経歴(学内) 【 表示 / 非表示 】
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2018年01月-2018年04月東京医科歯科大学 役職員 特任教授
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2018年05月-2020年03月東京医科歯科大学 特任教授
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2020年04月-現在東京医科歯科大学 大学院医歯学総合研究科 医歯学系専攻 器官システム制御学講座 統合呼吸器病学 特任教授
競争的資金等の研究課題 【 表示 / 非表示 】
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網羅的エクソーム解析を利用した稀少肺疾患の責任遺伝子同定に向けて
文部科学省/日本学術振興会 : 2016年 - 2018年
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肺線維症責任遺伝子同定と疾患由来iPS細胞分化肺細胞による細胞死と線維化の関連性
文部科学省/日本学術振興会
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アスパラギン残基の脱アミド化反応による慢性閉塞性肺疾患発症のメカニズムの解明
文部科学省/日本学術振興会
論文・総説 【 表示 / 非表示 】
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Hosokawa, M; Mikawa, R; Hagiwara, A; Okuno, Y; Awaya, T; Yamamoto, Y; Takahashi, S; Yamaki, H; Osawa, M; Setoguchi, Y; Saito, MK; Abe, S; Hirai, T; Gotoh, S; Hagiwara, M. Cryptotanshinone is a candidate therapeutic agent for interstitial lung disease associated with a BRICHOS-domain mutation of SFTPC ISCIENCE. 2023.10; 26 (10): ( PubMed, DOI )
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Katayanagi S, Setoguchi Y, Kitagawa S, Okamoto T, Miyazaki Y. Alternative gene expression by TOLLIP variant is associated with lung function in chronic hypersensitivity pneumonitis. Chest. 2021.08; ( PubMed, DOI )
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Kawagoe Junichiro, Kono Yuta, Togashi Yuki, Ishiwari Mayuko, Toriyama Kazutoshi, Yajima Chika, Nakayama Hideaki, Kasagi Satoshi, Abe Shinji, Setoguchi Yasuhiro. Serum Neutrophil Gelatinase-associated Lipocalin (NGAL) Is Elevated in Patients with Asthma and Airway Obstruction CURRENT MEDICAL SCIENCE. 2021.04; 41 (2): 323-328. ( PubMed, DOI )
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Matsumoto Y., Abe N., Tobita R., Kawakami H., Nakayama H., Setoguchi Y., Tsuboi R., Okubo Y.. The risk of interstitial lung disease during biological treatment in Japanese patients with psoriasis CLINICAL AND EXPERIMENTAL DERMATOLOGY. 2020.10; 45 (7): 853-858. ( DOI )
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Setoguchi Yasuhiro, Miyazaki Yasunari, Nakayama Yoshiki, Matsuyama Len, Ando Mari, Matsuba Seiji, Uchida Masaki. Development of image processing-based smartphone App (Application Software) for self-management of inhaled medicines for patients with asthma or COPD EUROPEAN RESPIRATORY JOURNAL. 2020.09; 56 ( DOI )
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Yajima C, Kokuho N, Toriyama K, Kawagoe J, Togashi Y, Matsubayashi J, Nakayama H, Setoguchi Y, Abe S. A case of imatinib-related obstructive bronchiolitis followed long term. Respiratory medicine case reports. 2020; 30 101052. ( PubMed, DOI )
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Takezaki Akio, Tsukumo Shin-ichi, Setoguchi Yasuhiro, Ledford Julie G., Goto Hisatsugu, Hosomichi Kazuyoshi, Uehara Hisanori, Nishioka Yasuhiko, Yasutomo Koji. A homozygous SFTPA1 mutation drives necroptosis of type II alveolar epithelial cells in patients with idiopathic pulmonary fibrosis JOURNAL OF EXPERIMENTAL MEDICINE. 2019.12; 216 (12): 2724-2735. ( PubMed, DOI )
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Kasagi Satoshi, Tomita Yasuhiro, Takaya Hisashi, Setoguchi Yasuhiro, Narui Koji. IMPACT OF AGING ON SLEEP DISORDERED BREATHING RESPIROLOGY. 2019.11; 24 209-210.
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Setoguchi Yasuhiro, Kitagawa Sayoko, Katayanagi Shinji, Okamoto T., Miyazaki Yasunari. SERUM GALECTIN-3 COULD BE USEFUL BIOMARKER TO KNOW PROGRESSION OF PULMONARY FIBROSIS RESPIROLOGY. 2019.11; 24 90.
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Inoue Y., Yamaguchi E., Setoguchi Y., Ichiwata T., Ebina M., Cho K., Tazawa R., Ishii H., Kasai T., Akira M., Arai T., Uchida K., Kida H., Morimoto K., Kitaichi M., Hatsuda K., Sugimoto C., Hirose M., Nakata K.. Prognostic Impacts of Comorbidities in Pulmonary Alveolar Proteinosis: A Nationwide Surveillance in Japan AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2019; 199
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Setoguchi Y., Ishiwari M., Kawagoe J., Toriyama K., Kitagawa S.. Clinical, Pulmonary Physiological and Genetic Characteristics in Adult-Onset Familial Interstitial Pneumonia (FIP) AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2018; 197
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Setoguchi Y., Kawagoe J., Kotagawa S.. Characteristics Of Age At Onset In Adult-Onset Hereditary Interstitial Pneumonia (hip) AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2017; 195
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Kasagi S., Narui K., Kawagoe J., Fujiwara A., Sugiyama S., Togashi Y., Yamakoshi S., Nakayama H., Setoguchi Y.. RELATIONSHIPS BETWEEN SLEEP BREATHING DISORDERS AND IMPAIRMENT OF PULMONARY FUNCTION IN INTERSTITIAL PNEUMONIA RESPIROLOGY. 2016.11; 21 196.
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Nakayama H., Kobayashi M., Yanagihara M., Tsuiki S., Kasagi S., Inoue Y., Setoguchi Y.. Three distinct subgroups of male obstructive sleep apnoea patients by cluster analysis based on polysomnographic variables JOURNAL OF SLEEP RESEARCH. 2016.09; 25 257.
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Ohbayashi Hiroyuki, Setoguchi Yasuhiro, Fukuchi Yoshinosuke, Shibata Kai, Sakata Yukinori, Arai Toshihisa. Pharmacological effects of lysozyme on COPD and bronchial asthma with sputum: A randomized, placebo-controlled, small cohort, cross-over study PULMONARY PHARMACOLOGY & THERAPEUTICS. 2016.04; 37 73-80. ( PubMed, DOI )
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Yamakoshi Shiho, Kasai Takatoshi, Tomita Yasuhiro, Takaya Hisashi, Kasagi Satoshi, Kawabata Masateru, Narui Koji, Setoguchi Yasuhiro. Comparison of clinical features and polysomnographic findings between men and women with sleep apnea JOURNAL OF THORACIC DISEASE. 2016.01; 8 (1): 145-151. ( PubMed, DOI )
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Kasagi Satoshi, Narui Koji, Kawagoe Junichiro, Fujiwara Akahito, Sugiyama Shinya, Yamakoshi Shiho, Togashi Yuki, Nakayama Hideaki, Setoguchi Yasuhiro. RELATIONSHIP BETWEEN SLEEP APNOEA SYNDROME AND IMPAIRMENT OF PULMONARY FUNCTION IN CHRONIC RESPIRATORY DISEASES RESPIROLOGY. 2015.12; 20 49.
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Setoguchi Yasuhiro, Izumi Shinyu, Nakamura Hidenori, Hanada Shigeo, Marumo Kazuyoshi, Kurosaki Atsuko, Akata Shouichi. Survey to determine the efficacy and safety of guideline-based pharmacological therapy for chronic obstructive pulmonary disease patients not previously receiving maintenance treatment EXPERT OPINION ON PHARMACOTHERAPY. 2015.10; 16 (15): 2271-2281. ( PubMed, DOI )
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Okuma Yusuke, Tanuma Junko, Kamiryo Hiroshi, Kojima Yuki, Yotsumoto Mihoko, Ajisawa Atsushi, Uehira Tomoko, Nagai Hirokazu, Takeda Yuichiro, Setoguchi Yasuhiro, Okada Seiji. A multi-institutional study of clinicopathological features and molecular epidemiology of epidermal growth factor receptor mutations in lung cancer patients living with human immunodeficiency virus infection JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY. 2015.09; 141 (9): 1669-1678. ( PubMed, DOI )
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Nakayama Hideaki, Kobayashi Mika, Yanagihara Mariko, Ito Eiki, Tsuiki Satoru, Kasagi Satoshi, Setoguchi Yasuhiro, Inoue Yuuichi. Are respiratory events and/or arousals during each sleep stage different by upper airway collapsibility? EUROPEAN RESPIRATORY JOURNAL. 2015.09; 46 ( DOI )
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Nakajima Fukami, Aratani Satoko, Fujita Hidetoshi, Yagishita Naoko, Ichinose Shizuko, Makita Koshi, Setoguchi Yasuhiro, Nakajima Toshihiro. Synoviolin inhibitor LS-102 reduces endoplasmic reticulum stress-induced collagen secretion in an in vitro model of stress-related interstitial pneumonia INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2015.01; 35 (1): 110-116. ( PubMed, DOI )
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Setoguchi Y.. Indactaterol Mono- And Combination Therapy With Inhaled Tiotropium Bromide In COPD: A 52-Week Study AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2015; 191
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Okuma Y., Tanuma J., Otera H., Kojima Y., Yotsumoto M., Uehira T., Takeda Y., Nagai H., Ajisawa A., Setoguchi Y., Okada S.. A MULTI-INSTITUTIONAL SURVEILLANCE OF CLINICOPATHOLOGICAL FEATURES AND MOLECULAR EPIDEMIOLOGY OF EGFR MUTATIONS IN LUNG CANCER PATIENTS LIVING WITH HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN JAPAN ANNALS OF ONCOLOGY. 2014.09; 25 ( DOI )
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Nakayama H., Kobayashi M., Yanagihara M., Ito E., Kasagi S., Setoguchi Y., Inoue Y.. Do sleep stages affect the occurrence of respiratory events with arousals? JOURNAL OF SLEEP RESEARCH. 2014.09; 23 199.
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Setoguchi Y., Izumi S., Hanada G., Nakamura H., Marumo K.. The Effects And Safety Of Standard Therapy For COPD Patients Who Were Not Previously Receiving Maintenance Treatment AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2014; 189
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Fujiwara Akahito, Tsushima Kenji, Sugiyama Shinya, Yamaguchi Koichi, Soeda Seiko, Togashi Yuki, Kono Yuta, Kasagi Satoshi, Setoguchi Yasuhiro. Histological types and localizations of lung cancers in patients with combined pulmonary fibrosis and emphysema THORACIC CANCER. 2013.11; 4 (4): 354-360. ( PubMed, DOI )
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Kitazawa Hiroshi, Moriya Kunihiko, Niizuma Hidetaka, Kawano Kengo, Saito-Nanjo Yuka, Uchiyama Toru, Rikiishi Takeshi, Sasahara Yoji, Sakamoto Osamu, Setoguchi Yasuhiro, Kure Shigeo. Interstitial lung disease in two brothers with novel compound heterozygous ABCA3 mutations EUROPEAN JOURNAL OF PEDIATRICS. 2013.07; 172 (7): 953-957. ( PubMed, DOI )
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Kono Yuta, Tsushima Kenji, Yamaguchi Koichi, Kurita Nao, Soeda Seiko, Fujiwara Akahito, Sugiyama Shinya, Togashi Yuki, Kasagi Satoshi, To Masako, To Yasuo, Setoguchi Yasuhiro. The utility of galactomannan antigen in the bronchial washing and serum for diagnosing pulmonary aspergillosis RESPIRATORY MEDICINE. 2013.07; 107 (7): 1094-1100. ( PubMed, DOI )
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Soeda Seiko, Ohyashiki Junko H., Ohtsuki Kazushige, Umezu Tomohiro, Setoguchi Yasuhiro, Ohyashiki Kazuma. Clinical relevance of plasma miR-106b levels in patients with chronic obstructive pulmonary disease INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2013.03; 31 (3): 533-539. ( PubMed, DOI )
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Yamaguchi K, Tsushima K, Kurita N, Fujiwara A, Soeda S, Yamaguchi A, Sugiyama S, Togashi Y, Kono Y, Kasagi S, Setoguchi Y. Clinical characteristics classified by the serum KL-6 level in patients with organizing pneumonia. Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG. 2013.03; 30 (1): 43-51. ( PubMed )
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Yamaguchi K., Tsushima K., Kurita N., Fujiwara A., Soeda S., Yamaguchi A., Sugiyama S., Togashi Y., Kono Y., Kasagi S., Setoguchi Y.. CLINICAL CHARACTERISTICS CLASSIFIED BY THE SERUM KL-6 LEVEL IN PATIENTS WITH ORGANIZING PNEUMONIA SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES. 2013; 30 (1): 43-51.
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Inoue Y., Arai T., Nakata K., Yamaguchi E., Ichiwata T., Ebina M., Tazawa R., Ishii H., Setoguchi Y., Kitaichi M., Akira M., Tatsumi K., Nasuhara Y., Cho K., Tsuchihashi Y., Uchida K., Takada T., Nakayama H., Tomii K., Sugimoto C., Kohashi Y., Ohkouchi S., Kasahara Y., Morimoto K., Nakatani T., Tsuyuguchi K.. Longitudinal Cohort Of Autoimmune Pulmonary Alveolar ProteINOSis AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2013; 187
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Kuse N., Abe S., Hayashi H., Kamio K., Saito Y., Azuma A., Kudoh S., Kunugi S., Fukuda Y., Setoguchi Y., Gemma A.. FAMILIAL INTERSTITIAL PNEUMONIA IN AN ADOLESCENT BOY WITH SURFACTANT PROTEIN C GENE (Y104H) MUTATION SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES. 2013; 30 (1): 73-77.
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Iwai Kazuro, Soejima Kenzo, Kudoh Shoji, Umezato Yoshimasa, Kaneko Toru, Yoshimori Kouji, Tokuda Hitoshi, Yamaguchi Tetsuo, Mizoo Akira, Setoguchi Yasuhiro, Kamigaki Takashi, Fujimoto Katsunada, Goto Shigenori. Extended survival observed in adoptive activated T lymphocyte immunotherapy for advanced lung cancer: results of a multicenter historical cohort study CANCER IMMUNOLOGY IMMUNOTHERAPY. 2012.10; 61 (10): 1781-1790. ( PubMed, DOI )
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Inoue Yoshikazu, Nakata Koh, Arai Toru, Yamaguchi Etsuro, Ichiwata Toshio, Ebina Masahito, Tazawa Ryushi, Ishii Haruyuki, Setoguchi Yasuhiro, Kitaichi Masanori, Akira Masanori, Tatsumi Koichiro, Nasuhara Yasuyuki, Cho Kazutoshi, Tsuchihashi Yoshiko, Uchida Kanji, Takada Toshinori, Nakayama Hideaki, Tomii Keisuke, Sugimoto Chikatoshi, Kohashi Yasuo, Ohkouchi Shinya, Kasahara Yasunori, Morimoto Kohnosuke, Sakamoto Naoko. Occupational and environmental impact on the clinical course of autoimmune pulmonary alveolar proteinosis EUROPEAN RESPIRATORY JOURNAL. 2012.09; 40
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Saito Masuyoshi, Yamazaki Masashi, Maeda Tatsuo, Matsumura Hajime, Setoguchi Yasuhiro, Tsuboi Ryoji. Pirfenidone suppresses keloid fibroblast-embedded collagen gel contraction ARCHIVES OF DERMATOLOGICAL RESEARCH. 2012.04; 304 (3): 217-222. ( PubMed, DOI )
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Isobe Yasushi, Aritaka Nanae, Setoguchi Yasuhiro, Ito Yoshinori, Kimura Hiroshi, Hamano Yasuharu, Sugimoto Koichi, Komatsu Norio. T/NK cell type chronic active Epstein-Barr virus disease in adults: an underlying condition for Epstein-Barr virus-associated T/NK-cell lymphoma JOURNAL OF CLINICAL PATHOLOGY. 2012.03; 65 (3): 278-282. ( PubMed, DOI )
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Kono Y, Tsushima K, Yamaguchi K, Soeda S, Fujiwara A, Sugiyama S, Togashi Y, Kasagi S, Setoguchi Y. The relationship between the clinical course and cytokine in a patient with cigarette smoking-induced acute eosinophilic pneumonia - A case report. Respiratory medicine case reports. 2012; 5 16-9. ( PubMed, DOI )
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Abe Tetsuya, Setoguchi Yasuhiro, Kono Yuta, Togashi Yuhki, Sugiyama Shinya, Tanakadate Motochika, Soeda Seiko, Nakai Michiko, Sugiyama Norihiro, Fujiwara Akahito, Yamaguchi Kouichi, Yamaguchi Aya, Kurita Nao. Effects of inhaled tiotropium plus transdermal tulobuterol versus tiotropium alone on impulse oscillation system (IOS)-assessed measures of peripheral airway resistance and reactance, lung function and quality of life in patients with COPD: A randomized crossover study PULMONARY PHARMACOLOGY & THERAPEUTICS. 2011.10; 24 (5): 617-624. ( PubMed, DOI )
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河野 雄太, 阿部 哲也, 松林 純, 長尾 俊孝, 瀬戸口 靖弘. サルコイドーシスにおける閉塞性換気障害とVEGFの関連性の検討(Vascular endothelial growth factor (VEGF) plays a role in causing airflow limitation in sarcoidosis) 東京医科大学雑誌. 2011.04; 69 (2): 219-226. ( 医中誌 )
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Fujieda Yoshiharu, Ambe Hisataka, Suijo Kenichi, Takahara Katsura, Setoguchi Yugo. Resistance Training With Electrical-loading Machines Can Improve Complex Fitness And Atherosclerotic Risks In Elderly Japanese MEDICINE AND SCIENCE IN SPORTS AND EXERCISE. 2010.05; 42 (5): 414.
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Ohtaka Jun, Komatsu Shunsuke, Kurita Nao, Kume Seiko, Kono Yuta, Setoguchi Yasuhiro. サーファクタント蛋白質C遺伝子(SFTPC)変異は小児間質性肺疾患(PILD)進展の原因因子である(Mutations in the surfactant protein C gene (SFTPC) could be causative factor in developing pediatric interstitial lung disease (PILD)) 日本呼吸器学会雑誌. 2010.03; 48 (増刊): 415. ( 医中誌 )
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Setoguchi Y., Kume S., Kono Y., Togashi Y.. Mutations In The Surfactant Protein C (SFTPC) Gene Encoding Non-BRICHOS Domain Could Be Linked To Developing Sporadic Infant-onset Interstitial Lung Disease AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2010; 181
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Watanabe M, Takata Y, Fukasawa S, Sakota K, Abe T, Goseki Y, Setoguchi Y, Chikamori T, Yamashina A. Two patients with bepridil-induced interstitial pneumonia. Circulation journal : official journal of the Japanese Circulation Society. 2009.07; 73 (7): 1352-5. ( PubMed, DOI )
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Kuwabara Rika, Tamaoki Fukami, Nakai Michiko, Kono Yuta, Setoguchi Yasuhiro. 小児間質性肺疾患(PILD)においてサーファクタント蛋白質C(SFTPC)変異は高頻度と推測される(Mutations in the surfactant protein C (SFTPC) are predicted to be high frequency in pediatric interstitial lung diseases (PILD)) 日本呼吸器学会雑誌. 2009.05; 47 (増刊): 343. ( 医中誌 )
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Setoguchi Y., Tamaoki F., Nakai M., Kono Y.. The Frequency of Mutations in the Surfactant Protein C Gene (SFTPC) Is Much Higher in Pediatric Interstitial Lung Disease (PILD) Than Either Adult-Onset Familial or Sporadic Interstitial Pneumonia (IP) AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2009; 179
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大久保 仁嗣, 瀬戸口 靖弘, 小林 裕子, 金ヶ崎 士朗, 大屋敷 一馬, 玉谷 卓也. 間質性肺疾患の肺胞マクロファージにガレクチン-9は過剰に発現する(Increased galectin-9 expression in alveolar macrophages in interstitial lung disease) 東京医科大学雑誌. 2008.10; 66 (4): 513-521. ( 医中誌 )
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Tamaoki Fukami, Kono Yuta, Setoguchi Yasuhiro. サーファクタント蛋白質C遺伝子(SFTPC)における新規変異により生じた非特異的間質性肺炎と肺胞蛋白症(Nonspecific Interstitial Pneumonia and Alveolar Proteinosis Trafficking Resulting From A Novel Mutation in The Surfactant Protein C Gene(SFTPC)) 日本呼吸器学会雑誌. 2008.05; 46 (増刊): 365. ( 医中誌 )
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Nakai Michiko, Kono Yuta, Abe Tetsuya, Sugiyama Norihiro, Setoguchi Yasuhiro. 間質性肺炎(IP)の日本人患者のサーファクタント蛋白質C遺伝子(SFTPC)の新規変異の臨床病理学的意義(Clinico-Pathological Consequences of Novel Mutations in The Surfactant Protein C Gene(SFTPC) in Japanese Patients with Interstitial Pneumonia(IP)) 日本呼吸器学会雑誌. 2008.05; 46 (増刊): 360. ( 医中誌 )
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Jankipersadsing Vishant, Tauchi Tetsuzo, Tanaka Yuko, Setoguchi Yasuhiro, Mukai Kiyoshi, Ohyashiki Kazuma. Spontaneous regression of pulmonary infiltration of adult T-Cell leukemia/lymphoma INTERNATIONAL JOURNAL OF HEMATOLOGY. 2007.10; 86 (3): 207. ( DOI )
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Jankipersadsing V, Tauchi T, Ohyashiki K, Tanaka Y, Setoguchi Y, Mukai K. Spontaneous regression of pulmonary infiltration of adult T-cell leukemia/lymphoma. International journal of hematology. 2007.10; 86 (3): 207. ( PubMed, DOI )
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Setoguchi Yasuhiro. 稀少肺疾患の病態と治療 間質性肺炎患者におけるサーファクタント蛋白CとATP Binding Cassette membrane transporter A3(ABCA3)遺伝子の新しい変異の同定および臨床結果(Identification of novel mutations of surfactant protein C and ABCA 3 gene in patients with interstitial pneumonia and the clinical consequences) 日本呼吸器学会雑誌. 2007.04; 45 (増刊): 55. ( 医中誌 )
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Setoguchi Y, Ikeda T, Fukuchi Y. Clinical features and genetic analysis of surfactant protein C in adult-onset familial interstitial pneumonia. Respirology (Carlton, Vic.). 2006.01; 11 Suppl S41-5. ( PubMed, DOI )
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Setoguchi Y, Ikeda T, Fukuchi Y. Clinical features and genetic analysis of surfactant protein C in adult-onset familial interstitial pneumonia RESPIROLOGY. 2006.01; 11 S41-S45.
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Yokoyama T, Setoguchi Y, Ohta K, Sugiyama N, Nagate A, Nagao T, Ohyashiki K. Endobronchial minute leiomyoma in a patient with malignant lymphoma. Internal medicine (Tokyo, Japan). 2005.07; 44 (7): 769-70. ( PubMed, DOI )
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Yokoyama T, Setoguchi Y, Ohta K, Sugiyama N, Nagate A, Nagao T, Ohyashiki K. Endobronchial minute leiomyoma in a patient with malignant lymphoma INTERNAL MEDICINE. 2005.07; 44 (7): 769-770.
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Yokoyama Tomohisa, Setoguchi Yasuhiro, Ohta Kaori, Sugiyama Norihiro, Nagate Akira, Nagao Toshitaka, Ohyashiki Kazuma. 臨床医学における画像 悪性リンパ腫患者にみられた気管支内微小平滑筋症(PICTURES IN CLINICAL MEDICINE: Endobronchial Minute Leiomyoma in a Patient with Malignant Lymphoma) Internal Medicine. 2005.07; 44 (7): 769-770. ( 医中誌 )
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Sato T, Seyama K, Kumasaka T, Fujii H, Setoguchi Y, Shirai T, Tomino Y, Hino O, Fukuchi Y. A patient with TSC1 germline mutation whose clinical phenotype was limited to lymphangioleiomyomatosis JOURNAL OF INTERNAL MEDICINE. 2004.08; 256 (2): 166-173.
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Sumiyoshi K, Nakao A, Setoguchi Y, Okumura K, Ogawa H. Exogenous Smad3 accelerates wound healing in a rabbit dermal ulcer model JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2004.07; 123 (1): 229-236. ( PubMed, DOI )
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Sumiyoshi K, Nakao A, Setoguchi Y, Okumura K, Tsuboi R, Ogawa H. Smads regulate collagen gel contraction by human dermal fibroblasts BRITISH JOURNAL OF DERMATOLOGY. 2003.09; 149 (3): 464-470.
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Funaki T, Nakao A, Ebihara N, Setoguchi Y, Fukuchi Y, Okumura K, Ra C, Ogawa H, Kanai A. Smad7 suppresses the inhibitory effect of TGF-beta2 on corneal endothelial cell proliferation and accelerates corneal endothelial wound closure in vitro. Cornea. 2003.03; 22 (2): 153-9. ( PubMed, DOI )
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Funaki T, Nakao A, Ebihara N, Setoguchi Y, Fukuchi Y, Okumura K, Ra C, Ogawa H, Kanai A. Smad7 suppresses the inhibitory effect of TGF-beta 2 on corneal endothelial cell proliferation and accelerates corneal endothelial wound closure in vitro CORNEA. 2003.03; 22 (2): 153-159.
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Sumiyoshi K, Nakao A, Setoguchi Y, Tsuboi R, Okumura K, Ogawa H. TGF-beta/Smad signaling inhibits IFN-gamma and TNF-alpha-induced TARC (CCL17) production in HaCaT cells. Journal of dermatological science. 2003.02; 31 (1): 53-8. ( PubMed, DOI )
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Nakao A, Sagara H, Setoguchi Y, Okada T, Okumura K, Ogawa H, Fukuda T. Expression of Smad7 in bronchial epithelial cells is inversely correlated to basement membrane thickness and airway hyperresponsiveness in patients with asthma JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2002.12; 110 (6): 873-878. ( PubMed, DOI )
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Ogawara M, Takahashi M, Shimizu T, Nakajima M, Setoguchi Y, Shirasawa T. Adenoviral expression of protein-L-isoaspartyl methyltransferase (PIMT) partially attenuates the biochemical changes in PIMT-deficient mice JOURNAL OF NEUROSCIENCE RESEARCH. 2002.08; 69 (3): 353-361. ( PubMed, DOI )
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Manabe Y, Nagano I, Gazi MSA, Murakami T, Shiote M, Shoji M, Kitagawa H, Setoguchi Y, Abe K. Adenovirus-mediated gene transfer of glial cell line-derived neurotrophic factor prevents motor neuron loss of transgenic model mice for amyotrophic lateral sclerosis APOPTOSIS. 2002.08; 7 (4): 329-334.
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Sato Teruhiko, Seyama Kuniaki, Fujii Hiroaki, Maruyama Hiroshi, Setoguchi Yasuhiro, Iwakami Shin-ichiro, Fukuchi Yoshinosuke, Hino Okio. 肺リンパ管平滑筋腫症の日本人患者におけるTSC1及びTSC2遺伝子の変異解析(Mutation analysis of the TSC1 and TSC2 genes in Japanese patients with pulmonary lymphangioleiomyomatosis) Journal of Human Genetics. 2002.01; 47 (1): 20-28. ( 医中誌 )
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Sato T, Seyama K, Fujii H, Maruyama H, Setoguchi Y, Iwakami S, Fukuchi Y, Hino O. Mutation analysis of the TSC1 and TSC2 genes in Japanese patients with pulmonary lymphangioleiomyomatosis. Journal of human genetics. 2002; 47 (1): 20-8. ( PubMed, DOI )
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Sato T, Seyama K, Fujii H, Maruyama H, Setoguchi Y, Iwakami S, Fukuchi Y, Hino O. Mutation analysis of the TSC1 and TSC2 genes in Japanese patients with pulmonary lymphangioleiomyomatosis JOURNAL OF HUMAN GENETICS. 2002; 47 (1): 20-28.
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Kodama Y, Setoguchi Y, Fukuchi Y. Infection of replication-deficient adenoviral vector enhances interleukin-8 production in small airway epithelial cells more than in large airway epithelial cells. Respirology (Carlton, Vic.). 2001.12; 6 (4): 271-9. ( PubMed, DOI )
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Seino K, Setoguchi Y, Ogino T, Kayagaki N, Akiba H, Nakano H, Taniguchi H, Takada Y, Yuzawa K, Todoroki T, Fukuchi Y, Yagita H, Okumura K, Fukao K. Protection against Fas-mediated and tumor necrosis factor receptor 1-mediated liver injury by blockade of FADD without loss of nuclear factor-kappa B activation ANNALS OF SURGERY. 2001.11; 234 (5): 681-688.
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Murakami T, Nagano I, Hayashi T, Manabe Y, Shoji M, Setoguchi Y, Abe K. Impaired retrograde axonal transport of adenovirus-mediated E-coli LacZ gene in the mice carrying mutant SOD1 gene NEUROSCIENCE LETTERS. 2001.08; 308 (3): 149-152.
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Iwakami SI, Setoguchi Y, Saijo Y, Azuma M, Fukuchi Y. Replication-deficient adenovirus-mediated transfer of B7-1 (CD80) cDNA induces anti-tumour immunity in isolated human lung cancer. Respirology (Carlton, Vic.). 2001.06; 6 (2): 135-44. ( PubMed, DOI )
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Sakurai M, Abe K, Hayashi T, Setoguchi Y, Yaginuma G, Meguro T, Tabayashi K. Adenovirus-mediated glial cell line-derived neurotrophic factor gene delivery reduces motor neuron injury after transient spinal cord ischemia in rabbits JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY. 2000.12; 120 (6): 1148-1157.
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Kitagawa H, Sasaki C, Sakai K, Mori A, Mitsumoto Y, Mori T, Fukuchi Y, Setoguchi Y, Abe K. Adenovirus-mediated gene transfer of glial cell line-derived neurotrophic factor prevents ischemic brain injury after transient middle cerebral artery occlusion in rats JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 1999.12; 19 (12): 1336-1344.
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Sakurai M, Abe K, Hayashi T, Warita H, Setoguchi Y, Itoyama Y, Tabayashi K. In vivo adenovirus-mediated gene transfer and expression in ischemic rabbit spinal cord JOURNAL OF VASCULAR SURGERY. 1999.09; 30 (3): 542-550.
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Miyaguchi K, Maeda Y, Kojima T, Setoguchi Y, Mori N. Neuron-targeted gene transfer by adenovirus carrying neural-restrictive silencer element NEUROREPORT. 1999.08; 10 (11): 2349-2353.
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Osada S, Ebihara I, Setoguchi Y, Takahashi H, Tomino Y, Koide H. Gene therapy for renal anemia in mice with polycystic kidney using an adenovirus vector encoding the human erythropoietin gene KIDNEY INTERNATIONAL. 1999.04; 55 (4): 1234-1240.
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Setoguchi Y, Koiwai H, Kodama Y, Fukuchi Y. Human vascular endothelial cells have diverse hypoxia-response in HIF-dependent manner. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 1999.03; 159 (3): A567.
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Abe K, Kitagawa H, Setoguchi Y. Temporal profile of adenovirus-mediated E-colilacZ gene expression in normal and postischemic gerbil hippocampus and ventricle NEUROLOGICAL RESEARCH. 1998.12; 20 (8): 689-696.
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Kitagawa H, Setoguchi Y, Fukuchi Y, Mitsumoto Y, Koga N, Mori T, Abe K. Induction of DNA fragmentation and HSP72 immunoreactivity by adenovirus-mediated gene transfer in normal gerbil hippocampus and ventricle JOURNAL OF NEUROSCIENCE RESEARCH. 1998.10; 54 (1): 38-45.
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Kitagawa H, Setoguchi Y, Fukuchi Y, Mitsumoto Y, Koga N, Mori T, Abe K. DNA fragmentation and HSP72 gene expression by adenovirus-mediated gene transfer in postischemic gerbil hippocampus and ventricle METABOLIC BRAIN DISEASE. 1998.09; 13 (3): 211-223.
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Warita H, Abe K, Setoguchi Y, Itoyama Y. Expression of adenovirus-mediated E-coli lacZ gene in skeletal muscles and spinal motor neurons of transgenic mice with a mutant superoxide dismutase gene NEUROSCIENCE LETTERS. 1998.05; 246 (3): 153-156.
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Mogi S, Ebata T, Setoguchi Y, Fujime M, Heike Y, Kohsaka T, Yagita H, Okumura K, Azuma M. Efficient generation of autologous peripheral blood-derived cytotoxic T lymphocytes against poorly immunogenic human tumors using recombinant CD80-adenovirus together with interleukin 12 and interleukin 2 CLINICAL CANCER RESEARCH. 1998.03; 4 (3): 713-720.
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Abe K, Setoguchi Y, Hayashi T, Itoyama Y. In vivo adenovirus-mediated gene transfer and the expression in ischemic and reperfused rat brain BRAIN RESEARCH. 1997.07; 763 (2): 191-201.
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Abe K, Setoguchi Y, Hayashi T, Itoyama Y. Dissociative expression of adenoviral-mediated E-coli LacZ gene between ischemic and reperfused rat brains NEUROSCIENCE LETTERS. 1997.04; 226 (1): 53-56.
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OSADA S, SETOGUCHI Y, EBIHARA I, TAKAHASHI H, TOMINO Y, KOIDE H. IMPROVING RENAL ANEMIA OF DBA/2FG-PCY MICE FOLLOWING ADENOVIRUS-MEDIATED HUMAN ERYTHROPOIETIN CDNA TRANSFER IN-VIVO JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 1995.09; 6 (3): 1026.
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SETOGUCHI Y, DANEL C, CRYSTAL RG. STIMULATION OF ERYTHROPOIESIS BY IN-VIVO GENE-THERAPY - PHYSIOLOGICAL CONSEQUENCES OF TRANSFER OF THE HUMAN ERYTHROPOIETIN GENE TO EXPERIMENTAL-ANIMALS USING AN ADENOVIRUS VECTOR BLOOD. 1994.11; 84 (9): 2946-2953.
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SETOGUCHI Y, JAFFE HA, DANEL C, CRYSTAL RG. EX-VIVO AND IN-VIVO GENE-TRANSFER TO THE SKIN USING REPLICATION-DEFICIENT RECOMBINANT ADENOVIRUS VECTORS JOURNAL OF INVESTIGATIVE DERMATOLOGY. 1994.04; 102 (4): 415-421.
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SETOGUCHI Y, JAFFE HA, CHU CS, CRYSTAL RG. INTRAPERITONEAL IN-VIVO GENE-THERAPY TO DELIVER ALPHA-1-ANTITRYPSIN TO THE SYSTEMIC CIRCULATION AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 1994.04; 10 (4): 369-377.
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SETOGUCHI Y, JAFFE HA, HORIAGON T, CHU CS, CRYSTAL RG. INVIVO GENE-THERAPY TARGETING THE PERITONEUM FOR ALPHA-1-ANTITRYPSIN DEFICIENCY AMERICAN REVIEW OF RESPIRATORY DISEASE. 1993.04; 147 (4): A546.
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SETOGUCHI Y, DANEL C, CRYSTAL RG. STIMULATION OF ERYTHROPOIESIS BY INVIVO GENE-THERAPY - PHYSIOLOGICAL CONSEQUENCE OF TRANSFER OF THE HUMAN ERYTHROPOIETIN GENE TO EXPERIMENTAL-ANIMALS USING AN ADENOVIRUS VECTOR CLINICAL RESEARCH. 1993.04; 41 (2): A259.
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JAFFE HA, DANEL C, LONGENECKER G, METZGER M, SETOGUCHI Y, ROSENFELD MA, GANT TW, THORGEIRSSON SS, STRATFORDPERRICAUDET LD, PERRICAUDET M, PAVIRANI A, LECOCQ JP, CRYSTAL RG. ADENOVIRUS-MEDIATED INVIVO GENE-TRANSFER AND EXPRESSION IN NORMAL RAT-LIVER NATURE GENETICS. 1992.08; 1 (5): 372-378. ( PubMed, DOI )
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JAFFE HA, DANEL C, LONGENECKER G, METZGER M, SETOGUCHI Y, ROSENFELD MA, GANT TW, THORGEIRSSON SS, STRATFORDPERRICAUDET LD, PERRICAUDET M, PAVIRANI A, LECOCQ JP, CRYSTAL RG. INVIVO GENE-TRANSFER TO LIVER - ADENOVIRUS-MEDIATED TRANSFER AND EXPRESSION OF EXOGENOUS GENES IN NORMAL RAT-LIVER CLINICAL RESEARCH. 1992.04; 40 (2): A252.
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SETOGUCHI Y, TAKAHASHI S, NUKIWA T, KIRA S. DETECTION OF HUMAN T-CELL LYMPHOTROPIC VIRUS TYPE I-RELATED ANTIBODIES IN PATIENTS WITH LYMPHOCYTIC INTERSTITIAL PNEUMONIA AMERICAN REVIEW OF RESPIRATORY DISEASE. 1991.12; 144 (6): 1361-1365. ( PubMed, DOI )
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TAKAHASHI S, SETOGUCHI Y, NUKIWA T, KIRA S. SOLUBLE INTERLEUKIN-2 RECEPTOR IN SERA OF PATIENTS WITH PULMONARY TUBERCULOSIS CHEST. 1991.02; 99 (2): 310-314. ( PubMed, DOI )
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瀬戸口 靖弘. 【びまん性肺疾患-病態・臨床の最新知見-】診断と治療 特発性間質性肺炎 家族性間質性肺炎の臨床と遺伝子変異 日本臨床. 2022.09; 80 (9): 1415-1424. ( 医中誌 )
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Ohta K, Yokoyama T, Abe T, Kurakawa E, Park J, Izumi M, Eishi Y, Ohyashiki K, Setoguchi Y. [Identification of propionibacterium acnes in a case with stage III pulmonary sarcoidosis involving hepatosplenic disease]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society. 2006.09; 44 (9): 625-30. ( PubMed )
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太田 香織, 横山 智央, 阿部 哲也, 庫川 恵理, 朴 辰浩, 泉 美貴, 江石 義信, 大屋敷 一馬, 瀬戸口 靖弘. 肉芽腫内にP.acnes菌体成分を認め、肝臓・脾臓病変を伴った肺野型サルコイドーシス 日本呼吸器学会雑誌. 2006.09; 44 (9): 625-630. ( 医中誌 )
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瀬戸口 靖弘. 【サーファクタント蛋白の分子機構解明は臨床をどう変えるのか】家族性間質性肺炎におけるSP-C遺伝子変異解析の現況 分子呼吸器病. 2006.05; 10 (3): 176-182. ( 医中誌 )
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Setoguchi Y, Yokoyama T. [Cystic fibrosis and gene therapy]. Nihon rinsho. Japanese journal of clinical medicine. 2005.12; 63 Suppl 12 607-16. ( PubMed )
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杉山 憲弘, 横山 智央, 太田 香織, 長手 聰, 指田 吾郎, 峯村 和成, 瀬戸口 靖弘, 大屋敷 一馬, 干川 就可. 脳原発悪性リンパ腫治療後に肺病変(diffuse large B-cell lymphoma)を合併し,自然消退傾向を示した1例 日本内科学会関東地方会. 2005.06; 527回 20. ( 医中誌 )
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瀬山 邦明, 佐藤 輝彦, 熊坂 利夫, 藤井 博昭, 相馬 早苗, 三谷 恵子, 瀬戸口 靖弘, 樋野 興夫, 福地 義之助. de novo TSC1胚細胞遺伝子変異を認め,その表現型がリンパ脈管筋腫症に限られていた結節性硬化症の一例 家族性腫瘍. 2004.05; 4 (2): A34. ( 医中誌 )
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瀬戸口 靖弘, 池田 智美, 福地 義之助, 中村 眞二, 中尾 篤人. 肺線維化に対する再生修復関連分子の役割と制御についての分子遺伝学的検討 平成14年度 Smad7はTGF-βによる肺線維芽細胞のmyofibroblastへのphenotypic modulationを抑制する 順天堂医学. 2003.09; 49 (3): 361. ( 医中誌 )
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瀬戸口 靖弘, 池田 智美, 鈴木 孝次, 児玉 裕三, 井上 恵美, 福地 義之助. Smad 3過剰発現による肺線維芽細胞由来のゲル収縮増強は,MAP kinase pathwayを介するα-smooth muscle actin(a-SMA)発現増強に由来する 日本呼吸器学会雑誌. 2003.03; 41 (増刊): 87. ( 医中誌 )
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瀬戸口 靖弘, 池田 智美, 鈴木 孝次, 木戸 健治, 宮地 敦子, 福地 義之助. Smad 7はTGF-βによる肺線維芽細胞のmyofibroblastへのphenotypic modulationを抑制する 日本呼吸器学会雑誌. 2003.03; 41 (増刊): 87. ( 医中誌 )
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Nagaoka T, Setoguchi Y, Muramatsu M, Honma N, Danbara T, Miyamoto H, Izumi H, Uekusa T, Fukuchi Y. [A case of pulmonary squamous cell carcinoma coexisting with pulmonary actinomycosis]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society. 2002.06; 40 (6): 525-9. ( PubMed )
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佐藤 輝彦, 瀬山 邦明, 児玉 裕三, 玉木 ゆみ, 善場 元美, 大西 正浩, 家永 浩樹, 瀬戸口 靖弘, 鈴木 勉, 植木 純, 檀原 高, 吉良 枝郎, 福地 義之助. 肺リンパ脈管筋腫症(pulmonary lymphangioleiomyomatosis;LAM)に合併する自然気胸の臨床的意義 日本呼吸器学会雑誌. 2001.09; 39 (9): 656-663. ( 医中誌 )
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Setoguchi Y, Fukuchi Y. [Gene therapy for pulmonary hypertension]. Nihon rinsho. Japanese journal of clinical medicine. 2001.06; 59 (6): 1151-8. ( PubMed )
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小河原 緑, 瀬戸口 靖弘, 清水 孝彦, 高橋 真由美, 白澤 卓二. Protein L-Isoaspartyl Methyltransferase(PIMT)欠損マウス由来初代培養神経細胞に対する遺伝子治療 生化学. 1999.08; 71 (8): 1003. ( 医中誌 )
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Setoguchi Y, Tamaki Y, Oka M, Kira S. [Transfer of endothelial nitric oxide synthase gene in the purpose of gene therapy for pulmonary arterial hypertension]. Nihon rinsho. Japanese journal of clinical medicine. 1996.02; 54 (2): 369-76. ( PubMed )
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瀬戸口 靖弘. 気道上皮細胞への遺伝子導入 Molecular Medicine. 1995.07; 32 (8): 864-874. ( 医中誌 )
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Setoguchi Y, Noto K, Iwakami S, Tajima M, Kira S. [Gene transfer to airway epithelial cells: current status and future direction]. Nihon Kyobu Shikkan Gakkai zasshi. 1994.12; 32 Suppl 86-95. ( PubMed )
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貫和 敏博, 瀬戸口 靖弘. パラコート肺障害 医学のあゆみ. 1991.04; 別冊 (呼吸器疾患 state of arts): 62-64. ( 医中誌 )
講演・口頭発表等 【 表示 / 非表示 】
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瀬戸口 靖弘, 片柳 真司, 宮崎 泰成. SFTPA1/SFTPA2変異を有する間質性肺炎の臨床像と病態. 日本肺サーファクタント・界面医学会雑誌 2023.08.01
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瀬戸口 靖弘. 間質性肺炎の発症機序,進展を探る. 日本呼吸器学会誌 2023.03.01
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瀬戸口 靖弘, 島村 貴史, 伊藤 優, 片柳 真司, 宮崎 泰成. びまん性肺疾患 病因・病態1 SFTPA1/SFTPA2変異を有する間質性肺炎の臨床像と分子病態の特徴. 日本呼吸器学会誌 2023.03.01
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瀬戸口 靖弘, 北川 佐代子, 片柳 慎司, 森 由弘, 宮崎 泰成. びまん性肺疾患 線維化の病態 Telomerase関連遺伝子変異を有するPF-ILDの臨床的特徴. 日本呼吸器学会誌 2022.04.01
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瀬戸口 靖弘. 肺線維化進展の機序はどこまで明らかになってきたか. 日本肺サーファクタント・界面医学会雑誌 2021.10.01
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「 慢性過敏性肺炎における肺の線維化に関わる遺伝子を発見 」― TOLLIPの一塩基多型が呼吸機能の早期悪化に関連 ―,2021年08月
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