Takuya Kobayakawa, Kenichi Yamamoto, Aiichiro Fukutome, Marisa Arioka, Kohei Tsuji, Hirokazu Tamamura. Design and synthesis of a C2-symmetric cyclic decapeptide and its peptidomimetic as potential inhibitors against amyloid-beta aggregation. SYNLETT. 2025.04; 36 (17): 2948-2952. ( DOI )

Takuya Kobayakawa, Marisa Arioka, Kenichi Yamamoto, Kohei Tsuji, Hirokazu Tamamura. Diastereoselective synthesis of (Z)-fluoroalkene dipeptide isosteres utilizing chiral auxiliaries. Organic & Biomolecular Chemistry. 2025.04; 23 (18): 4333-4336. ( DOI )

Takuya Kobayakawa, Masaru Yokoyama, Kohei Tsuji, Sayaka Boku, Masaki Kurakami, Masayuki Fujino, Takahiro Ishii, Yutaro Miura, Soshi Nishimura, Kouki Shinohara, Kenichi Yamamoto, Peter Bolah, Osamu Kotani, Tsutomu Murakami, Hironori Sato, Hirokazu Tamamura. Development of Small-Molecule Anti-HIV-1 Agents Targeting HIV-1 Capsid Proteins. Chemical and Pharmaceutical Bulletin. 2024.01; 72 (1): 41-47. ( PubMed, DOI )

Takuya Kobayakawa, Masayuki Amano, Miyuki Nakayama, Kohei Tsuji, Takahiro Ishii, Yutaro Miura, Kouki Shinohara, Kenichi Yamamoto, Masao Matsuoka, Hirokazu Tamamura. Development of anti-HBV agents targeting HBV capsid proteins. RSC Medicinal Chemistry. 2023.10; 14 (10): 1973-1980. ( PubMed, DOI )

Kohei Tsuji, Takuya Kobayakawa, Takahiro Ishii, Nobuyo Higashi-Kuwata, Chika Azuma, Kouki Shinohara, Yutaro Miura, Kenichi Yamamoto, Soshi Nishimura, Shin-ichiro Hattori, Haydar Bulut, Hiroaki Mitsuya, Hirokazu Tamamura. Exploratory Studies of Effective Inhibitors against the SARS-CoV-2 Main Protease by Halogen Incorporation and Amide Bond Replacement. Chemical & pharmaceutical bulletin. 2023; 71 (12): 879-886. ( PubMed, DOI )

Kenichi Yamamoto, Takuya Kobayakawa, Aiiciro Fukutome, Marisa Arioka, Kohei Tsuji and Hirokazu Tamamura. Synthesis of peptidomimetics based on a chloroalkene structure and their application in drug discovery. Pacifichem 2025 2025.12.17 Honolulu, Hawaii

Kenichi Yamamoto, Takuya Kobayakawa, Aiichiro Fukutome, Marisa Arioka, Kohei Tsuji and Hirokazu Tamamura. Synthesis of Chloroalkene-Based Paptidomimetics and Their Application as Amyloid-Beta Aggregation Inhibitors. 16TH AUSTRALIAN PEPTIDE CONFERENCE 2025.10.16 Launceston, Tasmania

Kenichi Yamamoto, Takuya Kobayakawa, Aiichiro Fukutome, Marisa Arioka, Kohei Tsuji and Hirokazu Tamamura. Design and Synthesis of a C2-Symmetric Cyclic Decapeptide and Its Peptidomimetic as Potential Inhibitors against Amyloid-beta Aggregation. 15th AFMC International Medicinal Chemistry Symposium 2025.09.25 杭州

Kenichi Yamamoto, Takuya Kobayakawa, Kohei Tsuji, and Hirokazu Tamamura. Chloroalkene-type Dipeptide Isosteres Applicated for Amyloid-beta Aggregation Inhibitors . 29th American Peptide Symposium 2025.06.15 San Diego

Kenichi Yamamoto, Takuya Kobayakawa, Kohei Tsuji, Hirokazu Tamamura. CHLOROALKENE-TYPE DIPEPTIDE ISOSTERES APPLICATED FOR AMYLOID-BETA AGGREGATION INHIBITORS. 10th Indian Peptide symposium 2025.02.26 Indian Institute of Science Education and Research Pune