1. Nobuaki Kuroiwa, Fumika Sakaue, Motoki Miura, Hirokazu Matsuno, Tetsuya Nagata, Takanori Yokota. Development of intracellular aptamer targeting ALS-associated RNA binding protein FUS. Neuro2024 2024.07.24 Fukuoka

  2. Yokota Takanori. （Chairs）NFS-01 Neuroscience Frontier Symposium 01「Exploring Early Clinical Development through Innovative Drug Modalities」. 第65回日本神経学会学術大会 2024.05.29 東京

  1. Matsubayashi Taiki, Ae Ryusuke, Kosami Koki, Tsukamoto Tadashi, Satoh Katsuya, Hamaguchi Tsuyoshi, Furukawa Fumiko, Takao Masaki, Kitamoto Tetsuyuki, Nakamura Yosikazu, Mizusawa Hidehiro, Yamada Masahito, Yokota Takanori, Sanjo Nobuo. PRNP遺伝子にP105L変異を認めるプリオン病の臨床病理学的解析(Clinicopathological analysis in prion disease with PRNP P105L mutation). Dementia Japan 2023.10.01

  2. Miura Motoki, Sakaue Fumika, Matsuno Hirokazu, Morita Kento, Hara Rintaro, Yokota Takanori. 核酸結合によるTDP-43の空間分布を介した溶解性の制御(Regulation of TDP-43 solubility via its spatial organization by nucleic acid binding). 臨床神経学 2023.09.01

  3. Ishihara Tomohiko, Ikenaka Kensuke, Takahashi Yuji, Yokota Takanori, Ishikawa Kinya, Hirano Makito, Nagai Yoshitaka, Onodera Osamu. AJA030-002　ポリグルタミン病に対するタンパク質凝集阻害剤の第II相試験(AJA030-002:Phase II Study of a Protein Aggregation Inhibitor for Polyglutamine Disease). 臨床神経学 2023.09.01

  4. Amano Eiichiro, Raveney Ben, Yokota Takanori, Yamamura Takashi, Oki Shinji. NRP-1+Th細胞はCD11c+B細胞を増殖させ脳反応性自己抗体の強力な供給源となる(NRP-1+Th cells expand CD11c+B cells that are potent source of brain reactive autoantibodies). 臨床神経学 2023.09.01

  5. Iwase Ryo, Ishiguro Taro, Hasegawa Juri, Iwata Hara Rintaro, Nagata Tetsuya, Yokota Takanori. RNA-DNAヘテロG4構造誘導ASOを用いたDMDエクソンスキッピングに対する新戦略(A new strategy for DMD exon skipping with RNA-DNA hetero-G4 structure inducing ASOs). 臨床神経学 2023.09.01

  6. Yanagidaira Mitsugu, Nagata Testuya, Hasegawa Juri, Ishii Satoshi, Ebihara Satoe, Yokota Takanori. PMO/RNAヘテロ2本鎖を用いたCNSにおけるスプライス制御の新規技術(Novel technology for splice modulation in CNS by PMO/RNA heteroduplex). 臨床神経学 2023.09.01

  7. Yokote Hiroaki, Miyazaki Yusei, Toru Shuta, Nishida Yoichiro, Hattori Takaaki, Niino Masaaki, Sanjo Nobuo, Yokota Takanori. 日本人多発性硬化症患者の脳容積減少を抑制する有効性の高い治療法(High-efficacy therapy reduces brain volume loss in Japanese patients with multiple sclerosis). 臨床神経学 2023.09.01

  8. Kuroda Takayuki, Yoshioka Kotaro, Su Su Lei Mon , Sakamoto Toshihiro, Katsuyama Maho, Yoshida-Tanaka Kie, Iwata-Hara Rintaro, Yamaguchi Takao, Nagata Tetsuya, Obika Satoshi, Yokota Takanori. アンチセンスオリゴヌクレオチドの神経毒性を克服するための化学的改良の開発(Development of chemical modifications to overcome neurotoxicity of antisense oligonucleotide). 臨床神経学 2023.09.01

  9. 常 詩晨, 田中 敏博, 稲澤 譲治, 水澤 英洋, 三條 伸夫, 横田 隆徳, 石川 欽也. 神経疾患の遺伝的リスク評価. 臨床神経学 2023.09.01

  10. Yokota Takanori. 神経疾患に関する遺伝子治療と細胞療法　神経疾患を標的としたDNA/RNAヘテロ2本鎖オリゴヌクレオチド(Gene and cell therapy for neurological diseases　DNA/RNA heteroduplex oligonucleotides for neurological diseases). 臨床神経学 2023.09.01

  11. Hattori Takaaki, Kitsuka Narumi, Sanjo Nobuo, Oyama Jun, Yoshii Toshitaka, Okawa Atsushi, Yokota Takanori. 硬膜閉鎖後の表在性シデローシスにおける前側頭葉の逆説的なMRI増悪(Paradoxical MRI exacerbation in anterior temporal lobe in superficial siderosis after dural closure). 臨床神経学 2023.09.01

  12. Miura Motoki, Sakaue Fumika, Matsuno Hirokazu, Morita Kento, Hara Rintaro, Yokota Takanori. 核酸結合によるTDP-43の空間分布を介した溶解性の制御(Regulation of TDP-43 solubility via its spatial organization by nucleic acid binding). 臨床神経学 2023.09.01

  13. Ono Daisuke, Kawai Honami, Kuwahara Hiroya, Yokota Takanori. 機械学習アプリケーションによる腓腹神経生検の自動whole slide解析(Automated Whole Slide Analysis of Sural Nerve Biopsy by Machine Learning Application). 臨床神経学 2023.09.01

  14. Yokote Hiroaki, Miyazaki Yusei, Toru Shuta, Nishida Yoichiro, Hattori Takaaki, Niino Masaaki, Sanjo Nobuo, Yokota Takanori. 日本人多発性硬化症患者の脳容積減少を抑制する有効性の高い治療法(High-efficacy therapy reduces brain volume loss in Japanese patients with multiple sclerosis). 臨床神経学 2023.09.01

  15. Ichinose Keiko, Li Fuying, Ishibashi Satoru, Iwasawa Eri, Suzuki Motohiro, Yoshida Kie, Yoshioka Kotaro, Nagata Tetsuya, Mogushi Kaoru, Yokota Takanori. 脂質結合DNA/RNAヘテロ2本鎖オリゴヌクレオチドの急性虚血脳への効果的な送達(Effective delivery of lipid conjugated DNA/RNA heteroduplex oligonucleotide to acute ischemic brain). 臨床神経学 2023.09.01

  16. Motoki Miura. Nucleic acid binding regulates TDP-43 solubility via its spacial arrangement. 2023.09 Malaysia

  17. Motoki Miura. Regulation of TDP-43 solubility via its spatial organization by nucleic acid binding.. 2023.06.01

  1. Yokota T. Blood-Brain-Barrier(BBB)penetrating DNA/RNA Heteroduplex Oligonucleotide regulating CNS genes by systemic administration. ANA2022 2022.10.23 CHICAGO

  2. Yokota T. Blood-Brain-Barrier penetrating DNA/RNA Heteroduplex Oligonuclotide (HDO)can regulate genes of microglia and lymphocytes by systemic administration. The 34th annual meeting of the Japanese Society for Neuroimmunology 2022.10.21 長崎

  3. Hirata Kosei, Matsuoka Kiwamu, Tagai Kenji, Endo Hironobu, Kokubo Naomi, Tatebe Harutsugu, Zhang Hong, Shinotoh Hitoshi, Takahata Keisuke, Ono Maiko, Obata Takayuki, Kawamura Kazunori, Zhang Ming-Rong, Shimada Hitoshi, Tokuda Takahiko, Yokota Takanori, Takado Yuhei, Higuchi Makoto. タウオパチーにおけるアストロサイトに関連した脳エネルギー代謝の変化(Altered brain energy metabolism related to astrocytes in tauopathies). 臨床神経学 2022.10.01

  4. Sano Tatsuhiko, Nagata Tetsuya, Ebihara Satoe, Yoshida-Tanaka Kie, Mochizuki Hideki, Hasegawa Masato, Yokota Takanori. ASOの局所投与はマウスにおける異常αシヌクレイン病態の伝播を防ぐ(Local administration of ASO prevents the propagation of abnormal α-synuclein pathology in mice). 臨床神経学 2022.10.01

  5. Aoki Hanako, Higashi Miwa, Okita Michi, Ishikawa Kinya, Yokota Takanori. Pentanucleotide repeat(TTCCA)nによるSCA31の小脳におけるTK2の発現と機能(Expression and function of TK2 in the cerebellum of SCA31 caused by pentanucleotide repeat (TTCCA)n). 臨床神経学 2022.10.01

  6. Nishi Rieko, Ohyagi Masaki, Nagata Tetsuya, Mabuchi Yo, Yokota Takanori. DNA/RNAヘテロ二重鎖オリゴヌクレオチドによる活性化ミクログリアとマクロファージの制御(Regulation of activated microglia and macrophages by DNA/RNA heteroduplex oligonucleotides). 臨床神経学 2022.10.01

  7. Higashi Miwa, Okita Michi, Sato Nozomu, Aoki Hanako, Komatsu Takumi, Asaka Meiko, Yanagihara Dai, Yokota Takanori, Ishikawa Kinya. SCA31ペンタヌクレオチド反復配列BACトランスジェニックマウスの運動表現型(Motor phenotype of BAC transgenic mice with SCA31 pentanucleotide repeats). 臨床神経学 2022.10.01

  8. Okamoto Tomoko, Sato Wakiro, Lin Youwei, Shimizu Yuko, Nishida Yoichiro, Yokota Takanori, Ishizuka Takami, Nakamura Harumasa, Takahashi Yuji, Yamamura Takashi. 糖脂質OCH-NCNP1　多発性硬化症患者を対象とした第II相臨床試験プロトコール(Glycolipid OCH-NCNP1: Protocol of Phase II Clinical Trial for Patients with Multiple Sclerosis). 臨床神経学 2022.10.01

  9. Ishihara Tomohiko, Ikenaka Kensuke, Takahashi Yuji, Yokota Takanori, Ishikawa Kinya, Hirano Makito, Nagai Yoshitaka, Onodera Osamu. ポリグルタミン病に対するタンパク質凝集阻害剤の第II相試験(Phase II Study of a Protein Aggregation Inhibitor for Polyglutamine Disease). 臨床神経学 2022.10.01

  10. Sanjo Nobuo, Amano Akiko, Araki Wataru, Anraku Yasutaka, Nakakido Makoto, Matsubara Etsuro, Hirata Kousei, Nagata Tetsuya, Tsumoto Kouhei, Kataoka Kazunori, Yokota Takanori. ナノミセル化抗アミロイドβオリゴマー断片抗体のAD病態における有効性(Efficacy of nanomicelle-encapsulated anti-amyloid β oligomer fragment antibody in AD pathology). 臨床神経学 2022.10.01

  11. Kawabata Sakino, Toide Nozomi, Nagata Tetsuya, Yoshida-Tanaka Kie, Ihara Kensuke, Yokota Takanori. トリコサン酸結合DNA/RNAヘテロ二重鎖オリゴヌクレオチドはマウスの筋において非常に効率的である(Tricosanoic acid conjugated DNA/RNA heteroduplex oligonucleotide is highly efficient in mouse muscle). 臨床神経学 2022.10.01

  12. Hasegawa Juri, Nagata Tetsuya, Ihara Kensuke, Tanihata Jun, Yokota Takanori. エクソンスキッピングの新しい治療法としての脂質結合ヘテロ二重鎖オリゴヌクレオチドの開発(Development of Lipid-conjugated heteroduplex oligonucleotide as a new treatment for exon skipping). 臨床神経学 2022.10.01

  13. Okamoto Tomoko, Sato Wakiro, Lin Youwei, Shimizu Yuko, Nishida Yoichiro, Yokota Takanori, Ishizuka Takami, Nakamura Harumasa, Takahashi Yuji, Yamamura Takashi. 糖脂質OCH-NCNP1　多発性硬化症患者を対象とした第II相臨床試験プロトコール(Glycolipid OCH-NCNP1: Protocol of Phase II Clinical Trial for Patients with Multiple Sclerosis). 臨床神経学 2022.10.01

  14. Amano Eiichiro, Sato Wakiro, Yamaguchi Hiromi, Yokota Takanori, Yamamura Takashi. 視神経脊髄炎患者におけるCD11chigh B細胞の増加(CD11chigh B cell expansion in patients with neuromyelitis optica). 臨床神経学 2022.10.01

  15. Tojo Nakayama, Timothy Yu. アンチセンスオリゴを用いた神経疾患に対する個別化医療の取り組み. Neuro2022(第45回日本神経科学大会・第65回日本神経化学会大会・第32回日本神経回路学会大会) 2022.07.03 沖縄

  16. Aoki H,Higashi M,Okita M,Ishikawa K,Yokota T. Expression and function of TK2 in the cerebellum of SCA31 caused by pentanucleotide repeat (TTCCA). 第６３回日本神経学会学術大会 2022.05.20 東京

  17. Higashi M,Okita M,Sato N,Aoki H,Komatsu T,Asaka M,Yanagihara D,Yokota T,Ishikawa K. Motor phenotype of BAC transgenic mice with SCA31 pentanucleotide repeats. 第６３回日本神経学会学術大会 2022.05.20 東京

  18. Tojo Nakayama, Timothy Yu. Early forays into individualized genomic medicine with antisense oligonucleotides. 第63回日本神経学会学術大会 2022.05.19 東京

  19. Ishihara T,Ikenaka K,Takahashi Y,Yokota T,Ishikawa K,Hirano M,Nagai Y,Onodera O. Phase Ⅱ study of a Protein Aggregation Inhibitor for Polyglutamine Disease. 第６３回日本神経学会学術大会 2022.05.19 東京

  20. Sanjo N,Amano A,Araki W,Anraku Y,Nakakido M,Matsubara EHirata K,Nagata T,Tsumoto K,Kataoka K,Yokota T,. Efficacy of nanomicelle-encapsulated anti-amyloid β oligomer fragment antibody in AD pathology. 第６３回日本神経学会学術大会 2022.05.19 東京

  21. Kawabata S,Toide N,Nagata T,Yoshida-tanaka K,Ihara K,Yokota T,. Tricosanoic acid conjugated DNA/RNA heteroduplex oligonucleotide is highly efficient in mouse muscle. 第６３回日本神経学会学術大会 2022.05.19 東京

  22. Amano E,Sato W,Yamaguchi H,Yokota T,Yamamura T. CD11chigh B cell expansion in patients with neuromyelitis optica. 第６３回日本神経学会学術大会 2022.05.19 東京

  23. Hirata K,Matsuoka K,Tagai K,Endo H,Kokubo N,Tatebe H,Zhang H,Shinotoh H,Takahata K,Ono M,Obata T,Kawamura K,Zhang M,Shimada H,Tokuda T,Yokota T,Takado Y,Higuchi M. Aitered brain energy metabolism related to astrocytes in tauopathies. 第６３回日本神経学会学術大会 2022.05.18 東京

  24. Nishi R,Ohyagi M,Nagata T,Mabuchi Y,Yokota T. Regulation of activated microglia and macrophages by DNA/RNA heteroduplex oligonucleotides. 第６３回日本神経学会学術大会 2022.05.18 東京

  25. Hasegawa J,Nagata T,Ihara K,Tanihata J,Yokota T. Development of Lipid-conjugated heteroduplex oligonucleotide as a new treatment for exon skipping. 第６３回日本神経学会学術大会 2022.05.18 東京

  26. Sano T,Nagata T,Ebihara S,Yoshida-tanaka K,Mochizuki H,Hasegawa M,Yokota T. Local administration of ASO prevents the propagation of abnormal α-synuclein pathology in micein pathology in mice. 第６３回日本神経学会学術大会 2022.05.18 東京

  27. Tamaki Kana, Nishida Yoichiro, Sanjo Nobuo, Yokota Takanori. A patient with generalized myasthenia gravis facing an impending crisis triggered by early fast-acting treatment. Clinical and Experimental Neuroimmunology 2022.05.01

  28. Noda K, Nosaka N, Hara N, Yokota T, Shigemitsu H, Takahashi H. We Should Pay Attention to "Referred Pain": A Case of Acute Myocardial Infarction That Masked and Delayed the Diagnosis of Esophageal Perforation. Internal Medicine 2022.04.01

  29. 中村圭佑,金澤俊郎,関口輝彦,桑原宏哉,石川欽也,横田隆徳,西野一三,大久保卓哉. DNM2遺伝子新規変異を認めた中心核ミオパチーが疑われる76歳女性例. 2022.03.05

  30. 大谷 泰,赤座実穂,叶内 匡,夏井洋和,川端茂徳,渡部泰士,石田洸樹,宮野由貴,足立善昭,関原謙,横田隆徳. 生体磁場計測装置を用いた単一の運動単位の電気活動評価. 第14回CBIR/ONSA/大学院セミナー共済　若手インスパイアシンポジウム 2022.02.17

  31. Ohara M,Nagata T,Iwata Hara R,Takagi K,Sato K,Maeda Y,Wada T,Yokota T. Cationic oligopeptides enhance the therapeutic potential of ligand-conjug DNA/RNA heteroduplex . 第14回CBIR/ONSA/大学院セミナー共済　若手インスパイアシンポジウム 2022.02.17

  1. Takanori Yokota. Development of heteroduplex oligonucleotides(HDO)for contral nervous system by systemic administration. PACIFICHEM 2021 2021.12.17 USA　web

  2. Fumika Sakaue, Motoki Miura, Taro Ishiguro, Hirokazu Matsuno, Tatsuhiko Sano, Ryo Iwase, Rintaro Hara, Takeshi Wada, Tetsuya Nagata, Takanori Yokota. Chemically modified short oligonucleotide regulates LLPS and reduces TDP-43 pathology in vivo. Pan-Asia Consortium for Treatment and Research in ALS 2021 2021.09.17 Web

  3. Jia Chunyan, Yoshioka Kotaro, Su Su Lei Mon , Katsuyama Maho, Tanaka-Yoshida Kie, Nagata Tetsuya, Yokota Takanori. Hetereoduplex oligonucleotiedeによるCSFを介した各種急性中枢神経毒性の軽減効果(Hetereoduplex oligonucleotiede mitigates various types of acute CNS toxicities via CSF route). 臨床神経学 2021.09.01

  4. Su Su Lei Mon , Yoshioka Kotaro, Jia Chunyan, Kunieda Taiki, Asami Yutaro, Yoshida-Tanaka Kie, Piao Wenying, Kuwahara Hiroya, Nishina Kazutaka, Nagata Tetsuya, Yokota Takanori. オーバーハング2本鎖核酸の脳室内投与による効果増強と毒性の緩和(Overhanging duplex oligonucleotide enhances potency and mitigates toxicity intracerebroventricularly). 臨床神経学 2021.09.01

  5. Miura Motoki, Sakaue Fumika, Ishiguro Taro, Iwase Ryo, Sano Tatsuhiko, Hara Rintaro, Wada Takeshi, Nagata Tetsuya, Yokota Takanori. TDP-43特異的アプタマーによるTDP-43トランスジェニックマウスにおけるALS表現型の改善(TDP-43-specific aptamer rescues ALS phenotype in TDP-43 transgenic mice). 臨床神経学 2021.09.01

  6. Fumika Sakaue. LLPS – A new therapeutic target for neurodegenerative disease. the 44th Annual Meeting of the Japan Neuroscience Society 2021.07.29 Kobe

  7. Takaaki Hattori, Masahiro Ohara, Tatsuhiko Yuasa, Reo Azuma, Qingmeng Chen, Satoshi Orimo, Takanori Yokota. Callosal angle at splenium is phenotypicmarker of idiopathic normal pressure hydrocephalus. The 15th Congress of the Movement Disorder Society of Japan 2021.07.02

  8. Shinya Akiko, Takahashi Makoto, Sato Nozomu, Nishida Yoichiro, Inaba Akira, Inaji Motoki, Yokota Takanori, Orimo Satoshi. 髄腔内バクロフェン療法が成功した痙性不全対麻痺として現れた眼・歯・指異形成症(Oculo-dento-digital Dysplasia Presenting as Spastic Paraparesis Which Was Successfully Treated by Intrathecal Baclofen Therapy). Internal Medicine 2021.07.01

  9. Chunyan Jia，Kotaro Yoshioka，Su Su Lei Mon，Maho Katsuyama，Kie Tanaka-yoshida，Tetsuya Nagata，Takanori Yokota. Hetereoduplex oligonucleotiede mitigates various types of acute CNS toxicities via CSF route. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.21 Kyoto

  10. Takaaki Hattori, Richard Reynolds, Silvina Horovitz, Codrin Lungu, Eric Wassermann, Mark Hallett. Decreased functional integrity within striatum and sensorimotor network in Parkinson disease. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.20 Kyoto

  11. Masahiro Ohara，Takaaki Hattori，Taiki Matsubayashi，Kosei Hirata，Qingmeng Chen，Satoko Kina，Koji Morito，Kaoru Shimano，Takanori Yokota. Inter-regional balance within striatum affects cognition and dual-task gait in Parkinson's disease. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.20 Kyoto

  12. Taiki Matsubayashi，Takaaki Hattori，Masahiro Ohara，Kosei Hirata，Qingmeng Chen，Sato ko Kina，Koji Morito，Kaoru Shimano，Takanori Yokota. Dopaminergic denervation in executive striatum predicts response to L-dopa in Parkinson's disease. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.20 Kyoto

  13. Yurie Nose，Ikuko Uwano，Ukihide Tateishi，Makoto Sasaki，Takanori Yokota，Nobuo Sanjo. Clinical and radiological efficacy of deferiprone in post-operative superficial siderosis. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.20 Kyoto

  14. Motoki Miura，Fumika Sakaue，Taro Ishiguro，Ryo Iwase，Tatsuhiko Sano，Rintaro Hara，Takeshi Wada，Tetsuya Nagata，Takanori Yokota. TDP-43-specific aptamer rescues ALS phenotype in TDP-43 transgenic mice. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.19 Kyoto

  15. Hanako Aoki，Miwa Higashi，Michi Okita，Takanori Yokota，Kinya Ishikawa. Expression of thymidine kinase 2 gene in human SCA31 cerebellum. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.19 Kyoto

  16. Miwa Higashi，Michi Okita，Hanako Aoki，Takashi Ishii，Tetsuya Nagata，Taro Ishiguro，Takanori Yokota，Kinya Ishikawa. What are the roles of TGGAA penta-nucleotide repeats as bidirectional transcripts in SCA31?. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.19 Kyoto

  17. Su Su Lei Mon，Kotaro Yoshioka，Chunyan Jia，Taiki Kunieda，Yutaro Asami，Kie Yoshida-tanaka，Wenying Piao，Hiroya Kuwahara，Kazutaka Nishina，Tetsuya Nagata，Takanori Yokota. Overhanging duplex oligonucleotide enhances potency and mitigates toxicity intracerebroventricularly. 62nd Annual Meeting of the Japanese Society of Neurology  2021.05.19 Kyoto

  18. Motoki Miura. TDP-43-specific aptamer rescues ALS phenotype in TDP-43 transgenic mice. 2021.05.19

  1. Jia Chunyan, Yoshioka Kotaro, Mon Su Su Lei, Tanaka Kie, Nagata Tetsuya, Yokota Takanori. CNS疾患に対するヘテロ二重鎖オリゴヌクレオチド使用による治療指標の改善(Hetereoduplex oligonucleotides technology improves therapeutic index for CNS diseases). 臨床神経学 2020.11.01

  2. Yoshioka Kotaro, Kunieda Taiki, Asami Yutaro, Tanaka Kie, Piao Wenying, Kuwahara Hiroya, Nishina Kazutaka, Nagata Tetsuya, Yokota Takanori. オーバーハングしたヘテロ二重鎖オリゴヌクレオチドを用いたFAPのトランスフェリンを介した送達による治療(Treatment for FAP with overhanging heteroduplex oligonucleotides by transferrin-mediated delivery). 臨床神経学 2020.11.01

  3. Yokote Hiroaki, Toru Shuta, Nishida Yoichiro, Hattori Takaaki, Sanjo Nobuo, Yokota Takanori. 多発性硬化症患者の血清アミロイドAタンパク質値と皮質容積の関連性(Association between serum amyloid A and cortical volume in patients with multiple sclerosis). 臨床神経学 2020.11.01

  4. Yokote Hiroaki, Toru Shuta, Nishida Yoichiro, Hattori Takaaki, Sanjo Nobuo, Yokota Takanori. 多発性硬化症患者の血清アミロイドAタンパク質値と皮質容積の関連性(Association between serum amyloid A and cortical volume in patients with multiple sclerosis). 臨床神経学 2020.11.01

  5. Koki Kosami, Ryusuke Ae, Yosikazu Nakamura, Tsuyoshi Hamaguchi,Tadashi Tsukamoto, Ichiro Takumi, Nobuo Sanjo, Tetsuyuki Kitamoto, Masahito Yamada, Hidehiro Mizusawa. Descriptive epidemiology of prion disease in Japan based on national surveillance (1999-2019).. World Congress of Epidemiology 2020 2020.09.13 Melbourne, Australia

  6. Ishikawa K,Higashi M,Okita M,Aoki H,Asaka M,Ishiguro T,Sato N,Nagai Y,Yanagihara D,Yokota T. Pathogenesis of spinocerebellar ataxia type31(SCA31). 61st Annual Meeting of the Japanese Society of Neurology 2020.09.02 Okayama

  7. Yokota T,Nagata T,Dwyer C,Yoshida K,Yoshioka K,Seth P,Rigo F,Bennett F. Development of BBB-penetrating heteroduplex oligonucleotides(HDO). 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

  8. Yoshioka K,Kunieda T,Asami Y,Tanaka K,Piao W,Kuwahara H,Nishina K,Nagata T,Yokota T. Treatment for FAP with overhanging heteroduplex oligonucleotides by transferrin-mediated delivery. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

  9. Iwase R,Sanjo N,Ishiguro T,Yokota T. Clinical characteristics and pathophysiology of a rare muscle atrophy in superficial siderosis. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

  10. Jia C,Yoshioka K,Lei Mon S,Tanaka K,Nagata T,Yokota T. Heteroduplex Oligonucleotides technology improves therapeutic index for CNS diseases. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31

  11. Maruoka H,Hattori T,Orimo S,Yokota T. Graph theoretical analysis of structural brain network of Alzheimer's disease patients. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

  12. Ohyagi M,Nagata T,Ihara K,Nishi R,Mabuchi Y,Akazawa C,Yokota T. New therapeutics strategy for multiple sclerosis by DNA/RNA heteroduplex oligonucleotide technology. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

  13. Higashi M,Okita M,Sato N,Asaka M,Ishii T,Aoki H,Ishiguro T,Yanagihara D,Yokota T.Ishikawa K. SCA31 transgenic mice show pathologic features similar to human patients. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

  14. Sano T,Nagata T,Tanaka K,Ebihara S,Mochizuki H,Hasegawa M,Yokota T. Inhibition of SNCA Propagation by locally injected ASO in wt mice. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31

  15. Asami Y,Nagata T,Yoshioka K,Kunieda T,Yoshida-Tanaka K,Yokota T. Efficient gene suppression by DNA/DNA double-stranded oligonucleotide in vivo. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31

  16. Akaza M,Kawabata S,Watanabe T,Miyano Y,Mizuguchi R,Kaminaka S,Iida S,Sasaki T,Adachi Y,Sekihara K,Sumi Y,Okawa A,Yokota . The evaluation of nerve activity using magnetic field measurement and positional information by US. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

  17. Irioka T,Motomura M,Igarahi S,Takahahi Y,Iwase R,Otani T,Kitanosono H,Shiraihi H,Iizuka T,Yokota T. Calcium channels antibody-associated paraneoplastic disorders other than Lambert-Eaton syndrome. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

  18. Nishi R,Ohyagi M,Nagata T,Mabuchi Y,Yokota T. DNA/RNA heteroduplex oligonucleotide technology for regulating activated microglia and macrophages. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31

  19. Aoki H,Higashi M,Okita M,Yokota T,Ishikawa K. Expression of thymidine kinase 2 and mitochondrial proteins in SCA31 human brains. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

  20. Yokote H,Toru S,Nishida Y,Hattori T,Sanjo N,Yokota T. Association between serum amyloid A and cortical volume in patients with multiple sclerosis. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31 Okayama

  21. Ohara M,Takagi K,Yoshida K,Maeda Y,Hara R,Sato K,Nagata T,Wada T,Yokota T. Development of antidote for therapeutic oligonucleotides which reduces the acute toxicity. 61st Annual Meeting of the Japanese Society of Neurology 2020.08.31

  22. Takanori Yokota. New Stage of DNA/RNA Heteroduplex Oligonucleotide. Asia TIDES:Oligonucleotide & Peptide Therapeutics 2020.02.24 kyoto

  1. Kotaro Yoshioka. Heteroduplex-Oligonucleotides　for　Highly　Efficient　Silencing　of　microRNA　through　a　Novel　intracellular Mechanism. 2019　Oligonucleotides　Meeting 2019.11.16 Munich

  2. Takanori Yokota. Systemically Administered DNA/RNA Heteroduplex Oligonucleotides That Can Efficiently Regulate CNS Genes*. TIDES Europe2019:Oligonucleotide &Peptide Therapeutics 2019.11.13 Amsterdam

  3. Amano A,Sanjo N,Nakakido M,Tsumoto K,Matsubara E,Furukawa F,Nishida Y,Saito T,Saido T,Yokota T,. Quantitative evaluation of Aβ oligomer in mouse brain using dot blot method. 第38回日本認知症学会学術集会 2019.11.07 新宿

  4. Yoshioka Kotaro, Su Su Lei Mon , Jia Chunyan, Yamada Hiroki, Asami Yutaro, Tanaka Kie, Wenying Piao, Kuwahara Hiroya, Nishina Kazutaka, Nagata Tetsuya, Yokota Takanori. CNSを標的としたオーバーハングヘテロ二2本鎖核酸を用いた新しいアンチセンスオリゴヌクレオチド治療(A novel antisense oligonucleotide therapy by overhanging heteroduplex oligonucleotide targeting CNS). 臨床神経学 2019.11.01

  5. Iwase Ryo, Irioka Takashi, Takahashi Yuko K., Igarashi Susumu, Otani Tai, Soga Kazumasa, Yokota Takanori. 血管内リンパ腫(IVL)3症例の臨床および神経放射線学的研究(Clinical and neuroradiological study of 3 patients with intravascular lymphoma(IVL)). 臨床神経学 2019.11.01

  6. 高橋 直, 宮本 翔平, 三條 伸夫, 横田 隆徳. 第三脳室幅は慢性進行型神経ベーチェット病の高感度マーカーである(Width of the third ventricle is high-sensitive marker for chronic progressive neuro-Behcet's disease). 臨床神経学 2019.11.01

  7. Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Yokota Takanori. 疾患修飾療法時代の進行性多巣性白質脳症　炎症の制御と免疫システムの制御はPMLの良好な予後と関連している(Progressive multifocal leukoencephalopathy in the era of disease-modifying therapies　A controlled inflammation and a regulatory immune system are associated with better prognosis of PML). 臨床神経学 2019.11.01

  8. Hirata Kosei, Hattori Takaaki, Chen Qingmeng, Ohara Masahiro, Kina Satoko, Yokota Takanori. 線条体でのドーパミン枯渇とパーキンソン病患者におけるストライド長の変動との相関(Striatal dopamine depletion correlates with variability of stride length in Parkinson's disease). 臨床神経学 2019.11.01

  9. Kim Yangsu, Iwase Ryo, Otani Tai, Igarashi Susumu, Soga Kazumasa, Irioka Takashi, Yokota Takanori. 血液透析患者における水痘・帯状疱疹ウイルス脳炎後の帯状疱疹(Varicella-zoster virus encephalitis followed by herpes zoster in hemodialysis patients). 臨床神経学 2019.11.01

  10. Akaza Miho, Kawabata Shigenori, Watanabe Taishi, Hasegawa Yuki, Iida Shintaro, Sasaki Toru, Adachi Yoshiaki, Sekihara Kensuke, Kanouchi Tadashi, Sumi Yuki, Okawa Atsushi, Yokota Takanori. 脊磁計によるC8神経根症の診断(Diagnosis of C8 radiculopathy by magnetospinogram). 臨床神経学 2019.11.01

  11. Irioka Takashi, Motomura Masakatsu, Uchihara Toshiki, Shintaku Hiroshi, Ishikawa Kinya, Igarashi Susumu, Majima Takamasa, Takahashi Yuko K., Iwase Ryo, Otani Tai, Kitanosono Hiroko, Shiraishi Hirokazu, Tsuura Yukio, Yokota Takanori. カルシウムチャネル抗体関連小脳失調症患者の臨床病理学的研究(Clinicopathological study of a patient with calcium channels antibody-associated cerebellar ataxia). 臨床神経学 2019.11.01

  12. Yokota Takanori. トランスレーショナルリサーチ後の時代における運動ニューロン疾患　ALS治療のオリゴヌクレオチド薬(Motor neuron diseases in the era after translational research　Oligonucleotide drug for treatment of ALS). 臨床神経学 2019.11.01

  13. Ishiguro Taro, Yokota Takanori, Ishikawa Kinya, Nagai Yoshitaka, Petrucelli Leonard. ショウジョウバエのSpt4ノックダウンはSCA31関連の伸長UGGAAリピート誘発毒性を抑制する(Spt4 knockdown suppressed SCA31-linked expanded UGGAA repeat-induced toxicity in Drosophila). 臨床神経学 2019.11.01

  14. Otani Tai, Iwase Ryo, Takahashi Yuko K., Soga Kazumasa, Kim Yangsu, Igarashi Susumu, Kaneko Kimihiko, Takahashi Toshiyuki, Irioka Takashi, Yokota Takanori. MOG抗体陽性中枢神経疾患の多様性(A Variety of Myelin Oligodendrocyte Glycoprotein Antibody Positive Central Nervous System Disorders). 臨床神経学 2019.11.01

  15. 1. Yoshioka K, Kunieda T, Asami Y, Huijia G, Miyata H, Tanaka K, Sujino Y, Piao W, Kuwahara H, Nishina K, Iwata-Hara R, Nagata T, Wada T, Obika S, Yokota T. . Heteroduplex-oligonucleotides for highly efficient silencing of microRNA through a novel intracellular mechanism. 15th Annual Meeting of the Oligonucleotide Therapeutics Society 2019.10.16

  16. 坂井健二、三條伸夫、村井弘之、岩崎靖、濱野忠則、本間真理、中村好一、原田雅史、水澤英洋、山田正仁.. Extension patterns of hyperintensity on diffusion-weighted MR images in dura mater graft-associated CJD.. 第24回日本神経感染症学会総会・学術大会 2019.10.11 東京

  17. 藤田　明日菜、三條　伸夫、西田　陽一郎、今井　耕輔、松林　泰毅、森尾　友宏、横田　隆徳.. 非血縁者間同種造血幹細胞移植に伴う免疫異常を背景とした重症肺炎球菌性髄膜炎の37歳女性例.. 第24回日本神経感染症学会総会・学術大会 2019.10.11 東京

  18. Yokota T. BBB-penetrating DNA/RNA heteroduplex oligonucleotide efficiently regulating CNS gene. Tokyo Medical and Dental University-Taipei Medical University Joint Symposium on Medical Innovation 2019.10.05 Taipei

  19. Taiki Matsubayashi, Miho Akaza, Nobuo Sanjo, Tsuyoshi Hamaguchi, Yuichi Hayashi, Takayoshi Shimohata, Masahito Yamada, Takanori Yokota. Focal sharp waves are specific in the early stage of MM2 cortical form of sCJD . Asian Pacific Prion Symposium 2019 2019.10.03 埼玉

  20. Taiki Matsubayashi, Miho Akaza, Nobuo Sanjo, Tsuyoshi Hamaguchi, Yuichi Hayashi, Takayoshi Shimohata, Masahito Yamada, Takanori Yokota.. Focal sharp waves are specific in the early stage of MM2 cortical form of sCJD.. Asia Pacific Prion Symposium 2019 2019.10.03 埼玉

  21. Tsuyoshi Hamaguchi, Kenji Sakai, Atsushi Kobayashi, Tetsuyuki Kitamoto, Ryusuke Ae, Yosikazu Nakamura, Nobuo Sanjo, Kimihito Arai, Mizuho Koide, Fumiaki Katada, Masafumi Harada, Hiroyuki Murai, Shigeo Murayama, Tadashi Tsukamoto, Hidehiro Mizusawa, Masahito Yamada. . Characterization of “sporadic CJD” with history of neurosurgery to identify potentially iatrogenic cases.. Asia Pacific Prion Symposium 2019 2019.10.03 埼玉

  22. Amano Akiko, Sanjo Nobuo, Nakakido Makoto, Tsumoto Kouhei, Matsubara Etsuro, Furukawa Fumiko, Nishida Yoichiro, Saito Takashi, Saido Takaomi, Yokota Takanori. ドットブロット法を用いたマウス脳におけるAβオリゴマーの定量的評価(Quantitative evaluation of Aβ oligomer in mouse brain using dot blot method). Dementia Japan 2019.10.01

  23. Takaaki Hattori. Neural correlates of compensatory process and impaired working memory in Parkinson’s disease during disease progression. 23rd International Congress of Parkinson's Disease and Movement Disrders 2019.09.25 Nice

  24. 天野晶子,三條伸夫,仲木戸誠,津本浩平,松原悦朗,古川迪子,西田陽一郎,斉藤貴志,西道隆臣,横田隆徳. ドットブロット法を用いたマウス脳中アミロイドβオリゴマーの定量法評価. 第7回日本アミロイドーシス学会学術集会 2019.08.30 東京

  25. Ono Daisuke, Shishido-Hara Yukiko, Mizutani Saneyuki, Mori Yoko, Ichinose Keiko, Watanabe Mutsufusa, Tanizawa Tohru, Yokota Takanori, Uchihara Toshiki, Fujigasaki Hiroto. 進行性多巣性白質脳症(PML)における脱髄病変の発症　死後脳MRIと神経病理の比較(Development of demyelinating lesions in progressive multifocal leukoencephalopathy(PML): Comparison of magnetic resonance images and neuropathology of post-mortem brain). NEUROPATHOLOGY 2019.08.01

  26. Amano A,Sanjo N,Nakakido M,Tsumoto K,Matsubara E,Nishida Y,Hattori T,Nagata T,Tomiyama T,Yokota T. Quantitative measurement of amyloid-beta oligomer in mouse brain using dot blot assay. ALZHEIMER'S ASSOCIATION INTERNATIONAL CONFERENCE2019 2019.07.16 LOS ANGELES

  27. Akiko Amano, Nobuo Sanjo, Makoto Nakakido, Kouhei Tsumoto, Etsuro Matsubara, Yoichiro Nishida, Takaaki Hattori, Tetsuya Nagata, Takami Tomiyama, Takanori Yokota.. Quantitative measurement of amyloid beta oligomer in mouse brain using dot blot assay.. Alzheimer's Association International Conference 2019 2019.07.14 Los Angeles, CA, USA,

  28. Iwase Ryo, Irioka Takashi, Takahashi Yuko K, Igarashi Susumu, Otani Tai, Soga Kazumasa, Yokota Takanori. Clinical and neuroradiological study of 3 patients with intravascular lymphoma(IVL). 第60回日本神経学会学術大会 2019.05.25

  29. Otani Tai, Iwase Ryo, Takahashi Yuko K, Soga Kazumasa, Kim Yangsu, Igarashi Susumu, Kaneko Kimihiko, Takahashi Toshiyuki, Irioka Takashi, Yokota Takanori. A Variety of Myelin Oligodendrocyte Glycoprotein Antibody Positive Central Nervous System Disorders. 第60回日本神経学会学術大会 2019.05.25

  30. 高橋 直, 宮本 翔平, 三條 伸夫, 横田 隆徳. Width of the third ventricle is high-sensitive marker for chronic progressive neuro-Behcet's disease. 第60回日本神経学会学術大会 2019.05.25

  31. Sanjo Nobuo, Shishido-hara Yukiko, Nose Yurie, Yokota Takanori. Progressive multifocal leukoencephalopathy in the era of disease-modifying therapies　A controlled inflammation and a regulatory immune system are associated with better prognosis of PML. 第60回日本神経学会学術大会 2019.05.25

  32. Yokota Takanori. Oligonucleotide drug for treatment of ALS. 第６０回日本神経学会学術大会 2019.05.25

  33. Sunao Takahashi, Syouhei Miyamoto, Nobuo Sanjo, Takanori Yokota.. Width of the third ventricle is a high-sensitive biomarker for deep grey matter atrophy in chronic progressive type of neuro-Behçet’s disease. . 第60回日本神経学会学術大会 2019.05.25 大阪

  34. Kenta Kori, Nobuo Sanjo, Yohsuke Yagi, Takefumi Sato, Takanori Yokota. . Distinguishing Multiple Sclerosis and Primary CNS Lymphoma by quantifying micro RNA in cell-free CSF.. 第60回日本神経学会学術大会 2019.05.25 大阪

  35. Nobuo Sanjo, Yukiko Shishido-hara, Yurie Nose, Takanori Yokota.. A controlled inflammation and a regulatory immune system are associated with better prognosis of PML. . 第60回日本神経学会学術大会 2019.05.25 大阪

  36. Irioka Takashi, Motomura Masakatsu, Uchihara Toshiki, Shintaku Hiroshi, Ishikawa Kinya, Igarashi Susumu, Majima Takamasa, Takahashi Yuko K, Iwase Ryo, Otani Tai, Kitanosono Hiroko, Shiraishi Hirokazu, Tsuura Yukio, Yokota Takanori. Clinicopathological study of a patient with calcium channels antibody-associated cerebellar ataxia. 第60回日本神経学会学術大会 2019.05.24

  37. Kim Yangsu, Iwase Ryo, Otani Tai, Igarashi Susumu, Soga Kazumasa, Irioka Takashi, Yokota Takanori. Varicella-zoster virus encephalitis followed by herpes zoster in hemodialysis patients. 第60回日本神経学会学術大会 2019.05.24

  38. Hirata Kosei, Hattori Takaaki, Chen Qingmeng, Ohara Masahiro, Kina Satoko, Yokota Takanori. Striatal dopamine depletion correlates with variability of stride length in Parkinson's disease. 第60回日本神経学会学術大会 2019.05.24

  39. Ishiguro Taro, Yokota Takanori, Ishikawa Kinya, Nagai Yoshitaka, Petrucelli Leonard. Spt4 knockdown suppressed SCA31-linked expanded UGGAA repeat-induced toxicity in Drosophila. 第60回日本神経学会学術大会 2019.05.24

  40. Akaza Miho, Kawabata Shigenori, Watanabe Taishi, Hasegawa Yuki, Iida Shintaro, Sasaki Toru, Adachi Yoshiaki, Sekihara Kensuke, Kanouchi Tadashi, Sumi Yuki, Okawa Atsushi, Yokota Takanori. Diagnosis of C8 radiculopathy by magnetospinogram. 第60回日本神経学会学術大会 2019.05.23

  41. Yokote H,Amano R,Toru S,Hattori T,Nishida Y,Sanjo N,Yokota T. Brain atrophy is associated with higher serum amyloid A levels in patients with multiple sclerosis. 第60回日本神経学会学術大会 2019.05.23 大阪

  42. Igarashi S,Otani T,Soga K,Irioka T,Kuhara T,Ozai K,Yokota T. Peri-insular sign:An MRI finding on acute fulminant hyperammonemia caused by a urea cycle disorder. 第60回日本神経学会学術大会 2019.05.23 大阪

  43. Yoshioka K,Lei Mon S,Jia C,Yamada H,Asami Y,Tanaka K,Wenying P,Kuwahara H,Nishina K,Nagata T,Yokota T. A novel antisense oligonucleotide terapy by overhanging heteroduplex oligonucleotide targeting CNS. 第60回日本神経学会学術大会 2019.05.23 大阪

  44. New DNA/RNA heteroduplex oligonucleotide technology for regulating functions of lymphocytes in vivo. 第60回日本神経学会学術大会 2019.05.22 大阪

  45. Ishibashi S,Li F,Iwasawa E,Suzuki M,Ichinose K,Yokota T. Upregulation of lipoprotein receptors on brain in the early phase of ischemic stroke in mice. 第60回日本神経学会学術大会 2019.05.22 大阪

  46. Yagi Y, Iida S, Kanouchi T, Kusunoki S, Sobue G, Kaji R, Kuwabara S, Yokota T, Glovenin-I CIDP Study Group. Maintenance treatment with IVIg for CIDP can prevent disease progression. 60th Annual Meeting of the Japanese Society of Neurology 2019.05.22 Osaka

  47. Zeniya S,Kuwahara H,Daizo K,Watari A,Kondo M,Yoshida-Tanaka K,Kaburagi H,Asada K,Nagata T,Nagahama M,Yagi K,Yokota T.. BBB-crossing drug delivery system by modulating tight junction at brain microvascular endothelium. 第６０回日本神経学会学術大会 2019.05.22 大阪

  48. Takahashi YK,Nishida Y,Nose Y,Ishibashi S,Sanjo N,Kanai T,Uzawa A,Oda F,Ozawa Y,Kuwabara S,Yokota T. Calcineurin inhibitors can be safely reduced in most patients with well-controlled myasthenia gravis. American Academy of Neurology(AAN)71st Annual Meeting 2019.05.06 Philadelphia

  49. Hashimoto Satoka, Inaji Motoki, Nariai Tadashi, Kobayashi Daisuke, Sanjo Nobuo, Yokota Takanori, Ishii Kenji, Maehara Taketoshi. 高グレード星細胞腫とtumefactive multiple sclerosisを鑑別するための[11C]Methionine PETの有用性(Usefulness of [11C] Methionine PET in the Differentiation of Tumefactive Multiple Sclerosis from High Grade Astrocytoma). Neurologia medico-chirurgica 2019.05.01

  50. 八木洋輔,横田隆徳. Small RNA profiling of cerebrospinal fluid exosomes. 第6回JMACシンポジウム 2019.01.24 東京

  1. Ohara Masahiro, Hattori Takaaki, Ishibashi Satoru, Sanjo Nobuo, Yokota Takanori. 進行性核上性麻痺患者は特発性正常圧水頭症様のMRI所見を有する(Progressive supranuclear palsy has idiopathic normal pressure hydrocephalus like MRI features). 臨床神経学 2018.12.01

  2. Ichijo Masahiko, Ishibashi Satoru, Miki Kazunori, Sugita Yoichiro, Itaya Sakiko, Amino Takeshi, Kamata Tomoyuki, Yokota Takanori. 静脈内rt-PA投与下のMCA閉塞患者における出血性変化の予測因子(Predictors of Hemorrhagic Transformation in Patients with MCA occlusion Receiving intravenous rt-PA). 臨床神経学 2018.12.01

  3. Akaza Miho, Akaza Itaru, Kanouchi Tadashi, Sasano Tetsuo, Sumi Yuki, Yokota Takanori. 血糖値変動とNCSで評価した糖尿病性ニューロパチーとの関連性の検討(Study for association between glycemic variability and diabetic neuropathy assessed by NCS). 臨床神経学 2018.12.01

  4. Uehara Takuya, Choong Chi-Jing, Nakamori Masayuki, Nishiyama Kumiko, Hayakawa Hideki, Kasahara Yuuya, Baba Kousuke, Nagata Tetsuya, Yokota Takanori, Tsuda Hiroshi, Obika Satoshi, Mochizuki Hideki. α-synucleinを標的とする新たなアンチセンスオリゴヌクレオチドはパーキンソンモデルマウスの運動機能を改善する(A new antisense oligos targeting alpha-synuclein improves motor function in Parkinson's model mouse). 臨床神経学 2018.12.01

  5. Sanjo Nobuo, Shishido-Hara Yukiko, Nose Yurie, Ono Daisuke, Sekijima Yoshiki, Yokota Takanori. 中枢神経系の炎症性JCウイルス感染時におけるPD-1の保護作用(Protective effect of PD-1 during inflammatory JC virus infection of the central nervous system). 臨床神経学 2018.12.01

  6. Shintaku Hiroshi, Yamaguchi Mari, Toru Syuuta, Kitagawa Masanobu, Hirokawa Katsuiku, Uchihara Toshiki, Yokota Takanori. 2D画像からの3D表面再構成　ヒト剖検脳への適用(3-dimensional surface reconstruction from 2-dimensional images. Application to human autopsied brain). 臨床神経学 2018.12.01

  7. Ishibashi Satoru, Iwasawa Eri, Suzuki Motohiro, Li Fuying, Ichijo Masahiko, Miki Kazunori, Yokota Takanori. S1P1活性化は軟髄膜の側副路発達を増強して脳卒中後のアウトカムを改善する(S1P1 activation enhances leptomeningeal collateral development and improves outcome after stroke). 臨床神経学 2018.12.01

  8. Mon Su Su Lei, Yoshioka Kotaro, Kunieda Taiki, Asami Yutaro, Tanaka Kie, Piao Wenying, Kuwahara Hiroya, Nishina Kazutaka, Nagata Tetsuya, Yokota Takanori. アンチセンスオリゴヌクレオチド二本鎖の新しい構造は脳室内経路を介した効果を改善する(A novel structure of duplex antisense oligonucleotides improves potency via intraventricular route). 臨床神経学 2018.12.01

  9. Yoshioka Kotaro, Kunieda Taiki, Asami Yutaro, Guo Huija, Enomoto Seiya, Miyata Haruka, Tanaka Kie, Piao Wenying, Kuwahara Hiroya, Nishina Kazutaka, Nagata Tetsuya, Yokota Takanori. 新しい種類の二本鎖オリゴヌクレオチドはin vivoにおいてmicroRNAサイレンシングの効力を増強する(A new class of double-stranded oligonucleotide enhances in vivo potency of microRNA silencing). 臨床神経学 2018.12.01

  10. Keisuke Inoue, Yoshiyuki Numasawa, Satoshi Sutou, Masaki Hakomori, Kazunori Toyoda, Hiroyuki Tomimitsu. The combination of Berg Balance Scale and Moss Attention Rating Scale for assessment of walking independence in acute ischemic stroke. The 20th Congress of the International Association of Rural Health and Medicine 2018.10.11 Tokyo

  11. Zen Kobayashi, Miho Yoshioka, Keisuke Inoue, Mayumi Watanabe, Kaori Kato, Kazunori Toyoda, Yoshiyuki Numasawa, Shoichiro Ishihara, Hiroyuki Tomimitsu, Shuzo Shintani. Serial changes in Trail Making Test score after mild ischemic stroke. The 20th Congress of the International Association of Rural Health and Medicine 2018.10.11 Tokyo

  12. Fumiko Furukawa,Keisuke Ishizawa,Taku Hatano,Chiaki Yanagisawa,Mikiya Suzuki,Yoji Goto,Kagari Mano,Yasushi Iwasaki,Katsuya Satoh,Tetsuyuki Kitamoto,Yoshikazu Nakamura,Masahito Yamada,Tadashi Tsukamoto,Hidehiro Mizusawa,Takanori Yokota,Nobuo Sanjo. Gerstmann-Sträussler-Sheinker syndrome with P105L mutation from prospective 19-years surveillance in Japan.. the Asian Pacific Prion Symposium 2018 2018.10.04 東京

  13. Takanori Yokota. Glycemic Control Boosts Glucosylated Nanocarrier Crossing the BBB into the Brain. The Oligo Meeting 2018 2018.10.03 Seatle

  14. Kotaro Yoshioka, Taiki Kunieda, Yutaro Asami, Kie Tanaka, Wenying Piao, Hiroya Kuwahara, Kazutaka Nishina, Shingo Ito, Tetsuya Nagata, Takanori Yokota. Overhanging heteroduplex oligonucleotides enable enhanced gene silencing by efficient delivery associated with transferrin. The 2018　Oligo Meeting, 14th Annual Meeting of the Oligonucleotide Therapeutics Society 2018.10.01 USA

  15. Satoshi Zeniya,Hiroya Kuwahara, Kaiichi Daizo, Akihiro Watari, Masuo Kondoh, Kie Yoshida-Tanaka,Hidetoshi Kaburagi, Ken Asada, Tetsuya Nagata, Masahiro Nagahama, Kiyohito Yagi, Takanori Yokota. Angubindin-1 for an efficient in vivo delivery of antisense oligonucleotide across the blood-brain barrier into brain. The 2018　Oligo Meeting, 14th Annual Meeting of the Oligonucleotide Therapeutics Society 2018.10.01 USA

  16. Tsuyoshi Hamaguchi, Kenji Sakai, Atsushi Kobayashi, Tetsuyuki Kitamoto, Ryusuke Ae, Yosikazu Nakamura, Nobuo Sanjo, Kimihito Arai, Mizuho Koide, Fumiaki Katada, Masafumi Harada, Hiroyuki Murai, Shigeo Murayama, Tadashi Tsukamoto, Hidehiro Mizusawa, Masahito Yamada. . Characterization of “sporadic CJD” with history of neurosurgery to identify iatrogenic cases. . European Creutzfeldt-Jakob Disease Surveillance Network (Euro CJD) 2018 2018.10.01 Roma, Italy

  17. Hiroya Kuwahara, Yasutaka Anraku, Kazunori Kataoka, Takanori Yokota. An efficient drug delivery system across the BBB by utilizing glycemic control. 第41回日本神経科学大会 2018.07.28 神戸

  18. Akiko Amano, Nobuo Sanjo, Makoto Nakakido, Kouhei Tsumoto, Etsuro Matsubara, Takanori Yokota. . Quantitative measurement of amyloid beta oligomer using dot blot assay. . 第41回日本神経科学大会 2018.07.26 神戸

  19. Nobuo Sanjo, Hiroya Kuwahara, Tetsuya Nagata, Yoichiro Nishida, Akiko Amano,Fumiko Furukawa, Kousei Hirata, Hiroyuki Maruoka, Makoto Nakakido, Tsumoto Kohei, Yasutaka Anraku, Kazunori Kataoka, Ichio Aoki, Etsuro Matsubara,Takami Tomiyama, Takanori Yokota. Morecular Imaging And Treatment of Alzheimer's Disease By Developing Amyloid-β oligomer Antibodies That Cross The Blood-Brain Barrier. AAIC 2018 2018.07.22 USA

  20. Akiko Amano, Nobuo Sanjo,Makoto Nakakido,Kouhei Tsumoto,Etsuro Matsubara,Fumiko Furukawa,Tetsuya Nagata,Yoichiro Nishida,Hiroya Kuwahara,kosei Hirata,Hiroyuki Maruoka,Takanori Yokota. Dot Blot Assay For Quantitative Measurement of Amyloid-Beta Oligomer. AAIC 2018 2018.07.22 USA

  21. Nobuo Sanjo, Hiroya Kuwahara, Tetsuya Nagata, Yoichiro Nishida, Akiko Amano, Fumiko Furukawa, Kousei Hirata, Hiroyuki Maruoka, Makoto Nakakido, Kohei Tsumoto, Yasutaka Anraku, Kazunori Kataoka, Ichio Aoki, Etsuro Matsubara, Takami Tomiyama, Takanori Yokota. . Molecular imaging and treatment of Alzheimer’s disease by developing amyloid-β oligomer antibodies that cross the blood-brain barrier. . Alzheimer's Association International Conference 2018 2018.07.22 Chicago, IL, USA

  22. Akiko Amano, Nobuo Sanjo, Makoto Nakakido, Kouhei Tsumoto, Etsuro Matsubara, Fumiko Furukawa, Tetsuya Nagata, Yoichirou Nishida, Hiroya Kuwahara, Kousei Hirata, Hiroyuki Maruoka, Takanori Yokota. . Dot blot assay for quantitative measurement of amyloid beta oligomer. . Alzheimer's Association International Conference 2018 2018.07.22 Chicago, IL, USA

  23. Mitsuteru Nakamura, Shuji Shinohara, Yasuhiro Omiya, Member, IEEE, Masakazu Higuchi, Naoki Hagiwara, Takeshi Takano, Shunji Mitsuyoshi, Nobuo Sanjo, Shinichi Tokuno. . Feasibility Study on Screening for Dementia using Voice Analysis. . International Engineering in Medicine and Biology Conference 2018 2018.07.17 Honolulu, HI, USA

  24. Takanori Yokota. Glycemic control enables glucosylated nanocarrier crossing the BBB into the brain. 日本核酸医薬学会　第4回年会 2018.07.11 福岡

  25. Su Su Lei Mon,Kotaro Yoshioka, Taiki Kunieda, Yutaro Asami, Wenying Piao, Kie Tanaka, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota . A novel structure of double-stranded heteroduplex oligonucleotides for intracerebroventricular application. 日本核酸医薬学会　第4回年会 2018.07.10 福岡

  26. Takanori Yokota,Hiroya Kuwahara, Takahiro Shimoura, Jindong Song,Kie Yoshida-Tanaka, Tadahaya Mizuno, Tatsuki Mochizuki, Kazutaka Nishina, Tetsuya Nagata,Hiroyuki Kusuhara,　. Modulation of blood-brain barrier function by a heteroduplex oligonucleotide in vivo. Keystone Symposia 2018.06.20 USA

  27. Takanori Yokota,Hiroya Kuwahara,Tetsuya Nagata,Yasutaka Anraku,Makoto Nakakido,Nobuo Sanjo,Kouhei Tsumoto,Kazunori Kataoka,Etsuro Matsubara. Development of blood-brain barrier-crossing amyloid-beta oligomer antibody.. 第59回 日本神経学会学術大会 2018.05.25 札幌

  28. Hiroya Kuwahara、Takanori Yokota. BBB-crossing delivery mechanism of glucosylated nanocarrier by glycemic control. 第59回日本神経学会学術大会 2018.05.25 札幌

  29. 横田隆徳. Development of blood-brain barrier-crossing amyloid-beta oligomer antibody. 第59回日本神経学会学術大会 2018.05.25 北海道

  30. Su Su Lei Mon,Kotaro Yoshioka, Taiki Kunieda, Yutaro Asami, Wenying Piao, Kie Tanaka, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. A novel structure of duplex antisense oligonucleotides improves potency via intraventricular route. 第59回日本神経学会学術大会 2018.05.24 札幌

  31. Tsuyoshi Hamaguchi, Kenji Sakai, Nobuo Sanjo, Ryusuke Ae, Yosikazu Nakamura, Tetsuyuki Kitamoto, Shigeo Murayama, Katsuya Satoh, Masafumi Harada, Tadashi Tsukamoto, Hidehiro Mizusawa, Masahito Yamada. . Proposing diagnostic criteria for MM2-cortical type sporadic Creutzfeldt-Jakob disease.. 第59回日本神経学会学術大会 2018.05.24 札幌

  32. Tetsuya Nagata、Takanori Yokota. Recent progress of DNA/RNA heteroduplex oligonucleotide. 第59回日本神経学会学術大会 2018.05.23 札幌

  33. Kotaro Yoshioka, Takanori Yokota. A new class of double-stranded oligonucleotide enhances in vivo potency of microRNA silencing. 第59回日本神経学会学術大会 2018.05.23 札幌

  34. Hiroya Kuwahara、Takanori Yokota. Glyccemic Control Boosts Glucosylated Nanocarrier Crossing the BBB into the Brain. AAN2018 2018.04.22

  1. Fumiko Furukawa,Ryusuke Ae,Yoshikazu Nakamura,Tsuyoshi Hamaguchi,Masahito Yamada,Tadashi Tsukamoto,Hidehiro Mizusawa,Takanori Yokota,Nobuo Sanjo. Analysis of clinical features of patients with lower limb muscle weakness in GSS with P102L mutation.. Asia Pacific Prion Symposium 2017.10.20 Melbourne,Australia

  2. Tadashi Tsukamoto,Nobuo Sanjo,Tsuyoshi Hamaguchi,Yoshikazu Nakamura,Tetsuyuki Kitamoto,Masahito Yamada,Hidehiro Mizusawa,and Prion Disease Surveillance Committee, Japan. Analysis of cases in which prion disease was denied by the Prion disease Surveillance Committee in Japan in 2016.. Asia Pacific Prion Symposium 2017.10.20 Melbourne,Australia

  3. Kotaro Yoshioka, Taiki Kunieda, Yutaro Asami, Yumiko Sujino, Kie Tanaka, Wenying Piao, Hiroya Kuwahara, Kazutaka Nishina, Tetsuya Nagata and Takanori Yokota. Dual overhanging-duplex oligonucleotide improved efficacy and safety in gene therapy for FAP. XX Ⅲ World Congress of Neurology 2017.09.20 Kyoto, JPN

  4. Akane Yamada,Yoshiyuki Numasawa,Takaaki Hattori,Kokoro Ozaki,Yoichiro Nishida,Satoru Ishibashi,Tadashi Kanouchi,Nobuo Sanjo,Takanori Yokota. Signal changes of skeletal muscle MRI in peripheral nerve disorders.. XXⅢ World Congress of Neurology 2017.09.16

  5. Ichinose K,Ishibashi S,Miyashita A,Sanjo N,Uchida K,Suzuki Y,Sekine M,Kobayashi D,Eishi Y,Yokota T. Clinicopathological features of neuromuscular sarcoidosis and its immunoreactivity profiles of P.acnes.. XXⅢ World Congress of Neurology 2017.09.16

  6. Hiroaki Yokote,Tomoyuki Kamata,Shuta Toru,Nobuo Sanjo,Takanori Yokota. Brain volume loss is present in Japanese patients with multiple sclerosis with no evidence of disease activity.. XXⅢ World Congress of Neurology 2017.09.16 Kyo,JPN

  7. Tsuyoshi Hamaguchi,Kenji Sakai,Atsushi Kobayashi,Tetsuyuki Kitamoto,Ryusuke Ae,Yoshikazu Nakamura,Nobuo Sanjo,Kimihito Arai,Mizuho Koide,Fumiaki Katada,Tadashi Tsukamoto,Hidehiro Mizusawa. Investigation of clinical and pathological features of "sporadic Creutzfeldt-Jakob disease" with history of neurosurgery identify iatrogenic cases.. XXⅢ World Congress of Neurology 2017.09.16 Kyoto,JPN

  8. Kenji Sakai,Tsuyoshi Hamaguchi,Nobuo Sanjo,Hiroyuki Murai,Yasushi Iwasaki,Tadanori Hamano,Mari Honma,Moeko Noguchi-Shinohara,Ichiro Nozaki,Yoshikazu Nakamura,Tetsuyuki Kitamoto,Hidehiro Mizusawa,Masahito Yamada. Diffusion-weighted MR images in dura mater graft-associated Creutzfeldt-Jakob disease.. XXⅢ World Congress of Neurology 2017.09.16 Kyoto,JPN

  9. Yoshiyuki Numasawa,Takaaki Hattori,Sumio Ishiai,Zen Kobayashi Tomoyuki Kamata,Minoru Kotera,Satoru Ishibashi,Nobuo Sanjo,Hidehiro Mizusawa,Takanori Yokota. Components of dipressive disorder due to Raphenuclei damage:subclass analysis of patients with brainstem infarction.. XXⅢ World Congress of Neurology 2017.09.16

  10. Hiroya Kuwahara, Jindong Song, Takahiro Shimoura, Kie Yoshida-Tanaka, Tadahaya Mizuno, Tatsuki Mochizuki, Kazutaka Nishina, Tetsuya Nagata, Hiroyuki Kusuhara, Takanori Yokota.. Modulation of blood-brain barrier function by heteroduplex oligonucleotide in vivo.. The 40th Annual Meeting of the Japan Neuroscience Society 2017.07.22 Chiba

  11. Fumiko furukawa,Nobuo Sanjo.Yoichiro Nishida,Etsuro Matsubara,Hiroki Akiba,Tsumoto Kohei,Takashi Saito,Takaomi Saido,Takanori Yokota. Analysis of Anti-amyloid β Oligomer Antibody Immunoreactivity in APP Knock-in Mice.. Alzheimer's Association International Conference 2017 2017.07.16 London,UK

  12. Masahito Yamada,Tsuyoshi Hamaguchi,Yu Taniguchi,Kenji Sakai,Tetsuyuki Kitamoto,Masaki Takao,Shigeo Murayama,Yasushi Iwasaki,Mari Yoshida,Hiroshi Shimizu,Akiyoshi Kakita,Hitoshi Takahashi,Hiroyoshi Suzuki,Hironobu Naiki,Nobuo Sanjo,Hidehiro Mizusawa. Possible human-to-human transmission of cerebral β-amyloidosis via cadaveric dura mater grafting.. Alzheimer's Association International Conference 2017 2017.07.16 London,UK

  13. Masahito Yamada,Tsuyoshi Hamaguchi,Kenji Sakai,Moeko Noguchi-Shinohara,Ichiro Nozaki,Yu Taniguchi,Atsushi Kobayash,Atsuko Takeuchi,Tetsuyuki Kitamoto,Yoshikazu Nakamura,Nobuo Sanjo,Tadashi Tsukamoto,Masaki Takao,Shigeo Murayama,Yasushi Iwasaki,Mari Yoshida,Hiroshi Shimuzu,Akiyoshi Kakita,Hitoshi Takahashi,Hiroyoshi Suzuki,Hironobu Naiki,Hidehiro Mizusawa. Iatrogenic Creutzfeldt-Jakob disease related to dura mater grafts.. Prion2017 2017.05.23 Edinburgh,UK

  14. Fumiko Furukawa,Tetsuya Kitamoto,Hidehiro Yosikazu Nakamura,Masahito Yamada,Tadashi Tsukamoto,Hidehiro Mizusawa,Takanori Yokota,Nobuo Sanjo. Clinicopathological features of Gerstmann-Sträussler-Scheinker syndrome with P105L mutation.. Prion2017 2017.05.23 Edinburgh,UK

  15. Tsuyoshi Hamaguchi,Kenji Sakai,Atsushi Kobayashi,Tetsuyuki Kitamoto,Ryusuke Ae,Yoshikazu Nakamura,Nobuo Sanjo,Tadashi Tsukamoto,Hidehiro Mizuwsawa,Masahito Yamada. Clinical and pathological characterization of "sporadic Creutzfeldt-Jakob disease" with histories of neurosurgery to identify iatrogenic cases. . Prion2017 2017.05.23 Edinburgh,UK

  1. Noriko Nakamura, Yasutaka Anraku, Hiroya Kuwahara, Takanori Yokota, Kazunori Kataoka. Development of innovative therapeutic nanomachines for intractable neurological diseases. 3rd COINS International Symposium 2016.12.15 Kawasaki

  2. Hiroya Kuwahara, Yasutaka Anraku, Kazunori Kataoka, Takanori Yokota. Investigation of delivery mechanism of BBB-crossing nanomachine. 3rd COINS International Symposium 2016.12.15 Kawasaki

  3. Yoshioka Kotaro, Kunieda Taiki, Tanaka Kie, Piao Wenying, Kuwahara Hiroya, Nishina Kazutaka, Nagata Tetsuya, Yokota Takanori. 新型の二本鎖構造はFAPに対するアンチセンスオリゴヌクレオチドの効能を改善させる(A new type of double-stranded structure improved potency of antisense oligonucleotide for FAP). 臨床神経学 2016.12.01

  4. Li Fuying, Ishibashi Satoru, Yoshioka Kotaro, Wada Takehiko, Ichijo Masahiko, Iwasawa Eri, Song Jindong, Zhang Yongquan, Yokota Takanori. ヘテロ二重鎖オリゴヌクレオチドはマウス局所脳虚血において遺伝子発現を低下させる(Heteroduplex oligonucleotide reduced gene expression in focal ischemic brain in mice). 臨床神経学 2016.12.01

  5. Nishina Kazutaka, Yoshioka Kotaro, Nishina Tomoko, Kuwahara Hiroya, Nagata Tetsuya, Yokota Takanori. DNA/RNAヘテロ二本鎖構造に基づく新規オリゴヌクレオチド(Novel oligonucleotide based on DNA/RNA heteroduplex structures). 臨床神経学 2016.12.01

  6. Takanori Yokota. DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing. 3rd International Conference on Biomaterials Science. 2016.11.30 Tokyo

  7. Hiroya Kuwahara, Takahiro Shimoura, Jindong Song, Kie Yoshida-Tanaka, Tadahaya Mizuno, Tatsuki Mochizuki, Kazutaka Nishina, Tetsuya Nagata, Hiroyuki Kusuhara, Takanori Yokota. Novel oligonucleotide to regulate the blood-brain barrier. 3rd International Conference on Biomaterials Science 2016.11.28 Tokyo

  8. Yohsuke Yagi, Takuya Ohkubo, Hideya Kawaji, Akira Machida, Haruka Miyata, Saori Goda, Sugata Roy, Yoshihide Hayashizaki, Harukazu Suzuki, Takanori Yokota. Small RNA profiling of cerebrospinal fluid exosomes using next-generation sequencing. American Society for Exosomes and Microvesicles 2016 2016.10.21 California

  9. Kotaro Yoshioka, Yumiko Sujino, Taiki Kunieda, Kie Tanaka, Wenying Piao, Hiroya Kuwahara, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. Intracellular mechanisms of microRNA inhibition by a new double-stranded structure for therapeutic oligonucleotide. 12th Annual Meeting of the Oligonucleotide Therapeutics Society 2016.09.27 Montreal

  10. Takanori Yokota. DNA/RNA heteroduplex oligonucleotide. 12th Annual Meeting of the Oligonucleotide Therapeutics Society 2016.09.27 Montreal

  11. Taiki Kunieda, Kotaro Yoshioka, Yumiko Sujino, Kie Tanaka, Wenying Piao, Hiroya Kuwahara, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. Pharmacokinetic study of double stranded antisense oligonucleotide: Hetero Chimera Duplex Oligonucleotide (HCDO). 12th Annual Meeting of the Oligonucleotide Therapeutics Society 2016.09.26 Montreal

  12. Hiroya Kuwahara, Takahiro Shimoura, Jindong Song, Kie Yoshida-Tanaka, Tadahaya Mizuno, Tatsuki Mochizuki, Masaki Ohyagi, Kazutaka Nishina, Tetsuya Nagata, Hiroyuki Kusuhara, Takanori Yokota. New platform technology to regulate the blood-brain barrier function in vivo. 19th International Symposium on Signal Transduction at the Blood-Brain Barriers 2016.09.15 Copenhagen

  13. Masahito Yamada,Tsuyoshi Hamaguchi,Yu Taniguchi,Kenji Sakai,Tetsuyuki Kitamoto,Masaki Takao,Shigeo Murayama,Yasushi Iwasaki,Mari Yoshida,Hiroshi Shimizu,Akiyoshi Kakita,Hitoshi Takahashi,Hiroyoshi Suzuki,Hironobu Naiki,Nobuo Sanjo,Hidehiro Mizusawa,. Possible iatrogenic transmissison of cerebral amyloid angiopathy and subpialAβ deposition via cadaveric dura mater grafting.. 5th International CAA conference 2016 2016.09.08 Boston,USA

  14. Takanori Yokota. Propagation of TDP-43 in ALS. Propagation in Neurodegenerative Disease Conference 2016 2016.08.11 Dublin

  15. Yoichiro Nishida, Daishi Yui, Tomoko Nishina, Kaoru Mogushi, Satoru Ishibashi, Itsuki Ajioka, Kinya Ishikawa, Hidehiro Mizusawa, Shigeo Murayama, Takanori Yokota. Enhanced Pla2g3 expression by oxidative stress decreases the IDE and exacerbates AD. Alzheimer's Association International Conference 2016 2016.07.26 Toronto

  16. Fumiko Furukawa, Nobuo Sanjo, Atsushi Kobayashi, Tsuyoshi Hamaguchi, Masahito Yamada, Tetsuyuki Kitamoto, Hidehiro Mizusawa, Takanori Yokota. Colocalization of Aβ42 with PrPSc-plaques in the brain of the Gerstmann-Sträussler-Scheinker disease with the P105L mutation. Alzheimer's Association International Conference 2016 2016.07.24 Toronto

  17. Yoko Ito,Nobuo Sanjo,Yukiko Matsumoto,Takanori Yokota. Optimal starting time of cholinesterase inhibitors for amnestic MCI.. Alzheimer's Association International Conference 2016 2016.07.14 Toronto,Canada

  18. Kazutaka Nishina, Kie Yoshida-Tanaka, Wenying Piao, Takanori Yokota. DNA/RNA heteroduplex oligonucleotide (HDO) for highly efficient gene silencing. The RNA society of Japan 18th annual meeting (The 21st annual meeting of the RNA society) 2016.06.30 Kyoto

  19. Fumika Sakaue, Eiji Yasuda, Tatsuhiko Sano, Taro Ishiguro, Tetsuya Nagata, Takanori Yokota. Chemically modified RNAs inhibit TDP-43 aggregation. The RNA society of Japan 18th annual meeting (The 21st annual meeting of the RNA society) 2016.06.29 Kyoto

  20. Kotaro Yoshioka, Yumiko Sujino, Taiki Kunieda, Kie Tanaka, Wenying Piao, Hiroya Kuwahara, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. A new mechanism of microRNA inhibition by a new type of duplex oligonucleotide. The RNA society of Japan 18th annual meeting (The 21st annual meeting of the RNA society) 2016.06.29 Kyoto

  21. Taiki Kunieda, Kotaro Yoshioka, Yumiko Sujino, Kie Tanaka, Wenying Piao, Hiroya Kuwahara, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. Development of antisense oligonucleotide with a new type of a double stranded structure. The RNA society of Japan 18th annual meeting (The 21st annual meeting of the RNA society) 2016.06.29 Kyoto

  22. Ogata H, Yamasaki R, Oka N, Kuwahara M, Suzuki H, Kusunoki S, Yagi Y, Matsushita T, Yokota T, Kira J-I. Valuable objective markers for predicting anti-neurofascin 155 antibody status among CIDP patients. The International Inflammatory Neuropathy Consortium 2016 2016.06.22 Glasgow

  23. Hiroshi Doi, Shigeru Koyano, Misako Kunii, Shunta Hashiguchi, Hitaru Kishida, Kenichi Tanaka, Masaaki Shiina, Kazuhiro Ogata, Fumiko Hirashima, Yukichi Inoue, Nozomu Sato, Kokoro Ozaki, Kiyobumi Ohta, Takanori Yokota, Hidehiro Mizusawa, Jun Mitsui, Shoji Tsuji, Naomichi Matsumoto, Kinya Ishikawa, Fumiaki Tanaka. The clinical and pathological features of autosomal-dominant SCA with CACNA1G mutation. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.21 Kobe

  24. Keisuke Abe, Mio Tajiri, Daishi Yui, Hiroki Sasaguri, Takuya Ohkubo, Takanori Yokota. A C-terminal fragment of TDP-43 in exosomes mediates propagation of ALS pathology. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.20 Kobe

  25. Masahiko Ichijo, Satoru Ishibashi, Kazunori Miki, Eri Iwasawa, Kyohei Fujita, Hiroaki Yokote, Takeshi Amino, Tomoyuki Kamata, Takanori Yokota. Significance of development and reversion of collaterals in outcome after intravenous thrombolysis. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.20 Kobe

  26. Toshiro Kanazawa, Yurie Nose, Yutaro Asami, Jin Nonami, Masahide Iijima, Hiroaki Tanaka, Takanori Yokota. Clinical features of patients with motor fluctuations before intravenous thrombolysis. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.20 Kobe

  27. Kazumasa Soga, Kinya Ishikawa, Tokuro Huruya, Hidehiro Mizusawa, Takanori Yokota. A clinical and neuropathological study on homozygous mutations with spinocerebellar ataxia type 6. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.20 Kobe

  28. Kazutaka Nishina, Kotaro Yoshioka, Tomoko Nishina, Hiroya Kuwahara, Tetsuya Nagata, Takanori Yokota. Novel oligonucleotide based on DNA/RNA heteroduplex structures. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.19 Kobe

  29. Kotaro Yoshioka, Taiki Kunieda, Kie Tanaka, Wenying Piao, Hiroya Kuwahara, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. A new type of double–stranded structure improved potency of antisense oligonucleotide for FAP. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.19 Kobe

  30. Eri Iwasawa, Satoru Ishibashi, Masahiko Ichijo, Fu Ying Li, Takanori Yokota. Upregulation and distribution of sphingosine-1-phosphate receptor 1 in acute ischemic stroke. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.19 Kobe

  31. Nozomu Sato, Kinya Ishikawa, Hidehiro Mizusawa, Takanori Yokota. Variations in the mutation for spinocerebellar ataxia type 31 require cautious genetic testing. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.19 Kobe

  32. Hiroya Kuwahara, Takahiro Shimoura, Jindong Song, Kie Yoshida-Tanaka, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. A novel platform technology to regulate the blood-brain barrier in vivo. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.19 Kobe

  33. Ogata H, Yamasaki R, Oka N, Kuwahara M, Suzuki H, Kusunoki S, Yagi Y, Yokota T, Matsushita T, Kira J-I. Useful laboratory markers for predicting anti-NF155 antibody status among CIDP patients. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.19 Kobe

  34. Yoichiro Nishida, Winkler Ethan, Sagare Abhay, De Vivo Darryl, Zlokovic Berislav. GLUT1 reductions at the BBB exacerbate Alzheimer disease vasculo-neuronal dysfunction. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.19 Kobe

  35. Jindong Song, Tetsuya Nagata, Wenying Piao, Kazutaka Nishina, Takuya Okubo, Keisuke Abe, Masato Hasegawa, Takanori Yokota. Inhibition of alpha-synuclein fibril assembly by antisense oligonucleotide in mice. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.18 Kobe

  36. Nobuo Sanjo, Hidehiro Mizusawa, Takanori Yokota. Various neurological manifestations of lymphoma. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.18 Kobe

  37. Fuying Li, Satoru Ishibashi, Kotaro Yoshioka, Takehiko Wada, Masahiko Ichijo, Eri Iwasawa, Jindong Song, Yongquan Zhang, Takanori Yokota. Heteroduplex oligonucleotide reduced gene expression in focal ischemic brain in mice. 57th Annual Meeting of the Japanese Society of Neurology 2016.05.18 Kobe

  38. Nobuo Sanjo. Various neurological manifestations of lymphoma. . 第57回日本神経学会学術大会 2016.05.18 神戸

  39. Fumiko Furukawa ,Nobuo Sanjo,Atsushi Kobayashi,Tsuyoshi Hamaguchi,Masahito Yamada,Tetsuyuki Kitamoto,Hidehiro Mizusawa. Differential association of amyloid-β with PrPSc pathology in each genetic prion disease.. Prion2016 2016.05.10 Tokyo,JPN

  40. Kenji Sakai,Tsuyoshi Hamaguchi,Nobuo Sanjo,Hiroyuki Murai,Moeko Noguchi-Shinohara,Ichiro Nozaki,Yoshikazu Nakamura,Tetsuyuki Kitamoto,Hidehiro Mizusawa,Masahito Yamada. Diffusion-weighted images in patients with dura mater garft-assosiated Creutzfeldt-Jakob disease.. Prion2016 2016.05.10 Tokyo,JPN

  41. Ryusuke Ae,Yoshikazu Nakamura, Ichiro Takumi,Nobuo Sanjo,Tetsuyuki Kitamoto,Hidehiro Mizusawa. Epidemiologic features of human prion diseases in Japan: a prospective 15-year surveillance study.. Prion2016 2016.05.10 Tokyo,JPN

  42. Tsuyoshi Hamagchi,Kenji Sakai,Tetsuyuki Kitamoto,Masaki Takao,Shigeo Murayama,Yasushi Iwasaki,Mari Yoshida,Hiroshi Shimizu,Akiyoshi Kakita,Hitoshi Takahashi,Hiroyoshi Suzuki,Hironobu Naiki,Nobuo Sanjo,Hidehiro Mizusawa,Masahito Yamada. Cerebral β-Amyloidsis in patients with dura mater graft-associated Creutzfeldt-Jakob disease.. Prion2016 2016.05.10 Tokyo,JPN

  43. Tadashi Tsukamoto,Ryusuke Ae,Yoshikazu Nakamura,Nobuo Sanjo,Tetsuyuki Kitamoto,Katsuya Satoh,Tsuyoshi Hamaguchi,Masahito Yamada,Hidehiro Mizusawa. Human Prion Diseases Surveillance and registration system in Japan.. Prion2016 2016.05.10 Tokyo,JPN

  44. Yuko Ishimura,Tadashi Tsukamoto,Kazuo Kuwata,Masahito Yamada,Katsumi Doh-ura,Yoshio Tsuboi,Katsuya Sato,Yoshikazu Nakamura,Nobuo Sanjo,Chieko Tamura,Hidehiro Mizusawa . The Japan Consortium of Prion diseases (JACOP) for patients' registration and clinical studies of Prion diseases in Japan. . Prion2016 2016.05.10 Tokyo,JPN

  45. Ichiro Takumi,Nobuhito Saito,Nobuo Sanjo,Shunsaku Takayanagi,Chieko Tamura,Tadashi Tsukamoto,Yoshiyuki Kuroiwa,Ryusuke Ae,Yoshikazu Nakamura,Tetsuyuki Kitamoto,Tsuyoshi Hamaguchi,Masahito Yamada,Hidehiro Mizusawa. CJD incidents in Japan.. Prion2016 2016.05.10 Tokyo,JPN

  46. Hiroya Kuwahara, Takahiro Shimoura, Jindong Song, Kie Yoshida-Tanaka, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. Hetero-duplex oligonucleotide to regulate the blood-brain barrier function in vivo. Oligonucleotide Therapeutics & Delivery 2016.04.04 Boston

  47. Takanori Yokota. DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing. Oligonucleotide Therapeutics & Delivery 2016.04.04 Boston

  48. Takanori Yokota. DNA/RNA heteroduplex oligonucleotide as a novel concept of therapeutic oligonucleotide. 8th AsiaTIDES Oligonucleotide and Peptide Therapeutics 2016.02.25 Kyoto

  49. Song J, Shimoura T, Kuwahara H, Yoshida-Tanaka K, Nishina K, Nagata T, Yokota T. New platform technology to regulate the blood-brain barrier function in vivo. 第8回CBIR+ONSA共催若手インスパイアシンポジウム 2016.02.20 Tokyo

  50. Asada K, Canestrari E, Fu X, Li Z, Makowski E, Wu YC, Mito JK, Kirsch DG, Baraban J, Paroo Z. Rescuing dicer Defects via Inhibition of an Anti-dicing Nuclease. The 2nd Annual Meeting of the Japan miRNA Society 2016.02.06 Nagoya

  1. Inagaki M, Uematsu R, Araki Y, Sakamoto S, Ishibashi S, Kashida H, Asanuma H, Yokota T, Wada T. Synthesis and antisense activities of new type of chimeric PRNA-DNA derivatives containing phosphoramidate linkage in PRNA-DNA junction. 2015 International Chemical Congress of Pacific Basin Societies 2015.12.17 Honolulu, HI

  2. Asai M, Uematsu R, Araki Y, Sakamoto S, Ishibashi S, Yokota T, Wada T. Tuning and optimization of on-off switching pH of PRNA for hypoxia specificity. 2015 International Chemical Congress of Pacific Basin Societies 2015.12.17 Honolulu, HI

  3. Yokota T. 2´-DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing. 2015 International Chemical Congress of Pacific Basin Societies 2015.12.15 Honolulu, HI

  4. 吉岡 耕太郎, 筋野 裕美子, 國枝 泰希, 下 剛典, 田中 規恵, 朴 文英, 桑原 宏哉, 仁科 一隆, 小比賀 聡, 横田 隆徳. Hetero-chimera-duplex-oligonucleotideによるエクソンスキッピング療法の開発(Development of exon-skipping therapy by hetero-chimera-duplex oligonucleotide). 臨床神経学 2015.12.01

  5. Kuwahara H, Shimoura T, Song J, Yoshida-Tanaka K, Nishina K, Nagata T, Yokota T. A new therapeutic oligonucleotide to regulate the blood-brain barrier in vivo. Barcelona BioMed Conference on “Blood Brain Barrier” 2015.11.02 Barcelona, Spain

  6. Hiroya Kuwahara, Takahiro Shimoura, Jingdong Song, Kie Yoshida-Tanaka, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. A new therapeutic oligonucleotide to regulate the blood-brain barrier in vivo. Barcelona BioMed Conferences on the Blood-Brain Barrier 2015.11.02 Barcelona

  7. Sanjo N, Tsukamoto T, Furukawa F, Higuma M, Hizume M, Nakamura Y, Satoh K, Kitamoto T, Yamada M, Yokota T, Mizusawa H. Human prion disease in Japan - a prospective surveillance from 1999. XXII World Congress of Neurology 2015.10.31 Santiago, Chile

  8. Ishiguro T, Sato N, Fujikake N, Ueyama M, Yokota T, Mizusawa H, Wada K, Nagai Y, Ishikawa K. The SCA31-linked UGGAAexp repeat forms RNA foci and is translated into aggregating pentapeptide-repeat proteins in the SCA31 patient brain and Drosophila model. 10th Brain Research Conference 2015.10.15 Chicago, IL

  9. Kuwahara H, Shimoura T, Song J, Yoshida-Tanaka K, Nishina K, Nagata T, Yokota T. A new therapeutic oligonucleotide to regulate the blood-brain barrier. 11th Annual Meeting of the Oligonucleotide Therapeutics Society 2015.10.14 Leiden, Netherlands

  10. Hiroya Kuwahara, Takahiro Shimoura, Jingdong Song, Kie Yoshida-Tanaka, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. A new therapeutic oligonucleotide to regulate the blood-brain barrier. 11th Annual Meeting of the Oligonucleotide Therapeutics Society 2015.10.14 Leiden

  11. Yoshioka K, Yoshida-Tanaka K, Piao W, Nishina T, Kuwahara H, Nishina K, Yokota T. Heteroduplex oligonucleotide (HDO): efficient drug delivery and processing mechanism. 11th Annual Meeting of the Oligonucleotide Therapeutics Society 2015.10.13 Leiden, Netherlands

  12. Kunieda T, Yoshioka K, Sujino Y, Yoshida-Tanaka K, Piao W, Kuwahara H, Nishina K, Nagata T, Yokota T. Enhancement of potency by gapmer type antisense oligonucleotides with Hetero-Chimera-Duplex-Oligonucleotide (HCDO). 11th Annual Meeting of the Oligonucleotide Therapeutics Society 2015.10.13 Leiden, Netherlands

  13. Nagata T, Ihara K, Kaburagi H, Nishina K, Piao W, Yoshida-Tanaka K, Guo H, Kuwahara H, Yoshioka K, Yokota T. The effect of DNA/RNA heteroduplex oligonucleotides in multiple organ systems. 11th Annual Meeting of the Oligonucleotide Therapeutics Society 2015.10.12 Leiden, Netherlands

  14. Hiroyuki Murai,Yoshikazu Nakamura,Tetsuyuki Kitamoto,Yoshio Tsuboi,Nobuo Sanjo,Masahito Yamada,Hidehiro Mizusawa,Jun-ichi Kira. Clinical and epidemiological survey of Gerstmann-Sträussler-Scheinker disease with codon 102 mutation in Japan.. XXII World Congress of Neurology 2015.09.30 Santiago,Chille

  15. Nobuo Sanjo,Tadashi Tsukamoto,Fumiko Furukwa,Maya Higuma,Masaki Hizume,Yoshikazu Nakamura,Katsuya Satoh,Tetsuyuki Kitamoto,Masahito Yamada,Takanori Yokota,Hidehiro Mizusawa. Human prion disease in Japan - a prospective surveillance from 1999 -. XXII World Congress of Neurology 2015.09.30 Santiago,Chile

  16. Furukawa F, Sanjo N, Kobayashi A, Hamaguchi T, Yamada M, Kitamoto T, Mizusawa H, Yokota T. Amyloid-β42 deposition in the brain of the Gerstmann-Sträussler-Scheinker disease with the P105L mutation. Asian Pacific Prion Symposium 2015 2015.09.04 Kanazawa, Japan

  17. Tsukamoto T, Sanjo N, Hamaguchi T, Nakamura Y, Kitamoto T, Yamada M, Mizusawa H. CJD with M232R: Its clinic-pathological features. Asian Pacific Prion Symposium 2015 2015.09.04 Kanazawa, Japan

  18. Sanjo N, Hamaguchi T, Tsukamoto T, Nakamura Y, Kitamoto T, Yamada M, Yokota T, Mizusawa H. Surveillance of prion disease in Japan. Asian Pacific Prion Symposium 2015 2015.09.04 Kanazawa, Japan

  19. Fumiko Furukawa,Nobuo Sanjo,Atsushi Kobayashi,Tsuyoshi Hamaguchi,Masahito Yamada,Tetsuyuki Kitamoto,Hidehiro Mizusawa. Amyloid-β42 deposition in the brain of Gerstmann-Sträussler-Scheinker disease with the P105L mutation.. Asian Pacific Prion Symposium 2015 2015.09.04 Kanazawa,JPN

  20. Tadashi Tsukamoto,Nobuo Sanjo,Tsuyoshi Hamaguchi,Yoshikazu Nakamura,Tetsuyuki Kitamoto,Masahito Yamada,Hidehiro Mizusawa,Prion Disease Surveillance Comittee (Japan). CJD with M232R : Its clinicopathological features. . Asian Pacific Prion Symposium 2015 2015.09.04 Kanazawa,JPN

  21. Nobuo Sanjo,Tsuyoshi Hamaguchi,Tadashi Tsukamoto,Yoshikazu Nakamura,Tetsuyuki Kitamoto,Masahito Yamada,Takanori Yokota,Hidehiro Mizusawa,Prion Disease Surveillance Comittee (Japan). Surveillance of prion disease in Japan. Asian Pacific Prion Symposium 2015 2015.09.04 Kanazawa,JPN

  22. Hiroya Kuwahara, Takahiro Shimoura, Jingdong Song, Kie Yoshida-Tanaka, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. A new platform technology to regulate the blood-brain barrier for molecular targeted therapy of multiple sclerosis. The Inaugural Asia-Pacific School of Neuroimmunology 2015.08.30 Tokyo

  23. Nobuo Sanjo,Satoko Kina,Yukiko Shishido-Hara,Yurie Nose,Satoru Ishibashi,Testuya Fukuda,Taketoshi Maehara,Yoshinobu Eishi,Hidehiro Mizusawa,Takanori Yokota. A Case of inflammatory progressive multifocal leukoencephalopathy with balanced CD8:CD4 T cell ratio.. 2nd International Conference on Progressive Multifocal Leukoencephalopathy(PML) 2015 2015.08.25 Mölndal,Sweden

  24. Ishiguro T, Fujikake N, Sato N, Ueyama M, Yokota T, Wada K, Mizusawa H, Nagai Y, Ishikawa K. Expanded UGGAA repeat RNA associated with SCA31 causes progressive neurodegeneration in Drosophila. The 38th Annual Meeting of the Japan Neuroscience Society, 2015.07.29 Kobe, Japan

  25. Higuma M, Sanjo N, Mitoma H, Yokota T. Relationship between attention and gait cycle in the patients with Alzheimer's disease. Alzheimer's Association International Conference 2015 2015.07.18 Washington, DC

  26. Maya Higuma,Nobuo Sanjo,Hiroshi Mitoma,Takanori Yokota. Relationship between attention and gait cycle in the patients with Alzheimer's disease.. Alzheimer's Association International Conference 2015 2015.07.18 Washington DC,USA

  27. Furukawa F, Sanjo N, Higuma M, Kitamoto T, Hizume M, Nakamura Y, Tsukamoto T, Murayama S, Koshi K, Matsukawa T, Tsuji S, Goto J, Yamada M, Mizusawa H, Yokota T. Clinical features in Gerstmann-Straussler-Scheinker syndrome with P105L mutation. Prion2015 2015.05.26 CO

  28. Fumiko Furukawa,Nobuo Sanjo,Maya Higuma,Tetsuyuki Kitamoto,Masaki Hizume,Yoshikazu Nakamura,Tadashi Tsukamoto,Shigeo Murayama,Kagari Koshi,Takashi Matsukawa,Shoji Tsuji,Jun Goto,Msahito Yamada,Hidehiro Mizusawa,Takanori Yokota. Clinical features in Gerstmann-Sträussler-Scheinker syndrome with P105L mutation.. Prion2015 2015.05.26 Fort Collins,USA

  29. Majima Takamasa,Nobuo Sanjo,Takanori Yokota. Cognitive Impairment correlates with cerebral atrophy especially with white matter atrophy in Japanese MS patients. . MS medical symposium 2015.05.23 Niigata

  30. Hiroaki Yokote,Tomoyuki Kamata,Nobuo Sanjo,Takanori Yokota. Serum retinol levels are associated with brain volume loss in patients with multiple sclerosis.. MS medical symposium 2015.05.23 Niigata

  31. Hiroya Kuwahara, Kazutaka Nishina, Wenying Piao, Takanori Yokota. Development of nanomachine that delivers therapeutic oligonucleotide across the blood-brain barrier into brain. 1st COINS International Symposium 2015.02.27 Tokyo

  1. Kotaro Yoshioka, Yumiko Sujino, Kie Tanaka, Wenying Piao, Tomoko Nishina, Hiroya Kuwahara, Kazutaka Nishina, Takanori Yokota.. Hetero-chimera-duplex oligonucleotide (HCDO): A new class of oligonucleotide for enhancement of efficacy of microRNA inhibitor.. 10th annual meeting of the Oligonucleotide Therapeutics Society. 2014.10.12 San Diego.

  2. Hiroya Kuwahara, Takanori Yokota. Development of BBB-targeting nucleic acid medicine. The 37th Annual Meeting of the Japan Neuroscience Society 2014.09.13 Yokohama

  3. Keisuke Abe, Taku Namatame, Mio Tajiri, Daishi Yui, Takuya Ohkubo, Takanori Yokota. Selective uptake of C-terminal fragments of TDP-43 into exosome. The 37th Annual Meeting of Japan Neuroscience Society 2014.09.12 Yokohama,Japan

  4. Takanori Yokota. Oligonucleotide Gene Therapy for ALS. The 37th Annual Meeting of the Japan Neuroscience Society 2014.09.12 Yokohama

  5. Takuya Ohkubo, Akira Machida, Kaoru Mogushi, Hidenori Matsuo, Atsushi Tsunoda, Taketoshi Maehara, Yuichi Noto, Toshio Shimizu, Satoshi Kuwabara, Takashi Kanda, Nobuyoshi Kosaka, Takahiro Ochiya, Takanori Yokota. Profiling of miRNAs in cerebrospinal fluid form patients with multifocal motor neuropathy and amyotrophic lateral sclerosis. The 37th Annual Meeting of the Japan Neuroscience Society 2014.09.11 Yokohama

  6. Kotaro Yoshioka, Kie Tanaka, Wenying Piao, Kazutaka Nishina, Takanori Yokota.. A new class of oligonucleotide drug; DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing.. 6th TMDU International Summer Program (ISP2014). 2014.08.26

  7. Maya Higuma, Nobuo Sanjo, Yoko Ito, Fumiko Furukawa, Hiroshi Mitoma, Hidehiro Mizusawa. Relationship between gait and cognitive function in patients with Alzheimer’s disease. Alzheimer’s Association International Conference 2014 2014.07.13

  8. Nobuo Sanjo, Maya Higuma, Masaki Hizume, Fumiko Furukawa, Yosikazu Nakamura, Tetsuyuki Kitamoto, Tsuyoshi Hamaguchi, Fumio Moriwaka, Masashi Aoki, Fumiaki Tanaka, Masatoyo Nishizawa, Masatoshi Takeda, Takashi Inuzuka, Koji Abe, Kota Sato, Hiroyuki Murai, Shigeo Murayama, Katsuya Satoh, Masafumi Harada, Naoto Uyama, Koji Fujita, Nobuhito Saito, Ichiro Takumi, Tadashi Tsukamoto, Masahito Yamada, Hidehiro Mizusawa.. Human prion diseases in Japan: a prospective surveillance from 1999. . Asian Pacific Prion Symposium 2014 2014.07.06

  9. Kazuo Kuwata, Hidehiro Mizusawa, Nobuo Sanjo, Noriyuki Nishida, Takayuki Fuse, Fumiko Ono, Hiroaki Shibata, Mayuko Fukuoka, Yoko Matsusaki. . Toward the First in Human Clinical Trial of a Medical Chaperone for Prion Diseases. . Asian Pacific Prion Symposium 2014 2014.07.06

  10. Fumiko Furukawa, Nobuo Sanjo, Atsushi Kobayashi, Atsushi Shiraishi, Masahito Yamada, Tetsuyuki Kitamoto, Yoshinobu Eishi, Hidehiro Mizusawa. . Involvement of the dorsal root ganglion in GSS with P105L mutation. . Asian Pacific Prion Symposium 2014 2014.07.06

  11. Kenji Sakai, Tsuyoshi Hamaguchi, Moeko Noguchi-Shinohara, Ichiro Nozaki, Ichiro Takumi, Nobuo Sanjo, Yosikazu Nakamura, Tetsuyuki Kitamoto, Nobuhito Saito, Hidehiro Mizusawa, Masahito Yamada. . Graft-related disease progression in dura mater graft-associated Creutzfeldt–Jakob disease: a cross-sectional study. . Asian Pacific Prion Symposium 2014 2014.07.06

  12. Tsuyoshi Hamaguchi, Kenji Sakai, Ichiro Nozaki, Moeko Noguchi-Shinohara, Nobuo Sanjo, Yosikazu Nakamura, Tetsuyuki Kitamoto, Shigeo Murayama, Katsuya Satoh, Masafumi Harada, Hidehiro Mizusawa, Masahito Yamada. . Clinical features of MM2 type sporadic Creutzfeldt-Jakob disease. . Asian Pacific Prion Symposium 2014 2014.07.06

  13. Nobuo Sanjo, Maya Higuma, Masaki Hizume, Fumiko Furukawa, Yosikazu Nakamura, Tetsuyuki Kitamoto, Masahito Yamada, Kenji Sakai, Ichiro Nozaki, Moeko Noguchi-Shinohara, Tsuyoshi Hamaguchi, Fumio Moriwaka, Masashi Aoki, Fumiaki Tanaka, Masatoyo Nishizawa, Masatoshi Takeda, Takashi Inuzuka, Koji Abe, Hiroyuki Murai, Shigeo Murayama, Masaki Takao, Katsuya Satoh, Masafumi Harada, Nobuhito Saito, Ichirou Takumi, Hidehiro Mizusawa.. Human prion diseases in Japan: a prospective surveillance from 1999. . Prion 2014 2014.05.27

  14. Fumiko Furukawa, Nobuo Sanjo, Atsushi Kobayashi, Tetsuyuki Kitamoto, Atsushi Shiraishi, Kinya Ishikawa, Haruhisa Honda, Masahito Yamada, Hidehiro Mizusawa. . Clinical features of Gerstmann-Sträussler-Scheinker syndrome with a P105L mutation and a valine-encoding polymorphic codon 129 in the prion protein gene.. Prion 2014 2014.05.27

  15. Masaki Hizume, Nobuo Sanjo, Katsuya Satoh, Tsuyoshi Hamaguchi, Masahito Yamada, Yasushi Iwasaki, Atsushi Kobayashi, Tetsuyuki Kitamoto, Hidehiro Mizusawa.. Immunohistochemical and neuropathological analyses of the prion protein in genetic Creutzfeldt-Jakob disease with V180I mutation.. Prion 2014 2014.05.27

  16. Sekiguchi T, Kanouchi T, Shibuya K, Noto YI, Yagi Y, Inaba A, Abe K, Misawa S, Orimo S, Kobayashi T, Kamata T, Nakagawa M, Kuwabara S, Mizusawa H, Yokota T. Spreading of amyotrophic lateral sclerosis lesions -multifocal hits & local propagation?. 30th international congress of clinical neurophysiology of the IFCN 2014.03.21 Berlin

  1. 吉岡 耕太郎, 渡邉 耕介, 日詰 正樹, 金澤 俊郎, 石橋 哲, 田中 宏明, 横田 隆徳, 水澤 英洋. 虚血性脳卒中患者における発作性心房細動に関する簡易スコア(A Simple Score For Paroxysmal Atrial Fibirillation in Ischemic Stroke Patients). 臨床神経学 2013.12.01

  2. Nobuo SANJO,Maya Higuma,Masaki HIDUME,Yoshikazu NAKAMURA,Tetsuyuki KITAMOTO,Masahito YAMADA,Kenji SAKAI,Ichiro NOZAKI,Moeko NOGUCHI-SHINOHARA,Tsuyoshi HAMGUCHI,Fumio MORIWAKA,Masashi AOKI,Yoshiyuki KUROIWA,Shigeru KAYANO,Masatoyo NISHIZAWA,Akio YOKOSEKI,Masatoshi TAKEDA,Kenji YOSHIYAMA,Takashi INUZUKA,Yuichi HAYASHI,Koji ABE,Hiroyuki MURAI,Shigeo MURAYAMA,Masaki TAKAO,Katsuya SATOH,Masafumi HARADA,Nobuhito SAITO,Ichirou TAKUMI,Hidehiro MIZUSAWA. Human prion disease in Japan: a prospective surveillance from 1999.. XXI World Congress of Neurology 2013.09.21 Vienna,Austria

  3. Tsuyoshi Hamaguchi,Kenji Sakai,Moeko Noguchi-Shinohara,Ichiro Nozaki,Ichiro Takumi,Nobuo Sanjo,Yoshikazu Nakamura,Tetsuya Kitamoto,Nobuhito Saitou,Hidehiro Mizusawa,Masahito Yamada. Comparison of dura mater graft-associated Creutzfeldt-Jakob disease between Japan and other countries.. Asian Pacific Prion Symposium 2013 2013.07.21 Nagasaki,JPN

  4. Fumiko Furukawa,Satoru Ishibashi,Nobuo Sanjo,Takashi Kurashige,Masayasu Matsumoto,Hidehiro Mizusawa. Serial magnetic resonance imaging changes in a patient in the early stages of sporadic Creutzfeldt-Jacob disease with valine homozygosity at codon 129 of PRNP.. Asian Pacific Prion Symposium 2013 2013.07.21 Nagasaki,JPN

  5. Masaki HIZUME,Nobuo SANJO,Yoshikazu NAKAMURA,Tetsuyuki KITAMOTO,Masahito YAMADA,Tsuyoshi HAMAGUCHI,Fumio MORIWAKA,Masashi AOKI,Yoshiyuki KUROIWA,Fumiaki TANAKA,Masatoyo NISHIZAWA,Masatoshi TAKEDA,Takashi INUZUKA,Koji ABE,Hiroyuki MURAI,Shigeo MURAYAMA,Katsuya SATOH,Masafumi HARADA,Nobuhito SAITO,Ichirou TAKUMI,Hidehiro Mizusawa. Human prion disease in Japan: a prospective surveillance from 1999.. Asian Pacific Prion Symposium 2013 2013.07.21 Nagasaki,JPN

  6. Maya Higuma,Nobuo Sanjo,Hiroshi Mitoma,Yoko Ito,Takumi Hori,Hidehiro Mizusawa. Quantitative Analysis of gait disorders in patient with Alzheimer's disease by using a portable gait rhythmograph.. Alzheimer's Association International Conference 2013 2013.07.13 Boston,USA

  7. Takumi Hori,Nobuo Sanjo,Hidehiro Mizusawa. Visual Reproduction on the Wechsler Memory Scale-Revised as a predictor of Alzheimer's disease in Japanese patients with mild cognitive impairments.. Alzheimer's Association International Conference 2013 2013.07.13 Boston,USA

  8. Hiroya Kuwahara, Kazutaka Nishina, Kie Yoshida-Tanaka, Tomoko Nishina, Wenying Piao, Hidehiro Mizusawa, Takanori Yokota. Efficient in vivo delivery of siRNA into brain capillary endothelial cells along with endogenous lipoprotein. 10th International Conference on Cerebral Vascular Biology 2013.06.19 Montreal

  9. Yohsuke Yagi, Hiroaki Yokote, Takeshi Amino, Tomoyuki Kamata. A Case of Unilateral White Matter Lesion: Widening of Virchow-robin Spaces. 11th International Conference on Alzheimer’s and Parkinson’s Diseases 2013.03.09 Florence

  10. Tomoyuki Kamata, Yohsuke Yagi. Clinical and Radiological Study of Patients with Hemichorea. 11th International Conference on Alzheimer’s and Parkinson’s Diseases 2013.03.09 Florence

  1. Hiroya Kuwahara, Hiroshi Fujita, Ken Matsumura, Mutsufusa Watanabe, Junji Tomiyama, Hiroto Fujigasaki. Cerebrovascular disorders in myeloproliferative neoplasms with the JAK2 V617F mutation. The 2nd International Congress on Neurology and Epidemiology 2012.11.08 Nice

  2. Temuqina,Nobuo Sanjo,Takumi Hori,Paul E. Fraser,Hidehiro Mizusawa. Pattern of Amyloid β Production by Mouse Embryonic Fibroblasts Overexpressing PSEN1 with 1143T Mutation.. Alzheimer's Association International Conference 2012 2012.07.14 Vancouver,Canada

  3. Tomoyuki Kamata, Yohsuke Yagi, Hiroaki Yokote, Takeshi Amino, Yukiko Watanabe, Yuriko Okabe. Finger Puppet Sign as Unique Clinical Presentation of Alzheimer's Dementia. 13th Asian Oceanian Congress of Neurology 2012.06.05 Melbourne

  4. Nobuo Sanjo,Maya Ohara,Katsuya Satoh,Tsuyoshi Hamaguchi,Yoshikazu Nakamura,Tetsuyuki Kitamoto,Masahito Yamada,Hidehiro Mizusawa. Cerebrospinal fluid findings in genetic prion disease in Japan and their association with clinical features.. Prion 2012 2012.05.09 Amsterdam,Netherland

  5. Kenji Sakai,Tsuyoshi Hamaguchi,Moeko Noguchi-Shinohara,Ichiro Nozaki,Takeshi Sato,Ichiro Takumi,Nobuo Sanjo,Yoshikazu Nakamura,Tetsuyuki Kitamoto,Nobuhito Saito,Hidehiro Mizusawa. Prion protein propagation in dura mater graft-associated Creutzfeldt-Jakob disease.. Prion 2012 2012.05.09 Amsterdam,Netherland

  1. Nobuo Sanjo,Temichina,Haifeng Jin,Toshiki Uchihara,Kazuhiko Watabe,Takumi Hori,Peter St. George-Hyslop,Paul E. Fraser,Hidehiro Mizusawa. Presenilin-1 holoprotein is an interacting partner of sarco endoplasmic reticulum calcium-ATPase and confers resistance to endoplasmic reticulum stress.. The 13th International ATPase Conference,Asilomer Conference Grounds,Pacific Grove 2011.09.27 California,USA

  2. Temuqina,Nobuo Sanjo,Takumi Hori,Paul E. Fraser,Hidehiro Mizusawa. An effect of 1143T PSEN1 Mutation on the Generation of Amyloid β in Culture Cells.. Alzheimer's Association International Conference 2011 2011.07.16 Paris,France

  3. Yamada M,Sanjo N,Murayama S,Takeda M,Kuzuhara S,Abe K,Noguchi-Shinohara M,Sakai K,Nozaki I,Mizusawa H,Hamaguchi T,Sadakane A,Nakamura Y,Sato T,Kitamoto T,Moriwaka F,Shiga Y,Kuroiwa Y,Nishizawa M,Inuzuka T,Kuroda Ｓ,Murai H,Tateishi J,Takumi I,Shirabe S,Harada M. Human prion disease in Japan: Analysis of 1552 Patients in a prospective 11-year surveillance.. Alzheimer's Association International Conference 2011 2011.07.16 Paris,France

  4. Maya Higuma,Nobuo Sanjo,Katsuya Satoh,Yusei Shiga,Kenji Sakai,Yoshikazu Nakamura,Tetsuyuki Kitamoto,Susumu Shirabe,Masaki Hizume,Shigeo Murayama,Masahito Yamada,Jun Tateishi,Hidehiro Mizusawa. Analysis of the clinical features of and biological markers in the cerebrospinal fluid in genetic prion disease in Japan.. Asian Pacific Prion Symposium 2011 2011.07.10 Karuizawa,JPN

  1. Maya Ohara,Nobuo Sanjo,Ichiro Nozaki,Tsuyoshi Hamaguchi,Masaki Hizume, Yoshikazu Nakamura,Tetsuyuki Kitamoto, Yusei Shiga,Katsuya Satoh,Takeshi Satoh,Susumu Shirabe,Masahito Yamada,Jun Tateishi,Hidehiro Mizusawa,. Genetic Prion disease in Japan, An analysis based on the Japanese CJD Surveillance, 1999-2009.. Prion 2010 2010.09.08 Salzburg,Austoria

  2. Kenji Sakai,Ichiro Nozaki,Tsuyoshi Hamaguchi,Moeko Noguchi-Shinohara,Yoshikazu Nakamura,Takeshi Sato,Tetsuyuki Kitamoto,Hidehiro Mizusawa,Nobuo Sanjo,Fumio Moriwaka,Yusei Shiga,Yoshiyuki Kuroiwa,Masatoyo Nishizawa,Takashi Inuzuka,Masatoshi Takeda,Koji Abe,Hiroyuki Murai,Shigeo Murayama,Jun Tateishi,Susumu Shirabe,Ichiro Takumi,Masafumi Harada,Masahito Yamada. Human prion diseases in Japan.. Prion 2010 2010.09.08 Salzburg,Austoria

  3. Sakai K,Nozaki I,Hamaguchi T,Noguchi-Shinohara M,Nakamura Y,Sato T,Kitamoto T,Mizusawa H,Sanojo N,Moriwaka F,Shiga Y,Kuroiwa Y,Nishizawa M,Inuzuka T,Takeda M,Abe K,Murai H,Murayama S,Tateishi J,Shirabe S,Takumi I,Harada M,Yamada M. Human prion diseases in Japan: a prospective surveillance from 1999.. Asia Oceania Symposium on Prion Disease 2010 2010.07.24 Sapporo,JPN

  4. Takumi Hori, Nobuo Sanjo,Mutsufusa Watanabe,Hiromi Utashiro,Hidehiro Mizusawa. Usefulness of Logical Memory Ⅱ of WMS-R for memory clinic outpatients.. International Conference in Alzheimer's Disease 2010 2010.07.10 Honolulu,USA

  5. Nobuo Sanjo,Haifeng Jin,Toshiki Uchihara,Kazuhiko Watabe,Takumi Hori,Peter St.George-Hyslop,Paul E.Fraser,Hidehiro Mizusawa,. Presenilin-1 holoprotein is an interacting partner of SERCA and confers resistance to ER stress.. International Conference in Alzheimer's Disease 2010 2010.07.10 Honolulu,USA

  6. Satoh K,Mutsukura K,Atarashi R,Shirabe S,Matsui Y,Kishida H,Kuroiwa Y,Sanjo N,Mizusawa H,Nishida N. Brain MRI Activity and Serum Biochemical Markers for Evaluating Blood-Brain Barrier Function in CreutzFeldt-Jakob Disease.. Prion 2010 2010.07

  1. Takayoshi Kobayashi, Yohsuke Yagi, Akira Machida, Shuta Toru, Toshiki Uchihara. Sialidosis and Malignancy: The possible Relationship between the Abnormal Metabolism of Sialic Acid and Malignancy from a Family of Genetically Defined Sialidosis. 19th World Congress of Neurology 2009.10.30 Bangkok

  2. Sanjo N,Shiga Y,Sato T,Yuasa T,Nakamura Y,Kitamoto T,Yamada M,Mizusawa H. MRI evidence of early cerebellar involvement in dura mater graft-associated Creutzfeldt-Jakob disease.. Prion 2009 2009.09.23 Chalkidiki,Greece

  3. Sanjo N,Jin H,Uchihara T,Watanabe K,Mizusawa H. Protective effect of endogenous PS 1 holoprotein under ER stress condition.. The 12th International Conference on Alzheimer's Disease and Related Disorders 2009.07.12 Vienna,Austria

  1. Sanjo N,Takahashi K,Jin H,Watanabe M,Mizusawa H,. Serine422 phosphorylation of tau protein by oxidative stress via c-jun N-terminal kinase(JNK) activation.. The 11th International Conference on Alzheimer's Disease and Related Disorders 2008 Chicago,USA

  1. 三條伸夫,金海峰,渡辺睦房,水澤英洋,内原俊記. Quantitative Change of APH-1 and Presenilin in culture cells under various type of endoplasmic reticulum(ER) stress.. 第26回 日本認知症学会 2007.10.17 大阪

  2. 三條伸夫,高橋勝義,金海峰,渡邊睦房,水澤英洋. Tau protein phosphorylation by oxidative stress via c-jun N-terminal kinase (JNK) activation.. 第26回 日本認知症学会 2007.10.17 大阪

  3. Uchihara T,Aoki-Yoshino K,Charies D,Nakamura A,Sanjo N,Kuroiwa T,Tsuchiya K,Song SY,Hauw JJ. Non-astrocytic expression of apolipoprotein E in the brain.. 13th International Psychogeriatric Association 2007.10.17 Osaka

  4. Sanjo N,Jin H,Watanabe M,Mizusawa H,Uchihara T. Quantitative Change of APH-1 and Presenilin in culture cells under various type of endoplasmic reticulum(ER) stress.. International Psychogeriatric Association 25#Uth#UR Anniversary 2007 2007.10.14 Osaka,JPN

  5. Sanjo N,Takahashi K,Jin H,Watanabe M,Mizusawa H,. Tau protein phosphorylation by oxidative stress via c-jun N-terminal kinase (JNK) activation.. International Psychogeriatric Association 25#Uth#UR Anniversary 2007 2007.10.14 Osaka,JPN

  6. Katayama T,Sanjo N,Fraser P,St George-Hyslop P,Sato K. A screening for novel components of gamma-secretase complex using by in vivo crosslink method.. Neuro 2007 2007.09.10 Yokohama,JPN

  7. Shiraishi A,Hino T,Sanjo N,Ishibashi S,Machida A,Mizutani S,Shintani S,Mizusawa H,. Dual-plane diffusion weighted Imaging can improve the detection of diffusion restricted lesions in patients suspected storke with mokd severity-Axial and colonal DWI for acute stroke(ACORDAS) study.. International Stroke Conference 2007 2007.02.07 San Francisco,USA

  1. 三條伸夫,金海峰,水澤英洋,片山泰一,Peter St. George-Hyslop,Paul E Fraser. 内因性 Aph-1 の oligomer 形成に関して. 第47回 日本神経学会総会 2006.05.11 東京

  1. Sanjo N,Katayama T,Gu Y,Hasegawa H,Chen F,St.George-Hyslop P,Fraser P. APH-1 Intracellular Trafficking and Its Relationship with gamma-Secretase Components.. The 9th International Conference on Alzheimer's Disease and Related Disorders, 2004.07.17 Philadelphia,USA

  1. Sanjo N,Owada K,Michikawa M,Awaya A,Mizusawa H. Effect of the neurotrophic pyrimidine compound MS-818 on cortical neurons.. Society for neuroscience 27th annual meeting 1997 New Orleans,USA

  1. Michikawa M,Sanjo N,Owada K,Muramatsu T,Muramatsu H,Cashman N R. Mitogen-Activated Protein (MAP) Kinase Phosphory by BDNF, NT-3,GDNF and MIDKINE in Motoneuron-Hybrid Cells.. 26th Annual meeting of Society of Neuroscience 1996 Washington DC,USA

  1. Michikawa M,Sanjo N,Yonemura I,Okano A,Shimizu Y,Kobayashi T,Hasekura H. The product of a longevity gene, JmA, has a neurotrophic effect on mouse cerebral cortical neurons in culture. . 24th Annual meeting of Society of Neuroscience 1994 Maiami,USA

  1. An autopsy case of coexisting spinal and bulbar muscular atrophy and multiple system atrophy.. 2024.05.17

  1. Keisuke Tanaka, Hikari Kanai, Hiroya Kuwahara, Kota Yoshifuji, keigo Okada, Yoshihiro Umezawa, Ayako Nogami, Toshikage Nagao, Chizuko Sakashita, Takehiko Mori, Masahide Yamamoto. Diffuse large B-cell lymphoma developed under the treatment of fingolimod. The Japanese Society for Lymphoreticular Tissue Reserch 2023.06.24

  1. Tojo Nakayama, Timothy Yu. Precision gene therapeutics for epileptic encephalopathy with antisense oligonucleotides. 2022.09.21

  2. Developing antisense oligonucleotide therapy for Dentatorubral-pallidoluysian atrophy (DRPLA). 2022.08.02

  3. Individualized clinical trials using oligonucleotides for Neurological rare disorders. 2022.08.02

  4. Individualized medicine with antisense oligonucleotides for rare neurological disorders. 2022.07.15

  5. Neurological adverse events following COVID-19 vaccination. 2022.05.21

  1. Haruka Miyata, Kotaro Yoshioka, Huijia Guo, Taiki Kunieda, Yutaro Asami, Kie Tanaka, Hiroya Kuwahara, Kazutaka Nishina, Tetsuya Nagata, Takanori Yokota. Efficient inhibition of microRNA by Hetero Duplex Oligonucleotide, HDO-antimiR.. 2017.07.12

  1. Distribution patterns of nerve conduction abnormality in CIDP. 2016.10.29

  2. Hiroya Kuwahara. Development of nucleic acid therapeutics to target the blood-brain barrier. The 22nd Symposium of Forum for Pharmaceutical Technology Innovation 2016.09.09 Tokyo

  3. Hiroya Kuwahara, Hiroto Fujigasaki, Tohru Tanizawa, Ken Matsumura, Mutsufusa Watanabe, Takanori Yokota, Toshiki Uchihara. An autopsy case of ALS with argyrophilic grain disease showing PSP-like cytopathology predominantly in cerebral cortex. The 57th Annual Meeting of the Japanese Society of Neuropathology 2016.06.02 Hirosaki

  4. Shintaku H, Kanouchi T, Yokota T. Pathophysiology of myoclonus in corticobasal syndrome. 57th annual meeting of the Japanese Society of Neurology 2016.05.21 Kobe

  5. Kanouchi T, Sekiguchi T, Yokota T. A pilot study on disease progression of ALS by quantitative analysis from a new viewpoint. 57th annual meeting of the Japanese Society of Neurology 2016.05.18 Kobe

  6. Amano E, Suzuki M, Ozaki K, Ishibashi S, Akaza M, Kanouchi T, Tohda S, Yokota T. A case of sensory dominant CIDP with conduction delay predominantly in the most distal segment (Japanese). 10th Tokyo Metropolitan Neuromuscular Electrodiagnosis Forum 2016.01.30 Tokyo

  1. Kuwahara H, Shimoura T, Song J, Yoshida-Tanaka K, Nishina K, Nagata T, Yokota T. Heteroduplex oligonucleotide to regulate the blood-brain barrier. 2nd COINS International Symposium 2015.11.24 Tokyo, Japan

  2. Iida S, Suzuki M, Sanjo N, Nishida Y, Kanouchi T, Yokota T. Predictive factors in nerve conduction study for remmision mentenance therapy in CIDP (Japanese). 45th Annual Meeting of The Japanese Society of Clinical Neurophysiology 2015.11.06 Osaka

  3. Kanouchi T, Sekiguchi T, Yokota T. Correlation between disease progression in the onset limb and symptom spread to the bulbar region in ALS (Japanese). 45th Annual Meeting of The Japanese Society of Clinical Neurophysiology 2015.11.06 Osaka

  4. Ono D, Kanouchi T, Sanjo N, Nishida Y, Ishikawa K, Yokota T. Somatosensory evoked potential in the patients with spinal cord atrophy in neuromyelitis optica and multiple sclerosis (Japanese). 45th Annual Meeting of The Japanese Society of Clinical Neurophysiology 2015.11.05 Osaka

  5. Narumi J, Kanouchi T, Akaza M, Aoyagi E, Yanagi N, Ohta N, Sumi Y, Yokota T, Hagihara M, Tohda S. Study for quality control in nerve conduction study (Japanese). 45th Annual Meeting of The Japanese Society of Clinical Neurophysiology 2015.11.05 Osaka

  6. Kanouchi T, Yokota T. Symposium 3. Electrophysiological aproach to the pathomechanism of lesion spread in ALS (Japanese). 45th Annual Meeting of The Japanese Society of Clinical Neurophysiology 2015.11.05 Osaka

  7. Yui D, Nishida Y, Nishina T, Ishibashi S, Ishikawa K, Yokota T, Mogushi K, Mizusawa H. Enhanced Pla2g3 expression by oxidative stress decreases IDE. 34th Japan Society for Dementia Research 2015.10.03 Aomori

  8. Kuwahara H, Shimoura T, Song J, Yoshida-Tanaka K, Nishina K, Nagata T, Yokota T. A new platform technology to regulate the blood-brain barrier for molecular targeted therapy of multiple sclerosis. Asia-Pacific School of Neuroimmunology 2015 2015.08.30 Tokyo, Japan

  9. Yokota T. DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing. The 21st Annual Meeting of Japan Society of Gene Therapy 2015.07.26 Osaka

  10. Kanouchi T, Sekiguchi T, Yokota T. Local progression at the onset lower limb and spread to the upper limb in ALS (Japanese). 56th Annual Meeting of The Japanese Society of Neurology 2015.05.23 Niigata

  11. Immunosuppressants and relapse rate of neuromyelitis optica in remission phase.. 2015.05.23

  12. Ishizu N, Hebisawa A, Yui D, Aikawa T, Mizusawa H, Yokota T, Watase K. Genetical studies on knockin mice carrying a PARK17 mutation. 56th Annual Meeting of the Japanese Society of Neurology 2015.05.22 Niigata

  13. Nishida Y, Yui D, Nishina T, Mogushi K, Ishibashi S, Ishikawa K, Mizusawa H, Yokota T. Pla2g3 is increased in Alzheimer disease cerebrum and causese reduction of IDE. 56th Annual Meeting of the Japanese Society of Neurology 2015.05.21 Niigata

  14. Ozaki K, Yui D, Wakabayashi T, Nishida Y, Iwatsubo T, Ishikawa K, Yokota T, Mizusawa H. Expression profile:mice cerebellum on high fat diet, oxidative stress, and aging. 56th Annual Meeting of the Japanese Society of Neurology 2015.05.21 Niigata

  15. Ohkubo T, Tajiri M, Abe K, Sekiguchi T, Uchihara T, Mizusawa H, Yokota T. Propagation of TDP-43 and pTDP-43 in non-human primate model of ALS. 56th Annual Meeting of the Japanese Society of Neurology 2015.05.21 Niigata

  16. Hattori T, Horovitz S, Lungu C, Ishiai S, Yokota T, Wassermann E, Hallett M. Neural Correlates of impaired Working Memory in Parkinson Disease. 56th Annual Meeting of the Japanese Society of Neurology 2015.05.21 Niigata

  17. Soga K, Sato N, Ozaki K, Higashi M, Hatsuya H, Takao M, Murayama S, Ishikawa K, Yokota T, Mizusawa H. Analysis of gene expressions in spinocerebellar ataxia (SCA) 31. 56th Annual Meeting of the Japanese Society of Neurology 2015.05.21 Niigata

  18. Abe K, Tajiri M, Yui D, Ohkubo T, Yokota T. Selective uptake of C-terminal fragments of TDP-43 into exosome. 56th Annual Meeting of the Japanese Society of Neurology 2015.05.21 Niigata

  19. Li F, Ishibashi S, Ichijo M, Yokota T. Oligonucleotide reduced gene expression in focal ischemic brain in mice. 56th Annual Meeting of the Japanese Society of Neurology 2015.05.21 Niigata

  20. Ota K, Ohkita M, Ishikawa K, Mizusawa H, Yokota T. Analysis of TPPP function in mitochondria using cultured HeLa cell. 56th Annual Meeting of the Japanese Society of Neurology 2015.05.21 Niigata

  21. Kuwahara H, Anraku Y, Fukusato Y, Nitta K, Mizoguchi A, Nishina K, Mizusawa H, Kataoka K, Yokota T. A new drug delivery system across the blood-brain barrier into brain. 56th Annual Meeting of the Japanese Society of Neurology 2015.05.20 Niigata

  22. Ishikawa K, Ishiguro T, Soga K, Higashi M, Sato N, Obayashi M, Niimi Y, Mizusawa H, Yokota T. Molecular pathogenesis of spinocerebellar ataxia type 31 (SCA31). 56th Annual Meeting of the Japanese Society of Neurology 2015.05.20 Niigata

  23. Ichijo M, Li F, Miki K, Ishibashi S, Mizusawa H, Yokota T. S1PR1 agonist exert a neuroprotective effect via enhancing collateral growth. 56th Annual Meeting of the Japanese Society of Neurology 2015.05.20 Niigata

  24. Ishibashi S, Ichijo M, Li F,Mizusawa H, Yokota T. S1PR1 expression and endothelial cell proliferation after focal ischemia in mice. 56th Annual Meeting of the Japanese Society of Neurology 2015.05.20 Niigata

  25. Ishiguro T, Fujikake N, Sato N, Ueyama M, Yokota T, Wada K, Mizusawa H, Nagai Y, Ishikawa K. SCA31-linked UGGAAexp RNA causes progressive neurodegeneration in Drosophila. 56th Annual Meeting of the Japanese Society of Neurology 2015.05.20 Niigata

  26. Yoshioka K, Sujino Y, Kunieda T, Shimo T, Tanaka K, Piao W, Kuwahara H, Nishina K, Obika S, YokotaT. Development of exon-skipping therapy by hetero-chimera-duplex oligonucleotide. 56th Annual Meeting of the Japanese Society of Neurology 2015.05.20 Niigata

  27. Nonami H, Kanouchi T, Ishibashi T, Yokota T. A case of multiple cranial nerve palsies with characteristic myoclonus-like involuntary movements of facial and cervical muscles (Japanese). 9th Tokyo metropolitan neuromuscular electrodiagnosis forum 2015.01.24 Tokyo

  1. Kanouchi T, Sekiguchi T, Yokota T. Correlation between local progression speed in the onset site and regional spread speed in amyotrophic lateral sclerosis. 44th Annual Meeting of the Japanese Society of Clinical Neurophysiology 2014.11.20 Fukuoka

  2. Hiroya Kuwahara, Toshiki Uchihara, Hiroto Fujigasaki, Toru Tanizawa, Ken Matsumura, Mutsufusa Watanabe, Hidehiro Mizusawa.. Distribution of phosphorylated TDP-43-positive oligodendroglial inclusions in the spinal cord of a rapidly progressive ALS patient.. The 55th Annual Meeting of the Japanese Society of Neuropathology 2014.06.06 Tokyo

  3. Hiroya Kuwahara, Kazutaka Nizhina, Kie Tanaka, Tomoko Nishina, Wening Piao, Hidehiro Mizusawa, Takanori Yokota. Drug delivery system targeting central nervous system by systemic administration. 55th Annual Meeting of the Japanese Society of Neurology 2014.05.24 Fukuoka

  4. Maya Ohara, Nobuo Sanjo, Yoko Ito, Hiroshi Mitoma, Hidehiro Mizusawa. Relationship between gait and cognitive function in patients with AD.. 55th Annual Meeting of the Japanese Society of Neurology 2014.05.21

  5. Kanouchi T, Sekiguchi T, Mizusawa H, Yokota T. Correlation between local progression speed in the onset site and regional spread speed in amyotrophic lateral sclerosis. 55th Annual Meeting of the Japanese Society of Neurology 2014.05.21 Fukuoka

  6. Sekiguchi T, Kanouchi T, Shibuya K, Noto Y, Yagi Y, Inaba A, Abe K, Misawa S, Orimo T, Kobayashi T, Kamata T, Nakagawa M, Kuwabara S, Mizusawa H, Yokota T . Correlation between nEMG findings in the muscles innervated by the lumbosacral segments and pyramidal tract signs in amyotrophic lateral sclerosis. 55th Annual Meeting of the Japanese Society of Neurology 2014.05.21 Fukuoka

To the head of this page.▲