Nasir K Bashiruddin, Mikihito Hayashi, Masanobu Nagano, Yan Wu, Yukiko Matsunaga, Junichi Takagi, Tomoki Nakashima, Hiroaki Suga: Development of cyclic peptides with potent in vivo osteogenic activity through RaPID-based affinity maturation. Proc Natl Acad Sci U S A. 2020.12; 117 (49): 31070-31077. ( PubMed , DOI )
Yosuke Tsuchiya, Mikihito Hayashi, Katashi Nagamatsu, Takehito Ono, Masaki Kamakura, Takanori Iwata, Tomoki Nakashima: The key royal jelly component 10-hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-κB signaling downstream of FFAR4. J. Biol. Chem.. 2020.07; ( PubMed , DOI )
Yoshitaka Kameo, Yuki Miya, Mikihito Hayashi, Tomoki Nakashima, Taiji Adachi: In silico experiments of bone remodeling explore metabolic diseases andtheir drug treatment. Science Advances. 2020.03; 6 (10): eaax0938.
Takehito Ono, Mikihito Hayashi, Fumiyuki Sasaki, Tomoki Nakashima: RANKL biology: bone metabolism, the immune system, and beyond. Inflamm Regen. 2020.02; 40 2. ( PubMed , DOI )
Fumiyuki Sasaki, Mikihito Hayashi, Yuki Mouri, Satoshi Nakamura, Taiji Adachi, Tomoki Nakashima: Mechanotransduction via the Piezo1-Akt pathway underlies Sost suppression in osteocytes. Biochemical and Biophysical Research Communications. 2020.01; 521 (3): 806-813.
Mikihito Hayashi, Tomoki Nakashima, Noriko Yoshimura, Kazuo Okamoto, Sakae Tanaka, Hiroshi Takayanagi.: Osteocyte Sema3A orchestrates estrogen action and counteracts bone aging. Cell Metabolism. 2019.03; 29 627-637.
Yusoon Kim, Mikihito Hayashi, Takehito Ono, Tetsuya Yoda, Hiroshi Takayanagi, Tomoki Nakashima.: Suppression of hematopoietic cell kinase ameliorates the bone destruction associated with inflammation. Modern Rheumatology. 2018.11;
Y Fukushima-Nakayama, Takehito Ono, M Hayashi, M Inoue, H Wake, Takashi Ono, T Nakashima: Reduced Mastication Impairs Memory Function. J. Dent. Res.. 2017.08; 96 (9): 1058-1066. ( PubMed , DOI )
Ayumi Shoji-Matsunaga, Takehito Ono, Mikihito Hayashi, Hiroshi Takayanagi, Keiji Moriyama, Tomoki Nakashima: Osteocyte regulation of orthodontic force-mediated tooth movement via RANKL expression. Sci Rep. 2017.08; 7 (1): 8753. ( PubMed , DOI )
Tomoki Nakashima, Mikihito Hayashi, Takanobu Fukunaga, Kosaku Kurata, Masatsugu Oh-Hora, Jian Q Feng, Lynda F Bonewald, Tatsuhiko Kodama, Anton Wutz, Erwin F Wagner, Josef M Penninger, Hiroshi Takayanagi: Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nat. Med.. 2011.10; 17 (10): 1231-1234. ( PubMed , DOI )