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Hiroshi Hidaka, Kunio Tarasawa, Kenji Fujimori, Taku Obara, Kiyohide Fushimi, Akihiro Shimamura, Hiroshi Iwai: Identification of Risk Factors for Mortality and Prolonged Hospitalization in Patients Treated With Surgical Drainage for Otogenic Intracranial Complications: A Nationwide Study Using a Japanese Inpatient Database. Otol Neurotol. 2023.12; 44 (10): 1027-1032. ( PubMed , DOI )

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Ana B Villaseñor-Altamirano, Dhawal Jain, Yunju Jeong, Jaivardhan A Menon, Mari Kamiya, Hibah Haider, Reshmi Manandhar, Muhammad Dawood Amir Sheikh, Humra Athar, Louis T Merriam, Min Hyung Ryu, Takanori Sasaki, Peter J Castaldi, Deepak A Rao, Lynette M Sholl, Marina Vivero, Craig P Hersh, Xiaobo Zhou, Justus Veerkamp, Jeong H Yun, Edy Y Kim; MGB-Bayer Pulmonary Drug Discovery Lab: Activation of CD8+ T Cells in COPD Lung Am J Respir Crit Care Med. 2023.10; ( DOI )

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Mari Kamiya, Naoki Kimura, Natsuka Umezawa, Hisanori Hasegawa and Shinsuke Yasuda: Muscle fiber necroptosis in pathophysiology of idiopathic inflammatory myopathies and its potential as target of novel treatment strategy Frontiers in Immunology. 2023.07; 14 1191815. ( DOI )

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Keigo Sugisawa, Hiroshi Takase, Takahiko Sugihara, Tetsuya Saito, Yuko Iwasaki, Koju Kamoi, Tatsushi Kawaguchi, Shinsuke Yasuda, Kyoko Ohno-Matsui: Granulomatosis with Polyangiitis Complicated by Severe Exudative Retinal Detachment and Orbital Granuloma Successfully Controlled with Rituximab: A Case Report. Case Rep Ophthalmol. 2023.05; 14 (1): 214-222. ( PubMed , DOI )

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Nobuya Abe, Masaru Kato, Michihito Kono, Yuichiro Fujieda, Hiroshi Ohira, Ichizo Tsujino, Noriko Oyama-Manabe, Kenji Oku, Toshiyuki Bohgaki, Shinsuke Yasuda, Tatsuya Atsumi: Right ventricular dimension index by cardiac magnetic resonance for prognostication in connective tissue diseases and pulmonary hypertension. Rheumatology (Oxford, England). 2020.03; 59 (3): 622-633. ( PubMed , DOI )

Yokoyama-Kokuryo Waka, Yamazaki Hayato, Takeuchi Tsutomu, Amano Koichi, Kikuchi Jun, Kondo Tsuneo, Nakamura Seiji, Sakai Ryoko, Hirano Fumio, Nanki Toshihiro, Koike Ryuji, Harigai Masayoshi: Identification of molecules associated with response to abatacept in patients with rheumatoid arthritis ARTHRITIS RESEARCH & THERAPY. 2020.03; 22 (1): 46. ( PubMed , DOI )

Yuichiro Fujieda, Mototsugu Doi, Takuya Asaka, Masahiro Ota, Ryo Hisada, Naoki Ohnishi, Michihiro Kono, Hiraku Kameda, Daigo Nakazawa, Masaru Kato, Olga Amengual, Masahiko Takahata, Shinsuke Yasuda, Yoshimasa Kitagawa, Tatsuya Atsumi: Incidence and risk of antiresorptive agent-related osteonecrosis of the jaw (ARONJ) after tooth extraction in patients with autoimmune disease. Journal of bone and mineral metabolism. 2020.02; ( PubMed , DOI )

Noda S, Hasegawa H, Tokura M, Mizoguchi F, Kohsaka H: A Case of Systemic Lupus Erythematosus Presenting With Thrombotic Microangiopathy-Induced Cardiomyopathy. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. 2020.02; ( PubMed , DOI )

Kohei Karino, Michihiro Kono, Michihito Kono, Keita Sakamoto, Yuichiro Fujieda, Masaru Kato, Olga Amengual, Kenji Oku, Shinsuke Yasuda, Tatsuya Atsumi: Myofascia-dominant involvement on whole-body MRI as a risk factor for rapidly progressive interstitial lung disease in dermatomyositis. Rheumatology (Oxford, England). 2020.01; ( PubMed , DOI )

Utsunomiya M, Dobashi H, Odani T, Saito K, Yokogawa N, Nagasaka K, Takenaka K, Soejima M, Sugihara T, Hagiyama H, Hirata S, Matsui K, Nonomura Y, Kondo M, Suzuki F, Nawata Y, Tomita M, Kihara M, Yokoyama-Kokuryo W, Hirano F, Yamazaki H, Sakai R, Nanki T, Koike R, Miyasaka N, Harigai M: An open-label, randomized controlled trial of sulfamethoxazole-trimethoprim for Pneumocystis prophylaxis: results of 52-week follow-up. Rheumatology advances in practice. 2020; 4 (2): rkaa029. ( PubMed , DOI )

Nukui Y, Chino T, Tani C, Sonobe K, Aiso Y, Tohda S, Koike R, Saito R: Molecular epidemiologic and clinical analysis of Helicobacter cinaedi bacteremia in Japan. Helicobacter. 2019.11; e12675. ( PubMed , DOI )

Ryoichi Saito, Yukino Usui, Alafate Ayibieke, Jun Nakajima, Isaac Prah, Kazunari Sonobe, Yoshibumi Aiso, Shiori Ito, Yasuhiro Itsui, Yoshiro Hadano, Yoko Nukui, Ryuji Koike, Shuji Tohda: Hypervirulent clade 2, ribotype 019/sequence type 67 Clostridioides difficile strain from Japan. Gut Pathog. 2019.11; 11 54. ( PubMed , DOI )

Pregnancy outcomes in women with rheumatic diseases: a real-world observational study in Japan 2019.10; 28 (12): 1407-1416. ( PubMed , DOI )

Yoko Nukui, Alafate Ayibieke, Makoto Taniguchi, Yoshibumi Aiso, Yuka Shibuya, Kazunari Sonobe, Jun Nakajima, Saki Kanehira, Yoshiro Hadano, Shuji Tohda, Ryuji Koike, Ryoichi Saito: Whole-genome analysis of EC129, an NDM-5-, CTX-M-14-, OXA-10- and MCR-1-co-producing Escherichia coli ST167 strain isolated from Japan. J Glob Antimicrob Resist. 2019.09; 18 148-150. ( PubMed , DOI )

Kasai Shoko, Sakai Ryoko, Koike Ryuji, Kohsaka Hitoshi, Miyasaka Nobuyuki, Harigai Masayoshi: Higher risk of hospitalized infection, cardiovascular disease, and fracture in patients with rheumatoid arthritis determined using the Japanese health insurance database Modern Rheumatology. 2019.09; 29 (5): 788-794. ( ichushi )

Ryo Hisada, Masaru Kato, Eri Sugawara, Masatoshi Kanda, Yuichiro Fujieda, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, Shinsuke Yasuda, Tatsuya Atsumi: Circulating plasmablasts contribute to antiphospholipid antibody production, associated with type I interferon upregulation. Journal of thrombosis and haemostasis : JTH. 2019.07; 17 (7): 1134-1143. ( PubMed , DOI )

Takashi Okumura, Yumi Horie, Chen-Yi Lai, Huan-Ting Lin, Hirofumi Shoda, Bunki Natsumoto, Keishi Fujio, Eri Kumaki, Tsubasa Okano, Shintaro Ono, Kay Tanita, Tomohiro Morio, Hirokazu Kanegane, Hisanori Hasegawa, Fumitaka Mizoguchi, Kimito Kawahata, Hitoshi Kohsaka, Hiroshi Moritake, Hiroyuki Nunoi, Hironori Waki, Shin-Ichi Tamaru, Takayoshi Sasako, Toshimasa Yamauchi, Takashi Kadowaki, Hiroyuki Tanaka, Sachiko Kitanaka, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Makoto Otsu: Robust and highly efficient hiPSC generation from patient non-mobilized peripheral blood-derived CD34+ cells using the auto-erasable Sendai virus vector. Stem Cell Res Ther. 2019.06; 10 (1): 185. ( PubMed , DOI )

Kamiya M, Mizoguchi F, Takamura A, Kimura N, Kawahata K, Kohsaka H: A new in vitro model of polymyositis reveals CD8+ T cell invasion into muscle cells and its cytotoxic role. Rheumatology (Oxford, England). 2019.06; ( PubMed , DOI )

FACTORS THAT AFFECT THE RESPONSE TO TOCILIZUMAB WITH REGARD TO WORK PRODUCTIVITY IN PATIENTS WITH RHEUMATOID ARTHRITIS: A 2-YEAR FOLLOW-UP OF THE FIRST ACT-SC STUDY 2019.06; 78 1667. ( DOI )

Kazumasa Ohmura, Kenji Oku, Tamao Kitaori, Olga Amengual, Ryo Hisada, Masatoshi Kanda, Yuka Shimizu, Yuichiro Fujieda, Masaru Kato, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Mayumi Sugiura-Ogasawara, Tatsuya Atsumi: Pathogenic roles of anti-C1q antibodies in recurrent pregnancy loss. Clinical immunology (Orlando, Fla.). 2019.06; 203 37-44. ( PubMed , DOI )

Kanako Watanabe-Kusunoki, Nobuya Abe, Daigo Nakazawa, Kohei Karino, Fumihiko Hattanda, Yuichiro Fujieda, Saori Nishio, Shinsuke Yasuda, Akihiro Ishizu, Tatsuya Atsumi: A case report dysregulated neutrophil extracellular traps in a patient with propylthiouracil-induced anti-neutrophil cytoplasmic antibody-associated vasculitis. Medicine. 2019.04; 98 (17): e15328. ( PubMed , DOI )

Masatoshi Takagi, Chitose Ogawa, Yuki Aoki-Nogami, Tomoko Iehara, Eri Ishibashi, Minoru Imai, Tetsuro Kihara, Kiyoshi Nobori, Kazuhisa Hasebe, Shuki Mizutani, Toshimi Kimura, Masashi Nagata, Masato Yasuhara, Kenichi Yoshimura, Pariko Yorozu, Hajime Hosoi, Ryuji Koike: Phase I clinical study of oral olaparib in pediatric patients with refractory solid tumors: study protocol. BMC Pediatr. 2019.01; 19 (1): 31. ( PubMed , DOI )

Kameda Hideto, Fujii Takao, Nakajima Ayako, Koike Ryuji, Sagawa Akira, Kanbe Katsuaki, Tomita Tetsuya, Harigai Masayoshi, Suzuki Yasuo, Japan College of Rheumatology subcommittee on the guideline for the use of methotrexate in patients with rheumatoid arthritis: Japan College of Rheumatology guideline for the use of methotrexate in patients with rheumatoid arthritis Modern Rheumatology. 2019.01; 29 (1): 31-40. ( ichushi )

Nobuya Abe, Yuichiro Fujieda, Kentaro Nagaoka, Misako Ohkusu, Shinsuke Yasuda, Katsuhiko Kamei, Tatsuya Atsumi: Disseminated Cryptococcosis with Bronchiolitis and Cellulitis. American journal of respiratory and critical care medicine. 2019.01; 199 (2): 235-236. ( PubMed , DOI )

Michihiro Kono, Takashi Kurita, Shinsuke Yasuda, Michihito Kono, Yuichiro Fujieda, Toshiyuki Bohgaki, Takayuki Katsuyama, George C Tsokos, Vaishali R Moulton, Tatsuya Atsumi: Decreased Expression of Serine/Arginine-Rich Splicing Factor 1 in T Cells From Patients With Active Systemic Lupus Erythematosus Accounts for Reduced Expression of RasGRP1 and DNA Methyltransferase 1. Arthritis & rheumatology (Hoboken, N.J.). 2018.12; 70 (12): 2046-2056. ( PubMed , DOI )

Hiroyuki Nakamura, Sanae Shimamura, Shinsuke Yasuda, Michihito Kono, Michihiro Kono, Yuichiro Fujieda, Masaru Kato, Kenji Oku, Toshiyuki Bohgaki, Tomohiro Shimizu, Norimasa Iwasaki, Tatsuya Atsumi: Ectopic RASGRP2 (CalDAG-GEFI) expression in rheumatoid synovium contributes to the development of destructive arthritis. Annals of the rheumatic diseases. 2018.12; 77 (12): 1765-1772. ( PubMed , DOI )

Kasai S, Sakai R, Koike R, Kohsaka H, Miyasaka N, Harigai M: Higher risk of hospitalized infection, cardiovascular disease, and fracture in patients with rheumatoid arthritis determined using the Japanese health insurance database. Modern rheumatology. 2018.11; 1-7. ( PubMed , DOI )

Sugihara Takahiko, Ishizaki Tatsuro, Baba Hiroyuki, Matsumoto Takumi, Iga Shoko, Kusuda Takeshi, Tsuchida Marina, Kamiya Mari, Komiya Yoji, Hirano Fumio, Hosoya Tadashi, Miyasaka Nobuyuki, Harigai Masayoshi: Three Year Outcomes of Patients with Elderly-Onset Rheumatoid Arthritis Treated with a Therapeutic Strategy Targeting Low Disease Activity, and Impact of Adverse Events on Physical Function ARTHRITIS & RHEUMATOLOGY. 2018.09; 70

Fumi Sato-Kaneko, Xiaodong Wang, Shiyin Yao, Tadashi Hosoya, Fitzgerald S. Lao, Karen Messer, Minya Pu, Nikunj M. Shukla, Howard B. Cottam, Michael Chan, Dennis A. Carson, Maripat Corr, and Tomoko Hayashi: Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy BioMed Research International. 2018.09; ( DOI )

Shun Tanimura, Yuichiro Fujieda, Michihiro Kono, Yuhei Shibata, Ryo Hisada, Eri Sugawara, Hiroyuki Nakamura, Kazumasa Ohmura, Sanae Shimamura, Asako Mitani, Haruki Shida, Toshiyuki Watanabe, Masaru Kato, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Shinsuke Yasuda, Chikara Shimizu, Tatsuya Atsumi: Clinical significance of plasma presepsin levels in patients with systemic lupus erythematosus. Modern rheumatology. 2018.09; 28 (5): 865-871. ( PubMed , DOI )

Oku Kenji, Atsumi Tatsuya, Akiyama Yuji, Amano Hirofumi, Azuma Naoto, Bohgaki Toshiyuki, Funakubo Asanuma Yu, Horita Tetsuya, Hosoya Tadashi, Ichinose Kunihiro, Kato Masaru, Katsumata Yasuhiro, Kawaguchi Yasushi, Kawakami Atsushi, Koga Tomohiro, Kohsaka Hitoshi, Kondo Yuya, Kubo Kanae, Kuwana Masataka, Mimori Akio, Mimori Tsuneyo, Mimura Toshihide, Murakami Kosaku, Nakano Kazuhisa, Nakayamada Shingo, Ogishima Hiroshi, Ohmura Kazumasa, Saito Kazuyoshi, Sano Hajime, Shibuya Mihoko, Takahashi Yuko, Takasaki Yoshinari, Takeuchi Tsutomu, Tamura Naoto, Tanaka Yoshiya, Tsuboi Hiroto, Tsunoda Shinichiro, Yukawa Naoichiro, Yamakawa Noriyuki, Yamamoto Kazuhiko, Sumida Takayuki: Systemic Lupus International Collaborating Clinics(SLICC)によって確立された全身性エリテマトーデスの代替分類基準の評価(Evaluation of the alternative classification criteria of systemic lupus erythematosus established by Systemic Lupus International Collaborating Clinics(SLICC)) Modern Rheumatology. 2018.07; 28 (4): 642-648. ( ichushi )

Tadashi Hosoya, Fumi Sato-Kaneko, Alast Ahmadi, Shiyin Yao, Fitzgerald Lao, Kazutaka Kitaura, Takaji Matsutani, Dennis A Carson, Tomoko Hayashi: Induction of oligoclonal CD8 T cell responses against pulmonary metastatic cancer by a phospholipid-conjugated TLR7 agonist. Proc. Natl. Acad. Sci. U.S.A.. 2018.07; 115 (29): E6836-E6844. ( PubMed , DOI )

Kenji Oku, Tatsuya Atsumi, Yuji Akiyama, Hirofumi Amano, Naoto Azuma, Toshiyuki Bohgaki, Yu Funakubo Asanuma, Tetsuya Horita, Tadashi Hosoya, Kunihiro Ichinose, Masaru Kato, Yasuhiro Katsumata, Yasushi Kawaguchi, Atsushi Kawakami, Tomohiro Koga, Hitoshi Kohsaka, Yuya Kondo, Kanae Kubo, Masataka Kuwana, Akio Mimori, Tsuneyo Mimori, Toshihide Mimura, Kosaku Murakami, Kazuhisa Nakano, Shingo Nakayamada, Hiroshi Ogishima, Kazumasa Ohmura, Kazuyoshi Saito, Hajime Sano, Mihoko Shibuya, Yuko Takahashi, Yoshinari Takasaki, Tsutomu Takeuchi, Naoto Tamura, Yoshiya Tanaka, Hiroto Tsuboi, Shinichiro Tsunoda, Naoichiro Yukawa, Noriyuki Yamakawa, Kazuhiko Yamamoto, Takayuki Sumida: Evaluation of the alternative classification criteria of systemic lupus erythematosus established by Systemic Lupus International Collaborating Clinics (SLICC). Mod Rheumatol. 2018.07; 28 (4): 642-648. ( PubMed , DOI )

Shimizu Y, Yasuda S, Kimura T, Nishio S, Kono M, Ohmura K, Shimamura S, Kono M, Fujieda Y, Kato M, Oku K, Bohgaki T, Fukasawa Y, Tanaka S, Atsumi T: Interferon-inducible Mx1 protein is highly expressed in renal tissues from treatment-naïve lupus nephritis, but not in those under immunosuppressive treatment. Modern rheumatology. 2018.07; 28 (4): 661-669. ( PubMed , DOI )

Hideto Kameda, Takao Fujii, Ayako Nakajima, Ryuji Koike, Akira Sagawa, Katsuaki Kanbe, Tetsuya Tomita, Masayoshi Harigai, Yasuo Suzuki, : Japan College of Rheumatology guideline for the use of methotrexate in patients with rheumatoid arthritis. Mod Rheumatol. 2018.05; 1-10. ( PubMed , DOI )

Nikunj M Shukla, Kei-Ichiro Arimoto, Shiyin Yao, Jun-Bao Fan, Yue Zhang, Fumi Sato-Kaneko, Fitzgerald S Lao, Tadashi Hosoya, Karen Messer, Minya Pu, Howard B Cottam, Dennis A Carson, Tomoko Hayashi, Dong-Er Zhang, Maripat Corr: Identification of Compounds That Prolong Type I Interferon Signaling as Potential Vaccine Adjuvants. SLAS Discov. 2018.05; 23 (9): 2472555218774308. ( PubMed , DOI )

M. Kono, S. Yasuda, M. Kono, T. Atsumi: Tocilizumab reduced production of systemic sclerosis-related autoantibodies and anti-cyclic citrullinated protein antibodies in two patients with overlapping systemic sclerosis and rheumatoid arthritis Scandinavian Journal of Rheumatology. 2018.05; 47 (3): 248-250. ( PubMed , DOI )

Umezawa Natsuka, Kawahata Kimito, Mizoguchi Fumitaka, Kimura Naoki, Yoshihashi-Nakazato Yoko, Miyasaka Nobuyuki, Kohsaka Hitoshi: Interleukin-23 as a therapeutic target for inflammatory myopathy SCIENTIFIC REPORTS. 2018.04; 8 (1): 5498. ( PubMed , DOI )

Ryoko Sakai, Shoko Kasai, Fumio Hirano, Sayoko Harada, Mari Kihara, Waka Yokoyama, Michi Tsutsumino, Kenji Nagasaka, Ryuji Koike, Hisashi Yamanaka, Nobuyuki Miyasaka, Masayoshi Harigai: No increased risk of herpes zoster in TNF inhibitor and non-TNF inhibitor users with rheumatoid arthritis: epidemiological study using the Japanese health insurance database. Int J Rheum Dis. 2018.04; ( PubMed , DOI )

Ogihara Shinji, Saito Ryoichi, Sawabe Etsuko, Kozakai Takahiro, Shima Mari, Aiso Yoshibumi, Fujie Toshihide, Nukui Yoko, Koike Ryuji, Hagihara Michio, Tohda Shuji: Molecular typing of methicillin-resistant Staphylococcus aureus: Comparison of PCR-based open reading frame typing, multilocus sequence typing, and Staphylococcus protein A gene typing Journal of Infection and Chemotherapy. 2018.04; 24 (3-4): 312-314. ( ichushi )

Kazumasa Ohmura, Masaru Kato, Toshiyuki Watanabe, Kenji Oku, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Yoichi M Ito, Norihiro Sato, Tatsuya Atsumi: Effect of combined treatment with bisphosphonate and vitamin D on atherosclerosis in patients with systemic lupus erythematosus: a propensity score-based analysis. Arthritis research & therapy. 2018.04; 20 (1): 72. ( PubMed , DOI )

Masaru Kato, Shinsuke Yasuda, Tatsuya Atsumi: The role of genetics and epigenetics in rheumatic diseases: are they really a target to be aimed at? Rheumatology International. 2018.04; 38 (8): 1-6. ( PubMed , DOI )

Hiroyuki Nakamura, Kenji Oku, Yusuke Ogata, Kazumasa Ohmura, Yoko Yoshida, Etsuko Kitano, Yuichiro Fujieda, Masaru Kato, Toshiyuki Bohgaki, Olga Amengual, Shinsuke Yasuda, Yoshihiro Fujimura, Tsukasa Seya, Tatsuya Atsumi: Alternative pathway activation due to low level of complement factor H in primary antiphospholipid syndrome. Thrombosis research. 2018.04; 164 63-68. ( PubMed , DOI )

Hiroyuki Nakamura, Kenji Oku, Olga Amengual, Kazumasa Ohmura, Yuichiro Fujieda, Masaru Kato, Toshiyuki Bohgaki, Shinsuke Yasuda, Tatsuya Atsumi: First-Line, Non-Criterial Antiphospholipid Antibody Testing for the Diagnosis of Antiphospholipid Syndrome in Clinical Practice: A Combination of Anti-β2 -Glycoprotein I Domain I and Anti-Phosphatidylserine/Prothrombin Complex Antibodies Tests. Arthritis care & research. 2018.04; 70 (4): 627-634. ( PubMed , DOI )

Shinji Ogihara, Ryoichi Saito, Etsuko Sawabe, Takahiro Kozakai, Mari Shima, Yoshibumi Aiso, Toshihide Fujie, Yoko Nukui, Ryuji Koike, Michio Hagihara, Shuji Tohda: Molecular typing of methicillin-resistant Staphylococcus aureus: Comparison of PCR-based open reading frame typing, multilocus sequence typing, and Staphylococcus protein A gene typing. J. Infect. Chemother.. 2018.04; 24 (4): 312-314. ( PubMed , DOI )

Honda Suguru, Hirano Fumio, Mouri Mariko, Hasegawa Hisanori, Kohsaka Hitoshi: Aneurysm formation after stent grafting in vascular Behcet's disease ARTHRITIS & RHEUMATOLOGY. 2018.02; 70 (2): 322. ( PubMed , DOI )

T. Watanabe, K. Oku, O. Amengual, R. Hisada, K. Ohmura, I. Nakagawa, H. Shida, T. Bohgaki, T. Horita, S. Yasuda, T. Atsumi: Effects of statins on thrombosis development in patients with systemic lupus erythematosus and antiphospholipid antibodies Lupus. 2018.02; 27 (2): 225-234. ( PubMed , DOI )

Simone Mader, Venkatesh Jeganathan, Yoshiyuki Arinuma, Yuichiro Fujieda, Irena Dujmovic, Jelena Drulovic, Yuka Shimizu, Yuko Sakuma, Joel N. H. Stern, Cynthia Aranow, Meggan Mackay, Shinsuke Yasuda, Tatsuya Atsumi, Shunsei Hirohata, Betty Diamond: Understanding the Antibody Repertoire in Neuropsychiatric Systemic Lupus Erythematosus and Neuromyelitis Optica Spectrum Disorder: Do They Share Common Targets? Arthritis and Rheumatology. 2018.02; 70 (2): 277-286. ( PubMed , DOI )

Fumi Sato-Kaneko, Xiaodong Wang, Shiyin Yao, Tadashi Hosoya, Fitzgerald S Lao, Karen Messer, Minya Pu, Nikunj M Shukla, Howard B Cottam, Michael Chan, Dennis A Carson, Maripat Corr, Tomoko Hayashi: Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy. BioMed research international. 2018; 2018 8091283. ( PubMed , DOI )

Harigai Masayoshi, Utsunomiya Masako, Dobashi Hiroaki, Odani Toshio, Saito Kazuyoshi, Yokogawa Naoto, Nagasaka Kenji, Takenaka Kenchi, Soejima Makoto, Sugihara Takahiko, Hagiyama Hiroyuki, Hirata Shinya, Matsui Kazuo, Nonomura Yoshinori, Kondo Masahiro, Suzuki Fumihito, Tomita Makoto, Kihara Mari, Yokoyama Waka, Hirano Fumio, Yamazaki Hayato, Sakai Ryoko, Nanki Toshihiro, Koike Ryuji, Kohsaka Hitoshi, Miyasaka Nobuyuki: Optimal Regimens of Sulfamethoxazole-Trimethoprim for Chemoprophylaxis of Pneumocystis Pneumonia in Patients with Systemic Rheumatic Diseases: 52-Week Follow-up of a Non-Blinded, Randomized Controlled Trial ARTHRITIS & RHEUMATOLOGY. 2017.10; 69

Hiroyuki Nakamura, Masaru Kato, Toshitaka Nakaya, Michihiro Kono, Shun Tanimura, Takahiro Sato, Yuichiro Fujieda, Kenji Oku, Hiroshi Ohira, Toshiyuki Bohgaki, Shinsuke Yasuda, Ichizo Tsujino, Masaharu Nishimura, Tatsuya Atsumi: Decreased haptoglobin levels inversely correlated with pulmonary artery pressure in patients with pulmonary arterial hypertension: A cross-sectional study MEDICINE. 2017.10; 96 (43): e8349. ( PubMed , DOI )

Hiroyuki Nakamura, Shinsuke Yasuda, Atsushi Noguchi, Toshio Odani, Yuichiro Fujieda, Masaru Kato, Kenji Oku, Junichi Sugita, Toshiyuki Bohgaki, Tomoyuki Endo, Takanori Teshima, Tatsuya Atsumi: Long-Term Follow-up Report on Japanese Patients with Severe Systemic Sclerosis after Autologous Hematopoietic Stem Cell Transplantation ARTHRITIS & RHEUMATOLOGY. 2017.10; 69

Nobuya Abe, Kenji Oku, Olga Amengual, Yuichiro Fujieda, Masaru Kato, Toshiyuki Bohgaki, Shinsuke Yasuda, Rintaro Mori, Eriko Morishita, Katsue Suzuki-Inoue, Tatsuya Atsumi: Possible Therapeutics for Antiphospholipid Antibody Related Thrombocytopenia: A Systemic Review and Meta-Analysis ARTHRITIS & RHEUMATOLOGY. 2017.10; 69

Yoshiya Tanaka, Hideto Kameda, Kazuyoshi Saito, Yuko Kaneko, Eiichi Tanaka, Shinsuke Yasuda, Naoto Tamura, Keishi Fujio, Takao Fujii, Toshihisa Kojima, Tatsuhiko Anzai, Chikuma Hamada, Yoshihisa Fujino, Shinya Matsuda, Hitoshi Kohsaka: Improvement in Overall Work Productivity Among Biologic-NaiVe Patients with Rheumatoid Arthritis Treated with Tocilizumab Subcutaneous Injection: A Prospective, Real World, Observational Study in Japan ARTHRITIS & RHEUMATOLOGY. 2017.10; 69

Fumi Sato-Kaneko, Shiyin Yao, Alast Ahmadi, Shannon S Zhang, Tadashi Hosoya, Megan M Kaneda, Judith A Varner, Minya Pu, Karen S Messer, Cristiana Guiducci, Robert L Coffman, Kazutaka Kitaura, Takaji Matsutani, Ryuji Suzuki, Dennis A Carson, Tomoko Hayashi, Ezra Ew Cohen: Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer. JCI Insight. 2017.09; 2 (18): ( PubMed , DOI )

R. Hisada, M. Kato, E. Sugawara, Y. Fujieda, K. Oku, T. Bohgaki, O. Amengual, S. Yasuda, T. Atsumi: Thrombotic risk stratification by platelet count in patients with antiphospholipid antibodies: a longitudinal study JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2017.09; 15 (9): 1782-1787. ( PubMed , DOI )

Hirano Fumio, Yokoyama Waka, Yamazaki Hayato, Amano Koichi, Kawakami Atsushi, Hayashi Taichi, Tamura Naoto, Yasuda Shinsuke, Dobashi Hiroaki, Fujii Takao, Ito Satoshi, Kaneko Yuko, Matsui Toshihiro, Okuda Yasuaki, Saito Kazuyoshi, Suzuki Fumihito, Yoshimi Ryusuke, Sakai Ryoko, Koike Ryuji, Kohsaka Hitoshi, Miyasaka Nobuyuki, Harigai Masayoshi, T2T Epidemiological Study Group: 活動性関節リウマチ患者におけるsimplified disease activity index寛解到達は目標達成に向けた治療方針下の実際の臨床環境におけるその後の良好な機能的および構造的転帰に関連する(Achieving simplified disease activity index remission in patients with active rheumatoid arthritis is associated with subsequent good functional and structural outcomes in a real-world clinical setting under a treat-to-target strategy) Modern Rheumatology. 2017.09; 27 (5): 811-819. ( ichushi )

Yamazaki Hayato, Hirano Fumio, Takeuchi Tsutomu, Amano Koichi, Kikuchi Jun, Kihara Mari, Yokoyama Waka, Sugihara Takahiko, Nagasaka Kenji, Hagiyama Hiroyuki, Nonomura Yoshinori, Sakai Ryoko, Tanaka Michi, Koike Ryuji, Nanki Toshihiro, Kohsaka Hitoshi, Miyasaka Nobuyuki, Harigai Masayoshi: 関節リウマチ患者におけるアバタセプト治療中の6ヵ月時のSimplified Disease Activity Index寛解は12ヵ月時の機能的および構造的寛解の独立予測因子である　日本における多施設共同前向きコホート研究(Simplified Disease Activity Index remission at month 6 is an independent predictor of functional and structural remissions at month 12 during abatacept treatment in patients with rheumatoid arthritis: A multi-center, prospective cohort study in Japan) Modern Rheumatology. 2017.09; 27 (5): 787-794. ( ichushi )

Tatsuya Atsumi, Yoshiya Tanaka, Kazuhiko Yamamoto, Tsutomu Takeuchi, Hisashi Yamanaka, Naoki Ishiguro, Katsumi Eguchi, Akira Watanabe, Hideki Origasa, Shinsuke Yasuda, Yuji Yamanishi, Yasuhiko Kita, Tsukasa Matsubara, Masahiro Iwamoto, Toshiharu Shoji, Osamu Togo, Toshiyuki Okada, Desiree van der Heijde, Nobuyuki Miyasaka, Takao Koike: Clinical benefit of 1-year certolizumab pegol (CZP) add-on therapy to methotrexate treatment in patients with early rheumatoid arthritis was observed following CZP discontinuation: 2-year results of the C-OPERA study, a phase III randomised trial ANNALS OF THE RHEUMATIC DISEASES. 2017.08; 76 (8): 1348-1356. ( PubMed , DOI )

Kenji Oku, Olga Amengual, Shinsuke Yasuda, Tatsuya Atsumi: How to Identify High-Risk APS Patients: Clinical Utility and Predictive Values of Validated Scores CURRENT RHEUMATOLOGY REPORTS. 2017.08; 19 (8): 51. ( PubMed , DOI )

Hisanori Hasegawa, Kimito Kawahata, Fumitaka Mizoguchi, Naoko Okiyama, Nobuyuki Miyasaka, Hitoshi Kohsaka: Direct suppression of autoaggressive CD8+ T cells with CD80/86 blockade in CD8+ T cell-mediated polymyositis models of mice. Clin. Exp. Rheumatol.. 2017.07; 35 (4): 593-597. ( PubMed )

Hideto Takada, Naoki Kimura, Yoko Yoshihashi-Nakazato, Kimito Kawahata, Hitoshi Kohsaka: Discoid Lupus Erythematosus Complicated with Pregnancy-induced Hemophagocytic Syndrome. Intern. Med.. 2017.07; 56 (12): 1581-1583. ( PubMed , DOI )

Takada Hideto, Kimura Naoki, Yoshihashi-Nakazato Yoko, Kawahata Kimito, Kohsaka Hitoshi: 妊娠誘発性血球貪食症候群を合併した円板状エリテマトーデス(Discoid Lupus Erythematosus Complicated with Pregnancy-induced Hemophagocytic Syndrome) Internal Medicine. 2017.06; 56 (12): 1581-1583. ( ichushi )

H. Nakamura, O. Amengual, T. Horita, M. Kato, K. Oku, T. Bohgaki, S. Yasuda, T. Atsumi: Acute aortic thrombosis related to antiphospholipid antibodies LUPUS. 2017.06; 26 (7): 783-784. ( PubMed , DOI )

R. Hisada, M. Kato, N. Ohnishi, M. Kono, S. Tanimura, E. Sugawara, H. Nakamura, K. Ohmura, S. Shimamura, Y. Fujieda, K. Oku, T. Bohgaki, O. Amengual, S. Yasuda, T. Atsumi: HIGH RISK OF IDIOPATHIC OSTEONECROSIS IN SLE PATIENTS WITH HIGH ANTIPHOSPHOLIPID SCORE AND HYPERTRIGLYCERIDEMIA ANNALS OF THE RHEUMATIC DISEASES. 2017.06; 76 598. ( DOI )

H. Nakamura, M. Kato, M. Kono, S. Tanimura, R. Hisada, E. Sugawara, K. Ohmura, S. Shimamura, Y. Fujieda, K. Oku, T. Bohgaki, O. Amengual, S. Yasuda, T. Atsumi: USEFULNESS OF SERUM HAPTOGLOBIN LEVELS AS A NOVEL MARKER FOR PULMONARY ARTERIAL HYPERTENSION COMPLICATED WITH CONNECTIVE TISSUE DISEASE ANNALS OF THE RHEUMATIC DISEASES. 2017.06; 76 624-625. ( DOI )

K. Ohmura, K. Oku, T. Kitaori, M. Kono, S. Tanimura, E. Sugawara, R. Hisada, H. Nakamura, S. Shimamura, Y. Fujieda, M. Kato, T. Bohgaki, O. Amengual, S. Yasuda, M. Sugiura-Ogasawara, T. Atsumi: AUTOANTIBODY AGAINST COMPLEMENT COMPONENT 1Q SUBCOMPONENT IS ASSOCIATED WITH THE PATHOGENESIS OF RECURRENT PREGNANCY LOSS ANNALS OF THE RHEUMATIC DISEASES. 2017.06; 76 1453-1454. ( DOI )

Shinsuke Yasuda, Yuka Shimizu, Tatsuya Atsumi: Brain MRI abnormalities defined as risks for poor prognosis in lupus patients with acute confusional state: Are they antibody mediated? MODERN RHEUMATOLOGY. 2017.03; 27 (2): 191-192. ( PubMed , DOI )

Masako Utsunomiya, Hiroaki Dobashi, Toshio Odani, Kazuyoshi Saito, Naoto Yokogawa, Kenji Nagasaka, Kenchi Takenaka, Makoto Soejima, Takahiko Sugihara, Hiroyuki Hagiyama, Shinya Hirata, Kazuo Matsui, Yoshinori Nonomura, Masahiro Kondo, Fumihito Suzuki, Makoto Tomita, Mari Kihara, Waka Yokoyama, Fumio Hirano, Hayato Yamazaki, Ryoko Sakai, Toshihiro Nanki, Ryuji Koike, Hitoshi Kohsaka, Nobuyuki Miyasaka, Masayoshi Harigai: Optimal regimens of sulfamethoxazole-trimethoprim for chemoprophylaxis of Pneumocystis pneumonia in patients with systemic rheumatic diseases: results from a non-blinded, randomized controlled trial. Arthritis Research and Therapeutics. 2017.01; 19 (1): 7. ( PubMed , DOI )

Michihiro Kono, Shinsuke Yasuda, Tatsuya Atsumi: Takayasu Arteritis with Varied-size Vessel Involvement JOURNAL OF RHEUMATOLOGY. 2017.01; 44 (1): 125-126. ( PubMed , DOI )

Michihito Kono, Tamotsu Kamishima, Shinsuke Yasuda, Keita Sakamoto, Sawako Abe, Atsushi Noguchi, Toshiyuki Watanabe, Yuka Shimizu, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, Tatsuya Atsumi: Effectiveness of whole-body magnetic resonance imaging for the efficacy of biologic anti-rheumatic drugs in patients with rheumatoid arthritis: A retrospective pilot study MODERN RHEUMATOLOGY. 2017; 27 (6): 953-960. ( PubMed , DOI )

Shinsuke Yasuda, Kazumasa Ohmura, Hiroshi Kanazawa, Takashi Kurita, Yujiro Kon, Tomonori Ishii, Yuichiro Fujieda, Satoshi Jodo, Kazuhide Tanimura, Michio Minami, Tomomasa Izumiyama, Takumi Matsumoto, Yoshiharu Amasaki, Yoko Suzuki, Hideki Kasahara, Naofumi Yamauchi, Masaru Kato, Tamotsu Kamishima, Akito Tsutsumi, Hiromitsu Takemori, Takao Koike, Tatsuya Atsumi: Maintenance treatment using abatacept with dose reduction after achievement of low disease activity in patients with rheumatoid arthritis (MATADOR) - A prospective, multicenter, single arm pilot clinical trial MODERN RHEUMATOLOGY. 2017; 27 (6): 930-937. ( PubMed , DOI )

Eri Sugawara, Masaru Kato, Ryo Hisada, Kenji Oku, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Tatsuya Atsumi: Treatment of Vasodilator-resistant Mixed Connective Tissue Disease-associated Pulmonary Arterial Hypertension with Glucocorticoid and Cyclophosphamide INTERNAL MEDICINE. 2017; 56 (4): 445-448. ( PubMed , DOI )

Atsushi Noguchi, Masaru Kato, Michihito Kono, Kazumasa Ohmura, Hiroshi Ohira, Ichizo Tsujino, Noriko Oyama-Manabe, Kenji Oku, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Masaharu Nishimura, Tatsuya Atsumi: Bi-ventricular interplay in patients with systemic sclerosis-associated pulmonary arterial hypertension: Detection by cardiac magnetic resonance MODERN RHEUMATOLOGY. 2017; 27 (3): 481-488. ( PubMed , DOI )

Hayato Yamazaki, Fumio Hirano, Tsutomu Takeuchi, Koichi Amano, Jun Kikuchi, Mari Kihara, Waka Yokoyama, Takahiko Sugihara, Kenji Nagasaka, Hiroyuki Hagiyama, Yoshinori Nonomura, Ryoko Sakai, Michi Tanaka, Ryuji Koike, Toshihiro Nanki, Hitoshi Kohsaka, Nobuyuki Miyasaka, Masayoshi Harigai: Simplified Disease Activity Index remission at month 6 is an independent predictor of functional and structural remissions at month 12 during abatacept treatment in patients with rheumatoid arthritis: A multi-center, prospective cohort study in Japan. Mod Rheumatol. 2016.12; 1-8. ( PubMed , DOI )

Fumio Hirano, Waka Yokoyama, Hayato Yamazaki, Koichi Amano, Atsushi Kawakami, Taichi Hayashi, Naoto Tamura, Shinsuke Yasuda, Hiroaki Dobashi, Takao Fujii, Satoshi Ito, Yuko Kaneko, Toshihiro Matsui, Yasuaki Okuda, Kazuyoshi Saito, Fumihito Suzuki, Ryusuke Yoshimi, Ryoko Sakai, Ryuji Koike, Hitoshi Kohsaka, Nobuyuki Miyasaka, Masayoshi Harigai, : Achieving simplified disease activity index remission in patients with active rheumatoid arthritis is associated with subsequent good functional and structural outcomes in a real-world clinical setting under a treat-to-target strategy. Mod Rheumatol. 2016.12; 1-9. ( PubMed , DOI )

Gene Igawa, Mika Casey, Etsuko Sawabe, Yoko Nukui, Shu Okugawa, Kyoji Moriya, Ryuji Koike, Shuji Tohda, Ryoichi Saito: Comparison of agar dilution and broth microdilution methods for Clostridium difficile antimicrobial susceptibility testing. J Glob Antimicrob Resist. 2016.12; 43-45. ( PubMed , DOI )

Honda Y, Nagai T, Ikeda Y, Sakakibara M, Asakawa N, Nagano N, Nakai M, Nishimura K, Sugano Y, Ohta-Ogo K, Asaumi Y, Aiba T, Kanzaki H, Kusano K, Noguchi T, Yasuda S, Tsutsui H, Ishibashi-Ueda H, Anzai T: Myocardial Immunocompetent Cells and Macrophage Phenotypes as Histopathological Surrogates for Diagnosis of Cardiac Sarcoidosis in Japanese. Journal of the American Heart Association. 2016.11; 5 (11): ( PubMed , DOI )

Kenji Oku, Hiroyuki Nakamura, Michihiro Kono, Kazumasa Ohmura, Masaru Kato, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Olga Amengual, Tatsuya Atsumi: Complement and thrombosis in the antiphospholipid syndrome AUTOIMMUNITY REVIEWS. 2016.10; 15 (10): 1001-1004. ( PubMed , DOI )

Kenji Oku, Olga Amengual, Masaru Kato, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Naoya Sakamoto, Masahiro Ieko, Gary L. Norman, Tatsuya Atsumi: Significance of fully automated tests for the diagnosis of antiphospholipid syndrome THROMBOSIS RESEARCH. 2016.10; 146 1-6. ( PubMed , DOI )

Shinsuke Yasuda, Kazumasa Ohmura, Hiroshi Kanazawa, Takashi Kurita, Yujiro Kon, Tomonori Ishii, Satoshi Jodo, Kazuhide Tanimura, Michio Minami, Tomomasa Izumiyama, Takumi Matsumoto, Yoshiharu Amasaki, Yoko Suzuki, Hideki Kasahara, Naofumi Yamauchi, Akito Tsutsumi, Hiromitsu Takemori, Takao Koike, Tatsuya Atsumi: Maintenance Treatment Using Abatacept with Dose Reduction after Achievement of Low Disease Activity in Patients with Rheumatoid Arthritis (MATADOR) - a Prospective, Multicentered, Single Arm Clinical Trial ARTHRITIS & RHEUMATOLOGY. 2016.10; 68

Hiroyuki Nakamura, Kenji Oku, Ryo Hisada, Kazumasa Ohmura, Masaru Kato, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, Shinsuke Yasuda, Tatsuya Atsumi: Complement Activation in Antiphospholipid Syndrome Due to the Multi-Activated Pathways of the Complement System ARTHRITIS & RHEUMATOLOGY. 2016.10; 68

Simone Mader, Yoshiyuki Arinuma, Venkatesh Jeganathan, Yuichiro Fujieda, Irena Dujmovi, Jelen Drulovic, Yuko Sakuma, Shinsuke Yasuda, Joel Stern, Cynthia Aranow, Meggan Mackay, Tatsuya Atsumi, Shunsei Hirohata, Betty Diamond: Clinical Utility of Anti-Aquaporin 4 Antibody Measurement in Patients with Neuropsychiatric Systemic Lupus Erythematosus with Neuromyelitis Optica Spectrum Disorder Manifestations ARTHRITIS & RHEUMATOLOGY. 2016.10; 68

Kenji Oku, Olga Amengual, Kazumasa Ohmura, Masaru Kato, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Eriko Morishita, Masahiro Ieko, Tatsuya Atsumi: A Practical Application of Antiphospholipid Antibodies Profiles in the Diagnosis and Managements of Antiphospholipid Syndrome: The Modified Antiphospholipid Score ARTHRITIS & RHEUMATOLOGY. 2016.10; 68

Kenji Oku, Uhei Shibata, Joana Batuca, Olga Amengual, Michihiro Kono, Hiroyuki Nakamura, Ryo Hisada, Kazumasa Ohmura, Masaru Kato, Toshiyuki Bohgaki, Shinsuke Yasuda, Jose Delgado Alves, Tatsuya Atsumi: Autoantibodies Against High Density Lipoprotein-Associated Proteins Are Related to Elevated Oxidized Low Density Lipoprotein Levels in Antiphospholipid Syndrome ARTHRITIS & RHEUMATOLOGY. 2016.10; 68

Ryo Hisada, Masaru Kato, Hisako Nakagawa, Eri Sugawara, Masatoshi Kanda, Kazumasa Ohmura, Ikuma Nakagawa, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, Shinsuke Yasuda, Tatsuya Atsumi: Deviation of T and B Cell Subset and Its Association with Single Nucleotide Polymorphisms in Patients with Antiphospholipid Syndrome ARTHRITIS & RHEUMATOLOGY. 2016.10; 68

Kazumasa Ohmura, Masaru Kato, Toshiyuki Watanabe, Ryo Hisada, Masatoshi Kanda, Sanae Shimamura, Ikuma Nakagawa, Yuka Shimizu, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, Shinsuke Yasuda, Tatsuya Atsumi: Preventive Effect of Combined Treatment with Bisphosphonate and Vitamin D on Atherosclerosis in Patients with Systemic Lupus Erythematosus ARTHRITIS & RHEUMATOLOGY. 2016.10; 68

Atsushi Noguchi, Shinsuke Yasuda, Ryo Hisada, Kazumasa Ohmura, Sanae Shimamura, Yuka Shimizu, Masaru Kato, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, Miho Suzuki, Yoshihiro Matsumoto, Tatsuya Atsumi: Anti-CCP Antibody Titers Decrease with Altered B-Cell Subpopulation in RA Patients Treated with Tocilizumab ARTHRITIS & RHEUMATOLOGY. 2016.10; 68

Otomo K, Amengual O, Fujieda Y, Nakagawa H, Kato M, Oku K, Horita T, Yasuda S, Matsumoto M, Nakayama KI, Hatakeyama S, Koike T, Atsumi T: Role of apolipoprotein B100 and oxidized low-density lipoprotein in the monocyte tissue factor induction mediated by anti-β2 glycoprotein I antibodies. Lupus. 2016.10; 25 (12): 1288-1298. ( PubMed , DOI )

Masaru Kato, Caroline Ospelt, Christoph Kolling, Tomohiro Shimizu, Michihito Kono, Shinsuke Yasuda, Beat A. Michel, Renate E. Gay, Steffen Gay, Kerstin Klein, Tatsuya Atsumi: AAA-ATPase p97 suppresses apoptotic and autophagy-associated cell death in rheumatoid arthritis synovial fibroblasts ONCOTARGET. 2016.09; 7 (39): 64221-64232. ( PubMed , DOI )

Yuka Shimizu, Shinsuke Yasuda, Yuki Kako, Shin Nakagawa, Masatoshi Kanda, Ryo Hisada, Kazumasa Ohmura, Sanae Shimamura, Haruki Shida, Yuichiro Fujieda, Masaru Kato, Kenji Oku, Toshiyuki Bohgaki, Tetsuya Horita, Ichiro Kusumi, Tatsuya Atsumi: Post-steroid neuropsychiatric manifestations are significantly more frequent in SLE compared with other systemic autoimmune diseases and predict better prognosis compared with de novo neuropsychiatric SLE AUTOIMMUNITY REVIEWS. 2016.08; 15 (8): 786-794. ( PubMed , DOI )

Kenji Oku, Olga Amengual, Ryo Hisada, Kazumasa Ohmura, Ikuma Nakagawa, Toshiyuki Watanabe, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Tatsuya Atsumi: Autoantibodies against a complement component 1 q subcomponent contribute to complement activation and recurrent thrombosis/pregnancy morbidity in anti-phospholipid syndrome RHEUMATOLOGY. 2016.08; 55 (8): 1403-1411. ( PubMed , DOI )

T. Bohgaki, S. Yasuda, M. Kato, K. Oku, O. Amengual, T. Horita, T. Atsumi: INDUCTION OF TYPE-I INTERFERON MRNA IN HUMAN CD14+CELLS TREATED WITH NEUTROPHIL EXTRACELLULAR TRAPS CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2016.07; 34 (4): S42.

Yuichiro Fujieda, Olga Amengual, Masaki Matsumoto, Kimiko Kuroki, Hidehisa Takahashi, Michihito Kono, Takashi Kurita, Kotaro Otomo, Masaru Kato, Kenji Oku, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Katsumi Maenaka, Shigetsugu Hatakeyama, Keiichi I. Nakayama, Tatsuya Atsumi: Ribophorin II is involved in the tissue factor expression mediated by phosphatidylserine-dependent antiprothrombin antibody on monocytes RHEUMATOLOGY. 2016.06; 55 (6): 1117-1126. ( PubMed , DOI )

H Takada, T Hosoya, N Kimura, K Kawahata, H Kohsaka: Successful use of rituximab in a patient with refractory thrombotic thrombocytopaenic purpura complicated by polymyositis. Scand. J. Rheumatol.. 2016.06; 1-2. ( PubMed , DOI )

Yoko Yoshihashi-Nakazato, Kimito Kawahata, Naoki Kimura, Nobuyuki Miyasaka, Hitoshi Kohsaka: Interferon-γ, but Not Interleukin-4, Suppresses Experimental Polymyositis. Arthritis & rheumatology (Hoboken, N.J.). 2016.06; 68 (6): 1505-1510. ( PubMed , DOI )

R. Hisada, M. Kato, E. Sugawara, K. Ohmura, I. Nakagawa, K. Oku, T. Bohgaki, O. Amengual, T. Horita, S. Yasuda, T. Atsumi: THROMBOCYTOPENIA IN PATIENTS WITH ANTIPHOSPHOLIPID ANTIBODIES: A PARADOXICAL THROMBOTIC RISK FACTOR ANNALS OF THE RHEUMATIC DISEASES. 2016.06; 75 315. ( DOI )

Y Tagawa, T Saito, K Takada, K Kawahata, H Kohsaka: Successful treatment of severe refractory lupus hepatitis with mycophenolate mofetil. Lupus. 2016.04; 25 (5): 543-546. ( PubMed , DOI )

Masayoshi Harigai, Toshihiro Nanki, Ryuji Koike, Michi Tanaka, Kaori Watanabe-Imai, Yukiko Komano, Ryoko Sakai, Hayato Yamazaki, Takao Koike, Nobuyuki Miyasaka: Risk for malignancy in rheumatoid arthritis patients treated with biological disease-modifying antirheumatic drugs compared to the general population: A nationwide cohort study in Japan. Mod Rheumatol. 2016.03; 1-9. ( PubMed , DOI )

Yusuke Matsuo, Fumitaka Mizoguchi, Tetsuya Saito, Kimito Kawahata, Satoshi Ueha, Kouji Matsushima, Yutaka Inagaki, Nobuyuki Miyasaka, Hitoshi Kohsaka: Local fibroblast proliferation but not influx is responsible for synovial hyperplasia in a murine model of rheumatoid arthritis. Biochem. Biophys. Res. Commun.. 2016.02; 470 (3): 504-509. ( PubMed , DOI )

Tadashi Hosoya, Hideyuki Iwai, Yu Yamaguchi, Kimito Kawahata, Nobuyuki Miyasaka, Hitoshi Kohsaka: Cell cycle regulation therapy combined with cytokine blockade enhances antiarthritic effects without increasing immune suppression. Ann. Rheum. Dis.. 2016.01; 75 (1): 253-259. ( PubMed , DOI )

Tatsuya Atsumi, Kazuhiko Yamamoto, Tsutomu Takeuchi, Hisashi Yamanaka, Naoki Ishiguro, Yoshiya Tanaka, Katsumi Eguchi, Akira Watanabe, Hideki Origasa, Shinsuke Yasuda, Yuji Yamanishi, Yasuhiko Kita, Tsukasa Matsubara, Masahiro Iwamoto, Toshiharu Shoji, Toshiyuki Okada, Desiree van der Heijde, Nobuyuki Miyasaka, Takao Koike: The first double-blind, randomised, parallel-group certolizumab pegol study in methotrexate-naive early rheumatoid arthritis patients with poor prognostic factors, C-OPERA, shows inhibition of radiographic progression ANNALS OF THE RHEUMATIC DISEASES. 2016.01; 75 (1): 75-83. ( PubMed , DOI )

Mineto Ota, Hideyuki Iwai, Kaori Imai, Mari Kamiya, Yoko Yoshihashi-Nakazato, Nobuyuki Miyasaka, Hitoshi Kohsaka: Acute Tubulointerstitial Nephritis Associated with Infliximab in a Patient with Crohn's Disease. Intern. Med.. 2016; 55 (10): 1367-1370. ( PubMed , DOI )

Tatsuya Kawasaki, Mari Kamiya, Atsushi Nakagawa, Jun Takagiwa, Yutaka Kawahara, Yoshinori Nonomura: Allergic bronchopulmonary aspergillosis in a patient with rheumatoid arthritis under adalimumab therapy: a case report Nihon Rinsho Meneki Gakkai Kaishi. 2016; 39 (1): 84-89. ( PubMed )

Mari Kamiya, Peter Y Shane, Makoto Soejima, Shuji Tohda, Nobuyuki Miyasaka, Hitoshi Kohsaka: IgG4-Related Sialoadenitis with a Skin Lesion and Multiple Mononeuropathies Suggesting Coexistent Cryoglobulinemic Vasculitis. Intern. Med.. 2016; 55 (10): 1355-1361. ( PubMed , DOI )

Ota M, Iwai H, Imai K, Kamiya M, Yoshihashi-Nakazato Y, Miyasaka N, Kohsaka H: Acute Tubulointerstitial Nephritis Associated with Infliximab in a Patient with Crohn's Disease Intern Med.. 2016; 55 (10): 1367-1370.

Shinsuke Yasuda: Antiphospholipid Antibodies as a Thrombotic Risk Factor in Connective Tissue Diseases and Idiopathic/immune Thrombocytopenic Purpura - Proposal for Altered Cut-off values for Better Prediction INTERNAL MEDICINE. 2016; 55 (6): 557-558. ( PubMed , DOI )

Ryoko Sakai, Fumio Hirano, Mari Kihara, Waka Yokoyama, Hayato Yamazaki, Sayoko Harada, Toshihiro Nanki, Ryuji Koike, Nobuyuki Miyasaka, Masayoshi Harigai: High prevalence of cardiovascular comorbidities in patients with rheumatoid arthritis from a population-based cross-sectional study of a Japanese health insurance database. Mod Rheumatol. 2015.12; 1-7. ( PubMed , DOI )

Kenji Oku, Olga Amengual, Hiroyuki Nakamura, Ryo Hisada, Kazumasa Oomura, Masaru Mato, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Tatsuya Atsumi: Markers of thrombotic events in autoimmune diseases: Comparison of Antiphospholipid Score (aPL-S) and Global Anti-phospholipid Syndrome Score (GAPSS) JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2015.11; 112 129-130. ( DOI )

Takumi Matsumoto, Tetsuya Saito, Hitoshi Kohsaka: A case of chronic myelomonocytic leukemia complicated with spondyloarthritis. Mod Rheumatol. 2015.10; 1-3. ( PubMed , DOI )

Kenji Oku, Yusaku Kanetsuka, Olga Amengual, Hiroyuki Nakamura, Kazumasa Oomura, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Bas Delaat, Tatsuya Atsumi: Procoagulant Property of a Novel Patient-Derived Autoimmune IgG Type Monoclonal Anticardiolipin Antibody That Binds to Beta 2 Glycoprotein Domain I but Not to Total Beta 2 Glycoprotein I Molecule ARTHRITIS & RHEUMATOLOGY. 2015.10; 67

Toshiyuki Watanabe, Kenji Oku, Olga Amengual, Ryo Hisada, Kazumasa Ohmura, Haruki Shida, Yuka Shimizu, Masaru Kato, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Akihiro Ishizu, Hisashi Arase, Tatsuya Atsumi: Reduction of HLA Class II Expression and Beta-2-Glycoprotein I Presentation By Fluvastatin in Vitro and in Vivo: Possible Mechanism of Statin-Induced-Deprocoagulation in the Antiphospholipid Syndrome ARTHRITIS & RHEUMATOLOGY. 2015.10; 67

Masaru Kato, Kerstin Klein, Caroline Ospelt, Christoph Kolling, Michihito Kono, Shinsuke Yasuda, Renate E. Gay, Steffen Gay, Tatsuya Atsumi: AAA-Atpase p97-HDAC6 Controlled Poly-Ubiquitin Turnover Regulates Apoptotic and Autophagy-Associated Cell Death in Arthritis ARTHRITIS & RHEUMATOLOGY. 2015.10; 67

Michi Tanaka, Ryoko Sakai, Ryuji Koike, Masayoshi Harigai: Pneumocystis Jirovecii Pneumonia in Japanese Patients with Rheumatoid Arthritis Treated with Tumor Necrosis Factor Inhibitors: A Pooled Analysis of 3 Agents. J. Rheumatol.. 2015.09; 42 (9): 1726-1728. ( PubMed , DOI )

Takehiro Yamada, Nobuhisa Ishiguro, Kenji Oku, Issei Higuchi, Ikuma Nakagawa, Atsushi Noguchi, Shinsuke Yasuda, Tatsuya Fukumoto, Sumio Iwasaki, Kouji Akizawa, Ayako Furugen, Hiroaki Yamaguchi, Ken Iseki: Successful Colistin Treatment of Multidrug-Resistant Pseudomonas aeruginosa Infection Using a Rapid Method for Determination of Colistin in Plasma: Usefulness of Therapeutic Drug Monitoring BIOLOGICAL & PHARMACEUTICAL BULLETIN. 2015.09; 38 (9): 1430-1433. ( PubMed , DOI )

Hosoya Tadashi, Mizoguchi Fumitaka, Hasegawa Hisanori, Miura Keiko, Koike Ryuji, Kubota Tetsuo, Miyasaka Nobuyuki, Kohsaka Hitoshi: TNFRSF1A遺伝子変異を認めず、トシリズマブ投与が奏効した、腫瘍壊死因子(TNF)受容体関連周期性症候群(TRAPS)の臨床的特徴を示す1症例(A Case Presenting with the Clinical Characteristics of Tumor Necrosis Factor(TNF) Receptor-associated Periodic Syndrome(TRAPS) without TNFRSF1A Mutations Successfully Treated with Tocilizumab) Internal Medicine. 2015.08; 54 (16): 2069-2072. ( ichushi )

Michihito Kono, Shinsuke Yasuda, Toshiyuki Watanabe, Tatsuya Atsumi: Projectile haemorrhage of a brachial artery in a patient with clinically amyopathic dermatomyositis RHEUMATOLOGY. 2015.08; 54 (8): 1530-1531. ( PubMed , DOI )

Takashi Kurita, Shinsuke Yasuda, Koji Oba, Toshio Odani, Michihito Kono, Kotaro Otomo, Yuichiro Fujieda, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, Tatsuya Atsumi: The efficacy of tacrolimus in patients with interstitial lung diseases complicated with polymyositis or dermatomyositis. Rheumatology (Oxford, England). 2015.08; 54 (8): 1536. ( PubMed , DOI )

Okiyama Naoko, Hasegawa Hisanori, Oida Takatoku, Hirata Shinya, Yokozeki Hiroo, Fujimoto Manabu, Miyasaka Nobuyuki, Kohsaka Hitoshi: Experimental myositis inducible with transfer of dendritic cells presenting a skeletal muscle C protein-derived CD8 epitope peptide INTERNATIONAL IMMUNOLOGY. 2015.07; 27 (7): 327-332. ( PubMed , DOI )

Shinsuke Yasuda, Takashi Kurita, Tetsuya Horita, Tatsuya Atsumi: Comment on: The efficacy of tacrolimus in patients with interstitial lung diseases complicated with polymyositis or dermatomyositis: reply RHEUMATOLOGY. 2015.06; 54 (6): 1129. ( PubMed , DOI )

K. Oku, O. Amengual, T. Bohgaki, T. Horita, S. Yasuda, T. Atsumi: An independent validation of the Global Anti-Phospholipid Syndrome Score in a Japanese cohort of patients with autoimmune diseases LUPUS. 2015.06; 24 (7): 774-775. ( PubMed , DOI )

M. Kato, K. Klein, C. Ospelt, C. Kolling, M. Kono, S. Yasuda, R. E. Gay, S. Gay, T. Atsumi: AAA-ATPASE P97 REGULATES APOPTOTIC AND AUTOPHAGY-ASSOCIATED CELL DEATH IN ARTHRITIS ANNALS OF THE RHEUMATIC DISEASES. 2015.06; 74 207-208. ( DOI )

K. Oku, O. Amengual, R. Hisada, K. Oomura, Nakagawa, I, T. Watanabe, T. Bohgaki, T. Horita, S. Yasuda, T. Atsumi: Predictive markers for thrombotic events in autoimmune diseases: comparison of antiphospholipid score (APL-S) and global anti-phospholipid syndrome score (GAPSS) JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2015.06; 13 775.

A. Noguchi, S. Yasuda, M. Kono, M. Kato, K. Oku, T. Bohgaki, O. Amengual, T. Horita, T. Sato, I. Tsujino, M. Nishimura, T. Atsumi: CARDIAC MAGNETIC RESONANCE IMAGING DETECTS DISEASE-SPECIFIC BIVENTRICULAR INVOLVEMENT IN PATIENTS WITH SYSTEMIC SCLEROSIS-ASSOCIATED PULMONARY ARTERIAL HYPERTENSION ANNALS OF THE RHEUMATIC DISEASES. 2015.06; 74 1124. ( DOI )

Takahiko Sugihara, Tatsuro Ishizaki, Tadashi Hosoya, Shoko Iga, Waka Yokoyama, Fumio Hirano, Nobuyuki Miyasaka, Masayoshi Harigai: Structural and functional outcomes of a therapeutic strategy targeting low disease activity in patients with elderly-onset rheumatoid arthritis: a prospective cohort study (CRANE). Rheumatology (Oxford). 2015.05; 54 (5): 798-807. ( PubMed , DOI )

S. Yasuda, Y. Shimizu, M. Kono, S. Shimamura, A. Noguchi, H. Shida, T. Watanabe, M. Kato, K. Oku, T. Bohgaki, O. Amengual, T. Horita, T. Atsumi: Myxovirus resistance protein 1 (Mx1) levels are elevated in T cells of the patients with SLE and serum Mx1 is a marker of Neuropsychiatric SLE CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2015.05; 33 (3): S20.

Hayato Yamazaki, Ryoko Sakai, Ryuji Koike, Yasunari Miyazaki, Michi Tanaka, Toshihiro Nanki, Kaori Watanabe, Shinsuke Yasuda, Takashi Kurita, Yuko Kaneko, Yoshiya Tanaka, Yasuhiko Nishioka, Yoshinari Takasaki, Kenji Nagasaka, Hayato Nagasawa, Shigeto Tohma, Makoto Dohi, Takahiko Sugihara, Haruhito Sugiyama, Yasushi Kawaguchi, Naohiko Inase, Sae Ochi, Hiroyuki Hagiyama, Hitoshi Kohsaka, Nobuyuki Miyasaka, Masayoshi Harigai, : Assessment of risks of pulmonary infection during 12 months following immunosuppressive treatment for active connective tissue diseases: a large-scale prospective cohort study. J. Rheumatol.. 2015.04; 42 (4): 614-622. ( PubMed , DOI )

Kuwata Yusuke, Tanimoto Shina, Sawabe Etsuko, Shima Mari, Takahashi Yutaka, Ushizawa Hiroto, Fujie Toshihide, Koike Ryuji, Tojo Naoko, Kubota Tetsuo, Saito Ryoichi: Molecular epidemiology and antimicrobial susceptibility of Clostridium difficile isolated from a university teaching hospital in Japan. Eur J Clin Microbiol Infect Dis. 2015.04; 34 (4): 763-772. ( PubMed , DOI )

Naoki Kimura, Shinya Hirata, Nobuyuki Miyasaka, Kimito Kawahata, Hitoshi Kohsaka: Injury and subsequent regeneration of muscles for activation of local innate immunity to facilitate the development and relapse of autoimmune myositis in C57BL/6 mice. Arthritis & rheumatology (Hoboken, N.J.). 2015.04; 67 (4): 1107-1116. ( PubMed , DOI )

Tanimura K, Jin H, Suenaga T, Morikami S, Arase N, Kishida K, Hirayasu K, Kohyama M, Ebina Y, Yasuda S, Horita T, Takasugi K, Ohmura K, Yamamoto K, Katayama I, Sasazuki T, Lanier LL, Atsumi T, Yamada H, Arase H: β2-glycoprotein I / HLA class II complexes are novel autoantigens in antiphospholipid syndrome. Blood. 2015.04; 125 (18): 2835-2844. ( PubMed , DOI )

Michihito Kono, Shinsuke Yasuda, Richard L. Stevens, Hideyuki Koide, Takashi Kurita, Yuka Shimizu, Yusaku Kanetsuka, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, Tomohiro Shimizu, Tokifumi Majima, Takao Koike, Tatsuya Atsumi: Ras Guanine Nucleotide-Releasing Protein 4 Is Aberrantly Expressed in the Fibroblast-like Synoviocytes of Patients With Rheumatoid Arthritis and Controls Their Proliferation ARTHRITIS & RHEUMATOLOGY. 2015.02; 67 (2): 396-407. ( PubMed , DOI )

Kanako Watanabe, Shinsuke Yasuda, Atsushi Noguchi, Tetsuya Horita, Tatsuya Atsumi: Clinical Images: Coronary and mesenteric involvement in polyarteritis nodosa ARTHRITIS & RHEUMATOLOGY. 2015.02; 67 (2): 583. ( PubMed , DOI )

Hiroshi Kataoka, Shinsuke Yasuda, Shinji Fukaya, Kenji Oku, Tetsuya Horita, Tatsuya Atsumi, Takao Koike: Decreased expression of Runx1 and lowered proportion of Foxp3(+)CD25(+)CD4(+) regulatory T cells in systemic sclerosis MODERN RHEUMATOLOGY. 2015.01; 25 (1): 90-95. ( PubMed , DOI )

T. Kurita, S. Yasuda, O. Amengual, T. Atsumi: The efficacy of calcineurin inhibitors for the treatment of interstitial lung disease associated with polymyositis/dermatomyositis LUPUS. 2015.01; 24 (1): 3-9. ( PubMed , DOI )

Kurita T, Yasuda S, Oba K, Odani T, Kono M, Otomo K, Fujieda Y, Oku K, Bohgaki T, Amengual O, Horita T, Atsumi T: The efficacy of tacrolimus in patients with interstitial lung diseases complicated with polymyositis or dermatomyositis. Rheumatology (Oxford, England). 2015.01; 54 (1): 39-44. ( PubMed , DOI )

Ryoko Sakai, Soo-Kyung Cho, Toshihiro Nanki, Kaori Watanabe, Hayato Yamazaki, Michi Tanaka, Ryuji Koike, Yoshiya Tanaka, Kazuyoshi Saito, Shintaro Hirata, Koichi Amano, Hayato Nagasawa, Takayuki Sumida, Taichi Hayashi, Takahiko Sugihara, Hiroaki Dobashi, Shinsuke Yasuda, Tetsuji Sawada, Kazuhiko Ezawa, Atsuhisa Ueda, Takao Fujii, Kiyoshi Migita, Nobuyuki Miyasaka, Masayoshi Harigai, : Head-to-head comparison of the safety of tocilizumab and tumor necrosis factor inhibitors in rheumatoid arthritis patients (RA) in clinical practice: results from the registry of Japanese RA patients on biologics for long-term safety (REAL) registry. Arthritis Res. Ther.. 2015; 17 74. ( PubMed , DOI )

Tadashi Hosoya, Fumitaka Mizoguchi, Hisanori Hasegawa, Keiko Miura, Ryuji Koike, Tetsuo Kubota, Nobuyuki Miyasaka, Hitoshi Kohsaka: A Case Presenting with the Clinical Characteristics of Tumor Necrosis Factor (TNF) Receptor-associated Periodic Syndrome (TRAPS) without TNFRSF1A Mutations Successfully Treated with Tocilizumab. Intern. Med.. 2015; 54 (16): 2069-2072. ( PubMed , DOI )

Shinsuke Yasuda, Tatsuya Atsumi, Sanae Shimamura, Kota Ono, Keiju Hiromura, Kenei Sada, Masaaki Mori, Syuji Takei, Yasushi Kawaguchi, Naoto Tamura, Yoshinari Takasaki: Surveillance for the use of mycophenolate mofetil for adult patients with lupus nephritis in Japan MODERN RHEUMATOLOGY. 2015; 25 (6): 854-857. ( DOI )

Ryoki Hara, Hirotaka Miyazawa, Kenichi Nishimura, Takahiro Momoi, Tomo Nozawa, Masako Kikuchi, Nodoka Sakurai, Toshitaka Kizawa, Sanae Shimamura, Shinsuke Yasuda, Keiju Hiromura, Ken-ei Sada, Yasushi Kawaguchi, Naoto Tamura, Syuji Takei, Yoshinari Takasaki, Tatsuya Atsumi, Masaaki Mori: A national survey on current use of mycophenolate mofetil for childhood-onset systemic lupus erythematosus in Japan MODERN RHEUMATOLOGY. 2015; 25 (6): 858-864. ( PubMed , DOI )

Michi Tanaka, Ryuji Koike, Ryoko Sakai, Kazuyoshi Saito, Shintaro Hirata, Hayato Nagasawa, Hideto Kameda, Masako Hara, Yasushi Kawaguchi, Shigeto Tohma, Yoshinari Takasaki, Makoto Dohi, Yasuhiko Nishioka, Shinsuke Yasuda, Yasunari Miyazaki, Yuko Kaneko, Toshihiro Nanki, Kaori Watanabe, Hayato Yamazaki, Nobuyuki Miyasaka, Masayoshi Harigai: Pulmonary infections following immunosuppressive treatments during hospitalization worsen the short-term vital prognosis for patients with connective tissue disease-associated interstitial pneumonia. Mod Rheumatol. 2014.12; 1-6. ( PubMed , DOI )

Ryoko Sakai, Soo-Kyung Cho, Toshihiro Nanki, Ryuji Koike, Kaori Watanabe, Hayato Yamazaki, Hayato Nagasawa, Koichi Amano, Yoshiya Tanaka, Takayuki Sumida, Atsushi Ihata, Shinsuke Yasuda, Atsuo Nakajima, Takahiko Sugihara, Naoto Tamura, Takao Fujii, Hiroaki Dobashi, Yasushi Miura, Nobuyuki Miyasaka, Masayoshi Harigai, : The risk of serious infection in patients with rheumatoid arthritis treated with tumor necrosis factor inhibitors decreased over time: a report from the registry of Japanese rheumatoid arthritis patients on biologics for long-term safety (REAL) database. Rheumatol. Int.. 2014.12; 34 (12): 1729-1736. ( PubMed , DOI )

Yuka Shimizu, Shinsuke Yasuda, Takashi Kurita, Sanae Shimamura, Ikuma Nakagawa, Atsushi Noguchi, Haruki Shida, Toshiyuki Watanabe, Michihito Kono, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, Tatsuya Atsumi: Upregulation of Myxovirus Resistance Protein 1 in Patients with Neuropsychiatric Systemic Lupus Erythematosus ARTHRITIS & RHEUMATOLOGY. 2014.10; 66 S718-S719. ( DOI )

Tomoko Fukui, Shinsuke Yasuda, Toshiyuki Watanabe, Kazumasa Ohmura, Sanae Shimamura, Ikuma Nakagawa, Atsushi Noguchi, Haruki Shida, Yuka Shimizu, Michihito Kono, Takashi Kurita, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, Tatsuya Atsumi: Antiphospholipid-Associated Nephropathy Is a Risk for Developing Arterial Thromboses in Patients with Systemic Lupus Erythematosus ARTHRITIS & RHEUMATOLOGY. 2014.10; 66 S3.

Toshiyuki Watanabe, Kenji Oku, Olga Amengual, Eri Sugawara, Ryo Hisada, Kazumasa Ohmura, Tomoko Fukui, Sanae Shimamura, Ikuma Nakagawa, Atsushi Noguchi, Haruki Shida, Michihito Kono, Yuka Shimizu, Takashi Kurita, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Tatsuya Atsumi: The Protective Effects of Statins for Thrombosis in Patients with Systemic Lupus Erythematosus Positive for Antiphospholipid Antibodies. ARTHRITIS & RHEUMATOLOGY. 2014.10; 66 S1154-S1155.

Michihito Kono, Shinsuke Yasuda, Kazumasa Ohmura, Tomoko Fukui, Sanae Shimamura, Ikuma Nakagawa, Atsushi Noguchi, Haruki Shida, Toshiyuki Watanabe, Yuka Shimizu, Takashi Kurita, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, Keita Sakamoto, Tamotsu Kamishima, Tatsuya Atsumi: Efficacy of Tocilizumab in Patients with Rheumatoid Arthritis: Sequential Evaluation Using Whole-Body Magnetic Resonance Imaging. ARTHRITIS & RHEUMATOLOGY. 2014.10; 66 S518. ( DOI )

Kenji Oku, Olga Amengual, Ryo Hisada, Kazumasa Oomura, Ikuma Nakagawa, Toshiyuki Watanabe, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Tatsuya Atsumi: Markers of Thrombotic Events in Autoimmune Diseases: Comparison of Antiphospholipid Score (aPL-S) and Global Anti-Phospholipid Syndrome Score (GAPSS). ARTHRITIS & RHEUMATOLOGY. 2014.10; 66 S1251-S1252.

Masaru Kato, Kerstin Klein, Caroline Ospelt, Christoph Kolling, Michihito Kono, Shinsuke Yasuda, Renate E. Gay, Steffen Gay, Tatsuya Atsumi: AAA-Atpase p97 Regulates Autophagy-Associated Cell Death in Arthritis ARTHRITIS & RHEUMATOLOGY. 2014.10; 66 S195.

Takashi Kurita, Shinsuke Yasuda, Vaishali Moulton, Yuka Shimizu, Michihito Kono, Hideyuki Koide, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, George C. Tsokos, Tatsuya Atsumi: Decreased Levels of SRSF1 (Serin/Arginine-Rich Splicing Factor1) Induced Lower Levels of RasGRP1 in T Cells from Patients with Systemic Lupus Erythematosus. ARTHRITIS & RHEUMATOLOGY. 2014.10; 66 S1171.

Ikuma Nakagawa, Kenji Oku, Olga Amengual, Ryo Hisada, Eri Sugawara, Kazumasa Ohmura, Tomoko Fukui, Sanae Shimamura, Haruki Shida, Toshiyuki Watanabe, Yuka Shimizu, Michihito Kono, Takashi Kurita, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Tatsuya Atsumi: Thrombocytopenia in Primary Antiphospholipid Syndrome Is Related to Arterial Thrombosis ARTHRITIS & RHEUMATOLOGY. 2014.10; 66 S1.

M. Kono, S. Yasuda, M. Kato, Y. Kanetsuka, T. Kurita, Y. Fujieda, K. Otomo, T. Horita, K. Oba, M. Kondo, M. Mukai, M. Yanai, Y. Fukasawa, T. Atsumi: Long-term outcome in Japanese patients with lupus nephritis LUPUS. 2014.10; 23 (11): 1124-1132. ( PubMed , DOI )

Olga Amengual, Tetsuya Horita, Walter Binder, Gary L. Norman, Zakera Shums, Masaru Kato, Kotaro Otomo, Yuichiro Fujieda, Kenji Oku, Toshiyuki Bohgaki, Shinsuke Yasuda, Tatsuya Atsumi: Comparative analysis of different enzyme immunoassays for assessment of phosphatidylserine-dependent antiprothrombin antibodies RHEUMATOLOGY INTERNATIONAL. 2014.09; 34 (9): 1225-1230. ( PubMed , DOI )

Soo-Kyung Cho, Ryoko Sakai, Toshihiro Nanki, Ryuji Koike, Kaori Watanabe, Hayato Yamazaki, Hayato Nagasawa, Yoshiya Tanaka, Atsuo Nakajima, Shinsuke Yasuda, Atsushi Ihata, Kazuhiko Ezawa, Soyoung Won, Chan-Bum Choi, Yoon-Kyoung Sung, Tae-Hwan Kim, Jae-Bum Jun, Dae-Hyun Yoo, Nobuyuki Miyasaka, Sang-Cheol Bae, Masayoshi Harigai, , : A comparison of incidence and risk factors for serious adverse events in rheumatoid arthritis patients with etanercept or adalimumab in Korea and Japan. Mod Rheumatol. 2014.07; 24 (4): 572-579. ( PubMed , DOI )

Natsuka Umezawa, Hitoshi Kohsaka, Toshihiro Nanki, Kaori Watanabe, Michi Tanaka, Peter Y Shane, Nobuyuki Miyasaka: Successful treatment of eosinophilic granulomatosis with polyangiitis (EGPA; formerly Churg-Strauss syndrome) with rituximab in a case refractory to glucocorticoids, cyclophosphamide, and IVIG. Modern Rheumatolgy. 2014.07; 24 (4): 685-687. ( PubMed , DOI )

Satoka Shimogaki, Sayaka Ito, Sachiyo Komatsu, Ryuji Koike, Nobuyuki Miyasaka, Kazuo Umezawa, Tetsuo Kubota: Inhibition of the NF-κB pathway as a candidate therapeutic strategy for cryopyrin-associated periodic syndrome. Mod Rheumatol. 2014.05; 24 (3): 517-524. ( PubMed , DOI )

Saito R, Takahashi R, Sawabe E, Koyano S, Takahashi Y, Shima M, Ushizawa H, Fujie T, Tosaka N, Kato Y, Moriya K, Tohda S, Tojo N, Koike R, Kubota T: First Report of KPC-2 Carbapenemase-Producing Klebsiella pneumoniae in Japan. Antimicrob Agents Chemother. 2014.05; 58 (5): 2961-2963. ( PubMed , DOI )

Shin Fukuda, Toshihiro Nanki, Tomohiro Morio, Hisanori Hasegawa, Ryuji Koike, Nobuyuki Miyasaka: Recurrent mitral valve regurgitation with neutrophil infiltration in a patient with multiple aseptic abscesses. Mod Rheumatol. 2014.05; 24 (3): 537-539. ( PubMed , DOI )

Hui Jin, Noriko Arase, Kouyuki Hirayasu, Masako Kohyama, Tadahiro Suenaga, Fumiji Saito, Kenji Tanimura, Sumiko Matsuoka, Kosuke Ebina, Kenrin Shi, Noriko Toyama-Sorimachi, Shinsuke Yasuda, Tetsuya Horita, Ryosuke Hiwa, Kiyoshi Takasugi, Koichiro Ohmura, Hideki Yoshikawa, Takashi Saito, Tatsuya Atsumi, Takehiko Sasazuki, Ichiro Katayama, Lewis L Lanier, Hisashi Arase: Autoantibodies to IgG/HLA class II complexes are associated with rheumatoid arthritis susceptibility. Proceedings of the National Academy of Sciences of the United States of America. 2014.03; 111 (10): 3787-92. ( PubMed , DOI )

Naoki Kimura, Kazuki Takada, Kiyoshi Murata, Hitoshi Kohsaka, Nobuyuki Miyasaka: A case of Behçet’s disease complicated by carotid-oesophageal fistula. Rheumatology (Oxford). 2014.01; 53 (1): 196-198. ( PubMed , DOI )

Kenji Nakagawa, Eva Gonzalez-Roca, Alejandro Souto, Toshinao Kawai, Hiroaki Umebayashi, Josep María Campistol, Jeronima Cañellas, Syuji Takei, Norimoto Kobayashi, Jose Luis Callejas-Rubio, Norberto Ortego-Centeno, Estíbaliz Ruiz-Ortiz, Fina Rius, Jordi Anton, Estibaliz Iglesias, Santiago Jimenez-Treviño, Carmen Vargas, Julian Fernandez-Martin, Inmaculada Calvo, José Hernández-Rodríguez, María Mendez, María Teresa Dordal, Maria Basagaña, Segundo Bujan, Masato Yashiro, Tetsuo Kubota, Ryuji Koike, Naoko Akuta, Kumiko Shimoyama, Naomi Iwata, Megumu K Saito, Osamu Ohara, Naotomo Kambe, Takahiro Yasumi, Kazushi Izawa, Tomoki Kawai, Toshio Heike, Jordi Yagüe, Ryuta Nishikomori, Juan I Aróstegui: Somatic NLRP3 mosaicism in Muckle-Wells syndrome. A genetic mechanism shared by different phenotypes of cryopyrin-associated periodic syndromes. Ann. Rheum. Dis.. 2013.12; ( PubMed , DOI )

Kaori Watanabe, Ryoko Sakai, Ryuji Koike, Fumikazu Sakai, Haruhito Sugiyama, Michi Tanaka, Yukiko Komano, Yuji Akiyama, Toshihide Mimura, Motohide Kaneko, Hitoshi Tokuda, Takenobu Iso, Mitsuru Motegi, Kei Ikeda, Hiroshi Nakajima, Hirofumi Taki, Tetsuo Kubota, Hirotaka Kodama, Shoji Sugii, Takashi Kuroiwa, Yasushi Nawata, Kazuko Shiozawa, Atsushi Ogata, Shigemasa Sawada, Yoshihiro Matsukawa, Takahiro Okazaki, Masaya Mukai, Mitsuhiro Iwahashi, Kazuyoshi Saito, Yoshiya Tanaka, Toshihiro Nanki, Nobuyuki Miyasaka, Masayoshi Harigai: Clinical characteristics and risk factors for Pneumocystis jirovecii pneumonia in patients with rheumatoid arthritis receiving adalimumab: a retrospective review and case-control study of 17 patients. Mod Rheumatol. 2013.11; 23 (6): 1085-1093. ( PubMed , DOI )

Mari Kihara, Takahiko Sugihara, Tadashi Hosoya, Nobuyuki Miyasaka: Clinical significance of complement as a biomarker of disease activity in 4 cases of IgG4-related disease with retroperitoneal fibrosis. Clin. Exp. Rheumatol.. 2013.11; 31 (6): 947-949. ( PubMed )

Fumitaka Mizoguchi, Yousuke Murakami, Tetsuya Saito, Nobuyuki Miyasaka, Hitoshi Kohsaka: miR-31 controls osteoclast formation and bone resorption by targeting RhoA. Arthritis Res. Ther.. 2013.11; 15 (5): R102. ( PubMed , DOI )

M. Kato, T. Atsumi, K. Oku, O. Amengual, H. Nakagawa, Y. Fujieda, K. Otomo, T. Horita, S. Yasuda, T. Koike: The involvement of CD36 in monocyte activation by antiphospholipid antibodies Lupus. 2013.07; 22 (8): 761-771. ( PubMed , DOI )

Toshihiro Nanki, Ikumi Onoue, Kenji Nagasaka, Aiko Takayasu, Masashi Ebisawa, Tadashi Hosoya, Toshizumi Shirai, Takahiko Sugihara, Shinya Hirata, Tetsuo Kubota, Masayoshi Harigai, Nobuyuki Miyasaka: Suppression of elevations in serum C reactive protein levels by anti-IL-6 autoantibodies in two patients with severe bacterial infections. Ann. Rheum. Dis.. 2013.06; 72 (6): 1100-1102. ( PubMed , DOI )

T. Watanabe, K. Oku, O. Amengual, S. Shimamura, I. Nakagawa, A. Noguchi, Y. Kanetsuka, M. Kono, T. Kurita, Y. Fujieda, T. Bohgaki, S. Yasuda, T. Horita, T. Atsumi: THE ANALYSIS OF RISK AND PROTECTIVE FACTORS FOR THROMBOSIS IN SYSTEMIC LUPUS ERYTHEMATOSUS WITH OR WITHOUT ANTIPHOSPHOLIPID ANTIBODIES ANNALS OF THE RHEUMATIC DISEASES. 2013.06; 72 482.

Hasegawa H., Mizoguchi F., Kohsaka H., Miyasaka N.: Systemic lupus erythematosus with cytophagic histiocytic panniculitis successfully treated with high-dose glucocorticoids and cyclosporine A LUPUS. 2013.03; 22 (3): 316-319. ( DOI )

Olga Amengual, Tatsuya Atsumi, Kenji Oku, Eriko Suzuki, Tetsuya Horita, Shinsuke Yasuda, Takao Koike: Phospholipid scramblase 1 expression is enhanced in patients with antiphospholipid syndrome Modern Rheumatology. 2013.01; 23 (1): 81-88. ( PubMed , DOI )

Shinsuke Yasuda: Disseminated intravascular coagulation in the presence of antiphospholipid antibodies: The differential diagnosis from catastrophic or microangiopathic antiphospholipid syndrome Internal Medicine. 2013; 52 (2): 169-170. ( PubMed , DOI )

Kenji Oku, Olga Amengual, Polona Zigon, Tetsuya Horita, Shinsuke Yasuda, Tatsuya Atsumi: Essential role of the p38 mitogen-activated protein kinase pathway in tissue factor gene expression mediated by the phosphatidylserine-dependent antiprothrombin antibody Rheumatology (United Kingdom). 2013; 52 (10): 1775-1784. ( PubMed , DOI )

Y. Fujieda, T. Atsumi, O. Amengual, T. Odani, K. Otomo, M. Kato, K. Oku, Y. Kon, T. Horita, S. Yasuda, T. Koike: Predominant prevalence of arterial thrombosis in Japanese patients with antiphospholipid syndrome LUPUS. 2012.12; 21 (14): 1506-1514. ( PubMed , DOI )

Michi Tanaka, Ryoko Sakai, Ryuji Koike, Yukiko Komano, Toshihiro Nanki, Fumikazu Sakai, Haruhito Sugiyama, Hidekazu Matsushima, Toshihisa Kojima, Shuji Ohta, Yoji Ishibe, Takuya Sawabe, Yasuhiro Ota, Kazuhisa Ohishi, Hajime Miyazato, Yoshinori Nonomura, Kazuyoshi Saito, Yoshiya Tanaka, Hayato Nagasawa, Tsutomu Takeuchi, Ayako Nakajima, Hideo Ohtsubo, Makoto Onishi, Yoshinori Goto, Hiroaki Dobashi, Nobuyuki Miyasaka, Masayoshi Harigai: Pneumocystis jirovecii pneumonia associated with etanercept treatment in patients with rheumatoid arthritis: a retrospective review of 15 cases and analysis of risk factors. Mod Rheumatol. 2012.11; 22 (6): 849-858. ( PubMed , DOI )

Ryoko Sakai, Michi Tanaka, Toshihiro Nanki, Kaori Watanabe, Hayato Yamazaki, Ryuji Koike, Hayato Nagasawa, Koichi Amano, Kazuyoshi Saito, Yoshiya Tanaka, Satoshi Ito, Takayuki Sumida, Atsushi Ihata, Yoshiaki Ishigatsubo, Tatsuya Atsumi, Takao Koike, Atsuo Nakajima, Naoto Tamura, Takao Fujii, Hiroaki Dobashi, Shigeto Tohma, Takahiko Sugihara, Yukitaka Ueki, Akira Hashiramoto, Atsushi Kawakami, Noboru Hagino, Nobuyuki Miyasaka, Masayoshi Harigai, : Drug retention rates and relevant risk factors for drug discontinuation due to adverse events in rheumatoid arthritis patients receiving anticytokine therapy with different target molecules. Ann. Rheum. Dis.. 2012.11; 71 (11): 1820-1826. ( PubMed , DOI )

Yousuke Murakami, Fumitaka Mizoguchi, Tetsuya Saito, Nobuyuki Miyasaka, Hitoshi Kohsaka: p16(INK4a) exerts an anti-inflammatory effect through accelerated IRAK1 degradation in macrophages. J. Immunol.. 2012.11; 189 (10): 5066-5072. ( PubMed , DOI )

Toshio Odani, Shinsuke Yasuda, Yuko Ota, Yuichiro Fujieda, Yujiro Kon, Tetsuya Horita, Yasushi Kawaguchi, Tatsuya Atsumi, Hisashi Yamanaka, Takao Koike: Up-regulated expression of HLA-DRB5 transcripts and high frequency of the HLA-DRB5*01:05 allele in scleroderma patients with interstitial lung disease RHEUMATOLOGY. 2012.10; 51 (10): 1765-1774. ( PubMed , DOI )

Sugihara Takahiko, Ishizaki Tatsuro, Hosoya Tadashi, Iga Shoko, Yokoyama Waka, Hirano Fumio, Miyasaka Nobuyuki, Harigai Masayoshi: Treat-to-Target Strategy Aiming At Achievement of Structural and Functional Remission in Patients with Active Elderly-Onset Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM. 2012.10; 64 (10): S161-S162.

Hasegawa Hisanori, Kohsaka Hitoshi, Takada Kazuki, Miyasaka Nobuyuki: Renal Involvement in Antimyeloperoxidase Antineutrophil Cytoplasmic Antibody-positive Granulomatosis with Polyangiitis with Chronic Hypertrophic Pachymeningitis JOURNAL OF RHEUMATOLOGY. 2012.10; 39 (10): 2053-2055. ( PubMed , DOI )

Hayato Yamazaki, Ryoko Sakai, Ryuji Koike, Yasunari Miyazaki, Michi Tanaka, Toshihiro Nanki, Kaori Watanabe, Shinsuke Yasuda, Takashi Kurita, Yuko Kaneko, Yoshiya Tanaka, Yasuhiko Nishioka, Yoshinari Takasaki, Kenji Nagasaka, Koichi Amano, Shigeto Tohma, Makoto Dohi, Takahiko Sugihara, Haruhito Sugiyama, Yasushi Kawaguchi, Naohiko Inase, Sae Ochi, Hiroyuki Hagiyama, Nobuyuki Miyasaka, Masayoshi Harigai: How to Assess Risks for Pulmonary Infection in Patients Receiving Immunosuppressive Treatment for Rheumatic Diseases? A Report From a Large-Scale Prospective Cohort Study. ARTHRITIS AND RHEUMATISM. 2012.10; 64 (10): S44.

T. Odani, S. Yasuda, M. Kono, T. Kurita, Y. Fujieda, K. Otomo, Y. Kon, T. Horita, T. Atsumi: EFFECTIVENESS OF AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR INTERSTITIAL LUNG DISEASES IN PATIENTS WITH SYSTEMIC SCLEROSIS ANNALS OF THE RHEUMATIC DISEASES. 2012.06; 71 241.

T. Kurita, S. Yasuda, K. Oba, K. Otomo, H. Shida, T. Watanabe, Y. Kanetsuka, M. Kono, T. Odani, Y. Fujieda, Y. Kon, T. Horita, N. Sato, T. Atsumi: THE EFFICACY OF TACROLIMUS IN PATIENTS WITH INTERSTITIAL LUNG DISEASES COMPLICATED WITH POLYMYOSITIS OR DERMATOMYOSITIS ANNALS OF THE RHEUMATIC DISEASES. 2012.06; 71 233.

Kotaro Otomo, Tatsuya Atsumi, Olga Amengual, Yuichiro Fujieda, Masaru Kato, Kenji Oku, Tetsuya Horita, Shinsuke Yasuda, Takao Koike: Efficacy of the antiphospholipid score for the diagnosis of antiphospholipid syndrome and its predictive value for thrombotic events ARTHRITIS AND RHEUMATISM. 2012.02; 64 (2): 504-512. ( PubMed , DOI )

Kato M., Kataoka H., Odani T., Fujieda Y., Otomo K., Oku K., Horita T., Yasuda S., Atsumi T., Ohira H., Tsujino I., Nishimura M., Koike T.: The short-term role of corticosteroid therapy for pulmonary arterial hypertension associated with connective tissue diseases: report of five cases and a literature review LUPUS. 2011.10; 20 (10): 1047-1056. ( DOI )

Kato Masaru, Atsumi Tatsuya, Kurita Takashi, Odani Toshio, Fujieda Yuichiro, Otomo Kotaro, Horita Tetsuya, Yasuda Shinsuke, Koike Takao: Hepatitis B Virus Reactivation by Immunosuppressive Therapy in Patients with Autoimmune Diseases: Risk Analysis in Hepatitis B Surface Antigen-negative Cases JOURNAL OF RHEUMATOLOGY. 2011.10; 38 (10): 2209-2214. ( DOI )

Yasuhiro Tagawa, Nobuhiko Hiramatsu, Hironori Kato, Takashi Sakoh, Shotaro Nakajima, Kunihiro Hayakawa, Yukinori Saito, Hisashi Johno, Shuhei Takahashi, Liubao Gu, Jian Yao, Masanori Kitamura: Induction of CCAAT/enhancer-binding protein-homologous protein by cigarette smoke through the superoxide anion-triggered PERK-eIF2α pathway. Toxicology. 2011.09; 287 (1-3): 105-112. ( PubMed , DOI )

Ryuji Koike, Michi Tanaka, Yukiko Komano, Fumikazu Sakai, Haruhito Sugiyama, Toshihiro Nanki, Hiroshi Ide, Satoshi Jodo, Kou Katayama, Hidekazu Matsushima, Yusuke Miwa, Koichi Morita, Hiroshi Nakashima, Hiroyuki Nakamura, Masamitsu Natsumeda, Yoshiko Sato, Seitaro Semba, Mutsuto Tateishi, Nobuyuki Miyasaka, Masayoshi Harigai: Tacrolimus-induced pulmonary injury in rheumatoid arthritis patients. Pulm Pharmacol Ther. 2011.08; 24 (4): 401-406. ( PubMed , DOI )

Ryoko Sakai, Yukiko Komano, Michi Tanaka, Toshihiro Nanki, Ryuji Koike, Atsuo Nakajima, Tatsuya Atsumi, Shinsuke Yasuda, Yoshiya Tanaka, Kazuyoshi Saito, Shigeto Tohma, Takao Fujii, Atsushi Ihata, Naoto Tamura, Atsushi Kawakami, Takahiko Sugihara, Satoshi Ito, Nobuyuki Miyasaka, Masayoshi Harigai: The REAL database reveals no significant risk of serious infection during treatment with a methotrexate dose of more than 8 mg/week in patients with rheumatoid arthritis. Mod Rheumatol. 2011.08; 21 (4): 444-448. ( PubMed , DOI )

Yukiko Komano, Michi Tanaka, Toshihiro Nanki, Ryuji Koike, Ryoko Sakai, Hideto Kameda, Atsuo Nakajima, Kazuyoshi Saito, Mitsuhiro Takeno, Tatsuya Atsumi, Shigeto Tohma, Satoshi Ito, Naoto Tamura, Takao Fujii, Tetsuji Sawada, Hiroaki Ida, Akira Hashiramoto, Takao Koike, Yoshiaki Ishigatsubo, Katsumi Eguchi, Yoshiya Tanaka, Tsutomu Takeuchi, Nobuyuki Miyasaka, Masayoshi Harigai, : Incidence and risk factors for serious infection in patients with rheumatoid arthritis treated with tumor necrosis factor inhibitors: a report from the Registry of Japanese Rheumatoid Arthritis Patients for Longterm Safety. J. Rheumatol.. 2011.07; 38 (7): 1258-1264. ( PubMed , DOI )

K. Otomo, O. Amengual, T. Atsumi, Y. Fujieda, M. Kato, T. Horita, S. Yasuda, W. Binder, T. Koike: Phosphatidylserine-dependent antiprothrombin antibodies (aPS/Pt) is a useful predictive marker of thrombosis in patients with autoimmune diseases JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2011.07; 9 419-420.

K. Oku, T. Atsumi, O. Amengual, Y. Fujieda, K. Otomo, M. Kato, S. Furukawa, H. Kitakawa, S. Yasuda, T. Horita, Y. Hori, T. Nishikawa, K. Nihei, M. Ieko, T. Koike: Platelet activation and paradoxical inhibition of ADP induced aggregation by antiphospholipid antibodies in vitro JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2011.07; 9 165.

Y. Fujieda, T. Atsumi, K. Otomo, M. Kato, K. Oku, O. Amegual, S. Yasuda, T. Horita, T. Koike: Predominant prevalence of stroke in Japanese patients with the antiphospholipid syndrome JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2011.07; 9 514-515.

Fujieda Yuichiro, Kataoka Hiroshi, Odani Toshio, Otomo Kotaro, Kato Masaru, Fukaya Shinji, Oku Kenji, Horita Tetsuya, Yasuda Shinsuke, Atsumi Tatsuya, Koike Takao: Clinical features of reversible posterior leukoencephalopathy syndrome in patients with systemic lupus erythematosus MODERN RHEUMATOLOGY. 2011.06; 21 (3): 276-281. ( DOI )

Bohgaki Miyuki, Matsumoto Masaki, Atsumi Tatsuya, Kondo Takeshi, Yasuda Shinsuke, Horita Tetsuya, Nakayama Keiichi I., Okumura Fumihiko, Hatakeyama Shigetsugu, Koike Takao: Plasma gelsolin facilitates interaction between beta(2) glycoprotein I and alpha(5)beta(1) integrin JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2011.01; 15 (1): 141-151. ( DOI )

Toko Hashimoto, Shinsuke Yasuda, Hideyuki Koide, Hiroshi Kataoka, Tetsuya Horita, Tatsuya Atsumi, Takao Koike: Aberrant splicing of the hRasGRP4 transcript and decreased levels of this signaling protein in the peripheral blood mononuclear cells in a subset of patients with rheumatoid arthritis ARTHRITIS RESEARCH & THERAPY. 2011; 13 (5): R154. ( PubMed , DOI )

Kayoko Kaneko, Toshihiro Nanki, Tadashi Hosoya, Fumitaka Mizoguchi, Nobuyuki Miyasaka: Etanercept-induced necrotizing crescentic glomerulonephritis in two patients with rheumatoid arthritis. Mod Rheumatol. 2010.12; 20 (6): 632-636. ( PubMed , DOI )

Kaneko Kayoko, Nanki Toshihiro, Hosoya Tadashi, Mizoguchi Fumitaka, Miyasaka Nobuyuki: 関節リウマチ患者2例におけるエタネルセプトで誘発された壊死性半月体形成性糸球体腎炎(Etanercept-induced necrotizing crescentic glomerulonephritis in two patients with rheumatoid arthritis) Modern Rheumatology. 2010.12; 20 (6): 632-636. ( ichushi )

Minori Tamai, Tsuyoshi Shimada, Nobuhiko Hiramatsu, Kunihiro Hayakawa, Maro Okamura, Yasuhiro Tagawa, Shuhei Takahashi, Shotaro Nakajima, Jian Yao, Masanori Kitamura: Selective deletion of adipocytes, but not preadipocytes, by TNF-alpha through C/EBP- and PPARgamma-mediated suppression of NF-kappaB. Lab. Invest.. 2010.09; 90 (9): 1385-1395. ( PubMed , DOI )

Suzuki Eriko, Amengual Olga, Atsumi Tatsuya, Oku Kenji, Hashimoto Toko, Kataoka Hiroshi, Horita Tetsuya, Yasuda Shinsuke, Ieko Masahiro, Fukushima Kazuaki, Koike Takao: Increased Expression of Phospholipid Scramblase 1 in Monocytes from Patients with Systemic Lupus Erythematosus JOURNAL OF RHEUMATOLOGY. 2010.08; 37 (8): 1639-1645. ( DOI )

Tetsuo Kubota, Ryuji Koike: Cryopyrin-associated periodic syndromes: background and therapeutics. Mod Rheumatol. 2010.06; 20 (3): 213-221. ( PubMed , DOI )

Matsuura E., Shen L., Matsunami Y., Quan N., Makarova M., Geske F. J., Boisen M., Yasuda S., Kobayashi K., Lopez L. R.: Pathophysiology of beta(2)-glycoprotein I in antiphospholipid syndrome LUPUS. 2010.04; 19 (4): 379-384. ( DOI )

Kunihiro Hayakawa, Shotaro Nakajima, Nobuhiko Hiramatsu, Maro Okamura, Tao Huang, Yukinori Saito, Yasuhiro Tagawa, Minori Tamai, Shuhei Takahashi, Jian Yao, Masanori Kitamura: ER stress depresses NF-kappaB activation in mesangial cells through preferential induction of C/EBP beta. J. Am. Soc. Nephrol.. 2010.01; 21 (1): 73-81. ( PubMed , DOI )

Kayoko Kaneko, Yoshinori Nonomura, Kaori Watanabe, Ryuji Koike, Tetsuo Kubota, Masayoshi Harigai, Yoshinori Inoue, Takehisa Iwai, Nobuyuki Miyasaka: Infected abdominal aortic aneurysm caused by nontyphoid Salmonella in an immunocompromised patient with rheumatoid arthritis. J. Infect. Chemother.. 2009.10; 15 (5): 312-315. ( PubMed , DOI )

Nakagawa Hisako, Yasuda Shinsuke, Matsuura Eiji, Kobayashi Kazuko, Ieko Masahiro, Kataoka Hiroshi, Horita Tetsuya, Atsumi Tatsuya, Koike Takao: Nicked beta 2-glycoprotein I binds angiostatin 4.5 (plasminogen kringle 1-5) and attenuates its antiangiogenic property BLOOD. 2009.09; 114 (12): 2553-2559. ( DOI )

Mai Mukai, Kunihiro Hayakawa, Maro Okamura, Yasuhiro Tagawa, Shotaro Nakajima, Yukinori Saito, Shuhei Takahashi, Jian Yao, Daisuke Nishimura, Masahito Sugi, Masaji Matsunaga, Masanori Kitamura: Preferential blockade of dioxin-induced activation of the aryl hydrocarbon receptor by Antrodia camphorata. Biol. Pharm. Bull.. 2009.09; 32 (9): 1510-1515. ( PubMed )

Horita T., Atsumi T., Yoshida N., Nakagawa H., Kataoka H., Yasuda S., Koike T.: STAT4 single nucleotide polymorphism, rs7574865 G/T, as a risk for antiphospholipid syndrome ANNALS OF THE RHEUMATIC DISEASES. 2009.08; 68 (8): 1366-1367. ( DOI )

Sakai Yoshie, Atsumi Tatsuya, Ieko Masahiro, Amengual Olga, Furukawa Shin, Furusaki Akira, Bohgaki Miyuki, Kataoka Hiroshi, Horita Tetsuya, Yasuda Shinsuke, Koike Takao: The Effects of Phosphatidylserine-Dependent Antiprothrombin Antibody on Thrombin Generation ARTHRITIS AND RHEUMATISM. 2009.08; 60 (8): 2457-2467. ( DOI )

Hiroaki Yamazaki, Nobuhiko Hiramatsu, Kunihiro Hayakawa, Yasuhiro Tagawa, Maro Okamura, Ryouji Ogata, Tao Huang, Shotaro Nakajima, Jian Yao, Adrienne W Paton, James C Paton, Masanori Kitamura: Activation of the Akt-NF-kappaB pathway by subtilase cytotoxin through the ATF6 branch of the unfolded protein response. J. Immunol.. 2009.07; 183 (2): 1480-1487. ( PubMed , DOI )

Oku K., Atsumi T., Bohgaki M., Amengual O., Kataoka H., Horita T., Yasuda S., Koike T.: Complement activation in patients with primary antiphospholipid syndrome ANNALS OF THE RHEUMATIC DISEASES. 2009.06; 68 (6): 1030-1035. ( DOI )

Bohgaki Toshiyuki, Atsumi Tatsuya, Bohgaki Miyuki, Furusaki Akira, Kondo Makoto, Sato-Matsumura Kazuko C., Abe Riichiro, Kataoka Hiroshi, Horita Tetsuya, Yasuda Shinsuke, Amasaki Yoshiharu, Nishio Mitsufumi, Sawada Ken-Ichi, Shimizu Hiroshi, Koike Takao: Immunological Reconstitution after Autologous Hematopoietic Stem Cell Transplantation in Patients with Systemic Sclerosis: Relationship Between Clinical Benefits and Intensity of Immunosuppression JOURNAL OF RHEUMATOLOGY. 2009.06; 36 (6): 1240-1248. ( DOI )

Yukiko Komano, Masayoshi Harigai, Ryuji Koike, Haruhito Sugiyama, Jun Ogawa, Kazuyoshi Saito, Naoya Sekiguchi, Masayuki Inoo, Ikuko Onishi, Hiroyuki Ohashi, Fujio Amamoto, Masayuki Miyata, Hideo Ohtsubo, Kazuko Hiramatsu, Masahiro Iwamoto, Seiji Minota, Naoki Matsuoka, Goichi Kageyama, Kazuyoshi Imaizumi, Hitoshi Tokuda, Yasumi Okochi, Koichiro Kudo, Yoshiya Tanaka, Tsutomu Takeuchi, Nobuyuki Miyasaka: Pneumocystis jiroveci pneumonia in patients with rheumatoid arthritis treated with infliximab: a retrospective review and case-control study of 21 patients. Arthritis Rheum.. 2009.03; 61 (3): 305-312. ( PubMed , DOI )

Yamada Hideto, Atsumi Tatsuya, Kobashi Gen, Ota Chikako, Kato Emi H., Tsuruga Noriko, Ohta Kaori, Yasuda Shinsuke, Koike Takao, Minakami Hisanori: Antiphospholipid antibodies increase the risk of pregnancy-induced hypertension and adverse pregnancy outcomes JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2009.01; 79 (2): 188-195. ( DOI )

Koike R, Harigai M, Atsumi T, Amano K, Kawai S, Saito S, Yamamura M, Matsubara T, Miyasaka N.: Japan College of Rheumatology 2009 guidelines for the use of tocilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, in rheumatoid arthritis. Mod Rheumatol. 2009; 19 351-357.

Komano Y, Harigai M, Koike R, Sugiyama H, Ogawa J Saito K, Sekiguchi N, Inoo M, Onishi I, Ohashi H, Amamoto F, Miyata M, Ohtsubo H, Hiramatsu K, Iwamoto M, Minota S, Matsuoka N, Kageyama G, Imaizumi K, Tokuda H, Okochi Y, Kudo K, Tanaka Y, Takeuchi T, Miyasaka N.: Pneumocystis pneumonia in patients with rheumatoid arthritis treated with infliximab: a retrospective review and case-control study of 21 patients. Arthritis Care Res. 2009; 61 (3): 305-312.

Fukaya S., Yasuda S., Hashimoto T., Oku K., Kataoka H., Horita T., Atsumi T., Koike T.: Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases: analysis of 30 cases RHEUMATOLOGY. 2008.11; 47 (11): 1686-1691. ( DOI )

Mai Mukai, Ayumi Kasai, Nobuhiko Hiramatsu, Kunihiro Hayakawa, Maro Okamura, Yasuhiro Tagawa, Jian Yao, Tomoyuki Nakamura, Masanori Kitamura: Blockade of the aryl hydrocarbon receptor pathway triggered by dioxin, polycyclic aromatic hydrocarbons and cigarette smoke by Phellinus linteus. Biol. Pharm. Bull.. 2008.10; 31 (10): 1888-1893. ( PubMed )

Tetsuya Horita, Nobuya Yoshida, Hisako Nakagawa, Hiroshi Kataoka, Shinsuke Yasuda, Tatsuya Atsumi, Takao Koike: STAT4 polymorphisms are associated with not only systemic lupus erythematosus, but also antiphospholipid syndrome ARTHRITIS AND RHEUMATISM. 2008.09; 58 (9): S175-S176.

Kenji Oku, Tatsuya Atsumi, Olga Amengual, Eriko Miyamoto, Kotaro Otomo, Masaru Kato, Hiroshi Kataoka, Tetsuya Horita, Shinsuke Yasuda, Takao Koike: The phosphatidylserine-dependent monoclonal antiprothrombin antibody with lupus anticoagulant activity induces tissue factor and adhesion molecules expression on endothelial cells: Possible implication of p38 mitogen-activate protein kinase (MAPK) pathway ARTHRITIS AND RHEUMATISM. 2008.09; 58 (9): S404-S405.

Shinsuke Yasuda, Richard L. Stevens, Tomoko Terada, Toko Hashimoto, Hiroshi Kataoka, Tetsuya Horita, Tatsuya Atsumi, Takao Koike: Alternative splicing of RasGRP1 in lupus patients: Frequency, clinical features and cytokine production ARTHRITIS AND RHEUMATISM. 2008.09; 58 (9): S817-S818.

Yasuhiro Tagawa, Nobuhiko Hiramatsu, Ayumi Kasai, Kunihiro Hayakawa, Maro Okamura, Jian Yao, Masanori Kitamura: Induction of apoptosis by cigarette smoke via ROS-dependent endoplasmic reticulum stress and CCAAT/enhancer-binding protein-homologous protein (CHOP). Free Radic. Biol. Med.. 2008.07; 45 (1): 50-59. ( PubMed , DOI )

Kataoka Hiroshi, Atsumi Tatsuya, Hashimoto Toko, Horita Tetsuya, Yasuda Shinsuke, Koike Takao: Polymyalgia rheumatica as the manifestation of unclassified aortitis MODERN RHEUMATOLOGY. 2008.02; 18 (1): 105-108. ( DOI )

Y. Kon, T. Atsumi, H. Hagiwara, A. Furusaki, H. Kataoka, T. Horita, S. Yasuda, O. Amengual, K. Takao: Thrombotic microangiopathy in patients with phosphatidylserine dependent antiprothrombin antibodies and antiphospholipid syndrome CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2008.01; 26 (1): 129-132. ( PubMed )

Kon Y., Atsumi T., Hagiwara H., Furusaki A., Kataoka H., Horita T., Yasuda S., Amengual O., Takao K.: Thrombotic microangiopathy in patients with phosphatidylserine dependent antiprothrombin antibodies and antiphospholipid syndrome CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2008; 26 (1): 129-132.

Satoshi Endo, Nobuhiko Hiramatsu, Kunihiro Hayakawa, Maro Okamura, Ayumi Kasai, Yasuhiro Tagawa, Norifumi Sawada, Jian Yao, Masanori Kitamura: Geranylgeranylacetone, an inducer of the 70-kDa heat shock protein (HSP70), elicits unfolded protein response and coordinates cellular fate independently of HSP70. Mol. Pharmacol.. 2007.11; 72 (5): 1337-1348. ( PubMed , DOI )

Shinsuke Yasuda, Richard L. Stevens, Tomoko Terada, Masumi Takeda, Toko Hashimoto, Jun Fukae, Tetsuya Horita, Hiroshi Kataoka, Tatsuya Atsumi, Takao Koike: Defective expression of ras guanyl nucleotide-releasing protein 1 in a subset of patients with systemic lupus erythematosus JOURNAL OF IMMUNOLOGY. 2007.10; 179 (7): 4890-4900. ( PubMed )

Yasuda Shinsuke, Stevens Richard L., Terada Tomoko, Takeda Masumi, Hashimoto Toko, Fukae Jun, Horita Tetsuya, Kataoka Hiroshi, Atsumi Tatsuya, Koike Takao: Defective expression of ras guanyl nucleotide-releasing protein 1 in a subset of patients with systemic lupus erythematosus JOURNAL OF IMMUNOLOGY. 2007.10; 179 (7): 4890-4900.

Amengual Olga, Atsumi Tatsuya, Komano Yukiko, Kataoka Hiroshi, Horita Tetsuya, Yasuda Shinsuke, Koike Takao: A polymorphism in human platelet antigen 6b and risk of thrombocytopenia in patients with systemic lupus erythematosus ARTHRITIS AND RHEUMATISM. 2007.08; 56 (8): 2803-2805. ( DOI )

T. Bohgaki, T. Atsumi, M. Bohgaki, A. Furusaki, M. Kondo, M. Nishio, H. Kataoka, T. Horita, S. Yasuda, Y. Amasaki, T. Koike: Clinical effect of autologous hematopoietic stem cell transplantation against interstitial pneumonia in patients with systemic sclerosis ANNALS OF THE RHEUMATIC DISEASES. 2007.07; 66 202.

T. Hashimoto, S. Yasuda, H. Kataoka, T. Horita, T. Atsumi, R. L. Stevens, T. Koike: Altered expression of RASGRP4 in a subset of patients with rheumatoid arthritis ANNALS OF THE RHEUMATIC DISEASES. 2007.07; 66 289.

H. Kataoka, Y. Kawase, T. Horita, S. Yasuda, T. Atsumi, T. Koike: Impaired homeostasis of regulatory T cells in patients with systemic lupus erythematosus ANNALS OF THE RHEUMATIC DISEASES. 2007.07; 66 309.

T. Horita, H. Nakagawa, Y. Sakai, H. Kataoka, S. Yasuda, T. Atsumi, T. Koike: CD45 exon 6 A138G polymorphism is associated with antiphospholipid syndrome CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2007.03; 25 (2): 137.

K. Oku, T. Atsumi, O. Amengual, H. Kataoka, T. Horita, S. Yasuda, T. Koike: Phosphatidylserine dependent antiprothrombin antibody induces p38 mitogen-activated protein kinase (MAPK) phosphorylation leading to tissue factor expression CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2007.03; 25 (2): 160.

T. Horita, K. Ichikawa, H. Kataoka, S. Yasuda, T. Atsumi, T. Koike: Human monoclonal antibodies against the complex of phosphatidylserine and prothrombin from patients with the antiphospholipid antibodies LUPUS. 2007; 16 (7): 509-516. ( PubMed , DOI )

Horita T., Ichikawa K., Kataoka H., Yasuda S., Atsumi T., Koike T.: Human monoclonal antibodies against the complex of phosphatidylserine and prothrombin from patients with the antiphospholipid antibodies LUPUS. 2007; 16 (7): 509-516. ( DOI )

Koike R, Kubota T, Hara Y, Ito S, Suzuki K, Yanagisawa K, Uchibori K, Miyasaka N.: A case of Muckle-Wells syndrome caused by a novel H312P mutation in NALP3(cryopyrin). Mod Rheumatol. 2007; 17 496-499.

Harigai M, Koike R, Miyasaka N.: Pneumocystis pneumonia associated with infliximab in Japan. N Engl J Med. 2007; 357 1874-1876.

Koike R, Takeuchi T, Eguchi K, Miyasaka N.: Update on the Japanese guidelines for the use of infliximab and etanercept in rheumatoid arthritis. Mod Rheumatol. 2007; 17 451-458.

Furukawa S., Yasuda S., Amengual O., Horita T., Atsumi T., Koike T.: Protective effect of pravastatin on vascular endothelium in patients with systemic sclerosis: a pilot study ANNALS OF THE RHEUMATIC DISEASES. 2006.08; 65 (8): 1118-1120. ( DOI )

A. Kusunoki, S. Yasuda, T. Horita, T. Atsumi, T. Koike: R131 allele of Fcg receptor IIA polymorphism is a risk factor in patients with systemic lupus erythematosus ANNALS OF THE RHEUMATIC DISEASES. 2006.07; 65 203.

Kasahara H, Matsuura E, Kaihara K, Yamamoto D, Kobayashi K, Inagaki J, Ichikawa K, Tsutsumi A, Yasuda S, Atsumi T, Yasuda T, Koike T: Antigenic structures recognized by anti-beta 2-glycoprotein I auto-antibodies INTERNATIONAL IMMUNOLOGY. 2005.12; 17 (12): 1533-1542. ( DOI )

Asako Emori, Eisuke Matsushima, Okihiko Aihara, Katsuya Ohta, Ryuji Koike, Nobuyuki Miyasaka, Motoichiro Kato: Cognitive dysfunction in systemic lupus erythematosus. Psychiatry Clin. Neurosci.. 2005.10; 59 (5): 584-589. ( PubMed , DOI )

A Tatsuya, O Amengual, Y Sakai, T Horita, S Yasuda, T Koike: Induction of tissue factor by monoclonal phosphatidylserine dependent antiprothrombin antibody. ARTHRITIS AND RHEUMATISM. 2005.09; 52 (9): S599-S600.

A Olga, A Tatsuya, S Yoshie, T Horita, S Yasuda, T Koike: Induction of lipid scramblase mRNA by antiphosphospholip antibodies: A new possible pathogenic mechanism of thrombosis in patients with antiphosphopholipid syndrome. ARTHRITIS AND RHEUMATISM. 2005.09; 52 (9): S252-S253.

Y Sakai, T Atsumi, O Amengual, S Yasuda, M Ieko, T Koike: Effects of phosphatidylserine dependent antiprothrombin antibody on thrombin generation in vitro. ARTHRITIS AND RHEUMATISM. 2005.09; 52 (9): S599.

K Oku, T Atsumi, M Bohgaki, Y Sakai, T Horita, S Yasuda, T Koike: High prevalence of hypocomplementemia in patients with primary antiphospholipid syndrome. ARTHRITIS AND RHEUMATISM. 2005.09; 52 (9): S596.

Fukae J, Amasaki Y, Yamashita Y, Bohgaki T, Yasuda S, Jodo S, Atsumi T, Koike T: Butyrate suppresses tumor necrosis factor alpha production by regulating specific messenger RNA degradation mediated through a cis-acting AU-rich element ARTHRITIS AND RHEUMATISM. 2005.09; 52 (9): 2697-2707. ( DOI )

Atsumi T, Amengual O, Yasuda S, Matsuura E, Koike T: Research around beta 2-glycoprotein I: A major target for antiphospholipid antibodies AUTOIMMUNITY. 2005.08; 38 (5): 377-381. ( DOI )

Kenji Oda, Eisuke Matsushima, Yoshiro Okubo, Katsuya Ohta, Yuji Murata, Ryuji Koike, Nobuyuki Miyasaka, Motoichiro Kato: Abnormal regional cerebral blood flow in systemic lupus erythematosus patients with psychiatric symptoms. J Clin Psychiatry. 2005.07; 66 (7): 907-913. ( PubMed )

JP Abonia, DS Friend, WG Austen, FD Moore, MC Carroll, R Chan, J Afnan, A Humbles, C Gerard, P Knight, Y Kanaoka, S Yasuda, N Morokawa, KF Austen, RL Stevens, MF Gurish: Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle JOURNAL OF IMMUNOLOGY. 2005.06; 174 (11): 7285-7291. ( PubMed )

Abonia JP, Friend DS, Austen WG, Moore FD, Carroll MC, Chan R, Afnan J, Humbles A, Gerard C, Knight P, Kanaoka Y, Yasuda S, Morokawa N, Austen KF, Stevens RL, Gurish MF: Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle JOURNAL OF IMMUNOLOGY. 2005.06; 174 (11): 7285-7291.

Yasuda S, Morokawa N, Wong GW, Rossi A, Madhusudhan MS, Sali A, Askew YS, Adachi R, Silverman GA, Krilis SA, Stevens RL: Urokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase epsilon/PRSS22 BLOOD. 2005.05; 105 (10): 3893-3901. ( DOI )

Yasuda S, Atsumi T, Matsuura E, Kaihara K, Yamamoto D, Ichikawa K, Koike T: Significance of valine/leucine(247) polymorphism of beta(2)-glycoprotein I in antiphospholipid syndrome - Increased reactivity of anti-beta(2)-glycoprotein I autoantibodies to the valine(247) gamma(2)-glycoprotein I variant ARTHRITIS AND RHEUMATISM. 2005.01; 52 (1): 212-218. ( DOI )

Yasuda S, Bohgaki M, Atsumi T, Koike T: Pathogenesis of antiphospholipid antibodies: impairment of fibrinolysis and monocyte activation via the p38 mitogen-activated protein kinase pathway IMMUNOBIOLOGY. 2005; 210 (10): 775-780. ( DOI )

Bohgaki M, Atsumi T, Yamashita Y, Yasuda S, Sakai Y, Furusaki A, Bohgaki T, Amengual O, Amasaki Y, Koike T: The p38 mitogen-activated protein kinase (MAPK) pathway mediates induction of the tissue factor gene in monocytes stimulated with human monoclonal anti-beta(2)Glycoprotein I antibodies INTERNATIONAL IMMUNOLOGY. 2004.11; 16 (11): 1633-1641. ( DOI )

S Furukawa, S Yasuda, Y Sakai, M Kondo, Y Kon, O Amengual, Y Amasaki, T Atsumi, T Koike: Protective effect of pravastatin on vascular endothelium in patients with systemic sclerosis: A pilot study ARTHRITIS AND RHEUMATISM. 2004.09; 50 (9): S693.

O Amengual, T Atsumi, S Yasuda, Y Amasaki, T Koike: Diagnostic value of matrix metalloproteinase 3 (MMP-3) in serum of patients with arthralgias ARTHRITIS AND RHEUMATISM. 2004.09; 50 (9): S161-S162.

T Bohgaki, Y Amasaki, N Nishimura, Y Yamashita, M Nishio, K Sawada, S Yasuda, T Atsumi, T Koike: Specific upregulation of tumor necrosis factor alpha (TNFa) converting enzyme(TACE) expression in patients with systemic sclerosis ARTHRITIS AND RHEUMATISM. 2004.09; 50 (9): S639.

T Atsumi, M Ieko, Y Sakai, Y Kon, S Furukawa, O Amengual, S Yasuda, Y Amasaki, T Koike: Phosphatidylserine dependent antiprothrombin antibodies provide one of the best diagnostic values for the laboratory evaluation in patients with antiphospholipid syndrome. ARTHRITIS AND RHEUMATISM. 2004.09; 50 (9): S68-S69.

S Yasuda, T Atsumi, M Ieko, E Matsuura, Y Amasaki, T Koike: Nicked beta2-glycoprotein I binds to plasminogen and plays a role in extrinsic fibrinolysis via negative feedback mechanism ARTHRITIS AND RHEUMATISM. 2004.09; 50 (9): S640.

Yasuda S, Atsumi T, Ieko M, Matsuura E, Kobayashi K, Inagaki J, Kato H, Tanaka H, Yamakado M, Akino M, Saitou H, Amasaki Y, Jodo S, Amengual O, Koike T: Nicked beta(2)-glycoprotein I: a marker of cerebral infarct and a novel role in the negative feedback pathway of extrinsic fibrinolysis BLOOD. 2004.05; 103 (10): 3766-3772. ( DOI )

Shinsuke Yasuda, Nobutaka Ogura, Tetsuya Horita, Izumi Yasuda, Takaya Hioka, Nobuo Kondo, Atsushi Fujisaku: Abacterial prostatitis and primary biliary cirrhosis with Sjögren's syndrome Modern Rheumatology. 2004.03; 14 (1): 70-72. ( PubMed , DOI )

S Yasuda, GW Wong, A Rossi, MS Madhusudhan, N Morokawa, A Sali, SA Krilis, RL Stevens: Urokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase epsilon/PRSS22 FASEB JOURNAL. 2004.03; 18 (5): A793.

Wong GW, Yasuda S, Morokawa N, Li LX, Stevens RL: Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns JOURNAL OF BIOLOGICAL CHEMISTRY. 2004.01; 279 (4): 2438-2452. ( DOI )

Y Sakai, T Atsumi, Y Kon, M Bohgaki, S Yasuda, O Amengual, Y Amasaki, T Koike: Clinical and immunological manifestations of Japanese patients with antiphospholipid syndrome (APS): A cohort of 82 patients THROMBOSIS RESEARCH. 2004; 114 (5-6): 663-664.

Y Kon, T Atsumi, M Kondo, Y Sakai, S Yasuda, Y Amasaki, T Koike: Thrombotic thrombocytopenic purpura in two patients with antiphospholipid syndrome THROMBOSIS RESEARCH. 2004; 114 (5-6): 651.

O Amengual, T Atsumi, K Yujiro, Y Sakai, M Bohgaki, S Furukawa, S Yasuda, Y Amasaki, M Ieko, T Koike: The value of IGM phosphatidylserine dependent antiprothrombin antibody determination for the diagnosis of antiphospholipid syndrome THROMBOSIS RESEARCH. 2004; 114 (5-6): 671-672.

T Atsumi, O Amengual, S Yasuda, T Koike: Antiprothrombin antibodies-are they worth assaying? THROMBOSIS RESEARCH. 2004; 114 (5-6): 533-538. ( DOI )

Atsumi T, Amengual O, Yasuda S, Koike T: Antiprothrombin antibodies-are they worth assaying? THROMBOSIS RESEARCH. 2004; 114 (5-6): 533-538. ( DOI )

Yasuda S, Atsumi T, Ieko M, Koike T: beta 2-glycoprotein I, anti-beta 2-glycoprotein 1, and fibrinolysis THROMBOSIS RESEARCH. 2004; 114 (5-6): 461-465. ( DOI )

Hasegawa H, Fukushima T, Lee JA, Tsukamoto K, Moriya K, Ono Y, Imai K.: Determination of serum D-lactic and L-lactic acids in normal subjects and diabetic patients by column-switching HPLC with pre-column fluorescence derivatization. Analytical and Bioanalytical Chemistry. 2003.11; 377 886-891.

Hashimoto K, Fukushima T, Shimizu E, Komatsu N, Watanabe H, Shinoda N, Nakazato M, Kumakiri C, Okada S, Hasegawa H, Imai K, Iyo M.: Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia. Archives of General Psychiatry. 2003.06; 60 572-576.

S Yasuda, GW Wong, SA Krilis, RL Stevens: Activation of urokinase-type plasminogen activator (uPA) by human tryptase epsilon/PRSS22 FASEB JOURNAL. 2003.04; 17 (7): C12.

GW Wong, Y Yang, S Yasuda, RL Stevens, LX Li: Mouse mast cells (MCs) express the tryptic-like serine protease neuropsin/KLK8/Prss19 FASEB JOURNAL. 2003.04; 17 (7): C11.

H Hagiyama, R Koike, K Nagasaka, Y Nonomura, J Nishio, T Nanki, H Kohsaka, T Kubota, N Miyasaka: Two cases of acute respiratory distress syndrome resulting from adult-onset Still's disease. Mod Rheumatol. 2003.03; 13 (1): 76-80. ( PubMed , DOI )

Wong GW, Yang Y, Yasuda S, Li LX, Stevens RL: Mouse mast cells express the tryptic protease neuropsin/Prss19 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003.03; 303 (1): 320-325. ( DOI )

Wong GW, Foster PS, Yasuda S, Qi JC, Mahalingam S, Mellor EA, Katsoulotos G, Li LX, Boyce JA, Krilis SA, Stevens RL: Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma JOURNAL OF BIOLOGICAL CHEMISTRY. 2002.11; 277 (44): 41906-41915. ( DOI )

S Yasuda, A Tsutsumi, T Atsumi, ML Bertolaccini, K Ichikawa, MA Khamashta, GRV Hughes, T Koike: Gene polymorphisms of tissue plasminogen activator and plasminogen activator inhibitor-1 in patients with antiphospholipid antibodies JOURNAL OF RHEUMATOLOGY. 2002.06; 29 (6): 1192-1197. ( PubMed )

Yasuda S, Tsutsumi A, Atsumi T, Bertolaccini ML, Ichikawa K, Khamashta MA, Hughes GRV, Koike T: Gene polymorphisms of tissue plasminogen activator and plasminogen activator inhibitor-1 in patients with antiphospholipid antibodies JOURNAL OF RHEUMATOLOGY. 2002.06; 29 (6): 1192-1197.

T Horita, A Tsutsumi, T Takeda, S Yasuda, R Takeuchi, Y Amasaki, K Ichikawa, T Atsumi: Significance of magnetic resonance imaging in the diagnosis of nodular regenerative hyperplasia of the liver complicated with systemic lupus erythematosus: a case report and review of the literature LUPUS. 2002; 11 (3): 193-196. ( PubMed , DOI )

Horita T, Tsutsumi A, Takeda T, Yasuda S, Takeuchi R, Amasaki Y, Ichikawa K, Atsumi T: Significance of magnetic resonance imaging in the diagnosis of nodular regenerative hyperplasia of the liver complicated with systemic lupus erythematosus: a case report and review of the literature LUPUS. 2002; 11 (3): 193-196.

Wong GW, Yasuda S, Madhusudhan MS, Li LX, Yang Y, Krilis SA, Sali A, Stevens RL: Human tryptase epsilon (PRSS22), a new member of the chromosome 16p13.3 family of human serine proteases expressed in airway epithelial cells JOURNAL OF BIOLOGICAL CHEMISTRY. 2001.12; 276 (52): 49169-49182. ( DOI )

K Shimabukuro, S Ichinose, R Koike, T Kubota, M Yamaguchi, M Miyasaka, T Aso: Hepatocyte growth factor/scatter factor is implicated in the mode of stromal invasion of uterine squamous cervical cancer. Gynecol. Oncol.. 2001.11; 83 (2): 205-215. ( PubMed , DOI )

R Koike, T Iizuka, T Watanabe, N Miyasaka: The GOR gene product cannot cross-react with hepatitis C virus in humans. Clin. Exp. Immunol.. 2001.06; 124 (3): 429-434. ( PubMed )

Y Nonomura, R Koike, J Nishio, R Tsubata, H Kohsaka, T Kubota, N Miyasaka: Overlap syndrome with cerebral hemorrhage caused by prostaglandin E1 infusion. Intern. Med.. 2001.03; 40 (3): 265-266. ( PubMed )

S Yasuda, A Tsutsumi, H Chiba, H Yanai, Y Miyoshi, R Takeuchi, T Horita, T Atsumi, K Ichikawa, E Matsuura, T Koike: beta(2)-glycoprotein I deficiency: prevalence, genetic background and effects on plasma lipoprotein metabolism and hemostasis ATHEROSCLEROSIS. 2000.10; 152 (2): 337-346. ( PubMed , DOI )

Yasuda S, Tsutsumi A, Chiba H, Yanai H, Miyoshi Y, Takeuchi R, Horita T, Atsumi T, Ichikawa K, Matsuura E, Koike T: beta(2)-glycoprotein I deficiency: prevalence, genetic background and effects on plasma lipoprotein metabolism and hemostasis ATHEROSCLEROSIS. 2000.10; 152 (2): 337-346.

S Yasuda, T Atsumi, K Ichikawa, E Matsuura, K Kaihara, T Yasuda, Y Amasaki, T Koike: Valine/leucine(247) polymorphism of beta 2-glycoprotein 1 affects the reactivity of anti-beta 2-glycoprotein 1 antibodies. ARTHRITIS AND RHEUMATISM. 2000.09; 43 (9): S404.

R Takeuchi, T Atsumi, M Ieko, H Takeya, S Yasuda, K Ichikawa, A Tsutsumi, K Suzuki, T Koike: Coagulation and fibrinolytic activities in 2 siblings with beta(2)-glycoprotein I deficiency BLOOD. 2000.08; 96 (4): 1594-1595. ( PubMed )

Takeuchi R, Atsumi T, Ieko M, Takeya H, Yasuda S, Ichikawa K, Tsutsumi A, Suzuki K, Koike T: Coagulation and fibrinolytic activities in 2 siblings with beta(2)-glycoprotein I deficiency BLOOD. 2000.08; 96 (4): 1594-1595.

T Nishimura, R Koike, M Miyasaka: Mammary glands of Aly mice: developmental changes and lactation-related expression of specific proteins, alpha-casein, GLyCAM-1 and MAdCAM-1. Am. J. Reprod. Immunol.. 2000.06; 43 (6): 351-358. ( PubMed )

T Iizuka, T Tanaka, M Suematsu, S Miura, T Watanabe, R Koike, Y Ishimura, H Ishii, N Miyasaka, M Miyasaka: Stage-specific expression of mucosal addressin cell adhesion molecule-1 during embryogenesis in rats. J. Immunol.. 2000.03; 164 (5): 2463-2471. ( PubMed )

T Nanki, R Koike, N Miyasaka: Subacute severe steatohepatitis during prednisolone therapy for systemic lupus erythematosis. Am. J. Gastroenterol.. 1999.11; 94 (11): 3379. ( PubMed , DOI )

H Satoh, T Iizuka, R Koike, N Miyasaka, K Kitada, T Kuramoto, T Serikawa, T Watanabe: Assignment of the Madcam1 gene to rat chromosome 7q11.2-->q12 by fluorescence in situ hybridization, somatic cell hybrids and linkage analysis. Cytogenet. Cell Genet.. 1999.10; 86 (3-4): 223-224. ( PubMed , DOI )

A Tsutsumi, K Sasaki, R Takeuchi, T Horita, S Yasuda, Y Miyoshi, T Atsumi, K Ichikawa, T Koike: Mannose binding lectin polymorphism in patients with collagen diseases. ARTHRITIS AND RHEUMATISM. 1999.09; 42 (9): S312.

S Yasuda, A Tsutsumi, T Atsumi, ML Bertolaccini, K Ichikawa, MA Khamashta, GRV Hughes, T Koike: Gene polymorphisms of tissue plasminogen activator and plasminogen activator inhibitor-1 in patients with antiphospholipid syndrome. ARTHRITIS AND RHEUMATISM. 1999.09; 42 (9): S371.

T Atsumi, M Ieko, ML Bertolaccini, R Takeuchi, T Horita, S Yasuda, Y Miyoshi, K Ichikawa, A Tsutsumi, T Koike: Anti phosphatidylserine-prothrombin antibody as a specific marker for clinical features of antiphospholipid syndrome in systemic autoimmune diseases. ARTHRITIS AND RHEUMATISM. 1999.09; 42 (9): S364.

S Yasuda, A Tsutsumi, T Nakabayashi, T Horita, K Ichikawa, M Ieko, T Koike: Haemophagocytic syndrome in a patient with dermatomyositis BRITISH JOURNAL OF RHEUMATOLOGY. 1998.12; 37 (12): 1357-1358. ( PubMed )

Yasuda S, Tsutsumi A, Nakabayashi T, Horita T, Ichikawa K, Ieko M, Koike T: Haemophagocytic syndrome in a patient with dermatomyositis BRITISH JOURNAL OF RHEUMATOLOGY. 1998.12; 37 (12): 1357-1358.

T Atsumi, M Ieko, R Takeuchi, T Horita, S Yasuda, H Kasahara, Y Miyoshi, K Ichikawa, A Tsutsumi, T Koike: Clinical significance of anti prothrombin-phosphatidylserine antibodies and their association with lupus anticoagulant in patients with autoimmune diseases. ARTHRITIS AND RHEUMATISM. 1998.09; 41 (9): S169.

T Nanki, R Koike, N Mizushima, H Kohsaka, T Kubota, N Miyasaka: Severe anemia due to hemorrhagic gastritis associated with Sjögren's syndrome. Clin. Exp. Rheumatol.. 1998.02; 16 (1): 105. ( PubMed )

T Iizuka, R Koike, N Miyasaka, M Miyasaka, T Watanabe: Cloning and characterization of the rat MAdCAM-1 cDNA and gene. Biochim. Biophys. Acta. 1998.02; 1395 (3): 266-270. ( PubMed )

R Koike, T Watanabe, H Satoh, C S Hee, K Kitada, T Kuramoto, T Serikawa, S Miyawaki, M Miyasaka: Analysis of expression of lymphocyte homing-related adhesion molecules in ALY mice deficient in lymph nodes and Peyer's patches. Cell. Immunol.. 1997.08; 180 (1): 62-69. ( PubMed , DOI )

N Mizushima, R Koike, H Kohsaka, Y Kushi, S Handa, H Yagita, N Miyasaka: Ceramide induces apoptosis via CPP32 activation. FEBS Lett.. 1996.10; 395 (2-3): 267-271. ( PubMed )

R Koike, T Nishimura, R Yasumizu, H Tanaka, Y Hataba, Y Hataba, T Watanabe, S Miyawaki, M Miyasaka: The splenic marginal zone is absent in alymphoplastic aly mutant mice. Eur. J. Immunol.. 1996.03; 26 (3): 669-675. ( PubMed , DOI )

H Komachi, K Tsuchiya, M Ikeda, R Koike, T Matsunaga, K Ikeda: Radiation myelopathy: a clinicopathological study with special reference to correlation between MRI findings and neuropathology. J. Neurol. Sci.. 1995.10; 132 (2): 228-232. ( PubMed )

R Koike, I Miki, M Otoshi, T Totsuka, H Inoue, H Kase, I Saito, N Miyasaka: Gold sodium thiomalate down-regulates intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 expression on vascular endothelial cells. Mol. Pharmacol.. 1994.10; 46 (4): 599-604. ( PubMed )

M Nanno, S Matsumoto, R Koike, M Miyasaka, M Kawaguchi, T Masuda, S Miyawaki, Z Cai, T Shimamura, Y Fujiura: Development of intestinal intraepithelial T lymphocytes is independent of Peyer's patches and lymph nodes in aly mutant mice. J. Immunol.. 1994.09; 153 (5): 2014-2020. ( PubMed )

T Kuramoto, T Mashimo, R Koike, S Miyawaki, J Yamada, M Miyasaka, T Serikawa: The alymphoplasia (aly) mutation co-segregates with the intercellular adhesion molecule-2 (lcam-2) on mouse chromosome 11. Int. Immunol.. 1994.07; 6 (7): 991-994. ( PubMed )

H Yoshinaga, R Koike, T Maruyama, H Iizuka, H Matsuoka, T Kubota, N Miyasaka: Still's disease relapse with severe pneumonitis after prolonged remission. Intern. Med.. 1993.12; 32 (12): 902-905. ( PubMed )

R Koike, M Yamada, T Matsunaga, S Yoshida, H Tsukagoshi: Polyarteritis nodosa (PN) complicated with unilateral exophthalmos. Intern. Med.. 1993.03; 32 (3): 232-236. ( PubMed )

N Miyasaka, H Inoue, T Totsuka, R Koike, K Kino, H Tsunoo: An immunomodulatory protein, Ling Zhi-8, facilitates cellular interaction through modulation of adhesion molecules. Biochem. Biophys. Res. Commun.. 1992.07; 186 (1): 385-390. ( PubMed )

庭野智子, 細矢匡: A20 haploinsufficiency in adulthood. 月刊リウマチ科. 2023.07; 70 (1): 119-122. ( ichushi )

川田大介, 細矢匡, 河本亜美, 梅澤夏佳, 長谷川久紀, 木村直樹, 岩井秀之, 岡本隆一, 保田晋助: A case of MEFV gene-related enterocolitis with novel missense mutation 日本免疫不全・自己炎症学会雑誌(Web). 2022; 1 (2): 77. ( ichushi )

Natsuka Umezawa: Novel Therapeutic targets for inflammatory myopathies Rheumatology. 2020.04; 63 (4): 433-437.

CD4+ and CD8+ CD28null T cells are cytotoxic to autologous muscle cells in patients with polymyositis RHEUMATOLOGY. 2017.07; 58 (1): 109-116.

久田 諒, 加藤 将, 菅原 恵理, 中村 浩之, 大村 一将, 中川 久子, 藤枝 雄一郎, 奥 健志, 坊垣 暁之, アメングアル・オルガ, 堀田 哲也, 保田 晋助, 渥美 達也: 抗リン脂質抗体症候群における末梢血リンパ球サブセットおよび一塩基多型(SNP)の解析 日本血栓止血学会誌. 2017.04; 28 (2): 229. ( ichushi )

Naoki Kimura: Safety and effectiveness of partial blood flow restriction training in polymyositis and dermatomyositis Rheumatology. 2015.09; 54 (3): 323-328.

A novel therapeutic concept for arthritis: Cell cycle regulation therapy combined with cytokine blockade 2015.07; 33 (12): 140-146.

Yuichiro Fujieda, Haruki Shida, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, Shinsuke Yasuda, Tatsuya Atsumi: Clinical significance of antiphospholipid antibody measured by EliA anticardiolipin antibodies and anti-β2Glycoprotein i antibodies in antiphospholipid syndrome Japanese Journal of Clinical Immunology. 2015.01; 37 (5): 430-436. ( PubMed , DOI )

Naoki Kimura, Hitoshi Kohsaka: Animal model of polymyositis/dermatomyositis Rheumatology. 2013.04; 49 (4): 420-429.

NAKAGAWA Hisako, YASUDA Shinsuke, MATSUURA Eiji, KOBAYASHI Kazuko, IEKO Masahiro, KATAOKA Hiroshi, HORITA Tetsuya, ATSUMI Tatsuya, KOIKE Takao: Nicked β2-glycoprotein I binds angiostatin 4.5 and attenuates its anti-angiogenic property Japanese Journal of Thrombosis and Hemostasis. 2010.06; 21 (3): 314-318. ( DOI )

Possible roles of RasGRP1 in autoimmunity Clinical immunology & allergology. 2009.04; 51 (4): 356-362.

NAKAGAWA Yasuko, KATAOKA Hiroshi, YASUDA Shinsuke, FUKAE Jun, HORITA Tetsuya, ATSUMI Tatsuya, KASHIWAZAKI Haruhiko, KOIKE Takao, INOUE Nobuo: Impaired expression of Id3 mRNA in B cells of patients with Sjogren's syndrome 2007.06; 28 (1): 27-35.

OHIRA Hiroshi, TSUTSUMI Akito, YASUDA Shinsuke, HORITA Tetsuya, TAKEUCHI Rie, KASAHARA Hideki, MIYOSHI Yoshinori, ATSUMI Tatsuya, ICHIKAWA Kenji, KOIKE Takao: Severe neuro - Behcet with perforation of the intestine Nihon Naika Gakkai Zasshi. 2000.07; 89 (7): 1435-1437. ( DOI )

Zento Yamada, Sei Muraoka, Mai Kawazoe, Wataru Hirose, Hajime Kono, Shinsuke Yasuda, Takahiko Sugihara, Toshihiro Nanki: Long-term effects of abatacept on atherosclerosis and arthritis in older vs. younger patients with rheumatoid arthritis: 3-year results of a prospective, multicenter, observational study Arthritis Research & Therapy. 2024.04; 26 (1): ( DOI )

Hiroyuki Baba, Tadashi Hosoya, Ryosuke Ishida, Kenpei Tai, Saki Hatsuzawa, Yuma Kondo, Hiroyuki Kusuhara, Hiroyuki Kagechika, Shinsuke Yasuda: Anti-Inflammatory Effects of a Novel Nuclear Factor–κB Inhibitory Derivative Derived from Pyrazolo[3,4-d]Pyrimidine in Three Inflammation Models Journal of Pharmacology and Experimental Therapeutics. 2024.03; ( DOI )

小宮陽仁, 細矢匡: Psychiatric disorders and neuroinflammation: Neuropsychiatric symptoms associated with connective tissue disease and COVID-19 臨床精神医学. 2024; 53 (4):

Takahiro Mitsumura, Tsukasa Okamoto, Mizuho Tosaka, Takashi Yamana, Sho Shimada, Yuki Iijima, Rie Sakakibara, Sho Shibata, Takayuki Honda, Tsuyoshi Shirai, Masahiro Ishizuka, Junichi Aiboshi, Haruhiko Furusawa, Tomoya Tateishi, Meiyo Tamaoka, Hidenobu Shigemitsu, Hirokuni Arai, Yasuhiro Otomo, Shuji Tohda, Tatsuhiko Anzai, Kunihiko Takahashi, Shinsuke Yasuda, Yasunari Miyazaki: SARS-CoV-2 RNA copy number is a factor associated with the mortality of COVID-19 and improves the predictive performance of mortality in severe cases. Japanese Journal of Infectious Diseases. 2022.05; ( DOI )

川田大介, 細矢匡, 河本亜美, 梅澤夏佳, 長谷川久紀, 木村直樹, 岩井秀之, 岡本隆一, 保田晋助: A case of MEFV gene-related enterocolitis with novel missense mutation 日本免疫不全・自己炎症学会雑誌(Web). 2022; 1 (2):

KUDO Yuki, KATO Masaru, SHIBATA Yuhei, KONO Michihito, FUJIEDA Yuichiro, AMENGUAL Olga, OKU Kenji, YASUDA Shinsuke, ATSUMI Tatsuya: Establishment and transcriptome analysis of systemic sclerosis associated pulmonary arterial hypertension-specific endothelial cells 日本リウマチ学会総会・学術集会プログラム・抄録集. 2020; 64th (CD-ROM)

NINAGAWA Keita, KATO Masaru, KONO Michihito, FUJIEDA Yuichiro, OKU Kenji, AMENGUAL Olga, YASUDA Shinsuke, ATSUMI Tatsuya: The assessment of left heart disease phenotype in patients with systemic sclerosis associated pulmonary arterial hypertension 日本リウマチ学会総会・学術集会プログラム・抄録集. 2020; 64th (CD-ROM)

KARINO Kohei, KONO Michihito, KONO Michihiro, KURITA Takashi, ABE Nobuya, FUJIEDA Yuichiro, KATO Masaru, AMENGUAL Olga, OKU Kenji, YASUDA Shinsuke, ATSUMI Tatsuya: Risk factors for vasculitis-derived manifestations in patients with dermatomyositis 日本リウマチ学会総会・学術集会プログラム・抄録集. 2020; 64th (CD-ROM)

OGATA Yusuke, FUJIEDA Yuichiro, SATO Taiki, OHNISHI Naoki, KONO Michihito, KATO Masaru, OKU Kenji, AMENGUAL Olga, YASUDA Shinsuke, ATSUMI Tatsuya: Risk factors for developing systemic lupus erythematosus in patients with primary antiphospholipid syndrome 日本リウマチ学会総会・学術集会プログラム・抄録集. 2020; 64th (CD-ROM)

YOSHIMURA Masaru, FUJIEDA Yuichiro, KONO Michihito, KATO Masaru, OKU Kenji, AMENGUAL Olga, YASUDA Shinsuke, ATSUMI Tatsuya: The risk assessment of developing deep vein thrombosis in patients with rheumatoid arthritis 日本リウマチ学会総会・学術集会プログラム・抄録集. 2020; 64th (CD-ROM)

SATO Taiki, AMENGUAL Olga, FUJIEDA Yuichiro, OHNISHI Naoki, ABE Nobuya, KONO Michihito, KATO Masaru, OKU Kenji, YASUDA Shinsuke, ATSUMI Tatsuya: Long-term persistence of IgM antiphospholipid antibodies and thrombotic risk 日本リウマチ学会総会・学術集会プログラム・抄録集. 2020; 64th (CD-ROM)

ABE Nobuya, OKU Kenji, KUDO Yuki, KARINO Kohei, KONO Michihito, FUJIEDA Yuichiro, AMENGUAL Olga, KATO Masaru, KAMIMURA Daisuke, YASUDA Shinsuke, MURAKAMI Masaaki, ATSUMI Tatsuya: The effect of antiphospholipid antibody on cognitive function and microglial activation in mice 日本リウマチ学会総会・学術集会プログラム・抄録集. 2020; 64th (CD-ROM)

Sato T, Nakamura H, Fujieda Y, Ohnishi N, Abe N, Kono M, Kato M, Oku K, Bohgaki T, Amengual O, Yasuda S, Atsumi T: Factor Xa inhibitors for preventing recurrent thrombosis in patients with antiphospholipid syndrome: a longitudinal cohort study. Lupus. 2019.11; 28 (13): 1577-1582. ( PubMed , DOI )

Sugawara E, Kato M, Kudo Y, Lee W, Hisada R, Fujieda Y, Oku K, Bohgaki T, Amengual O, Yasuda S, Onodera T, Hatakeyama S, Atsumi T: Autophagy promotes citrullination of VIM (vimentin) and its interaction with major histocompatibility complex class II in synovial fibroblasts. Autophagy. 2019.09; 16 (5): 1-10. ( PubMed , DOI )

Ninagawa K, Kato M, Nakamura H, Abe N, Kono M, Fujieda Y, Oku K, Yasuda S, Ohira H, Tsujino I, Atsumi T: Reduced diffusing capacity for carbon monoxide predicts borderline pulmonary arterial pressure in patients with systemic sclerosis. Rheumatology international. 2019.07; ( PubMed , DOI )

Ohnishi N, Fujieda Y, Hisada R, Nakamura H, Kato M, Oku K, Bohgaki T, Amengual O, Yasuda S, Atsumi T: Efficacy of dual antiplatelet therapy for preventing recurrence of arterial thrombosis in patients with antiphospholipid syndrome. Rheumatology (Oxford, England). 2019.06; 58 (6): 969-974. ( PubMed , DOI )

Hisada R, Kato M, Ohnishi N, Sugawara E, Fujieda Y, Oku K, Bohgaki T, Amengual O, Yasuda S, Atsumi T: Antiphospholipid score is a novel risk factor for idiopathic osteonecrosis of the femoral head in patients with systemic lupus erythematosus. Rheumatology (Oxford, England). 2019.04; 58 (4): 645-649. ( PubMed , DOI )

Fujieda Y, Mader S, Jeganathan V, Arinuma Y, Shimizu Y, Kato M, Oku K, Minami A, Shimizu C, Yasuda S, Atsumi T: Clinical significance of anti-DNA/N-methyl-D-aspartate receptor 2 antibodies in de novo and post-steroid cases with neuropsychiatric systemic lupus erythematosus. International journal of rheumatic diseases. 2019.03; 22 (3): 443-448. ( PubMed , DOI )

Noguchi A, Yasuda S, Hisada R, Kato M, Oku K, Bohgaki T, Suzuki M, Matsumoto Y, Atsumi T: Anti-cyclic citrullinated peptide antibody titers decrease in rheumatoid arthritis patients treated with tocilizumab: A pilot study. Modern rheumatology. 2019.02; 1-6. ( PubMed , DOI )

ASO Kuniyuki, KONO Michihito, KONO Michihiro, NINAGAWA Keita, SATO Taiki, WATANABE Toshiyuki, SHIMIZU Yuka, FUJIEDA Yuichiro, KATO Masaru, OKU Kenji, BOHGAKI Toshiyuki, OLGA Amengual, YASUDA Shinsuke, ATSUMI Tatsuya: Predictors of neuropsychiatric flare in patients with systemic lupus erythematosus 日本リウマチ学会総会・学術集会プログラム・抄録集. 2019; 63rd

LEE Wen Shi, KATO Masaru, SUGAWARA Eri, KONO Michihiro, KUDO Yuki, KONO Michihito, FUJIEDA Yuichiro, BOHGAKI Toshiyuki, AMENGUAL Olga, OKU Kenji, YASUDA Shinsuke, ATSUMI Tatsuya: Autophagy Receptor Optineurin in Synovial Fibroblasts Plays a Protective Role against Joint Destructions in Rheumatoid Arthritis 日本免疫学会総会・学術集会記録(CD-ROM). 2019; 48

ABE Nobuya, FUJIEDA Yuichiro, KARINO Kohei, KONO Michihito, KATO Masaru, OKU Kenji, BOHGAKI Toshiyuki, AMENGUAL Olga, YASUDA Shinsuke, ATSUMI Tatsuya: Enhanced resting-state functional connectivity of pain processing regions associated with insufficient response to biologics in inflammatory arthritis 日本リウマチ学会総会・学術集会プログラム・抄録集. 2019; 63rd

LEE Wen Shi, 加藤將, 菅原恵理, 河野通大, 工藤友喜, 河野通仁, 藤枝雄一郎, 坊垣暁之, AMENGUAL Olga, 奥建志, 保田晋助, 渥美達也: Optineurin negatively regulates RANKL expression in synovial fibroblasts derived from patients with rheumatoid arthritis 日本臨床免疫学会総会プログラム・抄録集. 2019; 47th

KARINO Kohei, KONO Michihiro, KONO Michihito, ABE Nobuya, FUJIEDA Yuichiro, KATO Masaru, BOHGAKI Toshiyuki, AMENGUAL Olga, OKU Kenji, YASUDA Shinsuke, ATSUMI Tatsuya: Myofasia-dominant inflammation is a novel risk factor for rapidly progressive interstitial lung disease in dermatomyositis: a study using whole body MRI 日本リウマチ学会総会・学術集会プログラム・抄録集. 2019; 63rd

SUGAWARA Eri, KATO Masaru, KUDO Yuki, LEE Wenshi, KONO Michihito, FUJIEDA Yuichiro, BOHGAKI Toshiyuki, AMENGUAL Olga, OKU Kenji, YASUDA Shinsuke, ATSUMI Tatsuya: Risk Analysis of Pregnancy Complications in Patients with Connective Tissue Diseases: A Single-center Retrospective Study on Maternal and Fetal Outcomes 日本リウマチ学会総会・学術集会プログラム・抄録集. 2019; 63rd

LEE Wen Shi, KATO Masaru, SUGAWARA Eri, KONO Michihiro, HISADA Ryo, KUDO Yuki, KONO Michihito, FUJIEDA Yuichiro, BOHGAKI Toshiyuki, AMENGUAL Olga, OKU Kenji, YASUDA Shinsuke, ATSUMI Tatsuya: The autophagy receptor optineurin negatively regulates RANKL expression in synovial fibroblasts derived from patients with rheumatoid arthritis 日本リウマチ学会総会・学術集会プログラム・抄録集. 2019; 63rd

OHNISHI Naoki, FUJIEDA Yuichiro, KONO Michihito, KATO Masaru, OKU Kenji, BOHGAKI Toshiyuki, AMENGUAL Olga, YASUDA Shinsuke, ATSUMI Tatsuya: Prothrombin/MHC class II complexes expressed on procoagulant cells are one of the targets of pathogenic antiphospholipid antibodies 日本リウマチ学会総会・学術集会プログラム・抄録集. 2019; 63rd

Karino K, Fujieda Y, Kawamura T, Abe N, Shimoyama S, Kono M, Kato M, Yasuda S, Atsumi T: Anti-TIF1γ antibody predicted malignancy of thymic tumor with dermatomyositis as an "autoimmune tumor marker": A case report. Medicine. 2018.12; 97 (49): e13563. ( PubMed , DOI )

Abe N, Oku K, Amengual O, Fujieda Y, Kato M, Bohgaki T, Yasuda S, Mori R, Morishita E, Suzuki-Inoue K, Atsumi T: Potential therapeutics for antiphospholipid antibody associated thrombocytopenia: a systematic review and meta-analysis. Modern rheumatology. 2018.12; 30 (1): 1-21. ( PubMed , DOI )

Nakamura H, Fujieda Y, Yasuda S, Nakai M, Atsumi T: Remission of Nephrotic Syndrome After Therapy for Chronic Hepatitis C Virus Infection in a Patient With Systemic Lupus Erythematosus. Annals of internal medicine. 2018.09; 169 (5): 352-353. ( PubMed , DOI )

Shen L, Azmi NU, Tan XW, Yasuda S, Wahyuningsih AT, Inagaki J, Kobayashi K, Ando E, Sasaki T, Matsuura E: Mutants of β2-glycoprotein I: Their features and potent applications. Best practice & research. Clinical rheumatology. 2018.08; 32 (4): 572-590. ( PubMed , DOI )

Yasuda S: Emerging Targets for the Treatment of Lupus Erythematosus: There is No Royal Road to Treating Lupus. Modern rheumatology. 2018.06; 29 (1): 1-25. ( PubMed , DOI )

Nakamura H, Odani T, Yasuda S, Noguchi A, Fujieda Y, Kato M, Oku K, Bohgaki T, Sugita J, Endo T, Teshima T, Atsumi T: Autologous haematopoietic stem cell transplantation for Japanese patients with systemic sclerosis: Long-term follow-up on a phase II trial and treatment-related fatal cardiomyopathy. Modern rheumatology. 2018.01; 28 (5): 1-6. ( PubMed , DOI )

HISADA Ryo, KATO Masaru, SUGAWARA Eri, FUJIEDA Yuichiro, OKU Kenji, BOHGAKI Toshiyuki, AMENGUAL Olga, YASUDA Shinsuke, ATSUMI Tatsuya: Plasmablast Proliferation is Associated with Toll Like Receptor 7 Polymorphisms and Upregulation of Type I Interferon, Contributing to the Antibody Production in Antiphospholipid Syndrome 日本リウマチ学会総会・学術集会プログラム・抄録集. 2018; 62nd

HISADA Ryo, KATO Masaru, SUGAWARA Eri, FUJIEDA Yuichiro, OKU Kenji, BOHGAKI Toshiyuki, AMENGUAL Olga, YASUDA Shinsuke, ATSUMI Tatsuya: Plasmablast Proliferation is Associated with Toll Like Receptor 7 Polymorphisms, Contributing to the Production of Autoantibodies in Patients with Antiphospholipid Syndrome 日本免疫学会総会・学術集会記録(CD-ROM). 2018; 47

ABE Nobuya, KATO Masaru, KARINO Kohei, SHIMOYAMA Shuhei, NAKAMURA Hiroyuki, NOGUCHI Atsushi, FUJIEDA Yuichiro, OKU Kenji, BOHGAKI Toshiyuki, AMENGUAL Olga, YASUDA Shinsuke, ATSUMI Tatsuya: Evaluation of right ventricular function and prediction of prognosis by combining cardiac magnetic resonance with right heart catheterization in pulmonary hypertension associated with connective tissue diseases 日本リウマチ学会総会・学術集会プログラム・抄録集. 2018; 62nd

ABE Nobuya, OKU Kenji, OLGA Amengual, FUJIEDA Yuichiro, KATO Masaru, BOHGAKI Toshiyuki, YASUDA Shinsuke, ATSUMI Tatsuya: Efficacy and safety of possible therapeutic regimens in the management of antiphospholipid antibody associated thrombocytopenia: a systematic review and meta-analysis 日本リウマチ学会総会・学術集会プログラム・抄録集. 2018; 62nd

OHNISHI Naoki, FUJIEDA Yuichiro, KONO Michihiro, TANIMURA Syun, HISADA Ryo, SUGAWARA Eri, NAKAMURA Hiroyuki, SHIMAMURA Sanae, KATO Masaru, OKU Kenji, BOHGAKI Toshiyuki, AMENGUAL Olga, YASUDA Shinsuke, ATSUMI Tatsuya: Morbidity and mortality in patients with antiphospholipid syndrome during a 10-year period: a longitudinal cohort study of 157 Japanese patients 日本リウマチ学会総会・学術集会プログラム・抄録集. 2018; 62nd

SUGAWARA Eri, KATO Masaru, KONO Michihito, FUJIEDA Yuichiro, BOHGAKI Toshiyuki, AMENGUAL Olga, OKU Kenji, YASUDA Shinsuke, ATSUMI Tatsuya: Autophagy Promotes Citrullination of Vimentin and Its Interaction with Major Histocompatibility Complex class II in Synovial Fibroblasts 日本免疫学会総会・学術集会記録(CD-ROM). 2018; 47

OHNISHI Naoki, FUJIEDA Yuichiro, OGATA Yusuke, ABE Sawako, KONO Michihiro, TANIMURA Shun, HISADA Ryo, SUGAWARA Eri, NAKAMURA Hiroyuki, OHMURA Kazumasa, SHIMAMURA Sanae, DOI Mototsugu, SHIMIZU Yuka, KATO Masaru, OKU Kenji, BOHGAKI Toshiyuki, AMENGUAL Olga, YASUDA Shinsuke, ATSUMI Tatsuya: Prophylaxis of recurrent arterial thrombosis in patients with antiphospholipid syndrome 日本リウマチ学会総会・学術集会プログラム・抄録集. 2017; 61st

NAKAMURA Hiroyuki, OKU Kenji, ABE Sawako, OHNISHI Naoki, KONO Michihiro, TANIMURA Shun, HISADA Ryo, SUGAWARA Eri, OHMURA Kazumasa, SHIMAMURA Sanae, SHIMIZU Yuka, DOI Mototsugu, FUJIEDA Yuichiro, KATO Masaru, BOHGAKI Toshiyuki, AMENGUAL Olga, YASUDA Shinsuke, ATSUMI Tatsuya: Activation of Alternative Complement Pathway Due to Depletion of Factor H in Primary Antiphospholipid Syndrome 日本リウマチ学会総会・学術集会プログラム・抄録集. 2017; 61st

OHMURA Kazumasa, OKU Kenji, KITAORI Tamao, AMENGUAL Olga, KONO Michihiro, TANIMURA Shun, NAKAMURA Hiroyuki, SUGAWARA Eri, HISADA Ryo, SHIMAMURA Sanae, SHIMIZU Yuka, FUJIDEDA Yuichiro, KATO Masaru, BOHGAKI Toshiyuki, YASUDA Shinsuke, SUGIURA-OGASAWARA Mayumi, ATSUMI Tatsuya: Anti-C1q Antibodies Contribute to the Pathogenesis of Recurrent Pregnancy Loss via Complement Activation 日本リウマチ学会総会・学術集会プログラム・抄録集. 2017; 61st

TANIMURA Shun, FUJIEDA Yuichiro, KONO Michihiro, HISADA Ryo, SUGAWARA Eri, NAKAMURA Hiroyuki, OHMURA Kazumasa, SHIMAMURA Sanae, SHIMIZU Yuka, WATANABE Toshiyuki, SHIDA Haruki, KATO Masaru, OKU Kenji, BOHGAKI Toshiyuki, AMENGUAL Olga, HORITA Tetsuya, YASUDA Shinsuke, ATSUMI Tatsuya: Clinical Significance of plasma Presepsin levels in Patients with Connective Tissue Diseases 日本リウマチ学会総会・学術集会プログラム・抄録集. 2017; 61st

SHIMAMURA Sanae, YASUDA Shinsuke, KONO Michihiro, NAKAMURA Hiroyuki, KONO Michihito, SHIMIZU Yuka, FUJIEDA Yuichiro, KATO Masaru, OKU Kenji, BOHGAKI Toshiyuki, AMENGUAL Olga, ATSUMI Tatsuya: RasGRP4 induces proliferation of fibroblast-like synoviocytes via Ras- MAPK pathway 日本リウマチ学会総会・学術集会プログラム・抄録集. 2017; 61st

SHIMIZU Yuka, YASUDA Shinsuke, OHMURA Kazumasa, SHIMAMURA Sanae, SUGAWARA Eri, HISADA Ryo, KONO Michihiro, NAKAMURA Hiroyuki, FUJIEDA Yuchiro, KATO Masaru, OKU Kenji, BOHGAKI Toshiyuki, AMENGUAL Olga, HORITA Tetsuya, ATSUMI Tatsuya: Expression of Interferon-Inducible Mx1 Protein in Renal Tissues in Patients with Lupus Nephritis 日本リウマチ学会総会・学術集会プログラム・抄録集. 2017; 61st

Yasuda S, Horita T: [Diagnostic (Classification) Criteria and Treatment Guidelines of Collagen-vascular Diseases: Hos to Use and Cautions on Applying Them for General Physicians. Topics: VIII. Polymyalgia Rheumatica]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 2015.10; 104 (10): 2157-2162. ( PubMed )

Oku K, Amengual O, Hisada R, Oomura K, Nakagawa I, Watanabe T, Bohgaki T, Horita T, Yasuda S, Atsumi T: [The function and the significance of full-automated tests for detecting antiphospholipid antibodies]. Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology. 2015; 38 (3): 157-163. ( PubMed , DOI )

Oku K, Murashima A, Oomura K, Amengual O, Bohgaki T, Horita T, Yasuda S, Kaneko K, Nakanishi I, Nozawa K, Sugiura-Ogasawara M, Atsumi T: The participations of the physicians on the diagnosis and treatments of antiphospholipid related pregnancy morbidities in Japan: from the result of nationwide survey. Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology. 2015; 38 (6): 457-465. ( PubMed , DOI )

Kurita Takashi, Yasuda Shinsuke, Moulton Vaishali R, Kono Michihito, Koide Hideyuki, Oku Kenji, Bohgaki Toshiyuki, Amengual Olga, Horita Tetsuya, Tsokos George C, Atsumi Tatsuya: Decreased Levels Of Splicing Factor 2/Alternative Splicing Factor (SF2/ASF) Correlate With Lower Transcript Levels Of The RasGRP1 Normal Isoform In Lupus T Cells. ARTHRITIS AND RHEUMATISM. 2013.10; 65 S691.

Oku Kenji, Amengual Olga, Nakagawa Ikuma, Watanabe Toshiyuki, Kanetsuka Yusaku, Bohgaki Toshiyuki, Horita Tetsuya, Yasuda Shinsuke, Atsumi Tatsuya: Autoantibodies Against Component Of Complement One Contribute To The Complement Activation and Clinical Manifestation Of Antiphospholipid Syndrome (APS) Especially In Refractory Cases ARTHRITIS AND RHEUMATISM. 2013.10; 65 S7-S8.

Fujieda Yuichiro, Amengual Olga, Watanabe Toshiyuki, Kono Michihito, Kanetsuka Yusaku, Kurita Takashi, Odani Toshio, Otomo Kotaro, Bohgaki Toshiyuki, Horita Tetsuya, Yasuda Shinsuke, Atsumi Tatsuya: Dual Antiplatelet Therapy As Prophylaxis of Recurrent Arterial Thrombosis in Patients with antiphospholipid Syndrome. ARTHRITIS AND RHEUMATISM. 2012.10; 64 (10): S1036.

Fujieda Yuichiro, Amengual Olga, Kanetsuka Yusaku, Odani Toshio, Otomo Kotaro, Oku Kenji, Bohgaki Toshiyuki, Horita Tetsuya, Yasuda Shinsuke, Kuroki Kimiko, Maenaka Katsumi, Matsumoto Masaki, Hatakeyama Shigetsugu, Atsumi Tatsuya: Ribophorin II Is Involved in the Tissue Factor Expression Mediated by Phosphatidylserine-Dependent Antiprothrombin Antibody On Monocytes. ARTHRITIS AND RHEUMATISM. 2012.10; 64 (10): S741.

Odani Toshio, Yasuda Shinsuke, Kubota Ayaka, Nakagawa Hisako, Fujieda Yuichiro, Otomo Kotaro, Kato Masaru, Horita Tetsuya, Atsumi Tatsuya, Koike Takao: HLA-DRB5*01:05 Is a Risk Factor for Systemic Sclerosis with Interstitial Lung Disease ARTHRITIS AND RHEUMATISM. 2011.10; 63 (10): S902-S903.

Otomo Kotaro, Atsumi Tatsuya, Fujieda Yuichiro, Nakagawa Hisako, Kato Masaru, Amengual Olga, Horita Tetsuya, Yasuda Shinsuke, Matsumoto Masaki, Hatakeyama Shigetsugu, Koike Takao: Role of Apolipoprotein B100 and Oxidized Low-Density Lipoprotein in Anti-beta2 Glycoprotein I Induced Tissue Factor Expression on Monocytes ARTHRITIS AND RHEUMATISM. 2011.10; 63 (10): S6.

Amengual Olga, Atsumi Tatsuya, Kataoka Hiroshi, Horita Tetsuya, Yasuda Shinsuke, Koike Takao: Beta2glycoprotein I-Dependent anticardiolipin antibodies-induced tissue factor expression is enhanced by interferon alpha; A crucial role for lipid scramblase 1. ARTHRITIS AND RHEUMATISM. 2006.09; 54 (9): S560.

Oku Kenji, Atsumi Tatsuya, Sakai Yoshie, Kataoka Hiroshi, Horita Tetsuya, Yasuda Shinsuke, Koike Takao: Significance of hypocomplementemia in patients with primary antiphospholipid syndrome: A correlation to elevated plasma tumor necrosis factor alfa levels. ARTHRITIS AND RHEUMATISM. 2006.09; 54 (9): S796.

Yasuda Shinsuke, Atsumi Tatsuya, Horita Tetsuya, Kataoka Hiroshi, Fukae Jun, Stevens Richard L, Koike Takao: Increased expression of aberrant isoforms of Ras-Guanyl releasing protein 1 (RasGRP1) in patients with systemic lupus erythematosus (SLE). ARTHRITIS AND RHEUMATISM. 2006.09; 54 (9): S292.