Graduating School 【 display / non-display

  • Okayama University, Faculty of Dentistry, 1990.03, Graduated

Campus Career 【 display / non-display

  • 2021.04
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Division of Oral Health Sciences, Department of Dental Anesthesiology and Orofacial Pain Management, Professor

External Career 【 display / non-display

  • 1993.01
    , Assistant Professor
  • 1999.08
    , Junior Associate Professor
  • 2007.11
    , Associate Professor

Research Areas 【 display / non-display

  • Surgical dentistry

  • Social dentistry


Published Papers & Misc 【 display / non-display

  1. Asano Sayaka, Hirotoshi Yamamoto, Shigeru Maeda. Factors Affecting Intraoperative Blood Loss in Orthognathic Surgery: A Monocentric Retrospective Study The Journal of the Stomatological Society, Japan. 2024; in press

  2. Saki Okabe, Yasuhiro Nakagawa, Yu Sato, Ryo Wakita, Shigeru Maeda, Toshiyuki Ikoma. Preparation and Drug Release Properties of Poly(lactic-co-glycolic acid) Microparticles Co-encapsulating Dual Drugs, Lidocaine and Capsaicin The Journal of the Stomatological Society, Japan. 2024; in press

  3. Ryo Wakita, Yukiko BaBa, Haruhisa Fukayama, Shigeru Maeda. Factors associated with transient bradycardia during local anesthesia administration to the oral cavity under intravenous sedation: A retrospective cohort study Journal of Dental Sciences. 2023.08; ( DOI )

  4. Takaya Ito, Nozomi Utsumi, Yukiko Baba, Tomoka Matsumura, Ryo Wakita, Shigeru Maeda. Considerations for Satisfactory Sedation during Dental Implant Surgery Journal of Personalized Medicine. 2023.02; 13 (3): 461. ( DOI )

  5. Ken Takahashi,Yasuhiro Nakagawa, Yu Sato, Ryo Wakita, Maeda Shigeru, Toshiyuki Ikoma. pH-responsive release of anesthetic lidocaine derivative QX-OH from mesoporous silica nanoparticles mediated by ester bonds Journal of Drug Delivery Science and Technology. 2022.12; 78 ( DOI )

  6. Budiman Hilmanda, Wakita Ryo, Ito Takaya, Maeda Shigeru. Factors Associated with Variability in Pulse Wave Transit Time Using Pulse Oximetry: A Retrospective Study JOURNAL OF CLINICAL MEDICINE. 2022.07; 11 (14): ( PubMed, DOI )

  7. Shinji Kurata, Takuro Sanuki, Hitoshi Higuchi, Takuya Miyawaki, Seiji Watanabe, Shigeru Maeda, Shuntaro Sato, Max Pinkham, Stanislav Tatkov, Takao Ayuse. The clinical advantage of nasal high-flow in respiratory management during procedural sedation: A scoping review on the application of nasal high-flow during dental procedures with sedation Japanese Dental Science Review. 2022.06; 58 179-182. ( DOI )

  8. Kay Thwe Ye Min Soe, Hiroyuki Ishiyama, Akira Nishiyama, Masahiko Shimada, Shigeru Maeda . Effect of Different Maxillary Oral Appliance Designs on Respiratory Variables during Sleep International Journal of Environmental Research and Public Health. 2022.05; 19 (11): 6714. ( DOI )

  9. Matsumura T, Hosokawa S, Hanaoka M, Abe Y, Iwamoto T, Maeda S. Transient ventricular bigeminy during emergence from general anesthesia in a pediatric patient with catecholaminergic polymorphic ventricular tachycardia. Journal of electrocardiology. 2022.05; 73 38-41. ( PubMed, DOI )

  10. Tomoko Higashi, Naomichi Murata, Maki Fujimoto, Saki Miyake, Masahiko Egusa, Hitoshi Higuchi, Shigeru Maeda, Takuya Miyawaki. Capsaicin may improve swallowing impairment in patients with amyotrophic lateral sclerosis: a randomized controlled trial Acta Medica Okayama. 2022.04; 76 (2): 179-186. ( PubMed, DOI )

  11. Yukiko Baba, Ryo Wakita, Takeshi Kuroshima, Toshimitsu Ohsako, Shigeru Maeda. Partial glossectomy under general anesthesia in two pregnant women with mild respiratory episodes Advances in Oral and Maxillofacial Surgery. 2022.03; 6 100279. ( DOI )

  12. Yu Sato, Tomoka Matsumura, Yushi Abe, Chihiro Kutsumizu, Shigeru Maeda. Coronary Spasm During Postoperative Sedation with Dexmedetomidine Anesthesia Progress . 2021.12; 69 (3): 20-24. ( DOI )

  13. Higuchi H, Takaya-Ishida K, Miyake S, Fujimoto M, Nishioka Y, Maeda S, Miyawaki T. Comparison of Oxygen Saturation Between Nasal High-Flow Oxygen and Conventional Nasal Cannula in Obese Patients Undergoing Dental Procedures With Deep Sedation: A Randomized Crossover Trial. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. 2021.04; ( PubMed, DOI )

  14. Fujimoto M, Higuchi H, Honda-Wakasugi Y, Miyake S, Nishioka Y, Yabuki-Kawase A, Maeda S, Miyawaki T. Dexmedetomidine inhibits LPS-induced inflammatory responses through peroxisome proliferator-activated receptor gamma (PPARγ) activation following binding to α<sub>2</sub> adrenoceptors. European journal of pharmacology. 2021.02; 892 173733. ( PubMed, DOI )

  15. Hayashi R, Maeda S, Hideki T, Higuchi H, Miyawaki T. Pulmonary Aspiration During Induction of General Anesthesia Anesth Prog. 2020 Dec 1;67(4):214-218. . 2020.12; 67 (4): 214-218. ( PubMed, DOI )

  16. Maeda S, Higuchi H, Fujimoto M, Miyake S, Honda-Wakasugi Y, Miyawaki T. Assessing the Effectiveness of Combined Analgesics for Bilateral Ramus Osteotomies. Anesthesia progress. 2020.09; 67 (3): 140-145. ( PubMed, DOI )

  17. Furuya T, Inoue E, Tanaka E, Maeda S, Ikari K, Taniguchi A, Yamanaka H. Age and female gender associated with periodontal disease in Japanese patients with rheumatoid arthritis: Results from self-reported questionnaires from the IORRA cohort study. Modern rheumatology. 2020.05; 30 (3): 465-470. ( PubMed, DOI )

  18. Kodama M, Higuchi H, Ishii-Maruhama M, Nakano M, Honda-Wakasugi Y, Maeda S, Miyawaki T. Multi-drug therapy for epilepsy influenced bispectral index after a bolus propofol administration without affecting propofol's pharmacokinetics: a prospective cohort study. Scientific reports. 2020.01; 10 (1): 1578. ( PubMed, DOI )

  19. Miyake S, Higuchi H, Honda-Wakasugi Y, Fujimoto M, Kawai H, Nagatsuka H, Maeda S, Miyawaki T. Locally injected ivabradine inhibits carrageenan-induced pain and inflammatory responses via hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. PloS one. 2019; 14 (5): e0217209. ( PubMed, DOI )

  20. Ishii-Maruhama M, Higuchi H, Nakanou M, Honda-Wakasugi Y, Yabuki-Kawase A, Maeda S, Miyawaki T. In vitro changes in the proportion of protein-unbound-free propofol induced by valproate. Journal of anesthesia. 2018.10; 32 (5): 688-693. ( PubMed, DOI )

  21. Maeda S, Andoh T, Onishi R, Tomoyasu Y, Higuchi H, Miyawaki T. Remifentanil suppresses increase in interleukin-6 mRNA in the brain by inhibiting cyclic AMP synthesis. Journal of anesthesia. 2018.10; 32 (5): 731-739. ( PubMed, DOI )

  22. Higuchi H, Maeda S, Ishii-Maruhama M, Honda-Wakasugi Y, Yabuki-Kawase A, Miyawaki T. Intellectual disability is a risk factor for delayed emergence from total intravenous anaesthesia. J Intellect Disabil Res. 2017.11; 62 (3): 217-224. ( DOI )

  23. Furuya Takefumi, Maeda Shigeru, Momohara Shigeki, Taniguchi Atsuo, Yamanaka Hisashi. Dental treatments, tooth extractions, and osteonecrosis of the jaw in Japanese patients with rheumatoid arthritis: results from the IORRA cohort study) Journal of Bone and Mineral Metabolism. 2017.05; 35 (3): 344-350. ( DOI )

  24. Maeda S, Honda Y, Tanimura H, Tomoyasu Y, Higuchi H, Murata N, Egusa M, Miyawaki T. Clinical Analysis of Analgesics and Steroids Use for Extraction of Teeth in Patients with Intellectual Disability Under General Anesthesia. The open dentistry journal. 2017; 11 181-186. ( PubMed, DOI )

  25. Takaya K, Higuchi H, Ishii-Maruhama M, Yabuki-Kawase A, Honda Y, Tomoyasu Y, Maeda S, Miyawaki T. Capnography Prevents Hypoxia during Sedation for Dental Treatment: A Randomized Controlled Trial. JDR Clin Trans Res. 2016.10; 2 (2): 158-167. ( DOI )

  26. Maeda S, Tomoyasu Y, Higuchi H, Honda Y, Ishii-Maruhama M, Miyawaki T.. Female patients require a higher propofol infusion rate for sedation. Anesthesia progress. 2016.07; 63 67-70. ( DOI )

  27. Watanabe Y, Higuchi H, Ishii-Maruhama M, Honda Y, Yabuki-Kawase A, Yamane-Hirano A, Tomoyasu Y, Maeda S, Miyazaki T. Effect of low-dose midazolam on high blood pressure in dental patients: a randomized, double-blind, placebo-controlled, multi center study. Brit J Oral Maxillofac Surg. 2016.03; 54 (4): 443-448. ( DOI )

  28. Hayashi T, Higuchi H, Tomoyasu Y, Ishii-Maruhama M, Maeda S, Miyawaki T. Effect of carbamazepine or phenytoin therapy on blood level of intravenously administered-midazolam: a prospective cohort study. Journal of anesthesia. 2015.08; 30 166-169. ( DOI )

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Conference Activities & Talks 【 display / non-display

  1. Takaya Ito, Motoyo Maruyama, Hirotoshi Iwasaki, Yoshitaka Miyagawa, Hidenori Suzuki, Shigeru Maeda, Atsushi Sakai. Involvement of long noncoding RNAs (lnkRNAs) containing ultraconserved regions expressed in primary sensory neurons in a rat neuropathic pain model. Neuroscience 2023 2023.11.15 Washington DC

  2. Ryoko Kurisku, Yoko Yamazaki, Shigeru Maeda. Involvement of Lysophospholipids in trigeminal ganglion in neuropathic pain of orofacial region. Neuroscience 2023 2023.11.14 Washington DC

  3. Shigeru MAEDA. General anesthesia in dentistry for patients with intellectual disabilities. General Meeting of Korean Association for Dentistry and Oral Health 2023.04.16 Seoul

  4. Kurisu Ryoko, Tadashi Saigusa, Yuri Aono, Yoshinori Hayashi, Suzuro Hitomi, Shigeru Maeda, Masahiko Shimada, Koichi Iwata, Masamichi Shinoda. Roles of pannexin 1 in the trigeminal ganglion in orofacial mechanical allodynia following infraorbital nerve injury in rats. The 96th Annual Meeting of the Japanese Pharmacological Society 2022.11.30 Yokohama

  5. Hilmanda, Shigeru Maeda. Factors Associated with Variation in Pulse Wave Transit Time using Pulse Oximetry. 2022.02.19

  6. Tomoka Matsumura, Shigeru Maeda. Lidocaine suppresses cell proliferation and induces apoptosis of myofibroblasts. Neuroscience 2021 2021.11.08 on-line

  7. Maeda S, Miyake S, Fujimoto M, Nishioka Y, Higuchi H, Miyawaki T. Delta Opioid receptor ligand suppresses increase in IL-6 in cultured microglia . IADR 2021.07.22

  8. Maeda S, Miyake S, Fujimoto M, Higuchi H, Miyawaki T. Dexmedetomidine suppresses an increase in IL-6 mRNA in models of perioperative brain ischemia.. 2019.06.19

  9. Fujimoto M, Honda-Wakasugi Y, Yabuki-Kawase A, Higuchi H, Maeda S, Miyawaki T. A muscle relaxant does not necessarily cause trismus in patient with masticatory muscle tendon-aponeurosis hyperplasia. 2018.10.04

  10. Miyake S, Honda-Wakasugi Y, Yabuki-Kawase A, Higuchi H, Maeda S, Miyawaki T. Ivabradine inhibits LPS-stimulated inflammatory cytokine production in the mouse macrophage-like cell line Raw 264.7, but not via HCN-2 and HCN-4 channe. 2018.10.04

  11. Kurita E, Onishi R, Higuchi H, Honda-Wakasugi Y, Yabuki-Kawase A, Maeda S, Miyawaki T. Management of a malignant pheochromocytome patient undergoing oral surgery. 2018.10.04

  12. Maeda S, Onishi R, Honda-Wakasugi Y, Yabuki-Kawase A, Higuchi H, Miyawaki T. Brain protection of dexmedetomidine in perioperative model. 2018.10.04

  13. Nishioka Y, Mori-Yoshioka M, Tanimura H, Honda-Wakasugi Y, Yabuki-Kawase A, Higuchi H, Maeda S, Miyawaki T. Electrical Surface Charge and Encapsulation Efficiency of Midazolam Encapsulating Liposomes. 2018.07.25

  14. Miyake S, Honda-Wakasugi Y, Yabuki-Kawase A, Higuchi H, Miyawaki T. The Inhibitory Effect of Locally Administered Ivabradine on Inflammatory Pain. 2018.07.25

  15. Maeda S, Honda-Wakasugi Y, Miyake S, Nishioka Y, Onishi R, Fujimoto M, Kurita E, Higuchi H, Miyawaki T. Effective Combinations of Analgesics for Ramus Osteotomy. 2018.07.25

  16. Maeda S, Onishi R, Honda-Wakasugi Y, Yabuki-Kawase A, Higuchi H, Miyawaki T. Effects of dexmedetomidine on brain ischemia. 2017.11.11

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External class subject 【 display / non-display

  • ,Tohoku University

  • Advances in Dental Anesthesiology,Okayama University