基本情報

写真a

田中 ゆきえ(タナカ ユキエ)

TANAKA Yukie


職名

助教

出身学校 【 表示 / 非表示

  • 東京医科歯科大学  医学部  保健衛生学科  卒業

出身大学院 【 表示 / 非表示

  • 大阪大学  医学系研究科  分子病態医学専攻  博士課程  修了

取得学位 【 表示 / 非表示

  • 博士(医学)  大阪大学

経歴(学内) 【 表示 / 非表示

  • 2017年08月
    -
    2020年09月
    東京医科歯科大学 統合研究機構 研究基盤クラスター 医歯学研究支援センター リサーチコアセンター 助教
  • 2020年10月
    -
    現在
    東京医科歯科大学 統合研究機構 研究基盤クラスター 医歯学研究支援センター リサーチコアセンター 助教

経歴(学外) 【 表示 / 非表示

  • 大阪大学 機能診断学 特任研究員
  • 東京大学医科学研究所 先端医療研究センター・分子療法分野 特任研究員
  • 自治医科大学 さいたま医療センター ポストドクター
  • 自治医科大学 さいたま医療センター リサーチ・レジデント
  • 2017年07月
    -
    現在
    東京大学医科学研究所 先端医療研究センター 分子療法分野 客員研究員

所属学協会 【 表示 / 非表示

  • 日本血液疾患免疫療法学会

  • 日本がん免疫学会

  • 日本血液学会

研究分野 【 表示 / 非表示

  • 免疫学

資格、免許 【 表示 / 非表示

  • 臨床検査技師

 

研究テーマ 【 表示 / 非表示

  • HTLV-1関連疾患におけるウイルス特異的細胞傷害性T細胞の性状解析 (研究責任者),2018年05月 - 現在

  • 移植後の日和見感染症に対する特異的T細胞療法の開発と臨床応用に関する研究,2016年04月 - 現在

競争的資金等の研究課題 【 表示 / 非表示

  • ATL発症阻止における幹細胞様メモリーT細胞の役割の解明と治療応用

    文部科学省/日本学術振興会 : 2018年 - 2020年

論文・総説 【 表示 / 非表示

  1. Nagano K, Tani-Sassa C, Iwasaki Y, Takatsuki Y, Yuasa S, Takahashi Y, Nakajima J, Sonobe K, Ichimura N, Nukui Y, Takeuchi H, Tanimoto K, Tanaka Y, Kimura A, Tohda S. SARS-CoV-2 R.1 lineage variants prevailed in Tokyo in March 2021. Journal of medical virology. 2021.07; ( PubMed, DOI )

  2. Oba S, Hosoya T, Amamiya M, Mitsumura T, Kawata D, Sasaki H, Kamiya M, Yamamoto A, Ando T, Shimada S, Shirai T, Okamoto T, Tateishi T, Endo A, Aiboshi J, Nosaka N, Yamanouchi H, Ugawa T, Nagaoka E, Oi K, Tao S, Maejima Y, Tanaka Y, Tanimoto K, Takeuchi H, Tohda S, Hirakawa A, Sasano T, Arai H, Otomo Y, Miyazaki Y, Yasuda S. Arterial and Venous Thrombosis Complicated in COVID-19: A Retrospective Single Center Analysis in Japan. Frontiers in cardiovascular medicine. 2021; 8 767074. ( PubMed, DOI )

  3. Kawamura K, Tanaka Y, Nakasone H, Ishihara Y, Kako S, Kobayashi S, Tanaka Y, Ohmori T, Uchimaru K, Okamoto S, Mineno J, Shiku H, Nishimura S, Kanda Y. Development of a unique T-cell receptor gene-transferred Tax-redirected T-cell immunotherapy for adult T-cell leukemia. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2020.04; ( PubMed, DOI )

  4. Nishiyama-Fujita Y, Kawana-Tachikawa AI, Ono T, Tanaka Y, Kato T, Heslop HE, Morio T, Takahashi S. Generation of multivirus-specific T cells by a single stimulation of peripheral blood mononuclear cells with a peptide mixture using serum-free medium. Tanaka Y. 2018.08; ( PubMed, DOI )

  5. Yuko Ishihara, Yukie Tanaka, Seiichiro Kobayashi, Koji Kawamura, Hideki Nakasone, Ayumi Gomyo, Jin Hayakawa, Masaharu Tamaki, Yu Akahoshi, Naonori Harada, Machiko Kusuda, Kazuaki Kameda, Tomotaka Ugai, Hidenori Wada, Kana Sakamoto, Miki Sato, Kiriko Terasako-Saito, Misato Kikuchi, Shun-Ichi Kimura, Aki Tanihara, Shinichi Kako, Kaoru Uchimaru, Yoshinobu Kanda. A unique T cell receptor amino acid sequence selected by HTLV-I Tax301-309-specific cytotoxic T-cells in HLA-A24:02(+) asymptomatic carriers and adult T-cell leukemia/lymphoma patients. J. Virol.. 2017.07; ( PubMed, DOI )

  6. Miki Sato, Shinichi Kako, Kana Matsumoto, Kumi Oshima, Yu Akahoshi, Hirofumi Nakano, Tomotaka Ugai, Ryoko Yamasaki, Hidenori Wada, Yuko Ishihara, Kana Sakamoto, Koji Kawamura, Masahiro Ashizawa, Kiriko Terasako-Saito, Shun-Ichi Kimura, Hideki Nakasone, Misato Kikuchi, Aki Tanihara, Rie Yamazaki, Yukie Tanaka, Junya Kanda, Junji Nishida, Kunihiko Morita, Yoshinobu Kanda. Pharmacokinetics study of once-daily intravenous busulfan in conditioning regimens for hematopoietic stem cell transplantation. Int. J. Hematol.. 2015.05; 101 (5): 497-504. ( PubMed, DOI )

  7. R Yamazaki, Y Tanaka, H Nakasone, M Sato, K Terasako-Saito, K Sakamoto, Y Akahoshi, H Nakano, T Ugai, R Yamasaki, H Wada, Y Ishihara, K Kawamura, M Ashizawa, S-I Kimura, M Kikuchi, S Kako, J Kanda, A Tanihara, J Nishida, Y Kanda. Allotype analysis to determine the origin of cytomegalovirus immunoglobulin-G after allogeneic stem cell transplantation. Transpl Infect Dis. 2014.12; 16 (6): 904-913. ( PubMed, DOI )

  8. K Terasako-Saito, H Nakasone, Y Tanaka, R Yamazaki, M Sato, K Sakamoto, Y Ishihara, K Kawamura, Y Akahoshi, J Hayakawa, H Wada, N Harada, H Nakano, K Kameda, T Ugai, R Yamasaki, M Ashizawa, S-I Kimura, M Kikuchi, A Tanihara, J Kanda, S Kako, J Nishida, Y Kanda. Persistence of recipient-derived as well as donor-derived clones of cytomegalovirus pp65-specific cytotoxic T cells long after allogeneic hematopoietic stem cell transplantation. Transpl Infect Dis. 2014.12; 16 (6): 930-940. ( PubMed, DOI )

  9. Hideki Nakasone, Kiriko Terasako-Saito, Rie Yamazaki, Miki Sato, Yukie Tanaka, Kana Sakamoto, Masakazu Kurita, Ryoko Yamasaki, Hidenori Wada, Yuko Ishihara, Koji Kawamura, Tomohito Machishima, Masahiro Ashizawa, Shun-Ichi Kimura, Misato Kikuchi, Aki Tanihara, Junya Kanda, Shinichi Kako, Junji Nishida, Shigeki Yamada, Yoshinobu Kanda. Impact of high-/middle-molecular-weight adiponectin on the synthesis and regulation of extracellular matrix in dermal fibroblasts. Exp. Hematol.. 2014.04; 42 (4): 261-273. ( PubMed, DOI )

  10. M Sato, H Nakasone, K Terasako-Saito, K Sakamoto, R Yamazaki, Y Tanaka, Y Akahoshi, H Nakano, T Ugai, H Wada, R Yamasaki, Y Ishihara, K Kawamura, M Ashizawa, S-i Kimura, M Kikuchi, A Tanihara, J Kanda, S Kako, J Nishida, Y Kanda. Prediction of infectious complications by the combination of plasma procalcitonin level and localized infection before allogeneic hematopoietic cell transplantation. Bone Marrow Transplant.. 2014.04; 49 (4): 553-560. ( PubMed, DOI )

  11. Yukie Tanaka, Rie Yamazaki, Kiriko Terasako-Saito, Hideki Nakasone, Yu Akahoshi, Hirofumi Nakano, Tomotaka Ugai, Hidenori Wada, Ryoko Yamasaki, Yuko Ishihara, Koji Kawamura, Kana Sakamoto, Masahiro Ashizawa, Miki Sato, Shun-ichi Kimura, Misato Kikuchi, Shinichi Kako, Junya Kanda, Aki Tanihara, Junji Nishida, Yoshinobu Kanda. Universal cytotoxic activity of a HTLV-1 Tax-specific T cell clone from an HLA-A*24:02⁺ patient with adult T-cell leukemia against a variety of HTLV-I-infected T-cells. Immunol. Lett.. 2014.03; 158 (1-2): 120-125. ( PubMed, DOI )

  12. H Nakasone, Y Tanaka, R Yamazaki, K Terasako, M Sato, K Sakamoto, R Yamasaki, H Wada, Y Ishihara, K Kawamura, T Machishima, M Ashizawa, S-I Kimura, M Kikuchi, A Tanihara, J Kanda, S Kako, J Nishida, Y Kanda. Single-cell T-cell receptor-β analysis of HLA-A*2402-restricted CMV- pp65-specific cytotoxic T-cells in allogeneic hematopoietic SCT. Bone Marrow Transplant.. 2014.01; 49 (1): 87-94. ( PubMed, DOI )

  13. Koji Kawamura, Misato Kikuchi, Kiriko Terasako, Hidenori Wada, Ryoko Yamasaki, Yuko Ishihara, Kana Sakamoto, Masahiro Ashizawa, Miki Sato, Tomohito Machishima, Shun-ichi Kimura, Hideki Nakasone, Shinya Okuda, Rie Yamazaki, Junya Kanda, Shinichi Kako, Yukie Tanaka, Aki Tanihara, Junji Nishida, Yoshinobu Kanda. Comparison of the efficacy of peripheral blood stem cell mobilization using G-CSF alone from healthy donors and patients with hematologic malignancies. Transfus. Apher. Sci.. 2013.10; 49 (2): 334-340. ( PubMed, DOI )

  14. M Sato, H Nakasone, H Wada, R Yamasaki, Y Ishihara, K Sakamoto, K Kawamura, M Ashizawa, T Machishima, K Terasako, S-I Kimura, M Kikuchi, A Tanihara, R Yamazaki, Y Tanaka, J Kanda, S Kako, J Nishida, Y Kanda. Prediction of infectious events by the high-sensitivity C-reactive protein level before autologous hematopoietic cell transplantation for lymphoma and multiple myeloma. Transpl Infect Dis. 2013.08; 15 (4): E169-E171. ( PubMed, DOI )

  15. Rie Yamazaki, Hideki Nakasone, Yukie Tanaka, Miki Sato, Kiriko Terasako, Hidenori Wada, Yuko Ishihara, Koji Kawamura, Kana Sakamoto, Masahiro Ashizawa, Tomohito Machishima, Shun-Ichi Kimura, Misato Kikuchi, Shinya Okuda, Shinichi Kako, Junya Kanda, Aki Tanihara, Junji Nishida, Yoshinobu Kanda. Allotype analysis to distinguish the origin of varicella-zoster virus immunoglobulin G after allogeneic stem cell transplantation. Biol. Blood Marrow Transplant.. 2013.07; 19 (7): 1013-1020. ( PubMed, DOI )

  16. M Sato, H Nakasone, K Oshima, Y Ishihara, H Wada, K Sakamoto, K Kawamura, M Ashizawa, T Machishima, K Terasako, S Kimura, M Kikuchi, S Okuda, A Tanihara, R Yamazaki, Y Tanaka, J Kanda, S Kako, J Nishida, Y Kanda. Prediction of transplant-related complications by C-reactive protein levels before hematopoietic SCT. Bone Marrow Transplant.. 2013.05; 48 (5): 698-702. ( PubMed, DOI )

  17. Yukie Tanaka, Hideki Nakasone, Rie Yamazaki, Hidenori Wada, Yuko Ishihara, Koji Kawamura, Kana Sakamoto, Masahiro Ashizawa, Tomohito Machishima, Miki Sato, Kiriko Terasako, Shun-ichi Kimura, Misato Kikuchi, Shinya Okuda, Shinichi Kako, Junya Kanda, Aki Tanihara, Junji Nishida, Yoshinobu Kanda. Long-term persistence of limited HTLV-I Tax-specific cytotoxic T cell clones in a patient with adult T cell leukemia/lymphoma after allogeneic stem cell transplantation. J. Clin. Immunol.. 2012.12; 32 (6): 1340-1352. ( PubMed, DOI )

  18. S-I Kimura, H Wada, K Sakamoto, M Ashizawa, M Sato, K Terasako, H Nakasone, M Kikuchi, S Okuda, S Kako, R Yamazaki, K Oshima, Y Tanaka, A Tanihara, J Nishida, Y Kanda. L-index as a novel index to evaluate both the intensity and duration of lymphopenia after allogeneic hematopoietic stem cell transplantation. Transpl Infect Dis. 2012.08; 14 (4): 364-373. ( PubMed, DOI )

  19. Soyoko Morimoto, Yoshihiro Oka, Akihiro Tsuboi, Yukie Tanaka, Fumihiro Fujiki, Hiroko Nakajima, Naoki Hosen, Sumiyuki Nishida, Jun Nakata, Yoshiki Nakae, Motohiko Maruno, Akira Myoui, Takayuki Enomoto, Shuichi Izumoto, Mitsugu Sekimoto, Naoki Kagawa, Naoya Hashimoto, Toshiki Yoshimine, Yusuke Oji, Atsushi Kumanogoh, Haruo Sugiyama. Biased usage of T cell receptor β-chain variable region genes of Wilms' tumor gene (WT1)-specific CD8+ T cells in patients with solid tumors and healthy donors. Cancer Sci.. 2012.03; 103 (3): 408-414. ( PubMed, DOI )

  20. Rie Yamazaki, Hideki Nakasone, Hidenori Wada, Kana Sakamoto, Masahiro Ashizawa, Miki Sato, Kiriko Terasako, Misato Kikuchi, Shun-Ichi Kimura, Shinya Okuda, Shinichi Kako, Yukie Tanaka, Aki Tanihara, Kumi Oshima, Junji Nishida, Yoshinobu Kanda. Recurrence of monoclonal gammopathy associated with donor-derived myelodysplastic syndrome after cord blood stem cell transplantation. Exp. Hematol.. 2011.12; 39 (12): 1119-1123. ( PubMed, DOI )

  21. Toshiaki Yoshikawa, Munehide Nakatsugawa, Shiro Suzuki, Hirofumi Shirakawa, Daisuke Nobuoka, Noriko Sakemura, Yutaka Motomura, Yukie Tanaka, Shin-Ichi Hayashi, Tetsuya Nakatsura. HLA-A2-restricted glypican-3 peptide-specific CTL clones induced by peptide vaccine show high avidity and antigen-specific killing activity against tumor cells. Cancer Sci.. 2011.05; 102 (5): 918-925. ( PubMed, DOI )

  22. Hideki Nakasone, Phan Nguyen Thanh Binh, Rie Yamazaki, Yukie Tanaka, Kana Sakamoto, Masahiro Ashizawa, Miki Sato, Kiriko Terasako, Shun-ichi Kimura, Misato Kikuchi, Shinichi Kako, Shinya Okuda, Kumi Oshima, Aki Tanihara, Junji Nishida, Yasunori Abe, Yoshinobu Kanda. Association between serum high-molecular-weight adiponectin level and the severity of chronic graft-versus-host disease in allogeneic stem cell transplantation recipients. Blood. 2011.03; 117 (12): 3469-3472. ( PubMed, DOI )

  23. Nakasone H., Binh P. N. T, Yamazaki R., Tanaka Y., Sakamoto K., Ashizawa M., Sato M., Terasako K., Kimura S. - I, Kikuchi M., Kako S., Okuda S., Oshima K., Tanihara A., Nishida J., Abe Y., Kanda Y.. ASSOCIATION BETWEEN SERUM HIGH-MOLECULAR-WEIGHT ADIPONECTIN LEVEL AND THE SEVERITY OF CHRONIC GRAFT-VERSUS-HOST DISEASE IN ALLOGENEIC STEM CELL TRANSPLANTATION RECIPIENTS BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. 2011.02; 17 (2): S338.

  24. Kimura Shun-ichi, Oshima Kumi, Sato Ken, Sato Miki, Terasako Kiriko, Nakasone Hideki, Kikuchi Misato, Okuda Shinya, Kako Shinichi, Yamazaki Rie, Tanaka Yukie, Tanihara Aki, Nishida Junji, Kanda Yoshinobu. Retrospective Evaluation of the Area Over the Neutrophil Curve Index to Predict Early Infection in Hematopoietic Stem Cell Transplantation Recipients BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. 2010.10; 16 (10): 1355-1361. ( DOI )

  25. Yukie Tanaka, Hideki Nakasone, Rie Yamazaki, Ken Sato, Miki Sato, Kiriko Terasako, Shun-ichi Kimura, Shinya Okuda, Shinichi Kako, Kumi Oshima, Aki Tanihara, Junji Nishida, Toshiaki Yoshikawa, Tetsuya Nakatsura, Haruo Sugiyama, Yoshinobu Kanda. Single-cell analysis of T-cell receptor repertoire of HTLV-1 Tax-specific cytotoxic T cells in allogeneic transplant recipients with adult T-cell leukemia/lymphoma. Cancer Res.. 2010.08; 70 (15): 6181-6192. ( PubMed, DOI )

  26. Kiriko Terasako, Ken Sato, Miki Sato, Shun-ichi Kimura, Hideki Nakasone, Shinya Okuda, Shinichi Kako, Yukie Tanaka, Rie Yamazaki, Kumi Oshima, Aki Tanihara, Takakazu Higuchi, Junji Nishida, Yoshinobu Kanda. The effect of different ATG preparations on immune recovery after allogeneic hematopoietic stem cell transplantation for severe aplastic anemia. Hematology. 2010.06; 15 (3): 165-169. ( PubMed, DOI )

  27. Fujiki Fumihiro, Oka Yoshihiro, Kawakatsu Mai, Tsuboi Akihiro, Tanaka-Harada Yukie, Hosen Naoki, Nishida Sumiyuki, Shirakata Toshiaki, Nakajima Hiroko, Tatsumi Naoya, Hashimoto Naoya, Taguchi Tetsuya, Ueda Satsuki, Nonomura Norio, Takeda Yutaka, Ito Toshinori, Myoui Akira, Izumoto Shuichi, Maruno Motohiko, Yoshimine Toshiki, Noguchi Shinzaburo, Okuyama Akihiko, Kawase Ichiro, Oji Yusuke, Sugiyama Haruo. A Clear Correlation between WT1-specific Th Response and Clinical Response in WT1 CTL Epitope Vaccination ANTICANCER RESEARCH. 2010.06; 30 (6): 2247-2254.

  28. Kimura S., Oshima K., Okuda S., Sato K., Sato M., Terasako K., Nakasone H., Kako S., Yamazaki R., Tanaka Y., Tanihara A., Higuchi T., Nishida J., Kanda Y.. Pharmacokinetics of CsA during the switch from continuous intravenous infusion to oral administration after allogeneic hematopoietic stem cell transplantation BONE MARROW TRANSPLANTATION. 2010.06; 45 (6): 1088-1094. ( DOI )

  29. Ayako Murao, Yoshihiro Oka, Akihiro Tsuboi, Olga A Elisseeva, Yukie Tanaka-Harada, Fumihiro Fujiki, Hiroko Nakajima, Sumiyuki Nishida, Naoki Hosen, Toshiaki Shirakata, Nobuyuki Hashimoto, Akira Myoui, Takafumi Ueda, Yoshito Takeda, Tadashi Osaki, Takayuki Enomoto, Hideki Yoshikawa, Tadashi Kimura, Yusuke Oji, Ichiro Kawase, Haruo Sugiyama. High frequencies of less differentiated and more proliferative WT1-specific CD8+ T cells in bone marrow in tumor-bearing patients: an important role of bone marrow as a secondary lymphoid organ. Cancer Sci.. 2010.04; 101 (4): 848-854. ( PubMed, DOI )

  30. Yukie Tanaka-Harada, Manabu Kawakami, Yoshihiro Oka, Akihiro Tsuboi, Takamasa Katagiri, Olga A Elisseeva, Sumiyuki Nishida, Toshiaki Shirakata, Naoki Hosen, Fumihiro Fujiki, Ayako Murao, Hiroko Nakajima, Yusuke Oji, Yoshinobu Kanda, Ichiro Kawase, Haruo Sugiyama. Biased usage of BV gene families of T-cell receptors of WT1 (Wilms' tumor gene)-specific CD8+ T cells in patients with myeloid malignancies. Cancer Sci.. 2010.03; 101 (3): 594-600. ( PubMed, DOI )

  31. Nakasone Hideki, Kako Shinichi, Endo Hiroshi, Ito Ayumu, Sato Miki, Terasako Kiriko, Okuda Shinya, Tanaka Yukie, Yamazaki Rie, Oshima Kumi, Tanihara Aki, Kida Michiko, Higuchi Takakazu, Izutsu Koji, Nishida Junji, Urabe Akio, Usuki Kensuke, Kanda Yoshinobu. Diabetes mellitus is associated with high early-mortality and poor prognosis in patients with autoimmune hemolytic anemia HEMATOLOGY. 2009.12; 14 (6): 361-365. ( DOI )

  32. Shinichi Kako, Kumi Oshima, Miki Sato, Kiriko Terasako, Shinya Okuda, Hideki Nakasone, Rie Yamazaki, Yukie Tanaka, Aki Tanihara, Yutaka Kawamura, Hirokazu Kiyosaki, Takakazu Higuchi, Junji Nishida, Fumio Konishi, Yoshinobu Kanda. Clinical outcome in patients with small-intestinal non-Hodgkin lymphoma. Leuk. Lymphoma. 2009.10; 50 (10): 1618-1624. ( PubMed, DOI )

  33. Oshima Kumi, Sato Miki, Okuda Shinya, Terasako Kiriko, Nakasone Hideki, Kako Shinichi, Yamazaki Rie, Tanaka Yukie, Tanihara Aki, Higuchi Takakazu, Nishida Junji, Nakamura Ikuo, Yoshida Yukio, Kanda Yoshinobu. Reverse seroconversion of hepatitis B virus after allogeneic hematopoietic stem cell transplantation in the absence of chronic graft-versus-host disease HEMATOLOGY. 2009.04; 14 (2): 73-75. ( DOI )

  34. Shinya Okuda, Kiriko Terasako, Kumi Oshima, Miki Sato, Hideki Nakasone, Shinichi Kako, Rie Yamazaki, Yukie Tanaka, Aki Tanihara, Takakazu Higuchi, Junji Nishida, Yoshinobu Kanda. Fludarabine, cyclophosphamide, anti-thymocyteglobulin, and low-dose total body irradiation conditioning enables 1-HLA-locus-mismatched hematopoietic stem cell transplantation for very severe aplastic anemia without affecting ovarian function. Am. J. Hematol.. 2009.03; 84 (3): 167-169. ( PubMed, DOI )

  35. Fujiki Fumihiro, Oka Yoshihiro, Kawakatsu Mai, Tsuboi Akihiro, Nakajima Hiroko, Elisseeva Olga A., Harada Yukie, Li Zheyu, Tatsumi Naoko, Kamino Eriko, Shirakata Toshiaki, Nishida Sumiyuki, Taniguchi Yuki, Kawase Ichiro, Oji Yusuke, Sugiyama Haruo. A WT1 protein-derived, naturally processed 16-mer peptide, WT1(332), is a promiscuous helper peptide for induction of WT1-specific Th1-type CD4(+) T cells MICROBIOLOGY AND IMMUNOLOGY. 2008.12; 52 (12): 591-600. ( DOI )

  36. Li Zheyu, Oka Yoshihiro, Tsuboi Akihiro, Fujiki Fumihiro, Harada Yukie, Nakajima Hiroko, Masuda Tomoki, Fukuda Yoko, Kawakatsu Mai, Morimoto Soyoko, Katagiri Takamasa, Tatsumi Naoya, Hosen Naoki, Shirakata Toshiaki, Nishida Sumiyuki, Kawakami Yutaka, Udaka Keiko, Kawase Ichiro, Oji Yusuke, Sugiyama Haruo. Identification of a WT1 protein-derived peptide, WT1(187), as a HLA-A*0206-restricted, WT1-specific CTL epitope MICROBIOLOGY AND IMMUNOLOGY. 2008.11; 52 (11): 551-558. ( DOI )

  37. Kawakami Manabu, Oka Yoshihiro, Tsuboi Akihiro, Harada Yukie, Elisseeva Olga A., Furukawa Yoshio, Tsukaguchi Machiko, Shirakata Toshiaki, Nishida Sumiyuki, Nakajima Hiroko, Morita Satoshi, Sakamoto Junichi, Kawase Ichiro, Oji Yusuke, Sugiyama Haruo. Clinical and immunologic responses to very low-dose vaccination with WT1 peptide (5 mu g/body) in a patient with chronic myelomonocytic leukemia INTERNATIONAL JOURNAL OF HEMATOLOGY. 2007.06; 85 (5): 426-429. ( DOI )

  38. Fujiki Fumihiro, Oka Yoshihiro, Tsuboi Akihiro, Kawakami Manabu, Kawakatsu Mai, Nakajima Hiroko, Elisseeva Olga A., Harada Yukie, Ito Ken, Li Zheyu, Tatsumi Naoya, Sakaguchi Nao, Fujioka Tatsuya, Masuda Tomoki, Yasukawa Masaki, Udaka Keiko, Kawase Ichiro, Oji Yusuke, Sugiyama Haruo. Identification and characterization of a WT1 (Wilms tumor gene) protein-derived HLA-DRB1*0405-restricted 16-mer helper peptide that promotes the induction and activation of WT1-specific cytotoxic T lymphocytes JOURNAL OF IMMUNOTHERAPY. 2007.04; 30 (3): 282-293.

  39. Nishida S, Hosen N, Shirakata T, Kanato K, Yanagihara M, Nakatsuka S, Hoshida Y, Nakazawa T, Harada Y, Tatsumi N, Tsuboi A, Kawakami M, Oka Y, Oji Y, Aozasa K, Kawase I, Sugiyama H. AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1. BLOOD. 2006.04; 107 (8): 3303-3312. ( DOI )

  40. Yukie Harada, Osamu Imataki, Yuji Heike, Hiroyuki Kawai, Akihiro Shimosaka, Shin-ichiro Mori, Masahiro Kami, Ryuji Tanosaki, Yoshinori Ikarashi, Akira Iizuka, Mitsuji Yoshida, Hiro Wakasugi, Shigeru Saito, Yoichi Takaue, Masao Takei, Tadao Kakizoe. Expansion of alpha-galactosylceramide-stimulated Valpha24+ NKT cells cultured in the absence of animal materials. J. Immunother.. 2005.07; 28 (4): 314-321. ( PubMed )

  41. Shin-ichi Hori, Yuji Heike, Masao Takei, Midori Maruyama, Yoshiko Inoue, Je-Jung Lee, Hyeoung-Joon Kim, Yukie Harada, Hiroyuki Kawai, Akihiro Shimosaka, Masahiro Kami, M D Ryuji Tanosaki, Hiro Wakasugi, Shigeru Saito, Yoichi Takaue, Tadao Kakizoe. Freeze-thawing procedures have no influence on the phenotypic and functional development of dendritic cells generated from peripheral blood CD14+ monocytes. J. Immunother.. 2004.01; 27 (1): 27-35. ( PubMed )

  42. Rumiko Asada-Mikami, Yuji Heike, Yukie Harada, Sachiyo Kanai, Yoshinori Ikarashi, Kazunori Kato, Kazuo Shirakawa, Yoichi Takaue, Tatsuo Abe, Hiro Wakasugi. Increased expansion of V alpha 24+ T cells derived from G-CSF-mobilized peripheral blood stem cells as compared to peripheral blood mononuclear cells following alpha-galactosylceramide stimulation. Cancer Sci.. 2003.04; 94 (4): 383-388. ( PubMed )

  43. Je-Jung Lee, Masao Takei, Shinichi Hori, Yoshiko Inoue, Yukie Harada, Ryuji Tanosaki, Yoshinobu Kanda, Masayuki Kami, Atsushi Makimoto, Shin Mineishi, Hiroyuki Kawai, Akihiro Shimosaka, Yuji Heike, Yoshinori Ikarashi, Hiro Wakasugi, Yoichi Takaue, Tai-Ju Hwang, Hyeoung-Joon Kim, Tadao Kakizoe. The role of PGE(2) in the differentiation of dendritic cells: how do dendritic cells influence T-cell polarization and chemokine receptor expression? Stem Cells. 2002.09; 20 (5): 448-459. ( PubMed, DOI )

  44. Y Inoue, Y Takaue, M Takei, K Kato, S Kanai, Y Harada, K Tobisu, M Noguchi, T Kakizoe, K Itoh, H Wakasugi. Induction of tumor specific cytotoxic T lymphocytes in prostate cancer using prostatic acid phosphatase derived HLA-A2402 binding peptide. J. Urol.. 2001.10; 166 (4): 1508-1513. ( PubMed )

  45. Tani-Sassa Chihiro, Iwasaki Yumi, Ichimura Naoya, Nagano Katsutoshi, Takatsuki Yuna, Yuasa Sonoka, Takahashi Yuta, Nakajima Jun, Sonobe Kazunari, Nukui Yoko, Takeuchi Hiroaki, Tanimoto Kousuke, Tanaka Yukie, Kimura Akinori, Tohda Shuji. Viral loads and profile of the patients infected with SARS-CoV-2 Delta, Alpha, or R.1 variants in Tokyo JOURNAL OF MEDICAL VIROLOGY. 2021.12; ( PubMed, DOI )

  46. Yukie Tanaka, Yoshinobu Kanda. [Development of Tax-redirected T-cell immunotherapy using TCR gene transduction in patients with ATL]. Rinsho Ketsueki. 2015.07; 56 (7): 815-824. ( PubMed, DOI )

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講演・口頭発表等 【 表示 / 非表示

  1. Akira Nishimura, Kazuaki Yokoyama, Takuya Naruto, Hiroto Nakazono, Chika Yamagishi, Yukie Tanaka, Tomohiro Morio 他. Comprehensive Genetic Analysis Revealed Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia As a Novel Distinctive Leukemia Entity. The 62nd ASH Annual Meeting 2020.12.06

  2. Kawamura K, Tanaka Y, Kanda Y, et al.. Development of Tax-redirected T-cell immunotherapy for adult T cell leukemia. 22nd Congress of European Hematology Association 2017.06.22 Madrid

  3. Tanaka Y, Fujita Y, Kawana-Tachikawa A, Leen AM, Heslop HE, Morio T, Takahashi S . Generation of Multivirus-specific T-cells by a Single Stimulation of PBMCs with a Peptide Mixture Utilizing Serum Free Medium. 2015.10.29 Okinawa

  4. Tanaka Y. Investigation of redirected T-cell immunotherapy against Tax. The 76th Annual Meeting of the Japanese Society of Hematology 2014.10.31 Osaka

  5. 田中ゆきえ、小林誠一郎、佐藤知雄、山野嘉久、神田善伸、内丸薫、森尾友宏. HTLV-I感染により誘導されるウイルス抗原特異的幹細胞様メモリーT細胞の解析. 第12回日本血液疾患免疫療法学会学術集会 2020.09.12 大阪

  6. 藤田由利子、立川(川名)愛、田中ゆきえ、Helen E Heslop、加藤節史、岡本圭祐、河野ゆり、辻彩子、草野純、柳町昌克、森尾友宏、高橋聡. 造血細胞移植後難治性ウイルス感染症に対するHLA半合致以上血縁ドナー由来複数ウイルス特異的T細胞療法. 第41回日本造血細胞移植学会総会 2019.03.07

  7. 石原優子、田中ゆきえ、内丸薫、神田善伸、他. HTLV-1無症候キャリア及びATLにおけるTax-CTLのレパトア解析. 第78回日本血液学会 2016.10.13 横浜

  8. 田中ゆきえ. Tax特異的TCR遺伝子導入細胞によるATLに対する細胞免疫療法の開発. 第20回 血液科学セミナー 2014.11.08 東京

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受賞学術賞 【 表示 / 非表示

  • 自治医科大学医学部優秀論文賞,自治医科大学,2011年04月

その他業績 【 表示 / 非表示

  • 「北米地域で確認されているオミクロン系統株の本邦市中流行、および市中に長期間存続しているデルタ系統株への感染事例を確認」~医科歯科大 新型コロナウイルス全ゲノム解析プロジェクト 第10報~ ,2022年01月

  • 「N501S変異を有する新たなデルタ株(B.1.617.2系統)のブレイクスルー感染事例を確認」~医科歯科大 新型コロナウイルス全ゲノム解析プロジェクト 第9報~,2021年09月

  • 「N501S 変異を有する新たなデルタ株(B.1.617.2 系統)の市中感染事例(国内第1例目)を確認」~医科歯科大 新型コロナウイルス全ゲノム解析プロジェクト 第8報~,2021年08月

  • 「デルタ株(B.1.617.2系統)およびデルタ亜系統株(AY.3系統)の市中感染共存事例を確認」~医科歯科大 新型コロナウイルス全ゲノム解析プロジェクト 第7報~,2021年08月

  • 「インド型SARS-CoV-2系統株(B.1.617系統)の新たな市中感染事例を確認」~医科歯科大 新型コロナウイルス全ゲノム解析プロジェクト 第6報~,2021年05月

  • 「免疫逃避型(E484K変異)系統株と英国型(N501Y変異)系統株の市中感染共存事例を確認」~医科歯科大 新型コロナウイルス全ゲノム解析プロジェクト 第5報~,2021年04月

  • 「免疫逃避型(E484K 変異)変異株を含む多様な市中流行株の感染事例を確認」~医科歯科大 新型コロナウイルス全ゲノム解析プロジェクト 第4報~,2021年04月

  • 「市中感染事例における海外系統株の増加を確認」~医科歯科大 新型コロナウイルス全ゲノム解析プロジェクト 第3報~,2021年03月

  • 「免疫逃避型変異(E484K 変異)を有する海外(カナダ)系統株の新たな市中感染事例を確認」~医科歯科大 新型コロナウイルス全ゲノム解析プロジェクト 第2報~,2021年02月

  • 「英国SARS-CoV-2系統株の新たな市中感染事例を確認」―市中流行株の変遷に影響をおよぼす可能性―,2021年01月

  • 日本血液学会平成31年度研究助成,2019年09月

    HTLV-I Tax ステムセルメモリー T 細胞 の治療応用に向けた 基盤研究 (研究代表者)

  • 2019年度 武田科学振興財団 医学系研究助成(がん領域(臨床)),2019年08月

    成人T細胞白血病の発症阻止におけるステムセルメモリーT細胞の役割解明と新規治療法の開発 (研究代表者)

  • 日本血液学会平成30年度研究助成,2018年10月

    HTLV-I Tax特異的ステムセルメモリーT細胞の解析とその治療応用に向けた研究 (研究代表者)

  • 文部科学省 科学研究費補助金 (基盤研究C),2018年04月

    「ATL発症阻止における幹細胞様メモリーT細胞の役割の解明と治療応用」(18K07292) (研究代表者)

  • 日本血液学会平成29年度研究助成,2017年11月

    「共有TCRモチーフ型」HTLV-I Tax特異的CD8T細胞のHTLV-I関連疾患における免疫学的役割の解明 (研究代表者)

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