1. Kumada H, Itoh M, Tohda S: Effect of Ferroptosis Inducers and Inhibitors on Cell Proliferation in Acute Leukemia. Anticancer research. 2024.03; 44 (3): 1003-1010. ( PubMed , DOI )

  2. Goto Y, Nagamine Y, Hanafusa M, Kawahara T, Nawa N, Tateishi U, Ueki Y, Miyamae S, Wakabayashi K, Nosaka N, Miyazaki Y, Tohda S, Fujiwara T: Association of excess visceral fat and severe illness in hospitalized COVID-19 patients in Japan: a retrospective cohort study. International journal of obesity (2005). 2024.01; ( PubMed , DOI )

  1. Motomura, Y; Yoshifuji, K; Tachibana, T; Takase, H; Arai, A; Tanaka, K; Okada, K; Nogami, A; Umezawa, Y; Sakashita, C; Yamamoto, M; Mori, T; Nagao, T: Clinical factors for central nervous system progression and survival in primary vitreoretinal lymphoma BRITISH JOURNAL OF HAEMATOLOGY. 2023.12; ( PubMed , DOI )

  2. Azusa Yamazaki, Yoko Nukui, Takahiro Kameda, Ryoichi Saito, Yuki Koda, Naoya Ichimura, Shuji Tohda, Ryunosuke Ohkawa: Variation in presepsin and thrombomodulin levels for predicting COVID-19 mortality. Sci Rep. 2023.12; 13 (1): 21493. ( PubMed , DOI )

  3. Kotomi Noguchi, Mai Itoh, Chisuzu Ito, Shuji Tohda: Effects of MYC Inhibitors on the Growth of Acute Leukaemia Cells. Anticancer Res. 2023.07; 43 (7): 3023-3028. ( PubMed , DOI )

  4. Takatsuki Y., Takahashi Y., Nakajima J., Iwasaki Y., Nagano K., Tani-Sassa C., Yuasa S., Kanehira S., Sonobe K., Nukui Y., Takeuchi H., Tanimoto K., Tanaka Y., Kimura A., Ichimura N., and Tohda S.: Viral load of SARS-CoV-2 Omicron BA.5 is lower than that of BA.2 despite higher infectivity of BA.5. Immunity, Inflammation and Disease. 2023.02; 11 e783. ( DOI )

  5. Hanafusa M, Nawa N, Goto Y, Kawahara T, Miyamae S, Ueki Y, Nosaka N, Wakabayashi K, Tohda S, Tateishi U, Fujiwara T*: Effectiveness of remdesivir with corticosteroids for COVID-19 patients in intensive care unit: a hospital-based observational study. J Med Virol. 2023.01; 95 (1): e28168. ( PubMed , DOI )

  1. Nagao T, Yoshifuji K, Sadato D, Motomura Y, Saito M, Yamamoto K, Yamamoto K, Nogami A: Establishment and characterization of a new activated B-cell-like DLBCL cell line, TMD12. Experimental hematology. 2022.12; 116 37-49. ( PubMed , DOI )

  2. Nogami A., Sasaki K.: Therapeutic Advances in Immunotherapies for Hematological Malignancies Therapeutic Advances in Immunotherapies for Hematological Malignancies. International Journal of Molecular Sciences . 2022.09; 23 11526.

  3. Takahiro Mitsumura, Tsukasa Okamoto, Mizuho Tosaka, Takashi Yamana, Sho Shimada, Yuki Iijima, Rie Sakakibara, Sho Shibata, Takayuki Honda, Tsuyoshi Shirai, Masahiro Ishizuka, Junichi Aiboshi, Haruhiko Furusawa, Tomoya Tateishi, Meiyo Tamaoka, Hidenobu Shigemitsu, Hirokuni Arai, Yasuhiro Otomo, Shuji Tohda, Tatsuhiko Anzai, Kunihiko Takahashi, Shinsuke Yasuda, Yasunari Miyazaki: Association of SARS-CoV-2 RNA Copy Number with the COVID-19 Mortality Rate and Its Effect on the Predictive Performance of Mortality in Severe Cases. Jpn J Infect Dis. 2022.09; 75 (5): 504-510. ( PubMed , DOI )

  4. Mitsumura Takahiro, Okamoto Tsukasa, Tosaka Mizuho, Yamana Takashi, Shimada Sho, Iijima Yuki, Sakakibara Rie, Shibata Sho, Honda Takayuki, Shirai Tsuyoshi, Ishizuka Masahiro, Aiboshi Junichi, Furusawa Haruhiko, Tateishi Tomoya, Tamaoka Meiyo, Shigemitsu Hidenobu, Arai Hirokuni, Otomo Yasuhiro, Tohda Shuji, Anzai Tatsuhiko, Takahashi Kunihiko, Yasuda Shinsuke, Miyazaki Yasunari: Association of SARS-CoV-2 RNA Copy Number with the COVID-19 Mortality Rate and Its Effect on the Predictive Performance of Mortality in Severe Cases(タイトル和訳中) Japanese Journal of Infectious Diseases. 2022.09; 75 (5): 504-510. ( ichushi )

  5. Yusuke Ota, Chihiro Tani Sassa, Masayo Kashiwagi, Chikako Okawara, Shuji Tohda, Ryoichi Saito: Complete Genome Sequence of an Enterobacter roggenkampii Strain with Reduced Carbapenem Susceptibility Isolated from a Home-Visit Nursing Agency. Microbiol Resour Announc. 2022.08; e0035322. ( PubMed , DOI )

  6. Yuasa S, Nakajima J, Takatsuki Y, Takahashi Y, Tani-Sassa C, Iwasaki Y, Nagano K, Sonobe K, Yoshimoto T, Nukui Y, Takeuchi H, Tanimoto K, Tanaka Y, Kimura A, Ichimura N, Tohda S.: Viral load of SARS-CoV-2 Omicron is not high despite its high infectivity Journal of Medical Virology. 2022.07; 94 (11): 5543-5546. ( PubMed , DOI )

  7. Hamada Satomi, Sasaki Kanae, Kito Hotaka, Tooyama Yui, Ihara Kensuke, Aoyagi Eiko, Ichimura Naoya, Tohda Shuji, Sasano Tetsuo: Effect of the recording condition on the quality of a single-lead electrocardiogram(和訳中) Heart and Vessels. 2022.06; 37 (6): 1010-1026. ( ichushi )

  8. Satoru Aoyama, Shunichiro Yasuda, Huixin Li, Daisuke Watanabe, Yoshihiro Umezawa, Keigo Okada, Ayako Nogami, Osamu Miura, Norihiko Kawamata: A novel chimeric antigen receptor (CAR) system using an exogenous protease, in which activation of T cells is controlled by expression patterns of cell‑surface proteins on target cells. International Journal of Molecular Medicine. 2022.04; 49 (4): ( PubMed , DOI )

  9. Tani-Sassa C, Iwasaki Y, Ichimura N, Nagano K, Takatsuki Y, Yuasa S, Takahashi Y, Nakajima J, Sonobe K, Nukui Y, Takeuchi H, Tanimoto K, Tanaka Y, Kimura A, Tohda S.: Viral loads and profile of the patients infected with SARS-CoV-2 Delta, Alpha, or R.1 variants in Tokyo Journal of Medical Virology. 2022.04; 94 (4): 1707-1710. ( PubMed , DOI )

  10. Ryoichi Saito, Jun Nakajima, Isaac Prah, Masatomo Morita, Samiratu Mahazu, Yusuke Ota, Ayuka Kobayashi, Shuji Tohda, Hajime Kamiya, Hideyuki Takahashi, Makoto Ohnishi: Penicillin- and Ciprofloxacin-Resistant Invasive Neisseria meningitidis Isolates from Japan. Microbiol Spectr. 2022.04; e0062722. ( PubMed , DOI )

  11. Saito T, Itoh M, Tohda S: TYRO3 knockdown suppresses the growth of myeloid leukaemia cells. Anticancer Research. 2022.04; 42 (4): 1757-1761. ( PubMed , DOI )

  12. Kawahara Tomoki, Ueki Yutaka, Nawa Nobutoshi, Miyamae Shigeru, Hanafusa Mariko, Goto Yuki, Tohda Shuji, Fujiwara Takeo: Characteristics of SARS-CoV-2 super-spreaders in Japan JOURNAL OF INFECTION. 2022.02; 84 (2): e6-e9. ( PubMed , DOI )

  13. Kameda Takahiro, Horiuchi Yuna, Shimano Shitsuko, Yano Kouji, Lai Shao-Jui, Ichimura Naoya, Tohda Shuji, Kurihara Yuriko, Tozuka Minoru, Ohkawa Ryunosuke: Effect of myeloperoxidase oxidation and N-homocysteinylation of high-density lipoprotein on endothelial repair function BIOLOGICAL CHEMISTRY. 2022.02; 403 (3): 265-277. ( PubMed , DOI )

  14. Yamada Toru, Suzuki Risa, Ichimura Naoya, Mabuchi Suguru, Nagamine Yuiko, Sassa Chihiro, Tohda Shuji: Clinical Evaluation of Reverse Transcription-Polymerase Chain Reaction and Rapid Antigen Tests of Tongue Swabs for Detecting COVID-19(和訳中) Journal of Hospital General Medicine. 2022.01; 4 (1): 12-20. ( ichushi )

  1. Yusuke Ota, Natsune Hongou, Yoko Nukui, Ryuji Koike, Shuji Tohda, Ryoichi Saito: Evaluation of polymerase chain reaction-based open reading frame typing method for the clonality investigation of Clostridioides difficile isolates. Anaerobe. 2021.12; 72 102462. ( PubMed , DOI )

  2. Takahiro Kameda, Yuna Horiuchi, Shitsuko Shimano, Kouji Yano, Shao-Jui Lai, Naoya Ichimura, Shuji Tohda, Yuriko Kurihara, Minoru Tozuka, Ryunosuke Ohkawa: N-homocysteinylation of high-density lipoprotein on endothelial repair function. Biol Chem. 2021.08; ( PubMed , DOI )

  3. Nagano K, Tani-Sassa C, Iwasaki Y, Takatsuki Y, Yuasa S, Takahashi Y, Nakajima J, Sonobe K, Ichimura N, Nukui Y, Takeuchi H, Tanimoto K, Tanaka Y, Kimura A, Tohda S: SARS-CoV-2 R.1 lineage variants prevailed in Tokyo in March 2021. Journal of medical virology. 2021.07; ( PubMed , DOI )

  4. Mitsumura Takahiro, Okamoto Tsukasa, Shirai Tsuyoshi, Iijima Yuki, Sakakibara Rie, Honda Takayuki, Ishizuka Masahiro, Aiboshi Junichi, Tateishi Tomoya, Tamaoka Meiyo, Shigemitsu Hidenobu, Arai Hirokuni, Otomo Yasuhiro, Tohda Shuji, Anzai Tatsuhiko, Takahashi Kunihiko, Yasuda Shinsuke, Miyazaki Yasunari: Predictors associated with clinical improvement of SARS-CoV-2 pneumonia(和訳中) Journal of Infection and Chemotherapy. 2021.06; 27 (6): 857-863. ( ichushi )

  5. Azusa Yamazaki, Ryunosuke Ohkawa, Yuka Yamagata, Yuna Horiuchi, Shao-Jui Lai, Takahiro Kameda, Naoya Ichimura, Shuji Tohda, Minoru Tozuka: Apolipoprotein C-II and C-III preferably transfer to both high-density lipoprotein (HDL)2 and the larger HDL3 from very low-density lipoprotein (VLDL). Biol Chem. 2021.05; 402 (4): 439-449. ( PubMed , DOI )

  6. Sonoda Y, Itoh M, Tohda S: Effects of HOXA9 Inhibitor DB818 on the Growth of Acute Myeloid Leukaemia Cells. Anticancer Research. 2021.04; 41 (4): 1841-1847. ( PubMed , DOI )

  7. Yamazaki Azusa, Ohkawa Ryunosuke, Yamagata Yuka, Horiuchi Yuna, Lai Shao-Jui, Kameda Takahiro, Ichimura Naoya, Tohda Shuji, Tozuka Minoru: Apolipoprotein C-II and C-III preferably transfer to both high-density lipoprotein (HDL)(2) and the larger HDL3 from very low-density lipoprotein (VLDL) BIOLOGICAL CHEMISTRY. 2021.03; 402 (4): 439-449. ( PubMed , DOI )

  8. Mitsumura T, Okamoto T, Shirai T, Iijima Y, Sakakibara R, Honda T, Ishizuka M, Aiboshi J, Tateishi T, Tamaoka M, Shigemitsu H, Arai H, Otomo Y, Tohda S, Anzai T, Takahashi K, Yasuda S, Miyazaki Y: Predictors associated with clinical improvement of SARS-CoV-2 pneumonia. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2021.02; ( PubMed , DOI )

  9. Shitsuko Shimano, Ryunosuke Ohkawa, Mayu Nambu, Mai Sasaoka, Azusa Yamazaki, Yuki Fujii, Yuna Horiuchi, Shao-Jui Lai, Takahiro Kameda, Naoya Ichimura, Koji Fujita, Shuji Tohda, Minoru Tozuka: Marked Changes in Serum Amyloid A Distribution and High-Density Lipoprotein Structure during Acute Inflammation. Biomed Res Int. 2021; 2021 9241259. ( PubMed , DOI )

  10. Oba S, Hosoya T, Amamiya M, Mitsumura T, Kawata D, Sasaki H, Kamiya M, Yamamoto A, Ando T, Shimada S, Shirai T, Okamoto T, Tateishi T, Endo A, Aiboshi J, Nosaka N, Yamanouchi H, Ugawa T, Nagaoka E, Oi K, Tao S, Maejima Y, Tanaka Y, Tanimoto K, Takeuchi H, Tohda S, Hirakawa A, Sasano T, Arai H, Otomo Y, Miyazaki Y, Yasuda S: Arterial and Venous Thrombosis Complicated in COVID-19: A Retrospective Single Center Analysis in Japan. Frontiers in cardiovascular medicine. 2021; 8 767074. ( PubMed , DOI )

  11. Kuboki Mai, Umezawa Yoshihiro, Motomura Yotaro, Okada Keigo, Nogami Ayako, Nagao Toshikage, Miura Osamu, Yamamoto Masahide: Severe Motor Weakness Due to Disturbance in Peripheral Nerves Following Tisagenlecleucel Treatment IN VIVO. 2021; 35 (6): 3407-3411. ( PubMed , DOI )

  1. Salwa M Okasha, Mai Itoh, Shuji Tohda: Sirtuin 1 Activation Suppresses the Growth of T-lymphoblastic Leukemia Cells by Inhibiting NOTCH and NF-κB Pathways. Anticancer Res. 2020.06; 40 (6): 3155-3161. ( PubMed , DOI )

  2. Tatsuya Saito, Mai Itoh, Shuji Tohda: Metformin suppresses the growth of leukemia cells partly through downregulation of AXL receptor tyrosine kinase. Leuk Res. 2020.05; 94 106383. ( PubMed , DOI )

  3. Saito T, Itoh M, Tohda S: Metformin suppresses the growth of leukemia cells partly through downregulation of AXL receptor tyrosine kinase Leukemia Research. 2020.05; 94 106383.

  4. Yukino Usui, Alafate Ayibieke, Yuko Kamiichi, Shu Okugawa, Kyoji Moriya, Shuji Tohda, Ryoichi Saito: Impact of deoxycholate on Clostridioides difficile growth, toxin production, and sporulation. Heliyon. 2020.04; 6 (4): e03717. ( PubMed , DOI )

  5. Yukino Usui, Yoko Nukui, Ryuji Koike, Shuji Tohda, Ryoichi Saito: Draft Genome Sequence of a Clostridioides difficile Sequence Type 97 Strain Belonging to Hypervirulent Clade 2. Microbiol Resour Announc. 2020.04; 9 (14): e00245-20. ( PubMed , DOI )

  1. Akaza Miho, Kawabata Shigenori, Watanabe Taishi, Hasegawa Yuki, Iida Shintaro, Sasaki Toru, Adachi Yoshiaki, Sekihara Kensuke, Kanouchi Tadashi, Sumi Yuki, Okawa Atsushi, Yokota Takanori: Diagnosis of C8 radiculopathy by magnetospinogram(和訳中) 臨床神経学. 2019.11; 59 (Suppl.): S406. ( ichushi )

  2. Watanabe D, Nogami A, Okada K, Akiyama H, Umezawa Y, Miura O: FLT3-ITD Activates RSK1 to Enhance Proliferation and Survival of AML Cells by Activating mTORC1 and eIF4B Cooperatively with PIM or PI3K and by Inhibiting Bad and BIM. Cancers. 2019.11; 11 (12): ( PubMed , DOI )

  3. Yagi Yohsuke, Iida Shintaro, Kanouchi Tadashi, Kusunoki Susumu, Sobue Gen, Kaji Ryuji, Kuwabara Satoshi, Yokota Takanori, Glovenin-I CIDP Study Group: IVIg維持療法はCIDPの進行を抑制する(Maintenance treatment with IVIg for CIDP can prevent disease progression) 臨床神経学. 2019.11; 59 (Suppl.): S384. ( ichushi )

  4. Nukui Y, Chino T, Tani C, Sonobe K, Aiso Y, Tohda S, Koike R, Saito R: Molecular epidemiologic and clinical analysis of Helicobacter cinaedi bacteremia in Japan. Helicobacter. 2019.11; e12675. ( PubMed , DOI )

  5. Ryoichi Saito, Yukino Usui, Alafate Ayibieke, Jun Nakajima, Isaac Prah, Kazunari Sonobe, Yoshibumi Aiso, Shiori Ito, Yasuhiro Itsui, Yoshiro Hadano, Yoko Nukui, Ryuji Koike, Shuji Tohda: Hypervirulent clade 2, ribotype 019/sequence type 67 Clostridioides difficile strain from Japan. Gut Pathog. 2019.11; 11 54. ( PubMed , DOI )

  6. Nogami Ayako, Watanabe Daisuke, Okada Keigo, Akiyama Hiroki, Umezawa Yoshihiro, Nagao Toshikage, Tohda Shuji, Miura Osamu: FLT3-ITD Enhances Proliferation and Survival of AML Cells through Activation of RSK1 to Upregulate the mTORC1/eIF4F Pathway Cooperatively with PIM or PI3K and to Inhibit Bad and Bim BLOOD. 2019.11; 134 ( DOI )

  7. Kaminaka S., Akaza M., Kawabata S., Watanabe T., Miyano Y., Iida S., Sasaki T., Adachi Y., Sekihara K., Kanouchi T., Sumi Y., Okawa A., Yokota T.: Diagnosis of C8 radiculopathy by magnetospinogram JOURNAL OF THE NEUROLOGICAL SCIENCES. 2019.10; 405 ( DOI )

  8. Yoko Nukui, Alafate Ayibieke, Makoto Taniguchi, Yoshibumi Aiso, Yuka Shibuya, Kazunari Sonobe, Jun Nakajima, Saki Kanehira, Yoshiro Hadano, Shuji Tohda, Ryuji Koike, Ryoichi Saito: Whole-genome analysis of EC129, an NDM-5-, CTX-M-14-, OXA-10- and MCR-1-co-producing Escherichia coli ST167 strain isolated from Japan. J Glob Antimicrob Resist. 2019.09; 18 148-150. ( PubMed , DOI )

  9. Itoh M, Okuhashi Y, Takahashi Y, Sonoda Y, Mohammad S, Saito T, Shiratori E, Tohda S: Hypoxia Up-regulates HIF Expression While Suppressing Cell Growth and NOTCH Activity in Leukaemia Cells. Anticancer Research. 2019.08; 39 (8): 4165-4170. ( PubMed , DOI )

  10. Hamada S, Hasegawa Y, Oono A, Suzuki A, Takahashi N, Nishimura T, Koyama T, Hagihara M, Tohda S, Furukawa T, Hirao K, Sasano T: Author Correction: Differential Assessment of Factor Xa Activity and Global Blood Coagulability Utilizing Novel Dielectric Coagulometry. Scientific reports. 2019.03; 9 (1): 4957. ( PubMed , DOI )

  11. Yuna Horiuchi, Ryunosuke Ohkawa, Shao-Jui Lai, Shitsuko Shimano, Michio Hagihara, Shuji Tohda, Takahiro Kameda, Minoru Tozuka: Usefulness of apolipoprotein B-depleted serum in cholesterol efflux capacity assays using immobilized liposome-bound gel beads. Biosci. Rep.. 2019.03; ( PubMed , DOI )

  12. Nogami Ayako, Okada Keigo, Ishida Shinya, Akiyama Hiroki, Umezawa Yoshihiro, Miura Osamu: Inhibition of the STAT5/Pim Kinase Axis Enhanecs Cytotoxic Effects of Proteasome Inhibitors on FLT3-ITD-Positive Cells by Cooperatively Inhibiting the mTORC1/4EBP1/S6K/Mcl-1 Pathway TRANSLATIONAL ONCOLOGY. 2019.02; 12 (2): 336-349. ( PubMed , DOI )

  13. Kawaguchi-Ihara Noriko, Zhao Yan, Nakamura Suzune, Suzuki Keiko, Zhang Yi, Tohda Shuji, Murohashi Ikuo: Chloroquine Inhibits Self-Renewal of Blast Progenitors Synergistically With Phytochemicals or Nonsteroidal Anti-inflammatory Drugs in Hematological Malignant Cell Lines ANTICANCER RESEARCH. 2019.01; 39 (1): 87-98. ( PubMed , DOI )

  14. Akiyama Hiroki, Umezawa Yoshihiro, Ishida Shinya, Okada Keigo, Nogami Ayako, Miura Osamu: Inhibition of USP9X induces apoptosis in FLT3-ITD-positive AML cells cooperatively by inhibiting the mutant kinase through aggresomal translocation and inducing oxidative stress CANCER LETTERS. 2019; 453 84-94. ( PubMed , DOI )

  1. Akaza Miho, Akaza Itaru, Kanouchi Tadashi, Sasano Tetsuo, Sumi Yuki, Yokota Takanori: Study for association between glycemic variability and diabetic neuropathy assessed by NCS(和訳中) 臨床神経学. 2018.12; 58 (Suppl.): S419. ( ichushi )

  2. Yuki Okuhashi, Mai Itoh, Shuji Tohda: GLI1 and CTNNB1 Knockdown Activates NOTCH and mTOR Signalling in NB4 Myeloid Leukaemia Cells. Anticancer Research. 2018.11; 38 (11): 6329-6332.

  3. Okuhashi Yuki, Itoh Mai, Tohda Shuji: GLI1 and CTNNB1 Knockdown Activates NOTCH and mTOR Signalling in NB4 Myeloid Leukaemia Cells ANTICANCER RESEARCH. 2018.11; 38 (11): 6329-6332. ( PubMed , DOI )

  4. Hamada Satomi, Hasegawa Yuki, Oono Ai, Suzuki Anna, Takahashi Naomi, Nishimura Takuro, Koyama Takatoshi, Hagihara Michio, Tohda Shuji, Furukawa Tetsushi, Hirao Kenzo, Sasano Tetsuo: Differential Assessment of Factor Xa Activity and Global Blood Coagulability Utilizing Novel Dielectric Coagulometry SCIENTIFIC REPORTS. 2018.10; 8 (1): 16129. ( PubMed , DOI )

  5. Wang S, Itoh M, Shiratori E, Ohtaka M, Tohda S: NOTCH activation promotes glycosyltransferase expression in human myeloid leukemia cells. Hematology reports. 2018.09; 10 (3): 7576. ( PubMed , DOI )

  6. Wang S, Itoh M, Shiratori E, Ohtaka M, Tohda S: NOTCH activation promotes glycosyltransferase expression in human myeloid leukemia cells Hematology Reports. 2018.09; 10 7576.

  7. Miho Akaza, Itaru Akaza, Tadashi Kanouchi, Tetsuo Sasano, Yuki Sumi, Takanori Yokota: Nerve conduction study of the association between glycemic variability and diabetes neuropathy. Diabetol Metab Syndr. 2018.09; 10 69. ( PubMed , DOI )

  8. Yonekura S, Itoh M, Shiratori E, Ohtaka M, Tohda S: FOXP3 knockdown inhibits the proliferation and reduces NOTCH1 expression of T cell acute lymphoblastic leukemia cells. BMC research notes. 2018.08; 11 (1): 582. ( PubMed , DOI )

  9. Yonekura S, Itoh M, Shiratori E, Ohtaka M, Tohda S: FOXP3 knockdown inhibits the proliferation and reduces NOTCH1 expression of T cell acute lymphoblastic leukemia cells BMC Research Notes. 2018.08; 11 582.

  10. Ishida S, Akiyama H, Umezawa Y, Okada K, Nogami A, Oshikawa G, Nagao T, Miura O: Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2. Oncotarget. 2018.06; 9 (42): 26834-26851. ( PubMed , DOI )

  11. Horiuchi Yuna, Lai Shao-Jui, Yamazaki Azusa, Nakamura Ayaka, Ohkawa Ryunosuke, Yano Kouji, Kameda Takahiro, Okubo Shigeo, Shimano Shitsuko, Hagihara Michio, Tohda Shuji, Tozuka Minoru: VALIDATION AND APPLICATION OF A NOVEL CHOLESTEROL EFFLUX ASSAY USING IMMOBILIZED LIPOSOMES AS A SUBSTITUTE FOR CULTURED CELLS ATHEROSCLEROSIS SUPPLEMENTS. 2018.06; 32 59.

  12. Misawa S, Kuwabara S, Sato Y, Yamaguchi N, Nagashima K, Katayama K, Sekiguchi Y, Iwai Y, Amino H, Suichi T, Yokota T, Nishida Y, Kanouchi T, Kohara N, Kawamoto M, Ishii J, Kuwahara M, Suzuki H, Hirata K, Kokubun N, Masuda R, Kaneko J, Yabe I, Sasaki H, Kaida KI, Takazaki H, Suzuki N, Suzuki S, Nodera H, Matsui N, Tsuji S, Koike H, Yamasaki R, Kusunoki S, Japanese Eculizumab Trial for GBS (JET-GBS) Study Group.: Safety and efficacy of eculizumab in Guillain-Barré syndrome: a multicentre, double-blind, randomised phase 2 trial. The Lancet. Neurology. 2018.06; 17 (6): 519-529. ( PubMed , DOI )

  13. Yuna Horiuchi, Shao-Jui Lai, Azusa Yamazaki, Ayaka Nakamura, Ryunosuke Ohkawa, Kouji Yano, Takahiro Kameda, Shigeo Okubo, Shitsuko Shimano, Michio Hagihara, Shuji Tohda, Minoru Tozuka: Validation and application of a novel cholesterol efflux assay using immobilized liposomes as a substitute for cultured cells. Biosci. Rep.. 2018.04; 38 (2): ( PubMed , DOI )

  14. Ogihara Shinji, Saito Ryoichi, Sawabe Etsuko, Kozakai Takahiro, Shima Mari, Aiso Yoshibumi, Fujie Toshihide, Nukui Yoko, Koike Ryuji, Hagihara Michio, Tohda Shuji: Molecular typing of methicillin-resistant Staphylococcus aureus: Comparison of PCR-based open reading frame typing, multilocus sequence typing, and Staphylococcus protein A gene typing Journal of Infection and Chemotherapy. 2018.04; 24 (3-4): 312-314. ( ichushi )

  15. Shinji Ogihara, Ryoichi Saito, Etsuko Sawabe, Takahiro Kozakai, Mari Shima, Yoshibumi Aiso, Toshihide Fujie, Yoko Nukui, Ryuji Koike, Michio Hagihara, Shuji Tohda: Molecular typing of methicillin-resistant Staphylococcus aureus: Comparison of PCR-based open reading frame typing, multilocus sequence typing, and Staphylococcus protein A gene typing. J. Infect. Chemother.. 2018.04; 24 (4): 312-314. ( PubMed , DOI )

  16. Koda Y, Itoh M, Tohda S: Effects of MERTK inhibitors UNC569 and UNC1062 on the growth of acute myeloid leukaemia cells. Anticancer Research. 2018.01; 38 (1): 199-204.

  17. Yuki Koda, Mai Itoh, Shuji Tohda: Effects of MERTK Inhibitors UNC569 and UNC1062 on the Growth of Acute Myeloid Leukaemia Cells. Anticancer Res.. 2018; 38 (1): 199-204. ( PubMed , DOI )

  1. Keigo Okada, Ayako Nogami, Shinya Ishida, Hiroki Akiyama, Cheng Chen, Yoshihiro Umezawa and Osamu Miura: FLT3-ITD induces expression of Pim kinases through STAT5 to confer resistance to the PI3K/Akt pathway inhibitors on leukemic cells by enhancing the mTORC1/Mcl-1 pathway Oncotarget. 2017.12; 9 8870-8886.

  2. Yoshihiro Umezawa, Hiroki Akiyama, Keigo Okada, Shinya Ishida, Ayako Nogami, Gaku Oshikawa, Tetsuya Kurosu, Osamu Miura: Molecular mechanisms for enhancement of stromal cell-derived factor 1-induced chemotaxis by platelet endothelial cell adhesion molecule 1 (PECAM-1). Journal of Biological Chemistry. 2017.12; 292 (48): 19639-19655.

  3. Erika Shiratori, Mai Itoh, Shuji Tohda: MYD88 Inhibitor ST2825 Suppresses the Growth of Lymphoma and Leukaemia Cells. Anticancer Research. 2017.11; 37 (11): 6203-6209. ( PubMed , DOI )

  4. Shuta Toru, Tadashi Kanouchi, Takanori Yokota, Yosuke Yagi, Akira Machida, Takayoshi Kobayashi: Utility of Autonomic Function Tests to Differentiate Dementia with Lewy Bodies and Parkinson Disease with Dementia from Alzheimer Disease. Eur. Neurol.. 2017.11; 79 (1-2): 27-32. ( PubMed , DOI )

  5. Mika Ohtaka, Mai Itoh, Shuji Tohda: BMI1 Inhibitors Down-regulate NOTCH Signaling and Suppress Proliferation of Acute Leukemia Cells. Anticancer Research. 2017.11; 37 (11): 6047-6053. ( PubMed , DOI )

  6. Kanouchi T., Sekiguchi T., Iida S., Akaza M., Yokota T.: Temporal relation between local disease progression in the onset site and regional spread of motor symptoms in amyotrophic lateral sclerosis JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 558-559. ( DOI )

  7. Kanai K., Yokota T., Shibuya K., Nakazato T., Kanouchi T., Iwai Y., Oyama G., Shimo Y., Shimizu T., Hattori N., Kuwabara S.: Increased motor axonal persistent sodium currents is associated with rapid regional spreading in amyotrophic lateral sclerosis JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 558. ( DOI )

  8. Murakawa Miyako, Asahina Yasuhiro, Nagata Hiroko, Nakagawa Mina, Kakinuma Sei, Nitta Sayuri, Kawai-Kitahata Fukiko, Otani Satoshi, Kaneko Shun, Miyoshi Masato, Tsunoda Tomoyuki, Asano Yu, Sato Ayako, Itsui Yasuhiro, Azuma Seishin, Nouchi Toshihiko, Furumoto Yohei, Asano Tooru, Chuganji Yoshimichi, Tohda Shuji, Watanabe Mamoru: ITPA gene variation and ribavirin-induced anemia in patients with genotype 2 chronic hepatitis C treated with sofosbuvir plus ribavirin Hepatology Research. 2017.10; 47 (11): 1212-1218. ( ichushi )

  9. Yamada A., Numasawa Y., Hattori T., Ozaki K., Ishibashi S., Nishida Y., Kanouchi T., Sanjo N., Takanori Y.: Signal changes of skeletal muscle MRI in peripheral nerve disorders JOURNAL OF THE NEUROLOGICAL SCIENCES. 2017.10; 381 1068. ( DOI )

  10. Yoshimoto Ryoto, Watanabe Ken, Uchida Emi, Suwa Shihoko, Tohda Shuji, Hatano Masahiko, Miura Osamu, Fukuda Tetsuya: IVNS1ABP/Nd1は新規治療標的分子として難治性リンパ腫に強発現する(IVNS1ABP/Nd1 is highly expressed in refractory lymphoma as a novel therapeutic target molecule) 臨床血液. 2017.09; 58 (9): 1655. ( ichushi )

  11. Okuhashi Y, Itoh M, Tohda S: Hedgehog stimulation suppresses clonogenicity and activates NOTCH signalling in T-lymphoblastic leukaemia Jurkat cells. Anticancer Research . 2017.09; 37 (9): 5005-5009.

  12. Miyako Murakawa, Yasuhiro Asahina, Hiroko Nagata, Mina Nakagawa, Sei Kakinuma, Sayuri Nitta, Fukiko Kawai-Kitahata, Satoshi Otani, Shun Kaneko, Masato Miyoshi, Tomoyuki Tsunoda, Yu Asano, Ayako Sato, Yasuhiro Itsui, Seishin Azuma, Toshihiko Nouchi, Yohei Furumoto, Tooru Asano, Yoshimichi Chuganji, Shuji Tohda, Mamoru Watanabe: ITPA gene variation and ribavirin-induced anemia in patients with genotype 2 chronic hepatitis C treated with sofosbuvir plus ribavirin. Hepatol. Res. 2017.07; 29 (5): 584-593. ( PubMed , DOI )

  13. Miyako Murakawa, Yasuhiro Asahina, Fukiko Kawai-Kitahata, Mina Nakagawa, Sayuri Nitta, Satoshi Otani, Hiroko Nagata, Shun Kaneko, Yu Asano, Tomoyuki Tsunoda, Masato Miyoshi, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Yasuhito Tanaka, Sayuki Iijima, Kaoru Tsuchiya, Namiki Izumi, Shuji Tohda, Mamoru Watanabe: Hepatic IFNL4 expression is associated with non-response to interferon-based therapy through the regulation of basal interferon-stimulated gene expression in chronic hepatitis C patients. J. Med. Virol. 2017.07; 89 (7): 1241-1247. ( PubMed , DOI )

  14. Yuki Okuhashi, Mai Itoh, Shuji Tohda: Hedgehog Stimulation Suppresses Clonogenicity and Activates NOTCH Signalling in T-lymphoblastic Leukaemia Jurkat Cells. Anticancer Res.. 2017.05; 37 (9): 5005-5009. ( PubMed , DOI )

  15. S Nogami, N Kawaguchi-Ihara, E Shiratori, M Ohtaka, M Itoh, S Tohda: Detection of the MYD88 mutation by the combination of the allele-specific PCR and quenching probe methods. Int J Lab Hematol. 2017.04; 39 (2): 163-168. ( PubMed , DOI )

  16. Nogami S, Kwaguchi-Ihara N, Shiratori E, Ohtaka M, Itoh M, Tohda S: Detection of the MYD88 mutation by the combination of the allele-specific PCR and quenching probe methods. International Journal of Laboratory Hematology . 2017.04; 39 (2): 163-168.

  17. Iwasawa Eri, Ohkubo Takuya, Kanouchi Tadashi, Kanda Takashi, Mizusawa Hidehiro, Yokota Takanori: Long-term Effects of Intravenous Cyclophosphamide in Combination with Mesna Provided Intravenously and via Bladder Perfusion in a Patient with Severe Multifocal Motor Neuropathy INTERNAL MEDICINE. 2017; 56 (14): 1893-1896. ( PubMed , DOI )

  1. Gene Igawa, Mika Casey, Etsuko Sawabe, Yoko Nukui, Shu Okugawa, Kyoji Moriya, Ryuji Koike, Shuji Tohda, Ryoichi Saito: Comparison of agar dilution and broth microdilution methods for Clostridium difficile antimicrobial susceptibility testing. J Glob Antimicrob Resist. 2016.12; 43-45. ( PubMed , DOI )

  2. Hiroko Nagata, Mina Nakagawa, Yuki Nishimura-Sakurai, Yu Asano, Tomoyuki Tsunoda, Masato Miyoshi, Shun Kaneko, Fumio Goto, Satoshi Otani, Fukiko Kawai-Kitahata, Miyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Naoko Tojo, Shuji Tohda, Yasuhiro Asahina, Mamoru Watanabe: Serial measurement of Wisteria floribunda agglutinin positive Mac-2-binding protein is useful for predicting liver fibrosis and the development of hepatocellular carcinoma in chronic hepatitis C patients treated with IFN-based and IFN-free therapy. Hepatol Int. 2016.11; 10 (6): 956-964. ( PubMed , DOI )

  3. Shinji Ogihara, Ryoichi Saito, Etsuko Sawabe, Michio Hagihara, Shuji Tohda: First Japanese case of infectious endocarditis due to Enterococcus faecalis small-colony variants. J. Infect. Chemother. 2016.10; 22 (10): 716-719. ( PubMed , DOI )

  4. Yoshihiro Umezawa, Tetsuya Kurosu, Hiroki Akiyama, Nang Wu, Ayako Nogami, Toshikage Nagao, Osamu Miusa: Down regulation of Chk1 by p53 plays a role in synergistic induction of apoptosis by chemotherapeutics and inhibitors for Jak2 or BCR/ABL in hematopoietic cells. Oncotarget. 2016.06; ( PubMed )

  5. Noriko Kawaguchi-Ihara, Mai Itoh, Ikuo Murohashi, Shuji Tohda: Establishment of a quenching probe method for detection of NPM1 mutations in acute myeloid leukemia cells. Oncol Lett. 2016.04; 11 (4): 2429-2432. ( PubMed , DOI )

  6. Mari Kamiya, Peter Y Shane, Makoto Soejima, Shuji Tohda, Nobuyuki Miyasaka, Hitoshi Kohsaka: IgG4-Related Sialoadenitis with a Skin Lesion and Multiple Mononeuropathies Suggesting Coexistent Cryoglobulinemic Vasculitis. Intern. Med.. 2016; 55 (10): 1355-1361. ( PubMed , DOI )

  1. Nogami Ayako, Oshikawa Gaku, Okada Keigo, Fukutake Shusaku, Umezawa Yoshihiro, Nagao Toshikage, Kurosu Tetsuya, Miura Osamu: FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia. Oncotarget. 2015.04; 6 (11): 9189-9205. ( PubMed )

  2. Mitsuma S, Van den Bergh P, Rajabally YA, Van Parijs V, Martin-Lamb D, Sonoo M, Inaba A, Shimizu T, Isose S, Sato Y, Komori T, Misawa S, Kuwabara S, The Tokyo Metropolitan Neuromuscular Electrodiagnosis Study Group(including Kanouchi T): Effects of low frequency filtering on distal compound muscle action potential duration for diagnosis of CIDP: A Japanese-European multicenter prospective study. Clinical Neurophysiology. 2015; 126 1805-1810.

  1. Yusuke Takahashi, Mai Itoh, Nobuo Nara, Shuji Tohda: Effect of EPH-ephrin signaling on the growth of human leukemia cells. Anticancer Research. 2014.06; 34 (6): 2913-2918. ( PubMed )

  2. Saito R, Takahashi R, Sawabe E, Koyano S, Takahashi Y, Shima M, Ushizawa H, Fujie T, Tosaka N, Kato Y, Moriya K, Tohda S, Tojo N, Koike R, Kubota T: First Report of KPC-2 Carbapenemase-Producing Klebsiella pneumoniae in Japan. Antimicrob Agents Chemother. 2014.05; 58 (5): 2961-2963. ( PubMed , DOI )

  3. Takebe I, Sawabe E, Ohkusu K, Tojo N, Tohda S: Catheter-related Bloodstream Infection by Tsukamurella inchonensis in an Immunocompromised Patient. J Clin Microbiol. 2014.03; 52 (6): 2251-2253. ( PubMed , DOI )

  4. Mizuno N, Kanamori E, Saito H, Murakami N, Tojo N, Tohda S: A Case of Gray Platelet Syndrome Masked by Immune Thrombocytopenia at Presentation. Acta Haematol. 2014.02; 132 (2): 163-165. ( PubMed , DOI )

  5. Teruhiko Sekiguchi, Tadashi Kanouchi, Kazumoto Shibuya, Yu-ichi Noto, Yohsuke Yagi, Akira Inaba, Keisuke Abe, Sonoko Misawa, Satoshi Orimo, Takayoshi Kobayashi, Tomoyuki Kamata, Masanori Nakagawa, Satoshi Kuwabara, Hidehiro Mizusawa, Takanori Yokota: Spreading of amyotrophic lateral sclerosis lesions--multifocal hits and local propagation? J. Neurol. Neurosurg. Psychiatr.. 2014.01; 85 (1): 85-91. ( PubMed , DOI )

  6. Tohda S: NOTCH signaling roles in acute myeloid leukemia cell growth and interaction with other stemness-related signals. Anticancer Research. 2014; 34 (11): 6259-6264. ( PubMed )

  7. Takahashi Y, Itoh M, Nara N, Tohda S: Effect of EPH-ephrin signaling on the growth of human leukemia cells. Anticancer Research. 2014; 34 2913-2918.

  8. Nagao T, Kurosu T, Umezawa Y, Nogami A, Oshikawa G, Tohda S, Yamamoto M, Miura O: Proliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera. PLoS ONE. 2014; 9 (1): e84746. ( PubMed , DOI )

  1. Okuhashi Y, Itoh M, Nara N, Tohda S: NOTCH knockdown affects the proliferation and mTOR signaling of leukemia cells. Anticancer Res. 2013.10; 33 (10): 4293-4298. ( PubMed )

  2. Yonekura S, Itoh M, Okuhashi Y, Takahashi Y, Ono A, Nara N, Tohda S: Effects of the HIF1 inhibitor, echinomycin, on growth and NOTCH signalling in leukaemia cells. Anticancer Res. 2013.08; 33 (8): 3099-3103. ( PubMed )

  3. Ono A, Oike R, Okuhashi Y, Takahashi Y, Itoh M, Nara N, Tohda S: Comparative effects of PP242 and rapamycin on mTOR signalling and NOTCH signalling in leukemia cells. Anticancer Research. 2013.03; 33 (3): 809-813. ( PubMed )

  1. Kanamori E, Itoh M, Tojo N, Koyama T, Nara N, Tohda S: Flow cytometric analysis of Notch1 and Jagged1 expression in normal blood cells and leukemia cells. Exp Ther Med. 2012.09; 4 (3): 397-400. ( PubMed , DOI )

  2. Ono A, Okuhashi Y, Takahashi Y, Itoh M, Nara N, Tohda S: Advantages of the quenching probe method over other PCR-based methods for detection of the JAK2 V617F mutation. Oncol Lett. 2012.08; 4 (2): 205-208. ( PubMed , DOI )

  3. Kanouchi Tadashi, Ohkubo Takuya, Yokota Takanori: Can regional spreading of amyotrophic lateral sclerosis motor symptoms be explained by prion-like propagation? J Neurol Neurosurg Psychiatry. 2012.07; 83 (7): 739-745. ( PubMed , DOI )

  4. Takahashi Y, Ishigaki T, Okuhashi Y, Ono A, Itoh M, Nara N, Tohda S: Effect of BMP4 on the growth and clonogenicity of human leukemia and lymphoma cells. Anticancer Res. 2012.07; 32 (7): 2813-2817. ( PubMed )

  5. Kitamura Y, Sawabe E, Ohkusu K, Tojo N, Tohda S: First report of sepsis caused by Rhodococcus corynebacterioides in a patient with myelodysplastic syndrome. J Clin Microbiol. 2012.03; 50 (3): 1089-1091. ( PubMed , DOI )

  1. Siegers GM, Dhamko H, Wang XH, Mathieson AM, Kosaka Y, Felizardo TC, Medin JA, Tohda S, Schueler J, Fisch P, Keating A: Human Vδ1 γδ T cells expanded from peripheral blood exhibit specific cytotoxicity against B-cell chronic lymphocytic leukemia-derived cells. Cytotherapy. 2011.07; 13 (6): 753-764. ( PubMed , DOI )

  2. Kawaguchi-Ihara N, Okuhashi Y, Itoh M, Murohashi I, Nara N, Tohda S: Promotion of the self-renewal capacity of human leukemia cells by sonic hedgehog protein. Anticancer Res. 2011.03; 31 (3): 781-784. ( PubMed )

  3. Okuhashi Y, Itoh M, Nara N, Tohda S: Effects of combination of notch inhibitor plus hedgehog inhibitor or Wnt inhibitor on growth of leukemia cells. Anticancer Res. 2011.03; 31 (3): 893-896. ( PubMed )

  4. Nara N, Suzuki T, Tohda S: The current medical education system in the world. J Med Dent Sci. 2011; 58 (2): 79-83. ( PubMed )

  1. Okuhashi Y, Itoh M, Arai A, Nara N, Tohda S: Gamma-secretase inhibitors induce erythroid differentiation in erythroid leukemia cell lines. Anticancer Res. 2010.10; 30 (10): 4071-4074. ( PubMed )

  2. Ishigaki T, Sasaki K, Watanabe K, Nakamura N, Toyota S, Kobayashi H, Tohda S: Amplification of IGH/CCND1 fusion gene in a primary plasma cell leukemia case. Cancer Genet Cytogenet. 2010.08; 201 (1): 62-65. ( PubMed , DOI )

  3. Okuhashi Y, Nara N, Tohda S: Effects of gamma-secretase inhibitors on the growth of leukemia cells. Anticancer Res. 2010.02; 30 (2): 495-498. ( PubMed )

  1. Kawahara T, Kawaguchi-Ihara N, Okuhashi Y, Itoh M, Nara N, Tohda S: Cyclopamine and quercetin suppress the growth of leukemia and lymphoma cells. Anticancer Res. 2009.11; 29 (11): 4629-4632. ( PubMed )

  2. Fu L, Katsube K, Tohda S: Transition of cleaved Notch1 and gene expression changes in myeloblastic leukemia cells stimulated with notch ligands. Anticancer Res. 2009.10; 29 (10): 3967-3970. ( PubMed )

  3. Itoh M, Fu L, Tohda S: NF-kappaB activation induced by Notch ligand stimulation in acute myeloid leukemia cells. Oncol Rep. 2009.09; 22 (3): 631-634. ( PubMed )

  4. Nara N, Beppu M, Tohda S, Suzuki T: The introduction and effectiveness of simulation-based learning in medical education. Intern Med. 2009; 48 (17): 1515-1519. ( PubMed )

  1. Nemoto Y, Kanai T, Tohda S, Totsuka T, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Fukuda T, Miura O, Yagita H, Watanabe M: Negative feedback regulation of colitogenic CD4+ T cells by increased granulopoiesis. Inflamm Bowel Dis. 2008.11; 14 (11): 1491-1503. ( PubMed , DOI )

  2. Kawaguchi-Ihara N, Murohashi I, Nara N, Tohda S: Promotion of the self-renewal capacity of human acute leukemia cells by Wnt3A. Anticancer Res. 2008.09; 28 (5A): 2701-2704. ( PubMed )

  3. Kobayashi T, Terada Y, Kuwana H, Tanaka H, Okado T, Kuwahara M, Tohda S, Sakano S, Sasaki S: Expression and function of the Delta-1/Notch-2/Hes-1 pathway during experimental acute kidney injury. Kidney Int. 2008.06; 73 (11): 1240-1250. ( PubMed , DOI )

  4. Morita-Hoshi Y, Tohda S, Miura O, Nara N: An autopsy case of multicentric Castleman's disease associated with interstitial nephritis and secondary AA amyloidosis. Int J Hematol. 2008.01; 87 (1): 69-74. ( PubMed , DOI )

  1. Fu L, Nara N, Tohda S: Involvement of Notch signaling in myelodysplastic syndrome. Leuk Res. 2007.08; 31 (8): 1160-1161. ( PubMed , DOI )

  2. Hiromi Akeboshi, Yasunori Chiba, Yoshiko Kasahara, Minako Takashiba, Yuki Takaoka, Mai Ohsawa, Youichi Tajima, Ikuo Kawashima, Daisuke Tsuji, Kohji Itoh, Hitoshi Sakuraba, Yoshifumi Jigami: Production of recombinant beta-hexosaminidase A, a potential enzyme for replacement therapy for Tay-Sachs and Sandhoff diseases, in the methylotrophic yeast Ogataea minuta. Applied and Environmental Microbiology. 2007.08; 73 (15): 4805-4812. ( PubMed , DOI )

  3. Kogoshi H, Sato T, Koyama T, Nara N, Tohda S: Gamma-secretase inhibitors suppress the growth of leukemia and lymphoma cells. Oncol Rep. 2007.07; 18 (1): 77-80. ( PubMed )

  4. Jihwa Chung, Takatoshi Koyama, Mai Ohsawa, Aya Shibamiya, Asuka Hoshi, Shinsaku Hirosawa: 1,25(OH)(2)D(3) blocks TNF-induced monocytic tissue factor expression by inhibition of transcription factors AP-1 and NF-kappaB. Lab. Invest.. 2007.06; 87 (6): 540-547. ( PubMed , DOI )

  5. Ikuo Kawashima, Mai Ohsawa, Tomoko Fukushige, Yoshihisa Nagayama, Yo Niida, Masaharu Kotani, Youichi Tajima, Takuro Kanekura, Tamotsu Kanzaki, Hitoshi Sakuraba: Cytochemical analysis of storage materials in cultured skin fibroblasts from patients with I-cell disease. Clinica Chimica Acta. 2007.03; 378 (1-2): 142-146. ( PubMed , DOI )

  1. Tohda S, Sato T, Kogoshi H, Fu L, Sakano S, Nara N: Establishment of a novel B-cell lymphoma cell line with suppressed growth by gamma-secretase inhibitors. Leuk Res. 2006.11; 30 (11): 1385-1390. ( PubMed , DOI )

  2. Fu L, Kogoshi H, Nara N, Tohda S: NOTCH1 mutations are rare in acute myeloid leukemia. Leuk Lymphoma. 2006.11; 47 (11): 2400-2403. ( PubMed , DOI )

  3. Ikuo Kawashima, Ichiro Takeuchi, Mai Ohsawa, Masaharu Kotani, Youichi Tajima, Takayuki Inomata, Tohru Izumi, Hitoshi Sakuraba: Phospholipid storage in the myocardium of a unique Japanese case of idiopathic cardiomyopathy. Clinica Chimica Acta. 2006.10; 372 (1-2): 154-157. ( PubMed , DOI )

  4. Yutaka Tatano, Tsutomu Takahashi, Daisuke Tsuji, Naohiro Takeuchi, Kohji Tsuta, Goro Takada, Mai Ohsawa, Hitoshi Sakuraba, Kohji Itoh: Significant decrease in tropoelastin gene expression in fibroblasts from a Japanese Costello syndrome patient with impaired elastogenesis and enhanced proliferation. Journal of Biochemistry. 2006.08; 140 (2): 193-200. ( PubMed , DOI )

  5. Yukako Oheda, Masaharu Kotani, Mai Ohsawa, Hitoshi Sakuraba, Yoshito Kadota, Yutaka Tatano, Jun Kuwahara, Kohji Itoh: Elimination of abnormal sialylglycoproteins in fibroblasts with sialidosis and galactosialidosis by normal gene transfer and enzyme replacement. Glycobiology. 2006.04; 16 (4): 271-280. ( PubMed , DOI )

  6. Hitoshi Sakuraba, Mai Ohsawa, Ikuo Kawashima, Youichi Tajima, Masaharu Kotani, Toshio Ohshima, Yasunori Chiba, Minako Takashiba, Yoshifumi Jigami, Tomoko Fukushige, Tamotsu Kanzaki, Kohji Itoh: Comparison of the effects of agalsidase alfa and agalsidase beta on cultured human Fabry fibroblasts and Fabry mice. Journal of Human Genetics. 2006; 51 (3): 180. ( PubMed , DOI )

  7. Hitoshi Sakuraba, Yasunori Chiba, Masaharu Kotani, Ikuo Kawashima, Mai Ohsawa, Youichi Tajima, Yuki Takaoka, Yoshifumi Jigami, Hiroshi Takahashi, Yukihiko Hirai, Takashi Shimada, Yasuhiro Hashimoto, Kumiko Ishii, Toshihide Kobayashi, Kazuhiko Watabe, Tomoko Fukushige, Tamotsu Kanzaki: Corrective effect on Fabry mice of yeast recombinant human alpha-galactosidase with N-linked sugar chains suitable for lysosomal delivery. Journal of Human Genetics. 2006; 51 (4): 341-352. ( PubMed , DOI )

  1. Kogoshi H, Tohda S, Fu L, Koyama T, Nara N: Effect of notch ligands on in vitro sensitivity to chemo-therapeutic drugs in leukemia and lymphoma cells. Oncol Rep. 2005.09; 14 (3): 723-726. ( PubMed )

  2. Tohda S, Kogoshi H, Murakami N, Sakano S, Nara N: Diverse effects of the Notch ligands Jagged1 and Delta1 on the growth and differentiation of primary acute myeloblastic leukemia cells. Exp Hematol. 2005.05; 33 (5): 558-563. ( PubMed , DOI )

  3. Murata-Ohsawa M, Tohda S, Kogoshi H, Sakano S, Nara N: The Notch ligand, Delta-1, alters retinoic acid (RA)-induced neutrophilic differentiation into monocytic and reduces RA-induced apoptosis in NB4 cells. Leuk Res. 2005.02; 29 (2): 197-203. ( PubMed , DOI )

  4. Mai Ohsawa, Masaharu Kotani, Youichi Tajima, Daisuke Tsuji, Yasuhiro Ishibashi, Aya Kuroki, Kohji Itoh, Kazuhiko Watabe, Kazunori Sango, Shoji Yamanaka, Hitoshi Sakuraba: Establishment of immortalized Schwann cells from Sandhoff mice and corrective effect of recombinant human beta-hexosaminidase A on the accumulated GM2 ganglioside. Journal of Human Genetics. 2005; 50 (9): 460-467. ( PubMed , DOI )

  1. Murata-Ohsawa M, Tohda S, Kogoshi H, Nara N: The Notch ligand, Delta-1, reduces TNF-alpha-induced growth suppression and apoptosis by decreasing activation of caspases in U937 cells. Int J Mol Med. 2004.11; 14 (5): 861-866. ( PubMed )

  2. Murata-Ohsawa M, Tohda S, Nara N: Cellular analysis of growth suppression induced by the Notch ligands, Delta-1 and Jagged-1 in two myeloid leukemia cell lines. Int J Mol Med. 2004.08; 14 (2): 223-226. ( PubMed )

  3. Murata-Ohsawa M, Tohda S, Sakano S, Nara N: The Notch ligand, Delta-1, partially inhibits GM-CSF-induced differentiation and apoptosis along with reducing the cleavage of PARP in U937 cells. Int J Mol Med. 2004.03; 13 (3): 419-423. ( PubMed )

  1. Tohda S, Murata-Ohsawa M, Sakano S, Nara N: Notch ligands, Delta-1 and Delta-4 suppress the self-renewal capacity and long-term growth of two myeloblastic leukemia cell lines. Int J Oncol. 2003.05; 22 (5): 1073-1079. ( PubMed )

  2. Mai Ohsawa, Takatoshi Koyama, Nobuo Nara, Shinsaku Hirosawa: Induction of tissue factor expression in human monocytic cells by protease inhibitors through activating activator protein-1 (AP-1) with phosphorylation of Jun-N-terminal kinase and p38. Thromb. Res.. 2003; 112 (5-6): 313-320. ( PubMed , DOI )

  1. Tohda S, Sakano S, Ohsawa M, Murakami N, Nara N: A novel cell line derived from de novo acute myeloblastic leukaemia with trilineage myelodysplasia which proliferates in response to a Notch ligand, Delta-1 protein. Br J Haematol. 2002.05; 117 (2): 373-378. ( PubMed )

  2. Koyama T, Ohsawa M, Nakazawa F, Shibamiya S : Anticoagulant effects of synthetic retinoids and activated vitamin D3 (1,25(OH)2D3) analogs Modern Trends in Skin Pharmacology. 2002;

  1. Tohda S, Murakami N, Nara N: Human herpesvirus 8 DNA in HIV-negative Japanese patients with multicentric Castleman's disease and related diseases. Int J Mol Med. 2001.11; 8 (5): 549-551. ( PubMed )

  2. Tohda S, Nara N: Expression of Notch1 and Jagged1 proteins in acute myeloid leukemia cells. Leuk Lymphoma. 2001.07; 42 (3): 467-472. ( PubMed )

  1. M Ohsawa, T Koyama, K Yamamoto, S Hirosawa, S Kamei, R Kamiyama: 1alpha,25-dihydroxyvitamin D(3) and its potent synthetic analogs downregulate tissue factor and upregulate thrombomodulin expression in monocytic cells, counteracting the effects of tumor necrosis factor and oxidized LDL. Circulation. 2000.12; 102 (23): 2867-2872. ( PubMed )

  2. Tohda S, Ohkusa T: Resolution of refractory idiopathic thrombocytopenic purpura after eradication of Helicobacter pylori. Am J Hematol. 2000.12; 65 (4): 329-330. ( PubMed )

  3. Tohda S, Murakami N, Nara N: Polymerase chain reaction detection of rearranged immunoglobulin heavy chain DNA in plasma samples is useful in the diagnosis of B-cell lymphoma. Int J Hematol. 2000.07; 72 (1): 74-78. ( PubMed )

  4. M Ohsawa, T Koyama, M Shibakura, S Kamei, S Hirosawa: Arsenic trioxide (As2O3) gradually downregulates tissue factor expression without affecting thrombomodulin expression in acute promyelocytic leukemia cells. Leukemia. 2000.05; 14 (5): 941-943. ( PubMed )

  1. Tohda S, Sakashita C, Fukuda T, Murakami N, Nara N: Establishment of a double Philadelphia chromosome-positive acute lymphoblastic leukemia-derived cell line, TMD5: effects of cytokines and differentiation inducers on growth of the cells. Leuk Res. 1999.03; 23 (3): 255-261. ( PubMed )

  1. T Koyama, M Shibakura, M Ohsawa, R Kamiyama, S Hirosawa: Anticoagulant effects of 1alpha,25-dihydroxyvitamin D3 on human myelogenous leukemia cells and monocytes. Blood. 1998.07; 92 (1): 160-167. ( PubMed )

  2. M Shibakura, T Koyama, M Ohsawa, R Kamiyama, S Hirosawa: A retinoic acid receptor-alpha (RAR alpha) selective agonist modulates procoagulant activity of acute promyelocytic cells and induces their differentiation into neutrophils. Blood. 1998.01; 91 (2): 724-725. ( PubMed )

  3. Tohda S, Koyama N, Tanaka M, Kida Y, Murakami N, Nara N: A case of atypical chronic myeloid leukemia regarded as MDS with myeloproliferative features. Acta Haematol. 1998; 100 (4): 191-194. ( PubMed )

  1. Tohda S, Nara N: Phosphorylation of signaling proteins in factor-independent myeloid leukemia cell lines. Int J Oncol. 1997.10; 11 (4): 843-847. ( PubMed )

  2. Tohda S, Maruyama M, Nara N: Molecular typing of methicillin-resistant Staphylococcus aureus by polymerase chain reaction: distribution of the typed strains in hospitals. Intern Med. 1997.10; 36 (10): 694-699. ( PubMed )

  3. Nara N, Kurokawa H, Tohda S, Tomiyama J, Nagata K, Tanikawa S: Effect of vesnarinone, a quinolinone derivative, on the growth of leukemic blasts in acute myelogenous leukemia. Exp Hematol. 1997.03; 25 (3): 199-204. ( PubMed )

  1. Imai Y, Yasuhara S, Hanafusa N, Ohsaka A, Enokihara H, Tomizuka H, Sonoyama M, Miura YS, Tohda S, Nara N, Takahashi A: Clonal involvement of eosinophils in therapy-related myelodysplastic syndrome with eosinophilia, translocation t(1;7) and lung cancer. Br J Haematol. 1996.12; 95 (4): 710-714. ( PubMed )

  2. Tohda S, Kurokawa H, Nara N: Relation of protein kinase A and protein kinase C to signaling pathways of hematopoietic factors in leukemia cell lines. Int J Oncol. 1996.03; 8 (3): 521-524. ( PubMed )

  1. Nara N, Kurokawa H, Tohda S, Tomiyama J, Nagata K, Tanikawa S: The effect of basic and acidic fibroblast growth factors (bFGF and aFGF) on the growth of leukemic blast progenitors in acute myelogenous leukemia. Exp Hematol. 1995.08; 23 (9): 1030-1034. ( PubMed )

  2. Tohda S, Kurokawa H, Nara N: Diversity and similarity in signaling pathways of hematopoietic growth factors in human leukemia cell lines. Leukemia. 1995.05; 9 (5): 879-883. ( PubMed )

  1. Koyama T, Hirosawa S, Kawamata N, Tohda S, Aoki N: All-trans retinoic acid upregulates thrombomodulin and downregulates tissue-factor expression in acute promyelocytic leukemia cells: distinct expression of thrombomodulin and tissue factor in human leukemic cells. Blood. 1994.11; 84 (9): 3001-3009. ( PubMed )

  2. Tohda S, Shudo K, Minden M: The effects of retinoic Acid analogs on the blast cells of acute myeloblastic-leukemia in culture. Int J Oncol. 1994.06; 4 (6): 1311-1314. ( PubMed )

  3. Tohda S, Minden MD: Modulation of growth factor receptors on acute myeloblastic leukemia cells by retinoic acid. Jpn J Cancer Res. 1994.04; 85 (4): 378-383. ( PubMed )

  4. Nara N, Tohda S: Successful treatment of refractory pure red cell aplasia by buserelin acetate. Acta Haematol. 1994; 92 (1): 42-45. ( PubMed )

  1. Tohda S, Ashman L, Minden M: The role of stroma cells on the proliferation and C-kit expression of acute myeloblastic-leukemia cells. Int J Oncol. 1993.12; 3 (6): 1141-1147. ( PubMed )

  2. Murohashi I, Tohda S, Imai Y, Hirai Y, Nara N: Growth potentiating activity of endogenous production of interleukin-1 and tumor necrosis factor alpha in blast cells of acute myeloblastic leukemia. Exp Hematol. 1993.07; 21 (7): 846-851. ( PubMed )

  3. Tohda S, Yang GS, Ashman LK, McCulloch EA, Minden MD: Relationship between c-Kit expression and proliferation in acute myeloblastic leukemia cell lines. J Cell Physiol. 1993.02; 154 (2): 410-418. ( PubMed , DOI )

  1. Nara N, Chen GJ, Murohashi I, Tohda S, Imai Y, Tomiyama J, Nagata K, Suzuki T, Tanikawa S, Shiina S: The in vitro growth patterns and drug sensitivities of leukemic blast progenitors among the subtypes of acute myelocytic leukemia. Exp Hematol. 1992.08; 20 (7): 904-908. ( PubMed )

  2. Tohda S, Curtis JE, McCulloch EA, Minden MD: Comparison of the effects of all-trans and cis-retinoic acid on the blast stem cells of acute myeloblastic leukemia in culture. Leukemia. 1992.07; 6 (7): 656-661. ( PubMed )

  3. Kawamata N, Maruyama Y, Toda S, Takase K, Akiyama H, Sakamaki H, Onozawa Y: A case of chronic lymphocytic leukaemia with myeloid associated antigen. Br J Haematol. 1992.01; 80 (1): 129-130. ( PubMed )

  4. Suzuki T, Tohda S, Nagata K, Imai Y, Murohashi I, Nara N: Enhanced effect of mutant granulocyte-colony-stimulating factor (KW-2228) on the growth of normal and leukemic hemopoietic progenitor cells in comparison with recombinant human granulocyte-colony-stimulating factor (G-CSF). Acta Haematol. 1992; 87 (4): 181-189. ( PubMed )

  5. Nara N, Tohda S, Suzuki T, Nagata K, Tanikawa S, Imai Y, Tomiyama J, Shiina S: Comparison of the proliferative activity and sensitivity to cytosine arabinoside of leukemic blast progenitors in acute myeloblastic leukemia at diagnosis and in relapse. Acta Haematol. 1992; 88 (1): 17-21. ( PubMed )

  6. Suzuki T, Bessho M, Hirashma K, Tohda S, Nagata K, Imai Y, Nara N: Interleukin-6 reduces the optimal growth in vitro of leukemic blast progenitors from acute myeloblastic leukemia patients. Acta Haematol. 1992; 87 (1-2): 63-68. ( PubMed )

  7. Tohda S, Nara N, Tanikawa S, Imai Y, Murakami N, Aoki N: Pure red cell aplasia following autoimmune haemolytic anaemia. Cell-mediated suppression of erythropoiesis as a possible pathogenesis of pure red cell aplasia. Acta Haematol. 1992; 87 (1-2): 98-102. ( PubMed )

  1. Tohda S, Minden MD, McCulloch EA: Interactions between retinoic acid and colony-stimulating factors affecting the blast cells of acute myeloblastic leukemia. Leukemia. 1991.11; 5 (11): 951-957. ( PubMed )

  2. Tohda S, Nara N, Murohashi I, Aoki N: Establishment of an interleukin-3-dependent leukemic cell line from a patient with chronic lymphocytic leukemia in the acute phase. Blood. 1991.10; 78 (7): 1789-1794. ( PubMed )

  3. Suzuki T, Bessho M, Hirashima K, Tohda S, Nagata K, Morio T, Imai Y, Nara N: Enhancement by transforming growth factor-beta 1 (TGF-beta 1) of the proliferation of leukemic blast progenitors stimulated with IL-3. J Cell Physiol. 1991.09; 148 (3): 396-403. ( PubMed , DOI )

  4. Yamashita Y, Tohda S, Nagata K, Suzuki T, Imai Y, Nara N: The in vitro effect of vincristine on the blast cell renewal in acute myeloblastic leukemia. Jpn J Med. 1991.09; 30 (5): 412-419. ( PubMed )

  5. Tohda S, Nara N, Imai Y, Aoki N: Effect of protein kinase inhibitors on the proliferation of leukemic cells stimulated by granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor or interleukin-3. Leukemia. 1991.09; 5 (9): 813-814. ( PubMed )

  6. Imai Y, Nara N, Tohda S, Nagata K, Suzuki T, Nagasawa M, Murohashi I, Aoki N: Antiproliferative and differentiative effects of recombinant interleukin-4 on a granulocyte colony-stimulating factor-dependent myeloblastic leukemic cell line. Blood. 1991.07; 78 (2): 471-478. ( PubMed )

  7. Imai Y, Tohda S, Nagata K, Suzuki T, Nara N, Aoki N: Effects of recombinant interleukin 4 on the growth and differentiation of blast progenitors stimulated with G-CSF, GM-CSF and IL-3 from acute myeloblastic leukaemia patients. Br J Haematol. 1991.06; 78 (2): 173-179. ( PubMed )

  1. Nara N, Tohda S, Suzuki T, Nagata K, Yamashita Y, Imai Y, Maruyama Y, Tomiyama J: Effects of N4-behenoyl-1-beta-D-arabinofuranosylcytosine on blast progenitors of acute myeloblastic leukemia. Cancer Res. 1990.12; 50 (23): 7587-7592. ( PubMed )

  2. Suzuki T, Morio T, Tohda S, Nagata K, Yamashita Y, Imai Y, Aoki N, Hirashima K, Nara N: Effects of interleukin-6 and granulocyte colony-stimulating factor on the proliferation of leukemic blast progenitors from acute myeloblastic leukemia patients. Jpn J Cancer Res. 1990.10; 81 (10): 979-986. ( PubMed )

  3. Tohda S, Morio T, Suzuki T, Nagata K, Kamiyama T, Imai Y, Nara N, Aoki N: Richter syndrome with two B cell clones possessing different surface immunoglobulins and immunoglobulin gene rearrangements. Am J Hematol. 1990.09; 35 (1): 32-36. ( PubMed )

  4. Nara N, Suzuki T, Nagata K, Tohda S, Yamashita Y, Nakamura Y, Imai Y, Morio T, Minamihisamatsu M: Granulocyte colony-stimulating factor-dependent growth of an acute myeloblastic leukemia cell line. Jpn J Cancer Res. 1990.06; 81 (6-7): 625-631. ( PubMed )

  5. Tohda S, Suzuki T, Nagata K, Nara N, Aoki N: Successful treatment of a patient with posthepatitic severe aplastic anemia with bolus methylprednisolone. Jpn J Med. 1990.03; 29 (2): 191-194. ( PubMed )

  6. Murohashi I, Tohda S, Suzuki T, Nagata K, Yamashita Y, Nara N: Mechanism of action of interleukin 1 on the progenitors of blast cells in acute myeloblastic leukemia. Exp Hematol. 1990.02; 18 (2): 133-137. ( PubMed )

  7. Tohda S, Suzuki T, Nagata K, Nara N, Aoki N: Haematopoietic suppressing activity of gamma-interferon in serum and bone marrow of aplastic anaemia patients. Nippon Ketsueki Gakkai Zasshi. 1990.02; 53 (1): 14-20. ( PubMed )

  8. Nara N, Tohda S, Suzuki T, Nagata K, Yamashita Y, Imai Y, Morio T, Bessho M, Shibuya A, Adachi Y: Terminal differentiation to mature neutrophils and eosinophils in suspension culture of the blast progenitors in acute myeloblastic leukemia. Hematol Pathol. 1990; 4 (3): 125-134. ( PubMed )

  9. Nara N, Tohda S, Nagata K, Suzuki T, Yamashita Y, Imai Y: Effect of platelet-derived growth factor on the proliferation of blast progenitors from acute myeloblastic leukemia patients. Acta Haematol. 1990; 83 (4): 187-192. ( PubMed )

  10. Maruyama Y, Tohda S, Nagata K, Suzuki T, Murohashi I, Nara N: Role of humoral and cellular factors on the growth of blast progenitors of acute myeloblastic leukemia in serum-free culture. Hematol Pathol. 1990; 4 (3): 115-123. ( PubMed )

  11. Tohda S, Nagata K, Suzuki T, Nara N: Comparative effects of busulfan, cytosine arabinoside and adriamycin on different maturation stages of normal human bone marrow cells. Acta Haematol. 1990; 83 (1): 16-21. ( PubMed )

  1. Nagata K, Tohda S, Suzuki T, Nara N: Effects of recombinant human tumor necrosis factor on the self-renewal capacity of leukemia blast progenitors in acute myeloblastic leukemia. Leukemia. 1989.09; 3 (9): 626-630. ( PubMed )

  2. Nara N, Tohda S, Nagata K, Suzuki T, Yamashita Y: Inhibition of the in vitro growth of blast progenitors from acute myeloblastic leukemia patients by transforming growth factor-beta (TGF-beta). Leukemia. 1989.08; 3 (8): 572-577. ( PubMed )

  3. Murohashi I, Tohda S, Suzuki T, Nagata K, Yamashita Y, Nara N: Autocrine growth mechanisms of the progenitors of blast cells in acute myeloblastic leukemia. Blood. 1989.07; 74 (1): 35-41. ( PubMed )

  4. Murohashi I, Tohda S, Suzuki T, Nagata K, Yamashita Y, Nara N, Aoki N: Expression of interleukin 1 beta receptors on blast cells in acute myeloblastic leukemia: comparison with interleukin 1 beta proliferative activity. Cancer Res. 1989.06; 49 (12): 3431-3435. ( PubMed )

  5. Murohashi I, Tohda S, Suzuki T, Nagata K, Yamashita Y, Nara N: Specific binding of radioiodinated human GM-CSF to the blast cells of acute myeloblastic leukemia. Leuk Res. 1989; 13 (7): 599-604. ( PubMed )

  1. Kimura M, Nishiyama Y, Ueda H, Kitajo A, Arimatsu T, Kuboki M, Takahata A, Saito M, Sakashita C, Okada K, Umezawa Y, Nagao T, Yamamoto M, Tohda S, Tanabe M, Mori T, Nogami A: Perioperative management of laparoscopic cholecystectomy in a patient with paroxysmal nocturnal haemoglobinuria undergoing ravulizumab treatment 2022; 63 (4): 260-264. ( PubMed , DOI )

  1. Nogami A, Yamamoto M, Yamamoto K, Ito M, Umezawa Y, Tohda S, Miura O, Fukuda T: Marginal zone lymphoma-like primary bone marrow lymphoma with long-term pancytopenia preceding diagnosis Rinsho ketsueki. 2020.10; 61 (10): 1469-1475. ( PubMed , DOI )

  2. Satoshi Koi, Kosuke Arai, Ayako Nogami, Hayato Toma, Masahide Yamamoto, Osamu Miura, Toshikage Nagao: Impaired hematopoiesis due to copper deficiency in a hemodialysis patient supplemented with zinc. Rinsho Ketsueki. 2020.10; 61 (10): 1487-1491. ( PubMed , DOI )

  1. Megumi Akiyama, Kota Yoshifuji, Tetsuya Fukuda, Shuji Tohda, Tohru Miki, Osamu Miura, Masahide Yamamoto: Fulminant visceral disseminated varicella-zoster virus infection without skin involvement in a patient with autoimmune hemolytic anemia on prednisolone therapy. Rinsho Ketsueki. 2016.04; 57 (4): 467-471. ( PubMed , DOI )

  2. Yokota T, Kanouchi T, Ohkubo T: ALS: Quantitative analysis of disease progression from a new point of view 2015 Annual report of the research committee of CNS degenerative diseases, The ministry of health, labour and welfare of Japan. 2016.03; 58-61.

  1. Sekiguchi T, Kanouchi T, Yokota T: ALS as the TDP-43 proteinopathy: does the lesion spread noncontiguously ? Neurological Medicine. 2014.12; 81 (6): 644-649.

  2. Kanouchi Tadashi: Myasthenia Gravis -New clinical standards. Diagnosis and Differential diagnosis. Tensilon test 2014.09; 32 (9): 1011-1012.

  3. Kanouchi Tadashi: Repetitive nerve stimulation test 2014.01; 166 25-32.

  1. Koyama T, Ohsawa M, Nakazawa F, Yamamoto K: Anticoagulant effects of activated D3 (1,25(OH)2D3) and its potent synthetic analogs Recent advances in clinical pharmacology. 2001.06; 22 111-117.

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