分子神経科学

58  件  
※ 登録方法の違いにより重複して表示されている場合があります。

  1. Ai Minamidate, Michio Onizawa, Chikako Saito, Rie Hikichi, Tomoaki Mochimaru, Mai Murakami, Chiharu Sakuma, Takehito Asakawa, Yuichi Hiraoka, Shigeru Oshima, Takashi Nagaishi, Kiichiro Tsuchiya, Hiromasa Ohira, Ryuichi Okamoto, Mamoru Watanabe: A potent endocytosis inhibitor Ikarugamycin up-regulates TNF production. Biochem Biophys Rep. 2021.09; 27 101065. ( PubMed , DOI )

  2. Sally Eshiba, Takeshi Namiki, Yasuaki Mohri, Tomomi Aida, Naotaka Serizawa, Takakazu Shibata, Hironobu Morinaga, Daisuke Nanba, Yuichi Hiraoka, Kohichi Tanaka, Keiko Miura, Masaru Tanaka, Hisashi Uhara, Hiroo Yokozeki, Toshiaki Saida, Emi K Nishimura: Stem cell spreading dynamics intrinsically differentiate acral melanomas from nevi. Cell Rep. 2021.08; 36 (5): 109492. ( PubMed , DOI )

  3. Yuichi Hiraoka, Kaori Sugiyama, Daiki Nagaoka, Iku Tsutsui-Kimura, Kenji F Tanaka, Kohichi Tanaka: Mice with reduced glutamate transporter GLT1 expression exhibit behaviors related to attention-deficit/hyperactivity disorder. Biochem Biophys Res Commun. 2021.08; 567 161-165. ( PubMed , DOI )

  4. Mariko Onodera, Jan Meyer, Kota Furukawa, Yuichi Hiraoka, Tomomi Aida, Kohichi Tanaka, Kenji F Tanaka, Christine R Rose, Ko Matsui: Exacerbation of Epilepsy by Astrocyte Alkalization and Gap Junction Uncoupling. J Neurosci. 2021.03; 41 (10): 2106-2118. ( PubMed , DOI )

  5. Tadashi Shin, Yuichi Hiraoka, Tokiwa Yamasaki, Jamey D Marth, Josef M Penninger, Masami Kanai-Azuma, Kohichi Tanaka, Satoshi Kofuji, Hiroshi Nishina: MKK7 deficiency in mature neurons impairs parental behavior in mice. Genes Cells. 2021.01; 26 (1): 5-17. ( PubMed , DOI )

  1. Yoshifumi Abe, Norio Takata, Yuki Sakai, Hiro Taiyo Hamada, Yuichi Hiraoka, Tomomi Aida, Kohichi Tanaka, Denis Le Bihan, Kenji Doya, Kenji F Tanaka: Diffusion functional MRI reveals global brain network functional abnormalities driven by targeted local activity in a neuropsychiatric disease mouse model. Neuroimage. 2020.12; 223 117318. ( PubMed , DOI )

  2. Machi Horiai, Ayano Otsuka, Shizu Hidema, Yuichi Hiraoka, Ryotaro Hayashi, Shinji Miyazaki, Tamio Furuse, Hiroaki Mizukami, Ryoichi Teruyama, Masaru Tamura, Haruhiko Bito, Yuko Maejima, Kenju Shimomura, Katsuhiko Nishimori: Targeting oxytocin receptor (Oxtr)-expressing neurons in the lateral septum to restore social novelty in autism spectrum disorder mouse models. Sci Rep. 2020.12; 10 (1): 22173. ( PubMed , DOI )

  3. Tsuru H, Osaka M, Hiraoka Y, Yoshida M: HFD-induced hepatic lipid accumulation and inflammation are decreased in Factor D deficient mouse. Scientific reports. 2020.10; 10 (1): 17593. ( PubMed , DOI )

  4. Kensuke Ihara, Tetsuo Sasano, Yuichi Hiraoka, Marina Togo-Ohno, Yurie Soejima, Motoji Sawabe, Megumi Tsuchiya, Hidesato Ogawa, Tetsushi Furukawa, Hidehito Kuroyanagi: A missense mutation in the RSRSP stretch of Rbm20 causes dilated cardiomyopathy and atrial fibrillation in mice. Sci Rep. 2020.10; 10 (1): 17894. ( PubMed , DOI )

  5. Ihara Kensuke, Kuroyanagi Hidehito, Hiraoka Yuichi, Sasano Tetsuo, Furukawa Tetsushi: Cytoplasmic Expansion of RNA-Binding Motif Protein 20(Rbm20) is Critical for Development of Atrial Fibrillation in Mice(和訳中) 日本循環器学会学術集会抄録集. 2020.07; 84回 OE79-5. ( 医中誌 )

  6. Hirayama Takashi, Hiraoka Yuichi, Kitamura Eri, Miyazaki Shinji, Horie Kengo, Fukuda Tomokazu, Hidema Shizu, Koike Masato, Itakura Atsuo, Takeda Satoru, Nishimori Katsuhiko: Oxytocin induced labor causes region and sex-specific transient oligodendrocyte cell death in neonatal mouse brain(和訳中) The Journal of Obstetrics and Gynaecology Research. 2020.01; 46 (1): 66-78. ( 医中誌 )

  7. Yamada, T, Takechi M (Co-first), Yokoyama N, Hiraoka Y, Ishikubo H, Usami T, Furutera T, Taga Y, Hirate Y, Kanai-Azuma M, Yoda T, Ogawa-Goto K, Iseki S: Heterozygous mutation of the splicing factor Sf3b4 affects development of the axial skeleton and forebrain in mouse. Developmental Dynamics. 2020.01; ( PubMed , DOI )

  8. Mieradili Mulati, Yutaka Kobayashi, Akira Takahashi, Hoashi Numata, Masanori Saito, Yuichi Hiraoka, Hiroki Ochi, Shingo Sato, Yoichi Ezura, Masato Yuasa, Takashi Hirai, Toshitaka Yoshii, Atsushi Okawa, Hiroyuki Inose: The long noncoding RNA Crnde regulates osteoblast proliferation through the Wnt/β-catenin signaling pathway in mice. Bone. 2020.01; 130 115076. ( PubMed , DOI )

  1. Uchida Mizuki, Hida Hirotake, Mori Kentaro, Yoshimi Akira, Kitagaki Shinji, Yamada Kiyofumi, Hiraoka Yuichi, Aida Tomomi, Tanaka Kohichi, Ozaki Norio, Noda Yukihiro: Functional roles of the glial glutamate transporter (GLAST) in emotional and cognitive abnormalities of mice after repeated phencyclidine administration EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019.08; 29 (8): 914-924. ( PubMed , DOI )

  2. Yang-Yang Feng, Miao Tang, Mitsuhiro Suzuki, Chinthika Gunasekara, Yuki Anbe, Yuichi Hiraoka, Jun Liu, Helmut Grasberger, Mamoru Ohkita, Yasuo Matsumura, Ji-Yang Wang and Takeshi Tsubata: Essential Role of NADPH Oxidase–Dependent Production of Reactive Oxygen Species in Maintenance of Sustained B Cell Receptor Signaling and B Cell Proliferation J Immunol. 2019.03;

  1. Rie Murayama, Mariko Kimura-Asami, Marina Togo-Ohno, Yumiko Yamasaki-Kato, Taeko K Naruse, Takeshi Yamamoto, Takeharu Hayashi, Tomohiko Ai, Katherine G Spoonamore, Richard J Kovacs, Matteo Vatta, Mai Iizuka, Masumi Saito, Shotaro Wani, Yuichi Hiraoka, Akinori Kimura, Hidehito Kuroyanagi: Phosphorylation of the RSRSP stretch is critical for splicing regulation by RNA-Binding Motif Protein 20 (RBM20) through nuclear localization. Sci Rep. 2018.06; 8 (1): 8970. ( PubMed , DOI )

  2. Zhao Z, Hiraoka Y, Ogawa H, Tanaka K: Region-specific deletions of the glutamate transporter GLT1 differentially affect nerve injury-induced neuropathic pain in mice. Glia. 2018.05; ( PubMed , DOI )

  3. Miyasaka Y, Uno Y, Yoshimi K, Kunihiro Y, Yoshimura T, Tanaka T, Ishikubo H, Hiraoka Y, Takemoto N, Tanaka T, Ooguchi Y, Skehel P, Aida T, Takeda J, Mashimo T: CLICK: one-step generation of conditional knockout mice. BMC genomics. 2018.05; 19 (1): 318. ( PubMed , DOI )

  4. Menon R, Grund T, Zoicas I, Althammer F, Fiedler D, Biermeier V, Bosch OJ, Hiraoka Y, Nishimori K, Eliava M, Grinevich V, Neumann ID: Oxytocin Signaling in the Lateral Septum Prevents Social Fear during Lactation. Current biology : CB. 2018.04; 28 (7): 1066-1078.e6. ( PubMed , DOI )

  1. Hidema S, Fukuda T, Hiraoka Y, Mizukami H, Hayashi R, Otsuka A, Suzuki S, Miyazaki S, Nishimori K: Generation of Oxtr cDNA(HA)-Ires-Cre Mice for Gene Expression in an Oxytocin Receptor Specific Manner. Journal of cellular biochemistry. 2016.05; 117 (5): 1099-111. ( PubMed , DOI )

  2. Shizu Hidema, Tomokazu Fukuda, Yuichi Hiraoka, Hiroaki Mizukami, Ryotaro Hayashi, Ayano Otsuka, Shingo Suzuki, Shinji Miyazaki, and Katsuhiko Nishimori: Generation of Oxtr cDNA(HA) -Ires-Cre Mice for Gene Expression in an Oxytocin Receptor Specific Manner. Journal of Cellular Biochemistry. 2016.05; Volume 117, (Number 5 ): 1099-1111.

  3. Miyazaki S, Hiraoka Y, Hidema S, Nishimori K: Prenatal minocycline treatment alters synaptic protein expression, and rescues reduced mother call rate in oxytocin receptor-knockout mice. Biochemical and biophysical research communications. 2016.04; 472 (2): 319-23. ( PubMed , DOI )

  1. Benjamin Jurek, David A Slattery, Yuichi Hiraoka, Ying Liu, Katsuhiko Nishimori, Greti Aguilera, Inga D Neumann, Erwin H van den Burg: Oxytocin Regulates Stress-Induced Crf Gene Transcription through CREB-Regulated Transcription Coactivator 3. J. Neurosci.. 2015.09; 35 (35): 12248-12260. ( PubMed , DOI )

  2. Yuko Maejima, Rauza Sukma Rita, Putra Santoso, Masato Aoyama, Yuichi Hiraoka, Katsuhiko Nishimori, Darambazar Gantulga, Kenju Shimomura, Toshihiko Yada: Nasal oxytocin administration reduces food intake without affecting locomotor activity and glycemia with c-Fos induction in limited brain areas. Neuroendocrinology. 2015; 101 (1): 35-44. ( PubMed , DOI )

  3. Yoshiyuki Kasahara, Yuko Tateishi, Yuichi Hiraoka, Ayano Otsuka, Hiroaki Mizukami, Keiya Ozawa, Keisuke Sato, Shizu Hidema, Katsuhiko Nishimori: Role of the Oxytocin Receptor Expressed in the Rostral Medullary Raphe in Thermoregulation During Cold Conditions. Front Endocrinol (Lausanne). 2015; 6 180. ( PubMed , DOI )

  1. Yuko Maejima, Kazuya Sakuma, Putra Santoso, Darambazar Gantulga, Kenichi Katsurada, Yoichi Ueta, Yuichi Hiraoka, Katsuhiko Nishimori, Shigeyasu Tanaka, Kenju Shimomura, Toshihiko Yada: Oxytocinergic circuit from paraventricular and supraoptic nuclei to arcuate POMC neurons in hypothalamus. FEBS Lett.. 2014.11; 588 (23): 4404-4412. ( PubMed , DOI )

  1. Yuichi Hiraoka, Okiru Komine, Mai Nagaoka, Ning Bai, Katsuto Hozumi, Kohichi Tanaka: Delta-like 1 regulates Bergmann glial monolayer formation during cerebellar development. Mol Brain. 2013.05; 6 25. ( PubMed , DOI )

  2. Okamoto H, Aizawa H: Fear and anxiety regulation by conserved affective circuits. Neuron. 2013.05; 78 (3): 411-413.

  3. Aizawa H: Habenula and the asymmetric development of the vertebrate brain. Anat Sci Int.. 2013; 88 (1): 1-9.

  4. Hidenori Aizawa, Wanpeng Cui, Kohichi Tanaka, Hitoshi Okamoto: Hyperactivation of the habenula as a link between depression and sleep disturbance. Front Hum Neurosci. 2013; 7 826. ( PubMed , DOI )

  5. Aoki T, Kinoshita M, Aoki R, Agetsuma M, Aizawa H, Yamazaki M, Takahoko M, Amo R, Arata A, Higashijima S-I, Tsuboi T, Okamoto H.: Imaging of neural ensemble for the retrieval of a learned behavioral program. Neuron. 2013; 78 (5): 881-894.

  1. Aizawa H, Kobayashi M, Tanaka S, Fukai T, Okamoto H.: Molecular characterization of the subnuclei in rat habenula. J Comp Neurol.. 2012; 520 4051-4066.

  1. Okiru Komine, Mai Nagaoka, Yuichi Hiraoka, Mikio Hoshino, Yoshiya Kawaguchi, Warren S Pear, Kohichi Tanaka: RBP-J promotes the maturation of neuronal progenitors. Dev. Biol.. 2011.06; 354 (1): 44-54. ( PubMed , DOI )

  2. Okamoto H, Agetsuma M, Aizawa H: Genetic dissection of the zebrafish habenula, a possible switching board for selection of behavioral strategy to cope with fear and anxiety. Dev Neurobiol. 2011.05; ( PubMed , DOI )

  3. Hidenori Aizawa, Ryunosuke Amo, Hitoshi Okamoto: Phylogeny and ontogeny of the habenular structure. Front Neurosci. 2011; 5 138. ( PubMed , DOI )

  1. Agetsuma M, Aizawa H, Aoki T, Nakayama R, Takahoko M, Goto M, Sassa T, Amo R, Shiraki T, Kawakami K, Hosoya T, Higashijima S, Okamoto H: The habenula is crucial for experience-dependent modification of fear responses in zebrafish. Nat Neurosci. 2010.11; 13 (11): 1354-1356. ( PubMed , DOI )

  2. Amo R, Aizawa H, Takahoko M, Kobayashi M, Takahashi R, Aoki T, Okamoto H: Identification of the zebrafish ventral habenula as a homolog of the mammalian lateral habenula. J Neurosci. 2010.01; 30 (4): 1566-1574. ( PubMed , DOI )

  1. Soma M, Aizawa H, Ito Y, Maekawa M, Osumi N, Nakahira E, Okamoto H, Tanaka K, Yuasa S: Development of the mouse amygdala as revealed by enhanced green fluorescent protein gene transfer by means of in utero electroporation. J Comp Neurol. 2009.03; 513 (1): 113-128. ( PubMed , DOI )

  1. Okamoto H, Sato T, Aizawa H: Transgenic technology for visualization and manipulation of the neural circuits controlling behavior in zebrafish. Dev Growth Differ. 2008.06; 50 Suppl 1 S167-75. ( PubMed , DOI )

  2. Okamoto H, Aizawa H, Agetsuma M, Aoki T: [Visualization and manipulation of the emotional neural circuits in the zebrafish brain: study of mechanisms and roles for the asymmetry in the habenulo-interpeduncular projection]. Tanpakushitsu Kakusan Koso. 2008.03; 53 (4 Suppl): 475-481. ( PubMed )

  1. Sato T, Hamaoka T, Aizawa H, Hosoya T, Okamoto H: Genetic single-cell mosaic analysis implicates ephrinB2 reverse signaling in projections from the posterior tectum to the hindbrain in zebrafish. J Neurosci. 2007.05; 27 (20): 5271-5279. ( PubMed , DOI )

  2. Sassa T, Aizawa H, Okamoto H: Visualization of two distinct classes of neurons by gad2 and zic1 promoter/enhancer elements in the dorsal hindbrain of developing zebrafish reveals neuronal connectivity related to the auditory and lateral line systems. Dev Dyn. 2007.03; 236 (3): 706-718. ( PubMed , DOI )

  3. Aizawa H, Goto M, Sato T, Okamoto H: Temporally regulated asymmetric neurogenesis causes left-right difference in the zebrafish habenular structures. Dev Cell. 2007.01; 12 (1): 87-98. ( PubMed , DOI )

  1. Aizawa H, Bianco IH, Hamaoka T, Miyashita T, Uemura O, Concha ML, Russell C, Wilson SW, Okamoto H: Laterotopic representation of left-right information onto the dorso-ventral axis of a zebrafish midbrain target nucleus. Curr Biol. 2005.02; 15 (3): 238-243. ( PubMed , DOI )

  1. Aizawa H, Sato Y, Maekawa M, Fujisawa H, Hirata T, Yuasa S: Development of the amygdalohypothalamic projection in the mouse embryonic forebrain. Anat Embryol (Berl). 2004.07; 208 (4): 249-264. ( PubMed , DOI )

  1. Okazaki N, Kikuno R, Ohara R, Inamoto S, Aizawa H, Yuasa S, Nakajima D, Nagase T, Ohara O, Koga H: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003.02; 10 (1): 35-48. ( PubMed )

  1. Shigeki Yuasa, Mitsunari Nakajima, Hidenori Aizawa, Naruhiko Sahara, Ken-Ichi Koizumi, Tsuyoshi Sakai, Mihoko Usami, Shin-Ichiro Kobayashi, Hidehito Kuroyanagi, Hiroshi Mori, Haruhiko Koseki, Takuji Shirasawa: Impaired cell cycle control of neuronal precursor cells in the neocortical primordium of presenilin-1-deficient mice. J. Neurosci. Res.. 2002.11; 70 (3): 501-513. ( PubMed , DOI )

  1. 相澤秀紀, 崔万鵬, 田中光一, 岡本仁: うつ病の病態生理における手綱核神経回路の役割 生体の科学. 2014.02; 65 (1): 12-15.

  2. Amo R, Fredes F, Kinoshita M, Aoki R, Aizawa H, Agetsuma M, Aoki T, Shiraki T, Kakinuma H, Matsuda M, Yamazaki M, Takahoko M, Tsuboi T, Higashijima S, Miyasaka N, Koide T, Yabuki Y, Yoshihara Y, Fukai T, Okamoto H: The habenulo-raphe serotonergic circuit encodes an aversive expectation value essential for adaptive active avoidance of danger. Neuron. 2014.12; 84 1034-1048. ( PubMed , DOI )

  1. *Isomura Y, Takekawa T, Harukuni R, Handa T, Aizawa H, Takada M, Fukai T: Reward-modulated motor information in identified striatum neurons. The Journal of Neuroscience. 2013.06; 33 10209-10220. ( PubMed , DOI )

  2. Aizawa H, Yanagihara S, Kobayashi M, Niisato K, Takekawa T, Harukuni R, McHugh TJ, Fukai T, Isomura Y, *Okamoto H: The synchronous activity of lateral habenular neurons is essential for regulating hippocampal theta oscillation. The Journal of Neuroscience. 2013.05; 33 (20): 8909-8921. ( DOI )

  3. Aizawa H: Habenula and the asymmetric development of the vertebrate brain. Anatomical science international. 2013.01; 88 (1): 1-9. ( PubMed , DOI )

  1. Aizawa H, Kobayashi M, Tanaka S, Fukai T, Okamoto H: Molecular characterization of the subnuclei in rat habenula. The Journal of comparative neurology. 2012.12; 520 (18): 4051-4066. ( PubMed , DOI )

  1. *Isomura Y, Harukuni R, Takekawa T, Aizawa H, Fukai T: Microcircuitry coordination of cortical motor information in self-initiation of voluntary movements. Nature Neuroscience. 2009.12; 12 (12): 1586-1593. ( PubMed , DOI )

  1. 相澤秀紀, 岡本仁: ゼブラフィッシュ脳の左右非対称性とその発生機構 (特集 生物はなぜ左右非対称なのか?--その仕組みを探る) 細胞工学. 2008.06; 27 (6): 576-582.

  2. 岡本仁, 相澤秀紀: 気になる脳部位(第1回)手綱核 分子精神医学. 2008.04; 8 (2): 134-138.

  1. 相澤秀紀, 岡本仁: 脳の神経回路の左右差 メディカルバイオ. 2007.09; 4 (6): 82-88.

  1. 相澤秀紀, 岡本仁: Special Review 透明な魚で探る脳の左右非対称性 細胞工学. 2006.07; 25 (7): 780-784.

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