Cellular Physiological Chemistry

71  articles.  
* There may be some overlapped articles listed due to the difference of format.

  1. Aiko Takada, Toshifumi Asano, Ken-Ichi Nakahama, Takashi Ono, Takao Nakata, Tomohiro Ishii: Development of an optogenetics tool, Opto-RANK, for control of osteoclast differentiation using blue light. Sci Rep. 2024.01; 14 (1): 1749. ( PubMed , DOI )

  1. Namangkalakul W, Nagai S, Jin C, Nakahama KI, Yoshimoto Y, Ueha S, Akiyoshi K, Matsushima K, Nakashima T, Takechi M, Iseki S: Augmented effect of fibroblast growth factor 18 in bone morphogenetic protein 2-induced calvarial bone healing by activation of CCL2/CCR2 axis on M2 macrophage polarization. Journal of tissue engineering. 2023.01; 14 20417314231187960. ( PubMed , DOI )

  1. Fujioka A, Nagano M, Ikegami K, Masumoto KH, Yoshikawa T, Koinuma S, Nakahama KI, Shigeyoshi Y: Circadian expression and specific localization of synaptotagmin17 in the suprachiasmatic nucleus, the master circadian oscillator in mammals. Brain research. 2022.11; 148129. ( PubMed , DOI )

  2. Hidaka S, Mouri Y, Akiyama M, Miyasaka N, Nakahama KI: GPR110, a receptor for synaptamide, expressed in osteoclasts negatively regulates osteoclastogenesis. Prostaglandins, leukotrienes, and essential fatty acids. 2022.06; 182 102457. ( PubMed , DOI )

  3. Kawatsura Risa, Hara Yusuke, Akiyama Masako, Tachikawa Noriko, Nakahama Ken-Ichi: Gap junctional intercellular communication attenuates osteoclastogenesis induced by activated osteoblasts BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2022.03; 597 71-76. ( PubMed , DOI )

  1. Nagashima S, Maruyama J, Honda K, Kondoh Y, Osada H, Nawa M, Nakahama KI, Ishigami-Yuasa M, Kagechika H, Sugimura H, Iwasa H, Arimoto-Matsuzaki K, Nishina H, Hata Y: CSE1L promotes nuclear accumulation of transcriptional coactivator TAZ and enhances invasiveness of human cancer cells. The Journal of biological chemistry. 2021.05; 297 (1): 100803. ( PubMed , DOI )

  2. LIU Hongding, AKIYAMA Masako, NAKAHAMA Ken‒ichi: Ogerin Accelerates Osteoclastogenesis via GPR68 in Neutral Conditions 口腔病学会雑誌. 2021.03; 88 (1): 58-66.

  3. Fukuda S, Akiyama M, Niki Y, Kawatsura R, Harada H, Nakahama KI: Inhibitory effects of miRNAs in astrocytes on C6 glioma progression via connexin 43. Molecular and cellular biochemistry. 2021.03; ( PubMed , DOI )

  1. Miki H, Okito A, Akiyama M, Ono T, Tachikawa N, Nakahama KI: Genetic and epigenetic regulation of osteopontin by cyclic adenosine 3' 5'-monophosphate in osteoblasts. Gene. 2020.08; (763): 145059. ( PubMed , DOI )

  1. Nagaoka N, Yoshida T, Cao K, Iwasaki Y, Nakahama KI, Morita I, Ohno-Matsui K: Visual arrestin modulates gene expression in the retinal pigment epithelium: Implications for homeostasis in the retina. Biochemistry and biophysics reports. 2019.12; 20 100680. ( PubMed , DOI )

  2. Hirayama J, Alifu Y, Hamabe R, Yamaguchi S, Tomita J, Maruyama Y, Asaoka Y, Nakahama KI, Tamaru T, Takamatsu K, Takamatsu N, Hattori A, Nishina S, Azuma N, Kawahara A, Kume K, Nishina H: The clock components Period2, Cryptochrome1a, and Cryptochrome2a function in establishing light-dependent behavioral rhythms and/or total activity levels in zebrafish. Scientific reports. 2019.01; 9 (1): 196. ( PubMed , DOI )

  1. Fukuda S, Akiyama M, Harada H, Nakahama KI: Effect of gap junction-mediated intercellular communication on TGF-β induced epithelial-to-mesenchymal transition. Biochemical and biophysical research communications. 2018.12; 508 (3): 928-933. ( PubMed , DOI )

  2. Oshima N., Nakahama K., Miyasaka N., Morita I.: TISSUE ENGINEERED LYMPHATIC MICROVESSELS USING CELL-PRINTING TECHNOLOGY INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER. 2018.09; 28 197.

  3. Nisha Gowri Manila, Atsushi Kaida, Ken-Ichi Nakahama, Masahiko Miura: Insulin-like growth factor I receptor regulates the radiation-induced G2/M checkpoint in HeLa cells. Biochem. Biophys. Res. Commun.. 2018.08; 503 (4): 2977-2987. ( PubMed , DOI )

  4. Charoenlarp, P, Rajendrana, AK, Fujihara, R, Kojima T, Nakahama K, Sasaki, Y, Akiyoshi K, Takechi M, Iseki S: The improvement of calvarial bone healing by durable nanogel-crosslinked materials Journal of Biomaterials Science, Polymer Edition. 2018.08; ( PubMed , DOI )

  5. Sato Takahiro, Akiyama Masako, Nakahama Ken-ichi, Seo Shujiro, Watanabe Masamichi, Tatsuzaki Jin, Morita Ikuo: ラッカセイ種皮エキスによる巨核球の血小板産生活性を刺激する新しい方法(A novel mode of stimulating platelet formation activity in megakaryocytes with peanut skin extract) Journal of Natural Medicines. 2018.01; 72 (1): 211-219. ( ichushi )

  1. Syun Nishihara, Mami Ikeda, Hitoshi Ozawa, Masako Akiyama, Satoshi Yamaguchi, Ken-Ichi Nakahama: Role of cAMP in phenotypic changes of osteoblasts. Biochem. Biophys. Res. Commun.. 2017.11; ( PubMed , DOI )

  2. Takahiro Sato, Masako Akiyama, Ken-Ichi Nakahama, Shujiro Seo, Masamichi Watanabe, Jin Tatsuzaki, Ikuo Morita: A novel mode of stimulating platelet formation activity in megakaryocytes with peanut skin extract. J Nat Med. 2017.10; ( PubMed , DOI )

  3. Ishida T, Yoshida T, Shinohara K1, Cao K, Nakahama K, Morita I, Ohno-Matsui K: Potential role of sirtuin 1 in Müller glial cells in mice choroidal neovascularization PLoS One. 2017.09; 12 (9): ( PubMed , DOI )

  4. Tsuyoshi Matsuura, Shizuko Ichinose, Masako Akiyama, Yuki Kasahara, Noriko Tachikawa, Ken-Ichi Nakahama: Involvement of CX3CL1 in the Migration of Osteoclast Precursors Across Osteoblast Layer Stimulated by Interleukin-1ß. J. Cell. Physiol.. 2017.07; 232 (7): 1739-1745. ( PubMed , DOI )

  5. Kosei Shinohara, Takeshi Yoshida, Hongding Liu, Shizuko Ichinose, Tomoka Ishida, Ken-Ichi Nakahama, Natsuko Nagaoka, Muka Moriyama, Ikuo Morita, Kyoko Ohno-Matsui: Establishment of novel therapy to reduce progression of myopia in rats with experimental myopia by fibroblast transplantation on sclera. J Tissue Eng Regen Med. 2017.04; ( PubMed , DOI )

  1. Asuka Okito, Ken-Ichi Nakahama, Masako Akiyama, Takashi Ono, Ikuo Morita: Involvement of the G-protein-coupled receptor 4 in RANKL expression by osteoblasts in an acidic environment. Biochem. Biophys. Res. Commun.. 2015.02; ( PubMed , DOI )

  1. Hashida Yukihiko, Nakahama Ken-ichi, Shimizu Kaori, Akiyama Masako, Harada Kiyoshi, Morita Ikuo: Communication-dependent mineralization of osteoblasts via gap junctions. Bone. 2014.04; 61 19-26. ( PubMed , DOI )

  2. Hatano Yu, Nakahama Ken-ichi, Isobe Mitsuaki, Morita Ikuo: Tumor associated osteoclast-like giant cells promote tumor growth and lymphangiogenesis by secreting vascular endothelial growth factor-C. Biochem Biophys Res Commun. 2014.03; 446 (1): 149-154. ( PubMed , DOI )

  3. Safronova Olga S, Nakahama Ken-Ichi, Morita Ikuo: Acute hypoxia affects P-TEFb through HDAC3 and HEXIM1-dependent mechanism to promote gene-specific transcriptional repression. Nucleic Acids Res. 2014; 42 (14): 8954-8969. ( PubMed , DOI )

  1. Akiyama M, Nakahama K, Morita I: Impact of Docosahexaenoic Acid on Gene Expression during Osteoclastogenesis in Vitro-A Comprehensive Analysis. Nutrients. 2013; 5 (8): 3151-3162. ( PubMed , DOI )

  1. Fujioka-Kobayashi Masako, Ota Masato S, Shimoda Asako, Nakahama Ken-ichi, Akiyoshi Kazunari, Miyamoto Youji, Iseki Sachiko: Cholesteryl group- and acryloyl group-bearing pullulan nanogel to deliver BMP2 and FGF18 for bone tissue engineering. Biomaterials. 2012.10; 33 (30): 7613-7620. ( PubMed , DOI )

  2. Li X, Akiyama M, Nakahama K, Koshiishi T, Takeda S, Morita I: Role of intercellular adhesion molecule-2 in osteoclastogenesis. Genes Cells. 2012.07; 17 (7): 568-575. ( PubMed , DOI )

  3. Wayakanon Praween, Bhattacharjee Rajib, Nakahama Ken-ichi, Morita Ikuo: The role of the Cx43 C-terminus in GJ plaque formation and internalization. Biochem Biophys Res Commun. 2012.04; 420 (2): 456-461. ( PubMed , DOI )

  1. Aoi Yoko, Nakahama Ken-ichi, Morita Ikuo, Safronova Olga: The involvement of DNA and histone methylation in the repression of IL-1beta-induced MCP-1 production by hypoxia. Biochem Biophys Res Commun. 2011.10; 414 (1): 252-258. ( PubMed , DOI )

  2. Tsugawa Junichi, Komaki Motohiro, Yoshida Tomoko, Nakahama Ken-ichi, Amagasa Teruo, Morita Ikuo: Cell-printing and transfer technology applications for bone defects in mice. J Tissue Eng Regen Med. 2011.10; 5 (9): 695-703. ( PubMed , DOI )

  3. Wang Jiying, Ohno-Matsui Kyoko, Nakahama Ken-ichi, Okamoto Aikou, Yoshida Takeshi, Shimada Noriaki, Mochizuki Manabu, Morita Ikuo: Amyloid beta enhances migration of endothelial progenitor cells by upregulating CX3CR1 in response to fractalkine, which may be associated with development of choroidal neovascularization. Arterioscler Thromb Vasc Biol. 2011.07; 31 (7): e11-e18. ( PubMed , DOI )

  1. Nakahama Ken-Ichi: Cellular communications in bone homeostasis and repair. Cell Mol Life Sci. 2010.12; 67 (23): 4001-4009. ( PubMed , DOI )

  2. Yuan J, Akiyama M, Nakahama K, Sato T, Uematsu H, Morita I: The effects of polyunsaturated fatty acids and their metabolites on osteoclastogenesis in vitro. Prostaglandins Other Lipid Mediat. 2010.06; 92 (1-4): 85-90. ( PubMed , DOI )

  3. Akahori Taichi, Kobayashi Akiko, Komaki Motohiro, Hattori Hideshi, Nakahama Ken-Ichi, Ichinose Shizuko, Abe Mayumi, Takeda Satoru, Morita Ikuo: Implantation of capillary structure engineered by optical lithography improves hind limb ischemia in mice. Tissue Eng Part A. 2010.03; 16 (3): 953-959. ( PubMed , DOI )

  4. Nakahama K.: Cellular communications in bone homeostasis and repair.(Review). Cell Mol Life Sci.. 2010; 67 (23): 4001-9.

  1. Obitsu S, Ahmed N, Nishitsuji H, Hasegawa A, Nakahama K, Morita I, Nishigaki K, Hayashi T, Masuda T, Kannagi M: Potential enhancement of osteoclastogenesis by severe acute respiratory syndrome coronavirus 3a/X1 protein Arch Virol. 2009; 154 (9): 1457-1464. ( PubMed , DOI )

  2. Safronova O, Pluemsampant S, Nakahama K, Morita I: Regulation of chemokine gene expression by hypoxia via cooperative activation of NF-kappaB and histone deacetylase Int J Biochem Cell Biol. 2009; 41 (11): 2270-2280. ( PubMed , DOI )

  3. Tsuchiya T, Nakahama K, Asakawa Y, Maemura T, Tanaka M, Takeda S, Morita M, Morita I: The reduction in pigment epithelium-derived factor is a sign of malignancy in ovarian cancer expressing low-level of vascular endothelial growth factor Gynecol Endocrinol. 2009; 25 (2): 104-109. ( PubMed , DOI )

  4. Bhattacharjee R, Kaneda M, Nakahama K, Morita I: The steady-state expression of connexin43 is maintained by the PI3K/Akt in osteoblasts Biochem Biophys Res Commun. 2009; 382 (2): 440-444. ( PubMed , DOI )

  5. Kaneda M, Nomura SM, Ichinose S, Kondo S, Nakahama K, Akiyoshi K, Morita I.: Direct formation of proteo-liposomes by in vitro synthesis and cellular cytosolic delivery with connexin-expressing liposomes. Biomaterials. 2009; 23-24 3971-7.

  1. Wang J, Ohno-Matsui K, Yoshida T, Kojima A, Shimada N, Nakahama K, Safranova O, Iwata N, Saido TC, Mochizuki M, Morita I: Altered function of factor I caused by amyloid beta: implication for pathogenesis of age-related macular degeneration from Drusen. J Immunol. 2008.07; 181 (1): 712-720. ( PubMed )

  2. Ariko Kojima, Ken-Ichi Nakahama, Kyoko Ohno-Matsui, Noriaki Shimada, Keisuke Mori, Sachiko Iseki, Tetsuji Sato, Manabu Mochizuki, Ikuo Morita: Connexin 43 contributes to differentiation of retinal pigment epithelial cells via cyclic AMP signaling. Biochem. Biophys. Res. Commun.. 2008.02; 366 (2): 532-538. ( PubMed , DOI )

  3. Pluemsampant S, Safronova OS, Nakahama K, Morita I: Protein kinase CK2 is a key activator of histone deacetylase in hypoxia-associated tumors Int J Cancer. 2008; 122 (2): 333-341. ( PubMed , DOI )

  4. Hayashi H, Nakahama K, Sato T, Tuchiya T, Asakawa Y, Maemura T, Tanaka M, Morita M, Morita I: The role of Mac-1 (CD11b/CD18) in osteoclast differentiation induced by receptor activator of nuclear factor-kappaB ligand FEBS Lett. 2008; 582 (21-22): 3243-3248. ( PubMed , DOI )

  5. Kaneda M, Zhang D, Bhattacharjee R, Nakahama K, Arii S, Morita I: Vitamin K2 suppresses malignancy of HuH7 hepatoma cells via inhibition of connexin 43 Cancer Lett. 2008; 263 (1): 53-60. ( PubMed , DOI )

  1. Zhang D, Kaneda M, Nakahama K, Arii S, Morita I: Connexin 43 expression promotes malignancy of HuH7 hepatocellular carcinoma cells via the inhibition of cell-cell communication Cancer Lett. 2007; 252 (2): 208-215. ( PubMed , DOI )

  2. Chen BK, Huang CC, Chang WC, Chen YJ, Kikkawa U, Nakahama K, Morita I, Chang WC: PP2B-mediated dephosphorylation of c-Jun C terminus regulates phorbol ester-induced c-Jun/Sp1 interaction in A431 cells Mol Biol Cell. 2007; 18 (3): 1118-1127. ( PubMed , DOI )

  3. Zhao C, Fujinaga R, Tanaka M, Yanai A, Nakahama K, Shinoda K: Region-specific expression and sex-steroidal regulation on aromatase and its mRNA in the male rat brain: immunohistochemical and in situ hybridization analyses J Comp Neurol. 2007; 500 (3): 557-573. ( PubMed , DOI )

  4. Kobayashi A, Miyake H, Hattori H, Kuwana R, Hiruma Y, Nakahama K, Ichinose S, Ota M, Nakamura M, Takeda S, Morita I: In vitro formation of capillary networks using optical lithographic techniques Biochem Biophys Res Commun. 2007; 358 (3): 692-697. ( PubMed , DOI )

  5. Techawattanawisal W, Nakahama K, Komaki M, Abe M, Takagi Y, Morita I: Isolation of multipotent stem cells from adult rat periodontal ligament by neurosphere-forming culture system Biochem Biophys Res Commun. 2007; 357 (4): 917-923. ( PubMed , DOI )

  6. Kakehi S, Nakahama K, Morita I: Expression and possible role of PVR/CD155/Necl-5 in osteoclastogenesis Mol Cell Biochem. 2007; 301 (1-2): 209-217. ( PubMed , DOI )

  1. Kojima T, Nakahama K, Yamamoto K, Uematsu H, Morita I: Age- and cell cycle-dependent changes in EPC-1/PEDF promoter activity in human diploid fibroblast-like (HDF) cells Mol Cell Biochem. 2006; 293 (1-2): 63-69. ( PubMed , DOI )

  2. Hong J, Yokomakura A, Nakano Y, Ishihara K, Kaneda M, Onodera M, Nakahama K, Morita I, Niikura K, Ahn JW, Zee O, Ohuchi K: Inhibition of vacuolar-type (H+)-ATPase by the cytostatic macrolide apicularen A and its role in apicularen A-induced apoptosis in RAW 264.7 cells FEBS Lett. 2006; 580 (11): 2723-2730. ( PubMed , DOI )

  3. Yoshimura H, Nakahama K, Safronova O, Tanaka N, Muneta T, Morita I: Transforming growth factor-beta stimulates IL-1beta-induced monocyte chemoattractant protein-1 expression in human synovial cells via the ERK/AP-1 pathway Inflamm Res. 2006; 55 (12): 543-549. ( PubMed , DOI )

  1. Ohno-Matsui K, Ichinose S, Nakahama K, Yoshida T, Kojima A, Mochizuki M, Morita I: The effects of amniotic membrane on retinal pigment epithelial cell differentiation. Mol Vis. 2005.01; 11 1-10. ( PubMed )

  1. Iwasaki T, Nakahama K, Nagano M, Fujioka A, Ohyanagi H, Shigeyoshi Y: A partial hepatectomy results in altered expression of clock-related and cyclic glyceraldehyde 3-phosphate dehydrogenase (GAPDH) genes Life Sci. 2004; 74 (25): 3093-3102. ( PubMed , DOI )

  2. Hiruma Y, Nakahama K, Fujita H, Morita I: Vitamin K2 and geranylgeraniol, its side chain component, inhibited osteoclast formation in a different manner Biochem Biophys Res Commun. 2004; 314 (1): 24-30. ( PubMed )

  3. Fujinaga R, Kawano J, Matsuzaki Y, Kamei K, Yanai A, Sheng Z, Tanaka M, Nakahama K, Nagano M, Shinoda K: Neuroanatomical distribution of Huntingtin-associated protein 1-mRNA in the male mouse brain J Comp Neurol. 2004; 478 (1): 88-109. ( PubMed , DOI )

  4. Onodera M, Horiuchi Y, Nakahama K, Muneta T, Mano Y, Morita I: Induction of cyclooxygenase-1 in cultured synovial cells isolated from rheumatoid arthritis patients Inflamm Res. 2004; 53 (6): 217-222. ( PubMed , DOI )

  1. Uetama T, Ohno-Matsui K, Nakahama K, Morita I, Mochizuki M: Phenotypic change regulates monocyte chemoattractant protein-1 (MCP-1) gene expression in human retinal pigment epithelial cells. J Cell Physiol. 2003.10; 197 (1): 77-85. ( PubMed , DOI )

  2. Satoh S, Matsumura H, Nakajima T, Nakahama K, Kanbayashi T, Nishino S, Yoneda H, Shigeyoshi Y: Inhibition of rostral basal forebrain neurons promotes wakefulness and induces FOS in orexin neurons Eur J Neurosci. 2003; 17 (8): 1635-1645. ( PubMed )

  3. Safronova O, Nakahama K, Onodera M, Muneta T, Morita I: Effect of hypoxia on monocyte chemotactic protein-1 (MCP-1) gene expression induced by Interleukin-1beta in human synovial fibroblasts Inflamm Res. 2003; 52 (11): 480-486. ( PubMed , DOI )

  4. Masumoto KH, Fujioka A, Nakahama K, Inouye ST, Shigeyoshi Y: Effect of phosphodiesterase type 4 on circadian clock gene Per1 transcription Biochem Biophys Res Commun. 2003; 306 (3): 781-785. ( PubMed )

  5. Nagano M, Adachi A, Nakahama K, Nakamura T, Tamada M, Meyer-Bernstein E, Sehgal A, Shigeyoshi Y: An abrupt shift in the day/night cycle causes desynchrony in the mammalian circadian center J Neurosci. 2003; 23 (14): 6141-6151. ( PubMed )

  1. Ueda HR, Chen W, Adachi A, Wakamatsu H, Hayashi S, Takasugi T, Nagano M, Nakahama K, Suzuki Y, Sugano S, Iino M, Shigeyoshi Y, Hashimoto S: A transcription factor response element for gene expression during circadian night Nature. 2002; 418 (6897): 534-539. ( PubMed , DOI )

  2. Nakahama K, Fujioka A, Nagano M, Satoh S, Furukawa K, Sasaki H, Shigeyoshi Y: A role of the C-terminus of aquaporin 4 in its membrane expression in cultured astrocytes Genes Cells. 2002; 7 (7): 731-741. ( PubMed )

  1. Nakahama K, Nagano M, Fujioka A, Shinoda K, Sasaki H: Effect of TPA on aquaporin 4 mRNA expression in cultured rat astrocytes Glia. 1999; 25 (3): 240-246. ( PubMed )

  1. Sato T, Morita I, Sakaguchi K, Nakahama KI, Smith WL, Dewitt DL, Murota SI: Involvement of prostaglandin endoperoxide H synthase-2 in osteoclast-like cell formation induced by interleukin-1 beta J Bone Miner Res. 1996; 11 (3): 392-400. ( PubMed )

  1. Sato T, Morita I, Sakaguchi K, Nakahama K, Murota S: Involvement of cyclooxygenase-2 in bone loss induced by interleukin-1 beta Adv Prostaglandin Thromboxane Leukot Res. 1995; 23 445-447. ( PubMed )

  1. Nakahama K, Morita I, Murota S: Effects of endogenously produced arachidonic acid metabolites on rat mesangial cell proliferation Prostaglandins Leukot Essent Fatty Acids. 1994; 51 (3): 177-182. ( PubMed )

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