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SUGAHARA Osamu
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Campus Career 【 display / non-display 】
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2024.04-2024.09Tokyo Medical and Dental University, TMDU Advanced Research Institute (TMDU-ARIS), , -, Project Assistant Professor
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2024.10-NowInstitute of Science Tokyo, -, Institute of Integrated Research, -, Anticancer Strategies Laboratory, Project Assistant Professor
Academic Society Affiliations 【 display / non-display 】
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The Molecular Biology Society of Japan
Published Papers & Misc 【 display / non-display 】
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Osamu Sugahara, Daisuke Koga, Takeru Oka, Shigeaki Sugiyama, Reona Wada, Tsunaki Higa, Keiichi I. Nakayama. Antitumor Activity of Tumor-Infiltrating Neutrophils Revealed by a Syngeneic Mouse Model of Cholangiocarcinoma Cancer Science. 2025.07; ( DOI )
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Mizoo Taisuke, Oka Takeru, Sugahara Osamu, Minato Takafumi, Higa Tsunaki, Nakayama Keiichi I.. GPLD1+ cancer stem cells contribute to chemotherapy resistance and tumour relapse in intestinal cancer(タイトル和訳中) The Journal of Biochemistry. 2025.02; 177 (2): 105-119. ( ichushi )
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Matsumoto Kazuhide, Fujimori Nao, Ichihara Kazuya, Takeno Ayumu, Murakami Masatoshi, Ohno Akihisa, Kakehashi Shotaro, Teramatsu Katsuhito, Ueda Keijiro, Nakata Kohei, Sugahara Osamu, Yamamoto Takeo, Matsumoto Akinobu, Nakayama Keiichi I., Oda Yoshinao, Nakamura Masafumi, Ogawa Yoshihiro. 膵管腺癌の患者由来オルガノイドによるサブタイプの判定と臨床転帰予測(Patient-derived organoids of pancreatic ductal adenocarcinoma for subtype determination and clinical outcome prediction) Journal of Gastroenterology. 2024.07; 59 (7): 629-640. ( ichushi )
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Funasaki S, Hatano A, Nakatsumi H, Koga D, Sugahara O, Yumimoto K, Baba M, Matsumoto M, Nakayama KI. A stepwise and digital pattern of RSK phosphorylation determines the outcome of thymic selection. iScience. 2023.09; 26 (9): 107552. ( PubMed, DOI )
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Kodama M, Toyokawa G, Sugahara O, Sugiyama S, Haratake N, Yamada Y, Wada R, Takamori S, Shimokawa M, Takenaka T, Tagawa T, Kittaka H, Tsuruda T, Tanaka K, Komatsu Y, Nakata K, Imado Y, Yamazaki K, Okamoto I, Oda Y, Takahashi M, Izumi Y, Bamba T, Shimizu H, Yoshizumi T, Nakayama KI. Modulation of host glutamine anabolism enhances the sensitivity of small cell lung cancer to chemotherapy. Cell reports. 2023.08; 42 (8): 112899. ( PubMed, DOI )
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Takeru Oka, Tsunaki Higa, Osamu Sugahara, Daisuke Koga, Shogo Nakayama, Keiichi I. Nakayama. Ablation of p57+ Quiescent Cancer Stem Cells Suppresses Recurrence after Chemotherapy of Intestinal Tumors CANCER RESEARCH. 2023.05; 83 (9): 1393-1409. ( PubMed, DOI )
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Tsunaki Higa, Yasutaka Okita, Akinobu Matsumoto, Shogo Nakayama, Takeru Oka, Osamu Sugahara, Daisuke Koga, Shoichiro Takeishi, Hirokazu Nakatsumi, Naoki Hosen, Sylvie Robine, Makoto M. Taketo, Toshiro Sato & Keiichi I. Nakayama. Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium Nature Communications. 2022.03; 13 ( PubMed, DOI )