基本情報

写真a

小笠原 暢彦(オガサワラ ノブヒコ)

OGASAWARA Nobuhiko


職名

大学院生

経歴(学内) 【 表示 / 非表示

  • 2020年04月
    -
    現在
    東京医科歯科大学 大学院医歯学総合研究科 医歯学専攻 器官システム制御学講座 消化器病態学分野 大学院生
 

論文・総説 【 表示 / 非表示

  1. Nobuhiko Ogasawara, Yoshihito Kano, Yosuke Yoneyama, Sakurako Kobayashi, Satoshi Watanabe, Sakura Kirino, Fausto D Velez-Bravo, Yourae Hong, Aleksandra Ostapiuk, Pavlo Lutsik, Iichiroh Onishi, Shinichi Yamauchi, Yui Hiraguri, Go Ito, Yusuke Kinugasa, Kenichi Ohashi, Mamoru Watanabe, Ryuichi Okamoto, Sabine Tejpar, Shiro Yui. Discovery of non-genomic drivers of YAP signaling modulating the cell plasticity in CRC tumor lines. iScience. 2024.03; 27 (3): 109247. ( PubMed, DOI )

  2. Satoshi Watanabe, Nobuhiko Ogasawara, Sakurako Kobayashi, Sakura Kirino, Masami Inoue, Yui Hiraguri, Sayaka Nagata, Hiromichi Shimizu, Go Ito, Tomohiro Mizutani, Yasuhiro Nemoto, Kiichiro Tsuchiya, Ryuichi Okamoto, Mamoru Watanabe, Shiro Yui. Organoids transplantation as a new modality to design epithelial signature to create a membrane-protective sulfomucin-enriched segment. J Gastroenterol. 2023.04; 58 (4): 379-393. ( PubMed, DOI )

  3. Sakurako Kobayashi, Nobuhiko Ogasawara, Satoshi Watanabe, Yosuke Yoneyama, Sakura Kirino, Yui Hiraguri, Masami Inoue, Sayaka Nagata, Yoshimi Okamoto-Uchida, Satoshi Kofuji, Hiromichi Shimizu, Go Ito, Tomohiro Mizutani, Shinichi Yamauchi, Yusuke Kinugasa, Yoshihito Kano, Yasuhiro Nemoto, Mamoru Watanabe, Kiichiro Tsuchiya, Hiroshi Nishina, Ryuichi Okamoto, Shiro Yui. Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation. Inflamm Regen. 2022.11; 42 (1): 49. ( PubMed, DOI )

  4. Satoshi Watanabe, Sakurako Kobayashi, Nobuhiko Ogasawara, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe, Kim B Jensen, Shiro Yui. Transplantation of intestinal organoids into a mouse model of colitis. Nat Protoc. 2022.02; ( PubMed, DOI )

講演・口頭発表等 【 表示 / 非表示

  1. Nobuhiko Ogasawara, Yoshihito Kano, Sakurako Kobayashi, Satoshi Watanabe, Sakura Kirino, Iichiroh Onishi, Shinichi Yamauchi, Yui Hiraguri, Go Ito, Mamoru Watanabe, Yusuke Kinugasa, Kenichi Ohashi, Ryuichi Okamoto, Shiro Yui. ECM-niche dependent plasticity controlsthe acquisition of invasive phenotype in colorectal cancer. The 82nd Annual Meeting Of The Japanese Cancer Association 2023.09.21 Yokohama_Japan

  2. Nobuhiko Ogasawara, Yoshihito Kano, Sakurako Kobayashi, Satoshi Watanabe, Sakura Kirino, Shinichi Yamauchi, Yui Hiraguri, Go Ito, Tomohiro Mizutani, Mamoru Watanabe, Yusuke Kinugasa, Ryuichi Okamoto, Shiro Yui. Unveiling the gene network behind cell plasticity provides a novel insight into the therapeutic approach for human colorectal cancer. Keystone Symposia 2023.05.11 Vancouver_Canada

その他業績 【 表示 / 非表示

  • 「 大腸癌の進展に関わる非ゲノム型YAP活性化機構の同定 」 ― 腫瘍微小環境を再定義し、癌を治る病気にする―,2024年03月

    iScience

  • From grave to cradle: Collagen-induced gut cell reprogramming,2023年01月

    AAAS EurekAlert! The Global Source for Science News

  • 「 Ⅰ型コラーゲンを介した腸上皮の炎症・再生機構の解明 」 ― 細胞外基質が細胞運命の転換を司る ―,2022年12月

    Inflammation and Regeneration