Graduating School 【 display / non-display 】
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The University of Tokyo, 2013, Graduated
Graduate School 【 display / non-display 】
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The University of Tokyo, Doctor's Course, 2018, Completed
Campus Career 【 display / non-display 】
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2024.02-2024.09Tokyo Medical and Dental University， Institute of Biomaterials and Bioengineering， -， -， Assistant Professor
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2024.10-NowInstitute of Science Tokyo， -， Institute of Integrated Research， Division of Biomedical Materials， Department of Organic Biomaterials， Assistant Professor
Published Papers & Misc 【 display / non-display 】
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Mao Hori, Angela Steinauer, Stephan Tetter, Jamiro Hälg, Eva-Maria Manz, Donald Hilvert. Stimulus-responsive assembly of nonviral nucleocapsids. Nature Communications. 2024.04; 15 (1): 3576. ( PubMed, DOI )
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Mao Hori, Nan Qiao, Kohki Yamada, Jongmin Yum, Satomi Ogura, Satoshi Uchida, Hyun Jin Kim, Mitsuru Naito, Kanjiro Miyata. Formulation-Driven Control of mRNA Polyplex Physicochemical Properties Enables Spleen-Targeted Systemic Delivery ACS Applied Bio Materials. 2026.03; ( DOI )
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Nan Qiao, Mao Hori, Mitsuru Naito, Heemin Chang, Satomi Ogura, Mika Suzuki, Tsuyoshi Kimura, Shigeto Fukushima, Hyun Jin Kim, Satoshi Uchida, Kanjiro Miyata. Increasing polycation hydrophobicity in mRNA polyplex vaccines enhances the efficacy of humoral and cellular immunity induction Biomaterials. 2026.01; 324 123515. ( DOI )
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Heemin Chang, Fadlina Aulia, Rimpei Kamegawa, Nan Qiao, Mao Hori, Satomi Ogura, Chun Yin Jerry Lau, Naoki Yamada, Kaori Taniwaki, Mitsuru Naito, Hyun Jin Kim, Kanjiro Miyata. Silica-coated polyion complexes for enhanced pulmonary messenger RNA delivery with optimized silica layer stability Journal of Controlled Release. 2025.08;
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Yukine Ishibashi, Mitsuru Naito, Yusuke Watanuki, Mao Hori, Satomi Ogura, Kaori Taniwaki, Masaru Cho, Ryosuke Komiya, Yuki Mochida, Kanjiro Miyata. Size-Dependent Glioblastoma Targeting by Polymeric Nanoruler with Prolonged Blood Circulation. Bioconjug Chem. 2024.08; 35 (8): 1154-1159. ( PubMed, DOI )
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Miki Suzuki, Yuki Mochida, Mao Hori, Akimasa Hayashi, Kazuko Toh, Theofilus A. Tockary, Xueying Liu, Victor Marx, Hidetomo Yokoo, Kanjiro Miyata, Makoto Oba, Satoshi Uchida. Poly(ethylene Glycol) (PEG)–OligoRNA Hybridization to mRNA Enables Fine-Tuned Polyplex PEGylation for Spleen-Targeted mRNA Delivery Small Science. 2024.04; 4 (4): 2300258.
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Dalia Dranseike, Yusuke Ota, Thomas G W Edwardson, Elia A Guzzi, Mao Hori, Zrinka Raguz Nakic, Dhananjay V Deshmukh, Mikail D Levasseur, Kevin Mattli, Christina M Tringides, Jiangtao Zhou, Donald Hilvert, Christin Peters, Mark W Tibbitt. Designed modular protein hydrogels for biofabrication. Acta Biomater. 2024.03; 177 107-117. ( PubMed, DOI )
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Jongmin Yum, Fadlina Aulia, Keisuke Kamiya, Mao Hori, Nan Qiao, Beob Soo Kim, Mitsuru Naito, Satomi Ogura, Tetsuya Nagata, Takanori Yokota, Satoshi Uchida, Satoshi Obika, Hyun Jin Kim, Kanjiro Miyata. Hydrophobicity Tuning of Cationic Polyaspartamide Derivatives for Enhanced Antisense Oligonucleotide Delivery. Bioconjug Chem. 2024.02; 35 (2): 125-131. ( PubMed, DOI )
Books etc 【 display / non-display 】
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Mitsuru Naito, Mao Hori. Drug Delivery Systems for Musculoskeletal Tissues. Springer, Cham， 2024.03 Drug Delivery Systems for Muscles (ISBN : 978-3-031-55652-4)
Conference Activities & Talks 【 display / non-display 】
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Mao Hori. Enzyme-Triggered Assembly of Nonviral Nucleocapsids. Frontiers 2026 2026.01.14 EPFL, Lausanne, Switzerland
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堀真緒. 人工ペプチド・タンパク質を基盤としたmRNA送達システムの開発. 令和7年度再生・細胞医療・遺伝子治療プロジェクト研究交流会 2025.11.13
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堀真緒, 濱田萌花, 小倉里美, 滝口美沙希, 松元亮. 酵素反応を利用したRNA内包タンパク質ケージの自己組織化機構の制御と理解. 第20回 ナノ・バイオメディカル学会大会 2025.10.23
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Mao Hori. Self-Assembly Around RNA: From Mechanistic Insights to Applications. 27th iCeMS International Symposium 2025.10.02
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堀真緒. Enzyme-triggered formation of protein cages encapsulating RNAs. ナノ学会 ナノ構造物性・ナノ機能応用両部会合同シンポジウム 2024.11.08