイオ光による非侵襲計測とイメージング 光学. 2022.11; 51 (11): 476-483.

  4. 飯谷 健太, 張 耿, 當麻 浩司, 荒川 貴博, 三林 浩二: 表面を機能化したバイオ蛍光デバイスによる皮膚ガス計測&イメージング 表面技術. 2022.09; 73 444-449.

  5. 荒川 貴博, 三林 浩二: 血液VOCs計測のためのヘッドホン型外耳ガスセンサ 電気学会誌. 2022.09; 142 (9): 564-567.

  6. 花園祐矢,平野優,玉田太郎,三木邦夫: 高分解能中性子構造から明らかになったタンパク質中のペプチド結合における新しい描像 日本結晶学会誌. 2022.08; 64 (3):

  7. 大石 由美子: 【マクロファージの多様性】筋再生におけるマクロファージの役割 臨床免疫・アレルギー科. 2022.08; 78 (2): 175-178. ( 医中誌 )

  8. 岸田晶夫: 高静水圧を用いた生物組織の脱細胞化と医療用材料への応用 油空圧技術. 2022.08; 61 (8): 18-25.

  9. 安達 貴弘: IgAと回腸炎 臨床免疫・アレルギー科. 2022.08; 78 (2): 206-211. ( 医中誌 )

  10. 飯谷健太, 鈴木美華, 當麻浩司, 荒川貴博, 三林浩二: バイオ蛍光式アセトンガス動画像化カメラのための酵素固定化メッシュの作製と評価 電気学会論文誌Ｅ（センサ・マイクロマシン部門誌）. 2022.07; 142 (7): 166-167. ( DOI )

  11. 吉本 由紀, 大石 由美子: 【基盤病態としての慢性炎症】筋疾患と慢性炎症 医学のあゆみ. 2022.07; 282 (1): 43-48. ( 医中誌 )

  12. Gentaro Kawase, Takumi Oishi, Kenta Iitani, Koji Toma, Takahiro Arakawa, Kohji Mitsubayashi: Mouthguard type biosensor for wireless measurement of salivary uric acid Journal of Advanced Science. 2022.06; 34 34301-1-34301-3. ( DOI )

  13. Abe Chizumi, Higuchi Ohki, Matsumoto Akira, Miyazawa Taiki: Determination of intracellular ascorbic acid using tandem mass spectrometry ANALYST. 2022.06; 147 (12): 2640-2643. ( PubMed , DOI )

  14. 小池 博之, 大石 由美子: 【栄養・代謝物シグナルと食品機能 転写、エピゲノムの制御から代謝性疾患の治療・予防に向けて】(第1章)食品の機能性と栄養・代謝物シグナル 骨格筋萎縮に対するビタミンA誘導体の機能評価 実験医学. 2022.05; 40 (7): 1027-1031. ( 医中誌 )

  15. 大石 由美子, 小池 博之: フレイル、サルコペニアのバイオマーカー 加齢による筋損傷後再生不全のメカニズム 日本老年医学会雑誌. 2022.05; 59 (Suppl.): 49. ( 医中誌 )

  16. 小早川 拓也, 辻 耕平, 玉村 啓和: 「ペプチドミメティックを活用した中分子型創薬リードの創製」 「月刊バイオインダストリー」特集“ペプチド医薬の最新動向～広い観点からのペプチド創薬科学～” 「監修 木曽 良明」. 2022.05; 39 (5): 69-84.

  17. 野村 渉, 玉村 啓和: 「HIV-1阻害剤・腫瘍認識プローブとしてのケモカイン受容体リガンド」 「月刊バイオインダストリー」特集“ペプチド医薬の最新動向～広い観点からのペプチド創薬科学～” 「監修 木曽 良明」. 2022.05; 39 (5): 15-25.

  18. 小池 博之, 大石 由美子: 【栄養・代謝物シグナルと食品機能　転写、エピゲノムの制御から代謝性疾患の治療・予防に向けて】(第1章)食品の機能性と栄養・代謝物シグナル　骨格筋萎縮に対するビタミンA誘導体の機能評価 実験医学. 2022.05; 40 (7): 1027-1031. ( 医中誌 )

  19. 丹羽　節，植竹裕太，細谷孝充: 塩基を添加しないクロスカップリングの開発 ―大型放射光施設を活用した反応機構の解析―． 化学. 2022.05; 77 (5): 12-16.

  20. 仁科 博史: 動物における臓器サイズ制御機構 再生医療. 2022.05; 21 (2): 74-79. ( 医中誌 )

  21. 平田 悠, 野村 和弘, 加藤 大輔, 橘 吉寿, 内山 奏, 細岡 哲也, 原 雄二, 安達 貴弘, 柴崎 貢志, 和氣 弘明, 小川 渉: 不動化はPiezo1/KLF15経路を介して筋萎縮を促進する 糖尿病. 2022.04; 65 (Suppl.1): S-185. ( 医中誌 )

  22. 平田 悠, 野村 和弘, 加藤 大輔, 橘 吉寿, 内山 奏, 細岡 哲也, 原 雄二, 安達 貴弘, 柴崎 貢志, 和氣 弘明, 小川 渉: 不動化はPiezo1/KLF15経路を介して筋萎縮を促進する 糖尿病. 2022.04; 65 (Suppl.1): S-185. ( 医中誌 )

  23. 大石 由美子: 【シン・マクロファージ　あらゆる疾患を制御する機能的多様性】(第1章)マクロファージの分化・活性化・制御を知る8つの方法　脂肪酸によるマクロファージ機能制御 実験医学. 2022.03; 40 (5): 650-654. ( 医中誌 )

  24. 飯谷 健太, 張 耿, 當麻 浩司, 荒川貴博, 三林 浩二: 呼気・皮膚ガスのバイオ蛍光センシングとイメージング 電子情報通信学会. 2022.03; 105 200-208.

  25. 安達 貴弘: 免疫グロブリンAによる小腸恒常性維持機能 バイオサイエンスとインダストリー. 2022.03; 80 (2): 142-143. ( 医中誌 )

  26. 平田 悠, 野村 和弘, 加藤 大輔, 橘 吉寿, 内山 奏, 細岡 哲也, 原 雄二, 安達 貴弘, 柴崎 貢志, 和氣 弘明, 小川 渉: 不動化はPiezo1/KLF15経路を介して筋萎縮を促進する 肥満研究. 2022.03; 27 (Suppl.): 328. ( 医中誌 )

  27. Kuleape Joshua Agbemefa, Hossain Shakhawoat, Sinclear Caleb Kwame, Shimizu Takanobu, Iwasa Hiroaki, Maruyama Junichi, Arimoto-Matsuzaki Kyoko, Nishina Hiroshi, Hata Yutaka: DNA Damage Triggers the Nuclear Accumulation of RASSF6 Tumor Suppressor Protein via CDK9 and BAF53 To Regulate p53 Target Gene Transcription MOLECULAR AND CELLULAR BIOLOGY. 2022.02; 42 (2):

  1. Yang Wenqian, Miyazaki Takuya, Chen Pengwen, Hong Taehun, Naito Mitsuru, Miyahara Yuji, Matsumoto Akira, Kataoka Kazunori, Miyata Kanjiro, Cabral Horacio: Block catiomer with flexible cationic segment enhances complexation with siRNA and the delivery performance in vitro SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS. 2021.12; 22 (1): 850-863. ( PubMed , DOI )

  2. Fujisaki Hideki, Watcharawittayakul Tongchatra, Matsumoto Akira, Miyahara Yuji, Goda Tatsuro: In-situ chemical modification of printed conducting polymer films for specific glucose biosensing SENSORS AND ACTUATORS B-CHEMICAL. 2021.12; 349 ( DOI )

  3. 辻 耕平: 医薬化学　SARS-CoV-2メインプロテアーゼ(Mpro)を標的とした阻害薬開発の動向 ファルマシア（日本薬学会 東京）. 2021.12; 57 (12): 1133. ( 医中誌 )

  4. Morishita Mayu, Arimoto-Matsuzaki Kyoko, Kitamura Masami, Niimura Kyohei, Iwasa Hiroaki, Maruyama Junichi, Hiraoka Yuichi, Yamamoto Kohei, Kitagawa Masanobu, Miyamura Norio, Nishina Hiroshi, Hata Yutaka: Characterization of mouse embryonic fibroblasts derived from Rassf6 knockout mice shows the implication of Rassf6 in the regulation of NF-kappa B signaling GENES TO CELLS. 2021.12; 26 (12): 999-1013. ( PubMed , DOI )

  5. 小池 博之, 大石 由美子: 生体恒常性および疾患を制御する間質細胞生物学 骨格筋幹細胞とマクロファージ亜集団の相互作用による組織修復制御 日本生化学会大会プログラム・講演要旨集. 2021.11; 94回 [2S04e-05]. ( 医中誌 )

  6. 大石 由美子, 小池 博之: 脂質生物学の新しいパラダイム マクロファージの「脂質」による再生・組織修復の制御 日本生化学会大会プログラム・講演要旨集. 2021.11; 94回 [2S01m-05]. ( 医中誌 )

  7. Numoto Nobutaka, Kawano Yoshiaki, Okumura Hideo, Baba Seiki, Fukumori Yoshihiro, Miki Kunio, Ito Nobutoshi: Coarse snapshots of oxygen-dissociation intermediates of a giant hemoglobin elucidated by determining the oxygen saturation in individual subunits in the crystalline state IUCRJ. 2021.11; 8 (Pt 6): 954-962. ( PubMed , DOI )

  8. 渡辺 藍子, 小池 博之, 大石 由美子: 骨髄球系細胞が持つ細胞内時計の錯乱が筋再生に及ぼす影響 日本筋学会学術集会プログラム・抄録集. 2021.11; 7回 116. ( 医中誌 )

  9. 細谷孝充: 異種アジド選択的反応 ファルマシア. 2021.11; 57 (11): 989-993. ( DOI )

  10. Igarashi Kazunori, Cabral Horacio, Hong Taehun, Anraku Yasutaka, Mpekris Fotios, Stylianopoulos Triantafyllos, Khan Thahomina, Matsumoto Akira, Kataoka Kazunori, Matsumoto Yu, Yamasoba Tatsuya: Vascular Bursts Act as a Versatile Tumor Vessel Permeation Route for Blood-Borne Particles and Cells SMALL. 2021.10; 17 (42): e2103751. ( PubMed , DOI )

  11. 松元 亮, 宮崎 拓也, 伊藤 美智子, 菅波 孝祥, 宮原 裕二: 【すべての人々の健康・福祉の実現に貢献するバイオマテリアル】ボロン酸ゲルを用いた糖尿病治療デバイスの社会実装 バイオマテリアル-生体材料-. 2021.10; 39 (4): 252-257. ( 医中誌 )

  12. 玉村 啓和: 明日の創薬を先導する中分子「ペプチド」 ファルマシア オピニオン（日本薬学会 東京）. 2021.09; 57 (9): 791.

  13. 吉田尚記, 増澤徹, 長真啓, 尾関和秀, 岸田晶夫, 築谷朋典, 水野敏秀, 西中知博, 巽英介: 補助人工心臓装置を支援する自己接合型脱血管の研究開発 ライフサポート. 2021.08; 33 (3): 102-107.

  14. Numoto N., Hirata K., Akatsu C., Tsubata T., Ito N.: Molecular mechanism of self-antigen recognition by the ligand binding domain of B cell inhibitory co-receptor CD72 ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES. 2021.08; 77 C526.

  15. 大石 由美子: 【マクロファージ研究の新展開】脂質によるマクロファージ機能制御 血液内科. 2021.07; 83 (1): 14-19. ( 医中誌 )

  16. 平田 悠, 野村 和弘, 加藤 大輔, 橘 吉寿, 内山 奏, 細岡 哲也, 和氣 弘明, 安達 貴弘, 小川 渉: 骨格筋生体イメージングを活用した不動化性筋萎縮の発症メカニズムの解析 糖尿病. 2021.05; 64 (Suppl.1): II-1. ( 医中誌 )

  17. 伊藤 美智子, 金井 紗綾香, 田村 篤志, 白川 伊吹, 金森 耀平, 田中 都, 松元 亮, 宮原 裕二, 小川 佳宏, 菅波 孝祥: マクロファージにおける脂質代謝障害に着目したNASH発症機構の解明 日本内分泌学会雑誌. 2021.04; 97 (1): 282. ( 医中誌 )

  18. 伊藤美智子、金井紗綾香、田村篤志、白川伊吹、金森耀平、田中都、松元亮、宮原裕二、小川佳宏、菅波孝祥: マクロファージにおける脂質代謝障害に着目したNASH発症機構の解明 日本内分泌学会雑誌. 2021.04; 97 (1): 282.

  19. Jiang Xinliang, Maruyama Junichi, Iwasa Hiroaki, Arimoto-Matsuzaki Kyoko, Nishina Hiroshi, Hata Yutaka: Heat shock induces the nuclear accumulation of YAP1 via SRC (vol 399, 112439, 2021) EXPERIMENTAL CELL RESEARCH. 2021.04; 401 (2): 112555. ( PubMed , DOI )

  20. Kamimura Kenya, Yokoo Takeshi, Abe Hiroyuki, Ohtsuka Masato, Miura Hiromi, Nishina Hiroshi, Terai Shuji: Development of Hydrodynamics-Based Gene Therapy for Liver Cancer MOLECULAR THERAPY. 2021.04; 29 (4): 55-56.

  21. 棚谷 綾, 吉岡 千咲, 増野 弘幸, 森 修一, 伊藤 暢聡, 影近 弘之, 平田 尚也, 諫田 泰成: リトコール酸をリードとしたビタミンD誘導体の構造展開 ビタミン. 2021.03; 95 (3): 100-101. ( 医中誌 )

  22. 安達 貴弘: 【ニューノーマル時代の免疫・アレルギー関連素材を探る】プロポリスの免疫系への作用 機能性食品と薬理栄養. 2021.02; 14 (4): 230-236. ( 医中誌 )

  23. 小池 博之, 大石 由美子: 【糖尿病治療・研究の最前線2021】基礎研究　骨格筋組織再生を対象としたシングルセルRNA-seq解析 医学のあゆみ. 2021.01; 276 (5): 443-447. ( 医中誌 )

  1. 大石 由美子: 炎症と再生を協調して制御する分子メカニズムの解明 上原記念生命科学財団研究報告集. 2020.12; 34 1-4. ( 医中誌 )

  2. Arakawa T, Iitani K, Toma K, Mitsubayashi K: 非侵襲診断を目指した生化学式ガスセンサと可視化計測システムに関するレビュー 電気学会論文誌E. 2020.11; 140 (11): 321-327. ( DOI )

  3. 三林浩二: バイオ光技術による超高感度な生体ガス計測と動画像化 応用物理. 2020.11; 89 (11): 638-643.

  4. 河鰭公祥, Narintadeach Charoensombut, 金定賢, 木村剛, 岸田晶夫, 牛田多加志, 古川克子: 子宮組織由来脱細胞化マトリクスハイドロゲルの作製 臨床バイオメカニクス. 2020.10; 41 287-291.

  5. 松元 亮: 非機械型で完全合成型「貼るだけ人工膵臓」開発の最前線 人工臓器. 2020.10; 49 (2): S-31. ( 医中誌 )

  6. 大石 由美子: 【免疫リプログラミングと細胞デザイン】免疫代謝リプログラミング　マクロファージの代謝リプログラミング 医学のあゆみ. 2020.10; 275 (1): 49-53. ( 医中誌 )

  7. 大石 由美子, 小池 博之: シングルセル解析で読み解く間質細胞の多様性 シングルセルトランスクリプトーム解析でみた骨格筋マクロファージの多様性 日本生化学会大会プログラム・講演要旨集. 2020.09; 93回 [2S04e-04]. ( 医中誌 )

  8. 小池 博之, 大石 由美子: シングルセルトランスクリプトーム解析からみた骨格筋再生における細胞間相互作用の変化 日本抗加齢医学会総会プログラム・抄録集. 2020.09; 20回 220. ( 医中誌 )

  9. 大石 由美子, 真鍋 一郎: 【肥満-外科治療と基礎研究の最新情報】他臓器との関連 マクロファージによる臓器間ネットワークの形成 医学のあゆみ. 2020.09; 274 (10): 1053-1057. ( 医中誌 )

  10. 大石 由美子, 真鍋 一郎: 【肥満-外科治療と基礎研究の最新情報】他臓器との関連　マクロファージによる臓器間ネットワークの形成 医学のあゆみ. 2020.09; 274 (10): 1053-1057. ( 医中誌 )

  11. 木村 真一郎, 桑田 博仁, 田中 都, 松本 裕子, 越智 梢, 岡田 純, 渡辺 亜希子, 白川 伊吹, 馬場 利明, 吉田 博, 宮原 裕二, 石井 均, 小川 佳宏, 松元 亮, 菅波 孝祥: スマートインスリンデバイスによる新たな糖尿病治療戦略の検討 糖尿病. 2020.08; 63 (Suppl.1): S-123. ( 医中誌 )

  12. 木村 真一郎, 桑田 博仁, 田中 都, 松本 裕子, 越智 梢, 渡辺 亜希子, 岡田 純, 白川 伊吹, 馬場 利明, 吉田 博, 宮原 裕二, 石井 均, 小川 佳宏, 松元 亮, 菅波 孝祥: スマートインスリンデバイスによる革新的な糖尿病治療戦略の開発 日本内分泌学会雑誌. 2020.08; 96 (1): 231. ( 医中誌 )

  13. 宮崎 大輔, 松井 誠, Chen Siyuan, 宮崎 拓也, 武元 宏泰, 野本 貴大, 松元 亮, 三浦 裕, 西山 伸宏: ナノメディシンの低侵襲的な投与に向けた多孔性シルクマイクロニードルの創製 日本DDS学会学術集会プログラム予稿集. 2020.08; 36回 140. ( 医中誌 )

  14. 三林 浩二: 非侵襲診断および健康モニタリングのための気相バイオ計測 エレクトロニクス実装学会誌. 2020.08; 23 (5): 337-341.

  15. 大石 由美子, 真鍋 一郎: 【腎臓と他臓器連関を考える-CKDにおける包括的治療戦略を目指して】免疫応答による臓器連関 内科. 2020.08; 126 (2): 175-180. ( 医中誌 )

  16. 大石 由美子, 真鍋 一郎: 【腎臓と他臓器連関を考える-CKDにおける包括的治療戦略を目指して】免疫応答による臓器連関 内科. 2020.08; 126 (2): 175-180. ( 医中誌 )

  17. 仁科 博史: 【細胞競合による生体制御とがん】細胞競合とがん　Hippo-YAPシグナル経路を介した異常細胞の排除 医学のあゆみ. 2020.08; 274 (5): 451-455. ( 医中誌 )

  18. 玉村 啓和, 小早川 拓也, 辻 耕平: 環状ペプチドで標的細胞へターゲティングする 「Drug Delivery System」特集“中分子創薬とDDS”. 2020.07; 35 (3): 170-180.

  19. 大石 由美子, 真鍋 一郎: 【あたらしい臓器連関】臓器間ネットワークによる心臓恒常性維持と心不全 細胞. 2020.06; 52 (7): 369-371. ( 医中誌 )

  20. 安達 貴弘: 【食と健康を結ぶメディカルサイエンス 生体防御系を亢進し、健康の維持に働く分子機構】(第4章)食と健康研究のための最先端技術 生体イメージングによる食シグナルおよび未病・病態の解析 実験医学. 2020.06; 38 (10): 1779-1786. ( 医中誌 )

  21. 松元 亮: 「"貼るだけ"人工膵臓」開発の最前線 日本栄養・食糧学会大会講演要旨集. 2020.04; 74回 130. ( 医中誌 )

  22. 菅波 孝祥, 田中 都, 木村 真一郎, 桑田 博仁, 越智 梢, 渡辺 亜希子, 松元 亮, Chen Siyuan, 松本 裕子, 宮崎 拓也, 伊藤 美智子, 宮原 裕二: 次世代型の人工膵臓による革新的な糖尿病治療機器の開発 生体医歯工学共同研究拠点成果報告書. 2020.04; 令和元年度 128. ( 医中誌 )

  23. 田畑 美幸, 合田 達郎, 松元 亮, 宮原 裕二, 吉岡 祐亮, 落谷 孝宏: 低分子核酸を定量解析するpHセンサチップの開発 生体医歯工学共同研究拠点成果報告書. 2020.04; 令和元年度 161. ( 医中誌 )

  24. 向田 彩乃, 宮澤 大樹, 松元 亮, 宮原 裕二: 抗がん作用に及ぼすビタミンC酸化体の存在意義の解明 日本栄養・食糧学会大会講演要旨集. 2020.04; 74回 257. ( 医中誌 )

  25. 大石 由美子: 【いま、脂質がおもしろい～若手研究者による最新の脂質研究～】基礎　脂肪酸によるマクロファージ機能制御と生活習慣病 The Lipid. 2020.04; 31 (1): 59-64. ( 医中誌 )

  26. 吉原 綾菜, 吉岡 千咲, 川崎 波留, 増野 弘幸, 河内 恵美子, 諫田 泰成, 平田 尚也, 伊藤 暢聡, 影近 弘之, 棚谷 綾: 高いビタミンD活性を有するリトコール酸側鎖誘導体の創製 ビタミン. 2020.04; 94 (4): 287. ( 医中誌 )

  27. 大石 由美子, 真鍋 一郎: 【臓器連関-腎臓を中心に】心腎連関 AKIにおける心障害 腎臓内科. 2020.04; 11 (4): 360-363. ( 医中誌 )

  28. 大石 由美子, 真鍋 一郎: 【臓器連関-腎臓を中心に】心腎連関 AKIにおける心障害 腎臓内科. 2020.04; 11 (4): 360-363. ( 医中誌 )

  29. 大石 由美子, 真鍋 一郎: 【臓器連関-腎臓を中心に】心腎連関　AKIにおける心障害 腎臓内科. 2020.04; 11 (4): 360-363. ( 医中誌 )

  30. 山下暁立, 舩本誠一, 張永巍, 橋本良秀, 岸田晶夫: 小口径グラフトとしての生体由来脱細胞化血管の有用性 日本心臓外科学会誌. 2020.03; 49 (2): 45-51. ( DOI )

  31. Takahiro Arakawa, Takashi Aota, Koji Toma, Kohji Mitsubayash: 生化学式ガスセンサとガス濃縮装置を用いた経皮エタノールガス計測システム 電気学会論文誌E. 2020.03; 140 182-185. ( DOI )

  32. Shota Suzuki, Masato Tsujii, Koji Toma, Takahiro Arakawa, Kohji Mitsubayash: 呼気中アセトン・イソプロパノールの間欠繰り返し計測のためのバイオスニファに関する研究 電気学会論文誌E. 2020.03; 140 177-181. ( DOI )

  33. 中村奈緒子, 木村剛, 山田将博, 岸田晶夫: 細胞外マトリックスと人工歯根による歯根膜再構築 バイオマテリアル-生体材料-. 2020.01; 38 (1): 26-27. ( 医中誌 )

  1. 三林 浩二: 呼気や皮膚ガスのためのバイオ蛍光式ガスセンサおよび可視化システム OPTRONICS. 2019.12; 38 (456): 77-81.

  2. 木村 真一郎, 田中 都, 松元 亮, 菅波 孝祥: 人工膵臓様デバイスによる血糖管理の未来 Pharma Medica. 2019.12; 37 (12): 59-62.

  3. 羽根田洋輔, 増澤　徹, 長　真啓, 尾関和秀, 岸田晶夫, 巽英介: 冠動脈バイパス手術における欠陥接合支援デバイスの研究開発 ライフサポート. 2019.12; 31 (4): 151-157.

  4. 岸田晶夫: 組織工学と再生医療2019 人工臓器. 2019.12; 48 (3): 199-204.

  5. 大石 由美子, 真鍋 一郎: 【サイトカインのすべて】生命現象とサイトカイン　病態との関連　心血管代謝疾患とサイトカイン 医学のあゆみ. 2019.11; 271 (5): 559-563. ( 医中誌 )

  6. 大石 由美子, 真鍋 一郎: 【サイトカインのすべて】生命現象とサイトカイン 病態との関連 心血管代謝疾患とサイトカイン 医学のあゆみ. 2019.11; 271 (5): 559-563. ( 医中誌 )

  7. 松田 幸樹, 服部 真一朗, 土屋 亮人, 小早川 拓也, 潟永 博之, 吉村 和久, 岡 慎一, 遠藤 泰之, 玉村 啓和, 満屋 裕明, 前田 賢次: HIV再活性化に伴うアポトーシス誘導能を用いたHIVリザーバー除去に資する新たなShock&Kill療法の可能性 日本エイズ学会誌. 2019.11; 21 (4): 474. ( 医中誌 )

  8. 村上 努, 海老原 健人, 小早川 拓也, 藤野 真之, 児玉 栄一, 玉村 啓和: 二量体化HIV-1膜融合阻害剤の作用機構 日本エイズ学会誌. 2019.11; 21 (4): 427. ( 医中誌 )

  9. 波多野 豊晃, 合田 達郎, 松元 亮, 宮原 裕二: 上皮タイトジャンクション形成の新規評価手法の開発 日本バイオマテリアル学会大会予稿集. 2019.11; 41回 160. ( 医中誌 )

  10. 合田 達郎, 波多野 豊晃, 松元 亮, 石原 一彦, 宮原 裕二: 両親媒性リン脂質ポリマーの上皮細胞バリア透過挙動の解明 日本バイオマテリアル学会大会予稿集. 2019.11; 41回 154. ( 医中誌 )

  11. 宮島 健, 内藤 瑞, 松元 亮, 宮原 裕二, 宮田 完二郎: ピリジルボロン酸とがん細胞表面のシアル酸の特異的な結合を利用したポリマー型リガンドの開発 日本バイオマテリアル学会大会予稿集. 2019.11; 41回 488. ( 医中誌 )

  12. 三林 浩二: 生体ガスの非侵襲バイオセンシング　ー気相用バイオセンサーと探嗅カメラー ぶんせき. 2019.10; (10): 462-465.

  13. 小早川拓也, 玉村啓和: ペプチドミメティック 有機合成化学協会誌 十字路. 2019.09; 77 (9): 923.

  14. 小早川拓也, 玉村啓和: クロロアルケン骨格を基盤としたペプチドミメティック化学への展開 有機合成化学協会誌 総合論文. 2019.09; 77 (9): 904-911.

  15. 丹羽　節, 細谷孝充: 芳香族フッ化物の脱フッ素ホウ素化反応 有機合成化学協会誌. 2019.09; 77 (9): 883-894.

  16. 林 晋一郎, 真鍋 一郎, 西野 一三, 大石 由美子: 代謝による炎症・再生コンティニアムの制御と破綻 骨格筋の再生・発生過程における筋細胞の分化制御メカニズム 日本生化学会大会プログラム・講演要旨集. 2019.09; 92回 [1S02a-05]. ( 医中誌 )

  17. 岸田晶夫: 循環器外科・内科 特殊鋼. 2019.09; 68 (5): 53-55.

  18. 棚谷 綾, 吉岡 千咲, 川崎 波留, 佐々木 晴江, 藤原 葉子, 増野 弘幸, 伊藤 暢聡, 影近 弘之: ビタミンD活性を有するリトコール酸誘導体の構造展開 ビタミン. 2019.08; 93 (8): 370-371. ( 医中誌 )

  19. 小早川拓也: オキセタニル骨格を活用したペプチドミメティック化学への展開 有機合成化学協会誌 Review de Debut. 2019.07; 77 (7): 720-721.

  20. 革新的な糖尿病治療ー機械も注射も使わない人工膵臓の開発ー キャノン財団 第10回助成先だより. 2019.07;

  21. 岸田晶夫: 細胞外マトリックスによる組織・臓器再建 現代化学. 2019.06; 2019 (6): 60-62.

  22. 大石 由美子: 【老化と炎症】代謝と炎症 アンチ・エイジング医学. 2019.06; 15 (3): 330-333. ( 医中誌 )

  23. 松元 亮, 宮原 裕二: 【レクチン医学最前線】糖鎖を標的とした工学的アプローチ ボロノレクチンを利用したバイオエンジニアリング 医学のあゆみ. 2019.06; 269 (9): 697-702.

  24. 「ボロノレクチン」工学が拓く新しい治療オプション MDB技術予測レポート‐2050年　未来・世界を変える技術‐. 2019.05;

  25. 松元 亮: "エレクトロニクスフリー"で完全合成型の人工膵臓の開発 バイオサイエンスとインダストリー. 2019.05; 77 (3): 256-257.

  26. 宮島 健, 内藤 瑞, 宮田 完二郎, 松元 亮, 宮原 裕二: がん細胞表面のシアル酸を特異的に認識するボロン酸含有ポリマー型リガンドの開発 生体医歯工学共同研究拠点成果報告書. 2019.04; 平成30年度 63. ( 医中誌 )

  27. 田畑 美幸, 合田 達郎, 松元 亮, 宮原 裕二, 加藤 功一: 核酸増幅モニタリングを目指した薄膜電気化学センサ 生体医歯工学共同研究拠点成果報告書. 2019.04; 平成30年度 126. ( 医中誌 )

  28. 田畑 美幸, 合田 達郎, 松元 亮, 宮原 裕二, Tenaglia Enrico, Guiducci Carlotta: 等温核酸増幅法を利用したラベルフリーな電気化学的DNA検出法の確立 生体医歯工学共同研究拠点成果報告書. 2019.04; 平成30年度 125. ( 医中誌 )

  29. 菅波 孝祥, 田中 都, 木村 真一郎, 桑田 博仁, 越智 梢, 渡辺 亜希子, 松元 亮, 松本 裕子, 宮原 裕二: スマートインスリンデバイスによる革新的な糖尿病治療機器の開発 生体医歯工学共同研究拠点成果報告書. 2019.04; 平成30年度 57. ( 医中誌 )

  30. 田畑 美幸, 合田 達郎, 松元 亮, 宮原 裕二, 吉岡 祐亮, 落谷 孝弘: リキッドバイオプシー応用のためのラベルフリーにmicroRNAを検出する電気化学センサ 生体医歯工学共同研究拠点成果報告書. 2019.04; 平成30年度 127. ( 医中誌 )

  31. 木村 真一郎, 桑田 博仁, 田中 都, 越智 梢, 松本 裕子, 岡田 純, 渡辺 亜希子, 白川 伊吹, 馬場 利明, 吉田 博, 宮原 裕二, 石井 均, 小川 佳宏, 松元 亮, 菅波 孝祥: 中空糸融合型人工膵臓デバイスによる新たな糖尿病治療戦略の開発 日本内分泌学会雑誌. 2019.04; 95 (1): 374. ( 医中誌 )

  32. 菅波 孝祥, 田中 都, 木村 真一郎, 桑田 博仁, 越智 梢, 渡辺 亜希子, 松元 亮, 松本 裕子, 宮原 裕二: スマートインスリンデバイスによる革新的な糖尿病治療機器の開発 生体医歯工学共同研究拠点成果報告書. 2019.04; 平成30年度 57.

  33. 木村 真一郎, 桑田 博仁, 田中 都, 松本 裕子, 越智 梢, 馬場 利明, 吉田 博, 宮原 裕二, 石井 均, 小川 佳宏, 松元 亮, 菅波 孝祥: 中空糸融合型人工膵臓デバイスによる新たな糖尿病治療戦略の開発 日本臨床分子医学会学術総会プログラム・抄録集. 2019.04; 56回 73.

  34. 田畑 美幸, 合田 達郎, 松元 亮, 宮原 裕二, Tenaglia Enrico, Guiducci Carlotta: 等温核酸増幅法を利用したラベルフリーな電気化学的DNA検出法の確立 生体医歯工学共同研究拠点成果報告書. 2019.04; 平成30年度 125.

  35. 田畑 美幸, 合田 達郎, 松元 亮, 宮原 裕二, 加藤 功一: 核酸増幅モニタリングを目指した薄膜電気化学センサ 生体医歯工学共同研究拠点成果報告書. 2019.04; 平成30年度 126.

  36. 田畑 美幸, 合田 達郎, 松元 亮, 宮原 裕二, 加藤 功一: 核酸増幅モニタリングを目指した薄膜電気化学センサ 生体医歯工学共同研究拠点成果報告書. 2019.04; 平成30年度 126.

  37. 三林浩二: バイオセンサ技術を用いた非侵襲生体計測 化学工学. 2019.03; 83 (3): 171-174.

  38. 内田圭祐, 吉田　優, 細谷孝充: 多成分集積を指向した合成のためのアライン化学 有機合成化学協会誌. 2019.02; 77 (2): 145-162.

  1. 大石 由美子: 【免疫と代謝(イムノメタボリズム)】炎症応答の収束とマクロファージにおける脂肪酸の代謝 炎症と免疫. 2018.12; 27 (1): 30-34. ( 医中誌 )

  2. 宮村 憲央, 仁科 博史: Hippo-YAPシグナル伝達経路による異常細胞の排除 生化学. 2018.12; 90 (6): 804-809. ( 医中誌 )

  3. 三林浩二: 近未来医療を見据えたキャビタス（窩腔）バイオセンサ グリーンテクノロジー. 2018.10; (10): 29-33.

  4. 三林浩二: 近未来医療を見据えたキャビタス（窩腔）バイオセンサ グリーンテクノロジー. 2018.10; (10): 29-33.

  5. 大石 由美子: 【脂肪の量と質を制御する　脂肪毒性の新たなメカニズムを理解してメタボ克服に挑む】細胞内脂質代謝による慢性炎症の制御 実験医学. 2018.10; 36 (16): 2727-2731. ( 医中誌 )

  6. 細江 雄飛, 稲葉 理美, 沼本 修孝, 伊藤 暢聡, 織田 昌幸: SH2ドメインスワップダイマーが与える安定性と機能への影響評価 日本生化学会大会プログラム・講演要旨集. 2018.09; 91回 [1T11e-04(1P. ( 医中誌 )

  7. 沼本 修孝, 赤津 ちづる, 品川 健朗, 鍔田 武志, 伊藤 暢聡: B細胞抑制性因子CD72とSm/RNPの複合体形成様式の推測 日本生化学会大会プログラム・講演要旨集. 2018.09; 91回 [1P-084]. ( 医中誌 )

  8. 板倉 正典, 佐々木 栄太, 安達 貴弘, 内田 浩二: デヒドロアスコルビン酸修飾による血清アルブミンの自然免疫活性化機能の獲得 日本生化学会大会プログラム・講演要旨集. 2018.09; 91回 [3P-340].

  9. 山下暁立、舩本誠一、張永巍、橋本良秀、岸田晶夫: 開心術後の癒着防止材料の評価を目的とした心膜癒着動物モデルの構築および製品評価 胸部外科. 2018.09; 71 (9): 658-663.

  10. 板倉 正典, 佐々木 栄太, 安達 貴弘, 内田 浩二: デヒドロアスコルビン酸修飾による血清アルブミンの自然免疫活性化機能の獲得 日本生化学会大会プログラム・講演要旨集. 2018.09; 91回 [3P-340]. ( 医中誌 )

  11. 佐藤憲子: Developmental Origin of Health and Disease (DOHaD)を理解する新時代の到来 ゲノム・エピゲノムと加齢性慢性疾患の関連性に関する新たな視点 化学と生物. 2018.09; 55 (9): 613-620. ( 医中誌 )

  12. 桑田 博仁, 田中 都, 越智 梢, 松本 裕子, 白川 伊吹, 宮原 裕二, 石井 均, 小川 佳宏, 松元 亮, 菅波 孝祥: グルコース応答性ゲルを用いた人工膵臓様デバイスによる新規糖尿病治療戦略の開発 肥満研究. 2018.09; 24 (Suppl.): 166.

  13. 林 晋一郎, 大石 由美子, 真鍋 一郎, 西野 一三: Klf5による骨格筋発生の制御機構 日本筋学会学術集会プログラム・抄録集. 2018.08; 4回 124. ( 医中誌 )

  14. 堀口 諭吉, 合田 達郎, 松元 亮, 武内 寛明, 山岡 昇司, 宮原 裕二: 細孔電気抵抗法を用いたヒトインフルエンザウイルスの特異的検出 日本分析化学会講演要旨集. 2018.08; 67年会 87. ( 医中誌 )

  15. 丹羽　節, 細谷孝充: 分子をつくり変える ―PETイメージングへの応用に向けて― 現代化学. 2018.07; 568 (7): 42-46.

  16. 三林浩二: バイオ蛍光式「バイオスニファ」「探嗅カメラ」による高感度な生体ガス計測と可視化応用 電気化学. 2018.06; 86 (Summer): 118-122.

  17. 岸田晶夫: 材料開発を専門としない研究者のための最新の生体材料事情 人工臓器. 2018.06; 47 (1): 18-20.

  18. 大石 由美子, 真鍋 一郎: 【自然免疫の最前線】自然免疫系による疾患の誘導と制御　脂質代謝と老化にかかわる自然免疫シグナル 医学のあゆみ. 2018.06; 265 (13): 1276-1279. ( 医中誌 )

  19. 荒川貴博, 三林浩二: 研究室紹介「東京医科歯科大学生体材料工学研究所　センサ医工学分野　三林研究室」 クリーンテクノロジー. 2018.05; 28 (5): 70-73.

  20. Ainiwaer Dilinaer, 田畑 美幸, 合田 達郎, 松元 亮, 宮原 裕二, Tenaglia Enrico, Guiducci Carlotta: 等温核酸増幅法と組み合わせたpH-based microRNA検出システムの創製 生体医歯工学共同研究拠点成果報告書. 2018.04; 平成29年度 71. ( 医中誌 )

  21. 増山 絢子, 青柳 隆夫, 合田 達郎, 松元 亮, 宮原 裕二: 微小電極とイメージングによる単一細胞内外カルシウムイオン同時測定 生体医歯工学共同研究拠点成果報告書. 2018.04; 平成29年度 168. ( 医中誌 )

  22. 淡路 啓一郎, 星 徹, 青柳 隆夫, 飯塚 大介, 合田 達郎, 松元 亮, 宮原 裕二: 二リン酸検出を目的としたボロン酸ポリマーの合成と評価 生体医歯工学共同研究拠点成果報告書. 2018.04; 平成29年度 137. ( 医中誌 )

  23. 田畑 美幸, 合田 達郎, 松元 亮, 宮原 裕二, 吉岡 祐亮, 落谷 孝広: パターン化Ir/IrOxセンサの作製とリキッドバイオプシーへの応用 生体医歯工学共同研究拠点成果報告書. 2018.04; 平成29年度 166. ( 医中誌 )

  24. 内藤 瑞, 吉永 直人, 石井 武彦, 宮田 完二郎, 松元 亮, 宮原 裕二, 片岡 一則: ATP応答性高分子ミセルによる細胞質内へのsiRNA送達技術の開発 生体医歯工学共同研究拠点成果報告書. 2018.04; 平成29年度 52. ( 医中誌 )

  25. 安達 貴弘: 生体イメージングによる食シグナルおよび超早期未病の可視化解析 生体内のCa2+シグナルを見る 化学と生物. 2018.04; 56 (5): 345-352. ( 医中誌 )

  26. 安達貴弘: 生体イメージングによる食シグナルおよび超早期未病の可視化解析 生体内のCa2+シグナルを見る 化学と生物. 2018.04; 56 (5): 345‐352.

  27. 安達　貴弘: 生体イメージングによる食シグナルおよび超早期未病の可視化解析　生体内のCa2+シグナルを見る. 化学と生物. 2018.04; 56 (5): 345-352 .

  28. 菅波 孝祥, 田中 都, 越智 梢, 桑田 博仁, 岡田 純, 松元 亮, 松本 裕子, 宮原 裕二: スマートインスリンデバイスによる革新的な糖尿病治療機器の開発 生体医歯工学共同研究拠点成果報告書. 2018.04; 平成29年度 161.

  29. 内藤 瑞, 吉永 直人, 石井 武彦, 宮田 完二郎, 松元 亮, 宮原 裕二, 片岡 一則: ATP応答性高分子ミセルによる細胞質内へのsiRNA送達技術の開発 生体医歯工学共同研究拠点成果報告書. 2018.04; 平成29年度 52.

  30. 渡部 太郎, 永石 宇司, 細谷 明徳, Jose Nisha, 津川 直也, 小島 裕大, 安達 貴弘, 渡辺 守: intra-vital imagingによる実験腸炎モデルにおける回盲部免疫応答の解析 日本消化器病学会雑誌. 2018.04; 115 (臨増総会): A335. ( 医中誌 )

  31. 石澤 通康, Otero Rocio, 沼本 修孝, 伊倉 貞吉, 伊藤 暢聡, 常盤 広明, Mourino Antonio, 槇島 誠, 山田 幸子: 25-Adamantyl-1α、25-dihydroxyvitamin D3誘導体の組織選択的活性 ビタミン. 2018.04; 92 (4): 232. ( 医中誌 )

  32. 桑田 博仁, 田中 都, 越智 梢, 松本 裕子, 後藤 沙也香, 白川 伊吹, 宮原 裕二, 石井 均, 小川 佳宏, 松元 亮, 菅波 孝祥: エレクトロニクスフリーな人工膵臓様デバイスによる新規糖尿病治療戦略の開発 糖尿病. 2018.04; 61 (Suppl.1): S-134.

  33. 田中 都, 桑田 博仁, 越智 梢, 松本 裕子, 後藤 沙也香, 白川 伊吹, 宮原 裕二, 石井 均, 小川 佳宏, 松元 亮, 菅波 孝祥: グルコース応答性スマートゲルを用いた新規インスリンデバイスの開発 日本内分泌学会雑誌. 2018.04; 94 (1): 324.

  34. Sato Atsushi, Shibuya Hiroshi: Glycogen synthase kinase 3 beta functions as a positive effector in the WNK signaling pathway PLOS ONE. 2018.03; 13 (3): e0193204. ( PubMed , DOI )

  35. 安達貴弘: 生体イメージングによる食シグナルの可視化解析 日本農芸化学会大会講演要旨集(Web). 2018.03; 2018 ROMBUNNO.4SY09‐1 (WEB ONLY).

  36. 渡部 太郎, 永石 宇司, 細谷 明徳, Jose Nisha, 津川 直也, 小島 裕大, 安達 貴弘, 渡辺 守: intra-vital imagingによる実験腸炎モデルにおける回盲部免疫応答の解析 日本消化器病学会雑誌. 2018.03; 115 (臨増総会): A335. ( 医中誌 )

  37. 大石 由美子, 真鍋 一郎: 【脂肪酸クオリティの多様性と病態】脂肪酸代謝制御によるマクロファージ機能制御 医学のあゆみ. 2018.03; 264 (11): 949-952. ( 医中誌 )

  38. 木村剛, 中村奈緒子, 橋本良秀, 坂口志文, 木村俊作, 岸田晶夫: 解離型分子を介した抗体固定化グラフト表面を用いた選択的な細胞捕獲・回収による細胞分離 高分子論文集. 2018.03; 75 (2): 155-163.

  39. 中村奈緒子, 木村剛, 岸田晶夫: 高分子複合化脱細胞化生体組織の医用応用 高分子論文集. 2018.03; 75 (2): 128-136.

  40. Inoue Ryosuke, Kamimura Kenya, Nagoya Takuro, Sakai Norihiro, Yokoo Takeshi, Goto Ryo, Ogawa Kohei, Shinagawa-Kobayashi Yoko, Watanabe-Mori Yukari, Sakamaki Akira, Abe Satoshi, Kamimura Hiroteru, Miyamura Norio, Nishina Hiroshi, Terai Shuji: Effect of a neural relay on liver regeneration in mice: activation of serotonin release from the gastrointestinal tract FEBS OPEN BIO. 2018.03; 8 (3): 449-460. ( PubMed , DOI )

  41. 津川 直也, 永石 宇司, 渡部 太郎, 細谷 明徳, Nisha Jose, 小島 裕大, 安達 貴弘, 渡辺 守: IgAによる腸内細菌叢制御と腸管粘膜防御の検証 日本消化管学会雑誌. 2018.02; 2 (Suppl.): 265. ( 医中誌 )

  42. 大石 由美子, 真鍋 一郎: 【血管の炎症を俯瞰する】血管の炎症　新しいビューポイント　動脈硬化と慢性炎症 診断と治療. 2018.02; 106 (2): 153-159. ( 医中誌 )

  43. 大石 由美子, 真鍋 一郎: 【高齢者における代謝栄養管理】Inflammaging 外科と代謝・栄養. 2018.02; 52 (1): 5-10. ( 医中誌 )

  44. Shinagawa-Kobayashi Yoko, Kamimura Kenya, Goto Ryo, Ogawa Kohei, Inoue Ryosuke, Yokoo Takeshi, Sakai Norihiro, Nagoya Takuro, Sakamaki Akira, Abe Satoshi, Sugitani Soichi, Yanagi Masahiko, Fujisawa Koichi, Nozawa Yoshizu, Koyama Naoto, Nishina Hiroshi, Furutani-Seiki Makoto, Sakaida Isao, Terai Shuji: Effect of histidine on sorafenib-induced vascular damage: Analysis using novel medaka fish model BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2018.02; 496 (2): 556-561. ( PubMed , DOI )

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  46. Miyamura Norio, Nishina Hiroshi: YAP regulates liver size and function CELL CYCLE. 2018; 17 (3): 267-268. ( PubMed , DOI )

  1. 清水 幹容, 田中 信之: ケモカインIL-8による糖代謝の制御機構とがん幹細胞への影響 生命科学系学会合同年次大会. 2017.12; 2017年度 [1P-1045]. ( 医中誌 )

  2. 大石　由美子: 脂肪酸代謝制御による炎症反応の収束 生化学. 2017.12; 89 (6): 907-910.

  3. 岡本 好海[内田], Yu Ruoxing, 仁科 博史: 【日本のイノベーションのアクセラレーター】ES細胞分化系を用いた簡便・高解像度な初期胚発生に対する医薬品リスク評価 ファルマシア. 2017.12; 53 (12): 1182-1186. ( 医中誌 )

  4. 佐藤 憲子: 疾患発症前段階の肝臓トランスクリプトーム・メタボローム解析　妊娠前期低タンパク質飼料給餌DOHaD動物実験 Medical Science Digest. 2017.12; 43 (12): 637-638. ( 医中誌 )

  5. 仁科 博史: 細胞張力可視化プローブを用いた3D組織構築機構の解明 上原記念生命科学財団研究報告集. 2017.12; 31 1-5. ( 医中誌 )

  6. 林 晋一郎, 真鍋 一郎, 西野 一三, 大石 由美子: 骨格筋細胞の新規老化メカニズム解析 生命科学系学会合同年次大会. 2017.12; 2017年度 [1P-0428]. ( 医中誌 )

  7. 大石 由美子: 脂肪酸代謝制御による炎症反応の収束 生化学. 2017.12; 89 (6): 907-910. ( 医中誌 )

  8. 松田 幸樹, 服部 真一朗, 土屋 亮人, 小早川 拓也, 大橋 南美, 野村 渉, 原田 恵嘉, 佐藤 賢文, 吉村 和久, 玉村 啓和, 満屋 裕明, 前田 賢次: HIV潜伏感染細胞を標的とした新規治療薬開発に有効なin vitro評価系の開発 日本エイズ学会誌. 2017.11; 19 (4): 403. ( 医中誌 )

  9. 合田 達郎, 波多野 豊晃, 松元 亮, 宮原 裕二: NH4Cl刺激による上皮細胞シート基底部の過渡的pH変化を指標とした密着結合の評価 日本バイオマテリアル学会大会予稿集. 2017.11; 39回 198. ( 医中誌 )

  10. 合田 達郎, 海 文峰, 堀口 諭吉, 松元 亮, 宮原 裕二: シアル酸糖鎖修飾型導電性高分子の創製とインフルエンザウイルスの電気的検出 日本バイオマテリアル学会大会予稿集. 2017.11; 39回 192. ( 医中誌 )

  11. 大石　由美子: 体内時計・加齢・摂取カロリーの深い関係 実験医学. 2017.11; 35 3104-3105.

  12. 原田 恵嘉, 野村 渉, 鳴海 哲夫, 横山 勝, 前田 賢次, 林 宏典, 紺野 奇重, 引地 優太, 佐藤 裕徳, 玉村 啓和, 俣野 哲朗, 吉村 和久: 網羅的Env標的阻害剤ライブラリーの構築(2) 日本エイズ学会誌. 2017.11; 19 (4): 401. ( 医中誌 )

  13. 松本 大亮, 野村 渉, 玉村 啓和: 化合物誘導型ゲノム編集技術の開発 日本バイオマテリアル学会大会予稿集. 2017.11; 39回 162. ( 医中誌 )

  14. 村上 努, 金子 萌美, 藤野 真之, 野村 渉, 玉村 啓和: カプシド蛋白質由来ペプチドを基にした新規抗HIV-1剤の創製 日本エイズ学会誌. 2017.11; 19 (4): 400. ( 医中誌 )

  15. 堀口 諭吉, 合田 達郎, 松元 亮, 武内 寛明, 山岡 昇司, 宮原 裕二: ウイルス認識ナノ粒子を用いた電気抵抗ナノパルス法によるウイルス計測 日本バイオマテリアル学会大会予稿集. 2017.11; 39回 253.

  16. 宮村 憲央, 仁科 博史: モデル生物を用いた肝再生研究 臨床免疫・アレルギー科. 2017.11; 68 (5): 550-555. ( 医中誌 )

  17. 岸田晶夫: 実用化のために必要と考えられる安全性評価について「脱細胞化組織」 バイオマテリアル. 2017.10; 35 (4): 242-247.

  18. 大石　由美子: 脂肪酸代謝リプログラミングによる炎症の収束 感染・炎症・免疫. 2017.10; 47 48-49.

  19. 大石　由美子: 炎症応答の収束にはマクロファージ脂肪酸代謝のリプログラミングが重要である 臨床免疫・アレルギー科. 2017.10; 68 (4): 430-433.

  20. 大石 由美子: 炎症応答の収束にはマクロファージ脂肪酸代謝のリプログラミングが重要である 臨床免疫・アレルギー科. 2017.10; 68 (4): 430-433. ( 医中誌 )

  21. 大石 由美子: 脂肪酸代謝リプログラミングによる炎症の収束 感染・炎症・免疫. 2017.10; 47 (3): 208-209. ( 医中誌 )

  22. 田中 都, 桑田 博仁, 越智 梢, 松本 裕子, 白川 伊吹, 宮原 裕二, 石井 均, 小川 佳宏, 松元 亮, 菅波 孝祥: グルコース応答性ゲルを用いた自律的インスリンデバイスの開発 肥満研究. 2017.09; 23 (Suppl.): 175. ( 医中誌 )

  23. 大石　由美子、真鍋　一郎: 脂肪組織炎症と臓器障害 尿酸と血糖. 2017.09; 3 (3): 163-165.

  24. 渡部 太郎, 永石 宇司, 津川 直也, Nisha Jose, 細谷 明徳, 小島 裕大, 安達 貴弘, 渡辺 守: 回腸粘膜における防御機構としてのIgAの重要性 日本臨床免疫学会会誌. 2017.08; 40 (4): 297. ( 医中誌 )

  25. 永石宇司, 渡部太郎, 細谷明徳, NISHA Jose, 津川直也, 小島裕大, 安達貴弘, 渡辺守: 生体イメージングを応用したIBDモデルにおける腸管粘膜免疫応答の解析 日本臨床免疫学会会誌. 2017.08; 40 (4): 269-269b. ( DOI )

  26. 佐藤 憲子: 【将来に備えて胎児環境を整える-DOHaDを学ぼう-】 DOHaDの基礎　DOHaDの分子機構 産婦人科の実際. 2017.08; 66 (8): 959-966. ( 医中誌 )

  27. 大石 由美子, 真鍋 一郎: 【炎症と臓器障害:尿酸と血糖の関与】脂肪組織炎症と臓器障害 尿酸と血糖. 2017.07; 3 (3): 163-165. ( 医中誌 )

  28. Ikura T., Ito N.: Functional conversion from peptydyl-prolyl isomerase to protease by a single amino acid substitution EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2017.07; 46 S162.

  29. 大石 由美子, 真鍋 一郎: 脂肪組織炎症と臓器障害 (特集 炎症と臓器障害 : 尿酸と血糖の関与) 尿酸と血糖 = Journal of uricemia & glycemic research. 2017.07; 3 (3): 163-165.

  30. 森大典, 栗原康司, Munkhjargal Munkhbayar, 當麻浩司, 荒川貴博, 矢野和義, 三林浩二: 改良型減圧機構を用いたグルコース駆動式薬物放出システムに関する研究 電気学会論文誌Ｅ（センサ・マイクロマシン部門誌）. 2017.06; 137 (6): 174-178. ( DOI )

  31. 大石由美子、真鍋一郎: 脂肪幹細胞システム clinical calsium. 2017.06; 27 (6): 795-801.

  32. 大石 由美子, 真鍋 一郎: 【幹細胞システム】脂肪幹細胞システム Clinical Calcium. 2017.05; 27 (6): 795-801. ( 医中誌 )

  33. 田畑 美幸, Tenaglia Enrico, Guiducci Carlotta, 合田 達郎, 松元 亮, 宮原 裕二: pH検出に基づく小型核酸定量デバイスの創製 生体医歯工学共同研究拠点成果報告書. 2017.04; 平成28年度 58. ( 医中誌 )

  34. 桑田 博仁, 田中 都, 越智 梢, 松本 裕子, 白川 伊吹, 宮原 裕二, 石井 均, 小川 佳宏, 松元 亮, 菅波 孝祥: エレクトロニクスフリーなスマートインスリンデバイスによる新規糖尿病治療戦略の開発 糖尿病. 2017.04; 60 (Suppl.1): S-265. ( 医中誌 )

  35. 松元 亮, 松本 裕子, 諸岡 由佳, 宮原 裕二, 白川 伊吹, 小川 佳宏, 桑田 博仁, 石井 均, 越智 梢, 田中 都, 菅波 孝祥: 完全合成材料による「エレクトロニクスフリー」な人工膵臓の開発 生体医歯工学共同研究拠点成果報告書. 2017.04; 平成28年度 44. ( 医中誌 )

  36. 田中 都, 桑田 博仁, 越智 梢, 松本 裕子, 白川 伊吹, 宮原 裕二, 石井 均, 小川 佳宏, 松元 亮, 菅波 孝祥: スマートインスリンデバイスによる新しい糖尿病治療戦略の開発 日本内分泌学会雑誌. 2017.04; 93 (1): 366. ( 医中誌 )

  37. 棚谷 綾, 佐々木 晴江, 川崎 波留, 増野 弘幸, 河内 恵美子, 伊藤 暢聡, 石田 寛明, 山本 恵子, 平野 真梨子, 影近 弘之: 高いビタミンD活性を有するリトコール酸誘導体の創製 ビタミン. 2017.04; 91 (4): 301. ( 医中誌 )

  38. 田中 都, 桑田 博仁, 越智 梢, 松本 裕子, 白川 伊吹, 宮原 裕二, 石井 均, 小川 佳宏, 松元 亮, 菅波 孝祥: スマートインスリンデバイスによる新しい糖尿病治療戦略の開発 日本内分泌学会雑誌. 2017.04; 93 (1): 366.

  39. 田畑 美幸, Tenaglia Enrico, Guiducci Carlotta, 合田 達郎, 松元 亮, 宮原 裕二: pH検出に基づく小型核酸定量デバイスの創製 生体医歯工学共同研究拠点成果報告書. 2017.04; 平成28年度 58.

  40. 松元 亮, 松本 裕子, 諸岡 由佳, 宮原 裕二, 白川 伊吹, 小川 佳宏, 桑田 博仁, 石井 均, 越智 梢, 田中 都, 菅波 孝祥: 完全合成材料による「エレクトロニクスフリー」な人工膵臓の開発 生体医歯工学共同研究拠点成果報告書. 2017.04; 平成28年度 44.

  41. 三林浩二: バイオ技術を用いたガスセンサ「バイオスニファ」と可視化システム「探嗅カメラ」 Electronics Communications. 2017.03; 32 8-14.

  42. 三林浩二: 非侵襲バイオセンシングおよび住環境ダニアレルゲン計測 グリーンテクノロジー. 2017.03; 27 (3): 58-62.

  43. 三林浩二: 高分子材料とデバイス技術を用いたキャビタス（体腔）バイオセンサ エレクトロニクス実装学会誌. 2017.03; 20 (2): 98-101.

  44. 松元亮: 生体分子との相性が抜群な「ボロン酸工学」の発展を目指して NanoSky. 2017.03;

  45. 大石 由美子, 真鍋 一郎: 【糖尿病研究の"いま"と治療の"これから"】(第1章)インスリン分泌低下はなぜ起きるのか?　マクロファージと膵島炎症　a double-edged sword 実験医学. 2017.02; 35 (2): 175-179. ( 医中誌 )

  46. 橋本良秀, 舩本誠一, 根岸淳, 岸田晶夫: 人工角膜の最前線 材料の科学と工学. 2017.02; 54 (1): 10-13.

  47. 大石由美子、真鍋一郎: 膵島炎症 実験医学増刊「糖尿病研究のいまとこれから」. 2017.02; 35 (2): 175-179.

  48. Nomura W, Tamamura H: [ZIP tag-probe system: A fluorescence imaging tool for intercellular proteins]. Seikagaku. The Journal of Japanese Biochemical Society. 2017.02; 89 (1): 115-20. ( PubMed )

  49. 野村 渉, 玉村 啓和: 細胞内タンパク質を可視化するタグ　蛍光プローブシステム 生化学. 2017.02; 89 (1): 115-119. ( 医中誌 )

  50. 根岸淳, 山下暁立, 舩本誠一: 生体組織・臓器・細胞外マトリックスを原料とする生体材料 材料の科学と工学. 2017.02; 54 (1): 6-9.

  51. 三林浩二: 人をセンシングする 次世代センサ. 2017.01; 26 (2): 1.

  52. 大石由美子、真鍋一郎: 高脂肪食と慢性炎症 炎症と免疫. 2017.01; 25 (1): 51-56.

  53. 野村　渉、玉村啓和: 細胞内タンパク質を可視化するタグ—蛍光プローブシステム 「生化学」みにれびゅう（日本生化学会　東京）. 2017.01; 89 (1): 1-6.

  54. 丹羽　節, 細谷孝充: 低分子PETプローブの開発 日本レーザー医学会誌. 2017.01; 37 (4): 465-472.

  55. 仁科 博史: メダカを用いた肝臓研究 お茶の水医学雑誌. 2017.01; 65 (1): 87-95. ( 医中誌 )

  56. 渡部 太郎, 永石 宇司, 津川 直也, Nisha Jose, 細谷 明徳, 小島 裕大, 安達 貴弘, 渡辺 守: O-5 回腸粘膜における防御機構としてのIgAの重要性 日本臨床免疫学会会誌. 2017; 40 (4): 297a.

  57. 永石 宇司, 渡部 太郎, 細谷 明徳, Nisha Jose, 津川 直也, 小島 裕大, 安達 貴弘, 渡辺 守: WS4-3 生体イメージングを応用したIBDモデルにおける腸管粘膜免疫応答の解析 日本臨床免疫学会会誌. 2017; 40 (4): 269b.

  58. Oishi Y, Manabe I: [Adipose stem cell system.]. Clinical calcium. 2017; 27 (6): 795-801. ( PubMed )

  59. 渡部太郎, 永石宇司, NISHA Jose, 東海有沙, 細谷明徳, 小島裕大, 安達貴弘, 渡辺守: IgAの欠損は回腸粘膜特異的な炎症を誘発する 日本消化管学会総会学術集会プログラム・抄録集. 2017; 13th 252.

  60. 永石 宇司, 渡部 太郎, 細谷 明徳, Nisha Jose, 津川 直也, 小島 裕大, 安達 貴弘, 渡辺 守: WS4-3 生体イメージングを応用したIBDモデルにおける腸管粘膜免疫応答の解析 日本臨床免疫学会会誌. 2017; 40 (4): 269b. ( DOI )

  61. 渡部 太郎, 永石 宇司, 津川 直也, Nisha Jose, 細谷 明徳, 小島 裕大, 安達 貴弘, 渡辺 守: O-5 回腸粘膜における防御機構としてのIgAの重要性 日本臨床免疫学会会誌. 2017; 40 (4): 297a.

  1. 大石　由美子、真鍋　一郎: 脂肪組織炎症におけるB細胞 最新医学. 2016.11; 71 (917): 2217-2221.

  2. 合田 達郎, 今泉 祐輝, 松元 亮, 宮原 裕二: 分析・検査 pH応答トランジスタを用いた細胞膜透過性高分子による膜障害性測定 日本バイオマテリアル学会大会予稿集. 2016.11; シンポジウム2016 201.

  3. 大石　由美子、真鍋　一郎: パラバイオーシスと老化研究 アンチエイジング医学. 2016.10; 12 (5): 650-656.

  4. 大石　由美子、真鍋　一郎: 動脈硬化におけるマクロファージの多様性 医学のあゆみ. 2016.10; 259 (5): 475-479.

  5. 舩本誠一, 木村剛, 岸田晶夫: 生物由来材料を使った人工血管の開発動向 バイオインダストリー. 2016.10; 33 (10): 3-9.

  6. 大石　由美子、真鍋　一郎: Inflammaging 日本臨床. 2016.09; 74 (9): 1441-1445.

  7. 三林浩二: 医療および日常ケアのためのキャビタス（体腔）センサ Cavitas sensors for medicine and daily care 日本印刷学会誌. 2016.08; 53 261-265.

  8. 三林浩二: 非侵襲バイオ計測の展望について 精密工学会誌. 2016.08; 8月号 713-717.

  9. 三林浩二: 呼気中アセトン用センサで脂肪代謝を評価 日本分析化学会第65年会「展望とトッピクス」. 2016.08;

  10. 大石　由美子、真鍋　一郎: Zinc-finger型転写因子 内分泌・糖尿病・代謝内科. 2016.08; 175-180.

  11. Yoshikawa S., Oh-hora M., Adachi T., Yamanishi Y., Karasuyama H.: Stromal interaction molecule-1/2 plays essential role in basophil activation and development of IgE-mediated chronic allergic inflammation EUROPEAN JOURNAL OF IMMUNOLOGY. 2016.08; 46 99.

  12. 木村剛, 呉平麗, 森田裕子, 藤里俊哉, 中村奈緒子, 岸田晶夫: ファイバー被覆化小口径脱細胞化血管の開発 人工臓器. 2016.06; 45 (1): 27-28.

  13. 古川克子, 廣田泰, 吉野修, 岸田晶夫, 牛田多加志, 斉藤滋, 大須賀穣: 子宮の再生 Hormone frontier gynecology. 2016.06; 23 (2): 161-165.

  14. 大石　由美子、真鍋　一郎: マクロファージの転写・エピゲノム・トランスクリプトーム解析 医学のあゆみ. 2016.06; 257 (6): 733-737.

  15. 三林浩二: バイオセンサ技術を用いた気相成分モニタリングおよび可視化計測（住環境ＶＯＣ＆アレルゲン測定への応用） 空気清浄. 2016.05; 54 45-51.

  16. 吉田　優， 喜井　勲，細谷孝充: 2種のアジド分子を効率的に連結する手法の開発 有機合成化学協会誌. 2016.05; 74 (5): 453-461.

  17. 大石　由美子、真鍋　一郎: 代謝疾患における臓器連関と免疫系 医学のあゆみ. 2016.05; 257 (6): 597-600.

  18. 田畑 美幸, Schaffhauser Daniel, 合田 達郎, 松元 亮, 宮原 裕二: 細胞機能の非破壊解析技術の開発 生体材料工学研究所年報. 2016.03; 49 29-32.

  19. 大石　由美子、真鍋　一郎: 慢性炎症と動脈硬化症 臨床化学. 2016.01; 45 (1): 12-17.

  20. 玉村啓和: 中分子創薬の可能性―ペプチドを創薬へと展開するー 現代化学. 2016; (6月号、543): 47-51.

  21. 野村　渉，玉村啓和: 多価型CXCR4リガンドの創製とがん細胞イメージング・検出 医学のあゆみ　第5土曜特集「GPCR研究の最前線2016」. 2016; 256 (5): 430-437.

  22. 荒川貴博, 當麻浩司, 三林浩二: 生体化学情報モニタリングを目指した着脱可能なキャビタス（体腔）センサ　～ソフトコンタクトレンズ型バイオセンサとマウスガード型バイオセンサ～ 人工臓器. 2016; 45 200-203.

  23. 當麻浩司, 鈴木友梨香, 齋藤真奈, 宮島久美子, 荒川貴博, 下村弘治, 三林浩二: インフルエンザウイルスのための化学蛍光法を用いた光ファイバ型免疫測定 生物試料分析. 2016; 39 (4): 271-276.

  24. 大橋南美、玉村啓和: ペプチドミメティックを活用した中分子創薬の研究 化学工業　特集「ペプチド化学の最前線(I)」. 2016; 67 (10): 9-17.

  1. 三林 浩二: コンタクトレンズ型グルコースセンサの開発と非侵襲血糖値評価 ウエアラブル-技術情報協会出版. 2015.12; 483-489.

  2. 三林 浩二: コンタクトレンズ型グルコースセンサ（涙液糖用キャビタス・センサ） システム制御情報学会誌・システム/制御/情報. 2015.11; 59 (11): 418-422.

  3. 田畑 美幸, 合田 達郎, 松元 亮, 宮原 裕二: 自己組織化膜/塩化銀ナノ混合表面の構築と核酸検出バイオセンサへの応用 日本バイオマテリアル学会大会予稿集. 2015.11; 37回 253.

  4. 片山 由梨佳, 田畑 美幸, 合田 達郎, 松元 亮, 星地 彩花, 鈴木 孝治, 宮原 裕二: マイクロpHセンサを用いた等温核酸増幅の電気化学的リアルタイムモニタリング 日本バイオマテリアル学会大会予稿集. 2015.11; 37回 255.

  5. 吉田　優: 歪みの制御に基づく分子連結法の開発 化学と工業. 2015.10; 68 (10): 952-953.

  6. 大石　由美子: マクロファージの細胞代謝と炎症反応 内分泌・糖尿病・代謝内科. 2015.09; 41 (3): 230-234.

  7. 三林 浩二: 疾病や代謝のメカニズムに基づく匂い成分センシングと探嗅カメラ（可視化） におい・かおり環境学会誌. 2015.05; 25 (3): 200-208.

  8. 吉田　優, 細谷孝充: 逐次環化付加反応によるビストリアゾール合成 化学工業. 2015.05; 66 (5): 389-393.

  9. 細谷孝充, 吉田　優: Part II　4章　光親和性標識法の基礎と実際 「生物活性分子のケミカルバイオロジー：標的同定と作用機構（CSJカレントレビュー19）」（日本化学会 編）. 2015.03; 63-70.

  10. 細谷孝充, 吉田　優: Part I　2章　Basic concept-2：標的分子同定の基礎 「生物活性分子のケミカルバイオロジー：標的同定と作用機構（CSJカレントレビュー19）」（日本化学会 編）. 2015.03; 20-25.

  11. 増澤　徹, 服部圭介, 林　照剛, 木村　剛, 岸田晶夫: 磁気ビーズを用いた磁気励振細胞刺激システム 日本ＡＭＥ学会誌. 2015.03; 23 (1): 187-192.

  12. 安田賢二: 1細胞ソーティング：末梢循環がん細胞(CTC)の検出分離 細胞工学. 2015.02; 34 (3): 237-243.

  13. 三林 浩二, 荒川 貴博: センサ医工学における医用計測の展開 次世代センサ. 2015.01; 24 (2): 18-21.

  14. 宮島 久美子, 三林 浩二: 医療・健康科学のためのバイオセンシング クリーンテクノロジー. 2015.01; 18-24.

  15. 山本　誠, 小野木博, 細谷孝充, 萩原正敏: CDK9を標的とした次世代抗ウイルス薬FIT-039の開発 ケミカルバイオロジー. 2015; 8 (1): 2-5.

  16. Kenta Iitani, Toshiyuki Sato, Xin Wang, Koji Toma, Takahiro Arakawa, Kohji Mitsubayashi: 酵素反応を用いた匂いカメラによる手掌部のエタノールガスの可視化計測 Journal of Advanced Science . 2015; 26 (3): 20-22.

  1. 片山 由梨佳, 合田 達郎, 田畑 美幸, 松元 亮, 宮原 裕二: 電気化学測定における金属電極へのタンパク質非特異吸着の影響 日本バイオマテリアル学会大会予稿集. 2014.11; 36回 79.

  2. 飯塚 大介, 合田 達郎, 松元 亮, 宮原 裕二: ボロン酸による二リン酸特異的な分子認識 日本バイオマテリアル学会大会予稿集. 2014.11; 36回 101.

  3. 荒井 貴裕, 前島 雪絵, 合田 達郎, 松元 亮, 大塚 英典, 宮原 裕二: フェニルボロン酸含有高分子層を検出界面とするシアル酸認識バイオトランジスタの創製 日本バイオマテリアル学会大会予稿集. 2014.11; 36回 78.

  4. 片山 由梨佳, 合田 達郎, 田畑 美幸, 松元 亮, 宮原 裕二: 電気化学測定における金属電極へのタンパク質非特異吸着の影響 日本バイオマテリアル学会大会予稿集. 2014.11; 36回 79.

  5. 荒井 貴裕, 前島 雪絵, 合田 達郎, 松元 亮, 大塚 英典, 宮原 裕二: フェニルボロン酸含有高分子層を検出界面とするシアル酸認識バイオトランジスタの創製 日本バイオマテリアル学会大会予稿集. 2014.11; 36回 78.

  6. 安田賢二、野村典正、寺薗英之、服部明弘、金 賢徹: オンチップセロミクスと微細加工技術 バイオマテリアル. 2014.10; 32 (4): 308-323-323.

  7. 安田賢二: CTC検出法と臨床応用 がん分子標的治療. 2014.09; 12 (3): 44-51.

  8. 宮原裕二, 松元亮, 合田達郎, 前田康弘, 田畑美幸, 三條舞: 機能性超分子界面を用いるバイオトランジスタ 超分子材料の設計と応用展開. 2014.09; 2.1.3 78-90.

  9. 星地 彩花, 小塚 ななみ, 田畑 美幸, 松元 亮, 合田 達郎, 宮原 裕二, Citterio Daniel, 鈴木 孝治: イオン選択性電極を用いたリアルタイムDNA増幅検出のための新規測定法 日本分析化学会講演要旨集. 2014.09; 63年会 277.

  10. 細谷孝充, 吉田　優: 第3章　異種アジド基の反応性の差を利用した分子連結 「クリックケミストリー ―基礎から実用まで―」（高田十志和、小山靖人、深瀬浩一 編）. 2014.08; 18-28.

  11. 安田賢二: ヒト細胞を用いた創薬研究支援工学技術の現状と展望 日本再生医療学会雑誌　再生医療. 2014.05; 13 (3): 32-39.

  12. 相澤秀紀, 崔万鵬, 田中光一, 岡本仁: うつ病の病態生理における手綱核神経回路の役割 生体の科学. 2014.02; 65 (1): 12-15.

  13. Yuji Miyahara, Akira Matsumoto, Tatsuro Goda, Yasuhiro Maeda, Miyuki Tabata, Mai Sanjoh: "機能性超分子界面を用いるバイオトランジスタ 超分子材料の設計と応用展開. 2014; 78-90.

  14. Akira Matsumoto, Yuji Miyahara: スマートゲルを利用した完全合成型の“人工膵臓” スマート・ヒューマンセンシング～健康ビッグデータ時代のためのセンサ・情報・エネルギー技術～. 2014; 233-240.

  15. 細谷孝充, 吉田　優: 「くすり（候補）」の効き方を調べるー新しい光親和性標識法の開発. 実験医学増刊「研究成果を薬につなげる アカデミア創薬の戦略と実例」（長野哲雄編）. 2014; 32 (2): 212-221.

  16. Miyuki Tabata, Koziie Noganii, Tatsuro Goda, Akira Matsumoto, Yuji Miyahara: Fabrication of self-assembled monolayer/AGCL mixed surface and it's electrochemical properties IEEJ Transactions on Sensors and Micromachines. 2014; 134 (10): 315-319. ( DOI )

  17. 玉村啓和: ペプチドミメティックスを活用した抗HIV剤の創製 MEDCHEM NEWS（日本薬学会 医薬化学部会　東京）. 2014; 24 (1): 14-19.

  18. 千葉恭敬,　仁科博史: 肝臓形成および肝がんにおけるHippo-YAPシグナル経路の役割 医学のあゆみ . 2014; (251): 405-409.

  19. 畠　星治,　堅田利明, 仁科博史: 器官サイズを調節する転写共役因子YAPの活性制御 生化学. 2014; (86): 464-468.

  1. 木村剛,中村奈緒子,伊東愛,岩田拓也,南広祐,木村俊作,坂口志文,岸田晶夫: 免疫療法を目指したターゲット細胞捕獲デバイスの開発 生体材料工学研究所年報. 2013.12; 47 16-18.

  2. 舩本誠一, 吾郷友亮, 橋本良秀, 根岸淳, 南広祐, 木村剛, 樋上哲哉, 岸田晶夫: 酸素供給マトリクスとしての脱細胞化肝臓の応用 ライフサポート. 2013.11; 25 (3): 76-81.

  3. 山田 恵梨子, 野上 こずえ, 田畑 美幸, 三條 舞, 前田 康弘, 合田 達郎, 松元 亮, 宮原 裕二: 核酸増幅の電気化学的モニタリング 日本バイオマテリアル学会大会予稿集. 2013.11; 35回 155.

  4. 舩本誠一, 吾郷友亮, 橋本良秀, 根岸淳, 南 広祐, 木村　剛, 樋上哲哉, 岸田晶夫: 酸素供給マトリクスとしての脱細胞化肝臓の応用 ライフサポート. 2013.10; 25 (3): 76-81. ( DOI )

  5. 安田賢二: 物理はどこまで生命を理解できるか-物理学からみた「生命科学」のおもしろさ パリティ. 2013.07; 28 (7): 4-5.

  6. 安田賢二: いまこそ読みたい物理の名著　生命とは何か パリティ. 2013.05; 28 (5): 58-59.

  7. 安田賢二: 生体分子がナノ世界でつくり出す「秩序」と「規則性」 パリティ. 2013.03; 28 (3): 1.

  8. 安田賢二: ナノバイオマシンの物理学 パリティ. 2013.03; 28 (3): 4-10.

  9. 安田賢二: 超音波放射圧による生体微粒子ハンドリング 超音波テクノ　. 2013.02; 25 (1): 15-24.

  10. Akira Matsumoto, Yuji Miyahara: 生体計測技術ーバイオセンシングー, Biosensing technology. 人工臓器. 2013; 42 (3): 213-216.

  11. Miyuki Tabata, Tatsuro Goda, Akira Matsumoto, Yuji Miyahara: 機能性ナノ界面を有するバイオトランジスタ, Biotransistor with Functional Nanointerface Containing Biomolecules. 電気学会論文誌E, IEEJ Transactions on Sensors and Micromachines. 2013; 133 (11): B314-B319. ( DOI )

  12. Akira Matsumoto, Takehiko Ishii, Kazunori Kataoka, Yuji Miyahara: Glucose-responsive gel for self-regulated insulin delivery system Drug Delivery System. 2013; 28 (2): 119-126. ( DOI )

  13. Akira Matsumoto, Yuji Miyahara: 生体計測技術ーバイオセンシングー, Biosensing technology. 人工臓器. 2013; 42 (3): 213-216.

  14. 細谷孝充: ダブルクリック反応による新規生体分子標識法. G. I. Research. 2013; 21 (5): 372-378.

  15. 山崎世和,　仁科博史: 脳におけるSAPK/JNKシグナルの役割 CLINICAL NEUROSCIENCE. 2013; (31): 654-656.

  1. 根岸淳、舩本誠一、橋本良秀、南広祐、木村剛、樋上哲哉、岸田晶夫: 脱細胞化動脈の組織学的構造と特性評価 Annual Reports of the Institute of Biomaterials and Bioengineering. 2012.12; 46 (13): 15.

  2. 安田賢二: NEWS　ノーベル医学・生理学賞　人工多能性幹細胞(iPS細胞)の作成 パリティ. 2012.12; 27 (12): 26-28.

  3. 田畑 美幸, 増野 こずえ, 合田 達郎, 松元 亮, 前田 康弘, 片岡 知歩, 井上 裕美, 岩井 秀夫, 宮原 裕二: がんマーカーを検出する簡易デバイスの創製 日本バイオマテリアル学会大会予稿集. 2012.11; シンポジウム2012 468.

  4. 平山　順,　仁科博史: 活性酸素シグナルと概日リズム 実験医学. 2012.11; 36-41.

  5. 安田賢二、金子智行、野村典正: 幹細胞の創薬応用を目指したオンチップ・テクノロジー ファルマシア. 2012.09; 48 (9): 823-825.

  6. 岸田晶夫: 細胞とバイオマテリアル研究 バイオマテリアル. 2012.07; 30 (3): 143-144.

  7. Kudo H, Wang X, Suzuki Y, Ye M, Yamashita T, Gessei T, Miyajima K, Arakawa T, Mitsubayashi K: Fiber-optic biochemical gas sensor (bio-sniffer) for sub-ppb monitoring of formaldehyde vapor. Sensors and Actuators B: Chemical. 2012.04; 161 (1): 486-492.

  8. 金賢徹, 寺薗英之, 竹井弘之, 安田賢二: 多元素微粒子プローブアレイ標識による1細胞in situ発現解析を目指すアダプティブSEMの開発 顕微鏡. 2012.03; 47 (1): 59-64.

  9. 野村渉、田中智博、相川春夫、玉村啓和: 多価結合型GPCRリガンドの合成とがん細胞イメージングへの応用 遺伝子医学MOOK[21]「最新ペプチド合成技術とその創薬研究への応用」. 2012; 267-273.

  10. Akira Matsumoto, Yuji Miyahara: 自律型インスリン投与デバイスの開発状況と将来展望, Current Development Status and Perspective of Self-Regulated Insulin Delivery Systems: A Review. 電気学会論文誌E, IEEJ Transactions on Sensors and Micromachines. 2012; 132 (12): 455-458. ( DOI )

  11. 菅野貴美幸, 吉田　優, 細谷孝充: 異種アジド選択的反応：かさ高い芳香族アジドの意外な反応性の発見. ケミカルバイオロジー. 2012; 5 (1): 11-15.

  12. 細谷孝充, 隅田有人, 吉田　優, 鈴木崇弘、井上　敏: 生物発光系によるin vivoイメージングを指向した発光基質の開発. JSMI Report（日本分子イメージング学会機関誌）. 2012; 6 (1): 3-6.

  13. 喜井　勲, 吉田　優, 細谷孝充: ダブルクリック反応：生体分子の新しい化学修飾法. 生化学. 2012; 84 (4): 306-311.

  14. 玉村啓和: ケミカルバイオロジーを基盤とした抗HIV剤の創製. 薬学雑誌レビュー. 2012; 132 (1): 69-78. ( PubMed )

  15. 野村　渉、田中智博、相川春夫、玉村啓和: 最新ペプチド合成技術とその創薬研究への応用. 多価結合型GPCRリガンドの合成とがん細胞イメージングへの応用(株式会社　メディカルドゥ). 2012; 267-273.

  16. 宮村憲央,　瀬藤光利, 仁科博史: 質量顕微鏡法を用いたマウス再生肝の解析 生化学. 2012; (84): 680-684.

  17. 宮村憲央,　仁科博史: モデル生物を用いた肝発生および肝サイズ制御機構の解明 肝胆膵. 2012; (65): 21-28.

  18. 畠　星治,　仁科博史: Hippoシグナリング シグナル伝達キーワード事典. 2012; 58-60.

  1. 中村奈緒子、橋本良秀、舩本誠一、南広祐、木村剛、藤里俊哉、岩田博夫、岸田晶夫: 脱細胞化骨髄を用いた血液産生システムの再構築 Annual Reports of the Institute of Biomaterials and Bioengineering. 2011.12; 45 11-13.

  2. 安田賢二: iPS細胞で何ができるか～創られたヒト細胞から創薬スクリーニングシステムを ジェトロセンサー. 2011.11; 40-41.

  3. Masahito Hayashi, Hyonchol Kim, Hideyuki Terazono, Akihiko Hattori, Kenji Yasuda, Takashi Ohtsu, Yohei Miyagi, Tokuzo Arao, Kazuto Nishio: CTC計測装置技術の現状と次世代 CTC装置 技術の展望 Cytometry Research. 2011.10; 21 (2): 1-6.

  4. 安田　賢二、金子智行、野村典正: iPS細胞から創られたヒト細胞を用いたin vitro創薬スクリーニングシステム JSAAE News Letter. 2011.10; 40 20-21.

  5. 安田賢二: 末梢循環がん細胞（CTC)計測技術のフロンティア 最新医学. 2011.09; 66 (9): 91-98.

  6. 畑　裕, 仁科博史: 癌・細胞死・再生の新たな鍵を握る器官サイズ制御シグナル 細胞工学. 2011.09; 30 (9):

  7. 安田賢二、金子智行、野村典正: ヒトiPSなどの幹細胞から分化した心筋細胞を用いた不整脈予測法の開発 心電図. 2011.08; 31 (3): 318-324.

  8. 浅岡洋一,　仁科博史: メダカとゼブラフィッシュを用いた肝研究 実験医学. 2011.08; 29 (13): 2090-2095.

  9. 宮原 裕二, 松元 亮, 合田 達郎, 前田 康弘: 界面化学で理解する経口吸収 バイオトランジスタを利用したトランスポータの基質スクリーニング 日本薬剤学会年会講演要旨集. 2011.05; 26年会 33.

  10. 金子智行、野村典正、安田賢二: 東京医科歯科大学生体材料工学研究所情報分野の紹介 応用数理. 2011.03; 21 (1): 58-60.

  11. 安田賢二: Pharmacogenomics for Cancer Therapy　CTC計測技術の最前線 がん分子標的治療. 2011.01; 9 (1): 46-55.

  12. Akira Matsumoto, Yuji Miyahara: ナノバイオセンシングの新展開 New trends in NanoBio-Sensing. Drug Delivery System. 2011; 26 (1): 15-19. ( DOI )

  13. 松元亮, 宮原裕二: バイオセンサの現状と今後の展望. 応用物理. 2011; 80 (3): 205-210.

  14. 仁科博史: モデル生物‐マウスと小型魚類 トランスポートソームの世界－膜輸送研究の源流から未来へ. 2011; 434-439.

  15. 松元亮, 宮原裕二: ナノバイオセンシングの新展開. DDS. 2011; 26 (1): 15-19.

  1. 中村奈緒子、南広祐、木村剛、岸田晶夫、岡田敏行: 生体接着を実現するための高分子表面改質 Annual Reports of the Institute of Biomaterials and Bioengineering. 2010.12; 44 14-15.

  2. 橋本良秀、中村奈緒子、舩本誠一、南広祐、木村剛、岩田博夫、岸田晶夫: 高静水圧処理法による脱細胞化骨・骨髄の作製とin・vitro細胞培養 Annual Reports of the Institute of Biomaterials and Bioengineering. 2010.12; 44 11-13.

  3. 安田賢二: 細胞を並べる技術～再生医療研究からの示唆とその応用～ 日本再生医療学会雑誌　再生医療. 2010.08; 9 (3): 71-82.

  4. 鳴海哲夫、玉村啓和: ペプチドミメティックによる創薬研究. 生化学. 2010.06; 82 (6): 515-523. ( PubMed )

  5. 野村　渉、増田朱美、玉村啓和: エピジェネティクな遺伝子発現制御のためのDNAメチル化酵素の創製. 生化学. 2010.05; 82 (5): 393-397. ( PubMed )

  6. 安田賢二: オンチップ・セロミクス・テクノロジーのヒト幹細胞由来心筋細胞を用いた創薬スクリーニングシステムへの展開 薬学雑誌. 2010.04; 130 (4): 545-557.

  7. 安田賢二: 生命システムの構成的再構築の試み：オンチップ・セロミクス計測技術の開発 日本物理学会誌. 2010.03; 65 (3): 181-186.

  8. 松元亮、宮原裕二: バイオトランジスタの開発. 現代化学. 2010; 54-58.

  9. 仁科博史: 小型魚類メダカを用いた肝形成および肝疾患研究 幹細胞研究会ホームページ. 2010;

  10. 中村　貴, 早坂孝宏, 井上菜穂子, 仁科博史, 瀬藤光利: メタボロームの分布可視化法について メタボロミクス：その解析技術と臨床・創薬応用研究の最前線, メディカルドゥ. 2010; (16): 131-135.

  11. 平山　順,　内田好海、宮村憲央、沢登健治、仁科博史: 概日リズムによる生理機能の制御機構 自律神経. 2010; (47): 297-300.

  1. 木村剛、今野北斗、佐野麻美、南広祐、岸田晶夫: 高圧水圧印加によるプラスミドＤＮＡ凝縮と遺伝子送達への応用 Annual Reports of the Institute of Biomaterials and Bioengineering. 2009.12; 43 11-13.

  2. 安田賢二: オンチップ・セロミクス技術を用いた細胞からのセンシング・バイオロジー 月刊バイオインダストリー. 2009.11; 30-37.

  3. 木村剛、岸田晶夫: 核酸の構造と機能解析における高圧技術-高静水圧下で核酸はどう変化し、何がわかるか？ 月刊化学７月号. 2009.07; 64 (7): 64-65.

  4. Tsuyoshi KIMURA、Sayaka IWAI、Toshiyuki NORITAN、Kwangwoo NAM、Shingo MUTSUO、Hidekazu YOSHIZAWA、Masahiro OKADA、Tsutomu FURUZONO、Toshiya FUJISATO、Akio KISHIDA: 第46回日本人工臓器学会論文賞（広領域）受賞レポート　Preparation of poly (vinyl alcohol) /DNA hydrogels via hydrogen bonds formed on ultra-high pressunzation and controlled release of DNA from the hydrogels for gene delivery 人口臓器. 2009.06; 38 (1): 26-28.

  5. Ikura Teikichi, Kinoshita Kengo, Ito Nobutoshi: [Correlation between structure and function of peptidyl-prolyl isomerase]. Tanpakushitsu Kakusan Koso. 2009.02; 54 (2): 167-172. ( PubMed )

  6. 玉村啓和: 種々の作用点をターゲットとした抗HIV剤の創製. 日本エイズ学会誌　（日本エイズ学会）. 2009; 11 (2): 100-101.

  7. 細谷孝充: 15章　光親和性標識法. 医療・診断ををめざす先端バイオテクノロジー（バイオ研究のフロンティア3）（関根光雄編）. 2009; 141-150.

  8. 玉村啓和: ケモカインレセプターCXCR4をターゲットとしたペプチド創薬研究 薬学研究の進歩. 2009; (25): 33-38. ( 医中誌 )

  1. 安田賢二: 細胞間の物質移動―環境から細胞への物質刺激― 日本機械学会誌. 2008.07; 111 582-585.

  2. 安田賢二: 超音波放射圧による生体微粒子ハンドリング パリティ. 2008.07; 23 (7): 14-23.

  3. 寺田堂彦、木村剛、岸田晶夫、藤里俊哉: バイオスキャフォールド バイオマテリアル. 2008.07; 26 (4): 309-319.

  4. Akira Matsumoto, Yuji Miyahara: Development of Intelligent Polymeric Materials for Controlled Insulin Release to Treat Diabetes Drug Delivery System. 2008.05;

  5. Yuji Miyahara, Toshiya Sakata, Akira Matsumoto, Chiho Kataoka: Detection of Biomolecular Recognition Using Biotransistor Proceedings of the Chemical Sensor Symposium. 2008.03;

  1. 木村剛、柴久美子、加藤綾子、樋上哲哉、増澤徹、岸田晶夫: ステントグラフト内挿術での応用を目指した生体組織-高分子材料接着装置の開発 Annual Reports of the Institute of Biomaterials and Bioengineering. 2007.12; 41 11-14.

  2. 木村剛、舩本誠一、橋本良秀、佐々木秀次、望月學、岸田晶夫、小林尚俊: 脱細胞化角膜の特性とin vivo 生体適合性評価 Annual Reports of the Institute of Biomaterials and Bioengineering. 2007.12; 41

  3. 安田賢二: １細胞からの生命科学：オンチップ細胞機能計測 機能材料. 2007.05; 27 (5): 35-44.

  4. 岸田晶夫: 界面に注目した新しい医用材料開発 バイオマテリアル. 2007.03; 25 (2): 93-104.

  5. 安田賢二: 微量細部対応型オンチップセルソーターシステムの開発 Cytometry Research . 2007.03; 17 (1): 51-57.

  6. 岸田晶夫: 生物学的評価 バイオマテリアル. 2007.01; 25 (1): 43-49.

  7. 細谷孝充: 標的タンパク質探索の化学. 化学工業. 2007; 58 (5): 345-350.

  8. 細谷孝充: アジド基の特性を利用したnon-RI光親和性標識法の開発. 有機合成化学協会誌. 2007; 65 (9): 842-851.

  9. Toshiya Sakata, Akira Matsumoto, Yuji Miyahara: Field Effect-based Biosensing Device. Materials Integration. 2007; 20 50-56.

  1. 木村剛、舩本誠一、橋本良秀、佐々木秀次、望月學、岸田晶夫、小林尚俊: 人工角膜としての脱細胞化角膜の創製 Annual Reports of the Institute of Biomaterials and Bioengineering. 2006.12; 40 16-19.

  2. 寺薗英之, 安田賢二: オンチップ・セロミクス計測システム 日本薬理学雑誌. 2006.09; 132 192-193.

  3. 安田賢二　: オンチップ・セルソーターシステム―細胞の分離から培養まで― バイオサイエンスとインダストリー. 2006.08; 64 (8): 23-26.

  4. 安田賢二　: 単一細胞操作・精製技術（特集ナノバイオロジー：ナノテクでバイオを変える） 細胞工学. 2006.07; 25 (8): 884-889.

  5. 古薗勉、安田昌司、木村剛、京谷晋吾、田中順三、岸田晶夫: 論文賞受賞レポート　Nano-scaled hydroxyapatite/polymer composite IV.Fabrication and cell adhension properties of a three-dimensional scaffold made of composite material with a silk fibroin substrate to develop a percutaneous device　 人工臓器. 2006.06; 35 (1): 170-171.

  6. 安田賢二　: オンチップ細胞分離（セルソーター）システム（テクノトレンド） バイオテクノロジージャーナル. 2006.03; 6 (2): 201-204.

  7. 安田賢二　: NO（脳）と言わない研究者魂　－チップ上に脳を創る－ 未来材料. 2006.02; 6 (2): 68-71.

  8. 玉村啓和: 【ポストゲノム時代の有機化学】　プロテインキナーゼC(PKC)を標的としたDiacylglycerolの環化誘導体の創製 ファルマシア. 2006; 42 (5): 431-435. ( 医中誌 )

  9. 鈴木正昭, 土居久志, 細谷孝充: 生体可視化用分子プローブの創製と活用. オプトロニクス. 2006; 25 (3): 94-100.

  10. 寺井崇二, 浦田洋平, 丸本芳雄, 石川　剛, 青山浩司,　大森　薫, 山本直樹, 坂井田功, 仁科博史, 奥本和夫, 斉藤貴史, 河田純男, 沖田　極,　 : 他施設臨床研究：　肝硬変症に対するAMBI療法の開発 再生医療. 2006; (5): 79-87.

  11. 仁科博史: 一枚の写真館　肝臓に生じたブラックホール？ 細胞工学. 2006; (25):

  12. 北川大樹, 堅田利明, 仁科博史: 新規核内複合体Daxx-RASSF1CはDNA損傷センターとして機能してシグナルを核から細胞質へと伝達する 細胞工学. 2006; (25): 1178-1179.

  13. 玉村啓和: 【統合創薬の開拓】　抗ウイルス薬・抗AIDS(HIV)薬 BIO Clinica. 2006; 21 (3): 224-230. ( 医中誌 )

  1. 岸田晶夫: 再生医療のための脱細胞化生物組織（バイオスキャフォールド） Annual Reports of the Institute of Biomaterials and Bioengineering. 2005.12; 39 9-12.

  2. 岸田晶夫、藤里俊哉: 再生医療用材料 再生医療-日本再生医療学会雑誌. 2005.11; 4 (4): 70-77.

  3. 岸田晶夫: 生体材料の遺伝子発現による評価 材料の化学と工学. 2005.08; 42 (4): 18-22.

  4. 安田賢二: 微細加工技術を用いたオンチップ細胞培養解析システム 応用物理. 2005.07; 74 (7): 890-895.

  5. 古薗勉、岸田晶夫: 再生医療：ナノアパタイト Bio Industry. 2005.05; 22 (5): 54-59.

  6. Adachi T: [Structures and functions of antibodies]. Nihon rinsho. Japanese journal of clinical medicine. 2005.04; 63 Suppl 4 237-42. ( PubMed )

  7. 安田賢二: 微細加工技術を利用したオンチップ細胞培養計測技術の新展開 生体の科学　. 2005.03; 56 (2): 144-149.

  8. 安田賢二: アガロースマイクロ加工チップ上に構築した細胞ネットワークの構成的理解の試み－細胞集団の空間パターンに隠された後天的情報の理解を目指して 化学と工業. 2005.02; 58 (7): 144-146.

  9. 藤井信孝, 大高章, 玉村啓和: 【飛躍するケミカルバイオロジー　化学から生命現象を明らかに】　ケミカルプロテオミクスによる創薬基盤の革新　情報から制御へ 細胞工学. 2005; 24 (11): 1181-1186. ( 医中誌 )

  10. 鈴木正昭, 土居久志, 細谷孝充: 脳化学：PET研究基盤を刷新するプローブ創製と11C新導入法. 神経研究の進歩. 2005; 49 (6): 939-947.

  11. 仁科博史: 細胞を利用した治療 医薬品の開発と生産. 2005; 108-112.

  12. 仁科博史, 堅田利明　: MAPキナーゼ 生物薬科学実験講座　. 2005; 424-433.

  13. 浦　誠司, 仁科博史: MAPキナーゼとストレス応答 シグナル伝達　集中マスター. 2005; 58-67.

  1. 岸田晶夫: 超高圧処理による分子集合体形成 Annual Reports of the Institute of Biomaterials and Bioengineering. 2004.12; 38 9-11.

  2. 安田賢二: II－7. セロミクス研究のためのオンチップ1細胞解析システム 蛋白質 核酸 酵素2004年8月号増刊 バイオ高性能機器・新技術利用マニュアル. 2004.08; 49 (11): 1917-1923.

  3. 安田賢二: 微細加工技術を用いたオンチップ1細胞解析システム、 バイオサイエンスとインダストリー. 2004; 62 (2): 27-30.

  4. 鈴木正昭, 土居久志, 細谷孝充, 渡辺恭良: Positron Emission Tomography（PET）法による生体の分子イメージング研究と創薬・医療への応用. 生物物理. 2004; 44 (6): 265-270. ( DOI )

  5. 岸田晶夫: ナノ振動による幹細胞機能制御法の研究 人工臓器. 2004; 33 (3): 282-283.

  6. 古薗勉、京谷晋呉、田中順三、岸田晶夫: ナノセラミックス複合体による循環器系デバイスの創出 循環器病研究の進歩. 2004; 25 (1): 71-78.

  7. 鈴木正昭, 土居久志, 加藤孝一, 細谷孝充, 渡辺由美子, 渡辺恭良: 脳を探る分子プローブ設計：ヒト脳内IP2受容体の分子イメージング. 日本神経精神薬理学雑誌. 2004; 24 (4): 221-229.

  1. 岸田晶夫: ESCAの測定法と接着 接着の技術. 2003.02; 23 (2): 21-25.

  2. 安田賢二: オンチップセルソーター バイオマテリアル . 2003; 21 (2): 127-132.

  3. 鈴木正昭, 土居久志, 細谷孝充, 渡辺恭良: 生体系の非破壊分析（9）：PET法による脳内中枢型プロスタサイクリン受容体の分子イメージング. 現代化学. 2003; 387 (6): 46-54.

  4. 鈴木正昭, 土居久志, 細谷孝充, Bengt Langstrom, 渡辺由美子, 渡辺恭良: 設計PGプローブによるヒト脳内IP2受容体の分子イメージング. 細胞工学. 2003; 22 (2): 167-171.

  5. 岸田晶夫: 組織工学 人工臓器. 2003; 32 (3): 228-232.

  1. 古薗勉、岸田晶夫、田中順三: シリコーン樹脂とアパタイト複合の経皮デバイス材料 工業材料. 2002.06; 50 (6): 76-80.

  2. Nakamura Haruki, Ito Nobutoshi, Kusunoki Masami: [Development of PDBj: Advanced database for protein structures]. Tanpakushitsu Kakusan Koso. 2002.06; 47 (8 Suppl): 1097-1101. ( PubMed )

  3. 岩瀬満雄、永井耕治、武田基徳、岡田恭慶、大平哲、小栗和也、三林浩二、西義武: 「円筒形マグネトロンガスフロースッパッタリング（CM-GFS）源を用いたPt/TiO2薄膜の成膜. 「粒子線を用いた次世代プロセス技術　応用加速器及び関連技術」論文集. 2002.05; 23-28.

  4. 岸田晶夫: バイオマテリアル　研究とリアリズム バイオマテリアル. 2002.05; 20 (3): 197-198.

  5. 岸田晶夫: 再生医療用材料 日本エム・イー学会雑誌. 2002.02; 16 (2): 18-24.

  1. 岸田晶夫: 医用材料～最近の進歩～ 循環器病研究の進歩. 2001.11; 22 (1): 77-84.

  2. 岸田晶夫: V.表面キャラクタリゼーションの科学（３）X線光電子分光法（XPS） 日本瀬接着学会誌. 2001.02; 37 (2): 84-89.

  3. 井之上一平, 若本祐一, 安田賢二: マイクロチップを利用した1細胞長期培養装置 日本生物物理学会　生物物理. 2001; 41 111-11.

  4. 若本祐一、井之上一平、森口裕之、安田賢二: マイクロチップを利用した１細胞培養システム 日本生化学学会　生化学. 2001; 73 (12): 1439-1443.

  5. 岸田晶夫: 人工材料（有機） 人工臓器. 2001; 30 (3): 123-125.

  1. 田口哲志、岸田晶夫、明石満: 新規な交互浸漬法を用いた高分子－アパタイト複合体の構築 高分子論文集. 2000.06; 57 (6): 324-335.

  2. 岸田晶夫、田口哲志、柳正和、愛甲孝、明石満: 医用材料としての高分子とアパタイトの複合化の検討 高分子論文集. 2000.04; 57 (6): 159-166.

  1. 岸田晶夫: アパタイト複合材料の人工臓器への応用 人工臓器. 1999.08; 28 (3): 607-611.

  2. 岸田晶夫: ハイドロゲルの高機能化による新しい生体材料の開発 生体材料. 1999.08; 17 (4): 180-187.

  3. 鍔田 武志, 安達 貴弘, 若林 千里: CD72によるB細胞活性化制御 (免疫制御の分子生物学) 免疫. 1999.07; (1999): 112-118.

  4. 岸田晶夫: 遺伝子発現による高分子の生体適合性評価 高分子加工. 1999.07; 48 (7): 290-296.

  5. 岸田晶夫: 高分子表面上での骨形成 高分子. 1999.04; 48 (4): 266.

  6. 伊藤　茂: モデルを用いた求核試薬と2, 3-epoxychromone の位置特異的反応機構の分子軌道法による解析 生体材料工学研究所報告. 1999; 33 64-68.

  7. 岸田晶夫: 生体と材料の非特異的相互作用について 生体材料. 1999; 17 (6): 253-256.

  1. 岸田晶夫: 生医学材料としてのブロック共重合体の相構造制御 繊維学会誌. 1998.12; 54 (12): 428-432.

  2. 岸田晶夫、田口哲志、明石満: PVAハイドロゲルの石灰化の検討 ポバール会記録. 1998.12; 113 45-54.

  3. 安田賢二: 超音波輻射圧による生体微粒子操作技術 応用物理. 1998; 67 (3): 323-326.

  4. 玉村　啓和: ケモカイン受容体を標的とした抗HIV剤の開発状況 最新医学. 1998; 53 (9): 2040-2046.

  5. 安田賢二, 八木俊樹　: 超音波輻射圧による生体微粒子操作技術 生物物理　. 1998; 39 (3): 176-178.

  1. 明石満、岸田晶夫、澤智祐、馬場嘉信: 核酸アナローグを用いたキャピラリーアフィニティーゲル電気泳動によるオリゴデオキシヌクレオチドの塩基選択的分離 Jasco Report. 1997.08; 39 (2): 37-43.

  2. 脇 雅宏, 野尻 知里, 城戸 隆行, 杉山 知子, 石原 一彦, 中林 宣男, 岸田 晶夫, 明石 満, 酒井 清孝 : 異なる表面修飾を施したポリウレタン(PU)の血小板粘着挙動の相対評価 人工臓器. 1997.06; 26 (3): 752-755. ( DOI )

  3. 岸田晶夫: Tissue Engineeringと高分子 海外高分子研究. 1997.05; 43 (5): 49-50.

  4. 鈴木正昭, 古田享史, 細谷孝充: 「設計分子による生体機能制御ソフトの構築」を目指して. 有機合成化学協会誌. 1997; 55 (5): 365-374.

  1. 竹内 幸成, 加藤 丈雄, 安達 貴弘, 青木 直人, 松田 幹: ニワトリ卵ZP3ホモログの分子構造および精子との相互作用 日本分子生物学会年会プログラム・講演要旨集. 1996.08; 19

  2. 中瀬 昌之, 堀田 裕貴, 松浦 敦, 松田 幹, 安達 貴弘: イネ種子貯蔵タンパク質αーグロブリン遺伝子に結合するbZIP蛋白質の解析 日本分子生物学会年会プログラム・講演要旨集. 1996.08; 19

  3. 安田賢二、梅村晋一郎、武田一男　: 超音波輻射圧を用いた微粒子分画と濃縮技術のＤＮＡへの応用 超音波テクノ　. 1996.07; 6-9.

  4. 明石満、古薗勉、松本竹男、岸田晶夫: シリコーン成分の表面集積したアラミド・シリコーン樹脂（PAS)の特性と機能 高分子加工. 1996.06; 45 (6): 124-130.

  5. 岸田 晶夫, 丸山 征郎, 明石 満: ヒト・トロンボモジュリン固定化材料の合成と抗血栓性評価 人工臓器. 1996.04; 25 (2): 494-497. ( DOI )

  6. 堀田 裕貴, 安達 貴弘, 青木 直人, 中村 良, 松田 幹: イネ登熟期種子で発現するprotein kinase cDNAのクローニング : 植物 日本農藝化學會誌. 1996.03; 70 (0):

  7. 安達 貴弘, 渡邊 利雄, 大石 道夫, 青木 直人, 松田 幹: マウスMFG-E8およびプチロフィリン遺伝子の染色体マッピング : 動物 日本農藝化學會誌. 1996.03; 70 (0):

  8. 岸 幹也, 大平 幸代, 杉本 昌謙, 青木 直人, 安達 貴弘, 中村 良, 松田 幹: 乳腺細胞膜糖タンパク質MFG-E8の上皮細胞での発現と極性輸送 : 動物 日本農藝化學會誌. 1996.03; 70 (0):

  9. 中瀬 昌之, 堀田 裕貴, 安達 貴弘, 増村 威宏, 田中 國介, 中村 良, 松田 幹: イネ種子α-グロブリン遺伝子の構造とプロモーター領域への核タンパク質の結合 : 植物 日本農藝化學會誌. 1996.03; 70 (0):

  10. 二宮 憲子, 山口 研志, 小林 一清, 安達 貴弘, 青木 直人, 松田 幹: 合成糖鎖高分子の抗体結合特異性と免疫原生 : 糖鎖工学 日本農藝化學會誌. 1996.03; 70 (0):

  11. 山口 研志, 二宮 憲子, 安達 貴弘, 青木 直人, 中村 良, 松田 幹, 岸 聰太郎: 「麦芽タンパク」による食餌性タンパク質抗原に対するlgE抗体応答の抑制 : 食品 日本農藝化學會誌. 1996.03; 70 (0):

  12. 杉山 一男, 福知 幹男, 岸田 晶夫, 明石 満, 門磨 義仁 : ２－メタクリロイルオキシエチルホスホリルコリン／メタクリル酸メチル共重合体をグラフトしたポリエーテルウレタンの合成と性質 高分子論文集. 1996.01; 53 (1): 48-56. ( DOI )

  13. 安田賢二　: 超音波輻射圧を用いた血液成分連続分離の試み。－超音波による赤血球の濃縮とその損傷の検討－ 信学技報　. 1996; US 96 (71): 7-14.

  14. 岸田晶夫: 新しい人工臓器用ポリマー 人工臓器. 1996; 25 (6): 943-951.

  15. 田口哲志、岸田晶夫、坂元伸行、明石　満: 合成高分子ハイドロゲルを用いたサイトカイン担持・放出マトリクスの合成 生体材料. 1996; 14 (4): 152-157.

  1. 安田賢二、梅村晋一郎、武田一男　: 超音波輻射圧による微粒子連続濃縮 超音波テクノ　. 1995.12; 53-56.

  2. 明石満、岸田晶夫、古薗勉: 機能集積表面をもつ新しい抗血栓性材料 化学. 1995.08; 50 (8): 62-63.

  3. 宮下 武也, 中瀬 昌之, 安達 貴弘, 青木 直人, 松田 幹, 中村 良, 宇理須 厚雄: 一群のコメアレルゲンタンパク質のアレルギー患者血清IgEに対する反応特異性 : 食品 日本農藝化學會誌. 1995.07; 69 (0):

  4. 山口 研志, 馬渕 直子, 青木 直人, 安達 貴弘, 松田 幹, 中村 良, 岸 聡太郎, 川崎 正人: 食餌成分による食餌性タンパク質抗原に対する抗体応答の抑制 : 食品 日本農藝化學會誌. 1995.07; 69 (0):

  5. 竹内 幸成, 青木 直人, 安達 貴弘, 松田 幹, 中村 良: ニワトリ卵黄膜内膜42K糖タンパク質のcDNAクローニング : 食品 日本農藝化學會誌. 1995.07; 69 (0):

  6. 岸 幹也, 谷口 陽子, 青木 直人, 安達 貴弘, 松田 幹, 中村 良: ウシ乳脂肪球皮膜糖タンパク質抗原MGP57/53の同定とcDNAクローニング : 食品 日本農藝化學會誌. 1995.07; 69 (0):

  7. 馬渕 直子, 山村 淳一, 青木 直人, 安達 貴弘, 松田 幹, 中村 良: 卵黄β-リベチンとホスビチンのcDNAクローニング : 食品 日本農藝化學會誌. 1995.07; 69 (0):

  8. 泉谷 和歌子, 加藤 保子, 青木 直人, 安達 貴弘, 松田 幹, 中村 良, 後藤 雅広, 野沢 尚子: 非酵素的糖付加に伴う卵白タンパク質の経口免疫原性の増強 : 食品 日本農藝化學會誌. 1995.07; 69 (0):

  9. 岸田晶夫、明石満: 機能性高分子微粒子の医療診断微粒子への応用 高分子加工. 1995.06; 44 (6): 242-247.

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