1. Sonoda S., Shimada S., Sawada A., Yasuda T., Shirai T., Furusawa H., Tanaka Y., Tanimoto K., Takeuchi H., and Miyazaki Y: Refractory pneumonia due to persistent SARS-CoV-2 infection in an immunocompromised host successfully treated with extended course nirmatrelvir/ ritonavir. ASM Case Reports. 2025.01;

  2. Inoue K., Tomomasa D., Nakagawa Y., Takeuchi H., Tanaka Y., Tanimoto K., Kamiya T., Isoda T., Takagi M., Tanaka K., Yoshifuji K., Miwa Y., Ohnishi H., Okada S., Mori T., Yasuda S., Kido Y., Morio T., and Kanegane H: Real-world experience of tixagevimab and cilgavimab in Japanese patients with immunodeficiency. Journal of Infection and Chemotherapy. 2025.01;

  1. Yasuyuki Kurihara, Takayuki Honda, Akira Takemoto, Katsutoshi Seto, Satoshi Endo, Kousuke Tanimoto, Susumu Kirimura, Masashi Kobayashi, Shunichi Baba, Yasuhiro Nakashima, Ryo Wakejima, Rie Sakakibara, Hironori Ishibashi, Johji Inazawa, Toshihiro Tanaka, Yasunari Miyazaki, Kenichi Okubo: Immunohistochemistry of p53 surrogates TP53 mutation as an accurate predictor for early-relapse of surgically resected stage I-III lung adenocarcinoma JTCVS Open. 2024.08; ( DOI )

  2. Hajime Tanaka, Yuki Fukawa, Kouhei Yamamoto, Kousuke Tanimoto, Akira Takemoto, Takayasu Mori, Hisashi Hasumi, Mayumi Kinoshita, Takumi Kanazawa, Asuka Furukawa, Koichiro Kimura, Hiroyuki Sato, Akihiro Hirakawa, Shohei Fukuda, Yuma Waseda, Soichiro Yoshida, Steven C Campbell, Yasuhisa Fujii: Prognostic impact and genomic backgrounds of renal parenchymal infiltration or micronodular spread in non-metastatic clear cell renal cell carcinoma. Mod Pathol. 2024.08; 100590. ( PubMed , DOI )

  3. Naoya Murao, Taito Matsuda, Hisae Kadowaki, Yosuke Matsushita, Kousuke Tanimoto, Toyomasa Katagiri, Kinichi Nakashima, Hideki Nishitoh: The Derlin-1-Stat5b axis maintains homeostasis of adult hippocampal neurogenesis. EMBO Rep. 2024.07; ( PubMed , DOI )

  4. Osaka H, Tagashira Y, Takeuchi H, Tanaka Y, Tanimoto K, Gu Y: Nosocomial outbreak of SARS-CoV-2 in a hospital ward during the Omicron variant-dominant wave with a review of the relevant literature. Japanese journal of infectious diseases. 2024.05; 77 (5): 253-259. ( PubMed , DOI )

  5. Reda O, Monde K, Sugata K, Rahman A, Sakhor W, Rajib SA, Sithi SN, Tan BJY, Niimura K, Motozono C, Maeda K, Ono M, Takeuchi H, Satou Y: HIV-Tocky system to visualize proviral expression dynamics. Communications biology. 2024.03; 7 (1): 344. ( PubMed , DOI )

  6. Kei Taga, Hiroaki Takeuchi: Novel role of host protein SLC25A42 in the HIV-1 reactivation of latent HIV-1 provirus Microbiology and Immunology. 2024.01; 68 (3): 1-10. ( PubMed , DOI )

  1. Honda T, Seto K, Endo S, Takemoto A, Tanimoto K, Kobayashi M, Kitano M, Sakakibara R, Mitsumura T, Ishibashi H, Inazawa J, Tanaka T, Miyazaki Y, Okubo K: The possibility of mutations of RAS signaling genes and/or TP53 in combination as a negative prognostic impact on pathological stage I non-small cell lung cancer. Cancer medicine. 2023.09; ( PubMed , DOI )

  2. Tatsuya Iida, Jun Ando, Hajime Shinoda, Asami Makino, Mami Yoshimura, Kazue Murai, Makiko Mori, Hiroaki Takeuchi, Takeshi Noda, Hiroshi Nishimasu, Rikiya Watanabe: Compact wide-field femtoliter-chamber imaging system for high-speed and accurate digital bioanalysis. Lab on a Chip. 2023.02; 23 (4): 684-691. ( PubMed , DOI )

  3. Takatsuki Y., Takahashi Y., Nakajima J., Iwasaki Y., Nagano K., Tani-Sassa C., Yuasa S., Kanehira S., Sonobe K., Nukui Y., Takeuchi H., Tanimoto K., Tanaka Y., Kimura A., Ichimura N., and Tohda S.: Viral load of SARS-CoV-2 Omicron BA.5 is lower than that of BA.2 despite higher infectivity of BA.5. Immunity, Inflammation and Disease. 2023.02; 11 (2): e783. ( PubMed , DOI )

  4. Kitamura H., Sukegawa S., Matsuda K., Tanimoto K., Kobayakawa T., Takahashi K., Tamamura H., Tsuchiya K., Gatanaga H., Maeda K., and Takeuchi H.: 4-phenylquinoline-8-amine induces HIV-1 reactivation and apoptosis in latently HIV-1 infected cells. Biochemical and Biophysical Research Communications. 2023.01; 641 139-147. ( PubMed , DOI )

  1. Nishiyama Takara, Takada Toru, Takeuchi Hiroaki, Iwami Shingo: Maternal embryonic leucine zipper kinase (MELK) optimally regulates the HIV-1 uncoating process JOURNAL OF THEORETICAL BIOLOGY. 2022.07; 545 111152. ( PubMed , DOI )

  2. Yuasa S, Nakajima J, Takatsuki Y, Takahashi Y, Tani-Sassa C, Iwasaki Y, Nagano K, Sonobe K, Yoshimoto T, Nukui Y, Takeuchi H, Tanimoto K, Tanaka Y, Kimura A, Ichimura N, Tohda S.: Viral load of SARS-CoV-2 Omicron is not high despite its high infectivity Journal of Medical Virology. 2022.07; 94 (11): 5543-5546. ( PubMed , DOI )

  3. Sayaka Sukegawa and Hiroaki Takeuchi: Toward the unveiling of HIV-1 dynamics: Involvement of monocytes/macrophages in HIV-1 infection Frontiers in Virology. 2022.07; ( DOI )

  4. Shinoda Hajime, Iida Tatsuya, Makino Asami, Yoshimura Mami, Ishikawa Junichiro, Ando Jun, Murai Kazue, Sugiyama Katsumi, Muramoto Yukiko, Nakano Masahiro, Kiga Kotaro, Cui Longzhu, Nureki Osamu, Takeuchi Hiroaki, Noda Takeshi, Nishimasu Hiroshi, Watanabe Rikiya: Automated amplification-free digital RNA detection platform for rapid and sensitive SARS-CoV-2 diagnosis COMMUNICATIONS BIOLOGY. 2022.05; 5 (1): 473. ( PubMed , DOI )

  5. Horiguchi Yukichi, Naono Norihiko, Sakamoto Osamu, Takeuchi Hiroaki, Yamaoka Shoji, Miyahara Yuji: Methodology to Detect Biological Particles Using a Biosensing Surface Integrated in Resistive Pulse Sensing ACS APPLIED MATERIALS & INTERFACES. 2022.04; 14 (17): 20168-20178. ( PubMed , DOI )

  6. Tani-Sassa C, Iwasaki Y, Ichimura N, Nagano K, Takatsuki Y, Yuasa S, Takahashi Y, Nakajima J, Sonobe K, Nukui Y, Takeuchi H, Tanimoto K, Tanaka Y, Kimura A, Tohda S.: Viral loads and profile of the patients infected with SARS-CoV-2 Delta, Alpha, or R.1 variants in Tokyo Journal of Medical Virology. 2022.04; 94 (4): 1707-1710. ( PubMed , DOI )

  7. Inagaki N, Hayashi T, Takei Y, Kosuge H, Suzuki S, Tanimoto K, Chikamori T, Kimura A: Pathogenic variant of RBM20 in a multiplex family with hypertrophic cardiomyopathy. Human genome variation. 2022.02; 9 (1): 6. ( PubMed , DOI )

  8. Arakawa M, Tabata K, Ishida K, Kobayashi M, Arai A, Ishikawa T, Suzuki R, Takeuchi H, Tripathi LP, Mizuguchi K, Morita E: Flavivirus recruits the valosin-containing protein (VCP)/NPL4 complex to induce stress granule disassembly for efficient viral genome replication. The Journal of biological chemistry. 2022.01; 298 (3): 101597. ( PubMed , DOI )

  1. Takemoto A, Tanimoto K, Mori S, Inoue J, Fujiwara N, Noda T, Inazawa J: Integrative genome-wide analyses reveal the transcriptional aberrations in Japanese esophageal squamous cell carcinoma. Cancer science. 2021.10; 112 (10): 4377-4392. ( PubMed , DOI )

  2. Reda O., Monde K., Sugata K., Rahman A., Sakhor W., Tan B. J., Matsuo M., Takeuchi H., Ono M., Satou Y.: A new in-vitro model to monitor HIV-1 proviral transcription by timer-fluorescence protein HIV MEDICINE. 2021.10; 22 54-55.

  3. Liu C, Gen Y, Tanimoto K, Muramatsu T, Inoue J, Inazawa J: Concurrent targeting of MAP3K3 and BRD4 by miR-3140-3p overcomes acquired resistance to BET inhibitors in neuroblastoma cells. Molecular therapy. Nucleic acids. 2021.09; 25 83-92. ( PubMed , DOI )

  4. Deletsu Selase D., Kitamura Haruki, Ishida Takaomi, Gohda Jin, Yamaoka Shoji, Takeuchi Hiroaki: Identification and characterization of Stathmin 1 as a host factor involved in HIV-1 latency BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2021.08; 567 106-111. ( PubMed , DOI )

  5. Nagano K, Tani-Sassa C, Iwasaki Y, Takatsuki Y, Yuasa S, Takahashi Y, Nakajima J, Sonobe K, Ichimura N, Nukui Y, Takeuchi H, Tanimoto K, Tanaka Y, Kimura A, Tohda S: SARS-CoV-2 R.1 lineage variants prevailed in Tokyo in March 2021. Journal of medical virology. 2021.07; 93 (12): 6833-6836. ( PubMed , DOI )

  6. Oba S, Hosoya T, Amamiya M, Mitsumura T, Kawata D, Sasaki H, Kamiya M, Yamamoto A, Ando T, Shimada S, Shirai T, Okamoto T, Tateishi T, Endo A, Aiboshi J, Nosaka N, Yamanouchi H, Ugawa T, Nagaoka E, Oi K, Tao S, Maejima Y, Tanaka Y, Tanimoto K, Takeuchi H, Tohda S, Hirakawa A, Sasano T, Arai H, Otomo Y, Miyazaki Y, Yasuda S: Arterial and Venous Thrombosis Complicated in COVID-19: A Retrospective Single Center Analysis in Japan. Frontiers in cardiovascular medicine. 2021; 8 767074. ( PubMed , DOI )

  1. Lotfi S, Nasser H, Noyori O, Hiyoshi M, Takeuchi H, Koyanagi Y, Suzu S: M-Sec facilitates intercellular transmission of HIV-1 through multiple mechanisms. Retrovirology. 2020.07; 17 (1): 20. ( PubMed , DOI )

  2. Takagawa Y, Gen Y, Muramatsu T, Tanimoto K, Inoue J, Harada H, Inazawa J: miR-1293, a Candidate for miRNA-Based Cancer Therapeutics, Simultaneously Targets BRD4 and the DNA Repair Pathway. Molecular therapy : the journal of the American Society of Gene Therapy. 2020.06; 28 (6): 1494-1505. ( PubMed , DOI )

  3. Hironori Kato, Kohki Okabe, Masato Miyake, Kazuki Hattori, Tomohiro Fukaya, Kousuke Tanimoto, Shi Beini, Mariko Mizuguchi, Satoru Torii, Satoko Arakawa, Masaya Ono, Yusuke Saito, Takashi Sugiyama, Takashi Funatsu, Katsuaki Sato, Shigeomi Shimizu, Seiichi Oyadomari, Hidenori Ichijo, Hisae Kadowaki, Hideki Nishitoh: ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue. Life Science Alliance. 2020.03; 3 (3): ( PubMed , DOI )

  4. Weitong Yao, Takeshi Yoshida, Saki Hashimoto, Hiroaki Takeuchi, Klaus Strebel, Shoji Yamaoka: Vpu of a Simian Immunodeficiency Virus Isolated from Greater Spot-Nosed Monkey Antagonizes Human BST-2 via Two AxxxxxxxW Motifs. J. Virol.. 2020.01; 94 (2): ( PubMed , DOI )

  1. H. Takeuchi, T. Ishida, Y. Satou, J. Gohda, H. Kitamura, S. Gan, K. Takahashi, S. Yamaoka: Genome-wide RNAi screen identifies MAPK-RPK required for HIV-1 proviral silencing in non-T cell reservoir cell-line model Journal of Virus Eradication. 2019.12; 5 (Supplement 3): 5. ( DOI )

  2. Tanimoto K, Muramatsu T, Inazawa J: Massive computational identification of somatic variants in exonic splicing enhancers using The Cancer Genome Atlas. Cancer medicine. 2019.12; 8 (17): 7372-7384. ( PubMed , DOI )

  3. Iwase CS., Miyazato P., Katsuya H., Islam S., Yang TJS., Ito J., Matsuo M., Takeuchi H., Ishida T., Matsuda K., Maeda K., and Satou Y.: HIV-1 DNA-capture-seq is a useful tool for the comprehensive characterization of HIV-1 provirus. Scientific Reports. 2019.08; 9 (1): 12326. ( DOI )

  4. Maeda K., Das D., Kobayakawa T., Tamamura H., and Takeuchi H: Discovery and Development of anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication. Current Topics in Medicinal Chemistry. 2019.07; 19 1-29. ( DOI )

  5. Kenji Maeda, Debananda Das, Takuya Kobayakawa, Hirokazu Tamamura, Hiroaki Takeuchi: Discovery and Development of anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication. Current topics in medicinal chemistry. 2019.07; 19 (18): 1621-1649. ( PubMed , DOI )

  6. Aziati ID, Yoshida T, Hamano A, Maeda K, Takeuchi H, Yamaoka S: PATZ1 is required for efficient HIV-1 infection. Biochemical and biophysical research communications. 2019.06; 514 (2): 538-544. ( PubMed , DOI )

  1. Yoshida Takeshi, Kawamura Saki, Yamaguchi Haruka, Takeuchi Hiroaki, Yamaoka Shoji: Identification of a host factor supporting HIV-1 entry(和訳中) 日本エイズ学会誌. 2018.11; 20 (4): 537. ( 医中誌 )

  2. Natsuko Inagaki, Takeharu Hayashi, Yasuyoshi Takei, Kousuke Tanimoto, Taishiro Chikamori, Akinori Kimura: Clinical and genetic backgrounds of hypertrophic cardiomyopathy with mid-ventricular obstruction. J. Hum. Genet.. 2018.09; ( PubMed , DOI )

  3. Suzuki N., Yoshida T., Takeuchi H., Sakuma R., Sukegawa S., and Yamaoka S.: Robust enhancement of lentivirus production by promoter activation. Scientific Reports. 2018.09;

  4. Yukichi Horiguchi, Tatsuro Goda, Akira Matsumoto, Hiroaki Takeuchi, Shoji Yamaoka, Yuji Miyahara: Gold Nanoparticles with Ligand/Zwitterion Hybrid Layer for Individual Counting of Influenza A H1N1 Subtype Using Resistive Pulse Sensing. Langmuir. 2018.08; 35 (5): 1798-1806. ( PubMed , DOI )

  5. Takeharu Hayashi, Kousuke Tanimoto, Kayoko Hirayama-Yamada, Etsuko Tsuda, Mamoru Ayusawa, Shinichi Nunoda, Akira Hosaki, Akinori Kimura: Genetic background of Japanese patients with pediatric hypertrophic and restrictive cardiomyopathy. J. Hum. Genet.. 2018.06; ( PubMed , DOI )

  6. Yohei Kawano, Georg Petkau, Christina Stehle, Pawel Durek, Gitta Anne Heinz, Kousuke Tanimoto, Hajime Karasuyama, Mir-Farzin Mashreghi, Chiara Romagnani, Fritz Melchers: Stable lines and clones of long-term proliferating normal, genetically unmodified murine common lymphoid progenitors. Blood. 2018.05; 131 (18): 2026-2035. ( PubMed , DOI )

  7. Jerry Kwame Ndzinu, Hiroaki Takeuchi, Hideki Saito, Takeshi Yoshida, Shoji Yamaoka: eIF4A2 is a host factor required for efficient HIV-1 replication. Microbes Infect.. 2018.05; 20 (6): 346-352. ( PubMed , DOI )

  8. Tonouchi E, Gen Y, Muramatsu T, Hiramoto H, Tanimoto K, Inoue J, Inazawa J: miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein SCIENTIFIC REPORTS. 2018.03; 8 (1): 4482. ( PubMed , DOI )

  9. Jin Gohda, Kazuo Suzuki, Kai Liu, Xialin Xie, Hiroaki Takeuchi, Jun-Ichiro Inoue, Yasushi Kawaguchi, Takaomi Ishida: BI-2536 and BI-6727, dual Polo-like kinase/bromodomain inhibitors, effectively reactivate latent HIV-1. Sci Rep. 2018.02; 8 (1): 3521. ( PubMed , DOI )

  10. Osako M., Itsumi M., Yamaguchi H., Takeuchi H., and Yamaoka S.: A20 restores phorbol ester-induced differentiation of THP-1 cells in the absence of nuclear factor-κB activation. Journal of Cellular Biochemistry. 2018.02; 119 (2): 1475-1487. ( PubMed , DOI )

  11. Hai W., Goda T., Takeuchi H., Yamaoka S., Horiguchi Y., Matsumoto A., and Miyahara Y: Human Influenza Virus Detection Using Sialyllactose-Functionalized Organic Electrochemical Transistors. Sensors & Actuators B-Chemical. 2018.01;

  1. Takeshi Yoshida, Akiko Hamano, Asuka Ueda, Hiroaki Takeuchi, Shoji Yamaoka: Human SMOOTHENED inhibits human immunodeficiency virus type 1 infection. Biochem. Biophys. Res. Commun.. 2017.11; 493 (1): 132-138. ( PubMed , DOI )

  2. Hideki Saito, Hiroaki Takeuchi, Takao Masuda, Takeshi Noda, Shoji Yamaoka: N-terminally truncated POM121C inhibits HIV-1 replication. PLoS ONE. 2017.09; 12 (9): e0182434. ( PubMed , DOI )

  3. Shin Hayashi, Daniela Tiaki Uehara, Kousuke Tanimoto, Seiji Mizuno, Yasutsugu Chinen, Shinobu Fukumura, Jun-Ichi Takanashi, Hitoshi Osaka, Nobuhiko Okamoto, Johji Inazawa: Comprehensive investigation of CASK mutations and other genetic etiologies in 41 patients with intellectual disability and microcephaly with pontine and cerebellar hypoplasia (MICPCH). PLoS ONE. 2017.08; 12 (8): e0181791. ( PubMed , DOI )

  4. Hiroaki Takeuchi, Hideki Saito, Takeshi Noda, Tadashi Miyamoto, Tomokazu Yoshinaga, Kazutaka Terahara, Hiroshi Ishii, Yasuko Tsunetsugu-Yokota, Shoji Yamaoka: Phosphorylation of the HIV-1 capsid by MELK triggers uncoating to promote viral cDNA synthesis. PLoS Pathog. 2017.07; 13 (7): e1006441. ( PubMed , DOI )

  5. Hidekazu Hiramoto, Tomoki Muramatsu, Daisuke Ichikawa, Kousuke Tanimoto, Satoru Yasukawa, Eigo Otsuji, Johji Inazawa: miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer. Sci Rep. 2017.06; 7 (1): 4002. ( PubMed , DOI )

  6. Hiroaki Nagata, Ken-Ichi Kozaki, Tomoki Muramatsu, Hidekazu Hiramoto, Kousuke Tanimoto, Naoto Fujiwara, Seiya Imoto, Daisuke Ichikawa, Eigo Otsuji, Satoru Miyano, Tatsuyuki Kawano, Johji Inazawa: Genome-wide screening of DNA methylation associated with lymph node metastasis in esophageal squamous cell carcinoma. Oncotarget. 2017.06; 8 (23): 37740-37750. ( PubMed , DOI )

  7. Yukichi Horiguchi, Tatsuro Goda, Akira Matsumoto, Hiroaki Takeuchi, Shoji Yamaoka, Yuji Miyahara: Direct and label-free influenza virus detection based on multisite binding to sialic acid receptors. Biosens Bioelectron. 2017.06; 92 234-240. ( PubMed , DOI )

  8. Wenfeng H., Goda T., Takeuchi H., Yamaoka S., Horiguchi Y., Akira M., and Miyahara Y.: Specific Recognition of Human Influenza Virus with PEDOT Bearing Sialic Acid-Terminated Trisaccharides. ACS Applied Materials & Interfaces. 2017.04; 9 (16): 14162-14170. ( PubMed , DOI )

  9. Yu Oikawa, Kei-Ichi Morita, Kou Kayamori, Kousuke Tanimoto, Kei Sakamoto, Hiroto Katoh, Shumpei Ishikawa, Johji Inazawa, Hiroyuki Harada: Receptor tyrosine kinase amplification is predictive of distant metastasis in patients with oral squamous cell carcinoma. Cancer Sci.. 2017.02; 108 (2): 256-266. ( PubMed , DOI )

  1. Daisuke Kikuchi, Kousuke Tanimoto, Koh Nakayama: CREB is activated by ER stress and modulates the unfolded protein response by regulating the expression of IRE1α and PERK. Biochem. Biophys. Res. Commun.. 2016.01; 469 (2): 243-250. ( PubMed , DOI )

  1. Mai Nanya, Masaki Sato, Kousuke Tanimoto, Minoru Tozuka, Shuki Mizutani, Masatoshi Takagi: Dysregulation of the DNA Damage Response and KMT2A Rearrangement in Fetal Liver Hematopoietic Cells. PLoS ONE. 2015.12; 10 (12): e0144540. ( PubMed , DOI )

  2. Morita K, Naruto T, Tanimoto K, Yasukawa C, Oikawa Y, Masuda K, Imoto I, Inazawa J, Omura K, Harada H: Simultaneous detection of both single nucleotide variations and copy number alterations by next-generation sequencing in gorlin syndrome. PLOS One. 2015.11; 10 (11): e0140480. ( PubMed , DOI )

  3. Naoto Fujiwara, Jun Inoue, Tatsuyuki Kawano, Kousuke Tanimoto, Ken-Ichi Kozaki, Johji Inazawa: miR-634 Activates the Mitochondrial Apoptosis Pathway and Enhances Chemotherapy-Induced Cytotoxicity. Cancer Res.. 2015.09; 75 (18): 3890-3901. ( PubMed , DOI )

  1. Sukegawa S., Sakuma R., Ohmine S., Takeuchi H., Ikeda Y and Yamaoka S.: Suppressor of Cytokine Signaling 1 Counteracts Rhesus Macaque TRIM5a-Induced Inhibition of Human Immunodeficiency Virus Type-1 Production. PLoS ONE. 2014.09; 9 (10): e109640. ( PubMed )

  2. Sotaro Kanematsu, Kousuke Tanimoto, Yutaka Suzuki, Sumio Sugano: Screening for possible miRNA-mRNA associations in a colon cancer cell line. Gene. 2014.01; 533 (2): 520-531. ( PubMed , DOI )

  1. Sugiyama R., Abe M., Nishitsuji H., Murakami Y., Takeuchi H., and Takaku H.: Induction of heat-shock protein 70 by prostaglandin A1 inhibits HIV-1 Vif-mediated degradation of APOBEC3G. Antiviral Research. 2013.09; 99 (3): 307-311. ( PubMed )

  2. Takanori Hori, Hiroaki Takeuchi, Hideki Saito, Ryuta Sakuma, Yoshio Inagaki, Shoji Yamaoka: A carboxy-terminally truncated human CPSF6 lacking residues encoded by exon 6 inhibits HIV-1 cDNA synthesis and promotes capsid disassembly. J. Virol.. 2013.07; 87 (13): 7726-7736. ( PubMed , DOI )

  3. Furuta M, Kozaki K, Tanimoto K, Tanaka S, Arii S, Shimamura T, Niida A, Miyano S, Inazawa J: The tumor-suppressive miR-497-195 cluster targets multiple cell-cycle regulators in hepatocellular carcinoma. PLoS One. 2013; 8 (3): e60155. ( PubMed , DOI )

  1. Ryuta Sakuma, Hiroaki Takeuchi: SIV replication in human cells. Front Microbiol. 2012.04; 3 162. ( PubMed , DOI )

  2. Hiroaki Takeuchi, Hiroshi Ishii, Tetsuya Kuwano, Natsuko Inagaki, Hirofumi Akari, Tetsuro Matano: Host cell species-specific effect of cyclosporine A on simian immunodeficiency virus replication. Retrovirology. 2012.01; 9 3. ( PubMed , DOI )

  1. Akinori Kanai, Kenta Suzuki, Kousuke Tanimoto, Junko Mizushima-Sugano, Yutaka Suzuki, Sumio Sugano: Characterization of STAT6 target genes in human B cells and lung epithelial cells. DNA Res.. 2011.10; 18 (5): 379-392. ( PubMed , DOI )

  2. Riu Yamashita, Nuankanya P Sathira, Akinori Kanai, Kousuke Tanimoto, Takako Arauchi, Yoshiaki Tanaka, Shin-Ichi Hashimoto, Sumio Sugano, Kenta Nakai, Yutaka Suzuki: Genome-wide characterization of transcriptional start sites in humans by integrative transcriptome analysis. Genome Res.. 2011.05; 21 (5): 775-789. ( PubMed , DOI )

  3. Sugiyama R., Nishitsuji H., Furukawa A., Katahira M., Habu Y., Takeuchi H., Ryo A., and Takaku H.: Heat shock protein 70 inhibits HIV-1 Vif-mediated ubiquitination and degradation of APOBEC3G. Journal of Biological Chemistry. 2011; 286 (12): 10051-10057.

  4. Ohmine S., Sakuma R., Sakuma T., Thatava T., Takeuchi H., and Ikeda Y.: The antiviral spectra of TRIM5α orthologues and human TRIM family proteins against lentiviral production. PLoS ONE. 2011; 6 (1): e16121.

  1. Kousuke Tanimoto, Katsuya Tsuchihara, Akinori Kanai, Takako Arauchi, Hiroyasu Esumi, Yutaka Suzuki, Sumio Sugano: Genome-wide identification and annotation of HIF-1α binding sites in two cell lines using massively parallel sequencing. Hugo J. 2010.12; 4 (1-4): 35-48. ( PubMed , DOI )

  2. Nuankanya Sathira, Riu Yamashita, Kousuke Tanimoto, Akinori Kanai, Takako Arauchi, Soutaro Kanematsu, Kenta Nakai, Yutaka Suzuki, Sumio Sugano: Characterization of transcription start sites of putative non-coding RNAs by multifaceted use of massively paralleled sequencer. DNA Res.. 2010.06; 17 (3): 169-183. ( PubMed , DOI )

  3. Hiroaki Takeuchi: Contribution of Cyclophilin A to determination of simian immunodeficiency virus tropism: a progress update. Vaccine. 2010.05; 28 Suppl 2 B51-B54. ( PubMed , DOI )

  4. Iwamoto N., Tsukamoto T., Kawada M., Takeda A., Yamamoto H., Takeuchi H., and Matano T.: Broadening of CD8+ cell responses in vaccine-based simian immunodeficiency virus controllers. AIDS. 2010; 24 (18): 2777-2787.

  5. Inagaki N., Takeuchi H*., Yokoyama M., Sato H., Ryo A., Yamamoto H., Kawada M., and Matano T.: A structural constraint for functional interaction between N-terminal and C-terminal domains in simian immunodeficiency virus capsid proteins. Retrovirology. 2010; (7): 90.

  1. Katsuya Tsuchihara, Yutaka Suzuki, Hiroyuki Wakaguri, Takuma Irie, Kousuke Tanimoto, Shin-ichi Hashimoto, Kouji Matsushima, Junko Mizushima-Sugano, Riu Yamashita, Kenta Nakai, David Bentley, Hiroyasu Esumi, Sumio Sugano: Massive transcriptional start site analysis of human genes in hypoxia cells. Nucleic Acids Res.. 2009.04; 37 (7): 2249-2263. ( PubMed , DOI )

  1. Hiroaki Takeuchi, Tetsuro Matano: Host factors involved in resistance to retroviral infection. Microbiol. Immunol.. 2008.06; 52 (6): 318-325. ( PubMed , DOI )

  2. Kawada M., Tsukamoto T., Yamamoto H., Iwamoto N., Kurihara K., Takeda A., Moriya C., Takeuchi H., Akari H., and Matano T.: Gag-specific cytotoxic T-lymphocyte-based control of primary simian immunodeficiency virus replication in a vaccine trial. Journal of Virology. 2008; 82 (20): 10199-10206.

  3. Goila-Gaur R., Khan MA., Miyagi E., Kao S., Opi S., Takeuchi H., and Strebel K.: HIV-1 Vif promotes the formation of high molecular mass APOBEC3G complexes. Virology. 2008; 372 (1): 136-146.

  1. Hiroaki Takeuchi, Alicia Buckler-White, Ritu Goila-Gaur, Eri Miyagi, Mohammad A Khan, Sandrine Opi, Sandra Kao, Elena Sokolskaja, Thomas Pertel, Jeremy Luban, Klaus Strebel: Vif counteracts a cyclophilin A-imposed inhibition of simian immunodeficiency viruses in human cells. J. Virol.. 2007.08; 81 (15): 8080-8090. ( PubMed , DOI )

  2. Kao S., Goila-Gaur R., Miyagi E., Kahn MA., Opi S., Takeuchi H., and Strebel K. : Production of infectious virus and degradation of APOBEC3G are separable functional properties of human immunodeficiency virus type 1 Vif. Virology. 2007; 369 (2): 329-339.

  3. Miyagi E., Opi S., Takeuchi H., Khan MA., Goila-Gaur R., Kao S., and Strebel K. : Enzymatically Active APOBEC3G Is required for Efficient Inhibition of HIV-1. Journal of Virology. 2007; 81 (24): 13346-13353.

  4. Opi S., Kao S., Goila-Gaur R., Khan MA., Miyagi E., Takeuchi H., and Strebel K. : Human immunodeficiency virus type 1 Vif inhibits packaging and antiviral activity of a degradation-resistant APOBEC3G variant. Journal of Virology. 2007; 81 (15): 8236-8246.

  5. Khan MA., Goila-Gaur R., Opi S., Miyagi E., Takeuchi H., Kao S., and Strebel K. : Analysis of the contribution of cellular and viral RNA to the packaging of APOBEC3G into HIV-1 virions. Retrovirology. 2007; 4 (1): 48.

  1. Iwatani Y., Takeuchi H*., Strebel K., and Levin JG.: Biochemical activities of highly purified, catalytically active human APOBEC3G: correlation with antiviral effect. Journal of Virology. 2006; 80 (12): 5992-6002.

  2. Eda Y., Murakami T., Ami Y., Nakasone T., Takizawa M., Someya K., Kaizu M., Izumi Y., Yoshino N., Matsushita S., Higuchi H., Matsui H., Shinohara K., Takeuchi H., Koyanagi Y., Yamamoto N., and Honda M.: Anti-V3 Humanized Antibody KD-247 Effectively Suppresses Ex Vivo Generation of Human Immunodeficiency Virus Type 1 and Affords Sterile Protection of Monkeys against a Heterologous Simian/Human Immunodeficiency Virus Infection. Journal of Virology. 2006; 80 (11): 5563-5570.

  3. Opi S., Takeuchi H*., Kao S., Khan MA., Miyagi E., Goila-Gaur R., Iwatani Y., Levin LG., and Strebel K.: Monomeric APOBEC3G is catalytically active and has antiviral activity. Journal of Virology. 2006; 80 (10): 4673-4682.

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  1. Kuwasaki T., Hatta M., Takeuchi H., and Takaku H.: Inhibition of human immunodeficiency virus 1 replication in vitro by a self-stabilized oligonucleotide with 2'-O-methyl-guanosine-uridine quadruplex motifs. Journal of Antimicrobial Chemotherapy. 2003; 51 (4): 813-819.

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  4. Hosoya T., Takeuchi H*., Kanesaka Y., Yamakawa H., Miyano-Kurosaki N., Takai K., Yamamoto N., and Takaku H.: Sequence-specific inhibition of a transcription factor by circular dumbbell DNA oligonucleotides. FEBS Letters . 1999; 19 (461 (3)): 136-140.

  1. Tsukahara S., Suzuki J., Goto Y., Inagawa T., Takeuchi H., Takai K., Koyanagi Y., Yamamoto N., and Takaku H.: Inhibition of gene expression by oligonucleotides forming triple-helices with the polypurine tract of HIV-1. Nucleic Acids Symposium Series. 1996; (35): 181-182.

  1. Fujikawa Taro, Tanimoto Kousuke, Kawashima Yoshiyuki, Ito Taku, Honda Keiji, Takeda Takamori, Sonobe Akane, Aoki Natsuki, Bai Jing, Tsutsumi Takeshi: Cholesteatoma has an altered microbiota with a higher abundance of Staphylococcus species LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY. 2022.12; 7 (6): 2011-2019. ( PubMed , DOI )

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  3. 武内 寛明: 【新型コロナウイルス感染症(COVID-19)のすべて】病態と診断　SARS-CoV-2変異ウイルス　突然変異と選択から見えてくる進化の方向性 呼吸器ジャーナル. 2022.08; 70 (3): 338-343. ( 医中誌 )

  1. 北村 春樹, 多賀 佳, 助川 明香, 武内 寛明: 【新型コロナウイルス感染症(COVID-19)対策のこれから-ワクチンを中心に】COVID-19パンデミック下のSARS-CoV-2変異株の特徴および本邦市中流行株の遷移 臨床と微生物. 2021.11; 48 (6): 673-680. ( 医中誌 )

  2. Tanimoto Kousuke, Naruse Taeko K., Matano Tetsuro, Kimura Akinori: Development and evaluation of a rapid and cost-efficient NGS-based MHC class I genotyping method for macaques by using a prevalent short-read sequencer IMMUNOGENETICS. 2021.04; 73 (2): 175-186. ( PubMed , DOI )

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  1. 芳田 剛, Yao Weitong, 橋本 紗希, 武内 寛明, 山岡 昇司: HIV学術研究の今「ウイルスと宿主とのせめぎ合いから」(複製および病原性)　ウイルスの宿主適応メカニズム　宿主防御機構とのせめぎ合いと攻略能獲得まで 日本エイズ学会誌. 2020.11; 22 (4): 336. ( 医中誌 )

  2. 武内 寛明: HIV機能的治癒に向けた取り組みの現状　潜伏HIVリザーバー維持メカニズム　感染細胞レベルからその要因を解く　リザーバー特異的排除戦略によるHIV寛解をめざして 日本エイズ学会誌. 2020.11; 22 (4): 340. ( 医中誌 )

  1. Yao Weitong, 芳田 剛, 橋本 紗希, 武内 寛明, 山岡 昇司: HIV-1は抗ウイルスタンパク質ヒトBST-2を妨害する機能をどのように獲得したのか 日本エイズ学会誌. 2019.11; 21 (4): 464. ( 医中誌 )

  2. 堀口 諭吉, 直野 典彦, 坂本 修, 武内 寛明, 山岡 昇司, 谷口 正輝, 鷲尾 隆, 宮原 裕二: 分子認識とAIを活用したヒトインフルエンザウイルス粒子測定 日本バイオマテリアル学会大会予稿集. 2019.11; 41回 157. ( 医中誌 )

  3. Iwase Saori C., Miyazato Paola, Katsuya Hiroo, Islam Saiful, Yang Benjy Tan Jek, Ito Jumpei, Matsuo Misaki, Takeuchi Hiroaki, Ishida Takaomi, Matsuda Kouki, Maeda Kenji, Satou Yorifumi: HIV-1 DNA-capture-seq is a useful tool for the comprehensive characterization of HIV-1 provirus SCIENTIFIC REPORTS. 2019.08; 9 (1): 12326. ( PubMed , DOI )

  4. 谷本　幸介, 成瀬　妙子, 木村　彰方: ヒト以外の動物種を対象としたNGSによるMHCタイピング法 MHC. 2019.08; 26 (2): 115-123. ( DOI )

  5. 堀口 諭吉, 直野 典彦, 坂本 修, 武内 寛明, 山岡 昇司, 谷口 正輝, 鷲尾 隆, 宮原 裕二: 分子認識界面とAIテクノロジーを応用したウイルス粒子計測技術の創出 日本分析化学会講演要旨集. 2019.08; 68年会 241. ( 医中誌 )

  1. 合田 仁, 武内 寛明, 石田 尚臣: HIV感染に必要な細胞因子スクリーニングのためのジフテリア毒素とGFPのデュアルスプリットタンパク質の構築 日本エイズ学会誌. 2018.11; 20 (4): 515. ( 医中誌 )

  2. 武内 寛明, 合田 仁, 石田 尚臣, 佐藤 賢文, 岩瀬 早織, 山岡 昇司: HIV潜伏感染を制御する宿主因子の同定および解析 日本エイズ学会誌. 2018.11; 20 (4): 490. ( 医中誌 )

  3. 堀口 諭吉, 合田 達郎, 松元 亮, 武内 寛明, 山岡 昇司, 宮原 裕二: 細孔電気抵抗法を用いたヒトインフルエンザウイルスの特異的検出 日本分析化学会講演要旨集. 2018.08; 67年会 87. ( 医中誌 )

  4. 武内　寛明: 新規HIV-1感染制御宿主因子の同定およびその機能解明 日本エイズ学会誌. 2018.06; 20 117-123.

  5. 武内 寛明: 新規HIV-1感染制御宿主因子の同定およびその機能解明 日本エイズ学会誌. 2018.05; 20 (2): 117-123. ( 医中誌 )

  1. Hashimoto Saki, Yoshida Takeshi, Takeuchi Hiroaki, Yamaoka Shoji: HIV-1の祖先ウイルスが発現するVpuタンパク質の機能における種特異性とそのメカニズム 日本エイズ学会誌. 2017.11; 19 (4): 438. ( 医中誌 )

  2. 堀口 諭吉, 合田 達郎, 松元 亮, 武内 寛明, 山岡 昇司, 宮原 裕二: ウイルス認識ナノ粒子を用いた電気抵抗ナノパルス法によるウイルス計測 日本バイオマテリアル学会大会予稿集. 2017.11; 39回 253. ( 医中誌 )

  3. 武内 寛明: コア・サイエンス HIV-1コア・サイエンス　HIV-1コア(キャプシドコア)崩壊プロセスおよびHIV-1複合体コア(核)移行プロセスのさらなる展望 日本エイズ学会誌. 2017.11; 19 (4): 294. ( 医中誌 )

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