Personnel Information

写真a

SHIMOHIRA Tsuyoshi
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Campus Career 【 display / non-display 】

  • 2018.04
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Bio-Matrix， Periodontology， Graduate Student
  • 2019.04
    -
    2023.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Bio-Matrix， Department of Periodontology， Graduate Student
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Published Papers & Misc 【 display / non-display 】

  1. Lin P, Niimi H, Hirota T, Ohsugi Y, Shimohira T, Toyoshima K, Katagiri S, Iwata T, Aoki A. Effects of low-level Er:YAG laser irradiation on proliferation and gene expression in primary gingival fibroblasts isolated from mouse maxilla J Biophotonics. 2023.11; e202300166. ( PubMed, DOI )

  2. Ohsugi Y, Hatasa M, Katagiri S, Hirota T, Shimohira T, Shiba T, Komatsu K, Tsuchiya Y, Fukuba S, Lin P, Toyoshima K, Maekawa S, Niimi H, Iwata T, Aoki A. High-frequency pulsed diode laser irradiation inhibits bone resorption in mice with ligature-induced periodontitis Journal of Clinical Periodontology. 2022.07; e-pub ( PubMed, DOI )

  3. Yoshida S, Hatasa M, Ohsugi Y, Tsuchiya Y, Liu A, Niimi H, Morita K, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Okano T, Hirose A, Ibi R, Noritake K, Tomiga Y, Nitta H, Suzuki T, Takahashi H, Miyasaka N, Iwata T, Katagiri S. Porphyromonas gingivalis administration induces gestational obesity, alters gene expression in the liver and brown adipose tissue in pregnant mice, and causes underweight in fetuses Frontiers in Cellular and Infection Microbiology. 2022.01; 11 745117. ( PubMed, DOI )

  4. Shimohira T, Niimi H, Ohsugi Y, Tsuchiya Y, Morita K, Yoshida S, Hatasa M, Shiba T, Kadokura H, Yokose S, Katagiri S, Iwata T, Aoki A. Low-level erbium-doped yttrium aluminum garnet laser irradiation induced alteration of gene expression in osteogenic cells from rat calvariae Photobiomodulation, Photobiomedicine, and Laser Surgery. 2021.08; 39 (8): 566-577. ( DOI )

  5. Lin P, Niimi H, Ohsugi Y, Tsuchiya Y, Shimohira T, Komatsu K, Liu A, Shiba T, Aoki A, Iwata T, Katagiri S. Application of Ligature-Induced Periodontitis in Mice to Explore the Molecular Mechanism of Periodontal Disease International Journal of Molecular Sciences. 2021.08; 22 (16): 8900. ( PubMed, DOI )

  6. 大杉 勇人, 新見 ひろみ, 下平 剛, 片桐さやか, 岩田 隆紀, 青木 章. 特集 レーザー再起動! 6. ErYAGレーザーの骨組織への効果のエビデンス 日本歯科評論. 2021.04; 81 (4): 68-71.

  7. Shimohira T, Katagiri S, Ohsugi Y, Hirota T, Hatasa M, Mizutani K, Watanabe K, Niimi H, Iwata T, Aoki A. Comprehensive and Sequential Gene Expression Analysis of Bone Healing Process Following Er:YAG Laser Ablation Photobiomodulation, Photobiomedicine, and Laser Surgery. 2021.02; 39 (2): 100-112. ( PubMed, DOI )

  8. Hatasa M, Ohsugi Y, Katagiri S, Yoshida S, Niimi H, Morita K, Tsuchiya Y, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Tohara H, Takahashi H, Nitta H, Iwata T. Endotoxemia by Porphyromonas gingivalis alters endocrine functions in brown adipose tissue Frontiers in Cellular and Infection Microbiology. 2021.01; 19 (10): 580577.

  9. Ohsugi Y, Niimi H, Shimohira T, Hatasa M, Katagiri S, Aoki A, Iwata T. In vitro cytological responses against laser photobiomodulation for periodontal regeneration International Journal of Molecular Sciences. 2020.11; 21 (23):

  10. Ohsugi Y, Katagiri S, Hirota T, Niimi N, Hatasa M, Watanabe K, Shimohira T, Mizutani K, Kitazawa M, Matsuzawa A, Kadokura H, Yokose S, Iwata T, Aoki A. Laser irradiation decreases sclerostin expression in bone and osteogenic cells. The FASEB Journal. 2020.08; 34 (9): 12877-12893.

  11. Niimi H, Ohsugi Y, Katagiri S, Watanabe K, Hatasa M, Shimohira T, Tsuchiya Y, Maekawa S, Hirota T, Kadokura H, Yokose S, Iwata T, Aoki A. Effects of Low-Level Er:YAG Laser Irradiation on Proliferation and Calcification of Primary Osteoblast-Like Cells Isolated From Rat Calvaria Frontiers in cell and developmental biology. 2020.06; 6 (459):

  12. Hatasa M, Ohsugi Y, Katagiri S, Yoshida S, Niimi H, Morita K, Tsuchiya Y, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Tohara H, Takahashi H, Nitta H, Iwata T.. Endotoxemia by Porphyromonas gingivalis alters endocrine functions in brown adipose tissue Frontiers in Cellular and Infection Microbiology. 2020; 10 580577. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display 】

  1. Lin P, Niimi H, Hirota T, Ohsugi Y, Shimohira T, Toyoshima K, Katagiri K, Iwata T, Aoki A. Effect of low-level Er:YAG laser irradiation on proliferation and gene expression changes of primary gingival fibroblasts isolated from mouse maxilla. The 17th Congress of WFLD, Faculty of Pharmacy 2023.04.16 Wrocław Medical University, Wroclaw

  2. Ohsugi Y, Katagiri S, Niimi H, Hatasa M, Watanabe K, Shimohira T, Mizutani K, Kadokura H, Yokose S, Iwata T, Aoki A. Sequential microarray analysis of Er:YAG laser ablated bone tissue. The 99th General Session of the IADR 2021.07.21 Virtual

  3. Shimohira T, Niimi H, Ohsugi Y, Tsuchiya Y, Morita K, Yoshida S, Hatasa M, Shiba T, Kadokura H, Yokose S, Katagiri S, Iwata T, Aoki A. . Low-level Er:YAG laser irradiation induced alteration of gene expression in rat calvarial osteogenic cells. Dental Laser Virtual Scientific Conference 2021 2021.07.16

  4. Er:YAGレーザーによるラット頭蓋骨由来初代培養骨芽細胞様細胞の増殖と石灰化に対する効果. 第32回日本レーザー歯学会総会・学術大会 2020.11.28 誌上開催

  5. Niimi H, Ohsugi Y, Katagiri S, Watanabe K, Hatasa M, Shimohira T, Tsuchiya Y, Maekawa S, Hirota T, Kadokura H, Yokose S, Iwata T, Aoki A. The effects of Er:YAG laser irradiation on primary osteoblast-like cells. AAP 106th Annual Meeting 2020.11.06 Virtual

  6. Hatasa M, Ohsugi Y, Katagiri S, Hirota T, Yoshida S, Morita K, Niimi H, Shimohira T, Watanabe K, Sasaki N, Maekawa S, Nitta H, Iwata T. Endotoxemia by Porphyromonas gingivalis aggravates inflammation in brown adipose tissue. AAP 106th Annual Meeting 2020.11.06

  7. Ohsugi Y, Katagiri S, Hirota T, Niimi H, Hatasa M, Watanabe K, Shimohira T, Mizutani K, Kitazawa M, Matsuzawa A, Kadokura H, Yokose S, Iwata T, Aoki A. Laser irradiation decreases Sost expression in bone and osteogenic cells. The 106th Annual meeting American Academy of Periodontology 2020.11 Web開催

  8. Shimohira T, Katagiri S, Ohsugi Y, Hirota T, Hatasa M, Mizutani K, Watanabe K, Niimi H, Iwata T, Aoki A. Comprehensive and sequential gene expression analysis during bone healing process following Er:YAG laser ablation. The 63rd Spring Meeting of the Japanese Society of Periodontology 2020.07.13

  9. Shimohira T, Katagiri S, Ohsugi Y, Hirota T, Mizutani K, Watanabe K, Niimi H, Hatasa M, Meinzer W, Iwata T, Aoki A . Comprehensive and Sequential Gene expression analysis of bone healing process following Er:YAG laser ablation. World Federation of Laser Dentistry Dubai Congress 2020 2020.02.05 Dubai

  10. Ohsugi Y, Katagiri S, Mizutani K, Takagi T, Kakizaki S, Kitanaka Y, Watanabe K, Niimi H, Hatasa M, Shimohira T, Meinzer W, Hirota T, Iwata T, Aoki A. Microarray analysis of comprehensive gene expression in rat calvarial bone after Er:YAG laser ablation. The first asian pacific division of the World Federation for Laser Dentistry 2019.11.10 Grand Hyatt Beijing, Beijing, Chaina

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Awards & Honors 【 display / non-display 】

  • First Best Poster (Tsuyoshi Shimohira)，World Federation for Laser Dentistry Dubai Congress 2020，2020.02

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