論文・総説 - 上阪　直史

21. Yamashiro K, Hori K, Lai ESK, Aoki R, Shimaoka K, Arimura N, Egusa SF, Sakamoto A, Abe M, Sakimura K, Watanabe T, Uesaka N, Kano M, Hoshino M. AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication. iScience. 2020.12; 23 (12): 101820. ( PubMed, DOI )

22. Sacai H, Sakoori K, Konno K, Nagahama K, Suzuki H, Watanabe T, Watanabe M, Uesaka N, Kano M. Autism spectrum disorder-like behavior caused by reduced excitatory synaptic transmission in pyramidal neurons of mouse prefrontal cortex. Nature communications. 2020.10; 11 (1): 5140. ( PubMed, DOI )

23. Nagumo Yasuyuki, Ueta Yoshifumi, Nakayama Hisako, Osaki Hironobu, Takeuchi Yuichi, Uesaka Naofumi, Kano Masanobu, Miyata Mariko. Tonic GABAergic Inhibition Is Essential for Nerve Injury-Induced Afferent Remodeling in the Somatosensory Thalamus and Ectopic Sensations CELL REPORTS. 2020.06; 31 (12): 107797. ( PubMed, DOI )

24. Rai Y, Watanabe T, Matsuyama K, Sakimura K, Uesaka N, Kano M. Phospholipase C β3 is Required for Climbing Fiber Synapse Elimination in Aldolase C-positive Compartments of the Developing Mouse Cerebellum. Neuroscience. 2020.04; ( PubMed, DOI )

25. Watanabe Takaki, Suzuki Honoka, Sakoori Kazuto, Inoue Shutaro, Akamatsu Tsubasa, Abe Manabu, Sakimura Kenji, Uesaka Naofumi, Kano Masanobu. Protocadherin 10 delays developmental climbing fiber synapse elimination in a subset of aldolase C-positive Purkinje cells in the cerebellum(和訳中) The Journal of Physiological Sciences. 2020.03; 70 (Suppl.1): S97. ( 医中誌 )

26. Saito R, Koebis M, Nagai T, Shimizu K, Liao J, Wulaer B, Sugaya Y, Nagahama K, Uesaka N, Kushima I, Mori D, Maruyama K, Nakao K, Kurihara H, Yamada K, Kano M, Fukada Y, Ozaki N, Aiba A. Comprehensive analysis of a novel mouse model of the 22q11.2 deletion syndrome: a model with the most common 3.0-Mb deletion at the human 22q11.2 locus. Translational psychiatry. 2020.02; 10 (1): 35. ( PubMed, DOI )

27. Kushibe Kyoko, Mercier Celine, Watanabe Takaki, Miyazaki Taisuke, Yamasaki Miwako, Watanabe Masahiko, Uesaka Naofumi, Kano Masanobu. Fndc3bは小脳のSTAT3を阻害することにより登上線維のシナプス刈り込みを部分的に促進する(Fndc3b promotes climbing fiber synapse elimination partly by inhibiting STAT3 in the cerebellum) The Journal of Physiological Sciences. 2019.06; 69 (Suppl.1): S127. ( 医中誌 )

28. Watanabe Takaki, Inoue Shutaro, Akamatsu Tsubasa, Suzuki Honoka, Abe Manabu, Sakimura Kenji, Uesaka Naofumi, Kano Masanobu. Protocadherin 10を欠く小脳プルキンエ細胞における登上線維のシナプス刈り込みの促進(Accelerated climbing fiber synapse elimination in cerebellar Purkinje cells lacking protocadherin 10) The Journal of Physiological Sciences. 2019.06; 69 (Suppl.1): S221. ( 医中誌 )

29. Nagahama Kenichiro, Sakoori Kazuto, Watanabe Takaki, Uesaka Naofumi, Kano Masanobu. 精神障害関連エピジェネティック因子の欠如による前頭前野でのシナプス入力の減少(Reduced synaptic inputs in prefrontal cortex by lack of a mental disorder-related epigenetic factor) The Journal of Physiological Sciences. 2019.06; 69 (Suppl.1): S143. ( 医中誌 )

30. Uesaka Naofumi, Kao Tzu-Huei, Kano Masanobu. 健康および疾患におけるシナプスのリモデリングとその先　小脳発生における活動依存性シナプス刈り込み(Synaptic remodeling and beyond in health and disease　Activity-dependent synapse elimination in the developing cerebellum) The Journal of Physiological Sciences. 2019.06; 69 (Suppl.1): S35. ( 医中誌 )

31. Kano M, Watanabe T, Uesaka N, Watanabe M. Multiple Phases of Climbing Fiber Synapse Elimination in the Developing Cerebellum. Cerebellum (London, England). 2018.12; 17 (6): 722-734. ( PubMed, DOI )

32. Nagahama Kenichiro, Sakoori Kazuto, Watanabe Takaki, Uesaka Naofumi, Kano Masanobu. 生後発達期のマウス内側前頭前野のニューロンにおいて統合失調症関連分子Setd1aをノックダウンした場合のシナプス伝達の減弱(Reduced synaptic transmission in neurons of mouse medial prefrontal cortex by knockdown of a schizophrenia-related molecule, Setd1a, during postnatal development) The Journal of Physiological Sciences. 2018.03; 68 (Suppl.1): S131. ( 医中誌 )

33. Uesaka N, Kano M. Presynaptic Mechanisms Mediating Retrograde Semaphorin Signals for Climbing Fiber Synapse Elimination During Postnatal Cerebellar Development. Cerebellum (London, England). 2018.02; 17 (1): 17-22. ( PubMed, DOI )

34. Uesaka N, Abe M, Konno K, Yamazaki M, Sakoori K, Watanabe T, Kao TH, Mikuni T, Watanabe M, Sakimura K, Kano M. Retrograde Signaling from Progranulin to Sort1 Counteracts Synapse Elimination in the Developing Cerebellum. Neuron. 2018.02; 97 (4): 796-805.e5. ( PubMed, DOI )

35. Choo M, Miyazaki T, Yamazaki M, Kawamura M, Nakazawa T, Zhang J, Tanimura A, Uesaka N, Watanabe M, Sakimura K, Kano M. Retrograde BDNF to TrkB signaling promotes synapse elimination in the developing cerebellum. Nature communications. 2017.08; 8 (1): 195. ( PubMed, DOI )

36. Leto Ketty, Arancillo Marife, Becker Esther B. E., Buffo Annalisa, Chiang Chin, Ding Baojin, Dobyns William B., Dusart Isabelle, Haldipur Parthiv, Hatten Mary E., Hoshino Mikio, Joyner Alexandra L., Kano Masanobu, Kilpatrick Daniel L., Koibuchi Noriyuki, Marino Silvia, Martinez Salvador, Millen Kathleen J., Millner Thomas O., Miyata Takaki, Parmigiani Elena, Schilling Karl, Sekerkova Gabriella, Sillitoe Roy V., Sotelo Constantino, Uesaka Naofumi, Wefers Annika, Wingate Richard J. T., Hawkes Richard. Consensus Paper: Cerebellar Development CEREBELLUM. 2016.12; 15 (6): 789-828. ( DOI )

37. Narushima Madoka, Uchigashima Motokazu, Yagasaki Yuki, Harada Takeshi, Nagumo Yasuyuki, Uesaka Naofumi, Hashimoto Kouichi, Aiba Atsu, Watanabe Masahiko, Miyata Mariko, Kano Masanobu. The Metabotropic Glutamate Receptor Subtype 1 Mediates Experience-Dependent Maintenance of Mature Synaptic Connectivity in the Visual Thalamus NEURON. 2016.09; 91 (5): 1097-1109. ( DOI )

38. Uesaka Naofumi, Uchigashima Motokazu, Mikuni Takayasu, Hirai Hirokazu, Watanabe Masahiko, Kano Masanobu. Retrograde Signaling for Climbing Fiber Synapse Elimination CEREBELLUM. 2015.02; 14 (1): 4-7. ( DOI )

39. Uesaka Naofumi, Uchigashima Motokazu, Mikuni Takayasu, Nakazawa Takanobu, Nakao Harumi, Hirai Hirokazu, Aiba Atsu, Watanabe Masahiko, Kano Masanobu. Retrograde semaphorin signaling regulates synapse elimination in the developing mouse brain SCIENCE. 2014.05; 344 (6187): 1020-1023. ( DOI )

40. Mikuni Takayasu, Uesaka Naofumi, Okuno Hiroyuki, Hirai Hirokazu, Deisseroth Karl, Bito Haruhiko, Kano Masanobu. Arc/Arg3.1 Is a Postsynaptic Mediator of Activity-Dependent Synapse Elimination in the Developing Cerebellum NEURON. 2013.06; 78 (6): 1024-1035. ( DOI )