Personnel Information

写真a

UCHIDA Yutaro


Job title

Assistant Professor
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Graduating School 【 display / non-display 】

  • Tokyo Medical and Dental University, Faculty of Medicine, 2023.03, Graduated

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Graduate School 【 display / non-display 】

  • Tokyo Medical and Dental University, Doctor's Course, 2021.03, Completed

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Campus Career 【 display / non-display 】

  • 2018.04
    -
    2021.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Advanced Therapeutic Sciences， Department of Systems BioMedicine， Graduate Student
  • 2023.04
    -
    2024.09
    Tokyo Medical and Dental University， Tokyo Medical and Dental University， Division of Clinical Management， Professional Development Center， Trainee Resident
  • 2024.10
    -
    2025.03
    Institute of Science Tokyo， -， Institute of Science Tokyo Hospital， Division of Clinical Management， Professional Development Center， Trainee Resident
  • 2025.04
    -
    Now
    Institute of Science Tokyo， -， Graduate Schools， Advanced Therapeutic Sciences， Department of Systems BioMedicine， Assistant Professor
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Research Areas 【 display / non-display 】

  • Experimental pathology

  • Genome biology

  • Molecular biology

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Qualification Acquired 【 display / non-display 】

  • Doctor

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Published Papers & Misc 【 display / non-display 】

  1. Junya Ito, Kensuke Miyake, Tomoki Chiba, Kazufusa Takahashi, Yutaro Uchida, Perry J Blackshear, Hiroshi Asahara, Hajime Karasuyama. Tristetraprolin-mediated mRNA destabilization regulates basophil inflammatory responses. Allergol Int. 2025.04; 74 (2): 263-273. ( PubMed, DOI )

  2. Suzu Chida, Tomoki Chiba, Yutaro Uchida, Takahide Matsushima, Ryota Kurimoto, Takayuki Miyazaki, Lisa Yagasaki, Satoshi Nakamura, Emiko Mihara, Junichi Takagi, Keiji Moriyama, Hiroshi Asahara. Impact of mechanotransduction on gene expression changes in periodontal ligament during orthodontic tooth movement. J Bone Miner Metab. 2025.02; ( PubMed, DOI )

  3. Yutaro Uchida, Ryota Kurimoto, Tomoki Chiba, Takahide Matsushima, Goshi Oda, Iichiroh Onishi, Yasuto Takeuchi, Noriko Gotoh, Hiroshi Asahara. RNA binding protein ZCCHC24 promotes tumorigenicity in triple-negative breast cancer. EMBO Rep. 2024.12; 25 (12): 5352-5382. ( PubMed, DOI )

  4. Mengjiao Li, Tatsunori Nishimura, Yasuto Takeuchi, Tsunaki Hongu, Yuming Wang, Daisuke Shiokawa, Kang Wang, Haruka Hirose, Asako Sasahara, Masao Yano, Satoko Ishikawa, Masafumi Inokuchi, Tetsuo Ota, Masahiko Tanabe, Kei-Ichiro Tada, Tetsu Akiyama, Xi Cheng, Chia-Chi Liu, Toshinari Yamashita, Sumio Sugano, Yutaro Uchida, Tomoki Chiba, Hiroshi Asahara, Masahiro Nakagawa, Shinya Sato, Yohei Miyagi, Teppei Shimamura, Luis Augusto E Nagai, Akinori Kanai, Manami Katoh, Seitaro Nomura, Ryuichiro Nakato, Yutaka Suzuki, Arinobu Tojo, Dominic C Voon, Seishi Ogawa, Koji Okamoto, Theodoros Foukakis, Noriko Gotoh. FXYD3 functionally demarcates an ancestral breast cancer stem cell subpopulation with features of drug-tolerant persisters. J Clin Invest. 2023.11; 133 (22): ( PubMed, DOI )

  5. Hiroto Yamamoto, Yutaro Uchida, Ryota Kurimoto, Tomoki Chiba, Takahide Matsushima, Yoshiaki Ito, Maiko Inotsume, Kohei Miyata, Kenta Watanabe, Masaki Inada, Naoki Goshima, Tokujiro Uchida, Hiroshi Asahara. RNA-binding protein LIN28A upregulates transcription factor HIF1α by posttranscriptional regulation via direct binding to UGAU motifs. J Biol Chem. 2023.01; 299 (1): 102791. ( PubMed, DOI )

  6. Yutaro Uchida, Takahide Matsushima, Ryota Kurimoto, Tomoki Chiba, Yuki Inutani, Hiroshi Asahara. Identification of chemical compounds regulating PD-L1 by introducing HiBiT-tagged cells. FEBS Lett. 2021.03; 595 (5): 563-576. ( PubMed, DOI )

  7. Yamamoto H, Uchida Y, Chiba T, Kurimoto R, Matsushima T, Inotsume M, Ishikawa C, Li H, Shiga T, Muratani M, Uchida T, Asahara H. Transcriptome analysis of sevoflurane exposure effects at the different brain regions. PloS one. 2020; 15 (12): e0236771. ( PubMed, DOI )

  8. Uchida Y, Chiba T, Kurimoto R, Asahara H. Post-transcriptional regulation of inflammation by RNA-binding proteins via cis-elements of mRNAs. Journal of biochemistry. 2019.11; 166 (5): 375-382. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display 】

  1. Masayuki Takeda, Reiji Hirai, Nao Watanabe, Yutaro Uchida, Tomoki Chiba, Takahide Matsushima, Hiroshi Asahara. 変形性膝関節症における化学修飾microRNA-140の治療効果. 第37回 日本軟骨代謝学会 2025.03.07

  2. Y. Uchida, R. Kurimoto, T. Chiba, T. Matsushima, G. Oda, I. Onishi, Y. Takeuchi, N. Gotoh, H. Asahara.. RNA Binding Protein ZCCHC24 Maintains Cancer Stem Like Status In Triple Negative Breast Cancer. Cell Bio 2024 2024.12.16

  3. Reiji Hirai, Maho Hashimoto, Masayuki Takeda, Yutaro Uchida, Tomoki Chiba, Hiroshi Asahara. 変形性関節症における化学修飾microRNA-140の治療効果. RNAフロンティアミーティング2024 2024.10.29

  4. 栗本 遼太, 猪爪 舞子, 宮本 和佳, 錦織 杏樹, 千葉 朋希, 松島 隆英, 内田 雄太郎, 淺原 弘嗣. RNA修飾酵素による肺がんの転移制御機構(Regulation of lung cancer metastatic by the RNA-modifying enzyme). 日本癌学会総会記事 2023.09.01

  5. Ryota Kurimoto、Waka Miyamoto、Maiko Inotsume、Reiji Hirai、Tomoki Chiba、Takahide Matsushima、Yutaro Uchida、Yuta Fujii、Yuki Naito、Yuichi Shichino、Mari Mito、Shintaro Iwasaki、Hiroshi Asahara. Regulation of lung cancer metastasis by the RNA-modifying enzyme. 第24回日本RNA学会年会 2023.07.05

  6. Yutaro Uchida、Ryota Kurimoto、Tomoki Chiba、Yasuto Takeuchi、Noriko Gotoh、Hiroshi Asahara. Post-transcriptional regulation of breast cancer stemness by the novel RNA binding protein. RNA2023 2023.05.31

  7. Yutaro Uchida, Ryota Kurimoto, Tomoki Chiba, Yasuto Takeuchi, Noriko Gotoh, Hiroshi Asahara. Post-transcriptional regulation of breast cancer stemness by the novel RNA binding protein. 第23回日本RNA学会年会 2022.07.21

  8. Ryota Kurimoto, Waka Miyamoto, Maiko Inotsume, Tomoki Chiba, TakahideMatsushima, YutaroUchida, Yuta Fujii, Hiroshi Asahara.. Regulation of lung cancer metastasis by the RNA-modifying enzyme. 2022.07.21

  9. Yutaro Uchida, Takahide Matsushima, Ryota Kurimoto, Tomoki Chiba, Yuki lnutani, Hiroshi Asahara.. HiBiT tagging system for high throughput chemical screening for chemotherapy. AACR 2021 2021.04.11

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Awards & Honors 【 display / non-display 】

  • RNA Society Best poster presentation award，RNA Society，2023.06

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