1. Lihong Cheng, Caiyue Shi, Xixi Li, Toshiro Matsui: Impact of Peptide Transport and Memory Function in the Brain Nutrients. 2024.09; ( DOI )

  2. Cryo-electron tomography of the actin cytoskeleton and membrane organization during lamellipodia formation using optogenetics 2024.08; ( DOI )

  3. Cheng L, Shi C, Nakamura S, Esaki N, Ichiba Y, Tanaka M, Sakai K, Matsui T: Adiponectin-Receptor Agonistic Dipeptide Tyr-Pro Stimulates the Acetylcholine Nervous System in NE-4C Cells. Journal of agricultural and food chemistry. 2024.04; 72 (13): 7121-7129. ( PubMed , DOI )

  4. Toshifumi Asano, Philipp Sasse, Takao Nakata: Development of a Cre-recombination-based color-switching reporter system for cell fusion detection. Biochem Biophys Res Commun. 2024.01; 690 149231. ( PubMed , DOI )

  5. Aiko Takada, Toshifumi Asano, Ken-Ichi Nakahama, Takashi Ono, Takao Nakata, Tomohiro Ishii: Development of an optogenetics tool, Opto-RANK, for control of osteoclast differentiation using blue light. Sci Rep. 2024.01; 14 (1): 1749. ( PubMed , DOI )

  1. Cheng L, Tanaka M, Yoshino A, Nagasato Y, Takata F, Dohgu S, Matsui T: A memory-improving dipeptide, Tyr-Pro, can reach the mouse brain after oral administration. Scientific reports. 2023.10; 13 (1): 16908. ( PubMed , DOI )

  1. Tomoya Uchimura, Toshifumi Asano, Takao Nakata, Akitsu Hotta, Hidetoshi Sakurai: A muscle fatigue-like contractile decline was recapitulated using skeletal myotubes from Duchenne muscular dystrophy patient-derived iPSCs. Cell Reports Medicine. 2021.06; 2 (6): 100298. ( PubMed , DOI )

  2. Shogo Yoshihara , Xuguang Jiang , Momo Morikawa , Tadayuki Ogawa , Sotaro Ichinose , Hirooki Yabe , Akiyoshi Kakita , Manabu Toyoshima , Yasuto Kunii , Takeo Yoshikawa , Yosuke Tanaka , Nobutaka Hirokawa : Betaine ameliorates schizophrenic traits by functionally compensating for KIF3-based CRMP2 transport Cell Reports. 2021.04; 35 (2): 108971. ( PubMed , DOI )

  3. Hironori Inaba, Qianqian Miao, Takao Nakata: Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling. J Biol Chem. 2021.01; 100290. ( PubMed , DOI )

  1. Takanobu Shimizu, Takeshi Nakamura, Hironori Inaba, Hiroaki Iwasa, Junichi Maruyama, Kyoko Arimoto-Matsuzaki, Takao Nakata, Hiroshi Nishina, Yutaka Hata: The RAS-interacting chaperone UNC119 drives the RASSF6-MDM2-p53 axis and antagonizes RAS-mediated malignant transformation. J. Biol. Chem.. 2020.08; 295 (32): 11214-11230. ( PubMed , DOI )

  1. Xiang, L; Wu, QB; Cheng, LH; Sun, KY; Li, J; Yoshida, M; Qi, JH: Leptin and Adiponectin Signaling Pathways Are Involved in the Antiobesity Effects of Peanut Skin Extract OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2019.10; 2019 1-14. ( PubMed , DOI )

  2. Manabu Toyoshima,Xuguang Jiang, Tadayuki Ogawa, Tetsuo Ohnishi, Shogo Yoshihara, Shabeesh Balan, Takeo Yoshikawa, Nobutaka Hirokawa: Enhanced carbonyl stress induces irreversible multimerization of CRMP2 in schizophrenia pathogenesis Life Science Alliance. 2019.10; 2 (5): lsa.201900478. ( PubMed , DOI )

  1. Moe Sato, Toshifumi Asano, Jun Hosomichi, Takashi Ono, Takao Nakata: Optogenetic manipulation of intracellular calcium by BACCS promotes differentiation of MC3T3-E1 cells. Biochemical and Biophysical Research Communications. 2018.11; 506 (3): 716-722. ( PubMed , DOI )

  2. Bian, LL; Cao, SN; Cheng, LH; Nakazaki, A; Nishikawa, T; Qi, JH: Semi-synthesis and Structure-Activity Relationship of Neuritogenic Oleanene Derivatives CHEMMEDCHEM. 2018.09; 13 (18): 1972-1977. ( PubMed , DOI )

  3. Qi, JH; Cheng, LH; Sun, YJ; Hirata, Y; Ushida, N; Ma, ZH; Osada, H; Nishikawa, T; Xiang, L: Identification of an Asexual Reproduction Inducer of Phytopathogenic and Toxigenic Fusarium ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2018.07; 57 (27): 8100-8104. ( PubMed , DOI )

  4. Zhang, H; Farooq, U; Cheng, LH; Ye, Y; Wang, YC; Kawagishi, H; Ojika, M; Qi, JH: Specific Inhibitors of Sporangium Formation of Phytophthora capsici from Kalimeris indica CHEMISTRY OF NATURAL COMPOUNDS. 2018.05; 54 (3): 567-569. ( DOI )

  1. Tomohiro Ishii, Koji Sato, Toshiyuki Kakumoto, Shigenori Miura, Kazushige Touhara, Shoji Takeuchi, Takao Nakata: Light generation of intracellular Ca(2+) signals by a genetically encoded protein BACCS. Nat Commun. 2015; 6 8021. ( PubMed , DOI )

  1. Toshiyuki Kakumoto, Takao Nakata: Optogenetic control of PIP3: PIP3 is sufficient to induce the actin-based active part of growth cones and is regulated via endocytosis. PLoS ONE. 2013; 8 (8): e70861. ( PubMed , DOI )

  1. Takao Nakata, Shinsuke Niwa, Yasushi Okada, Franck Perez, Nobutaka Hirokawa: Preferential binding of a kinesin-1 motor to GTP-tubulin-rich microtubules underlies polarized vesicle transport. J. Cell Biol.. 2011.07; 194 (2): 245-255. ( PubMed , DOI )

  1. Takao Nakata, Nobutaka Hirokawa: Neuronal polarity and the kinesin superfamily proteins. Sci. STKE. 2007.02; 2007 (372): pe6. ( PubMed , DOI )

  1. Junlin Teng, Tatemitsu Rai, Yosuke Tanaka, Yosuke Takei, Takao Nakata, Motoyuki Hirasawa, Ashok B Kulkarni, Nobutaka Hirokawa: The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium. Nat. Cell Biol.. 2005.05; 7 (5): 474-482. ( PubMed , DOI )

  1. Takao Nakata, Nobutaka Hirokawa: Microtubules provide directional cues for polarized axonal transport through interaction with kinesin motor head. J. Cell Biol.. 2003.09; 162 (6): 1045-1055. ( PubMed , DOI )

  2. Homma N, Takei Y, Tanaka Y, Nakata T, Terada S, Kikkawa M, Noda Y, Hirokawa N.: Kinesin superfamily protein 2A (KIF2A) functions in suppression of collateral branch extension Cell. 2003.07; 114 (2): 229-239. ( PubMed , DOI )

  1. Ying Xu, Sen Takeda, Takao Nakata, Yasuko Noda, Yosuke Tanaka, Nobutaka Hirokawa: Role of KIFC3 motor protein in Golgi positioning and integration. J. Cell Biol.. 2002.07; 158 (2): 293-303. ( PubMed , DOI )

  2. Kazuo Nakajima, Yosuke Takei, Yosuke Tanaka, Terunaga Nakagawa, Takao Nakata, Yasuko Noda, Mitsutoshi Setou, Nobutaka Hirokawa: Molecular motor KIF1C is not essential for mouse survival and motor-dependent retrograde Golgi apparatus-to-endoplasmic reticulum transport. Mol. Cell. Biol.. 2002.02; 22 (3): 866-873. ( PubMed )

  1. J Teng, Y Takei, A Harada, T Nakata, J Chen, N Hirokawa: Synergistic effects of MAP2 and MAP1B knockout in neuronal migration, dendritic outgrowth, and microtubule organization. J. Cell Biol.. 2001.10; 155 (1): 65-76. ( PubMed , DOI )

  2. Zhao C, Takita J, Tanaka Y, Setou M, Nakagawa T, Takeda S, Yang HW, Terada S, Nakata T, Takei Y, Saito M, Tsuji S, Hayashi Y, Hirokawa N.: Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta Cell. 2001.06; 105 (5): 587-597. ( PubMed , DOI )

  1. J Chen, T Nakata, Z Zhang, N Hirokawa: The C-terminal tail domain of neurofilament protein-H (NF-H) forms the crossbridges and regulates neurofilament bundle formation. J. Cell. Sci.. 2000.11; 113 Pt 21 3861-3869. ( PubMed )

  1. Nakata T, Terada S, Hirokawa N.: Visualization of the dynamics of synaptic vesicle and plasma membrane proteins in living axons Journal of Cell Biology. 1998.02; 140 (3): 659-674. ( PubMed , DOI )

  2. K i Nagata, A Puls, C Futter, P Aspenstrom, E Schaefer, T Nakata, N Hirokawa, A Hall: The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3. EMBO J.. 1998.01; 17 (1): 149-158. ( PubMed , DOI )

  1. H Yamazaki, T Nakata, Y Okada, N Hirokawa: Cloning and characterization of KAP3: a novel kinesin superfamily-associated protein of KIF3A/3B. Proc. Natl. Acad. Sci. U.S.A.. 1996.08; 93 (16): 8443-8448. ( PubMed )

  2. Terada S, Nakata T, Peterson AC, Hirokawa N.: Visualization of slow axonal transport in vivo Science. 1996.08; 273 (5276): 784-788. ( PubMed , DOI )

  3. R Takemura, T Nakata, Y Okada, H Yamazaki, Z Zhang, N Hirokawa: mRNA expression of KIF1A, KIF1B, KIF2, KIF3A, KIF3B, KIF4, KIF5, and cytoplasmic dynein during axonal regeneration. J. Neurosci.. 1996.01; 16 (1): 31-35. ( PubMed )

  1. T Nakata, N Hirokawa: Point mutation of adenosine triphosphate-binding motif generated rigor kinesin that selectively blocks anterograde lysosome membrane transport. J. Cell Biol.. 1995.11; 131 (4): 1039-1053. ( PubMed )

  2. H Yamazaki, T Nakata, Y Okada, N Hirokawa: KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport. J. Cell Biol.. 1995.09; 130 (6): 1387-1399. ( PubMed )

  1. M Kikkawa, T Ishikawa, T Nakata, T Wakabayashi, N Hirokawa: Direct visualization of the microtubule lattice seam both in vitro and in vivo. J. Cell Biol.. 1994.12; 127 (6 Pt 2): 1965-1971. ( PubMed )

  2. T Hayashi, F Soulie, T Nakata, N Hirokawa: Redistribution of synapsin I and synaptophysin in response to electrical stimulation in the rat neurohypophysial nerve endings. Cell Struct. Funct.. 1994.08; 19 (4): 253-262. ( PubMed )

  3. A Ando, K Yonezawa, I Gout, T Nakata, H Ueda, K Hara, Y Kitamura, Y Noda, T Takenawa, N Hirokawa: A complex of GRB2-dynamin binds to tyrosine-phosphorylated insulin receptor substrate-1 after insulin treatment. EMBO J.. 1994.07; 13 (13): 3033-3038. ( PubMed )

  4. S Kondo, R Sato-Yoshitake, Y Noda, H Aizawa, T Nakata, Y Matsuura, N Hirokawa: KIF3A is a new microtubule-based anterograde motor in the nerve axon. J. Cell Biol.. 1994.06; 125 (5): 1095-1107. ( PubMed )

  5. H Miki, K Miura, K Matuoka, T Nakata, N Hirokawa, S Orita, K Kaibuchi, Y Takai, T Takenawa: Association of Ash/Grb-2 with dynamin through the Src homology 3 domain. J. Biol. Chem.. 1994.02; 269 (8): 5489-5492. ( PubMed )

  1. T Nakata, R Sato-Yoshitake, Y Okada, Y Noda, N Hirokawa: Thermal drift is enough to drive a single microtubule along its axis even in the absence of motor proteins. Biophys. J.. 1993.12; 65 (6): 2504-2510. ( PubMed , DOI )

  2. Z Zhang, Y Tanaka, S Nonaka, H Aizawa, H Kawasaki, T Nakata, N Hirokawa: The primary structure of rat brain (cytoplasmic) dynein heavy chain, a cytoplasmic motor enzyme. Proc. Natl. Acad. Sci. U.S.A.. 1993.09; 90 (17): 7928-7932. ( PubMed )

  3. Y Noda, T Nakata, N Hirokawa: Localization of dynamin: widespread distribution in mature neurons and association with membranous organelles. Neuroscience. 1993.07; 55 (1): 113-127. ( PubMed )

  4. T Nakata, R Takemura, N Hirokawa: A novel member of the dynamin family of GTP-binding proteins is expressed specifically in the testis. J. Cell. Sci.. 1993.05; 105 ( Pt 1) 1-5. ( PubMed )

  5. T. Nakata and N. Hirokawa. : Is dynamin GTPase a microtubule based motor? Neuronal Cytoskeleton. 1993; 285-303.

  1. Y Tanaka, K Kawahata, T Nakata, N Hirokawa: Chronological expression of microtubule-associated proteins (MAPs) in EC cell P19 after neuronal induction by retinoic acid. Brain Res.. 1992.11; 596 (1-2): 269-278. ( PubMed )

  2. K Maeda, T Nakata, Y Noda, R Sato-Yoshitake, N Hirokawa: Interaction of dynamin with microtubules: its structure and GTPase activity investigated by using highly purified dynamin. Mol. Biol. Cell. 1992.10; 3 (10): 1181-1194. ( PubMed )

  3. T Nakata, N Hirokawa: Organization of cortical cytoskeleton of cultured chromaffin cells and involvement in secretion as revealed by quick-freeze, deep-etching, and double-label immunoelectron microscopy. J. Neurosci.. 1992.06; 12 (6): 2186-2197. ( PubMed )

  1. T Nakata, A Iwamoto, Y Noda, R Takemura, H Yoshikura, N Hirokawa: Predominant and developmentally regulated expression of dynamin in neurons. Neuron. 1991.09; 7 (3): 461-469. ( PubMed )

  1. T Nakata, K Sobue, N Hirokawa: Conformational change and localization of calpactin I complex involved in exocytosis as revealed by quick-freeze, deep-etch electron microscopy and immunocytochemistry. J. Cell Biol.. 1990.01; 110 (1): 13-25. ( PubMed )

  1. T Nakata, N Hirokawa: Cytoskeletal reorganization of human platelets after stimulation revealed by the quick-freeze deep-etch technique. J. Cell Biol.. 1987.10; 105 (4): 1771-1780. ( PubMed )

  1. 稲葉　弘哲, 中田　隆夫: 低分子量Gタンパク質の光遺伝学による操作と細胞内機能の観察 顕微鏡. 2021.08; 56 (2): 59-63. ( DOI )

  1. 豊島 学, 蒋 緒光, 小川 覚之, 大西 哲生, 吉原 壯悟, Balan Shabeesh, 廣川 信隆, 吉川 武男: カルボニルストレスによる神経発達異常のタンパク質分子病態解析 日本神経精神薬理学会年会・日本生物学的精神医学会年会・日本精神薬学会総会・学術集会合同年会プログラム・抄録集. 2020.08; 50回・42回・4回 190.

  1. 石井　智浩, 中田　隆夫: 光スイッチによる細胞内Ca2+シグナル制御 実験医学. 2016.03; 34 (4): 601-606.

  1. 中田隆夫: シグナル分子の光制御技術と神経の形態形成 ブレインサイエンス・レビュー2011(伊藤正男・川合述史編）. 2011.03; 23-36.

  1. 中田隆夫　: 東京医科歯科大学の教授就任にあたって　 解剖学雑誌 vol.84;26-27,2009. 2009; 84 26-27.

  1. 中田隆夫: 細胞内膜動態に関わる細胞骨格蛋白質について 解剖学雑誌. 1998.04; 73 (2): 107-110.

  1. Cheng, LH; Wang, YH; Xiang, L; Qi, JH: Heat Shock Cognate 70 kDa Protein Is the Target of Tetradecyl 2,3-Dihydroxybenzoate for Neuritogenic Effect in PC12 Cells BIOMEDICINES. 2021.10; 9 (10): 1483. ( PubMed , DOI )

  2. Cheng, LH; Osada, H; Xing, TY; Yoshida, M; Xiang, L; Qi, JH: The Insulin Receptor: A Potential Target of Amarogentin Isolated from Gentiana rigescens Franch That Induces Neurogenesis in PC12 Cells BIOMEDICINES. 2021.05; 9 (5): ( PubMed , DOI )

  3. Pan, YJ; Liu, YN; Fujii, R; Farooq, U; Cheng, LH; Matsuura, A; Qi, JH; Xiang, L: Ehretiquinone from Onosma bracteatum Wall Exhibits Antiaging Effect on Yeasts and Mammals through Antioxidative Stress and Autophagy Induction OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2021.01; 2021 1-15. ( PubMed , DOI )

  1. Disasa, D; Cheng, LH; Manzoor, M; Liu, Q; Wang, Y; Xiang, L; Qi, JH: Amarogentin from Gentiana rigescens Franch Exhibits Antiaging and Neuroprotective Effects through Antioxidative Stress OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2020.08; 2020 1-15. ( PubMed , DOI )

  2. Liu, Q; Cheng, LH; Matsuura, A; Xiang, L; Qi, JH: Gentiopicroside, a Secoiridoid Glycoside from Gentiana rigescens Franch, Extends the Lifespan of Yeast via Inducing Mitophagy and Antioxidative Stress OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2020.08; 2020 1-12. ( PubMed , DOI )

  3. 豊島学, 蒋緒光, 小川覚之, 大西哲生, 吉原壯悟, SHABEESH Balan, 廣川信隆, 吉川武男: カルボニルストレス性統合失調症の発症脆弱性に関わるCRMP2の機能異常 統合失調症研究. 2020; 10 (1):

  1. Cheng, LH; Muroi, M; Cao, SN; Bian, LL; Osada, H; Xiang, L; Qi, JH: 3β,23,28-Trihydroxy-12-oleanene 3β-Caffeate from Desmodium sambuense-Induced Neurogenesis in PC12 Cells Mediated by ER Stress and BDNF-TrkB Signaling Pathways MOLECULAR PHARMACEUTICS. 2019.04; 16 (4): 1423-1432. ( PubMed , DOI )

  1. Cheng, LH; Ye, Y; Xiang, L; Osada, H; Qi, JH: Lindersin B from Lindernia crustacea induces neuritogenesis by activation of tyrosine kinase A/phosphatidylinositol 3 kinase/extracellular signal-regulated kinase signaling pathway PHYTOMEDICINE. 2017.01; 24 31-38. ( PubMed , DOI )

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