Personnel Information

写真a

NAGATA MASAHIRO


Job title

Assistant Professor

Campus Career 【 display / non-display

  • 2024.06
     
     
    Tokyo Medical and Dental University, Medical Research Institute, Division of Visionary Life Science, Department of Medical Chemistry, Visiting Lecturer
  • 2024.07
    -
    2024.08
    Tokyo Medical and Dental University, Medical Research Institute, Division of Visionary Life Science, Department of Medical Chemistry, Visiting Lecturer
  • 2024.09
     
     
    Tokyo Medical and Dental University, Medical Research Institute, Division of Visionary Life Science, Department of Medical Chemistry, Assistant Professor
  • 2024.10
    -
    Now
    Institute of Science Tokyo, -, Institute of Integrated Research, -, Department of Medical Chemistry, Assistant Professor
 

Published Papers & Misc 【 display / non-display

  1. A shorter splicing isoform antagonizes ZBP1 to modulate cell death and inflammatory responses. The EMBO journal. 2025.04;

  2. ADAR1 averts fatal type I interferon induction by ZBP1. Nature. 2022.07;

  3. Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors. The Journal of experimental medicine. 2021.01;

  4. Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation. Nature communications. 2020.04;

  5. Mincle: 20 years of a versatile sensor of insults. International immunology. 2018.05;

  6. Lipidated Brartemicin Analogues Are Potent Th1-Stimulating Vaccine Adjuvants. Journal of medicinal chemistry. 2018.02;

  7. Intracellular metabolite β-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity. Proceedings of the National Academy of Sciences of the United States of America. 2017.04;

  8. Lipid structure influences the ability of glucose monocorynomycolate to signal through Mincle. Organic & biomolecular chemistry . 2016.10;

  9. Total synthesis of a cyclopropane-fatty acid α-glucosyl diglyceride from Lactobacillus plantarum and identification of its ability to signal through Mincle. Chemical communications (Cambridge, England). 2016.09;

  10. Pathogen-sensing by mincle: Function and molecular aspects C-Type Lectin Receptors in Immunity. 2016.01;

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Conference Activities & Talks 【 display / non-display

  1. Gasdermin-independent release of IL-1 family cytokines drives skin inflammation induced by Caspase-8 dependent keratinocyte death. 2025.06.20

  2. Regulation of non-infectious interferon produced by self nucleic acid. 2025.05.22

  3. Masahiro NAGATA. IL-1 family cytokines cause skin inflammation induced by Caspase-8 dependent keratinocyte death independently of gasdermins. Cell Death and Innate Immunity 2025.05.13 Suzhou, China