1. Yuki Nakao, Yutaro Mori, Makiko Mori, Shintaro Mandai, Tamami Fujiki, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Eisei Sohara, Shinichi Uchida. Tubuloids on Primary Human Renal Tubular Epithelial Cells (hRTECs) Recapitulates Cisplatin-Induced Kidney Injury. Kidney Week 2023 2023.11.04 Philadelphia

  2. Takuya Fujimaru, Takayasu Mori, Motoko Chiga, Shintaro Mandai, Yu Hara, Tamami Fujiki, Hiroaki Kikuchi, Yutaro Mori, Fumiaki Ando, Koichiro Susa, Soichiro Iimori, Shotaro Naito, Shinichi Uchida, Eisei Sohara.. Monoallelic IFT140 Pathogenic Variants in Adult Polycystic Kidney Disease Patients Without Family History.. ASN Kidney Week 2023 2023.11.04 Philadelphia

  3. Amrendra K. Ajay, Yutaro Mori, Venkata Sabbisetti, Joseph V. Bonventre. Screening for Small-Molecule Inhibitor for KIM-1 and Its Functional Validation in Kidney Fibrosis. Kidney Week 2023 2023.11.04

  4. Takayasu Mori, Takuya Fujimaru, Chunyu Liu, Karynne Patterson, Kohei Yamamoto, Takefumi Suzuki, Motoko Chiga, Shintaro Mandai, Fumiaki Ando, Yutaro Mori, Koichiro Susa, Yue-Qiu Tan, Feng Zhang, Shinichi Uchida, Eisei Sohara. Discovery of a Novel Candidate Gene Implicated in X-Linked Polycystic Kidney Disease. Kidney Week 2023 2023.11.04

  5. Yu Hara, Fumiaki Ando, Hideki Yanagawa, Soichiro Suzuki, Tamami Fujiki, Shintaro Mandai, Yutaro Mori, Koichiro Susa, Takayasu Mori, Eisei Sohara, Shinichi Uchida.. LRBA Signalosomes Activate Vasopressin-Induced AQP2 Trafficking at Recycling Endosomes.. ASN Kidney Week 2023 2023.11.03 Philadelphia

  6. Shunsuke Inaba, Shintaro Mandai, Yuta Nakano, Hisazumi Matsuki, Tamami Fujiki, Yutaro Mori, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Soichiro Iimori, Shotaro Naito, Eisei Sohara, Shinichi Uchida.. The Transcriptomic Landscape of microRNAs Encapsulated in Circulating Extracellular Vesicles and CKD Progression in Japanese Adults.. ASN Kidney Week 2023 2023.11.03 Philadelphia

  7. Makiko Mori, Yutaro Mori, Corby Fink, Takaharu Ichimura, Keisuke Sako, Yuki Nakao, Astrid Weins, Shinichi Uchida, Joseph V. Bonventre. Kidney Injury Molecule-1 Is an Independent Receptor from ACE2 for SARS-CoV-2 in Lung and Kidney. Kidney Week 2023 2023.11.03 Philadelphia

  8. Yuta Nakano, Shintaro Mandai, Shotaro Naito, Tamami Fujiki, Yutaro Mori, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Soichiro Iimori, Eisei Sohara, Shinichi Uchida.. Association Among Bone Mass, Muscle Mass and Strength, Mortality, and CKD Progression in Older Adults.. ASN Kidney Week 2023 2023.11.02 Philadelphia

  9. Takayasu Mori, Takuya Fujimaru, Chunyu Liu, Karynne Patterson, Kohei Yamamoto, Takefumi Suzuki, Motoko Chiga, Shintaro Mandai, Fumiaki Ando, Yutaro Mori, Koichiro Susa, University of Washington Center for Rare Disease Research, Yue-Qiu Tan, Feng Zhang, Shinichi Uchida, Eisei Sohara. Discovery of a Novel Candidate Gene Implicated in X-Linked Polycystic Kidney Disease. ASN Kidney Week 2023 2023.11 Philadelphia

  10. Takayasu Mori, Takuya Fujimaru, Chunyu Liu, Karynne Patterson, Kohei Yamamoto, Takefumi Suzuki, Motoko Chiga, Danny E Miller, Miranda PG Zalusky, Shintaro Mandai, Fumiaki Ando, Yutaro Mori, Hiroaki Kikuchi, Koichiro Susa, University of Washington Center for Rare Disease Research, Jessica X. Chong, Michael J. Bamshad, Yue-Qiu Tan, Feng Zhang, Shinichi Uchida, Eisei Sohara. Discovery of a novel responsible gene implicated in X-linked polycystic kidney disease. 第7回文京腎研究会 2023.10.19 東京/Web

  11. Hara Yu. LRBA is essential for urinary concentration and body water homeostasis. 第66回日本腎臓学会総会 2023.06.11 横浜

  12. Makiko Mori, Yutaro Mori, Takaharu Ichimura, Keisuke Sako, Shinichi Uchida, Joseph V. Bonventre. Kidney Injury Molecule-1 (KIM-1) is a Receptor for SARS-CoV-2 in Lung and Kidney. 第66回日本腎臓学会学術総会 2023.06.10 横浜

  13. Hisazumi Matsuki, Shintaro Mandai, Takaaki Koide, Naohiro Takahashi, Tomoki Yanagi, Tamami Fujiki, Yutaro Mori, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Soichiro Iimori, Eisei Sohara, Shinichi Uchida. A brain proteomic signature of chronic kidney disease uncovers blood-brain barrier breakdown via urea-activated matrix metalloproteinase-2. 第66回日本腎臓学会学術総会 2023.06.09 横浜

  14. Yuta Nakano, Shintaro Mandai, Shotaro Naito, Tamami Fujiki, Yutaro Mori, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Soichiro Iimori, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida. Impact of Osteosarcopenia on Mortality and CKD Progression: A Prospective Observational Cohort Study. 第66回日本腎臓学会学術総会 2023.06.09 横浜

  15. Shintaro Mandai. Signature Analyses for Circulating Extracellular Vesicle-Propagated MicroRNAs Reveal VEGFA as a Key Molecule for Vascular Calcification in Chronic Kidney Disease. The 66th Annual Meeting of the Japanese Society of Nephrology 2023.06.09 横浜

  16. Mandai Shintaro, Koide Takaaki, Kitaoka Reo, Matsuki Hisazumi, Suzuki Soichiro, Fujiki Tamami, Ando Fumiaki, Mori Takayasu, Susa Koichiro, Iimori Soichiro, Naito Shotaro, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi. Signature Analyses for Circulating Extracellular Vesicle-Propagated MicroRNAs Reveal VEGFA as a Key Molecule for Vascular Calcification in Chronic Kidney Disease. 第66回日本腎臓学会学術集会総会 2023.06

  17. Matsuki Hisazumi, Mandai Shintaro, Koide Takaaki, Takahashi Naohiro, Yanagi Tomoki, Fujiki Tamami, Mori Yutaro, Ando Fumiaki, Mori Takayasu, Susa Koichiro, Iimori Soichiro, Sohara Eisei, Uchida Shinichi. A brain proteomic signature of chronic kidney disease uncovers blood-brain barrier breakdown via urea-activated matrix metalloproteinase-2. 第66回日本腎臓学会学術集会総会 2023.06

  18. Nakano Yuta, Mandai Shintaro, Naito Shotaro, Fujiki Tamami, Mori Yutaro, Ando Fumiaki, Mori Takayasu, Susa Koichiro, Iimori Soichiro, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi. Impact of Osteosarcopenia on Mortality and CKD Progression: A Prospective Observational Cohort Study. 第66回日本腎臓学会学術集会総会 2023.06

  1. Underlying Genetic Causes of Adult Patients With ESKD Undergoing Hemodialysis Therapy. 2022.11.05

  2. Kidney Injury Molecule-1 (KIM-1) Shapes the Kidney Immune Microenvironment via Lymphotoxin Beta Receptor (LTbR) Signaling. 2022.11.04

  3. Small Molecule Screening Identifies TW-37 as a KIM-1 Inhibitor and Potential Anti-Fibrotic Molecule. 2022.11.03

  4. Navin R. Gupta, Takuya Matsumoto, Ken Hiratsuka, Pierre Galichon, Tomoya Miyoshi, Koichiro Susa, Narihito Tatsumoto, Michifumi Yamashita, Ryuji Morizane.. Modeling Kidney Injury and Repair in Kidney Organoids Reveals an Intrinsic Repair Mechanism.. The 54th Annual Meeting of American Society of Nephrology 2022.11 WEB

  5. Suzuki S, Ando F, Hara Y, Fujiki T, Mandai S, Susa K, Mori T, Sohara E, Rai T, Uchida S. ZNF185 Prevents Stress Fiber Formation Through the Inhibition of RhoA in Endothelial Cells. ASN Kidney Week 2022 2022.11 Orland

  6. Kanamori T, Udagawa T, Murakoshi M, Adachi E, Okutsu M, Mori T, Sohara E, Uchida S. A Missense Mutation in Zinc Finger 4 of WT1 Might Lead to Focal Segmental Glomerular Sclerosis due to Its Mislocalization and Downstream Dysregulation. ASN Kidney Week 2022 2022.11 Orland

  7. Hara Y, Ando F, Oikawa D, Ichimura K, Fujiki T, Mandai S, Mori T, Susa K, Sohara E, Rai T, Tokunaga F, Uchida S. LRBA Is Essential for Urinary Concentration and Body Water Homeostasis. ASN Kidney Week 2022 2022.11 Orland

  8. Yanagi T, Kikuchi H, Takeuchi K, Susa K, Takahashi N, Nakano Y, Ando F, Mandai S, Mori T, Honda S, Torii S, Shimizu S, Rai T, Uchida S, Sohara E. ULK1-Regulated AMP Sensing Mechanism by AMPK Is Disrupted in CKD. ASN Kidney Week 2022 2022.11 Orland

  9. Hara Y, Ando F, Oikawa D, Ichimura K, Fujiki T, Mandai S, Mori T, Susa K, Sohara E, Rai T, Tokunaga F, Uchida S. LRBA Is Essential for Urinary Concentration and Body Water Homeostasis. ASN Kidney Week 2022 2022.11

  10. Kanamori T, Udagawa T, Murakoshi M, Adachi E, Okutsu M, Mori T, Sohara E, Uchida S. A Missense Mutation in Zinc Finger 4 of WT1 Might Lead to Focal Segmental Glomerular Sclerosis due to Its Mislocalization and Downstream Dysregulation. ASN Kidney Week 2022 2022.11 Orland

  11. Suzuki S, Ando F, Hara Y, Fujiki T, Mandai S, Susa K, Mori T, Sohara E, Rai T, Uchida S. ZNF185 Prevents Stress Fiber Formation Through the Inhibition of RhoA in Endothelial Cells. ASN Kidney Week 2022 2022.11

  12. Yanagi T, Kikuchi H, Takeuchi K, Susa K, Takahashi N, Nakano Y, Ando F, Mandai S, Mori T, Honda S, Torii S, Shimizu S, Rai T, Uchida S, Sohara E. ULK1-Regulated AMP Sensing Mechanism by AMPK Is Disrupted in CKD. ASN Kidney Week 2022 2022.11 Orland

  13. Fujimaru T, Mori T, Chiga M, Mandai S, Ando F, Mori Y, Susa K, Nakano Y, Shoji T, Fukudome Y, Inaba N, Kitamura K, Nakanishi T, Kimura T, Tamura T, Ozawa K, Uchida S, Sohara E. Underlying Genetic Causes of Adult Patients With ESKD Undergoing Hemodialysis Therapy. ASN Kidney Week 2022 2022.11 Orland

  14. MORI Yutaro. KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease. 第26回日本心血管内分泌代謝学会学術総会 2022.10.12 京都

  15. Ando F. Identification of therapeutic targets for congenital nephrogenic diabetes insipidus. BENZON SYMPOSIUM No.66 2022.09

  16. Eisei SOHARA. Understanding Cystic Kidney Disease by Comprehensive Genetic Panel Test 〜Emerging Role of Clinical Genetics in CKD〜 . JSN/ASN Joint Symposium, The 65th Annual Meeting of the Japanese Society of Nephrology 2022.06.11 Kobe, Japan

  17. Fumiaki Ando. Identification of an A-Kinase Anchor Protein Essential for Urinary Concentration. The 42nd Annual Meeting of the Korean Society of Nephrology. Basic Science Symposium. 2022.05.27

  18. Nakano Yuta, Mandai Shintaro, Genma Taku, Akagi Yuichiro, Fujiki Tamami, Ando Fumiaki, Susa Koichiro, Mori Takayasu, Iimori Soichiro, Naito Shotaro, Sohara Eisei, Uchida Shinichi, Fushimi Kiyohide, Rai Tatemitsu. 大規模手術における周術期急性透析の必要性に関連する死亡率リスクの全国調査(Nationwide Mortality Risk Associated with Perioperative Acute Dialysis Requirement in Major Surgeries). 日本腎臓学会誌 2022.05.01

  1. Shimohata Homare, Miyake Yusuke, Yoshida Yu, Usui Joichi, Mori Takayasu, Sohara Eisei, Uchida Shinichi, Hirayama Kouichi, Kobayashi Masaki. 電顕所見でミエリン像を認めたLMX1B関連腎症(LMX1B-associated nephropathy that showed myelin figures on electron microscopy). CEN Case Reports 2021.11.01

  2. Nanamatsu A, Mori T, Ando F, Furusho T, Mandai S, Susa K, Sohara E, Rai T, Uchida S. Vasopressin induces urinary uromodulin secretion by activating protein kinase A. ASN Kidney Week 2021 2021.11 San Diego/web

  3. Oe Yuji, Mishima Eikan, Mori Takayasu, Okamoto Koji, Honkura Yohei, Nagasawa Tasuku, Yoshida Mai, Sato Hiroshi, Suzuki Jun, Ikeda Ryoukichi, Sohara Eisei, Uchida Shinichi, Katori Yukio, Miyazaki Mariko. LMX1Bの新規変異(p.Pro219Ala)はアルポート症候群様表現型の巣状分節性糸球体硬化症を引き起こす(A Novel Mutation in LMX1B(p.Pro219Ala) Causes Focal Segmental Glomerulosclerosis with Alport Syndrome-like Phenotype). Internal Medicine 2021.09.01

  4. Shintaro Mandai, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Soichiro Iimori, Shotaro Naito, Eisei Sohara, Shinichi Uchida, Kiyohide Fushimi, Tatemitsu Rai. Burden of Kidney Disease on Discrepancy between Reasons for Admission and Death:A Nationwide Cohort Study of Japanese Adults. 2021.06.20

  5. Yutaro Mori, Seiji Kishi, Takaharu Ichimura, Joseph V. Bonventre. Kidney Injury Molecule-1 (KIM-1)-mediated Proximal Tubular (PT) Uptake of Fatty Acid (FA)-Albumin Leads to Progressive Diabetic Kidney Disease (DKD). 第64回日本腎臓学会学術総会 2021.06.18 横浜、オンライン

  6. Mandai Shintaro, Ando Fumiaki, Mori Takayasu, Susa Koichiro, Iimori Soichiro, Naito Shotaro, Sohara Eisei, Uchida Shinichi, Fushimi Kiyohide, Rai Tatemitsu. 腎臓病に関する入院理由と死因の不一致がもたらす負荷　日本人成人に関する全国調査(Burden of Kidney Disease on Discrepancy between Reasons for Admission and Death:A Nationwide Cohort Study of Japanese Adults). 日本腎臓学会誌 2021.06.01

  7. Mandai Shintaro, Ando Fumiaki, Mori Takayasu, Susa Koichiro, Iimori Soichiro, Naito Shotaro, Sohara Eisei, Uchida Shinichi, Fushimi Kiyohide, Rai Tatemitsu. 腎臓病に関する入院理由と死因の不一致がもたらす負荷　日本人成人に関する全国調査(Burden of Kidney Disease on Discrepancy between Reasons for Admission and Death:A Nationwide Cohort Study of Japanese Adults). 日本腎臓学会誌 2021.06.01

  8. Mandai Shintaro, Ando Fumiaki, Mori Takayasu, Susa Koichiro, Iimori Soichiro, Naito Shotaro, Sohara Eisei, Uchida Shinichi, Fushimi Kiyohide, Rai Tatemitsu. 腎臓病に関する入院理由と死因の不一致がもたらす負荷　日本人成人に関する全国調査(Burden of Kidney Disease on Discrepancy between Reasons for Admission and Death:A Nationwide Cohort Study of Japanese Adults). 第64回日本腎臓学会学術総会 2021.06

  9. 高橋直宏, 蘇原映誠, 有田誠, 菊池寛昭, 安藤史顕, 須佐紘一郎, 萬代新太郎, 森崇寧, 頼建光, 内田信一. Alox15 knock-outマウスは、腎臓におけるPGD2の増加を介してCKDの腎障害及び線維化を改善する. 第64回日本腎臓学会学術総会 2021.06

  10. Takahashi Naohiro, Kikuchi Hiroaki, Usui Ayaka, Furusho Taisuke, Fujimaru Takuya, Fujiki Tamami, Yanagi Tomoki, Matsuura Yoshiaki, Asano Kenichi, Yamamoto Kouhei, Ando Fumiaki, Susa Koichiro, Mandai Shintaro, Mori Takayasu, Rai Tatemitsu, Uchida Shinichi, Arita Makoto, Sohara Eisei. ALOX15の欠損は腎臓でのPGD2の増加により腎機能障害を改善し線維化を抑制する(Deletion of Alox15 improves kidney dysfunction and inhibits fibrosis by increased PGD2 in the kidney). Clinical and Experimental Nephrology 2021.05.01

  11. Iijima Takashi, Mori Takayasu, Sohara Eisei, Suwabe Tatsuya, Hoshino Junichi, Ubara Yoshifumi. 血液透析下で持続性多渇症を呈したAVPR2変異による先天性腎性尿崩症の1例(A patient with congenital nephrogenic diabetes insipidus due to AVPR2 mutation complicated by persisting polydipsia under hemodialysis treatment). CEN Case Reports 2021.05.01

  12. Takedani Kai, Notsu Masakazu, Koike Sayo, Yamauchi Mika, Mori Takayasu, Sohara Eisei, Yamauchi Asuka, Yoshikane Kaori, Ito Takafumi, Kanasaki Keizo. ビタミンD欠損症を伴った非定型腎尿細管性アシドーシスによる骨軟化症　症例報告(Osteomalacia caused by atypical renal tubular acidosis with vitamin D deficiency: a case report). CEN Case Reports 2021.05.01

  13. Yutaro Mori. KIM-1/TIM-1 is a Receptor/Attachment Factor for SARS-CoV-2 in Lung and Kidney. Basic Science Research Seminar, Renal Division, Brigham and Women's Hospital, Harvard Medical School 2021.02.03 ボストン

  1. Ando F, Uchida S. Development of Novel Therapeutic Strategies for Congenital NDI and Other PKA-Related Diseases. The 43th Annual Meeting of the Molecular Biology Society of Japan (MBSJ2020) 2020.12.03 web

  2. Shintaro Mandai. WNK1 kinase: a novel potential player in skeletal muscle hypertrophy and sarcopenia induced by chronic kidney disease. The 43th Annual Meeting of the Molecular Biology Society of Japan (MBSJ2020) 2020.12.03 web

  3. Ando F, Uchida S. Development of Novel Therapeutic Strategies for Congenital NDI and Other PKA-Related Diseases. 第43回⽇本分⼦⽣物学会年会 2020.12 web

  4. Umene Ryusuke, Kitamura Mineaki, Arai Hideyuki, Matsumura Kazuki, Ishimaru Yuka, Maeda Kanenori, Uramatsu Tadashi, Obata Yoko, Mori Takayasu, Sohara Eisei, Uchida Shinichi, Nishino Tomoya. 腎機能障害により悪化した2遺伝子性の塩類喪失性尿細管機能異常症を呈したBartter症候群(Bartter syndrome representing digenic-based salt-losing tubulopathies presumably accelerated by renal insufficiency). CEN Case Reports 2020.11.01

  5. Yutaro Mori, Amrendra K. Ajay, Ankit B. Patel, Andrew M. Siedlecki, Seiji Kishi, Takaharu Ichimura, Joseph V. Bonventre. Inhibition of KIM-1-Mediated Fatty Acid Uptake by a Novel Inhibitor Attenuates Pro-Fibrotic Responses in Multiple Models of Human Primary Kidney Epithelial Cells Including Kidney Tubuloids. Kidney Week 2020 (The 53rd Annual Meeting of the American Society of Nephrology) 2020.10.22 オンライン開催

  6. Takaharu Ichimura, Mahmoud L. Nasr, Samuel Mon-Wei Yu, Yutaro Mori, Joseph V. Bonventre. Kidney Injury Molecule 1 Is a Receptor for SARS-CoV-2. Kidney Week 2020 (The 53rd Annual Meeting of the American Society of Nephrology) 2020.10.22 オンライン開催

  7. Ando F. 【大島賞受賞記念講演】Identification of Therapeutic Targets for Congenital Nephrogenic Diabetes Insipidus. 第63回日本腎臓学会学術総会 2020.08.18 横浜, web

  8. Mishima Eikan, Mori Takayasu, Nakajima Yoko, Toyohara Takafumi, Kikuchi Koichi, Oikawa Yoshitsugu, Matsuhashi Tetsuro, Maeda Yasuhiro, Suzuki Takehiro, Kudo Masataka, Ito Sadayoshi, Sohara Eisei, Uchida Shinichi, Abe Takaaki. 家族性若年性痛風を呈したHPRT1の新規p.V35M変異を伴うHPRT関連高尿酸血症(HPRT-related hyperuricemia with a novel p.V35M mutation in HPRT1 presenting familial juvenile gout). CEN Case Reports 2020.08.01

  9. 安藤 史顕. AQP2制御の分子メカニズムの同定と先天性腎性尿崩症の治療薬開発(Identification of Molecular Mechanisms for AQP2 Regulation and Development of Therapeutic Drugs for Congenital Nephrogenic Diabetes Insipidus). 日本腎臓学会誌 2020.07.01

  10. Adya Saran Sinha , Wang Tianying, Hosoi Yasushi, Sohara Eisei, Akita Tenpei, Uchida Shinichi, Fukuda Atsuo. WNK3キナーゼはマウス内側前頭前野のV層錐体神経細胞における内向き整流と細胞内クロライドを調節することで興奮を維持する(WNK3 kinase maintains basal excitability by regulating inward rectification and intracellular chloride in layer V pyramidal neurons of mouse medial prefrontal cortex). The Journal of Physiological Sciences 2020.03.01

  11. Adya Saran Sinha , Wang Tianying, Hosoi Yasushi, Sohara Eisei, Akita Tenpei, Uchida Shinichi, Fukuda Atsuo. WNK3キナーゼはマウス内側前頭前野のV層錐体神経細胞における内向き整流と細胞内クロライドを調節することで興奮を維持する(WNK3 kinase maintains basal excitability by regulating inward rectification and intracellular chloride in layer V pyramidal neurons of mouse medial prefrontal cortex). The Journal of Physiological Sciences 2020.03.01

  12. Sohara Eisei. WNK signal in salt-sensitive hypertension. The 9th CKD Frontier Meetings 2020.02.15 Nagoya, Japan

  13. Furusho T, Sohara E, Mandai S, Kikuchi H, Takahashi N, Fujimaru T, Hashimoto H, Arai Y, Ando F, Zeniya M, Mori T, Susa K, Isobe K, Nomura N, Yamamoto K, Okado T, Rai T, Uchida S. Renal TNFα activates the WNK phosphorylation cascade and contributes to salt-sensitive hypertension in chronic kidney disease. 第9回CKD frontier meeting 2020.02 名古屋

  1. Sohara Eisei. Failure to sense energy depletion in chronic kidney disease.. The 42nd Annual Meeting of the Molecular Biology Society of Japan 2019.12.04 Kobe, Japan

  2. Mori Y, Ichimura T, Patel AB, Siedlecki AM, Bonventre JV. Protocol to Make Renal Tubuloids from Human Kidneys. The 52nd Annual Meeting of the American Society of Nephrology. 2019.11.09 Washington, DC

  3. Li J, Chang JH, Suzuki T, Yang C, Mori Y, Yamashita M, Sabbisetti V, Ichimura T, Bonventre JV. Altered Citrate Metabolism Leads to Maladaptive Repair After Tubular Injury and Facilitates Kidney Fibrosis in Diabetic Nephropathy. The 52nd Annual Meeting of the American Society of Nephrology. 2019.11.09 Washington, DC

  4. Fujimaru T, Mori T, Nagata M, Mandai S, Chiga M, Kikuchi H, Ando F, Mori Y, Susa K, Isobe K, Iimori S, Nomura N, Naito S, Okado T, Rai T, Uchida S, Sohara E. Tubular Basement Membrane Duplication and Cell Interposition Are Distinctive Histological Findings in the Adult Patients Genetically Diagnosed with Nephronophthisis-Related Ciliopathies. The 52nd Annual Meeting of the American Society of Nephrology. 2019.11.08 Washington, DC

  5. Mori Y, Ajay AK, Chang JH, Zhao H, Kishi S, Li J, Galichon P, Brooks CR, Xiao S, Sabbisetti V, Palmer S, Henderson JM, Ichimura T, Bonventre JV. Proximal Tubular Uptake of Free Fatty Acid (FFA) by Kidney Injury Molecule-1 (KIM-1) Mediates Tubulointerstitial Damage in Diabetic Kidney Disease (DKD), Which Is Attenuated by a Novel Inhibitor. The 52nd Annual Meeting of the American Society of Nephrology. 2019.11.08 Washington, DC

  6. Tamami Fujiki, Fumiaki Ando, Shintaro Mandai, Kiyoshi Isobe, Takayasu Mori, Koichiro Susa, Naohiro Nomura, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida.. Tolvaptan and Bardoxolone Methyl Synergistically Activate the Nrf2/ HO-1 Pathway.. The 52nd Annual Meeting of American Society of Nephrology. 2019.11.08 Washington DC

  7. Koichiro Susa, Akitoshi Tamura, Pierre Galichon, Navin R. Gupta, Takuya Matsumoto, Tomoya Miyoshi, Venkata Sabbisetti, Joseph V. Bonventre, Ryuji Morizane.. A Drug-Specific Nephrotoxicity Prediction System Using Kidney Organoids.. The 52nd Annual Meeting of American Society of Nephrology. 2019.11.08 Washington DC

  8. Navin R. Gupta, Ken Hiratsuka, Tomoya Miyoshi, Koichiro Susa, Narihito Tatsumoto, Michifumi Yamashita, Ryuji Morizane.. Fibrotic Kidney Organoids and Human CKD Samples Demonstrate Loss of Homologous Recombination as a Critical Mediator of Maladaptive Repair. The 52nd Annual Meeting of American Society of Nephrology.. The 52nd Annual Meeting of American Society of Nephrology. 2019.11.08 Washington DC

  9. Naohiro Takahashi, Hiroaki Kikuchi, Makoto Arita, Fumiaki Ando, Shintaro Mandai, Kiyoshi Isobe, Koichiro Susa, Takayasu Mori, Naohiro Nomura, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara.. 12/15-Lipoxygenase Knockout Mice Exhibit a Resistance to Kidney Damage in CKD.. The 52nd Annual Meeting of American Society of Nephrology. 2019.11.08 Washington DC

  10. Takuya Fujimaru, Takayasu Mori, Michio Nagata, Shintaro Mandai, Motoko Chiga, Hiroaki Kikuchi, Fumiaki Ando, Yutaro Mori, Koichiro Susa, Kiyoshi Isobe, Soichiro Iimori, Naohiro Nomura, Shotaro Naito, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara.. Tubular Basement Membrane Duplication and Cell Interposition Are Distinctive Histological Findings in the Adult Patients Genetically Diagnosed with Nephronophthisis-Related Ciliopathies.. The 52nd Annual Meeting of American Society of Nephrology. 2019.11.08 Washington DC

  11. Taisuke Furusho, Shintaro Mandai, Hiroaki Kikuchi, Naohiro Takahashi, Takuya Fujimaru, Hiroko Hashimoto, Yohei Arai, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Kiyoshi Isobe, Naohiro Nomura, Tomokazu Okado, Tatemitsu Rai, Kohei Yamamoto, Shinichi Uchida, Eisei Sohara.. Renal TNF α Activates WNK Phosphorylation Cascade and Contributes to Salt-Sensitive Hypertension in CKD.. The 52nd Annual Meeting of American Society of Nephrology. 2019.11.08 Washington DC

  12. Yang M, Mori Y, Murakami N, Ichimura T, Bonventre JV. Kidney Injury Molecule-1 (KIM-1) Promotes Tertiary Lymphoid Tissue (TLT) Development in the Kidney Through LTaβ/LTβR Signaling. The 52nd Annual Meeting of the American Society of Nephrology. 2019.11.08 Washington, DC

  13. Fumiaki Ando, Naofumi Yui, Shintaro Mandai, Kiyoshi Isobe, Takayasu Mori, Koichiro Susa, Naohiro Nomura, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida.. Derivatives of FMP-API-1/27 Robustly Activate AQP2 Water Channels Independently of Vasopressin.. The 52nd Annual Meeting of American Society of Nephrology. 2019.11.07 Washington DC

  14. Chinen Takashi, Saeki Eiji, Mori Takayasu, Sohara Eisei, Uchida Shinichi, Akimoto Tetsu. Gitelman症候群の1例　離島における診療経験(A case of Gitelman syndrome: our experience with a patient treated in clinical practice on a local island). Journal of Rural Medicine 2019.11.01

  15. Mori T, Chiga M, Fujimaru T, Mandai S, Nanamatsu A, Sohara E, Rai T, Uchida S. More than half of patients clinically diagnosed as Gitelman syndrome in adulthood do not have causal mutations in known pathogenic genes. ASN Kidney Week 2019 2019.11

  16. Ando F, Yui N, Mandai S, Isobe K, Mori T, Susa K, Nomura N, Sohara E, Rai T, Uchida S. Derivatives of FMP-API-1/27 Robustly Activate AQP2 Water Channels Independently of Vasopressin. ASN Kidney Week 2019 2019.11

  17. MORI Yutaro. Proximal tubular uptake of free fatty acids (FFAs) by KIM-1 mediates tubulointerstitial disease in diabetic kidney disease. 次世代腎研究アカデミー2019学術集会 2019.08.17 東京

  18. Sohara Eisei. Failure to sense energy depletion in chronic kidney disease.. The 6th Diabetes Research Innovation Symposium 2019 2019.07.14 Kyoto

  19. Eisei Sohara. WNK signaling in salt-sensitive hypertension and electrolyte disorder. JSN/ASN Joint Symposium, The 62nd Annual Meeting of the Japanese Society of Nephrology 2019.06.21

  20. MORI Yutaro. The endocytotic uptake of free fatty acid by KIM-1 causes tubulointerstitial damage in diabetic kidney disease. Boston/Harvard Cell Death Initiative Seminar Series 2019.06.03 ボストン

  21. Sohara Eisei, Kikuchi Hiroaki, Uchida Shinichi. 腎機能の再生医療におけるNew Frontiers　慢性腎臓病におけるエネルギー状態感知不全(New Frontiers in Regenerative Medicine of Renal Function　Failure to sense energy depletion in chronic kidney disease). The Journal of Physiological Sciences 2019.06.01

  22. Sinha Adya Saran, Wang Tianying, Hosoi Yasushi, Sohara Eisei, Akita Tenpei, Uchida Shinichi, Fukuda Atsuo. WNK3キナーゼによる前頭前皮質におけるニューロン興奮性の調節メカニズム(Mechanisms underlying WNK3 kinase mediated regulation of neuronal excitability in prefrontal cortex). The Journal of Physiological Sciences 2019.06.01

  23. EISEI SOHARA. Whole exome data in rare disease gene discovery. International Society of Nephrology, World Congress of Nephrology 2019 2019.04.15 Melbourne, Australia

  24. EISEI SOHARA. Failure to sense energy depletion in chronic kidney disease. The 9th Federation of the Asian and Oceanian Physiological Societies Congress 2019.03.30 Kobe, Hyogo, Japan

  1. Yoshida Sayaka, Araki Yuya, Mori Takayasu, Sasaki Emi, Kasagi Yuri, Isobe Kiyoshi, Susa Koichiro, Inoue Yuichi, Bomont Pascale, Okado Tomokazu, Rai Tatemitsu, Uchida Shinichi, Sohara Eisei. KLHL3の発現低下はcullin 3のin vivoでの変異によって引き起こされる偽性低アルドステロン症II型の病態発生に関与する(Decreased KLHL3 expression is involved in the pathogenesis of pseudohypoaldosteronism type II caused by cullin 3 mutation in vivo). Clinical and Experimental Nephrology 2018.12.01

  2. Matsumoto Ayumi, Matsui Isao, Mori Takayasu, Sakaguchi Yusuke, Mizui Masayuki, Ueda Yoshiyasu, Takahashi Atsushi, Doi Yohei, Shimada Karin, Yamaguchi Satoshi, Kubota Keiichi, Hashimoto Nobuhiro, Oka Tatsufumi, Takabatake Yoshitsugu, Sohara Eisei, Hamano Takayuki, Uchida Shinichi, Isaka Yoshitaka. CLCN5遺伝子の新規イントロン変異を原因とするDent病を伴った重症骨軟化症(Severe Osteomalacia with Dent Disease Caused by a Novel Intronic Mutation of the CLCN5 gene). Internal Medicine 2018.12.01

  3. MORI Yutaro. KIM-1 - the New Therapeutic Target for Diabetic Nephropathy. Basic Science Research Seminar, Renal Division, Brigham and Women's Hospital, Harvard Medical School 2018.11.07 ボストン

  4. Fujiki T, Ando F, Isobe K, Mori T, Susa K, Nomura N, Sohara E, Rai T, Uchida S.. Tolvaptan Activates Nrf2/HO-1 Pathway Through PERK Phosphorylation. The 51st Annual Meeting of American Society of Nephrology 2018.10.27 San Diego

  5. Takahashi N, Kikuchi H, Ishihara T, Arita M, Furusho T, Ando F, Mori T, Isobe K, Susa K, Nomura N, Rai T, Uchida S, Sohara E.. Amelioration of Renal Fibrosis and Tubulointerstitial Damage in Fat-1 Transgenic CKD Mice by Compensation of Decreased Omega-3 Fatty Acids in the Kidney. The 51st Annual Meeting of American Society of Nephrology 2018.10.27 San Diego

  6. Fujimaru T, Mori T, Mandai S, Chiga M, Kikuchi H, Ando F, Mori Y, Susa K, Isobe K, Iimori S, Nomura N, Naito S, Okado T, Rai T, Nagatsuji K, Nagahama K, Mishima E, Mochizuki T, Sekine A, Hoshino J, Ubara Y, Uchida S, Sohara E.. Genomic Background of Adults with Suspected Ciliopathy on Renal Biopsy. The 51st Annual Meeting of American Society of Nephrology 2018.10.26 San Diego

  7. Gupta NR, Garcia E, Miyoshi T, Galichon P, Susa K, Walter LD, Epstein CB, Bonventre JV, Morizane R.. Human Kidney Organoids Model Tubular Injury and Maladaptive Repair with Interstitial Fibrosis In Vitro. The 51st Annual Meeting of American Society of Nephrology 2018.10.25 San Diego

  8. Tamura A, Susa K, Galichon P, Gupta NR, Miyoshi T, Sabbisetti V, Bonventre JV, Morizane R.. Kidney Organoids for Improved Prediction of Human Nephrotoxicity. The 51st Annual Meeting of American Society of Nephrology 2018.10.25 San Diego

  9. Mori Y, Chang JH, Mou S, Zhao H, Li J, Galichon P, Brooks CR, Xiao S, Sabbisetti VS, Palmer S, Kuchroo VK, Ichimura T, Bonventre JV. Proximal Tubular Uptake of Free Fatty Acid (FFA) by Kidney Injury Molecule-1 (KIM-1) Mediates Tubulointerstitial Disease in Diabetic Mice. The 51st Annual Meeting of the American Society of Nephrology. 2018.10.01 San Diego

  10. Fujimaru T, Mori T, Mandai S, Chiga M, Kikuchi H, Ando F, Mori Y, Susa K, Isobe K, Iimori S, Nomura N, Naito S, Okado T, Rai T, Nagatsuji K, Nagahama K, Mishima E, Mochizuki T, Sekine A, Hoshino J, Ubara Y, Uchida S, Sohara E. Genomic Background of Adults with Suspected Ciliopathy on Renal Biopsy. The 51st Annual Meeting of the American Society of Nephrology. 2018.10.01 San Diego

  11. Takahashi N, Kikuchi H, Ishihara T, Arita M, Furusho T, Ando F, Mori T, Isobe K, Susa K, Nomura N, Rai T, Uchida S, Sohara E.. Amelioration of Renal Fibrosis and Tubulointerstitial Damage in Fat-1 Transgenic CKD Mice by Compensation of Decreased Omega-3 Fatty Acids in the Kidney.. ASN Kidney Week 2018. 2018.10

  12. Sohara E, Mori T, Uchida S.. Development and application of comprehensive genetic testing system for major inherited kidney diseases, using next-generation sequencing with custom panels.. 20th Nephrology Symposium. 2018.10

  13. Shoda W, Nomura N, Ando F, Isobe K, Mori T, Susa K, Sohara E, Rai T, Uchida S.. Molecular mechanism of high-potassium induced Na-Cl cotransporter dephosphorylation.. ASN Kidney Week 2018. 2018.10

  14. Mandai S, Mori T, Nomura N, Furusho T, Arai Y, Kikuchi H, Sasaki E, Sohara E, Rai T, Uchida S.. WNK1 Regulates Skeletal Muscle Hypertrophy by Modulating Phosphorylation, Nuclear Localization, and Transcriptional Activity of FoxO4.. ASN Kidney Week 2018. 2018.10

  15. Hashimoto H, Nomura N, Shoda W, Isobe K, Kikuchi H, Yamamoto K, Fujimaru T, Ando F, Mori T, Okado T, Rai T, Uchida S, Sohara E.. Metformin has natriuretic effects through reduction of the sodium-chrolide cotransporter phosphorylation.. ASN Kidney Week 2018. 2018.10

  16. Furusho T, Sohara E, Mandai S, Kikuchi H, Ando F, Zeniya M, Mori T, Nomura N, Rai T, Uchida S.. WNK1-SPAK-NCC signaling cascade is involved in salt sensitive hypertension induced by aristolochic acid nephropathy.. ASN Kidney Week 2018. 2018.10

  17. 4. Fujimaru T, Mori T, Mandai S, Chiga M, Kikuchi H, Ando F, Mori Y, Susa K, Isobe K, Iimori S, Nomura N, Naito S, Okado T, Rai T, Nagatsuji K, Nagahama K, Mishima E, Mochizuki T, Sekine A, Hoshino J, Ubara Y, Uchida S, Sohara E.. Genomic Background of Adults with Suspected Ciliopathy on Renal Biopsy.. ASN Kidney Week 2018. 2018.10

  18. Fujiki T, Ando F, Isobe K, Mori T, Susa K, Nomura N, Sohara E, Rai T, Uchida S.. Tolvaptan activates Nrf2/HO-1 pathway through PERK phosphorylation.. ASN Kidney Week 2018. 2018.10

  19. Ando F, Yui N, Nomura N, Sohara E, Rai T, Sasaki S, Uchida S. AKAPs-PKA Disruptors Robustly Increase AQP2 Activity Independently of Vasopressin. The 52nd American Society of Nephrology, Kidney Week 2018 2018.10 San Diego

  20. Mori T. Genome big data will open the way of the future in nephrology.. 5th Next Generation Kidney Research Meeting, Tokyo 2018.08.18

  21. Soichiro Iimori. Evaluation and management of bone metabolism. 第63回日本透析医学会学術集会総会 2018.06.30 神戸

  22. Miyamoto Satoko, Ohkubo Atsushi, Seshima Hiroshi, Yamamoto Hiroko, Itagaki Ayako, Maeda Takuma, Kurashima Naoki, Mori Takayasu, Iimori Soichiro, Naito Shotaro, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi, Okado Tomokazu. 連続3日間の選択的血漿交換療法による自己抗体、免疫グロブリンおよび凝固因子の除去ダイナミクス(Removal Dynamics of Autoantibodies, Immunoglobulins, and Coagulation Factors by Selective Plasma Exchange on Three Consecutive Days). Therapeutic Apheresis and Dialysis 2018.06.01

  23. Mori Y, Chang JH, Mou S, Zhao H, Li J, Galichon P, Brooks CR, Xiao S, Woo HM, Sabbisetti VS, Palmer S, Henderson JM, Kuchroo VK, Ichimura T, Bonventre JV. Proximal tubular uptake of free fatty acid (FFA) by Kidney Injury Molecule-1 (KIM-1) mediates tubulointerstitial disease in diabetic nephropathy (DN). Cardio-Renal Research Symposium and Poster Session, Brigham and Women's Hospital 2018.05.01 Boston

  24. Saran Saran Adya, Hosoi Yasushi, Sohara Eisei, Mutoh Hiroki, Akita Tenpei, Uchida Shinichi, Fukuda Atsuo. WNK3 kinaseはマウス前頭前皮質のV層錐体神経細胞における内向き整流性potassium電流を制御する(WNK3 kinase regulates inwardly rectifying potassium current in layer V pyramidal neurons of the mouse prefrontal cortex). The Journal of Physiological Sciences 2018.03.01

  25. Uchida Shinichi. 生体システムの構築およびその破壊に関する統合的かつ理論的研究　慢性腎臓病に対するマルチオミックスなアプローチ(Integrative and theoretical research on the architecture of biological system and its disorder　Multi-omics approaches to chronic kidney disease). The Journal of Physiological Sciences 2018.03.01

  26. 5. Fujimaru T, Mori T, Sekine A, Mandai S, Chiga M, Kikuchi H, Ando F, Nomura N, Iimori S, Naito S, Okado T, Rai T, Hoshino J, Ubara Y, Uchida S, Sohara E.. Genomic diagnosis of adult polycystic kidney disease with no family history.. ISN Frontiers Meetings 2018. 2018.02

  1. Takayasu Mori, Motoko Chiga, Takuya Fujimaru, Shintaro Mandai, Shota Watanabe, Yasuhisa Nakamura, Takehiro Morishita, Osamu Uemura, Eri Imai, Shuzo Kaneko, Yusuke Tsukamoto, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida. We propose single heterozygous mutation in ATP6V0A4 as novel genetic cause of dRTA. The 50th Annual Meeting of the American Society of Nephrology 2017.11.02 New Orleans, LA.

  2. Shinichi Uchida. Translational researches in the field of water and electrolyte disorders. The annual meeting of the American Society of Nephrology 2017.11.02 New Orleans, USA

  3. Fujimaru T, Mori T, Sekine A, Mandai S, Chiga M, Kikuchi H, Ando F, Mori Y, Nomura N, Naito S, Okado T, Rai T, Hoshino J, Ubara Y, Uchida S, Sohara E. Genomic Background of Adult Polycystic Kidney Disease Patients without a Family History. The 50th Annual Meeting of the American Society of Nephrology 2017.11.01 New Orleans

  4. Mori Y, Galichon P, Brooks CR, Ichimura T, Bonventre JV. Kidney Injury Molecule-1 (KIM-1) Mediates the Proximal Tubule Uptake of Free Fatty Acids (FFA) Resulting in Mitochondrial Injury and the DNA Damage Response (DDR). The 50th Annual Meeting of the American Society of Nephrology 2017.11.01 New Orleans

  5. Sohara E.. Pseudohypoaldosteronism. 10th International Meeting of Pediatric Endocrinology 2017.09.14 Washington, USA

  6. Sohara Eisei. WNK kinase signalling to cation chloride transporters. Symposium, INTERNATIONAL UNION OF PHYSIOLOGICAL SCIENCE, 38th World Congress 2017.08.05 Rio de Janeiro, Brazil

  7. Takehara Eriko, Mandai Shintaro, Shikuma Satomi, Akita Wataru, Chiga Motoko, Mori Takayasu, Oda Takashi, Kuwahara Michio, Uchida Shinichi. 補体因子H変異を伴うモノクローナル免疫グロブリンG沈着症を合併する感染後増殖性糸球体腎炎(Post-infectious Proliferative Glomerulonephritis with Monoclonal Immunoglobulin G Deposits Associated with Complement Factor H Mutation). Internal Medicine 2017.04.01

  8. Soichiro Iimori, Shotaro Naito, Hidehiko Sato, Naohiro Nomura, Eisei Sohara, Tomokazu Okado, Shinichi Uchida, Tatemitsu Rai. Effects of proteinuria reduction on kidney function, mortality and cardiovascular risk in newly visiting CKD patients in Japan : the CKD-ROUTE study. The 6th CKD Frontier Meeting 2017.02.25 Nagoya, Japan

  9. Mori Takayasu, Hosomichi Kazuyoshi, Chiga Motoko, Mandai Shintaro, Nakaoka Hirofumi, Sohara Eisei, Okado Tomokazu, Rai Tatemitsu, Sasaki Sei, Inoue Ituro, Uchida Shinichi. カスタムパネルによる次世代シーケンシングを用いた主要な遺伝性腎疾患に対する包括的遺伝子検査手法(Comprehensive genetic testing approach for major inherited kidney diseases, using next-generation sequencing with a custom panel). Clinical and Experimental Nephrology 2017.02.01

  1. Daiei Takahashi, Takayasu Mori, Eisei Sohara, Motoko Chiga, Yuichi Inoue, Naohiro Nomura, Moko Zeniya, Tatemitsu Rai, and Shinichi Uchida. WNK4 regulates adipocyte differentiation in 3T3-L1 cells. The 47th Annual Meeting of American Society of Nephrology 2016.11.19 Chicago, IL.

  2. Takuya Fujimaru, Takayasu Mori, Shintaro Mandai, Motoko Chiga, Hiroaki Kikuchi, Fumiaki Ando, Yutaro Mori, Naohiro Nomura, Shotaro Naito, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara. Development of a Customized Diagnostic Panel for Targeted Exome Sequencing of Polycystic Kidney Diseases. Kidney Week 2016 2016.11.19 Chicago, IL

  3. Daiei Takahashi, Takayasu Mori, Eisei Sohara, Motoko Chiga, Yuichi Inoue, Naohiro Nomura, Moko Zeniya, Tatemitsu Rai, and Shinichi Uchida. WNK4 regulates adipocyte differentiation in 3T3-L1 cells. The 47th Annual Meeting of American Society of Nephrology 2016.11.19

  4. Takuya Fujimaru, Takayasu Mori, Shintaro Mandai, Motoko Chiga, Hiroaki Kikuchi, Fumiaki Ando, Yutaro Mori, Naohiro Nomura, Shotaro Naito, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara. Development of a Customized Diagnostic Panel for Targeted Exome Sequencing of Polycystic Kidney Diseases. Kidney Week 2016 2016.11.19

  5. Yohei Arai, Eiichiro Kanda, Soichiro Iimori, Shotaro Naito, Yumi Noda, Sei Sasaki, Eisei Sohara, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida. Low White Blood Cell Count Is Independently Associated with the Progression of Chronic Kidney Disease in the Elderly: The CKD-ROUTE Study. The 49th Annual Meeting of American Society of Nephrology 2016.11.18 Chicago

  6. Wakana Shoda, Naohiro Nomura, Fumiaki Ando, Yutaro Mori, Takayasu Mori, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida. Calcineurin Rapidly Dephosphorylates Sodium-ChlorideCotransporter in Response to High Potassium Intake. The 49th Annual Meeting of American Society of nephrology. 2016.11.18 Chicago

  7. Yuki Yoshizaki, Eisei Sohara, Takayasu Mori, Eriko Kikuchi, Daiei Takahashi, Moko Zeniya, Yuya Araki, Yutaro Mori, Fumiaki Ando, Tatemitsu Rai, Shinichi Uchida.. Drug Repositioning Screening for Keap1-Nrf2 Binding Inhibitors by Using Fluorescent Correlation Spectroscopy. The 49th Annual Meeting of American Society of Nephrology 2016.11.18 Chicago

  8. Emi Sasaki, Koichiro Susa, Takayasu Mori, Kiyoshi Isobe, Yuya Araki, Yuichi Inoue, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara. Generation and Analysis of KLHL3 Knockout Mice. The 49th Annual Meeting of American Society of nephrology 2016.11.18 Chicago

  9. Yohei Arai, Eiichiro Kanda, Soichiro Iimori, Shotaro Naito, Yumi Noda, Sei Sasaki, Eisei Sohara, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida. Low White Blood Cell Count Is Independently Associated with the Progression of Chronic Kidney Disease in the Elderly: The CKD-ROUTE Study. The 49th Annual Meeting of American Society of Nephrology 2016.11.18

  10. Yuki Yoshizaki, Eisei Sohara, Takayasu Mori, Eriko Kikuchi, Daiei Takahashi, Moko Zeniya, Yuya Araki, Yutaro Mori, Fumiaki Ando, Tatemitsu Rai, Shinichi Uchida.. Drug Repositioning Screening for Keap1-Nrf2 Binding Inhibitors by Using Fluorescent Correlation Spectroscopy. The 49th Annual Meeting of American Society of Nephrology 2016.11.18

  11. Emi Sasaki, Koichiro Susa, Takayasu Mori, Kiyoshi Isobe, Yuya Araki, Yuichi Inoue, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara. Generation and Analysis of KLHL3 Knockout Mice. The 49th Annual Meeting of American Society of nephrology 2016.11.18

  12. Wakana Shoda, Naohiro Nomura, Fumiaki Ando, Yutaro Mori, Takayasu Mori, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida. Calcineurin Rapidly Dephosphorylates Sodium-ChlorideCotransporter in Response to High Potassium Intake. The 49th Annual Meeting of American Society of nephrology. 2016.11.18

  13. Yutaro Mori, Shintaro Mandai, Takayasu Mori, Eisei Sohara, Tatematsu Rai, Shinichi Uchida. Generation of p62/SQSTM1 (p62) KO Cell Lines Using CRISPR/Cas9 -The Role of p62 on WNK1 Regulation by Changes of Extracellular Potassium Concentration-. The 49th Annual Meeting of the American Society of Nephrology 2016.11.17 Chicago

  14. Yutaro Mori, Shintaro Mandai, Takayasu Mori, Eisei Sohara, Tatematsu Rai, Shinichi Uchida. Generation of p62/SQSTM1 (p62) KO Cell Lines Using CRISPR/Cas9 -The Role of p62 on WNK1 Regulation by Changes of Extracellular Potassium Concentration-. The 49th Annual Meeting of the American Society of Nephrology 2016.11.17

  15. Hiroaki Kikuchi, Naohiro Nomura, Yoji Andrew Minamishima, Tatemitsu Rai, Shinichi Uchida and Eisei Sohara.. Targeted Metabolomic Analysis of Kidney from the Subtotal Nephrectomy Mouse Model of Chronic Kidney Disease. The 49th Annual Meeting of American Society of Nephrology. 2016.11.15 Chicago.

  16. Hiroaki Kikuchi, Naohiro Nomura, Yoji Andrew Minamishima, Tatemitsu Rai, Shinichi Uchida?and Eisei Sohara.. Targeted Metabolomic Analysis of Kidney from the Subtotal Nephrectomy Mouse Model of Chronic Kidney Disease. The 49th Annual Meeting of American Society of Nephrology. 2016.11.15

  17. Zeniya M, Mori T, Yui N, Nomura N, Chiga M, Sohara E, Rai T, Uchida S.. The proteasome inhibitor bortezomib attenuates renal fibrosis in mice.. The 49th Annual Meeting of American Society of Nephrology 2016.11.15

  18. Zeniya M, Mori T, Yui N, Nomura N, Chiga M, Sohara E, Rai T, Uchida S.. The proteasome inhibitor bortezomib attenuates renal fibrosis in mice.. The 49th Annual Meeting of American Society of Nephrology 2016.11.06 Chicago

  19. Wakana Shoda, Naohiro Nomura, Fumiaki Ando, Yutaro Mori, Takayasu Mori, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida. Calcineurin rapidly dephosphorylates sodium-chloride cotransporter in response to high potassium intake. 第26回御茶ノ水腎研究会 2016.10.27

  20. Mori T, Uchida S, Nickerson DA, Bamshad MJ, Chong JX and University of Washington Center for Mendelian Genomics.. Using maximum allele frequencies across populations greatly increases power for Mendelian gene discovery.. American Society of Human Genetics (ASHG) 2016 Annual Meeting. 2016.10.01 Vancouver

  21. Ando F, Sohara E, Yui N, Nomura N, Kikuchi E, Takahashi D, Mori T, Rai T, Sasaki S, and Uchida S.. Calcineurin is a target for the treatment of nephrogenic diabetes insipidus. . 3rd Next Generation Kidney Research Meeting. 2016.08 Tokyo

  1. Uchida Shinichi. The KLHL proteins, the WNKs and renal Na+ transport.. 8Th FAOPS (Federation of the Asian and Oceanian Physiological Societies) Congress 2015.11.23 Bangkok, Thailand

  2. Takehara Eriko, Mandai Shintaro, Uchida Shinichi . Reversal of Dialysis-Dependent Renal Failure and Nephrotic Syndrome after Conservative Therapy in an Adult with Proliferative Glomerulonephritis with C3-Dominant Deposition. 2015.11.07 San Diego, USA

  3. Wakana Shoda, Naofumi Yui, Shotaro Naito, Soichiro Iimori, Koichiro Susa, Takayasu Mori, Naohiro Nomura, Eisei Sohara, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida. Sunitinib-Induced Nephrotic Syndrome and Acute Kidney Injury in a Malignant Insulinoma Patient: A Case Report. The 48th Annual Meeting of American Society of Nephrology 2015.11.07 San Diego, USA

  4. Shotaro Naito, Soichiro Iimori, Eisei Sohara, Tomokazu Okado, Sei Sasaki, Shinichi Uchida, Tatemitsu Rai. The Effects of Diuretics on the Progression of CKD and Incidence of Cardiovascular Events: Results from the CKD-ROUTE Study – A Prospective Cohort Study of Newly Visiting CKD Patients in Japan. The 48th Annual Meeting of American Society of Nephrology 2015.11.05 San Diego, USA

  5. Kikuchi H, Kanda E, Iimori S, Naito S, Sasaki S, Sohara E, Okado T,Rai T,Uchida S. Combination of low body mass index and serum albumin level leads to chronic kidney disease progression: the chronic kidney disease–research of outcomes in treatment and epidemiology study. The 48th Annual Meeting of American Society of Nephrology 2015.11.05 San Diego, USA

  6. Nomura Naohiro, Shoda Wakana, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi. Potassium-induced dephosphorylation of renal sodium-chloride cotransporter is NOT dependent on the anions. The 48th Annual Meeting of the American Society of Nephrology 2015.11.05 San Diego, USA

  7. Mandai S, Mori T, Sohara E, Rai T, Uchida S. Generation of Hypertension-Associated STK39 Polymorphism Knockin Cell Lines with the CRISPR/Cas9 System. The 48th Annual Meeting of American Society of Nephrology 2015.11.05 San Diego

  8. Mandai S, Kanda E, Iimori S, Naito S, Sohara E, Okado T, Sasaki S, Rai T, Uchida S. Association of Serum Chloride Level with Mortality and Cardiovascular Events in Chronic Kidney Disease: The CKD-ROUTE Study. The 48th Annual Meeting of American Society of Nephrology 2015.11.05 San Diego

  9. Susa Koichiro, Sohara Eisei, Takahashi Daiei, Rai Tatemitsu, Uchida Shinichi. The Major Contribution of WNK4 to the Pathogenesis of Pseudohypoaldosteronism Type II (PHAII) Caused by the KLHL3 Mutation R528H. The 48th Annual Meeting of American Society of Nephrology 2015.11.05 San Diego

  1. Koichiro Susa, Eisei Sohara, Tatemitsu Rai, Moko Zeniya, Yutaro Mori, Takayasu Mori, Motoko Chiga, Daiei Takahashi, Yuichi Inoue, Kiyoshi Isobe, Naoki Takeda, Sei Sasaki, Shinichi Uchida. Molecular Pathogenesis of PHAII in KLHL3R528H/+ Knock-In Mice. The 47th Annual Meeting of American Society of Nephrology 2014.11.15 Philadelphia

  2. Moko Zeniya, Nobuhisa Morimoto, Daiei Takahashi, Yutaro Mori, Takayasu Mori, Fumiaki Ando, Yuya Araki, Yuki Yoshizaki, Yuichi Inoue, Kiyoshi Ishobe, Naohiro Nomura, Katsuyuki Oi, Hidenori Nishida, Sei Sasaki, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida. KLHL2 mediates angiotensin II-WNK3 singaling involved in the regulation of vascular tonus. The 47th Annual Meeting of American Society of Nephrology 2014.11.15 Philadelphia

  3. Yutaro Mori, Mai Wakabayashi, Takayasu Mori, Moko Zeniya, Eisei Sohara, Tatemitsu Rai, Sei Sasaki, Shinichi Uchida. p62-mediated selective autophagy is involved in KLHL3-dependent WNK4 degradation . The 47th Annual Meeting of American Society of Nephrology 2014.11.15 Philadelphia

  4. Yuichi Inoue, Eisei Sohara, Katsuki Kobayashi, Tatemitsu Rai, Kenichi Ishibashi, Shigeo Horie, Xuefeng Su, Jing Zhou, Sei Sasaki, Shinichi Uchida. Elongated ciliary length of proximal tubules in a PKD model AQP11 knockout mouse. . The 47th Annual Meeting of American Society of Nephrology 2014.11.14 Philadelphia

  5. Takayasu Mori, Kazuyoshi Hosomichi, Eisei Sohara, Tatemitsu Rai, Sei Sasaki, Ituro Inoue, Shinichi Uchida.. Comprehensive diagnosis of hereditary kidney diseases by a customized diagnostic panel of targeted exome sequencing.. The 47th Annual Meeting of the American Society of Nephrology 2014.11 Philadelphia

  6. Shotaro Naito, Soichiro Iimori, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida, Sei Sasaki. Association between the blood pressure control status and one year decline of renal function in newly visited CKD patients in Japan. the 51st ERA-EDTA Congress 2014.05.31 Amsterdam, The Netherlands

  7. Yuichi Inoue, Eisei Sohara, Katsuki Kobayashi, Motoko Chiga, Tatemitsu Rai, Kenichi Ishibashi, Shigeo Horie, Xuefeng Su, Jing Zhou, Sei Sasaki, Shinichi Uchida. Aberrant glycosylation and localization of polycystin-1 cause polycystic kidney in AQP11-knockout mice.. The 14th Asian Pacific Congress of Nephrology 2014.05.17 Tokyo

  8. Soichiro Iimori, Hidenori Nishida, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida, Sei Sasaki.. Anemia management and cardiovascular risk in newly visited CKD patients in Japan. The 14th Asian Pacific Congress of Nephrology 2014.05.15

  1. Wakabayashi M, Mori T (co-first), Isobe K, Sohara E, Susa K, Araki Y, Chiga M, Kikuchi E, Nomura N, Mori Y, Matsuo H, Murata T, Nomura S, Asano T, Kawaguchi H, Nonoyama S, Rai T, Sasaki S, Uchida S.. Impaired KLHL3-Mediated Ubiquitination of WNK4 Activates OSR1 and SPAK Kinases-NaCl Cotransporter (NCC) Signaling and Causes Hypertension.. The 46th Annual Meeting of American Society of Nephrology, Atlanta 2013.11.01

  2. Mori T, Eriko K, Sohara E, Rai T, Sasaki S, Uchida S.. Chemical library screening for WNK signaling inhibitors by using fluorescent correlation spectroscopy.. The 46th Annual Meeting of American Society of Nephrology, Atlanta 2013.11.01

  1. Mori T, Sohara E, Rai T, Sasaki S, Uchida S.. Generation and analysis of WT-WNK4 transgenic mice revealed the physiological role of WNK4. The 45th Annual Meeting of American Society of Nephrology, San Diego. The 45th Annual Meeting of American Society of Nephrology, San Diego 2012.11.01

  1. Mori T, Ohta A, Sohara E, Rai T, Sasaki S, Uchida S.. High throughput screening of drugs that inhibit WNK-OSR1/SPAK signaling cascade.. The 44th Annual Meeting of American Society of Nephrology, Philadelphia 2011.11.01 Philadelphia

  1. Yutaro Mori. KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease. The 65th Annual Meeting of the Japanese Society of Nephrology 2022.06.12 Kobe, On-line

  2. Yutaro Mori. KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease. The 65th Annual Meeting of the Japanese Society of Nephrology 2022.06.11 Kobe, On-line

  1. Yutaro Mori, Seiji Kishi, Takaharu Ichimura, Joseph V. Bonventre. Elucidation of Pathophysiology and Drug Discovery for Diabetic Kidney Disease Targeting Kidney Injury Molecule-1 (KIM-1). The 44th Annual Meeting of the Molecular Biology Society of Japan 2021.12.02 Yokohama, On-line

  2. Yutaro Mori. My Experience on Working as a Postdoc Abroad. The 44th Annual Meeting of the Molecular Biology Society of Japan 2021.12.02 Yokohama, On-line

  1. Genetic background in clinically diagnosed Gitelman syndrome in adulthood and phenotypic characteristics of the mutation-negative cases. 2020.08

  2. MORI Yutaro. Aiming to Overcome Diabetic Kidney Disease -A Translational Research Starting From KIM-1-. 2020.02.21 Boston

  1. Eriko Takehara, Daiei Takahashi, Yujiro Nakano, Koichiro Susa, Moko Zeniya, Hidehiko Sato, Soichiro Iimori, Naohiro Nomura, Shotaro Naito, Eisei Sohara, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida. Severe alkarosis and hypokaremia in a patient with pancreatic neuroendocrine tumor. Rinsho Taieki 2016.10.29

  2. Wakana Shoda, Naohiro Nomura, Fumiaki Ando, Yutaro Mori, Takayasu Mori, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida. Calcineurin rapidly dephosphorylates sodium-chloride cotransporter in response to high potassium intake. The 26th Ochanomizu Jin Kenkyukai 2016.10.27 Tokyo

  3. Sohara E. WNK signaling and KLHL3/Cullin3 ubiquitin ligase complex in salt-sensitive hypertension. The 89th Annual Meeting of the Japanese Pharmacological Society 2016.02.09

  1. Shotaro Naito, Soichiro Iimori, Yuichi Inoue, Koichiro, Susa, Eisei Sohara, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida. The effect of educational hospitalization on CKD patients. The 58th Annual Meeting of Japanese Society of Nephrology 2015.06.06 Nagoya, Japan

To the head of this page.▲