Published Papers & Misc - TAZAWA Ryushi

21. Masayuki Ito, Kazuyuki Nakagome, Hiromitsu Ohta, Keiichi Akasaka, Yoshitaka Uchida, Atsushi Hashimoto, Ayako Shiono, Toshinori Takada, Makoto Nagata, Jun Tohyama, Koichi Hagiwara, Minoru Kanazawa, Koh Nakata, Ryushi Tazawa. Elderly-onset hereditary pulmonary alveolar proteinosis and its cytokine profile. BMC Pulm Med. 2017.02; 17 (1): 40. ( PubMed, DOI )

22. Toshinori Takada, Ayako Mikami, Nobutaka Kitamura, Kuniaki Seyama, Yoshikazu Inoue, Katsura Nagai, Masaru Suzuki, Hiroshi Moriyama, Keiichi Akasaka, Ryushi Tazawa, Toyohiro Hirai, Michiaki Mishima, Mie Hayashida, Masaki Hirose, Chikatoshi Sugimoto, Toru Arai, Noboru Hattori, Kentaro Watanabe, Tsutomu Tamada, Hirohisa Yoshizawa, Kohei Akazawa, Takahiro Tanaka, Keita Yagi, Lisa R Young, Francis X McCormack, Koh Nakata. Efficacy and Safety of Long-Term Sirolimus Therapy for Asian Patients with Lymphangioleiomyomatosis. Ann Am Thorac Soc. 2016.11; 13 (11): 1912-1922. ( PubMed, DOI )

23. Tazawa Ryushi, Nakata Koh. Pulmonary alveolar proteinosis and granulocyte/macrophage-colony stimulating factor (GM-CSF) inhalation Exp. Opin. Orphan Drugs. 2016.01; 4 (1): 115-123. ( DOI )

24. Keiichi Akasaka, Takahiro Tanaka, Nobutaka Kitamura, Shinya Ohkouchi, Ryushi Tazawa, Toshinori Takada, Toshio Ichiwata, Etsuro Yamaguchi, Masaki Hirose, Toru Arai, Kentaro Nakano, Takahito Nei, Haruyuki Ishii, Tomohiro Handa, Yoshikazu Inoue, Koh Nakata. Outcome of corticosteroid administration in autoimmune pulmonary alveolar proteinosis: a retrospective cohort study. BMC Pulm Med. 2015.08; 15 88. ( PubMed, DOI )

25. Masato Moriyama, Toshio Yano, Tatsuo Furukawa, Toshinori Takada, Takashi Ushiki, Masayoshi Masuko, Jun Takizawa, Hirohito Sone, Ryushi Tazawa, Yasuo Saijo, Haruyuki Ishii, Koh Nakata. Possible Involvement of Lung Cells Harboring an Abnormal Karyotype in the Pathogenesis of Pulmonary Alveolar Proteinosis Associated with Myelodysplastic Syndrome. Ann Am Thorac Soc. 2015.08; 12 (8): 1251-1253. ( PubMed, DOI )

26. Keiichi Akasaka, Takahiro Tanaka, Takashi Maruyama, Nobutaka Kitamura, Atsushi Hashimoto, Yuko Ito, Hiroyoshi Watanabe, Tomoshige Wakayama, Takero Arai, Masachika Hayashi, Hiroshi Moriyama, Kanji Uchida, Shinya Ohkouchi, Ryushi Tazawa, Toshinori Takada, Etsuro Yamaguchi, Toshio Ichiwata, Masaki Hirose, Toru Arai, Yoshikazu Inoue, Hirosuke Kobayashi, Koh Nakata. A mathematical model to predict protein wash out kinetics during whole-lung lavage in autoimmune pulmonary alveolar proteinosis. Am. J. Physiol. Lung Cell Mol. Physiol.. 2015.01; 308 (2): L105-L117. ( PubMed, DOI )

27. Takehiro Serikawa, Kenichi Nishiyama, Jun Tohyama, Ryushi Tazawa, Kiyoe Goto, Yoko Kuriyama, Kazufumi Haino, Yonehiro Kanemura, Mami Yamasaki, Koh Nakata, Koichi Takakuwa, Takayuki Enomoto. Prenatal molecular diagnosis of X-linked hydrocephalus via a silent C924T mutation in the L1CAM gene. Congenit Anom (Kyoto). 2014.11; 54 (4): 243-245. ( PubMed, DOI )

28. Atsushi Hashimoto, Takahiro Tanaka, Yuko Itoh, Akira Yamagata, Nobutaka Kitamura, Ryushi Tazawa, Kazuhide Nakagaki, Koh Nakata. Low concentrations of recombinant granulocyte macrophage-colony stimulating factor derived from Chinese hamster ovary cells augments long-term bioactivity with delayed clearance in vitro. Cytokine. 2014.08; 68 (2): 118-126. ( PubMed, DOI )

29. Kazuhide Nakagaki, Yuka Nunomura, Kanji Uchida, Koh Nakata, Ryushi Tazawa. Up-regulation of cluster of differentiation (CD) 11b expression on the surface of canine granulocytes with human granulocyte-macrophage colony-stimulating factor (GM-CSF). J. Vet. Med. Sci.. 2014.08; 76 (8): 1173-1176. ( PubMed, DOI )

30. Ryushi Tazawa, Yoshikazu Inoue, Toru Arai, Toshinori Takada, Yasunori Kasahara, Masayuki Hojo, Shinya Ohkouchi, Yoshiko Tsuchihashi, Masanori Yokoba, Ryosuke Eda, Hideaki Nakayama, Haruyuki Ishii, Takahito Nei, Konosuke Morimoto, Yasuyuki Nasuhara, Masahito Ebina, Masanori Akira, Toshio Ichiwata, Koichiro Tatsumi, Etsuro Yamaguchi, Koh Nakata. Duration of benefit in patients with autoimmune pulmonary alveolar proteinosis after inhaled granulocyte-macrophage colony-stimulating factor therapy. Chest. 2014.04; 145 (4): 729-737. ( PubMed, DOI )

31. Haruyuki Ishii, John F Seymour, Ryushi Tazawa, Yoshikazu Inoue, Naoyuki Uchida, Aya Nishida, Yoshihito Kogure, Takeshi Saraya, Keisuke Tomii, Toshinori Takada, Yuko Itoh, Masayuki Hojo, Toshio Ichiwata, Hajime Goto, Koh Nakata. Secondary pulmonary alveolar proteinosis complicating myelodysplastic syndrome results in worsening of prognosis: a retrospective cohort study in Japan. BMC Pulm Med. 2014.03; 14 37. ( PubMed, DOI )

32. Takahito Nei, Shinya Urano, Yuko Itoh, Nobutaka Kitamura, Atsushi Hashimoto, Takahiro Tanaka, Natsuki Motoi, Chinatsu Kaneko, Ryushi Tazawa, Kazuhide Nakagaki, Toru Arai, Yoshikazu Inoue, Koh Nakata. Light chain (κ/λ) ratio of GM-CSF autoantibodies is associated with disease severity in autoimmune pulmonary alveolar proteinosis. Clin. Immunol.. 2013.12; 149 (3): 357-364. ( PubMed, DOI )

33. Shu Hisata, Hiroshi Moriyama, Ryushi Tazawa, Shinya Ohkouchi, Masakazu Ichinose, Masahito Ebina. Development of pulmonary alveolar proteinosis following exposure to dust after the Great East Japan Earthquake. Respir Investig. 2013.12; 51 (4): 212-216. ( PubMed, DOI )

34. Hiroki Maruyama, Takuma Takata, Yutaka Tsubata, Ryushi Tazawa, Kiyoe Goto, Jun Tohyama, Ichiei Narita, Hidekatsu Yoshioka, Satoshi Ishii. Screening of male dialysis patients for fabry disease by plasma globotriaosylsphingosine. Clin J Am Soc Nephrol. 2013.04; 8 (4): 629-636. ( PubMed, DOI )

35. Won Fen Wong, Kazuyoshi Kohu, Akira Nakamura, Masahito Ebina, Toshiaki Kikuchi, Ryushi Tazawa, Keisuke Tanaka, Shunsuke Kon, Tomo Funaki, Akiko Sugahara-Tobinai, Chung Yeng Looi, Shota Endo, Ryo Funayama, Mineo Kurokawa, Sonoko Habu, Naoto Ishii, Manabu Fukumoto, Koh Nakata, Toshiyuki Takai, Masanobu Satake. Runx1 deficiency in CD4+ T cells causes fatal autoimmune inflammatory lung disease due to spontaneous hyperactivation of cells. J. Immunol.. 2012.06; 188 (11): 5408-5420. ( PubMed, DOI )

36. Takahito Nei, Shinya Urano, Natsuki Motoi, Jun Takizawa, Chinatsu Kaneko, Hiroko Kanazawa, Ryushi Tazawa, Kazuhide Nakagaki, Kiyoko S Akagawa, Keiichi Akasaka, Toshio Ichiwata, Arata Azuma, Koh Nakata. IgM-type GM-CSF autoantibody is etiologically a bystander but associated with IgG-type autoantibody production in autoimmune pulmonary alveolar proteinosis. Am. J. Physiol. Lung Cell Mol. Physiol.. 2012.05; 302 (9): L959-L964. ( PubMed, DOI )

37. K Ohashi, A Sato, T Takada, T Arai, Y Kasahara, M Hojo, T Nei, H Nakayama, N Motoi, S Urano, R Eda, M Yokoba, Y Tsuchihashi, Y Nasuhara, H Ishii, M Ebina, E Yamaguchi, Y Inoue, K Nakata, R Tazawa. Reduced GM-CSF autoantibody in improved lung of autoimmune pulmonary alveolar proteinosis. Eur. Respir. J.. 2012.03; 39 (3): 777-780. ( PubMed, DOI )

38. Kazumasa Ohashi, Atsuyasu Sato, Toshinori Takada, Toru Arai, Takahito Nei, Yasunori Kasahara, Natsuki Motoi, Masayuki Hojo, Shinya Urano, Haruyuki Ishii, Masanori Yokoba, Ryosuke Eda, Hideaki Nakayama, Yasuyuki Nasuhara, Yoshiko Tsuchihashi, Chinatsu Kaneko, Hiroko Kanazawa, Masahito Ebina, Etsuro Yamaguchi, Jacqueline Kirchner, Yoshikazu Inoue, Koh Nakata, Ryushi Tazawa. Direct evidence that GM-CSF inhalation improves lung clearance in pulmonary alveolar proteinosis. Respir Med. 2012.02; 106 (2): 284-293. ( PubMed, DOI )

39. Hironori Satoh, Ryushi Tazawa, Tomohiro Sakakibara, Shinya Ohkouchi, Masahito Ebina, Makoto Miki, Koh Nakata, Toshihiro Nukiwa. Bilateral peripheral infiltrates refractory to immunosuppressants were diagnosed as autoimmune pulmonary alveolar proteinosis and improved by inhalation of granulocyte/macrophage-colony stimulating factor. Intern. Med.. 2012; 51 (13): 1737-1742. ( PubMed, DOI )

40. Shinya Urano, Ryushi Tazawa, Takahito Nei, Natsuki Motoi, Masato Watanabe, Takenori Igarashi, Masahiro Tomita, Koh Nakata. A cell free assay system estimating the neutralizing capacity of GM-CSF antibody using recombinant soluble GM-CSF receptor. J Vis Exp. 2011.06; (52): ( PubMed, DOI )