Personnel Information

写真a

MUTO Tomohiro


Job title

Project Researcher
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Campus Career 【 display / non-display 】

  • 2021.04
    -
    2024.09
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Systemic Organ Regulation， Department of Gastroenterology and Hepatology， Graduate Student
  • 2024.10
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    2026.07
    Institute of Science Tokyo， -， Graduate Schools， Systemic Organ Regulation， Department of Gastroenterology and Hepatology， Graduate Student
  • 2026.08
    -
    Now
    Institute of Science Tokyo， -， Graduate Schools， Systemic Organ Regulation， Department of Gastroenterology and Hepatology， Project Researcher
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Published Papers & Misc 【 display / non-display 】

  1. Tomohiro Muto, Go Ito, Hiromune Katsuda, Yui Hiraguri, Satoru Fujii, Kurara Yamamoto, Joana P Bernardes, Finn Hinrichsen, Hitoshi Uchida, Yasuhiro Nemoto, Mayumi Kinoshita, Eri Oshina, Kouhei Yamamoto, Shuji Hibiya, Sayaka Nagata, Fenja Schuran, Shiro Yui, Penelope Pelczar, Samuel Huber, Stefan Schreiber, Philip Rosenstiel, Mamoru Watanabe, Ryuichi Okamoto. IL-22 induces Paneth cell metaplasia in the colonic epithelium of ulcerative colitis, promoting wound healing via REG3A. Nat Commun. 2026.03; 17 (1): ( PubMed, DOI )

  2. Hiromune Katsuda, Go Ito, Franziska Kimmig, Tomohiro Muto, Neha Mishra, Joana Pimenta Bernardes, Yui Hiraguri, Hironari Yamashita, Akira Ito, Yuko Kinowaki, Takahiro Shin, Satoru Fujii, Masato Miyoshi, Masanori Kobayashi, Daisuke Asano, Yoshiya Ishikawa, Hiroki Ueda, Keiichi Akahoshi, Eriko Katsuta, Yoshihito Kano, Shiro Yui, Yasuhiro Nemoto, Atsushi Kudo, Daisuke Ban, Yasuhiro Asahina, Stefan Schreiber, Mamoru Watanabe, Philip Rosenstiel, Ryuichi Okamoto. DOCK10 Regulates Insulin Hypersecretion in Insulinoma and Serves as a Diagnostic and Therapeutic Target. Cell Mol Gastroenterol Hepatol. 2026; 20 (5): 101705. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display 】

  1. Tomohiro Muto. Exploring Mechanisms of Epithelial Regeneration in Ulcerative Colitis through Paneth Cell Metaplasia. Japanese Society of Gastroenterology (JSGE)-United European Gastroenterology (UEG) Rising Stars Session, United European Gastroenterology Week (UEG Week) 2026 2026.10.20 Barcelona, Spain

  2. Tomohiro Muto, Go Ito, Hiromune Katsuda, Kurara Yamamoto, [Yui H. 要確認], Joana P. Bernardes, Finn Hinrichsen, Eri Oshina, Shuji Hibiya, Satoru Fujii, Yasuhiro Nemoto, Stefan Schreiber, Philip Rosenstiel, Ryuichi Okamoto. IL-22–Induced Paneth Cell Metaplasia Promotes Epithelial Proliferation and Is Associated with Neoplastic Risk in Ulcerative Colitis. United European Gastroenterology Week (UEG Week) 2026 2026.10.18 Barcelona, Spain

  3. Tomohiro Muto, Go Ito, Hiromune Katsuda, Kurara Yamamoto, Yui Hiraguri, Shuji Hibiya, Satoru Fujii, Yasuhiro Nemoto, Ryuichi Okamoto. Paneth Cell Metaplasia Promotes Mucosal Healing via REG3A-Mediated Epithelial Regeneration in Ulcerative Colitis. AOCC 2026 & IMKASID 2026 (The 14th Annual Meeting of the Asian Organization for Crohn's & Colitis in conjunction with the 9th International Meeting on Intestinal Diseases and Annual Congress of the Korean Association for the Study of Intestinal Diseases) 2026.06.25 Seoul, Korea

  4. Tomohiro Muto,Go Ito,Hiromune Katsuda,Yui Hiraguri,Kurara Yamamoto,Joana P.Bernardes,Finn Hinrichsen,Eri Oshima,Shuji Hibiya,Satoru Fujii,Yasuhiro Nemoto,Philip Rosenstiel,Ryuichi Okamoto. MECHANISTIC INSIGHTS INTO THE NOVEL PROTECTIVE ROLE OF PANETH CELL METAPLASIA IN THE INFLAMED COLONIC EPITHELIUM OF ULCERATIVE COLITIS. DDW2026 2026.05.03 Chicago McCormick Place

  5. 武藤智弘,伊藤剛,勝田景統,山本くらら,平栗優衣,内田仁,藤井悟,日比谷秀爾,根本泰宏,岡本隆一. Characteristics of Paneth Cell Metaplasia in Ulcerative Colitis and Its Mechanisms in Epithelial Wound Healing under Inflammatory Conditions. 第112回日本消化器病学会 2026.04.17 コートヤード・バイ・マリオット福井

  6. Muto Tomohiro, Ito Go, Katsuda Hiromune, Yamamoto Kurara, Hiraguri Yui, Uchida Hitoshi, Fujii Satoru, Hibiya Shuji, Nemoto Yasuhiro, Okamoto Ryuichi. 炎症性腸疾患における病態研究・臨床応用の最前線　潰瘍性大腸炎におけるパネート細胞化生の特徴と炎症環境下での上皮創傷治癒機構の解明(The cutting edge of pathophysiological(basic) research and clinical application in inflammatory bowel disease　Characteristics of Paneth Cell Metaplasia in Ulcerative Colitis and Its Mechanisms in Epithelial Wound Healing under Inflammatory Conditions). 日本消化器病学会雑誌 2026.03.01

  7. Tomohiro Muto, Go Ito, Hiromune Katsuda, Kurara Yamamoto, Yui Hiraguri, Satoru Fujii, Shuji Hibiya, Sayaka Nagata, Yasuhiro Nemoto, Ryuichi Okamoto. Paneth Cell Metaplasia in the Colonic Epithelium of Ulcerative Colitis Promotes Mucosal Healing via REG3A. United European Gastroenterology Week (UEG Week) 2025 2025.10.07 Berlin, Germany

  8. Tomohiro Muto, Go Ito, Hiromune Katsuda, Yui Hiraguri, Satoru Fujii, Kurara Yamamoto, Shuji Hibiya, Sayaka Nagata, Yasuhiro Nemoto, Ryuichi Okamoto. The Protective Role of Paneth Cell Metaplasia in the Colonic Epithelium of Ulcerative Colitis. The 13th Annual Meeting of the Asian Organization for Crohn's & Colitis (AOCC) 2025 2025.07.11 Chiba, Japan

  9. Hiromune Katsuda, Go Ito, Yui Hiraguri, Tomohiro Muto, Shun Ishido, Masanori Kobayashi, Hironari Yamashita, Akira Ito, Hiroaki Ono, Atsushi Kudo, Mamoru Watanabe, Minoru Tanabe, Ryuichi Okamoto. Analysis of gene expression to elucidate the pathogenesis of pancreatic solid pseudopapillary neoplasm.. UEGW2023 2023.10.14 Copenhagen_Denmark

  10. Inada Kento, Nakanishi Hiroyuki, Muto Tomohiro, Kirino Sakura, Yamashita Koji, Osawa Leona, Sekiguchi Shuhei, Hayakawa Yuka, Higuchi Mayu, Takaura Kenta, Maeyashiki Chiaki, Kaneko Shun, Yasui Yutaka, Itakura Jun, Takahashi Yuka, Tsuchiya Kaoru, Kurosaki Masayuki, Izumi Namiki. NBI併用拡大内視鏡検査で発見された早期胃癌の微小粘膜下浸潤の予測における拡張血管の臨床的有用性(Clinical usefulness of dilated vessels in early gastric cancer found by magnifying endoscopy with narrow-band imaging for predicting minute submucosal invasion). 日本消化器病学会雑誌 2021.10.01

  11. Inada Kento, Nakanishi Hiroyuki, Muto Tomohiro, Kirino Sakura, Yamashita Koji, Osawa Leona, Sekiguchi Shuhei, Hayakawa Yuka, Higuchi Mayu, Takaura Kenta, Maeyashiki Chiaki, Kaneko Shun, Yasui Yutaka, Itakura Jun, Takahashi Yuka, Tsuchiya Kaoru, Kurosaki Masayuki, Izumi Namiki. 狭帯域画像を用いた拡大内視鏡検査で発見された早期胃癌の拡張血管の微小粘膜下浸潤予測に関する臨床的有用性(Clinical usefulness of dilated vessels in early gastric cancer found by magnifying endoscopy with narrow-band imaging for predicting minute submucosal invasion). 日本消化器がん検診学会雑誌 2021.10.01

  12. Inada Kento, Nakanishi Hiroyuki, Muto Tomohiro, Kirino Sakura, Yamashita Koji, Osawa Leona, Sekiguchi Shuhei, Hayakawa Yuka, Higuchi Mayu, Takaura Kenta, Maeyashiki Chiaki, Kaneko Shun, Yasui Yutaka, Itakura Jun, Takahashi Yuka, Tsuchiya Kaoru, Kurosaki Masayuki, Izumi Namiki. 微小粘膜下浸潤を予測するための狭帯域光観察による拡大内視鏡検査によって発見された早期胃がんにおける拡張血管の臨床的有用性について(Clinical usefulness of dilated vessels in early gastric cancer found by magnifying endoscopy with narrow-band imaging for predicting minute submucosal invasion). Gastroenterological Endoscopy 2021.10.01

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Awards & Honors 【 display / non-display 】

  • UEG National Scholar 2026，United European Gastroenterology(UEG)，2026.07

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Others 【 display / non-display 】

  • Paneth cell metaplasia may act as a protective response in ulcerative colitis，2026.06

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