Sonoda S., Shimada S., Sawada A., Yasuda T., Shirai T., Furusawa H., Tanaka Y., Tanimoto K., Takeuchi H., and Miyazaki Y: Refractory pneumonia due to persistent SARS-CoV-2 infection in an immunocompromised host successfully treated with extended course nirmatrelvir/ ritonavir. ASM Case Reports. 2025.01;
Inoue K., Tomomasa D., Nakagawa Y., Takeuchi H., Tanaka Y., Tanimoto K., Kamiya T., Isoda T., Takagi M., Tanaka K., Yoshifuji K., Miwa Y., Ohnishi H., Okada S., Mori T., Yasuda S., Kido Y., Morio T., and Kanegane H: Real-world experience of tixagevimab and cilgavimab in Japanese patients with immunodeficiency. Journal of Infection and Chemotherapy. 2025.01;
Yasuyuki Kurihara, Takayuki Honda, Akira Takemoto, Katsutoshi Seto, Satoshi Endo, Kousuke Tanimoto, Susumu Kirimura, Masashi Kobayashi, Shunichi Baba, Yasuhiro Nakashima, Ryo Wakejima, Rie Sakakibara, Hironori Ishibashi, Johji Inazawa, Toshihiro Tanaka, Yasunari Miyazaki, Kenichi Okubo: Immunohistochemistry of p53 surrogates TP53 mutation as an accurate predictor for early-relapse of surgically resected stage I-III lung adenocarcinoma JTCVS Open. 2024.08; ( DOI )
Hajime Tanaka, Yuki Fukawa, Kouhei Yamamoto, Kousuke Tanimoto, Akira Takemoto, Takayasu Mori, Hisashi Hasumi, Mayumi Kinoshita, Takumi Kanazawa, Asuka Furukawa, Koichiro Kimura, Hiroyuki Sato, Akihiro Hirakawa, Shohei Fukuda, Yuma Waseda, Soichiro Yoshida, Steven C Campbell, Yasuhisa Fujii: Prognostic impact and genomic backgrounds of renal parenchymal infiltration or micronodular spread in non-metastatic clear cell renal cell carcinoma. Mod Pathol. 2024.08; 100590. ( PubMed , DOI )
Naoya Murao, Taito Matsuda, Hisae Kadowaki, Yosuke Matsushita, Kousuke Tanimoto, Toyomasa Katagiri, Kinichi Nakashima, Hideki Nishitoh: The Derlin-1-Stat5b axis maintains homeostasis of adult hippocampal neurogenesis. EMBO Rep. 2024.07; ( PubMed , DOI )
Osaka H, Tagashira Y, Takeuchi H, Tanaka Y, Tanimoto K, Gu Y: Nosocomial outbreak of SARS-CoV-2 in a hospital ward during the Omicron variant-dominant wave with a review of the relevant literature. Japanese journal of infectious diseases. 2024.05; 77 (5): 253-259. ( PubMed , DOI )
Reda O, Monde K, Sugata K, Rahman A, Sakhor W, Rajib SA, Sithi SN, Tan BJY, Niimura K, Motozono C, Maeda K, Ono M, Takeuchi H, Satou Y: HIV-Tocky system to visualize proviral expression dynamics. Communications biology. 2024.03; 7 (1): 344. ( PubMed , DOI )
Kei Taga, Hiroaki Takeuchi: Novel role of host protein SLC25A42 in the HIV-1 reactivation of latent HIV-1 provirus Microbiology and Immunology. 2024.01; 68 (3): 1-10. ( PubMed , DOI )
Honda T, Seto K, Endo S, Takemoto A, Tanimoto K, Kobayashi M, Kitano M, Sakakibara R, Mitsumura T, Ishibashi H, Inazawa J, Tanaka T, Miyazaki Y, Okubo K: The possibility of mutations of RAS signaling genes and/or TP53 in combination as a negative prognostic impact on pathological stage I non-small cell lung cancer. Cancer medicine. 2023.09; ( PubMed , DOI )
Tatsuya Iida, Jun Ando, Hajime Shinoda, Asami Makino, Mami Yoshimura, Kazue Murai, Makiko Mori, Hiroaki Takeuchi, Takeshi Noda, Hiroshi Nishimasu, Rikiya Watanabe: Compact wide-field femtoliter-chamber imaging system for high-speed and accurate digital bioanalysis. Lab on a Chip. 2023.02; 23 (4): 684-691. ( PubMed , DOI )
Takatsuki Y., Takahashi Y., Nakajima J., Iwasaki Y., Nagano K., Tani-Sassa C., Yuasa S., Kanehira S., Sonobe K., Nukui Y., Takeuchi H., Tanimoto K., Tanaka Y., Kimura A., Ichimura N., and Tohda S.: Viral load of SARS-CoV-2 Omicron BA.5 is lower than that of BA.2 despite higher infectivity of BA.5. Immunity, Inflammation and Disease. 2023.02; 11 (2): e783. ( PubMed , DOI )
Kitamura H., Sukegawa S., Matsuda K., Tanimoto K., Kobayakawa T., Takahashi K., Tamamura H., Tsuchiya K., Gatanaga H., Maeda K., and Takeuchi H.: 4-phenylquinoline-8-amine induces HIV-1 reactivation and apoptosis in latently HIV-1 infected cells. Biochemical and Biophysical Research Communications. 2023.01; 641 139-147. ( PubMed , DOI )
Nishiyama Takara, Takada Toru, Takeuchi Hiroaki, Iwami Shingo: Maternal embryonic leucine zipper kinase (MELK) optimally regulates the HIV-1 uncoating process JOURNAL OF THEORETICAL BIOLOGY. 2022.07; 545 111152. ( PubMed , DOI )
Yuasa S, Nakajima J, Takatsuki Y, Takahashi Y, Tani-Sassa C, Iwasaki Y, Nagano K, Sonobe K, Yoshimoto T, Nukui Y, Takeuchi H, Tanimoto K, Tanaka Y, Kimura A, Ichimura N, Tohda S.: Viral load of SARS-CoV-2 Omicron is not high despite its high infectivity Journal of Medical Virology. 2022.07; 94 (11): 5543-5546. ( PubMed , DOI )
Sayaka Sukegawa and Hiroaki Takeuchi: Toward the unveiling of HIV-1 dynamics: Involvement of monocytes/macrophages in HIV-1 infection Frontiers in Virology. 2022.07; ( DOI )
Shinoda Hajime, Iida Tatsuya, Makino Asami, Yoshimura Mami, Ishikawa Junichiro, Ando Jun, Murai Kazue, Sugiyama Katsumi, Muramoto Yukiko, Nakano Masahiro, Kiga Kotaro, Cui Longzhu, Nureki Osamu, Takeuchi Hiroaki, Noda Takeshi, Nishimasu Hiroshi, Watanabe Rikiya: Automated amplification-free digital RNA detection platform for rapid and sensitive SARS-CoV-2 diagnosis COMMUNICATIONS BIOLOGY. 2022.05; 5 (1): 473. ( PubMed , DOI )
Horiguchi Yukichi, Naono Norihiko, Sakamoto Osamu, Takeuchi Hiroaki, Yamaoka Shoji, Miyahara Yuji: Methodology to Detect Biological Particles Using a Biosensing Surface Integrated in Resistive Pulse Sensing ACS APPLIED MATERIALS & INTERFACES. 2022.04; 14 (17): 20168-20178. ( PubMed , DOI )
Tani-Sassa C, Iwasaki Y, Ichimura N, Nagano K, Takatsuki Y, Yuasa S, Takahashi Y, Nakajima J, Sonobe K, Nukui Y, Takeuchi H, Tanimoto K, Tanaka Y, Kimura A, Tohda S.: Viral loads and profile of the patients infected with SARS-CoV-2 Delta, Alpha, or R.1 variants in Tokyo Journal of Medical Virology. 2022.04; 94 (4): 1707-1710. ( PubMed , DOI )
Inagaki N, Hayashi T, Takei Y, Kosuge H, Suzuki S, Tanimoto K, Chikamori T, Kimura A: Pathogenic variant of RBM20 in a multiplex family with hypertrophic cardiomyopathy. Human genome variation. 2022.02; 9 (1): 6. ( PubMed , DOI )
Arakawa M, Tabata K, Ishida K, Kobayashi M, Arai A, Ishikawa T, Suzuki R, Takeuchi H, Tripathi LP, Mizuguchi K, Morita E: Flavivirus recruits the valosin-containing protein (VCP)/NPL4 complex to induce stress granule disassembly for efficient viral genome replication. The Journal of biological chemistry. 2022.01; 298 (3): 101597. ( PubMed , DOI )
Takemoto A, Tanimoto K, Mori S, Inoue J, Fujiwara N, Noda T, Inazawa J: Integrative genome-wide analyses reveal the transcriptional aberrations in Japanese esophageal squamous cell carcinoma. Cancer science. 2021.10; 112 (10): 4377-4392. ( PubMed , DOI )
Reda O., Monde K., Sugata K., Rahman A., Sakhor W., Tan B. J., Matsuo M., Takeuchi H., Ono M., Satou Y.: A new in-vitro model to monitor HIV-1 proviral transcription by timer-fluorescence protein HIV MEDICINE. 2021.10; 22 54-55.
Liu C, Gen Y, Tanimoto K, Muramatsu T, Inoue J, Inazawa J: Concurrent targeting of MAP3K3 and BRD4 by miR-3140-3p overcomes acquired resistance to BET inhibitors in neuroblastoma cells. Molecular therapy. Nucleic acids. 2021.09; 25 83-92. ( PubMed , DOI )
Deletsu Selase D., Kitamura Haruki, Ishida Takaomi, Gohda Jin, Yamaoka Shoji, Takeuchi Hiroaki: Identification and characterization of Stathmin 1 as a host factor involved in HIV-1 latency BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2021.08; 567 106-111. ( PubMed , DOI )
Nagano K, Tani-Sassa C, Iwasaki Y, Takatsuki Y, Yuasa S, Takahashi Y, Nakajima J, Sonobe K, Ichimura N, Nukui Y, Takeuchi H, Tanimoto K, Tanaka Y, Kimura A, Tohda S: SARS-CoV-2 R.1 lineage variants prevailed in Tokyo in March 2021. Journal of medical virology. 2021.07; 93 (12): 6833-6836. ( PubMed , DOI )
Oba S, Hosoya T, Amamiya M, Mitsumura T, Kawata D, Sasaki H, Kamiya M, Yamamoto A, Ando T, Shimada S, Shirai T, Okamoto T, Tateishi T, Endo A, Aiboshi J, Nosaka N, Yamanouchi H, Ugawa T, Nagaoka E, Oi K, Tao S, Maejima Y, Tanaka Y, Tanimoto K, Takeuchi H, Tohda S, Hirakawa A, Sasano T, Arai H, Otomo Y, Miyazaki Y, Yasuda S: Arterial and Venous Thrombosis Complicated in COVID-19: A Retrospective Single Center Analysis in Japan. Frontiers in cardiovascular medicine. 2021; 8 767074. ( PubMed , DOI )
Lotfi S, Nasser H, Noyori O, Hiyoshi M, Takeuchi H, Koyanagi Y, Suzu S: M-Sec facilitates intercellular transmission of HIV-1 through multiple mechanisms. Retrovirology. 2020.07; 17 (1): 20. ( PubMed , DOI )
Takagawa Y, Gen Y, Muramatsu T, Tanimoto K, Inoue J, Harada H, Inazawa J: miR-1293, a Candidate for miRNA-Based Cancer Therapeutics, Simultaneously Targets BRD4 and the DNA Repair Pathway. Molecular therapy : the journal of the American Society of Gene Therapy. 2020.06; 28 (6): 1494-1505. ( PubMed , DOI )
Hironori Kato, Kohki Okabe, Masato Miyake, Kazuki Hattori, Tomohiro Fukaya, Kousuke Tanimoto, Shi Beini, Mariko Mizuguchi, Satoru Torii, Satoko Arakawa, Masaya Ono, Yusuke Saito, Takashi Sugiyama, Takashi Funatsu, Katsuaki Sato, Shigeomi Shimizu, Seiichi Oyadomari, Hidenori Ichijo, Hisae Kadowaki, Hideki Nishitoh: ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue. Life Science Alliance. 2020.03; 3 (3): ( PubMed , DOI )
Weitong Yao, Takeshi Yoshida, Saki Hashimoto, Hiroaki Takeuchi, Klaus Strebel, Shoji Yamaoka: Vpu of a Simian Immunodeficiency Virus Isolated from Greater Spot-Nosed Monkey Antagonizes Human BST-2 via Two AxxxxxxxW Motifs. J. Virol.. 2020.01; 94 (2): ( PubMed , DOI )
H. Takeuchi, T. Ishida, Y. Satou, J. Gohda, H. Kitamura, S. Gan, K. Takahashi, S. Yamaoka: Genome-wide RNAi screen identifies MAPK-RPK required for HIV-1 proviral silencing in non-T cell reservoir cell-line model Journal of Virus Eradication. 2019.12; 5 (Supplement 3): 5. ( DOI )
Tanimoto K, Muramatsu T, Inazawa J: Massive computational identification of somatic variants in exonic splicing enhancers using The Cancer Genome Atlas. Cancer medicine. 2019.12; 8 (17): 7372-7384. ( PubMed , DOI )
Iwase CS., Miyazato P., Katsuya H., Islam S., Yang TJS., Ito J., Matsuo M., Takeuchi H., Ishida T., Matsuda K., Maeda K., and Satou Y.: HIV-1 DNA-capture-seq is a useful tool for the comprehensive characterization of HIV-1 provirus. Scientific Reports. 2019.08; 9 (1): 12326. ( DOI )
Maeda K., Das D., Kobayakawa T., Tamamura H., and Takeuchi H: Discovery and Development of anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication. Current Topics in Medicinal Chemistry. 2019.07; 19 1-29. ( DOI )
Kenji Maeda, Debananda Das, Takuya Kobayakawa, Hirokazu Tamamura, Hiroaki Takeuchi: Discovery and Development of anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication. Current topics in medicinal chemistry. 2019.07; 19 (18): 1621-1649. ( PubMed , DOI )
Aziati ID, Yoshida T, Hamano A, Maeda K, Takeuchi H, Yamaoka S: PATZ1 is required for efficient HIV-1 infection. Biochemical and biophysical research communications. 2019.06; 514 (2): 538-544. ( PubMed , DOI )
Yoshida Takeshi, Kawamura Saki, Yamaguchi Haruka, Takeuchi Hiroaki, Yamaoka Shoji: Identification of a host factor supporting HIV-1 entry(和訳中) 日本エイズ学会誌. 2018.11; 20 (4): 537. ( ichushi )
Natsuko Inagaki, Takeharu Hayashi, Yasuyoshi Takei, Kousuke Tanimoto, Taishiro Chikamori, Akinori Kimura: Clinical and genetic backgrounds of hypertrophic cardiomyopathy with mid-ventricular obstruction. J. Hum. Genet.. 2018.09; ( PubMed , DOI )
Suzuki N., Yoshida T., Takeuchi H., Sakuma R., Sukegawa S., and Yamaoka S.: Robust enhancement of lentivirus production by promoter activation. Scientific Reports. 2018.09;
Yukichi Horiguchi, Tatsuro Goda, Akira Matsumoto, Hiroaki Takeuchi, Shoji Yamaoka, Yuji Miyahara: Gold Nanoparticles with Ligand/Zwitterion Hybrid Layer for Individual Counting of Influenza A H1N1 Subtype Using Resistive Pulse Sensing. Langmuir. 2018.08; 35 (5): 1798-1806. ( PubMed , DOI )
Takeharu Hayashi, Kousuke Tanimoto, Kayoko Hirayama-Yamada, Etsuko Tsuda, Mamoru Ayusawa, Shinichi Nunoda, Akira Hosaki, Akinori Kimura: Genetic background of Japanese patients with pediatric hypertrophic and restrictive cardiomyopathy. J. Hum. Genet.. 2018.06; ( PubMed , DOI )
Yohei Kawano, Georg Petkau, Christina Stehle, Pawel Durek, Gitta Anne Heinz, Kousuke Tanimoto, Hajime Karasuyama, Mir-Farzin Mashreghi, Chiara Romagnani, Fritz Melchers: Stable lines and clones of long-term proliferating normal, genetically unmodified murine common lymphoid progenitors. Blood. 2018.05; 131 (18): 2026-2035. ( PubMed , DOI )
Jerry Kwame Ndzinu, Hiroaki Takeuchi, Hideki Saito, Takeshi Yoshida, Shoji Yamaoka: eIF4A2 is a host factor required for efficient HIV-1 replication. Microbes Infect.. 2018.05; 20 (6): 346-352. ( PubMed , DOI )
Tonouchi E, Gen Y, Muramatsu T, Hiramoto H, Tanimoto K, Inoue J, Inazawa J: miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein SCIENTIFIC REPORTS. 2018.03; 8 (1): 4482. ( PubMed , DOI )
Jin Gohda, Kazuo Suzuki, Kai Liu, Xialin Xie, Hiroaki Takeuchi, Jun-Ichiro Inoue, Yasushi Kawaguchi, Takaomi Ishida: BI-2536 and BI-6727, dual Polo-like kinase/bromodomain inhibitors, effectively reactivate latent HIV-1. Sci Rep. 2018.02; 8 (1): 3521. ( PubMed , DOI )
Osako M., Itsumi M., Yamaguchi H., Takeuchi H., and Yamaoka S.: A20 restores phorbol ester-induced differentiation of THP-1 cells in the absence of nuclear factor-κB activation. Journal of Cellular Biochemistry. 2018.02; 119 (2): 1475-1487. ( PubMed , DOI )
Hai W., Goda T., Takeuchi H., Yamaoka S., Horiguchi Y., Matsumoto A., and Miyahara Y: Human Influenza Virus Detection Using Sialyllactose-Functionalized Organic Electrochemical Transistors. Sensors & Actuators B-Chemical. 2018.01;
Takeshi Yoshida, Akiko Hamano, Asuka Ueda, Hiroaki Takeuchi, Shoji Yamaoka: Human SMOOTHENED inhibits human immunodeficiency virus type 1 infection. Biochem. Biophys. Res. Commun.. 2017.11; 493 (1): 132-138. ( PubMed , DOI )
Hideki Saito, Hiroaki Takeuchi, Takao Masuda, Takeshi Noda, Shoji Yamaoka: N-terminally truncated POM121C inhibits HIV-1 replication. PLoS ONE. 2017.09; 12 (9): e0182434. ( PubMed , DOI )
Shin Hayashi, Daniela Tiaki Uehara, Kousuke Tanimoto, Seiji Mizuno, Yasutsugu Chinen, Shinobu Fukumura, Jun-Ichi Takanashi, Hitoshi Osaka, Nobuhiko Okamoto, Johji Inazawa: Comprehensive investigation of CASK mutations and other genetic etiologies in 41 patients with intellectual disability and microcephaly with pontine and cerebellar hypoplasia (MICPCH). PLoS ONE. 2017.08; 12 (8): e0181791. ( PubMed , DOI )
Hiroaki Takeuchi, Hideki Saito, Takeshi Noda, Tadashi Miyamoto, Tomokazu Yoshinaga, Kazutaka Terahara, Hiroshi Ishii, Yasuko Tsunetsugu-Yokota, Shoji Yamaoka: Phosphorylation of the HIV-1 capsid by MELK triggers uncoating to promote viral cDNA synthesis. PLoS Pathog. 2017.07; 13 (7): e1006441. ( PubMed , DOI )
Hidekazu Hiramoto, Tomoki Muramatsu, Daisuke Ichikawa, Kousuke Tanimoto, Satoru Yasukawa, Eigo Otsuji, Johji Inazawa: miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer. Sci Rep. 2017.06; 7 (1): 4002. ( PubMed , DOI )
Hiroaki Nagata, Ken-Ichi Kozaki, Tomoki Muramatsu, Hidekazu Hiramoto, Kousuke Tanimoto, Naoto Fujiwara, Seiya Imoto, Daisuke Ichikawa, Eigo Otsuji, Satoru Miyano, Tatsuyuki Kawano, Johji Inazawa: Genome-wide screening of DNA methylation associated with lymph node metastasis in esophageal squamous cell carcinoma. Oncotarget. 2017.06; 8 (23): 37740-37750. ( PubMed , DOI )
Yukichi Horiguchi, Tatsuro Goda, Akira Matsumoto, Hiroaki Takeuchi, Shoji Yamaoka, Yuji Miyahara: Direct and label-free influenza virus detection based on multisite binding to sialic acid receptors. Biosens Bioelectron. 2017.06; 92 234-240. ( PubMed , DOI )
Wenfeng H., Goda T., Takeuchi H., Yamaoka S., Horiguchi Y., Akira M., and Miyahara Y.: Specific Recognition of Human Influenza Virus with PEDOT Bearing Sialic Acid-Terminated Trisaccharides. ACS Applied Materials & Interfaces. 2017.04; 9 (16): 14162-14170. ( PubMed , DOI )
Yu Oikawa, Kei-Ichi Morita, Kou Kayamori, Kousuke Tanimoto, Kei Sakamoto, Hiroto Katoh, Shumpei Ishikawa, Johji Inazawa, Hiroyuki Harada: Receptor tyrosine kinase amplification is predictive of distant metastasis in patients with oral squamous cell carcinoma. Cancer Sci.. 2017.02; 108 (2): 256-266. ( PubMed , DOI )
Mai Nanya, Masaki Sato, Kousuke Tanimoto, Minoru Tozuka, Shuki Mizutani, Masatoshi Takagi: Dysregulation of the DNA Damage Response and KMT2A Rearrangement in Fetal Liver Hematopoietic Cells. PLoS ONE. 2015.12; 10 (12): e0144540. ( PubMed , DOI )
Morita K, Naruto T, Tanimoto K, Yasukawa C, Oikawa Y, Masuda K, Imoto I, Inazawa J, Omura K, Harada H: Simultaneous detection of both single nucleotide variations and copy number alterations by next-generation sequencing in gorlin syndrome. PLOS One. 2015.11; 10 (11): e0140480. ( PubMed , DOI )
Naoto Fujiwara, Jun Inoue, Tatsuyuki Kawano, Kousuke Tanimoto, Ken-Ichi Kozaki, Johji Inazawa: miR-634 Activates the Mitochondrial Apoptosis Pathway and Enhances Chemotherapy-Induced Cytotoxicity. Cancer Res.. 2015.09; 75 (18): 3890-3901. ( PubMed , DOI )
Sukegawa S., Sakuma R., Ohmine S., Takeuchi H., Ikeda Y and Yamaoka S.: Suppressor of Cytokine Signaling 1 Counteracts Rhesus Macaque TRIM5a-Induced Inhibition of Human Immunodeficiency Virus Type-1 Production. PLoS ONE. 2014.09; 9 (10): e109640. ( PubMed )
Sotaro Kanematsu, Kousuke Tanimoto, Yutaka Suzuki, Sumio Sugano: Screening for possible miRNA-mRNA associations in a colon cancer cell line. Gene. 2014.01; 533 (2): 520-531. ( PubMed , DOI )
Sugiyama R., Abe M., Nishitsuji H., Murakami Y., Takeuchi H., and Takaku H.: Induction of heat-shock protein 70 by prostaglandin A1 inhibits HIV-1 Vif-mediated degradation of APOBEC3G. Antiviral Research. 2013.09; 99 (3): 307-311. ( PubMed )
Takanori Hori, Hiroaki Takeuchi, Hideki Saito, Ryuta Sakuma, Yoshio Inagaki, Shoji Yamaoka: A carboxy-terminally truncated human CPSF6 lacking residues encoded by exon 6 inhibits HIV-1 cDNA synthesis and promotes capsid disassembly. J. Virol.. 2013.07; 87 (13): 7726-7736. ( PubMed , DOI )
Furuta M, Kozaki K, Tanimoto K, Tanaka S, Arii S, Shimamura T, Niida A, Miyano S, Inazawa J: The tumor-suppressive miR-497-195 cluster targets multiple cell-cycle regulators in hepatocellular carcinoma. PLoS One. 2013; 8 (3): e60155. ( PubMed , DOI )
Ryuta Sakuma, Hiroaki Takeuchi: SIV replication in human cells. Front Microbiol. 2012.04; 3 162. ( PubMed , DOI )
Hiroaki Takeuchi, Hiroshi Ishii, Tetsuya Kuwano, Natsuko Inagaki, Hirofumi Akari, Tetsuro Matano: Host cell species-specific effect of cyclosporine A on simian immunodeficiency virus replication. Retrovirology. 2012.01; 9 3. ( PubMed , DOI )
Akinori Kanai, Kenta Suzuki, Kousuke Tanimoto, Junko Mizushima-Sugano, Yutaka Suzuki, Sumio Sugano: Characterization of STAT6 target genes in human B cells and lung epithelial cells. DNA Res.. 2011.10; 18 (5): 379-392. ( PubMed , DOI )
Riu Yamashita, Nuankanya P Sathira, Akinori Kanai, Kousuke Tanimoto, Takako Arauchi, Yoshiaki Tanaka, Shin-Ichi Hashimoto, Sumio Sugano, Kenta Nakai, Yutaka Suzuki: Genome-wide characterization of transcriptional start sites in humans by integrative transcriptome analysis. Genome Res.. 2011.05; 21 (5): 775-789. ( PubMed , DOI )
Sugiyama R., Nishitsuji H., Furukawa A., Katahira M., Habu Y., Takeuchi H., Ryo A., and Takaku H.: Heat shock protein 70 inhibits HIV-1 Vif-mediated ubiquitination and degradation of APOBEC3G. Journal of Biological Chemistry. 2011; 286 (12): 10051-10057.
Ohmine S., Sakuma R., Sakuma T., Thatava T., Takeuchi H., and Ikeda Y.: The antiviral spectra of TRIM5α orthologues and human TRIM family proteins against lentiviral production. PLoS ONE. 2011; 6 (1): e16121.
Kousuke Tanimoto, Katsuya Tsuchihara, Akinori Kanai, Takako Arauchi, Hiroyasu Esumi, Yutaka Suzuki, Sumio Sugano: Genome-wide identification and annotation of HIF-1α binding sites in two cell lines using massively parallel sequencing. Hugo J. 2010.12; 4 (1-4): 35-48. ( PubMed , DOI )
Nuankanya Sathira, Riu Yamashita, Kousuke Tanimoto, Akinori Kanai, Takako Arauchi, Soutaro Kanematsu, Kenta Nakai, Yutaka Suzuki, Sumio Sugano: Characterization of transcription start sites of putative non-coding RNAs by multifaceted use of massively paralleled sequencer. DNA Res.. 2010.06; 17 (3): 169-183. ( PubMed , DOI )
Hiroaki Takeuchi: Contribution of Cyclophilin A to determination of simian immunodeficiency virus tropism: a progress update. Vaccine. 2010.05; 28 Suppl 2 B51-B54. ( PubMed , DOI )
Iwamoto N., Tsukamoto T., Kawada M., Takeda A., Yamamoto H., Takeuchi H., and Matano T.: Broadening of CD8+ cell responses in vaccine-based simian immunodeficiency virus controllers. AIDS. 2010; 24 (18): 2777-2787.
Inagaki N., Takeuchi H*., Yokoyama M., Sato H., Ryo A., Yamamoto H., Kawada M., and Matano T.: A structural constraint for functional interaction between N-terminal and C-terminal domains in simian immunodeficiency virus capsid proteins. Retrovirology. 2010; (7): 90.
Katsuya Tsuchihara, Yutaka Suzuki, Hiroyuki Wakaguri, Takuma Irie, Kousuke Tanimoto, Shin-ichi Hashimoto, Kouji Matsushima, Junko Mizushima-Sugano, Riu Yamashita, Kenta Nakai, David Bentley, Hiroyasu Esumi, Sumio Sugano: Massive transcriptional start site analysis of human genes in hypoxia cells. Nucleic Acids Res.. 2009.04; 37 (7): 2249-2263. ( PubMed , DOI )
Hiroaki Takeuchi, Tetsuro Matano: Host factors involved in resistance to retroviral infection. Microbiol. Immunol.. 2008.06; 52 (6): 318-325. ( PubMed , DOI )
Kawada M., Tsukamoto T., Yamamoto H., Iwamoto N., Kurihara K., Takeda A., Moriya C., Takeuchi H., Akari H., and Matano T.: Gag-specific cytotoxic T-lymphocyte-based control of primary simian immunodeficiency virus replication in a vaccine trial. Journal of Virology. 2008; 82 (20): 10199-10206.
Goila-Gaur R., Khan MA., Miyagi E., Kao S., Opi S., Takeuchi H., and Strebel K.: HIV-1 Vif promotes the formation of high molecular mass APOBEC3G complexes. Virology. 2008; 372 (1): 136-146.
Hiroaki Takeuchi, Alicia Buckler-White, Ritu Goila-Gaur, Eri Miyagi, Mohammad A Khan, Sandrine Opi, Sandra Kao, Elena Sokolskaja, Thomas Pertel, Jeremy Luban, Klaus Strebel: Vif counteracts a cyclophilin A-imposed inhibition of simian immunodeficiency viruses in human cells. J. Virol.. 2007.08; 81 (15): 8080-8090. ( PubMed , DOI )
Kao S., Goila-Gaur R., Miyagi E., Kahn MA., Opi S., Takeuchi H., and Strebel K. : Production of infectious virus and degradation of APOBEC3G are separable functional properties of human immunodeficiency virus type 1 Vif. Virology. 2007; 369 (2): 329-339.
Miyagi E., Opi S., Takeuchi H., Khan MA., Goila-Gaur R., Kao S., and Strebel K. : Enzymatically Active APOBEC3G Is required for Efficient Inhibition of HIV-1. Journal of Virology. 2007; 81 (24): 13346-13353.
Opi S., Kao S., Goila-Gaur R., Khan MA., Miyagi E., Takeuchi H., and Strebel K. : Human immunodeficiency virus type 1 Vif inhibits packaging and antiviral activity of a degradation-resistant APOBEC3G variant. Journal of Virology. 2007; 81 (15): 8236-8246.
Khan MA., Goila-Gaur R., Opi S., Miyagi E., Takeuchi H., Kao S., and Strebel K. : Analysis of the contribution of cellular and viral RNA to the packaging of APOBEC3G into HIV-1 virions. Retrovirology. 2007; 4 (1): 48.
Iwatani Y., Takeuchi H*., Strebel K., and Levin JG.: Biochemical activities of highly purified, catalytically active human APOBEC3G: correlation with antiviral effect. Journal of Virology. 2006; 80 (12): 5992-6002.
Eda Y., Murakami T., Ami Y., Nakasone T., Takizawa M., Someya K., Kaizu M., Izumi Y., Yoshino N., Matsushita S., Higuchi H., Matsui H., Shinohara K., Takeuchi H., Koyanagi Y., Yamamoto N., and Honda M.: Anti-V3 Humanized Antibody KD-247 Effectively Suppresses Ex Vivo Generation of Human Immunodeficiency Virus Type 1 and Affords Sterile Protection of Monkeys against a Heterologous Simian/Human Immunodeficiency Virus Infection. Journal of Virology. 2006; 80 (11): 5563-5570.
Opi S., Takeuchi H*., Kao S., Khan MA., Miyagi E., Goila-Gaur R., Iwatani Y., Levin LG., and Strebel K.: Monomeric APOBEC3G is catalytically active and has antiviral activity. Journal of Virology. 2006; 80 (10): 4673-4682.
Hiroaki Takeuchi, Sandra Kao, Eri Miyagi, Mohammad A Khan, Alicia Buckler-White, Ron Plishka, Klaus Strebel: Production of infectious SIVagm from human cells requires functional inactivation but not viral exclusion of human APOBEC3G. J. Biol. Chem.. 2005.01; 280 (1): 375-382. ( PubMed , DOI )
Khan MA., Kao S., Miyagi E., Takeuchi H., Goila-Gaur R., Opi S., Gipson CL., Parslow TG., Ly H., and Strebel K. : Viral RNA is required for the Association of APOBEC3G with HIV-1 Nucleoprotein Complexes. Journal of Virology. 2005; 79 (9): 5870-5874.
Habu Y., Nagawa T., Matsumoto N., Takeuchi H., Miyano-Kurosaki N., and Takaku H.: Suppression of human immunodeficiency virus type 1 (HIV-1) replication by an HIV-1-dependent double locked vector with the Cre/loxP system. Nucleosides Nucleotides Nucleic Acids. 2005; 24 (10-12): 1907-1917.
Miyano-Kurosaki N., Barnor JS., Takeuchi H., Owada T., Nakashima H., Yamamoto N., Matsuzaki T., Shimada F., and Takaku H.: In vitro and in vivo transport and delivery of phosphorothioate oligonucleotides with cationic liposomes. Antiviral Chemistry and Chemotherapy. 2004; 15 (2): 93-100.
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Kuwasaki T., Hatta M., Takeuchi H., and Takaku H.: Inhibition of human immunodeficiency virus 1 replication in vitro by a self-stabilized oligonucleotide with 2'-O-methyl-guanosine-uridine quadruplex motifs. Journal of Antimicrobial Chemotherapy. 2003; 51 (4): 813-819.
Hiroaki Takeuchi, Youichi Suzuki, Masashi Tatsumi, Hiroo Hoshino, Eric S Daar, Yoshio Koyanagi: Isolation and characterization of an infectious HIV type 1 molecular clone from a patient with primary infection. AIDS Res. Hum. Retroviruses. 2002.10; 18 (15): 1127-1133. ( PubMed , DOI )
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Inagawa T., Nakashima H., Karwowski B., Guga P., Stec WJ., Takeuchi H., and Takaku H.: Inhibition of Human Immunodeficiency Virus Type-1 replication by P-stereodefined oligo (nucleoside phosphorothioate)s in a long-term infection model. FEBS Letter . 2002; 528 (1-3): 48-52.
Nagawa T., Habu Y., Matsumoto N., Takeuchi H., Miyano-Kurosaki N., and Takaku H.: Development of HIV-1 dependent gene expression vector with the Cre/loxP (ON) system. Nucleic Acids Resarch. 2002; Supplement 2 295-296.
Habu Y., Miyano-Kurosaki N., Nagawa T., Matsumoto N., Takeuchi H*., and Takaku H.: Inhibition of HIV-1 replication by an HIV-1 dependent ribozyme expression vector with the Cre/loxP (ON/OFF) system. Antiviral Chemistry and Chemotherapy. 2002; 13 (5): 273-281.
Yukita M., Kitano M., Miyano-Kurosaki N., Takeuchi H., Nashimoto M., and Takaku H.: RNA cleavage by a mammalian tRNA 3' processing endoribonuclease (3'tRNase) reduces HIV-1 expression. Nucleic Acids Resarch. 2002; Supplement 2 297-298.
Habu Y., Miyano-Kurosaki N., Takeuchi H., Matsumoto N., Tamura Y., and Takaku H.: Inhibition of HIV-1 replication by the Cre-loxP hammerhead ribozyme. Nucleosides Nucleotides Nucleic Acids. 2001; 20 (4-7): 723-726.
Kitano M., Barnor JS., Miyano-Kurosaki N., Endo Y., Yukita M., Takeuchi H., Tamura Y., Takai K., Nashimoto M., and Takaku H.: Effective suppression of HIV-1 gene expression by a mammalian tRNA 3' processing endoribonuclease and external guide sequence oligozymes. Nucleosides Nucleotides Nucleic Acids. 2001; 20 (4-7): 719-722.
Habu Y., Takeuchi H*., Tamura Y., Miyano-Kurosaki N., Takai K., and Takaku H.: Development of an HIV-1-dependent expression vector with the Cre/loxP system. Nucleic Acids Symposium Series. 1999; (42): 295-296.
Suzuki J., Miyano-Kurosaki N., Takeuchi H., Tamura Y., Kawai G., Takai K., Tanaka Y., Tanaka R., Yamamoto N., and Takaku H.: Phosphorothioate G3T4G3 motifs inhibit the early stage of HIV-1 infection. Nucleic Acids Symposium Series. 1999; (42): 227-228.
Kitano M., Miyano-Kurosaki N., Endo Y., Yukita M., Takeuchi H., Tamura Y., Takai K., Nashimoto M., and Takaku H. : Effective suppression of HIV-1 gene expression by a mammalian tRNA 3' processing endoribonuclease and external guide sequence oligozymes. Nucleic Acids Symposium Series. 1999; (42): 207-208.
Hosoya T., Takeuchi H*., Kanesaka Y., Yamakawa H., Miyano-Kurosaki N., Takai K., Yamamoto N., and Takaku H.: Sequence-specific inhibition of a transcription factor by circular dumbbell DNA oligonucleotides. FEBS Letters . 1999; 19 (461 (3)): 136-140.
Tsukahara S., Suzuki J., Goto Y., Inagawa T., Takeuchi H., Takai K., Koyanagi Y., Yamamoto N., and Takaku H.: Inhibition of gene expression by oligonucleotides forming triple-helices with the polypurine tract of HIV-1. Nucleic Acids Symposium Series. 1996; (35): 181-182.
Kousuke Tanimoto, Taeko K Naruse, Akinori Kimura: Non-human MHC genotyping methods using next generation sequencing 2019.08; 26 (2): 115-123. ( DOI )
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