Personnel Information

写真a

OKIYAMA Naoko


Job title

Professor

Field Introduction URL

https://www.tmd.ac.jp/med/derm/index.html

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Graduating School 【 display / non-display 】

  • Yamanashi Medical University, Faculty of Medicine, 1999.03, Graduated

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Graduate School 【 display / non-display 】

  • Tokyo Medical and Dental University, Doctor's Course, Completed

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Campus Career 【 display / non-display 】

  • 2022.02
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Environmental Response， Dermatology， Professor
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Academic Society Affiliations 【 display / non-display 】

  • Japanese Dermatological Association

  • Japanese Society of Allergology

  • Japanese Society of Investigative Dermatology

  • Japanese Society for Immunology

  • The Japanese Society of Clinical Immunology

  • Japan College of Rheumatology

  • The Japanese Society of Cutaneous Immunology and Allergy

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Research Areas 【 display / non-display 】

  • Dermatology

  • Connective tissue disease and allergy

  • Immunology

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Qualification Acquired 【 display / non-display 】

  • Doctor

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Published Papers & Misc 【 display / non-display 】

  1. Ebisawa Yuka, Masumoto Shoichi, Okiyama Naoko, Yoshimoto Hisashi, Maeno Tetsuhiro. The Onset of Food-dependent Exercise-induced Anaphylaxis in an Elderly Patient(タイトル和訳中) Internal Medicine. 2023.10; 62 (19): 2907-2909. ( ichushi )

  2. Oyama M, Ohnuki Y, Uruha A, Saito Y, Nishimori Y, Suzuki S, Inoue M, Tanboon J, Okiyama N, Shiina T, Nishino I, Suzuki S.. Association Between HLA Alleles and Autoantibodies in Dermatomyositis Defined by Sarcoplasmic Expression of Myxovirus Resistance Protein A. Journal of Rheumatology. 2023.09; 50 (9): 1159-1164.

  3. Inaba M, Fukushima H, Hara M, Hosaka S, Fujiyama S, Maruo K, Nomura T, Okiyama N, Takada H.. Antigen-specific T cell balance reveals Why patients with atopic dermatitis fail to achieve immune tolerance. Clinical Immunology. 2023.07; 252 109649.

  4. Tanboon J, Inoue M, Hirakawa S, Tachimori H, Hayashi S, Noguchi S, Okiyama N, Fujimoto M, Suzuki S, Nishino I.. Muscle pathology of antisynthetase syndrome according to antibody subtypes. Brain Pathology. 2023.07; 33 (4): e13155.

  5. Namiki Takeshi, Makiguchi Moe, Wada Shogo, Al-Busani Hind, Nishida Makiko, Ugajin Tsukasa, Miura Keiko, Yokoyama Kota, Okiyama Naoko. The potential value of thallium-201 scintigraphy in the diagnosis of squamous cell carcinoma arising from extensive pyoderma(タイトル和訳中) The Journal of Dermatology. 2023.07; 50 (7): 942-945. ( ichushi )

  6. Mouri Mariko, Kanamori Toru, Tanaka Eriko, Hiratoko Kanako, Okubo Mariko, Inoue Michio, Morio Tomohiro, Shimizu Masaki, Nishino Ichizo, Okiyama Naoko, Mori Masaaki. Hepatic veno-occlusive disease accompanied by thrombotic microangiopathy developed during treatment of juvenile dermatomyositis and macrophage activation syndrome: A case report(タイトル和訳中) Modern Rheumatology Case Reports. 2023.07; 7 (2): 404-409. ( ichushi )

  7. Oya K, Nakamura Y, Watanabe R, Tanaka R, Ichimura Y, Kubota N, Matsumura Y, Tahara H, Okiyama N, Fujimoto M, Nomura T, Fujisawa Y.. Eribulin mesylate exerts antitumor effects via CD103. Oncoimmunology. 2023.05; 12 (1): 2218782.

  8. Iwata Masahiro, Ogawa Tatsuya, Anju Keisuke, Okiyama Naoko, Nomura Toshifumi. Adult-onset Still's disease following mRNA-1273 Moderna COVID-19 vaccination: A case report(タイトル和訳中) Journal of Cutaneous Immunology and Allergy. 2023.04; 6 (2): 66-67. ( ichushi )

  9. Konishi Risa, Ichimura Yuki, Okiyama Naoko. Murine models of idiopathic inflammatory myopathy(タイトル和訳中) Immunological Medicine. 2023.03; 46 (1): 9-14. ( ichushi )

  10. Konishi R, Ichimura Y, Okiyama N. Murine models of idiopathic inflammatory myopathy. Immunological medicine. 2023.03; 46 (1): 9-14. ( PubMed, DOI )

  11. Kubota N, Tanaka R, Ichimura Y, Konishi R, Tso JY, Tsurushita N, Nomura T, Okiyama N.. Blockade of CD122 on memory T cells in the skin suppresses sclerodermatous graft-versus-host disease. Journal of Dermatological Science. 2023.03; 109 (3): 127-135.

  12. Tanaka R, Ichimura Y, Kubota N, Konishi R, Nakamura Y, Mizuno S, Takahashi S, Fujimoto M, Nomura T, Okiyama N.. The Role of PD-L1 on Langerhans Cells in the Regulation of Psoriasis. Journal of Investigative Dermatology. 2022.12; 142 (12): 3167-3174.

  13. Ichimura Y, Ikei H, Konishi R, Zeniya M, Okai T, Nomura T, Negishi K, Okiyama N. Relevance of leukemia inhibitory factor to anti-melanoma differentiation-associated gene 5 antibody-positive interstitial lung disease. Rheumatology (Oxford, England). 2022.11; 62 (6): 2267-2271. ( PubMed, DOI )

  14. Wada S, Namiki T, Takano M, Miura K, Okiyama N. Kaposi-Sarkom mit HHV-8-Immunreaktivität in einer Magenläsion, aber nicht in Hautläsionen. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 2022.11; 20 (11): 1511-1513. ( PubMed, DOI )

  15. Mouri M, Kanamori T, Tanaka E, Hiratoko K, Okubo M, Inoue M, Morio T, Shimizu M, Nishino I, Okiyama N, Mori M. Hepatic veno-occlusive disease accompanied by thrombotic microangiopathy developing during treatment of juvenile dermatomyositis and macrophage activation syndrome: A case report. Modern rheumatology case reports. 2022.11; 20 (11): 1511-1513. ( PubMed, DOI )

  16. Wada S, Namiki T, Takano M, Miura K, Okiyama N. Kaposi sarcoma with HHV-8 immunoreactivity in a gastric lesion but not in skin lesions. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 2022.11; 20 (11): 1512-1514. ( PubMed, DOI )

  17. Hiraiwa T, Hanami Y, Okiyama N, Konishi R, Ichimura Y, Yamamoto T.. Clinically amyopathic dermatomyositis with diffuse erosive erythema in a patient with anti-small ubiquitin-like modifier activating enzyme antibody. International Journal of Dermatology. 2022.10; 61 (10): e389-e391.

  18. Ogawa T, Ishitsuka Y, Nakamura Y, Watanabe R, Okiyama N, Fujisawa Y, Fujimoto M, Roop DR, Nomura T. Loricrin Protects against Chemical Carcinogenesis. The Journal of investigative dermatology. 2022.07; 142 (7): 2023-2026.e1. ( PubMed, DOI )

  19. Tanaka R, Ichimura Y, Kubota N, Konishi R, Nakamura Y, Mizuno S, Takahashi S, Fujimoto M, Nomura T, Okiyama N. The Role of PD-L1 on Langerhans Cells in the Regulation of Psoriasis. The Journal of investigative dermatology. 2022.07; 142 (12): 3167-3174.e9. ( PubMed, DOI )

  20. Nagamori T, Ishibazawa E, Yoshida Y, Izumi K, Sato M, Ichimura Y, Okiyama N, Nishino I, Azuma H. A Continuous Increase in CXC-Motif Chemokine Ligand 10 in a Case of Anti-Nuclear Matrix Protein-2-Positive Juvenile Dermatomyositis. Journal of medical cases. 2022.06; 13 (6): 290-296. ( PubMed, DOI )

  21. Kobayashi T, Nakano T, Ogata H, Sato N, Yamaide F, Yamashita Y, Chikaraishi K, Hino M, Nishino I, Ichimura Y, Okiyama N, Hamada H. A 10-year-old girl with low-grade B cell lymphoma complicated by anti-nuclear matrix protein 2 autoantibody-positive juvenile dermatomyositis. Rheumatology (Oxford, England). 2022.05; 61 (6): e143-e145. ( PubMed, DOI )

  22. Okune M, Okiyama N, Fukuzono M, Sasaki K, Nomura T. Development of systemic lupus erythematosus after dupilumab treatment in a case of atopic dermatitis. The Journal of dermatology. 2022.05; 49 (5): 556-559. ( PubMed, DOI )

  23. Fukuzono M, Okiyama N, Iwasaki R, Endo R, Sasaki K, Inoue S, Nomura T. Intravenous immunoglobulin-induced thrombocytopenia: a case report and review of the literature European journal of dermatology : EJD. 2022.05; 32 (3): 373-376. ( PubMed, DOI )

  24. Okune Mari, Okiyama Naoko, Fukuzono Maki, Sasaki Katsuhito, Nomura Toshifumi. デュピルマブ治療後に全身性エリテマトーデスを発症したアトピー性皮膚炎の1例(Development of systemic lupus erythematosus after dupilumab treatment in a case of atopic dermatitis) The Journal of Dermatology. 2022.05; 49 (5): 556-559. ( ichushi )

  25. Ichimura Yuki, Konishi Risa, Shobo Miwako, Inoue Sae, Okune Mari, Maeda Akemi, Tanaka Ryota, Kubota Noriko, Matsumoto Isao, Ishii Akiko, Tamaoka Akira, Shimbo Asami, Mori Masaaki, Morio Tomohiro, Kishi Takayuki, Miyamae Takako, Tanboon Jantima, Inoue Michio, Nishino Ichizo, Fujimoto Manabu, Nomura Toshifumi, Okiyama Naoko. Reliability of antinuclear matrix protein 2 antibody assays in idiopathic inflammatory myopathies is dependent on target protein properties(和訳中) The Journal of Dermatology. 2022.04; 49 (4): 441-447. ( ichushi )

  26. Ichimura Y, Konishi R, Shobo M, Inoue S, Okune M, Maeda A, Tanaka R, Kubota N, Matsumoto I, Ishii A, Tamaoka A, Shimbo A, Mori M, Morio T, Kishi T, Miyamae T, Tanboon J, Inoue M, Nishino I, Fujimoto M, Nomura T, Okiyama N. Reliability of antinuclear matrix protein 2 antibody assays in idiopathic inflammatory myopathies is dependent on target protein properties. The Journal of dermatology. 2022.04; 49 (4): 441-447. ( PubMed, DOI )

  27. Okiyama Naoko, Tanaka Ryota. 免疫チェックポイント阻害剤による様々な臓器における免疫関連有害事象(Immune-related adverse events in various organs caused by immune checkpoint inhibitors) Allergology International. 2022.04; 71 (2): 169-178. ( ichushi )

  28. Okada Y, Izumi R, Hosaka T, Watanabe S, Shijo T, Hatchome N, Konishi R, Ichimura Y, Okiyama N, Suzuki N, Misu T, Aoki M. Anti-NXP2 antibody-positive dermatomyositis developed after COVID-19 manifesting as type I interferonopathy. Rheumatology (Oxford, England). 2022.04; 61 (4): e90-e92. ( PubMed, DOI )

  29. Okiyama N, Tanaka R. Immune-related adverse events in various organs caused by immune checkpoint inhibitors. Allergology international : official journal of the Japanese Society of Allergology. 2022.04; 71 (2): 169-178. ( PubMed, DOI )

  30. Ichimura Y, Konishi R, Shobo M, Inoue S, Okune M, Maeda A, Tanaka R, Kubota N, Matsumoto I, Ishii A, Tamaoka A, Shimbo A, Mori M, Morio T, Kishi T, Miyamae T, Tanboon J, Inoue M, Nishino I, Fujimoto M, Nomura T, Okiyama N. Anti-nuclear matrix protein 2 antibody-positive inflammatory myopathies represent extensive myositis without dermatomyositis-specific rash. Rheumatology (Oxford, England). 2022.03; 61 (3): 1222-1227. ( PubMed, DOI )

  31. Kakurai Masakazu, Okiyama Naoko, Ogawa Tatsuya, Fukuzono Maki, Kubota Noriko, Fujisawa Yasuhiro, Kajita Tomohide, Ishii Akiko, Tamaoka Akira, Nomura Toshifumi. Intertwined vascular skin manifestations in a patient with Sjoegren syndrome: A case report(和訳中) Journal of Cutaneous Immunology and Allergy. 2022.02; 5 (1): 22-23. ( ichushi )

  32. Hiraiwa T, Hanami Y, Okiyama N, Konishi R, Ichimura Y, Yamamoto T. Clinically amyopathic dermatomyositis with diffuse erosive erythema in a patient with anti-small ubiquitin-like modifier activating enzyme antibody. International journal of dermatology. 2022.02; 61 (10): e389-e391. ( PubMed, DOI )

  33. Tanboon J, Inoue M, Saito Y, Tachimori H, Hayashi S, Noguchi S, Okiyama N, Fujimoto M, Nishino I. Dermatomyositis: Muscle Pathology According to Antibody Subtypes. Neurology. 2022.02; 98 (7): e739-e749. ( PubMed, DOI )

  34. Miyahara Hanako, Okiyama Naoko, Okune Mari, Konishi Risa, Miyamoto Masahide, Hara Monami, Iwabuchi Atsushi, Takada Hidetoshi, Nishino Ichizo, Nomura Toshifumi. Case of anti-nuclear matrix protein 2 antibody-positive juvenile dermatomyositis preceded by linear cutaneous lupus erythematosus on the face(和訳中) The Journal of Dermatology. 2022.01; 49 (1): e18-e19. ( ichushi )

  35. Konishi Risa, Tanaka Ryota, Inoue Sae, Ichimura Yuki, Nomura Toshifumi, Okiyama Naoko. Evaluation of apremilast, an oral phosphodiesterase 4 inhibitor, for refractory cutaneous dermatomyositis: A phase 1b clinical trial(和訳中) The Journal of Dermatology. 2022.01; 49 (1): 118-123. ( ichushi )

  36. Miyahara H, Okiyama N, Okune M, Konishi R, Miyamoto M, Hara M, Iwabuchi A, Takada H, Nishino I, Nomura T. Case of anti-nuclear matrix protein 2 antibody-positive juvenile dermatomyositis preceded by linear cutaneous lupus erythematosus on the face. The Journal of dermatology. 2022.01; 49 (1): e18-e19. ( PubMed, DOI )

  37. Imanaka Y, Nakagawa Y, Yamaoka T, Kotobuki Y, Hayashi M, Katayama I, Ichimura Y, Okiyama N, Fujimoto M. Refractory dermatomyositis which developed in a patient with silicone breast implants. Allergology international : official journal of the Japanese Society of Allergology. 2022.01; 71 (1): 158-160. ( PubMed, DOI )

  38. Imanaka Yoko, Nakagawa Yukinobu, Yamaoka Toshifumi, Kotobuki Yorihisa, Hayashi Misa, Katayama Ichiro, Ichimura Yuki, Okiyama Naoko, Fujimoto Manabu. Refractory dermatomyositis which developed in a patient with silicone breast implants(和訳中) Allergology International. 2022.01; 71 (1): 158-160. ( ichushi )

  39. Ishitsuka Y, Ogawa T, Nakamura Y, Kubota N, Fujisawa Y, Watanabe R, Okiyama N, Fujimoto M, Roop DR, Ishida-Yamamoto A. Loricrin and NRF2 Coordinate Cornification. JID innovations : skin science from molecules to population health. 2022.01; 2 (1): 100065. ( PubMed, DOI )

  40. Konishi R, Tanaka R, Inoue S, Ichimura Y, Nomura T, Okiyama N. Evaluation of apremilast, an oral phosphodiesterase 4 inhibitor, for refractory cutaneous dermatomyositis: A phase 1b clinical trial. The Journal of dermatology. 2022.01; 49 (1): 118-123. ( PubMed, DOI )

  41. Tanaka R, Ichimura Y, Kubota N, Saito A, Nakamura Y, Ishitsuka Y, Watanabe R, Fujisawa Y, Mizuno S, Takahashi S, Fujimoto M, Okiyama N. Differential Involvement of Programmed Cell Death Ligands in Skin Immune Responses. The Journal of investigative dermatology. 2022.01; 142 (1): 145-154.e8. ( PubMed, DOI )

  42. Matsumura Yutaka, Watanabe Rei, Niijima Yasuko, Kawakita Haruka, Furuta Junichi, Nakamura Yoshiyuki, Ishitsuka Yosuke, Okiyama Naoko, Fujisawa Yasuhiro, Fujimoto Manabu. 薬剤性過敏症症候群におけるエフェクターB細胞の活性化の可能性(Possible activation of effector B cells during drug-induced hypersensitivity syndrome) Journal of Cutaneous Immunology and Allergy. 2021.12; 4 (6): 166-169. ( ichushi )

  43. Okiyama N, Iwasaki R, Fukuzono M, Endo R, Inoue S, Ichimura Y, Sato K, Tajiri K, Ieda M, Nomura T. Successful treatment of pulmonary hypertension with immunosuppressive therapy in a case of anti-synthetase syndrome. The Journal of dermatology. 2021.11; 48 (11): e545-e546. ( PubMed, DOI )

  44. Okiyama Naoko, Iwasaki Riko, Fukuzono Maki, Endo Rumiko, Inoue Sae, Ichimura Yuki, Sato Kimi, Tajiri Kazuko, Ieda Masaki, Nomura Toshifumi. 抗合成酵素症候群患者における免疫抑制療法による肺高血圧症の治療(Successful treatment of pulmonary hypertension with immunosuppressive therapy in a case of anti-synthetase syndrome) The Journal of Dermatology. 2021.11; 48 (11): e545-e546. ( ichushi )

  45. Fukuzono M, Sasaki K, Ichimura Y, Inoue S, Iwasaki R, Imai H, Saito A, Kubota N, Tanaka R, Nakamura Y, Fujisawa Y, Fujimoto M, Nomura T, Okiyama N. A case of anti-PL-7 antibody-positive anti-synthetase syndrome with dermatomyositis-associated erythema induced sclerodermatous changes. Rheumatology (Oxford, England). 2021.10; 60 (10): e362-e364. ( PubMed, DOI )

  46. Oya Kazumasa, Ishitsuka Yosuke, Nakamura Yoshiyuki, Watanabe Rei, Okiyama Naoko, Fujimoto Manabu, Fujisawa Yasuhiro. Erdheim-Chester病における丘疹結節性病変(Papulonodular lesions in Erdheim-Chester disease) The Journal of Dermatology. 2021.09; 48 (9): e445-e446. ( ichushi )

  47. Oya K, Ishitsuka Y, Nakamura Y, Watanabe R, Okiyama N, Fujimoto M, Fujisawa Y. Papulonodular lesions in Erdheim-Chester disease. The Journal of dermatology. 2021.09; 48 (9): e445-e446. ( PubMed, DOI )

  48. Kawakami T, Okiyama N, Kodera M, Seishima M, Yamaguchi Y. The relationship between anti-phosphatidylserine/prothrombin complex IgM antibodies and cutaneous ulcers in patients with cutaneous vasculitis. The Journal of dermatology. 2021.09; 48 (9): 1457-1458. ( PubMed, DOI )

  49. Shiga M, Miyazaki J, Tanuma K, Nagumo Y, Yoshino T, Kandori S, Negoro H, Kojima T, Tanaka R, Okiyama N, Fujisawa Y, Watanabe M, Yamasaki S, Kiyohara H, Watanabe M, Sato TA, Tahara H, Nishiyama H, Yano I. The liposome of trehalose dimycolate extracted from M. bovis BCG induces antitumor immunity via the activation of dendritic cells and CD8<sup>+</sup> T cells. Cancer immunology, immunotherapy : CII. 2021.09; 70 (9): 2529-2543. ( PubMed, DOI )

  50. Ogawa T, Ishitsuka Y, Nakamura Y, Watanabe R, Okiyama N, Fujisawa Y, Fujimoto M. PD-1 Regulates Passive Anaphylaxis: A Possible Role of the Mast Cell Intracellular Inhibitory Signal. Allergy, asthma & immunology research. 2021.09; 13 (5): 819-821. ( PubMed, DOI )

  51. Nakamura Y, Ishitsuka Y, Sasaki K, Ishizuki S, Tanaka R, Okiyama N, Furuta J, Fujimoto M, Yamada T, Fujisawa Y. A prospective, phase II study on the safety and efficacy of negative pressure closure for the stabilization of split-thickness skin graft in large or muscle-exposing defects: The NPSG study. The Journal of dermatology. 2021.09; 48 (9): 1350-1356. ( PubMed, DOI )

  52. Nakajima M, Matsuyama M, Kawaguchi M, Matsumura S, Kiwamoto T, Matsuno Y, Morishima Y, Yoshida K, Sherpa MT, Yazaki K, Tanaka R, Okiyama N, Muratani M, Ishii Y, Hizawa N. Depletion of PD-1 or PD-L1 did not affect the mortality of mice infected with Mycobacterium avium. Scientific reports. 2021.09; 11 (1): 18008. ( PubMed, DOI )

  53. Maeda A, Nakamura Y, Ishizuki S, Kubota N, Okiyama N, Endo R, Iwasaki R, Oya K, Fujisawa Y. Invasive Squamous Cell Carcinoma and Numerous Bowen Disease Lesions of the Hand and Foot With Infection of HPV-18 and HPV-45. The American Journal of dermatopathology. 2021.09; 43 (9): 676-678. ( PubMed, DOI )

  54. Okiyama N, Ichimura Y, Shobo M, Tanaka R, Kubota N, Saito A, Ishitsuka Y, Watanabe R, Fujisawa Y, Nakamura Y, Murakami A, Kayama H, Takeda K, Fujimoto M. Immune response to dermatomyositis-specific autoantigen, transcriptional intermediary factor 1γ can result in experimental myositis. Annals of the rheumatic diseases. 2021.09; 80 (9): 1201-1208. ( PubMed, DOI )

  55. Nakamura Yoshiyuki, Ishitsuka Yosuke, Sasaki Katsuhito, Ishizuki Shoichiro, Tanaka Ryota, Okiyama Naoko, Furuta Junichi, Fujimoto Manabu, Yamada Takeshi, Fujisawa Yasuhiro. 広範囲または筋肉露出を伴う皮膚欠損に対する植皮片固定のための陰圧閉鎖法の安全性と有効性に関する前向き第II相試験　NPSG試験(A prospective, phase II study on the safety and efficacy of negative pressure closure for the stabilization of split-thickness skin graft in large or muscle-exposing defects: The NPSG study) The Journal of Dermatology. 2021.09; 48 (9): 1350-1356. ( ichushi )

  56. Kawakami Tamihiro, Okiyama Naoko, Kodera Masanari, Seishima Mariko, Yamaguchi Yukie. 皮膚血管炎患者における抗ホスファチジルセリン/プロトロンビン複合体IgM抗体と皮膚潰瘍との関係性(The relationship between anti-phosphatidylserine/prothrombin complex IgM antibodies and cutaneous ulcers in patients with cutaneous vasculitis) The Journal of Dermatology. 2021.09; 48 (9): 1457-1458. ( ichushi )

  57. Oya K, Nakamura Y, Zhenjie Z, Tanaka R, Okiyama N, Ichimura Y, Ishitsuka Y, Saito A, Kubota N, Watanabe R, Tahara H, Fujimoto M, Fujisawa Y. Combination Treatment of Topical Imiquimod Plus Anti-PD-1 Antibody Exerts Significantly Potent Antitumor Effect. Cancers. 2021.08; 13 (16): ( PubMed, DOI )

  58. Koguchi-Yoshioka Hanako, Watanabe Rei, Matsumura Yutaka, Ishitsuka Yosuke, Inoue Sae, Furuta Junichi, Nakamura Yoshiyuki, Okiyama Naoko, Matsuzaka Takashi, Shimano Hitoshi, Fujisawa Yasuhiro, Fujimoto Manabu. 乾癬において治療選択の予測因子となる可能性がある血清乳酸脱水素酵素値(Serum lactate dehydrogenase level as a possible predictor of treatment preference in psoriasis) Journal of Dermatological Science. 2021.08; 103 (2): 109-115. ( ichushi )

  59. Koguchi-Yoshioka H, Watanabe R, Matsumura Y, Ishitsuka Y, Inoue S, Furuta J, Nakamura Y, Okiyama N, Matsuzaka T, Shimano H, Fujisawa Y, Fujimoto M. Serum lactate dehydrogenase level as a possible predictor of treatment preference in psoriasis. Journal of dermatological science. 2021.08; 103 (2): 109-115. ( PubMed, DOI )

  60. Saito A, Ichimura Y, Kubota N, Tanaka R, Nakamura Y, Fujisawa Y, Watanabe R, Ishitsuka Y, Fujimoto M, Okiyama N. IFN-γ-Stimulated Apoptotic Keratinocytes Promote Sclerodermatous Changes in Chronic Graft-Versus-Host Disease. The Journal of investigative dermatology. 2021.06; 141 (6): 1473-1481.e4. ( PubMed, DOI )

  61. Tawara N, Yamashita S, Nagatoshi C, Nakajima M, Ichimura Y, Okiyama N, Ando Y. Anti-NXP2 antibody-positive dermatomyositis with aortic thrombus in normal aortic wall. Rheumatology (Oxford, England). 2021.05; 60 (5): e159-e161. ( PubMed, DOI )

  62. Komura K, Ichimura Y, Okiyama N, Watanabe K, Muramoto H, Matsushita T. Augmented interferon I signaling in a patient with COVID toes. The Journal of dermatology. 2021.05; 48 (5): e242-e243. ( PubMed, DOI )

  63. Kubota N, Saito A, Tanaka R, Nakamura Y, Watanabe R, Fujisawa Y, Ishitsuka Y, Clausen BE, Fujimoto M, Okiyama N. Langerhans Cells Suppress CD8<sup>+</sup> T Cells In Situ during Mucocutaneous Acute Graft-Versus-Host Disease. The Journal of investigative dermatology. 2021.05; 141 (5): 1177-1187.e3. ( PubMed, DOI )

  64. Komura Kazuhiro, Ichimura Yuki, Okiyama Naoko, Watanabe Kazuyoshi, Muramoto Hiroaki, Matsushita Takashi. COVID toes患者におけるインターフェロンIシグナルの増強(Augmented interferon I signaling in a patient with COVID toes) The Journal of Dermatology. 2021.05; 48 (5): e242-e243. ( ichushi )

  65. Okiyama N. Clinical Features and Cutaneous Manifestations of Juvenile and Adult Patients of Dermatomyositis Associated with Myositis-Specific Autoantibodies. Journal of clinical medicine. 2021.04; 10 (8): ( PubMed, DOI )

  66. Nakamura Yoshiyuki, Sasaki Katsuhito, Ishizuki Shoichiro, Inoue Sae, Okune Mari, Kubota Noriko, Okiyama Naoko, Furuta Junichi, Fujisawa Yasuhiro. 外来での皮膚腫瘍手術後の扁平上皮癌の浸潤病変とin situ病変は術後手術部位感染症の独立予測因子である　患者512名を対象とした後方視的研究(Invasive and in situ lesions of squamous cell carcinoma are independent factors for postoperative surgical-site infection after outpatient skin tumors surgery: A retrospective study of 512 patients) The Journal of Dermatology. 2021.04; 48 (4): 497-501. ( ichushi )

  67. Shimizu Tatsuya, Saito Chie, Watanabe Megumi, Ishii Ryota, Kawamura Tetsuya, Nagai Kei, Fujita Akiko, Kaneko Shuzo, Kai Hirayasu, Morito Naoki, Usui Joichi, Yokosawa Masahiro, Kondo Yuya, Inoue Sae, Okiyama Naoko, Yamagata Kunihiro. 多臓器浸潤を合併した抗PM/Scl抗体陽性全身性強皮症(Anti-PM/Scl Antibody-positive Systemic Sclerosis Complicated by Multiple Organ Involvement) Internal Medicine. 2021.04; 60 (7): 1101-1107. ( ichushi )

  68. Shimizu T, Saito C, Watanabe M, Ishii R, Kawamura T, Nagai K, Fujita A, Kaneko S, Kai H, Morito N, Usui J, Yokosawa M, Kondo Y, Inoue S, Okiyama N, Yamagata K. Anti-PM/Scl Antibody-positive Systemic Sclerosis Complicated by Multiple Organ Involvement. Internal medicine (Tokyo, Japan). 2021.04; 60 (7): 1101-1107. ( PubMed, DOI )

  69. Nakamura Y, Sasaki K, Ishizuki S, Inoue S, Okune M, Kubota N, Okiyama N, Furuta J, Fujisawa Y. Invasive and in situ lesions of squamous cell carcinoma are independent factors for postoperative surgical-site infection after outpatient skin tumors surgery: A retrospective study of 512 patients. The Journal of dermatology. 2021.04; 48 (4): 497-501. ( PubMed, DOI )

  70. Kume M, Arase N, Okiyama N, Koguchi-Yoshioka H, Tada T, Saruban H, Fujimoto M. Unilateral heliotrope rash: a warning sign for anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis. Rheumatology (Oxford, England). 2021.04; 60 (4): e134-e135. ( PubMed, DOI )

  71. Konishi Risa, Ishitsuka Yosuke, Imai Hidemi, Inoue Sae, Nakamura Yoshiyuki, Okiyama Naoko, Oshika Tetsuro, Hiraoka Takahiro, Fujisawa Yasuhiro. 二重免疫チェックポイント遮断による腫瘍崩壊症候群と副次的な免疫活性化(Tumor lysis syndrome and collateral immune activation in dual checkpoint blockade) Journal of Cutaneous Immunology and Allergy. 2021.04; 4 (2): 39-40. ( ichushi )

  72. Kishi T, Tani Y, Okiyama N, Mizuochi K, Ichimura Y, Harigai M, Nagata S, Miyamae T. Anti-SAE autoantibody-positive Japanese patient with juvenile dermatomyositis complicated with interstitial lung disease - a case report. Pediatric rheumatology online journal. 2021.03; 19 (1): 34. ( PubMed, DOI )

  73. Inoue S, Watanabe R, Ishitsuka Y, Nakamura Y, Fujisawa Y, Okiyama N, Fujimoto M. Successful Treatment of Acrodermatitis Continua of Hallopeau with an Anti-IL-17A Agent. Indian journal of dermatology. 2021.03; 66 (2): 225. ( PubMed, DOI )

  74. Kurano M, Nakamura Y, Kubota N, Okiyama N, Ishitsuka Y, Tanaka R, Furuta J, Watanabe R, Fujisawa Y. Mucinous metaplasia with glandular structures of the labia minora. The Journal of dermatology. 2021.02; 48 (2): e118-e119. ( PubMed, DOI )

  75. Ishizuki Shoichiro, Nakamura Yoshiyuki, Maruyama Hiroshi, Okiyama Naoko, Tanaka Ryota, Oya Kazumasa, Furuta Junichi, Fujisawa Yasuhiro. ダーモスコピーで広範囲に平行に走る色素沈着を呈した近位爪郭の色素性Bowen病(Pigmented Bowen's disease on the proximal nail fold with extensive, parallel pigmented lines in dermoscopy) The Journal of Dermatology. 2021.02; 48 (2): e88-e89. ( ichushi )

  76. Kessoku R, Nakamura Y, Ishitsuka Y, Tanaka R, Endo R, Watanabe R, Furuta J, Okiyama N, Fujisawa Y. Recurrent multiple cutaneous aseptic abscesses with spontaneous regression: An unusual case report. The Journal of dermatology. 2021.02; 48 (2): e116-e117. ( PubMed, DOI )

  77. Kurano Mika, Nakamura Yoshiyuki, Kubota Noriko, Okiyama Naoko, Ishitsuka Yosuke, Tanaka Ryota, Furuta Junichi, Watanabe Rei, Fujisawa Yasuhiro. 小陰唇の腺性構造を伴う粘液性化生(Mucinous metaplasia with glandular structures of the labia minora) The Journal of Dermatology. 2021.02; 48 (2): e118-e119. ( ichushi )

  78. Kessoku Reiko, Nakamura Yoshiyuki, Ishitsuka Yosuke, Tanaka Ryota, Endo Ruriko, Watanabe Rei, Furuta Junichi, Okiyama Naoko, Fujisawa Yasuhiro. 自然消退した再発性多発性皮膚無菌性膿瘍　稀な1症例の報告(Recurrent multiple cutaneous aseptic abscesses with spontaneous regression: An unusual case report) The Journal of Dermatology. 2021.02; 48 (2): e116-e117. ( ichushi )

  79. Ishizuki S, Nakamura Y, Maruyama H, Okiyama N, Tanaka R, Oya K, Furuta J, Fujisawa Y. Pigmented Bowen's disease on the proximal nail fold with extensive, parallel pigmented lines in dermoscopy. The Journal of dermatology. 2021.02; 48 (2): e88-e89. ( PubMed, DOI )

  80. Koguchi-Yoshioka H, Watanabe R, Matsumura Y, Okiyama N, Ishitsuka Y, Nakamura Y, Fujisawa Y, Fujimoto M. The Possible Linkage of Granzyme B-Producing Skin T Cells with the Disease Prognosis of Alopecia Areata. The Journal of investigative dermatology. 2021.02; 141 (2): 427-429.e10. ( PubMed, DOI )

  81. Koguchi-Yoshioka H, Hoffer E, Cheuk S, Matsumura Y, Vo S, Kjellman P, Grema L, Ishitsuka Y, Nakamura Y, Okiyama N, Fujisawa Y, Fujimoto M, Eidsmo L, Clark RA, Watanabe R. Skin T cells maintain their diversity and functionality in the elderly. Communications biology. 2021.01; 4 (1): 13. ( PubMed, DOI )

  82. Matsumura Yutaka, Watanabe Rei, Vo Sa, Koguchi-Yoshioka Hanako, Furuta Junichi, Inoue Sae, Ishitsuka Yosuke, Nakamura Yoshiyuki, Okiyama Naoko, Fujisawa Yasuhiro, Fujimoto Manabu. インターロイキン-23は乾癬非病変皮膚においてCD103陰性Th17を亢進する(Interleukin-23 promotes CD103-negative Th17 in psoriatic non-lesional skin) Journal of Dermatological Science. 2021.01; 101 (1): 72-74. ( ichushi )

  83. Matsumura Y, Watanabe R, Vo S, Koguchi-Yoshioka H, Furuta J, Inoue S, Ishitsuka Y, Nakamura Y, Okiyama N, Fujisawa Y, Fujimoto M. Interleukin-23 promotes CD103-negative Th17 in psoriatic non-lesional skin. Journal of dermatological science. 2021.01; 101 (1): 72-74. ( PubMed, DOI )

  84. Tanboon J, Inoue M, Hirakawa S, Tachimori H, Hayashi S, Noguchi S, Suzuki S, Okiyama N, Fujimoto M, Nishino I. Pathologic Features of Anti-Mi-2 Dermatomyositis. Neurology. 2021.01; 96 (3): e448-e459. ( PubMed, DOI )

  85. Nakamura Y, Nakayama M, Nishimura B, Okiyama N, Tanaka R, Ishitsuka Y, Matsumoto S, Fujisawa Y. Case Report: Complete Response of Recurrent and Metastatic Cystadenocarcinoma of the Parotid Gland With a Single Course of Combined Nivolumab and Ipilimumab Therapy. Frontiers in oncology. 2021; 11 618201. ( PubMed, DOI )

  86. Abe S, Tsuboi H, Toko H, Honda F, Yagishita M, Hagiwara S, Kondo Y, Konishi R, Okune M, Ichimura Y, Okiyama N, Matsumoto I. Clinically amyopathic dermatomyositis associated with anti-nuclear matrix protein 2 antibody. Rheumatology advances in practice. 2021; 5 (3): rkab104. ( PubMed, DOI )

  87. Yamamoto T, Ito T, Asano Y, Sato S, Motegi SI, Ishikawa O, Matsushita T, Takehara K, Makino T, Okiyama N, Fujimoto M, Jinnin M, Ihn H. Characteristics of Japanese patients with eosinophilic fasciitis: A brief multicenter study. The Journal of dermatology. 2020.12; 47 (12): 1391-1394. ( PubMed, DOI )

  88. Yamamoto Toshiyuki, Ito Takashi, Asano Yoshihide, Sato Shinichi, Motegi Sei-ichiro, Ishikawa Osamu, Matsushita Takashi, Takehara Kazuhiko, Makino Takamitsu, Okiyama Naoko, Fujimoto Manabu, Jinnin Masatoshi, Ihn Hironobu. 好酸球性筋膜炎の日本人患者の特徴　短期の多施設共同研究(Characteristics of Japanese patients with eosinophilic fasciitis: A brief multicenter study) The Journal of Dermatology. 2020.12; 47 (12): 1391-1394. ( ichushi )

  89. Yamashita K, Kawasaki A, Matsushita T, Furukawa H, Kondo Y, Okiyama N, Nagaoka S, Shimada K, Sugii S, Katayama M, Hirohata S, Okamoto A, Chiba N, Suematsu E, Setoguchi K, Migita K, Sumida T, Tohma S, Hamaguchi Y, Hasegawa M, Sato S, Kawaguchi Y, Takehara K, Tsuchiya N. Association of functional (GA)n microsatellite polymorphism in the FLI1 gene with susceptibility to human systemic sclerosis. Rheumatology (Oxford, England). 2020.11; 59 (11): 3553-3562. ( PubMed, DOI )

  90. Miyake Z, Ishii A, Okiyama N, Tamaoka A. Amyopathic dermatomyositis combined with peripheral neuropathy. BMJ case reports. 2020.11; 13 (11): ( PubMed, DOI )

  91. Nakamura Yoshiyuki, Ishitsuka Yosuke, Tanaka Ryota, Okiyama Naoko, Watanabe Rei, Saito Akimasa, Furuta Junichi, Fujisawa Yasuhiro. BRAF/MEK阻害剤による治療時に高頻度でみられる脳転移　単一施設後ろ向き研究(Frequent brain metastases during treatment with BRAF/MEK inhibitors: A retrospective single institutional study) The Journal of Dermatology. 2020.10; 47 (10): 1191-1194. ( ichushi )

  92. Nakamura Y, Ishitsuka Y, Tanaka R, Okiyama N, Watanabe R, Saito A, Furuta J, Fujisawa Y. Frequent brain metastases during treatment with BRAF/MEK inhibitors: A retrospective single institutional study. The Journal of dermatology. 2020.10; 47 (10): 1191-1194. ( PubMed, DOI )

  93. Tanaka R, Ichimura Y, Kubota N, Saito A, Nakamura Y, Ishitsuka Y, Watanabe R, Fujisawa Y, Kanzaki M, Mizuno S, Takahashi S, Fujimoto M, Okiyama N. Activation of CD8 T cells accelerates anti-PD-1 antibody-induced psoriasis-like dermatitis through IL-6. Communications biology. 2020.10; 3 (1): 571. ( PubMed, DOI )

  94. Kubota Noriko, Inoue Sae, Saito Akimasa, Tanaka Ryota, Nakamura Yoshiyuki, Ishitsuka Yosuke, Furuta Jun-ichi, Fujisawa Yasuhiro, Okiyama Naoko. IgA血管炎の成人における消化管病変と関連する広範な紫斑病変(Widespread involvement of purpura related to gastrointestinal involvements in adults with immunoglobulin A vasculitis) Journal of Cutaneous Immunology and Allergy. 2020.10; 3 (5): 104-108. ( ichushi )

  95. Nakagawa Yukinobu, Odomari Kaori, Imanaka Yoko, Katayama Ichiro, Ichimura Yuki, Okiyama Naoko, Fujimoto Manabu. 全身皮下浮腫を呈した抗NXP-2抗体陽性皮膚筋炎の一症例(A case of anti-NXP-2-positive dermatomyositis with generalized subcutaneous edema) Journal of Cutaneous Immunology and Allergy. 2020.10; 3 (5): 115-116. ( ichushi )

  96. Okiyama N, Nakamura Y, Ishitsuka Y, Inoue S, Kubota N, Saito A, Watanabe R, Fujisawa Y, Igawa K. Successful topical treatment with ketoconazole for facial rashes refractory to dupilumab in patients with atopic dermatitis: case reports. Journal of the European Academy of Dermatology and Venereology : JEADV. 2020.09; 34 (9): e474-e476. ( PubMed, DOI )

  97. Endo R, Nakamura Y, Ishizuki S, Ishitsuka Y, Watanabe R, Okiyama N, Ito Y, Nagafuchi M, Mizokami Y, Fujisawa Y. Ulcerative esophagitis associated with combined nivolumab and ipilimumab therapy. The Journal of dermatology. 2020.08; 47 (8): e299-e300. ( PubMed, DOI )

  98. Nakamura Yoshiyuki, Inoue Sae, Maruyama Hiroshi, Matsumura Yutaka, Tanaka Ryota, Ishitsuka Yosuke, Watanabe Rei, Okiyama Naoko, Fujisawa Yasuhiro. 植皮皮膚片の偽上皮腫性増殖を伴う足首の疣状黒色腫(Verrucous melanoma of the ankle with pseudoepitheliomatous hyperplasia on the skin graft) The Journal of Dermatology. 2020.08; 47 (8): e300-e302. ( ichushi )

  99. Ogawa T, Ishitsuka Y, Nakamura Y, Kubota N, Saito A, Fujisawa Y, Watanabe R, Okiyama N, Suga Y, Roop DR, Fujimoto M. NRF2 Augments Epidermal Antioxidant Defenses and Promotes Atopy. Journal of immunology (Baltimore, Md. : 1950). 2020.08; 205 (4): 907-914. ( PubMed, DOI )

  100. Nakamura Y, Inoue S, Maruyama H, Matsumura Y, Tanaka R, Ishitsuka Y, Watanabe R, Okiyama N, Fujisawa Y. Verrucous melanoma of the ankle with pseudoepitheliomatous hyperplasia on the skin graft. The Journal of dermatology. 2020.08; 47 (8): e300-e302. ( PubMed, DOI )

  101. Endo Ruriko, Nakamura Yoshiyuki, Ishizuki Shoichiro, Ishitsuka Yosuke, Watanabe Rei, Okiyama Naoko, Ito Yoshimi, Nagafuchi Miho, Mizokami Yuji, Fujisawa Yasuhiro. ニボルマブ+イピリムマブ併用療法と関連した潰瘍性食道炎(Ulcerative esophagitis associated with combined nivolumab and ipilimumab therapy) The Journal of Dermatology. 2020.08; 47 (8): e299-e300. ( ichushi )

  102. Inoue M, Tanboon J, Hirakawa S, Komaki H, Fukushima T, Awano H, Tajima T, Yamazaki K, Hayashi R, Mori T, Shibuya K, Yamanoi T, Yoshimura H, Ogawa T, Katayama A, Sugai F, Nakayama Y, Yamaguchi S, Hayashi S, Noguchi S, Tachimori H, Okiyama N, Fujimoto M, Nishino I. Association of Dermatomyositis Sine Dermatitis With Anti-Nuclear Matrix Protein 2 Autoantibodies. JAMA neurology. 2020.07; 77 (7): 872-877. ( PubMed, DOI )

  103. Yu Yue, Furuta Junichi, Watanabe Rei, Inoue Sae, Nakamura Yoshiyuki, Ishitsuka Yosuke, Okiyama Naoko, Ishii Yoshiyuki, Fujisawa Yasuhiro. 1コースの高用量免疫グロブリン単剤静注療法で長期寛解に達した水疱性類天疱瘡症例(Case of bullous pemphigoid who achieved a long-term remission by a single course of high-dose i.v. immunoglobulin monotherapy) The Journal of Dermatology. 2020.06; 47 (6): e225-e227. ( ichushi )

  104. Yu Y, Furuta J, Watanabe R, Inoue S, Nakamura Y, Ishitsuka Y, Okiyama N, Ishii Y, Fujisawa Y. Case of bullous pemphigoid who achieved a long-term remission by a single course of high-dose i.v. immunoglobulin monotherapy. The Journal of dermatology. 2020.06; 47 (6): e225-e227. ( PubMed, DOI )

  105. Konishi R, Ishitsuka Y, Inoue S, Saito A, Nakamura Y, Watanabe R, Okiyama N, Chiba S, Nishikii H, Fujimoto M, Fujisawa Y. Aggressive conjunctival carcinoma arising on poorly controlled sun-damaged graft-versus-host disease. European journal of dermatology : EJD. 2020.06; 30 (3): 313-314. ( PubMed, DOI )

  106. Nakamura Y, Inoue S, Okiyama N, Fujisawa Y. Inverted nipple-like nevus lipomatosus cutaneous superficialis. Japanese journal of clinical oncology. 2020.06; 50 (6): 722-723. ( PubMed, DOI )

  107. Oya K, Inoue S, Saito A, Nakamura Y, Ishitsuka Y, Fujisawa Y, Watanabe R, Taguchi S, Fujimoto M, Okiyama N. Pregnancy triggers the onset of anti-transcriptional intermediary factor 1γ antibody-positive dermatomyositis: a case series. Rheumatology (Oxford, England). 2020.06; 59 (6): 1450-1451. ( PubMed, DOI )

  108. Nakamura Yoshiyuki, Inoue Sae, Okiyama Naoko, Fujisawa Yasuhiro. 陥没乳頭様の表在性脂肪腫性母斑(Inverted nipple-like nevus lipomatosus cutaneous superficialis) Japanese Journal of Clinical Oncology. 2020.06; 50 (6): 722-723. ( ichushi )

  109. Anju K, Nakamura Y, Okiyama N, Ishitsuka Y, Saito A, Watanabe R, Fujisawa Y. Angiomatoid Spitz nevus with surrounding pagetoid melanocytic proliferation on the sole of the foot: An unusual case report with immunohistochemical studies for angiogenic factors. The Journal of dermatology. 2020.05; 47 (5): 538-541. ( PubMed, DOI )

  110. Ikeda T, Kawakami T, Arimura Y, Ishiguro N, Ishizu A, Ito F, Ito-Ihara T, Okiyama N, Ono S, Suzuki K, Sugawara K, Seishima M, Kodera M, Tanaka M, Hasegawa M, Furukawa F, Yamaguchi Y, Yoshizaki A, Revised Committee for guidelines for the management of vasculitis, vascular disorders of the Japanese Dermatological Association.. Survey of Japanese dermatological vasculitis specialists on cases of cutaneous arteritis (cutaneous polyarteritis nodosa). The Journal of dermatology. 2020.05; 47 (5): 534-537. ( PubMed, DOI )

  111. Ishizuki Shoichiro, Nakamura Yoshiyuki, Okiyama Naoko, Watanabe Rei, Ishitsuka Yosuke, Fujisawa Yasuhiro. 巨大皮角を呈した鼻部扁平上皮癌　独特な臨床所見(Squamous cell carcinoma of the nose presenting with a giant cutaneous horn: A unique clinical presentation) The Journal of Dermatology. 2020.05; 47 (5): e185-e186. ( ichushi )

  112. Anju Keisuke, Nakamura Yoshiyuki, Okiyama Naoko, Ishitsuka Yosuke, Saito Akimasa, Watanabe Rei, Fujisawa Yasuhiro. 足底部周囲のPaget様メラノサイト増殖を伴う血管腫様Spitz母斑　血管新生因子の免疫組織化学所見からみた稀な症例報告(Angiomatoid Spitz nevus with surrounding pagetoid melanocytic proliferation on the sole of the foot: An unusual case report with immunohistochemical studies for angiogenic factors) The Journal of Dermatology. 2020.05; 47 (5): 538-541. ( ichushi )

  113. Nakamura Yoshiyuki, Ishizuki Shoichiro, Iwasaki Riko, Ishitsuka Yosuke, Watanabe Rei, Saito Akimasa, Furuta Junichi, Okiyama Naoko, Fujisawa Yasuhiro. 総腋窩センチネルリンパ節に検出された前腕と胸部の重複原発性悪性メラノーマ(Double primary malignant melanoma on the forearm and the chest with detection of common axillary sentinel lymph nodes) The Journal of Dermatology. 2020.05; 47 (5): e187-e188. ( ichushi )

  114. Ikeda Takaharu, Kawakami Tamihiro, Arimura Yoshihiro, Ishiguro Naoko, Ishizu Akihiro, Ito Fuyu, Ito-Ihara Toshiko, Okiyama Naoko, Ono Sachiko, Suzuki Kazuo, Sugawara Koji, Seishima Mariko, Kodera Masanari, Tanaka Maiko, Hasegawa Minoru, Furukawa Fukumi, Yamaguchi Yukie, Yoshizaki Ayumi, Revised Committee for guidelines for the management of vasculitis,vascular disorders of the Japanese Dermatological Association. 日本の皮膚血管炎専門医による皮膚動脈炎(皮膚型結節性多発動脈炎)症例のサーベイ研究(Survey of Japanese dermatological vasculitis specialists on cases of cutaneous arteritis(cutaneous polyarteritis nodosa)) The Journal of Dermatology. 2020.05; 47 (5): 534-537. ( ichushi )

  115. Nakamura Y, Ishizuki S, Iwasaki R, Ishitsuka Y, Watanabe R, Saito A, Furuta J, Okiyama N, Fujisawa Y. Double primary malignant melanoma on the forearm and the chest with detection of common axillary sentinel lymph nodes. The Journal of dermatology. 2020.05; 47 (5): e187-e188. ( PubMed, DOI )

  116. Ishizuki S, Nakamura Y, Okiyama N, Watanabe R, Ishitsuka Y, Fujisawa Y. Squamous cell carcinoma of the nose presenting with a giant cutaneous horn: A unique clinical presentation. The Journal of dermatology. 2020.05; 47 (5): e185-e186. ( PubMed, DOI )

  117. Saito Akimasa, Okiyama Naoko, Inoue Sae, Kubota Noriko, Nakamura Yoshiyuki, Ishitsuka Yosuke, Watanabe Rei, Nakano Hajime, Fujisawa Yasuhiro. 赤芽球型プロトポルフィリン症の日本人家族におけるフェロケラターゼ遺伝子の新規変異(Novel mutation of the ferrochelatase gene in a Japanese family with erythropoietic protoporphyria) The Journal of Dermatology. 2020.04; 47 (4): e114-e116. ( ichushi )

  118. Saito A, Okiyama N, Inoue S, Kubota N, Nakamura Y, Ishitsuka Y, Watanabe R, Nakano H, Fujisawa Y. Novel mutation of the ferrochelatase gene in a Japanese family with erythropoietic protoporphyria. The Journal of dermatology. 2020.04; 47 (4): e114-e116. ( PubMed, DOI )

  119. Nakamura Y, Ishizuki S, Ishitsuka Y, Watanabe R, Saito A, Furuta J, Okiyama N, Fujisawa Y. Multiple, lipid-containing, subcutaneous cysts suspected of end-stage nodular cystic fat necrosis. The Journal of dermatology. 2020.03; 47 (3): e85-e87. ( PubMed, DOI )

  120. Ogawa T, Ishitsuka Y, Inoue S, Nakamura Y, Saito A, Okiyama N, Fujisawa Y, Furuta J, Watanabe R, Fujimoto M. Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Regulates Epidermal Keratinization under Psoriatic Skin Inflammation. The American journal of pathology. 2020.03; 190 (3): 577-585. ( PubMed, DOI )

  121. Nakamura Yoshiyuki, Ishizuki Shoichiro, Ishitsuka Yosuke, Watanabe Rei, Saito Akimasa, Furuta Junichi, Okiyama Naoko, Fujisawa Yasuhiro. 末期結節性脂肪織壊死が疑われた多発性脂質含有皮下嚢胞(Multiple, lipid-containing, subcutaneous cysts suspected of end-stage nodular cystic fat necrosis) The Journal of Dermatology. 2020.03; 47 (3): e85-e87. ( ichushi )

  122. Nakamura Y, Ishizuki S, Iwasaki R, Okiyama N, Ishitsuka Y, Matsumura Y, Tanaka R, Maruyama H, Watanabe R, Fujisawa Y. Remarkable elevation of fibrinolysis markers and procalcitonin associated with dabrafenib plus trametinib combination therapy: Uncommon adverse events. The Journal of dermatology. 2020.02; 47 (2): e43-e44. ( PubMed, DOI )

  123. Nakamura Yoshiyuki, Ishizuki Shoichiro, Iwasaki Riko, Okiyama Naoko, Ishitsuka Yosuke, Matsumura Yutaka, Tanaka Ryota, Maruyama Hiroshi, Watanabe Rei, Fujisawa Yasuhiro. ダブラフェニブとトラメチニブの併用療法に関連した線溶マーカーおよびプロカルシトニンの顕著な上昇　稀な有害事象(Remarkable elevation of fibrinolysis markers and procalcitonin associated with dabrafenib plus trametinib combination therapy: Uncommon adverse events) The Journal of Dermatology. 2020.02; 47 (2): e43-e44. ( ichushi )

  124. Nakamura Y, Zhenjie Z, Oya K, Tanaka R, Ishitsuka Y, Okiyama N, Watanabe R, Fujisawa Y. Poor Lymphocyte Infiltration to Primary Tumors in Acral Lentiginous Melanoma and Mucosal Melanoma Compared to Cutaneous Melanoma. Frontiers in oncology. 2020; 10 524700. ( PubMed, DOI )

  125. Ogawa T, Ishitsuka Y, Nakamura Y, Okiyama N, Watanabe R, Fujisawa Y, Fujimoto M. Honey and Chamomile Activate Keratinocyte Antioxidative Responses via the KEAP1/NRF2 System. Clinical, cosmetic and investigational dermatology. 2020; 13 657-660. ( PubMed, DOI )

  126. Prista Widya Monica , Ishitsuka Yosuke, Kawakita Haruka, Inoue Sae, Nakamura Yoshiyuki, Watanabe Rei, Okiyama Naoko, Fujimoto Manabu, Fujisawa Yasuhiro. 爪周囲炎に類似した爪部扁平上皮癌(Nail apparatus squamous cell carcinoma mimicking paronychia) The Journal of Dermatology. 2019.12; 46 (12): e460-e461. ( ichushi )

  127. Widya Monica P, Ishitsuka Y, Kawakita H, Inoue S, Nakamura Y, Watanabe R, Okiyama N, Fujimoto M, Fujisawa Y. Nail apparatus squamous cell carcinoma mimicking paronychia. The Journal of dermatology. 2019.12; 46 (12): e460-e461. ( PubMed, DOI )

  128. Oya K, Nakamura Y, Ishitsuka Y, Okiyama N, Watanabe R, Fujisawa Y. Two cases of multiple pilosebaceous cysts with hybrid cysts. European journal of dermatology : EJD. 2019.12; 29 (6): 653-654. ( PubMed, DOI )

  129. Ogawa T, Ishitsuka Y, Saito A, Nakamura Y, Watanabe R, Okiyama N, Fujisawa Y, Fujimoto M. Immune microenvironment controls the outcome of PD-1 blockade in cutaneous immune response. Allergy. 2019.11; 74 (11): 2257-2261. ( PubMed, DOI )

  130. Saito A, Nakamura Y, Tanaka R, Inoue S, Okiyama N, Ishitsuka Y, Maruyama H, Watanabe R, Yoshida K, Ishiko A, Fujimoto M, Shinkuma S, Fujisawa Y. Unusual Bone Lesions with Osteonecrosis Mimicking Bone Metastasis of Squamous Cell Carcinoma in Recessive Dystrophic Epidermolysis Bullosa. Acta dermato-venereologica. 2019.11; 99 (12): 1166-1169. ( PubMed, DOI )

  131. Nakamura Y, Ishitsuka Y, Tanaka R, Okiyama N, Saito A, Watanabe R, Fujisawa Y. Acral lentiginous melanoma and mucosal melanoma expressed less programmed-death 1 ligand than cutaneous melanoma: a retrospective study of 73 Japanese melanoma patients. Journal of the European Academy of Dermatology and Venereology : JEADV. 2019.11; 33 (11): e424-e426. ( PubMed, DOI )

  132. Ishitsuka Y, Inoue S, Furuta J, Koguchi-Yoshioka H, Nakamura Y, Watanabe R, Okiyama N, Fujisawa Y, Enokizono T, Fukushima H, Suzuki H, Nishino I, Kosaki K, Fujimoto M. Sweat retention anhidrosis associated with tubular aggregate myopathy. The British journal of dermatology. 2019.11; 181 (5): 1104-1106. ( PubMed, DOI )

  133. Nakamura Y, Okiyama N, Ishitsuka Y, Watanabe R, Saito A, Fujimoto M, Okamura K, Suzuki T, Fujisawa Y. A toddler case of keratosis follicularis squamosa (Dohi) successfully treated with salicylic acid ointment. European journal of dermatology : EJD. 2019.10; 29 (5): 544-546. ( PubMed, DOI )

  134. Nakamura N, Izumi R, Hoshi Y, Takai Y, Ono R, Suzuki N, Nagai T, Ishii Y, Ishii T, Harigae H, Okada S, Aiba S, Okiyama N, Fujimoto M, Kuroda H, Tateyama M, Aoki M. FDG-PET detects extensive calcinosis cutis in anti-NXP2 antibody-positive dermatomyositis. Rheumatology (Oxford, England). 2019.10; 58 (10): 1888. ( PubMed, DOI )

  135. Okiyama N, Yamaguchi Y, Kodera M, Hamaguchi Y, Yokozeki H, Ishiguro N, Fujimoto M. Distinct Histopathologic Patterns of Finger Eruptions in Dermatomyositis Based on Myositis-Specific Autoantibody Profiles. JAMA dermatology. 2019.09; 155 (9): 1080-1082. ( PubMed, DOI )

  136. Vo S, Watanabe R, Koguchi-Yoshioka H, Matsumura Y, Ishitsuka Y, Nakamura Y, Okiyama N, Fujisawa Y, Fujimoto M. CD8 resident memory T cells with interleukin 17A-producing potential are accumulated in disease-naïve nonlesional sites of psoriasis possibly in correlation with disease duration. The British journal of dermatology. 2019.08; 181 (2): 410-412. ( PubMed, DOI )

  137. Inoue M, Tanboon J, Okubo M, Theerawat K, Saito Y, Ogasawara M, Indrawati LA, Uruha A, Okiyama N, Fujimoto M, Suzuki S, Nishino I. Absence of sarcoplasmic myxovirus resistance protein A (MxA) expression in antisynthetase syndrome in a cohort of 194 cases. Neuropathology and applied neurobiology. 2019.08; 45 (5): 523-524. ( PubMed, DOI )

  138. Kubota N, Furuta JI, Onizawa S, Saito A, Nakamura Y, Ishitsuka Y, Watanabe R, Fujisawa Y, Okiyama N, Fujimoto M. Oral pilocarpine alleviates the symptoms of acquired idiopathic generalised anhidrosis. European journal of dermatology : EJD. 2019.08; 29 (4): 422-423. ( PubMed, DOI )

  139. Takamuki R, Okiyama N, Inoue S, Endo R, Kondo Y, Chino Y, Sumida T, Fujimoto M. Successful treatment of refractory cutaneous lupus vasculitis with i.v. immunoglobulin. The Journal of dermatology. 2019.07; 46 (7): e253-e255. ( PubMed, DOI )

  140. Takamuki Risa, Okiyama Naoko, Inoue Sae, Endo Ruriko, Kondo Yuya, Chino Yusuke, Sumida Takayuki, Fujimoto Manabu. 静脈内免疫グロブリンによる治療が奏効した難治性皮膚ループス血管炎(Successful treatment of refractory cutaneous lupus vasculitis with i.v. immunoglobulin) The Journal of Dermatology. 2019.07; 46 (7): e253-e255. ( ichushi )

  141. Nakamura Yoshiyuki, Sasaki Katsuhito, Fujisawa Yasuhiro, Okiyama Naoko, Ishitsuka Yosuke, Oya Kazumasa, Watanabe Rei, Fujimoto Manabu. 広範な石灰化を伴う鉛筆芯肉芽腫　稀な1症例報告(Pencil-core granuloma with extensive calcinosis: An unusual case report) The Journal of Dermatology. 2019.06; 46 (6): e193-e195. ( ichushi )

  142. Ishizuki S, Nakamura Y, Okiyama N, Saito A, Ishitsuka Y, Watanabe R, Fujimoto M, Fujisawa Y. Microcystic adnexal carcinoma with large cysts: unusual clinical presentation and histological findings. European journal of dermatology : EJD. 2019.06; 29 (3): 337-339. ( PubMed, DOI )

  143. Nakamura Y, Sasaki K, Fujisawa Y, Okiyama N, Ishitsuka Y, Oya K, Watanabe R, Fujimoto M. Pencil-core granuloma with extensive calcinosis: An unusual case report. The Journal of dermatology. 2019.06; 46 (6): e193-e195. ( PubMed, DOI )

  144. Nakamura Y, Tanaka R, Maruyama H, Ishitsuka Y, Okiyama N, Watanabe R, Fujimoto M, Fujisawa Y. Correlation between blood cell count and outcome of melanoma patients treated with anti-PD-1 antibodies. Japanese journal of clinical oncology. 2019.05; 49 (5): 431-437. ( PubMed, DOI )

  145. Nakamura Y, Fujisawa Y, Ishizuki S, Okiyama N, Ishitsuka Y, Watanabe R, Fujimoto M. Linearly distributed multiple lipomas: An unusual case report. The Journal of dermatology. 2019.05; 46 (5): e175-e176. ( PubMed, DOI )

  146. Nakamura Yoshiyuki, Tanaka Ryota, Maruyama Hiroshi, Ishitsuka Yosuke, Okiyama Naoko, Watanabe Rei, Fujimoto Manabu, Fujisawa Yasuhiro. 抗PD-1抗体で治療された黒色腫患者の血球数と転帰の相関(Correlation between blood cell count and outcome of melanoma patients treated with anti-PD-1 antibodies) Japanese Journal of Clinical Oncology. 2019.05; 49 (5): 431-437. ( ichushi )

  147. Nakamura Y, Watanabe R, Zhenjie Z, Koguchi-Yoshioka H, Vo S, Oya K, Matsumura Y, Tanaka R, Okiyama N, Ishitsuka Y, Fujimoto M, Fujisawa Y. CD103 negative memory T cells may play important roles in making regulatory T-cell-enriched environments in skin tumours. Journal of the European Academy of Dermatology and Venereology : JEADV. 2019.05; 33 (5): e211-e214. ( PubMed, DOI )

  148. Okiyama N, Inoue S, Saito A, Nakamura Y, Ishitsuka Y, Fujisawa Y, Watanabe R, Fujimoto M. Antihelix/helix violaceous macules in Japanese patients with anti-melanoma differentiation-associated protein 5 (MDA5) antibody-associated dermatomyositis. The British journal of dermatology. 2019.05; 180 (5): 1226-1227. ( PubMed, DOI )

  149. Nakamura Yoshiyuki, Fujisawa Yasuhiro, Ishizuki Shoichiro, Okiyama Naoko, Ishitsuka Yosuke, Watanabe Rei, Fujimoto Manabu. 線形に分布した多発脂肪腫　稀な1症例の報告(Linearly distributed multiple lipomas: An unusual case report) The Journal of Dermatology. 2019.05; 46 (5): e175-e176. ( ichushi )

  150. Ogawa T, Okiyama N, Takamuki R, Inoue S, Saito A, Nakamura Y, Ishitsuka Y, Watanabe R, Fujisawa Y, Fujimoto M. Juvenile case of multiple morphea profunda resulting in joint contracture that was successfully treated with cyclosporin A: A case report and review of the published works. The Journal of dermatology. 2019.04; 46 (4): 354-357. ( PubMed, DOI )

  151. Ogawa Tatsuya, Okiyama Naoko, Takamuki Risa, Inoue Sae, Saito Akimasa, Nakamura Yoshiyuki, Ishitsuka Yosuke, Watanabe Rei, Fujisawa Yasuhiro, Fujimoto Manabu. シクロスポリンAによる治療が奏効した、関節拘縮をきたした多発性深部斑状強皮症の若年症例　1症例報告と既報研究のレビュー(Juvenile case of multiple morphea profunda resulting in joint contracture that was successfully treated with cyclosporin A: A case report and review of the published works) The Journal of Dermatology. 2019.04; 46 (4): 354-357. ( ichushi )

  152. Ueda-Hayakawa I, Hamaguchi Y, Okiyama N, Motegi S, Yamaoka T, Miyake S, Higashi A, Okamoto H, Takehara K, Fujimoto M. Autoantibody to transcriptional intermediary factor-1β as a myositis-specific antibody: clinical correlation with clinically amyopathic dermatomyositis or dermatomyositis with mild myopathy. The British journal of dermatology. 2019.04; 180 (4): 881-887. ( PubMed, DOI )

  153. Oya K, Watanabe R, Konishi R, Inoue S, Nakamura Y, Ishitsuka Y, Maruyama H, Okiyama N, Fujisawa Y, Fujimoto M. Possible involvement of IgE antibody in epidermolysis bullosa acquisita: detection and correlation. European journal of dermatology : EJD. 2019.04; 29 (2): 210-212. ( PubMed, DOI )

  154. Nakamura Y, Maruyama H, Fujisawa Y, Inoue S, Okiyama N, Ishitsuka Y, Watanabe R, Fujimoto M. Subungual exostosis with postoperative recurrence followed by spontaneous regression. The Journal of dermatology. 2019.03; 46 (3): e86-e87. ( PubMed, DOI )

  155. Nakamura Yoshiyuki, Maruyama Hiroshi, Fujisawa Yasuhiro, Inoue Sae, Okiyama Naoko, Ishitsuka Yosuke, Watanabe Rei, Fujimoto Manabu. 術後に再発し、その後自然退縮した爪下外骨腫(Subungual exostosis with postoperative recurrence followed by spontaneous regression) The Journal of Dermatology. 2019.03; 46 (3): e86-e87. ( ichushi )

  156. Fujisawa Y, Otomo Y, Ogata Y, Nakamura Y, Fujita R, Ishitsuka Y, Watanabe R, Okiyama N, Ohara K, Fujimoto M. Deep-learning-based, computer-aided classifier developed with a small dataset of clinical images surpasses board-certified dermatologists in skin tumour diagnosis. The British journal of dermatology. 2019.02; 180 (2): 373-381. ( PubMed, DOI )

  157. Shibao Kana, Watanabe Rei, Saito Aki, Ishii Yoshiyuki, Nakamura Yoshiyuki, Ishitsuka Yosuke, Okiyama Naoko, Fujisawa Yasuhiro, Fujimoto Manabu. 意義不明の単クローン性免疫グロブリン血症を伴う粘液水腫性苔癬　日本人患者の症例報告とレビュー(Lichen myxedematosus associated with monoclonal gammopathy of undetermined significance: A case report and a review of Japanese patients) The Journal of Dermatology. 2019.01; 46 (1): e32-e33. ( ichushi )

  158. Koguchi-Yoshioka H, Watanabe R, Fujisawa Y, Ishitsuka Y, Nakamura Y, Okiyama N, Fujimoto M. Skin resident memory T-cell population is not constructed effectively in systemic sclerosis. The British journal of dermatology. 2019.01; 180 (1): 219-220. ( PubMed, DOI )

  159. Shibao K, Watanabe R, Saito A, Ishii Y, Nakamura Y, Ishitsuka Y, Okiyama N, Fujisawa Y, Fujimoto M. Lichen myxedematosus associated with monoclonal gammopathy of undetermined significance: A case report and a review of Japanese patients. The Journal of dermatology. 2019.01; 46 (1): e32-e33. ( PubMed, DOI )

  160. Okiyama N, Fujimoto M. Cutaneous manifestations of dermatomyositis characterized by myositis-specific autoantibodies. F1000Research. 2019; 8 ( PubMed, DOI )

  161. Nakamura Y, Ishitsuka Y, Fujisawa Y, Konishi R, Maruyama H, Inoue S, Okiyama N, Watanabe R, Fujimoto M. Pelvic reactive lymphadenopathy mimicking lymph node metastasis of heel malignant melanoma. European journal of dermatology : EJD. 2018.12; 28 (6): 841-843. ( PubMed, DOI )

  162. Inoue S, Okiyama N, Shobo M, Motegi S, Hirano H, Nakagawa Y, Saito A, Nakamura Y, Ishitsuka Y, Fujisawa Y, Watanabe R, Fujimoto M. Diffuse erythema with 'angel wings' sign in Japanese patients with anti-small ubiquitin-like modifier activating enzyme antibody-associated dermatomyositis. The British journal of dermatology. 2018.12; 179 (6): 1414-1415. ( PubMed, DOI )

  163. Ishitsuka Y, Iwamoto K, Oya K, Nakamura Y, Watanabe R, Okiyama N, Fujisawa Y, Fujimoto M. Pegylated interferon-α2b for local control of Langerhans cell sarcoma. European journal of dermatology : EJD. 2018.12; 28 (6): 835-836. ( PubMed, DOI )

  164. Nakamura Yoshiyuki, Fujisawa Yasuhiro, Tanaka Ryota, Maruyama Hiroshi, Ishitsuka Yosuke, Okiyama Naoko, Watanabe Rei, Fujimoto Manabu. 免疫チェックポイント阻害薬は進行悪性黒色腫患者の日本人集団において全生存期間を延長した　後ろ向き単施設の研究(Use of immune checkpoint inhibitors prolonged overall survival in a Japanese population of advanced malignant melanoma patients: Retrospective single institutional study) The Journal of Dermatology. 2018.11; 45 (11): 1337-1339. ( ichushi )

  165. Nakamura Y, Fujisawa Y, Tanaka R, Maruyama H, Ishitsuka Y, Okiyama N, Watanabe R, Fujimoto M. Use of immune checkpoint inhibitors prolonged overall survival in a Japanese population of advanced malignant melanoma patients: Retrospective single institutional study. The Journal of dermatology. 2018.11; 45 (11): 1337-1339. ( PubMed, DOI )

  166. Nakamura Y, Fujisawa Y, Ishitsuka Y, Tanaka R, Maruyama H, Okiyama N, Watanabe R, Fujimoto M. Negative-pressure closure was superior to tie-over technique for stabilization of split-thickness skin graft in large or muscle-exposing defects: A retrospective study. The Journal of dermatology. 2018.10; 45 (10): 1207-1210. ( PubMed, DOI )

  167. Saito Aki, Okiyama Naoko, Hitomi Shigemi, Anzawa Kazushi, Mochizuki Takashi, Fujimoto Manabu. ボリコナゾール投与が奏効したExophiala lecanii-corniによる皮膚黒色菌糸症(Successful treatment of cutaneous phaeohyphomycosis caused by Exophiala lecanii-corni with voriconazole) The Journal of Dermatology. 2018.10; 45 (10): e271-e272. ( ichushi )

  168. Saito A, Okiyama N, Hitomi S, Anzawa K, Mochizuki T, Fujimoto M. Successful treatment of cutaneous phaeohyphomycosis caused by Exophiala lecanii-corni with voriconazole. The Journal of dermatology. 2018.10; 45 (10): e271-e272. ( PubMed, DOI )

  169. Nakamura Yoshiyuki, Fujisawa Yasuhiro, Ishitsuka Yosuke, Tanaka Ryota, Maruyama Hiroshi, Okiyama Naoko, Watanabe Rei, Fujimoto Manabu. 巨大または筋露出欠損部に対する分層植皮術後の安定化において陰圧閉鎖療法はタイオーバー法よりも優れている　後ろ向き研究(Negative-pressure closure was superior to tie-over technique for stabilization of split-thickness skin graft in large or muscle-exposing defects: A retrospective study) The Journal of Dermatology. 2018.10; 45 (10): 1207-1210. ( ichushi )

  170. Mimura T, Kondo Y, Ohta A, Iwamoto M, Ota A, Okamoto N, Kawaguchi Y, Kono H, Takasaki Y, Takei S, Nishimoto N, Fujimoto M, Asanuma YF, Mimori A, Okiyama N, Kaneko S, Takahashi H, Yokosawa M, Sumida T. Evidence-based clinical practice guideline for adult Still's disease. Modern rheumatology. 2018.09; 28 (5): 736-757. ( PubMed, DOI )

  171. Nakamura Yoshiyuki, Takamuki Risa, Fujisawa Yasuhiro, Okiyama Naoko, Watanabe Rei, Ishitsuka Yosuke, Maruyama Hiroshi, Ishii Yoshiyuki, Fujimoto Manabu. 先天性傍胸骨皮膚洞　1症例報告と既報のレビュー(Congenital peristernal dermal sinus: A case report and published work review) The Journal of Dermatology. 2018.09; 45 (9): e242-e243. ( ichushi )

  172. Mimura Toshihide, Kondo Yuya, Ohta Akihide, Iwamoto Masahiro, Ota Akiko, Okamoto Nami, Kawaguchi Yasushi, Kono Hajime, Takasaki Yoshinari, Takei Shuji, Nishimoto Norihiro, Fujimoto Manabu, Funakubo Asanuma Yu, Mimori Akio, Okiyama Naoko, Kaneko Shunta, Takahashi Hiroyuki, Yokosawa Masahiro, Sumida Takayuki, Health and Labour Sciences Research Grants for research on intractable diseases(The Research Team for Autoimmune Diseases) from the Ministry of Health, Labour, and Welfare of Japan. 成人スチル病診療ガイドライン(Evidence-based clinical practice guideline for adult Still's disease) Modern Rheumatology. 2018.09; 28 (5): 736-757. ( ichushi )

  173. Saito A, Okiyama N, Kubota N, Nakamura Y, Fujisawa Y, Watanabe R, Ishitsuka Y, Bleackley RC, Fujimoto M. Blockade of Granzyme B Remarkably Improves Mucocutaneous Diseases with Keratinocyte Death in Interface Dermatitis. The Journal of investigative dermatology. 2018.09; 138 (9): 2079-2083. ( PubMed, DOI )

  174. Nakamura Y, Takamuki R, Fujisawa Y, Okiyama N, Watanabe R, Ishitsuka Y, Maruyama H, Ishii Y, Fujimoto M. Congenital peristernal dermal sinus: A case report and published work review. The Journal of dermatology. 2018.09; 45 (9): e242-e243. ( PubMed, DOI )

  175. Oya K, Nakamura Y, Fujisawa Y, Okiyama N, Watanabe R, Ishitsuka Y, Maruyama H, Ishii Y, Fujimoto M. Tufted angioma of the finger: A case of an uncommon location with unique dermoscopic features. The Journal of dermatology. 2018.08; 45 (8): e236-e237. ( PubMed, DOI )

  176. Oya Kazumasa, Nakamura Yoshiyuki, Fujisawa Yasuhiro, Okiyama Naoko, Watanabe Rei, Ishitsuka Yosuke, Maruyama Hiroshi, Ishii Yoshiyuki, Fujimoto Manabu. 指趾の房状血管腫　稀な部位における特徴的なダーモスコピー所見を伴う症例(Tufted angioma of the finger: A case of an uncommon location with unique dermoscopic features) The Journal of Dermatology. 2018.08; 45 (8): e236-e237. ( ichushi )

  177. Nakamura Yoshiyuki, Sasaki Katsuhito, Fujisawa Yasuhiro, Okiyama Naoko, Watanabe Rei, Ishitsuka Yosuke, Maruyama Hiroshi, Ishii Yoshiyuki, Fujimoto Manabu. 指趾の粘液嚢腫と後天性爪囲被角線維腫の稀な関連　1症例報告(Unusual association between digital mucous cyst and acquired ungual fibrokeratoma: A case report) The Journal of Dermatology. 2018.08; 45 (8): e234-e235. ( ichushi )

  178. Saito A, Fujisawa Y, Maruyama H, Nakamura Y, Ishitsuka Y, Watanabe R, Okiyama N, Fujimoto M. Subungual melanoma complicated by hydroxyurea-induced melanonychia with non-melanoma Hutchinson's sign. European journal of dermatology : EJD. 2018.08; 28 (4): 559-561. ( PubMed, DOI )

  179. Nakamura Y, Saito A, Takamuki R, Inoue S, Fujisawa Y, Okiyama N, Watanabe R, Ishitsuka Y, Maruyama H, Ishii Y, Fujimoto M. Trichostasis spinulosa arising in isolated collagenoma of the scalp. European journal of dermatology : EJD. 2018.08; 28 (4): 531-532. ( PubMed, DOI )

  180. Nakamura Y, Sasaki K, Fujisawa Y, Okiyama N, Watanabe R, Ishitsuka Y, Maruyama H, Ishii Y, Fujimoto M. Unusual association between digital mucous cyst and acquired ungual fibrokeratoma: A case report. The Journal of dermatology. 2018.08; 45 (8): e234-e235. ( PubMed, DOI )

  181. Saito A, Okiyama N, Iwamoto K, Inoue S, Koguchi-Yoshioka H, Fujimoto M. Case with anaphylactic shock induced by heparin-lock flush injection. The Journal of dermatology. 2018.07; 45 (7): e195-e196. ( PubMed, DOI )

  182. Saito Aki, Okiyama Naoko, Iwamoto Kazuyo, Inoue Sae, Koguchi-Yoshioka Hanako, Fujimoto Manabu. ヘパリンロックフラッシュ注入によりアナフィラキシーショックが誘発された1例(Case with anaphylactic shock induced by heparin-lock flush injection) The Journal of Dermatology. 2018.07; 45 (7): e195-e196. ( ichushi )

  183. Iwamoto K, Fujisawa Y, Ishitsuka Y, Maruyama H, Nakamura Y, Okiyama N, Watanabe R, Fujimoto M. A case of cutaneous angiosarcoma successfully treated with eribulin. European journal of dermatology : EJD. 2018.06; 28 (3): 410-412. ( PubMed, DOI )

  184. Iwamoto K, Nakamura Y, Fujisawa Y, Okiyama N, Watanabe R, Ishitsuka Y, Maruyama H, Ishii Y, Fujimoto M. Depigmented extramammary Paget's disease without histological dermal invasion identified by multiple inguinal and pelvic lymph node metastases. European journal of dermatology : EJD. 2018.06; 28 (3): 387-388. ( PubMed, DOI )

  185. Nakamura Y, Fujisawa Y, Okiyama N, Watanabe R, Tanaka R, Ishitsuka Y, Fujimoto M, Tahara H. Reply: Lymph stasis promotes tumor growth. Journal of dermatological science. 2018.06; 90 (3): 367-368. ( PubMed, DOI )

  186. Saito A, Okiyama N, Tanaka R, Maruyama H, Fujimoto M. A Case of Refractory Subcutaneous Panniculitis-like T-cell Lymphoma with Bone Marrow and Lung Involvement Treated Successfully with Oral Etoposide. Acta dermato-venereologica. 2018.06; 98 (6): 610-611. ( PubMed, DOI )

  187. Oya K, Watanabe R, Inoue S, Obara N, Kiyoki Y, Sakata-Yanagimoto M, Chiba S, Saito C, Matsumura Y, Nakamura Y, Ishitsuka Y, Maruyama H, Okiyama N, Fujisawa Y, Fujimoto M. Bullous pemphigoid accompanied by IgA nephropathy and atypical haemolytic uraemic syndrome. European journal of dermatology : EJD. 2018.06; 28 (3): 421-422. ( PubMed, DOI )

  188. Nakamura Y, Iwamoto K, Fujisawa Y, Okiyama N, Watanabe R, Ishitsuka Y, Maruyama H, Ishii Y, Kondo Y, Sakashita S, Fujimoto M. Multiple haemangiomas in TAFRO syndrome with atypical features of glomeruloid and epithelioid haemangiomas. European journal of dermatology : EJD. 2018.06; 28 (3): 371-372. ( PubMed, DOI )

  189. Nakamura Yoshiyuki, Fujisawa Yasuhiro, Okiyama Naoko, Watanabe Rei, Tanaka Ryota, Ishitsuka Yosuke, Fujimoto Manabu, Tahara Hideaki. 返信「リンパ鬱滞は腫瘍増殖を促進する」(Reply: Lymph stasis promotes tumor growth) Journal of Dermatological Science. 2018.06; 90 (3): 367-368. ( ichushi )

  190. Okiyama N, Asano Y, Hamaguchi Y, Jinnin M, Motegi SI, Koizumi H, Hasegawa M, Ishikawa O, Sato S, Takehara K, Yamamoto T, Fujimoto M, Ihn H. Impact of a new simplified disability scoring system for adult patients with localized scleroderma. The Journal of dermatology. 2018.04; 45 (4): 431-435. ( PubMed, DOI )

  191. Okiyama Naoko, Asano Yoshihide, Hamaguchi Yasuhito, Jinnin Masatoshi, Motegi Sei-ichiro, Koizumi Haruka, Hasegawa Minoru, Ishikawa Osamu, Sato Shinichi, Takehara Kazuhiko, Yamamoto Toshiyuki, Fujimoto Manabu, Ihn Hironobu. 限局性強皮症成人患者に対する新規簡易障害評価システムの影響(Impact of a new simplified disability scoring system for adult patients with localized scleroderma) The Journal of Dermatology. 2018.04; 45 (4): 431-435. ( ichushi )

  192. Nakamura Y, Fujisawa Y, Okiyama N, Watanabe R, Tanaka R, Ishitsuka Y, Tahara H, Fujimoto M. Surgical damage to the lymphatic system promotes tumor growth via impaired adaptive immune response. Journal of dermatological science. 2018.04; 90 (1): 46-51. ( PubMed, DOI )

  193. Nakamura Yoshiyuki, Fujisawa Yasuhiro, Okiyama Naoko, Watanabe Rei, Tanaka Ryota, Ishitsuka Yosuke, Tahara Hideaki, Fujimoto Manabu. 手術によるリンパ系の損傷は、適応免疫応答を損なうことで腫瘍増殖を促進する(Surgical damage to the lymphatic system promotes tumor growth via impaired adaptive immune response) Journal of Dermatological Science. 2018.04; 90 (1): 46-51. ( ichushi )

  194. Oya K, Nakamura Y, Fujisawa Y, Endo R, Tanaka R, Ishitsuka Y, Maruyama H, Watanabe R, Okiyama N, Fujimoto M. Third-line pembrolizumab-induced immune-related interstitial pneumonitis after ipilimumab and nivolumab failure. European journal of dermatology : EJD. 2018.02; 28 (1): 129-130. ( PubMed, DOI )

  195. Fujisawa Y, Yoshino K, Fujimura T, Nakamura Y, Okiyama N, Ishitsuka Y, Watanabe R, Fujimoto M. Cutaneous Angiosarcoma: The Possibility of New Treatment Options Especially for Patients with Large Primary Tumor. Frontiers in oncology. 2018; 8 46. ( PubMed, DOI )

  196. Inoue Sae, Furuta Jun-ichi, Fujisawa Yasuhiro, Onizawa Saori, Ito Shusaku, Sakiyama Masayuki, Kobayashi Keiko, Kanou Toshiyuki, Iijima Shigeruko, Ohi Tsunao, Okubo Chimaki, Moriyama Yoshihiro, Okiyama Naoko, Fujimoto Manabu. 日本人患者における壊疽性膿皮症とその基礎疾患　地域長期研究(Pyoderma gangrenosum and underlying diseases in Japanese patients: A regional long-term study) The Journal of Dermatology. 2017.11; 44 (11): 1281-1284. ( ichushi )

  197. Koguchi-Yoshioka H, Okiyama N, Iwamoto K, Matsumura Y, Ogawa T, Inoue S, Watanabe R, Fujimoto M. Intravenous immunoglobulin contributes to the control of antimelanoma differentiation-associated protein 5 antibody-associated dermatomyositis with palmar violaceous macules/papules. The British journal of dermatology. 2017.11; 177 (5): 1442-1446. ( PubMed, DOI )

  198. Inoue S, Furuta JI, Fujisawa Y, Onizawa S, Ito S, Sakiyama M, Kobayashi K, Kanou T, Iijima S, Ohi T, Okubo C, Moriyama Y, Okiyama N, Fujimoto M. Pyoderma gangrenosum and underlying diseases in Japanese patients: A regional long-term study. The Journal of dermatology. 2017.11; 44 (11): 1281-1284. ( PubMed, DOI )

  199. Ogawa T, Okiyama N, Koguchi-Yoshioka H, Fujimoto M. Eosinophilic granulomatosis with polyangiitis followed by venous thromboembolism resulting in severe cutaneous ulcers. The Journal of dermatology. 2017.09; 44 (9): e216-e217. ( PubMed, DOI )

  200. Ogawa Tatsuya, Okiyama Naoko, Koguchi-Yoshioka Hanako, Fujimoto Manabu. 好酸球性多発血管炎性肉芽腫症に続発し、重度皮膚潰瘍を引き起こす静脈血栓塞栓症(Eosinophilic granulomatosis with polyangiitis followed by venous thromboembolism resulting in severe cutaneous ulcers) The Journal of Dermatology. 2017.09; 44 (9): e216-e217. ( ichushi )

  201. Shibao K, Fujisawa Y, Nakamura Y, Nakamura Y, Maruyama H, Furuta JI, Okiyama N, Ishii Y, Fujimoto M. Behandlung eines kutanen Plattenepithelkarzinoms mit intraarterieller Radiochemotherapie. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 2017.07; 15 (7): 724-726. ( PubMed, DOI )

  202. Hasegawa H, Kawahata K, Mizoguchi F, Okiyama N, Miyasaka N, Kohsaka H. Direct suppression of autoaggressive CD8+ T cells with CD80/86 blockade in CD8+ T cell-mediated polymyositis models of mice. Clinical and experimental rheumatology. 2017.07; 35 (4): 593-597. ( PubMed )

  203. Shibao K, Fujisawa Y, Nakamura Y, Nakamura Y, Maruyama H, Furuta JI, Okiyama N, Ishii Y, Fujimoto M. Cutaneous squamous cell carcinoma treated with preoperative intraarterial chemoradiation therapy. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 2017.07; 15 (7): 724-726. ( PubMed, DOI )

  204. Saito Akimasa, Okiyama Naoko, Saito Koyumi, Tanaka Ryota, Maruyama Hiroshi, Fujimoto Manabu. ダプソンによる治療が奏功した難治性潰瘍形成を伴う顔面深在性エリテマトーデスの1症例(Case of facial lupus erythematosus profundus with intractable ulceration successfully treated with dapsone) The Journal of Dermatology. 2017.05; 44 (5): e89-e90. ( ichushi )

  205. Saito A, Okiyama N, Saito K, Tanaka R, Maruyama H, Fujimoto M. Case of facial lupus erythematosus profundus with intractable ulceration successfully treated with dapsone. The Journal of dermatology. 2017.05; 44 (5): e89-e90. ( PubMed, DOI )

  206. Ogawa Tatsuya, Okiyama Naoko, Koguchi-Yoshioka Hanako, Fujimoto Manabu. タキサン誘発性強皮症様皮膚変化による壊疽　1症例報告(Taxane-induced scleroderma-like skin changes resulting in gangrene: A case report) The Journal of Dermatology. 2017.04; 44 (4): e54-e55. ( ichushi )

  207. Tanaka Ryota, Okiyama Naoko, Okune Mari, Ishitsuka Yosuke, Watanabe Rei, Furuta Junichi, Ohtsuka Mikio, Otsuka Atsushi, Maruyama Hiroshi, Fujisawa Yasuhiro, Fujimoto Manabu. 血清インターロイキン6はニボルマブ関連乾癬様皮膚炎において増加し、腫瘍壊死因子αはニボルマブ反応性のバイオマーカーである(Serum level of interleukin-6 is increased in nivolumab-associated psoriasiform dermatitis and tumor necrosis factor-α is a biomarker of nivolumab recativity) Journal of Dermatological Science. 2017.04; 86 (1): 71-73. ( ichushi )

  208. Tanaka R, Okiyama N, Okune M, Ishitsuka Y, Watanabe R, Furuta J, Ohtsuka M, Otsuka A, Maruyama H, Fujisawa Y, Fujimoto M. Serum level of interleukin-6 is increased in nivolumab-associated psoriasiform dermatitis and tumor necrosis factor-α is a biomarker of nivolumab recativity. Journal of dermatological science. 2017.04; 86 (1): 71-73. ( PubMed, DOI )

  209. Ogawa T, Okiyama N, Koguchi-Yoshioka H, Fujimoto M. Taxane-induced scleroderma-like skin changes resulting in gangrene: A case report. The Journal of dermatology. 2017.04; 44 (4): e54-e55. ( PubMed, DOI )

  210. Inoue Sae, Okiyama Naoko, Okune Mari, Shiraki Nagisa, Kessoku Reiko, Fujimoto Manabu. 本態性血小板血症における分枝状皮斑の臨床的および組織学的特徴　2症例報告と既報のレビュー(Clinical and histological characteristics of livedo racemosa in essential thrombocythemia: A report of two cases and review of the published works) The Journal of Dermatology. 2017.01; 44 (1): 84-87. ( ichushi )

  211. Inoue S, Okiyama N, Okune M, Shiraki N, Kessoku R, Fujimoto M. Clinical and histological characteristics of livedo racemosa in essential thrombocythemia: A report of two cases and review of the published works. The Journal of dermatology. 2017.01; 44 (1): 84-87. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display 】

  1. Oyama Munenori, Ohnuki Yuko, Uruha Akinori, Saito Yoshihiko, Nihimori Yukako, Suzuki Shingo, Inoue Michio, Tanboon Jantima, Okiyama Naoko, Shiina Takashi, Nishino Ichizo, Suzuki Shigeaki. 皮膚筋炎におけるHLA対立遺伝子と自己抗体の密接な関連性(Tight association between HLA alleles and autoantibodies in dermatomyositis). 臨床神経学 2023.09.01

  2. Ichimura Yuki, Konishi Risa, Nomura Toshifumi, Fujimoto Manabu, Okiyama Naoko. Autoimmunity against melanoma differentiation-associated protein 5 induces interstitial lung disease in mice(タイトル和訳中). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  3. Nagashima Natsumi, Ugajin Tsukasa, Miyake Kensuke, Karasuyama Hajime, Namiki Takeshi, Okiyama Naoko. The clinical and histological characteristics of 'basophil-high' atopic dermatitis(タイトル和訳中). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  4. Ebata Satoshi, Yoshizaki Ayumi, Oba Koji, Kashiwabara Kosuke, Ueda Keiko, Uemura Yukari, Watadani Takeyuki, Fukasawa Takemichi, Miura Shunsuke, Yoshizaki-Ogawa Asako, Asano Yoshihide, Okiyama Naoko, Kodera Masanari, Hasegawa Minoru, Sato Shinichi. Safety and efficacy of rituximab in systemic sclerosis (DESIRES): a double-blind, investigator-initiated, randomised, placebo-controlled trial(タイトル和訳中). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  5. Namiki Takeshi, Nojima Kohei, Hayashi Masahiro, Kawaguchi Masakazu, Suzuki Tamio, Ishikawa Masashi, Tanemura Atsushi, Katayama Ichiro, Mori Taisuke, Yamazaki Naoya, Mori Hiroki, Sasaki Yoshiyuki, Yokozeki Hiroo, Okiyama Naoko. Overexpression of NUAK2 and phospho-Akt(S473) has a significant impact on development and progression in acral melanomas(タイトル和訳中). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  6. Iida Tadatsune, Namiki Takeshi, Kobayashi Daisuke, Yokozeki Hiroo, Okiyama Naoko. Macrophage activation promotes hypohidrosis(タイトル和訳中). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  7. Okiyama Naoko. Comprehensive study of autoimmune diseases(タイトル和訳中). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  8. Nagashima Natsumi, Ugajin Tsukasa, Miyake Kensuke, Karasuyama Hajime, Namiki Takeshi, Okiyama Naoko. "好塩基球の多い"アトピー性皮膚炎の臨床的および組織学的特徴(The clinical and histological characteristics of 'basophil-high' atopic dermatitis). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  9. Okiyama Naoko. 自己免疫疾患の包括的研究(Comprehensive study of autoimmune diseases). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  10. Ebata Satoshi, Yoshizaki Ayumi, Oba Koji, Kashiwabara Kosuke, Ueda Keiko, Uemura Yukari, Watadani Takeyuki, Fukasawa Takemichi, Miura Shunsuke, Yoshizaki-Ogawa Asako, Asano Yoshihide, Okiyama Naoko, Kodera Masanari, Hasegawa Minoru, Sato Shinichi. 全身性強皮症におけるリツキシマブの安全性と有効性(DESIRES)　二重盲検、医師主導、無作為化、プラセボ対照試験(Safety and efficacy of rituximab in systemic sclerosis (DESIRES): a double-blind, investigator-initiated, randomised, placebo-controlled trial). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  11. Iida Tadatsune, Namiki Takeshi, Kobayashi Daisuke, Yokozeki Hiroo, Okiyama Naoko. マクロファージの活性化が発汗減少症を促進する(Macrophage activation promotes hypohidrosis). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  12. Namiki Takeshi, Nojima Kohei, Hayashi Masahiro, Kawaguchi Masakazu, Suzuki Tamio, Ishikawa Masashi, Tanemura Atsushi, Katayama Ichiro, Mori Taisuke, Yamazaki Naoya, Mori Hiroki, Sasaki Yoshiyuki, Yokozeki Hiroo, Okiyama Naoko. NUAK2とphospho-Akt(S473)の過剰発現は先端黒色腫の発生と進行に大きな影響を及ぼす(Overexpression of NUAK2 and phospho-Akt(S473) has a significant impact on development and progression in acral melanomas). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  13. Ichimura Yuki, Konishi Risa, Nomura Toshifumi, Fujimoto Manabu, Okiyama Naoko. Melanoma differentiation-associated protein 5に対する自己免疫がマウスの間質性肺疾患を誘発する(Autoimmunity against melanoma differentiation-associated protein 5 induces interstitial lung disease in mice). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  14. Nagashima Natsumi, Ugajin Tsukasa, Miyake Kensuke, Karasuyama Hajime, Namiki Takeshi, Okiyama Naoko. "好塩基球の多い"アトピー性皮膚炎の臨床的および組織学的特徴(The clinical and histological characteristics of 'basophil-high' atopic dermatitis). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  15. Iida Tadatsune, Namiki Takeshi, Kobayashi Daisuke, Yokozeki Hiroo, Okiyama Naoko. マクロファージの活性化が発汗減少症を促進する(Macrophage activation promotes hypohidrosis). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  16. Namiki Takeshi, Nojima Kohei, Hayashi Masahiro, Kawaguchi Masakazu, Suzuki Tamio, Ishikawa Masashi, Tanemura Atsushi, Katayama Ichiro, Mori Taisuke, Yamazaki Naoya, Mori Hiroki, Sasaki Yoshiyuki, Yokozeki Hiroo, Okiyama Naoko. NUAK2とphospho-Akt(S473)の過剰発現は先端黒色腫の発生と進行に大きな影響を及ぼす(Overexpression of NUAK2 and phospho-Akt(S473) has a significant impact on development and progression in acral melanomas). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  17. Ichimura Yuki, Konishi Risa, Nomura Toshifumi, Fujimoto Manabu, Okiyama Naoko. Melanoma differentiation-associated protein 5に対する自己免疫がマウスの間質性肺疾患を誘発する(Autoimmunity against melanoma differentiation-associated protein 5 induces interstitial lung disease in mice). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  18. Ebata Satoshi, Yoshizaki Ayumi, Oba Koji, Kashiwabara Kosuke, Ueda Keiko, Uemura Yukari, Watadani Takeyuki, Fukasawa Takemichi, Miura Shunsuke, Yoshizaki-Ogawa Asako, Asano Yoshihide, Okiyama Naoko, Kodera Masanari, Hasegawa Minoru, Sato Shinichi. 全身性強皮症におけるリツキシマブの安全性と有効性(DESIRES)　二重盲検、医師主導、無作為化、プラセボ対照試験(Safety and efficacy of rituximab in systemic sclerosis (DESIRES): a double-blind, investigator-initiated, randomised, placebo-controlled trial). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  19. Okiyama Naoko. 自己免疫疾患の包括的研究(Comprehensive study of autoimmune diseases). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  20. Nagashima Natsumi, Ugajin Tsukasa, Miyake Kensuke, Karasuyama Hajime, Namiki Takeshi, Okiyama Naoko. "好塩基球の多い"アトピー性皮膚炎の臨床的および組織学的特徴(The clinical and histological characteristics of 'basophil-high' atopic dermatitis). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  21. Okiyama Naoko. 自己免疫疾患の包括的研究(Comprehensive study of autoimmune diseases). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  22. Ebata Satoshi, Yoshizaki Ayumi, Oba Koji, Kashiwabara Kosuke, Ueda Keiko, Uemura Yukari, Watadani Takeyuki, Fukasawa Takemichi, Miura Shunsuke, Yoshizaki-Ogawa Asako, Asano Yoshihide, Okiyama Naoko, Kodera Masanari, Hasegawa Minoru, Sato Shinichi. 全身性強皮症におけるリツキシマブの安全性と有効性(DESIRES)　二重盲検、医師主導、無作為化、プラセボ対照試験(Safety and efficacy of rituximab in systemic sclerosis (DESIRES): a double-blind, investigator-initiated, randomised, placebo-controlled trial). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  23. Iida Tadatsune, Namiki Takeshi, Kobayashi Daisuke, Yokozeki Hiroo, Okiyama Naoko. マクロファージの活性化が発汗減少症を促進する(Macrophage activation promotes hypohidrosis). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  24. Namiki Takeshi, Nojima Kohei, Hayashi Masahiro, Kawaguchi Masakazu, Suzuki Tamio, Ishikawa Masashi, Tanemura Atsushi, Katayama Ichiro, Mori Taisuke, Yamazaki Naoya, Mori Hiroki, Sasaki Yoshiyuki, Yokozeki Hiroo, Okiyama Naoko. NUAK2とphospho-Akt(S473)の過剰発現は先端黒色腫の発生と進行に大きな影響を及ぼす(Overexpression of NUAK2 and phospho-Akt(S473) has a significant impact on development and progression in acral melanomas). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  25. Ichimura Yuki, Konishi Risa, Nomura Toshifumi, Fujimoto Manabu, Okiyama Naoko. Melanoma differentiation-associated protein 5に対する自己免疫がマウスの間質性肺疾患を誘発する(Autoimmunity against melanoma differentiation-associated protein 5 induces interstitial lung disease in mice). 日本研究皮膚科学会年次学術大会・総会プログラム 2022.10.01

  26. Ichimura Yuki, Konishi Risa, Tanaka Ryota, Kubota Noriko, Ishitsuki Shoichiro, Sasaki Katsuhito, Nakamura Yasuyuki, Fujisawa Yasuhiro, Nomura Toshifumi, Watanabe Hideki, Okiyama Naoko. 内因性グランザイムB阻害剤であるセリンプロテアーゼ阻害剤A3nはヒト皮膚における移植片対宿主病の反応を緩和する(Serine protease inhibitor A3n, an endogenous granzyme B inhibitor, alleviates graft-versus-host disease reaction in human skin). 日本研究皮膚科学会年次学術大会・総会プログラム 2021.12.01

  27. Oya Kazumasa, Nakamura Yoshiyuki, Fujisawa Yasuhiro, Okiyama Naoko, Fujimoto Manabu, Nomura Toshifumi. 外用イミキモドと抗PD-1抗体の併用による有意に強力な抗腫瘍効果(Combination treatment of topical imiquimod plus anti-programmed cell death 1 antibody exerts significantly potent antitumor effect). 日本研究皮膚科学会年次学術大会・総会プログラム 2021.12.01

  28. Kubota Noriko, Tanaka Ryota, Ichimura Yuki, Konishi Risa, Tso J Yun, Tsurushita Naoya, Nomura Toshifumi, Okiyama Naoko. 皮膚常在性メモリーT細胞上のCD122阻害は粘膜皮膚の移植片対宿主病の発症を抑制する(Blockade of CD122 on skin resident memory T cells suppresses the development of mucocutaneous graft-versus-host disease). 日本研究皮膚科学会年次学術大会・総会プログラム 2021.12.01

  29. Okiyama Naoko. 皮膚科領域における自己免疫機構(Autoimmune mechanisms in dermatology). 日本研究皮膚科学会年次学術大会・総会プログラム 2021.12.01

  30. Tanaka Ryota, Ichimura Yuki, Kubota Noriko, Nakamura Yoshiyuki, Ishitsuka Yosuke, Watanabe Rei, Fujisawa Yasuhiro, Mizuno Seiya, Takahashi Satoru, Fujimoto Manabu, Nomura Toshifumi, Okiyama Naoko. Differential involvement of programmed cell death ligands in skin immune responses(和訳中). 日本免疫学会総会・学術集会記録 2021.11.01

  31. Kubota Noriko, Tanaka Ryota, Nakamura Yoshiyuki, Clausen Bjoern E., Fujimoto Manabu, Okiyama Naoko. Langerhans cells suppress the population of pathogenic CD8+ T cells in situ during mucocutaneous acutegraft-versus host disease(和訳中). 日本免疫学会総会・学術集会記録 2021.11.01

  32. Kubota Noriko, Tanaka Ryota, Nakamura Yoshiyuki, Clausen Bjoern E., Fujimoto Manabu, Okiyama Naoko. ランゲルハンス細胞による粘膜皮膚急性移植片対宿主病における病原性CD8+T細胞集団のin situでの抑制(Langerhans cells suppress the population of pathogenic CD8+ T cells in situ during mucocutaneous acutegraft-versus host disease). 日本免疫学会総会・学術集会記録 2021.11.01

  33. Tanaka Ryota, Ichimura Yuki, Kubota Noriko, Nakamura Yoshiyuki, Ishitsuka Yosuke, Watanabe Rei, Fujisawa Yasuhiro, Mizuno Seiya, Takahashi Satoru, Fujimoto Manabu, Nomura Toshifumi, Okiyama Naoko. 皮膚免疫応答におけるプログラム細胞死リガンドの関与の違い(Differential involvement of programmed cell death ligands in skin immune responses). 日本免疫学会総会・学術集会記録 2021.11.01

  34. Kubota Noriko, Tanaka Ryota, Nakamura Yoshiyuki, Clausen Bjoern E., Fujimoto Manabu, Okiyama Naoko. ランゲルハンス細胞による粘膜皮膚急性移植片対宿主病における病原性CD8+T細胞集団のin situでの抑制(Langerhans cells suppress the population of pathogenic CD8+ T cells in situ during mucocutaneous acutegraft-versus host disease). 日本免疫学会総会・学術集会記録 2021.11.01

  35. Tanaka Ryota, Ichimura Yuki, Kubota Noriko, Nakamura Yoshiyuki, Ishitsuka Yosuke, Watanabe Rei, Fujisawa Yasuhiro, Mizuno Seiya, Takahashi Satoru, Fujimoto Manabu, Nomura Toshifumi, Okiyama Naoko. 皮膚免疫応答におけるプログラム細胞死リガンドの関与の違い(Differential involvement of programmed cell death ligands in skin immune responses). 日本免疫学会総会・学術集会記録 2021.11.01

  36. Tanaka Ryota, Ichimura Yuki, Kubota Noriko, Nakamura Yoshiyuki, Ishitsuka Yosuke, Watanabe Rei, Fujisawa Yasuhiro, Mizuno Seiya, Takahashi Satoru, Fujimoto Manabu, Nomura Toshifumi, Okiyama Naoko. 皮膚免疫応答におけるプログラム細胞死リガンドの関与の違い(Differential involvement of programmed cell death ligands in skin immune responses). 日本免疫学会総会・学術集会記録 2021.11.01

  37. Kubota Noriko, Tanaka Ryota, Nakamura Yoshiyuki, Clausen Bjoern E., Fujimoto Manabu, Okiyama Naoko. ランゲルハンス細胞による粘膜皮膚急性移植片対宿主病における病原性CD8+T細胞集団のin situでの抑制(Langerhans cells suppress the population of pathogenic CD8+ T cells in situ during mucocutaneous acutegraft-versus host disease). 日本免疫学会総会・学術集会記録 2021.11.01

  38. Kubota Noriko, Tanaka Ryota, Nakamura Yoshiyuki, Clausen Bjoern E., Fujimoto Manabu, Okiyama Naoko. ランゲルハンス細胞による粘膜皮膚急性移植片対宿主病における病原性CD8+T細胞集団のin situでの抑制(Langerhans cells suppress the population of pathogenic CD8+ T cells in situ during mucocutaneous acutegraft-versus host disease). 日本免疫学会総会・学術集会記録 2021.11.01

  39. Tanaka Ryota, Ichimura Yuki, Kubota Noriko, Nakamura Yoshiyuki, Ishitsuka Yosuke, Watanabe Rei, Fujisawa Yasuhiro, Mizuno Seiya, Takahashi Satoru, Fujimoto Manabu, Nomura Toshifumi, Okiyama Naoko. 皮膚免疫応答におけるプログラム細胞死リガンドの関与の違い(Differential involvement of programmed cell death ligands in skin immune responses). 日本免疫学会総会・学術集会記録 2021.11.01

  40. Kubota Noriko, Tanaka Ryota, Nakamura Yoshiyuki, Clausen Bjoern E., Fujimoto Manabu, Okiyama Naoko. ランゲルハンス細胞による粘膜皮膚急性移植片対宿主病における病原性CD8+T細胞集団のin situでの抑制(Langerhans cells suppress the population of pathogenic CD8+ T cells in situ during mucocutaneous acutegraft-versus host disease). 日本免疫学会総会・学術集会記録 2021.11.01

  41. Kubota Noriko, Tanaka Ryota, Nakamura Yoshiyuki, Clausen Bjoern E., Fujimoto Manabu, Okiyama Naoko. ランゲルハンス細胞による粘膜皮膚急性移植片対宿主病における病原性CD8+T細胞集団のin situでの抑制(Langerhans cells suppress the population of pathogenic CD8+ T cells in situ during mucocutaneous acutegraft-versus host disease). 日本免疫学会総会・学術集会記録 2021.11.01

  42. Tanaka Ryota, Ichimura Yuki, Kubota Noriko, Nakamura Yoshiyuki, Ishitsuka Yosuke, Watanabe Rei, Fujisawa Yasuhiro, Mizuno Seiya, Takahashi Satoru, Fujimoto Manabu, Nomura Toshifumi, Okiyama Naoko. 皮膚免疫応答におけるプログラム細胞死リガンドの関与の違い(Differential involvement of programmed cell death ligands in skin immune responses). 日本免疫学会総会・学術集会記録 2021.11.01

  43. Komura Kazuhiro, Okiyama Naoko, Watanabe Kazuyoshi. COVID toesの一例(A case of COVID toes). 日本皮膚科学会雑誌 2021.05.01

  44. Ichimura Yuki, Inoue Michio, Nishino Ichizo, Fujimoto Manabu, Nomura Toshifumi, Okiyama Naoko. 日本における抗NXP2抗体陽性多発性筋炎/皮膚筋炎の臨床的特徴(Clinical features of anti-NXP2 antibody-positive polymyositis/dermatomyositis in Japan). 日本皮膚科学会雑誌 2021.05.01

  45. Ichimura Yuki, Okiyama Naoko. 自己抗体　多様な免疫学的検査における抗核マトリクスタンパク質2抗体の診断精度(Autoantibody　Diagnostic accuracy of anti-nuclear matrix protein 2 antibody in various immunological assays). 日本リウマチ学会総会・学術集会プログラム・抄録集 2021.03.01

  46. Tanaka Ryota, Ichimura Yuki, Kubota Noriko, Saito Akimasa, Mizuno Seiya, Takahashi Satoshi, Fujimoto Manabu, Okiyama Naoko. Langerhans細胞に発現するPD-L1はイミキモド誘発乾癬様皮膚炎を負に調節する(PD-L1 expressed on Langerhans cell negatively regulates imiquimod-induced psoriasis-like dermatitis). 日本研究皮膚科学会年次学術大会・総会プログラム 2020.11.01

  47. Koguchi-Yoshioka Hanako, Watanabe Rei, Matsumura Yutaka, Okiyama Naoko, Fujisawa Yasuhiro, Fujimoto Manabu. グランザイムB産生常在型メモリーT細胞と円形脱毛症の予後とが関連する可能性(The possible linkage of granzyme B-producing resident memory T cells with the disease prognosis of alopecia areata). 日本研究皮膚科学会年次学術大会・総会プログラム 2020.11.01

  48. Okiyama Naoko, Igawa Ken. デュピルマブで難治の顔面皮疹に対しケトコナゾール局所治療が奏功したアトピー性皮膚炎症例(Successful topical treatment with ketoconazole for facial rashes refractory to dupilumab in patients with atopic dermatitis). アレルギー 2020.10.01

  49. Ichimura Yuki, Fujimoto Manabu, Okiyama Naoko. Autoantibodies　抗MDA5抗体陽性間質性肺疾患の新規マウスモデルの構築(Establishment of a new murine model for anti-melanoma differentiation-associated gene 5 antibody-associated interstitial lung disease). 日本リウマチ学会総会・学術集会プログラム・抄録集 2020.08.01

  50. Tanaka Ryota, Ichimura Yuki, Kubota Noriko, Fujimoto Manabu, Okiyama Naoko. 免疫の種類に基づいたプログラム細胞死リガンド1および2の役割の違い(Distinct roles of programmed cell death ligands 1 and 2 based on the type of immunity). 日本研究皮膚科学会年次学術大会・総会プログラム 2019.10.01

  51. Koguchi-Yoshioka Hanako, Hoffer Elena, Cheuk Stanley, Matsumura Yutaka, Vo Sa, Nakamura Yoshiyuki, Ishitsuka Yosuke, Okiyama Naoko, Fujisawa Yasuhiro, Fujimoto Manabu, Eidsmo Liv, Clark Rachael A., Watanabe Rei. 高齢者における皮膚T細胞の多様性と機能の維持(Remained diversity and function in older individuals in skin T cell). 日本研究皮膚科学会年次学術大会・総会プログラム 2019.10.01

  52. Saito Akimasa, Inoue Sae, Nakamura Yoshiyuki, Watanabe Rei, Fujisawa Yasuhiro, Nakano Hajime, Fujimoto Manabu, Okiyama Naoko. 骨髄性プロトポルフィリン症の日本人患者における新規ナンセンス変異(Novel non-sense mutation in a Japanese patient with erythropoietic protoporphyria). 日本皮膚科学会雑誌 2019.05.01

  53. Okiyama Naoko, Fujimoto Manabu. マウスでは皮膚筋炎特異的自己抗原転写中間因子(TIF1)-γの免疫化により筋炎が誘発される(Immunization of dermatomyositis-specific autoantigen transcriptional intermediary factor(TIF1)-γinduces myositis in mice). 日本研究皮膚科学会年次学術大会・総会プログラム 2017.11.01

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Awards & Honors 【 display / non-display 】

  • Japanese Society of Investigative Dermatology Award，2021

  • The Albert M. Kligman Travel Fellowships，Society for Investigative Dermatology，2012

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Others 【 display / non-display 】

  • Successful murine model of dermatomyositis reveals underlying immune system involvement ，2024.04

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