Personnel Information

写真a

LIANG Minggao


Job title

Junior Associate Professor

Research Areas, Keywords

Genetics, Genomics, Genome Biology, Epigenetics, Bioinformatics
To the head of this page.▲

Graduate School 【 display / non-display 】

  • University of Toronto, Molecular Genetics, Doctor's Course, 2021.04, Completed

To the head of this page.▲

Campus Career 【 display / non-display 】

  • 2024.08
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Advanced Therapeutic Sciences， Comprehensive Pathology， Junior Associate Professor
To the head of this page.▲
 

Published Papers & Misc 【 display / non-display 】

  1. Adele R, Hussein R, Tavares E, Ahmed K, Di Scipio M, Charish J, Liang M, Monis S, Tumber A, Chen X, Paton TA, Roslin NM, Eileen C, Ivakine E, Sunny NE, Wilson MD, Campos E, Rajala RV, Maynes JT, Monnier PP, Paterson AD, Héon E, Vincent A. Autosomal dominant macular dystrophy linked to a chromosome 17 tandem duplication. JCI insight. 2024.10; ( PubMed, DOI )

  2. Smith RJ, Liang M, Loe AKH, Yung T, Kim JE, Hudson M, Wilson MD, Kim TH. Epigenetic control of cellular crosstalk defines gastrointestinal organ fate and function. Nature communications. 2023.01; 14 (1): 497. ( PubMed, DOI )

  3. Langille E, Al-Zahrani KN, Ma Z, Liang M, Uuskula-Reimand L, Espin R, Teng K, Malik A, Bergholtz H, Ghamrasni SE, Afiuni-Zadeh S, Tsai R, Alvi S, Elia A, Lü Y, Oh RH, Kozma KJ, Trcka D, Narimatsu M, Liu JC, Nguyen T, Barutcu S, Loganathan SK, Bremner R, Bader GD, Egan SE, Cescon DW, Sørlie T, Wrana JL, Jackson HW, Wilson MD, Witkiewicz AK, Knudsen ES, Pujana MA, Wahl GM, Schramek D. Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer. Cancer discovery. 2022.12; 12 (12): 2930-2953. ( PubMed, DOI )

  4. Yanchus C, Drucker KL, Kollmeyer TM, Tsai R, Winick-Ng W, Liang M, Malik A, Pawling J, De Lorenzo SB, Ali A, Decker PA, Kosel ML, Panda A, Al-Zahrani KN, Jiang L, Browning JWL, Lowden C, Geuenich M, Hernandez JJ, Gosio JT, Ahmed M, Loganathan SK, Berman J, Trcka D, Michealraj KA, Fortin J, Carson B, Hollingsworth EW, Jacinto S, Mazrooei P, Zhou L, Elia A, Lupien M, He HH, Murphy DJ, Wang L, Abyzov A, Dennis JW, Maass PG, Campbell K, Wilson MD, Lachance DH, Wrensch M, Wiencke J, Mak T, Pennacchio LA, Dickel DE, Visel A, Wrana J, Taylor MD, Zadeh G, Dirks P, Eckel-Passow JE, Attisano L, Pombo A, Ida CM, Kvon EZ, Jenkins RB, Schramek D. A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation. Science (New York, N.Y.). 2022.10; 378 (6615): 68-78. ( PubMed, DOI )

  5. Marwaha AK, Laxer R, Liang M, Muise AM, Eiwegger T, IMMUNE DYSREGULATION GROUP. A Chromosomal Duplication Encompassing Interleukin-33 Causes a Novel Hyper IgE Phenotype Characterized by Eosinophilic Esophagitis and Generalized Autoimmunity. Gastroenterology. 2022.08; 163 (2): 510-513.e3. ( PubMed, DOI )

  6. Alizada A, Khyzha N, Wang L, Antounians L, Chen X, Khor M, Liang M, Rathnakumar K, Weirauch MT, Medina-Rivera A, Fish JE, Wilson MD. Conserved regulatory logic at accessible and inaccessible chromatin during the acute inflammatory response in mammals. Nature communications. 2021.01; 12 (1): 567. ( PubMed, DOI )

  7. Ahmed A, Liang M, Chi L, Zhou YQ, Sled JG, Wilson MD, Delgado-Olguín P. Maternal obesity persistently alters cardiac progenitor gene expression and programs adult-onset heart disease susceptibility. Molecular metabolism. 2021.01; 43 101116. ( PubMed, DOI )

  8. Liang M, Soomro A, Tasneem S, Abatti LE, Alizada A, Yuan X, Uusküla-Reimand L, Antounians L, Alvi SA, Paterson AD, Rivard GÉ, Scott IC, Mitchell JA, Hayward CPM, Wilson MD. Enhancer-gene rewiring in the pathogenesis of Quebec platelet disorder. Blood. 2020.12; 136 (23): 2679-2690. ( PubMed, DOI )

  9. Brunet JG, Sharma T, Tasneem S, Liang M, Wilson MD, Rivard GE, Hayward CPM. Thrombin generation abnormalities in Quebec platelet disorder. International journal of laboratory hematology. 2020.12; 42 (6): 801-809. ( PubMed, DOI )

  10. Zhu H, Uusküla-Reimand L, Isaev K, Wadi L, Alizada A, Shuai S, Huang V, Aduluso-Nwaobasi D, Paczkowska M, Abd-Rabbo D, Ocsenas O, Liang M, Thompson JD, Li Y, Ruan L, Krassowski M, Dzneladze I, Simpson JT, Lupien M, Stein LD, Boutros PC, Wilson MD, Reimand J. Candidate Cancer Driver Mutations in Distal Regulatory Elements and Long-Range Chromatin Interaction Networks. Molecular cell. 2020.03; 77 (6): 1307-1321.e10. ( PubMed, DOI )

  11. Tavares, E; Tang, C; Paterson, A; Li, S; Liang, M; Wilson, M; Campos, E; Vincent, A; Héon, E. Differential expression analysis suggests lipid metabolism plays a role in North Carolina Macular Dystrophy EUROPEAN JOURNAL OF HUMAN GENETICS. 2019.10; 27 1232.

  12. Yung T, Poon F, Liang M, Coquenlorge S, McGaugh EC, Hui CC, Wilson MD, Nostro MC, Kim TH. Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals. Nature communications. 2019.10; 10 (1): 4647. ( PubMed, DOI )

  13. Barbé L, Lanni S, López-Castel A, Franck S, Spits C, Keymolen K, Seneca S, Tomé S, Miron I, Letourneau J, Liang M, Choufani S, Weksberg R, Wilson MD, Sedlacek Z, Gagnon C, Musova Z, Chitayat D, Shannon P, Mathieu J, Sermon K, Pearson CE. CpG Methylation, a Parent-of-Origin Effect for Maternal-Biased Transmission of Congenital Myotonic Dystrophy. American journal of human genetics. 2017.03; 100 (3): 488-505. ( PubMed, DOI )

  14. Hayward CP, Liang M, Tasneem S, Soomro A, Waye JS, Paterson AD, Rivard GE, Wilson MD. The duplication mutation of Quebec platelet disorder dysregulates PLAU, but not C10orf55, selectively increasing production of normal PLAU transcripts by megakaryocytes but not granulocytes. PloS one. 2017; 12 (3): e0173991. ( PubMed, DOI )

  15. Uusküla-Reimand L, Hou H, Samavarchi-Tehrani P, Rudan MV, Liang M, Medina-Rivera A, Mohammed H, Schmidt D, Schwalie P, Young EJ, Reimand J, Hadjur S, Gingras AC, Wilson MD. Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders. Genome biology. 2016.08; 17 (1): 182. ( PubMed, DOI )

  16. Gonorazky H, Liang M, Cummings B, Lek M, Micallef J, Hawkins C, Basran R, Cohn R, Wilson MD, MacArthur D, Marshall CR, Ray PN, Dowling JJ. RNAseq analysis for the diagnosis of muscular dystrophy. Annals of clinical and translational neurology. 2016.01; 3 (1): 55-60. ( PubMed, DOI )

  17. Li Y, Liang M, Zhang Z. Regression analysis of combined gene expression regulation in acute myeloid leukemia. PLoS computational biology. 2014.10; 10 (10): e1003908. ( PubMed, DOI )

  18. Shahinas D, Liang M, Datti A, Pillai DR. A repurposing strategy identifies novel synergistic inhibitors of Plasmodium falciparum heat shock protein 90. Journal of medicinal chemistry. 2010.05; 53 (9): 3552-7. ( PubMed, DOI )

▼display all

To the head of this page.▲