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経歴(学外) 【 表示 ／ 非表示 】
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2011年04月-2012年03月日本学術振興会 特別研究員（DC2）
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2012年04月-2013年03月日本学術振興会 特別研究員（PD）
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2013年04月-2017年03月国立研究開発法人理化学研究所 脳科学総合研究センター 研究員
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2017年04月-2023年03月公益財団法人東京都医学総合研究所 研究員
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2023年04月-現在東京医科歯科大学 難治疾患研究所 助教
論文・総説 【 表示 ／ 非表示 】
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Akari Nakamura, Seiichiro Sakai, Yoshitaka Taketomi, Jun Tsuyama, Yoshimi Miki, Yuichiro Hara, Nobutaka Arai, Yuki Sugiura, Hideya Kawaji, Makoto Murakami, Takashi Shichita. PLA2G2E-mediated lipid metabolism triggers brain-autonomous neural repair after ischemic stroke. Neuron. 2023.07; 111 (19): 2995-+. ( PubMed, DOI )
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Seiichiro Sakai, Takashi Shichita. Role of alarmins in poststroke inflammation and neuronal repair. Semin Immunopathol. 2023.05; 45 (3): 427-435. ( PubMed, DOI )
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Koutarou Nakamura, Seiichiro Sakai, Jun Tsuyama, Akari Nakamura, Kento Otani, Kumiko Kurabayashi, Yoshiko Yogiashi, Hisao Masai, Takashi Shichita. Extracellular DJ-1 induces sterile inflammation in the ischemic brain. PLoS Biol. 2021.05; 19 (5): e3000939. ( PubMed, DOI )
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Seiichiro Sakai, Takashi Shichita. Inflammation and neural repair after ischemic brain injury. Neurochem Int. 2019.11; 130 104316. ( PubMed, DOI )
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Taisuke Yoneda, Seiichiro Sakai, Hisato Maruoka, Toshihiko Hosoya. Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex. J Vis Exp. 2018.09; (139): ( PubMed, DOI )
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Hisato Maruoka, Nao Nakagawa, Shun Tsuruno, Seiichiro Sakai, Taisuke Yoneda, Toshihiko Hosoya. Lattice system of functionally distinct cell types in the neocortex. Science. 2017.11; 358 (6363): 610-615. ( PubMed, DOI )
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Wei Gu, Tomohiko Fukuda, Tomoya Isaji, Qinglei Hang, Ho-hsun Lee, Seiichiro Sakai, Jyoji Morise, Junya Mitoma, Hideyoshi Higashi, Naoyuki Taniguchi, Hiromu Yawo, Shogo Oka, Jianguo Gu. Loss of α1,6-Fucosyltransferase Decreases Hippocampal Long Term Potentiation: IMPLICATIONS FOR CORE FUCOSYLATION IN THE REGULATION OF AMPA RECEPTOR HETEROMERIZATION AND CELLULAR SIGNALING. J Biol Chem. 2015.07; 290 (28): 17566-17575. ( PubMed, DOI )
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Shoko Hososhima, Seiichiro Sakai, Toru Ishizuka, Hiromu Yawo. Kinetic evaluation of photosensitivity in bi-stable variants of chimeric channelrhodopsins. PLoS One. 2015; 10 (3): e0119558. ( PubMed, DOI )
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Hiromu Yawo, Toshifumi Asano, Seiichiro Sakai, Toru Ishizuka. Optogenetic manipulation of neural and non-neural functions. Dev Growth Differ. 2013.05; 55 (4): 474-490. ( PubMed, DOI )
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Hiroyuki Ohta, Seiichiro Sakai, Shin Ito, Toru Ishizuka, Yugo Fukazawa, Takehito Kemuriyama, Megumi Tandai-Hiruma, Hajime Mushiake, Yoshiaki Sato, Hiromu Yawo, Yasuhiro Nishida. Paired stimulation between CA3 and CA1 alters excitability of CA3 in the rat hippocampus. Neurosci Lett. 2013.02; 534 182-187. ( PubMed, DOI )
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Keiko Umeda, Wataru Shoji, Seiichiro Sakai, Akira Muto, Koichi Kawakami, Toru Ishizuka, Hiromu Yawo. Targeted expression of a chimeric channelrhodopsin in zebrafish under regulation of Gal4-UAS system. Neurosci Res. 2013.01; 75 (1): 69-75. ( PubMed, DOI )
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Seiichiro Sakai, Kenichi Ueno, Toru Ishizuka, Hiromu Yawo. Parallel and patterned optogenetic manipulation of neurons in the brain slice using a DMD-based projector. Neurosci Res. 2013.01; 75 (1): 59-64. ( PubMed, DOI )
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Yoshifumi Abe, Masaki Sekino, Yasushi Terazono, Hiroyuki Ohsaki, Yugo Fukazawa, Seiichiro Sakai, Hiromu Yawo, Tatsuhiro Hisatsune. Opto-fMRI analysis for exploring the neuronal connectivity of the hippocampal formation in rats. Neurosci Res. 2012.12; 74 (3-4): 248-255. ( PubMed, DOI )
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Kentaro Matsuzaki, Kenichi Miyazaki, Seiichiro Sakai, Hiromu Yawo, Norihito Nakata, Shigeki Moriguchi, Kohji Fukunaga, Akihito Yokosuka, Yutaka Sashida, Yoshihiro Mimaki, Tohru Yamakuni, Yasushi Ohizumi. Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus. Eur J Pharmacol. 2008.01; 578 (2-3): 194-200. ( PubMed, DOI )
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Jun Tsuyama, Seiichiro Sakai, Kumiko Kurabayashi, Ryuki Koyama, Yuichiro Hara, Ito Kawakami, Hideya Kawaji, Takashi Shichita. Sustaining microglial reparative function enhances stroke recovery bioRxiv. 2024.04; ( DOI )
講演・口頭発表等 【 表示 ／ 非表示 】
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酒井 誠一郎, 七田 崇. 脳梗塞後の回復期における体性感覚野へのトップダウン入力の強化. 第46回 日本神経科学大会 2023.08.02
その他業績 【 表示 ／ 非表示 】
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「 脂肪酸代謝を介した脳の修復メカニズムを発見 」 ― 脂質を投与することにより脳梗塞後の神経症状が改善 ―，2023年07月
Neuron