1. Noriko Funato, Arja Heliövaara, Cedric Boeckx: A regulatory variant impacting TBX1 expression contributes to basicranial morphology in Homo sapiens. Am J Hum Genet. 2024.04; in press ( PubMed , DOI )

  1. Noriko Funato*, Hiromi Yanagisawa: TBX1 targets the miR-200-ZEB2 axis to induce epithelial differentiation and inhibit stem cell properties. Scientific Reports. 2022.11; 12 (1): 20188. ( PubMed , DOI )

  2. Yuki Taga, Yu Iwasaki, Chisa Tometsuka, Noriko Funato, Yasutaka Shigemura, Masashi Kusubata, Kazunori Mizuno: Identification of a highly stable bioactive 3-hydroxyproline-containing tripeptide in human blood after collagen hydrolysate ingestion. NPJ Sci Food. 2022.06; 6 (1): 29. ( PubMed , DOI )

  3. Noriko Funato*: Craniofacial Phenotypes and Genetics of DiGeorge Syndrome. Journal Developmental Biology. 2022.05; 10 (2): 18. ( PubMed , DOI )

  1. Tometsuka C, Funato N, Mizuno K, Taga Y: Long-term intake of ginger protease-degraded collagen hydrolysate reduces blood lipid levels and adipocyte size in mice. Current research in food science. 2021.03; 4 175-181. ( PubMed , DOI )

  1. Noriko Funato*, Yuki Taga, Lindsay E Laurie, Chisa Tometsuka, Masashi Kusubata, Kiyoko Ogawa-Goto: The Transcription Factor HAND1 Is Involved in Cortical Bone Mass through the Regulation of Collagen Expression. Int J Mol Sci. 2020.11; 21 (22): 8638. ( PubMed , DOI )

  2. N Funato*, D Srivastava, S Shibata, H Yanagisawa: TBX1 Regulates Chondrocyte Maturation in the Spheno-occipital Synchondrosis. Journal of Dental Research. 2020.09; 99 (10): 1182-1191. ( PubMed , DOI )

  3. Funato N*: New Insights into Cranial Synchondrosis Development: A Mini Review. Frontiers in Cell and Developmental Biology. 2020.08; 8 (706): 1-9. ( PubMed , DOI )

  1. *Noriko Funato, Hiromi Yanagisawa: Deletion of the T-box transcription factor gene, Tbx1, in mice induces differential expression of genes associated with cleft palate in humans. Archives of Oral Biology. 2018.08; 95 149-155. ( PubMed , DOI )

  2. Yuki Taga, Masashi Kusubata, Kiyoko Ogawa-Goto, Shunji Hattori, and Noriko Funato: Collagen-derived X-Hyp-Gly-type tripeptides promote differentiation of MC3T3-E1 pre-osteoblasts Journal of Functional Foods. 2018.07; 46 456-462. ( DOI )

  1. *Noriko Funato, Masataka Nakamura: Identification of shared and unique gene families associated with oral clefts. Int J Oral Sci. 2017.06; 9 (2): 104-109. ( PubMed , DOI )

  1. *Noriko Funato, Hiroki Kokubo, Masataka Nakamura, Hiromi Yanagisawa, Yumiko Saga: Specification of jaw identity by the Hand2 transcription factor. Sci Rep. 2016.06; 6 28405. ( PubMed , DOI )

  2. *Noriko Funato, Hiroki Kokubo, Yumiko Saga: Transcriptomic analyses of Hand2 transgenic embryos. Genom Data. 2016.06; 9 60-62. ( PubMed , DOI )

  3. Lindsay E Laurie, Hiroki Kokubo, Masataka Nakamura, Yumiko Saga, *Noriko Funato: The transcription factor Hand1 is involved in Runx2-Ihh-regulated endochondral ossification PLoS ONE. 2016.02; 11 (2): e0150263. ( PubMed , DOI )

  4. Mariko Mizuguchi, Yuka Sasaki, Toshifumi Hara, Masaya Higuchi, Yuetsu Tanaka, Noriko Funato, Nobuyuki Tanaka, Masahiro Fujii, Masataka Nakamura: Induction of Cell Death in Growing Human T-Cells and Cell Survival in Resting Cells in Response to the Human T-Cell Leukemia Virus Type 1 Tax. PLoS ONE. 2016.02; 11 (2): e0148217. ( PubMed , DOI )

  1. Noriko Funato, Masataka Nakamura, Hiromi Yanagisawa: Molecular basis of cleft palates in mice. World J Biol Chem. 2015.08; 6 (3): 121-138. ( PubMed , DOI )

  2. Noriko Funato, Masataka Nakamura, James A. Richardson, Deepack Srivastava, Hiromi Yanagisawa.: Loss of Tbx1 induces bone phenotypes similar to cleidocranial dysplasia. Hum Mol Genet. 2015.01; 24 (2): 424-435. ( PubMed , DOI )

  1. Morita J, Nakamura M, Kobayashi Y, Deng C, Funato N, Moriyama K: Soluble form of FGFR2 with S252W partially prevents craniosynostosis of the apert mouse model. Dev. Dyn.. 2014.04; 243 (4): 560-567. ( PubMed , DOI )

  1. Terumi Mizukoshi, Hideyuki Komori, Mariko Mizuguchi, Hussein Abdelaziz, Toshifumi Hara, Masaya Higuchi, Yuetsu Tanaka, Yoshiro Ohara, Noriko Funato, Masahiro Fujii, Masataka Nakamura: Failure in activation of the canonical NF-κB pathway by human T-cell leukemia virus type 1 Tax in non-hematopoietic cell lines. Virology. 2013.09; 443 (2): 226-235. ( PubMed , DOI )

  1. Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H: Tbx1 regulates oral epithelial adhesion and palatal development. Hum Mol Genet. 2012.03; 21 (11): 2524-2537. ( PubMed , DOI )

  1. Funato N, Chapman SL, McKee MD, Funato H, Morris JA, Shelton JM, Richardson JA, Yanagisawa H: Hand2 controls osteoblast differentiation in the branchial arch by inhibiting DNA binding of Runx2. Development. 2009.02; 136 (4): 615-625. ( PubMed , DOI )

  1. Barbosa AC, Funato N, Chapman S, McKee MD, Richardson JA, Olson EN, Yanagisawa H: Hand transcription factors cooperatively regulate development of the distal midline mesenchyme. Dev Biol. 2007.10; 310 (1): 154-168. ( PubMed , DOI )

  2. Ohkuma M, Funato N, Higashihori N, Murakami M, Ohyama K, Nakamura M: Unique CCT repeats mediate transcription of the TWIST1 gene in mesenchymal cell lines. Biochem Biophys Res Commun. 2007.01; 352 (4): 925-931. ( PubMed , DOI )

  1. Funato N, Twigg SR, Higashihori N, Ohyama K, Wall SA, Wilkie AO, Nakamura M: Functional analysis of natural mutations in two TWIST protein motifs. Hum Mutat. 2005.06; 25 (6): 550-556. ( PubMed , DOI )

  2. Funato N, Nohtomi-Ohyama J, Ohyama K: Monozygotic twins concordant for Crouzon syndrome. Am J Med Genet A. 2005.03; 133A (2): 225. ( PubMed , DOI )

  1. Takahashi E, Funato N, Higashihori N, Hata Y, Gridley T, Nakamura M: Snail regulates p21(WAF/CIP1) expression in cooperation with E2A and Twist. Biochem Biophys Res Commun. 2004.12; 325 (4): 1136-1144. ( PubMed , DOI )

  1. Kanda T, Funato N, Baba Y, Kuroda T: Evidence for fibroblast growth factor receptors in myofibroblasts during palatal mucoperiosteal repair. Arch Oral Biol. 2003.03; 48 (3): 213-221. ( PubMed )

  2. Funato N, Ohyama K, Kuroda T, Nakamura M: Basic helix-loop-helix transcription factor epicardin/capsulin/Pod-1 suppresses differentiation by negative regulation of transcription. J Biol Chem. 2003.02; 278 (9): 7486-7493. ( PubMed , DOI )

  1. Funato N, Ohtani K, Ohyama K, Kuroda T, Nakamura M: Common regulation of growth arrest and differentiation of osteoblasts by helix-loop-helix factors. Mol Cell Biol. 2001.11; 21 (21): 7416-7428. ( PubMed , DOI )

  2. Hatai T, Yokozeki M, Funato N, Baba Y, Moriyama K, Ichijo H, Kuroda T: Apoptosis of periodontal ligament cells induced by mechanical stress during tooth movement. Oral Dis. 2001.09; 7 (5): 287-290. ( PubMed )

  1. Funato N, Moriyama K, Baba Y, Kuroda T: Evidence for apoptosis induction in myofibroblasts during palatal mucoperiosteal repair. J Dent Res. 1999.09; 78 (9): 1511-1517. ( PubMed )

  1. Funato N, Moriyama K, Saitoh M, Baba Y, Ichijo H, Kuroda T: Evidence for apoptosis signal-regulating kinase 1 in the regenerating palatal epithelium upon acute injury. Lab Invest. 1998.04; 78 (4): 477-483. ( PubMed )

  1. Funato N, Moriyama K, Shimokawa H, Kuroda T: Basic fibroblast growth factor induces apoptosis in myofibroblastic cells isolated from rat palatal mucosa. Biochem Biophys Res Commun. 1997.11; 240 (1): 21-26. ( PubMed , DOI )

  1. Funato N, Ohyama K, Nakamura M: Basic helix-loop-helix (bHLH) factors in osteoblast differentiation. J Oral Biosciences. 2002.09;

To the head of this page.▲