論文・総説 - 金山　剛士

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  1. Akiyama M, Kanayama M, Umezawa Y, Nagao T, Izumi Y, Yamamoto M, Ohteki T. An early regulatory mechanism of hyperinflammation by restricting monocyte contribution. Frontiers in immunology. 2024.07; 15 1398153. ( PubMed, DOI )

  2. Masashi Kanayama, Yuta Izumi, Megumi Akiyama, Toyoki Hayashi, Koji Atarashi, Axel Roers, Taku Sato, Toshiaki Ohteki. Myeloid-like B cells boost emergency myelopoiesis through IL-10 production during infection JOURNAL OF EXPERIMENTAL MEDICINE. 2023.01; 220 (4): ( PubMed, DOI )

  3. Chikuma S, Yamanaka S, Nakagawa S, Ueda MT, Hayabuchi H, Tokifuji Y, Kanayama M, Okamura T, Arase H, Yoshimura A. TRIM28 Expression on Dendritic Cells Prevents Excessive T Cell Priming by Silencing Endogenous Retrovirus. Journal of immunology (Baltimore, Md. : 1950). 2021.02; 206 (7): 1528-1539. ( PubMed, DOI )

  4. Izumi Y, Kanayama M, Shen Z, Kai M, Kawamura S, Akiyama M, Yamamoto M, Nagao T, Okada K, Kawamata N, Toyota S, Ohteki T. An Antibody-Drug Conjugate That Selectively Targets Human Monocyte Progenitors for Anti-Cancer Therapy. Frontiers in immunology. 2021.02; 12 618081. ( PubMed, DOI )

  5. Liang J, Zhang JJ, Huang HI, Kanayama M, Youssef N, Jin YJ, Reyes EY, Abram CL, Yang S, Lowell CA, Wang D, Shao L, Shinohara ML, Zhang JY, Hammer GE. The ubiquitin-modifying enzyme A20 terminates C-type lectin receptor signals and is a suppressor of host defense against systemic fungal infection. Infection and immunity. 2020.06; 88 (9): ( PubMed, DOI )

  6. Kanayama M, Izumi Y, Yamauchi Y, Kuroda S, Shin T, Ishikawa S, Sato T, Kajita M, Ohteki T. CD86-based analysis enables observation of bona fide hematopoietic responses. Blood. 2020.05; ( PubMed, DOI )

  7. 泉 湧太, 金山 剛士, 秋山 めぐみ, 甲斐 正之, 沈 鐘楚子, 川又 紀彦, 樗木 俊聡. Targeting monocyte lineage-restricted antigen as a novel therapeutic strategy for monocytic leukemia(和訳中) 日本病理学会会誌. 2020.03; 109 (1): 304. ( 医中誌 )

  8. Kanayama Masashi, Izumi Yuta, Ohteki Toshiaki. Hematopoiesis and Immune Environment　Analysis with an alternative marker for Sca-1 revealed bona fide hematopoietic responses during infection(和訳中) 日本免疫学会総会・学術集会記録. 2019.11; 48 (Proceedings): 1-H. ( 医中誌 )

  9. Kanayama Masashi, Xu Shengjie, Danzaki Keiko, Gibson Jason R., Inoue Makoto, Gregory Simon G., Shinohara Mari L.. Skewing the population balance between lymphoid and myeloid cells by osteopontin isoforms CYTOKINE. 2017.12; 100 161.

  10. Kanayama Masashi, Xu Shengjie, Gibson Jason R, Inoue Makoto, Gregory Simon G, Shinohara Mari L. Hematopoiesis and immune environments Balancing population sizes of myeloid and lymphoid cells by osteopontin isoforms(和訳中) 日本免疫学会総会・学術集会記録. 2017.12; 46 (Proceedings): 1-G. ( 医中誌 )

  11. Masashi Kanayama, Shengjie Xu, Keiko Danzaki, Jason R Gibson, Makoto Inoue, Simon G Gregory, Mari L Shinohara. Skewing of the population balance of lymphoid and myeloid cells by secreted and intracellular osteopontin. Nature Immunology. 2017.07; ( PubMed, DOI )

  12. Keiko Danzaki, Masashi Kanayama, Oscar Alcazar, Mari L Shinohara. Osteopontin has a protective role in prostate tumor development in mice. European journal of immunology. 2016.11; 46 (11): 2669-2678. ( PubMed, DOI )

  13. Masashi Kanayama, Keiko Danzaki, You-Wen He, Mari L Shinohara. Lung inflammation stalls Th17-cell migration en route to the central nervous system during the development of experimental autoimmune encephalomyelitis. Int. Immunol.. 2016.09; 28 (9): 463-469. ( PubMed, DOI )

  14. Masashi Kanayama, Mari L Shinohara. Roles of Autophagy and Autophagy-Related Proteins in Antifungal Immunity. Front Immunol. 2016.02; 7 47. ( PubMed, DOI )

  15. Tsutomu Endo, Koyu Ito, Junko Morimoto, Masashi Kanayama, Daichi Ota, Masahiro Ikesue, Shigeyuki Kon, Daisuke Takahashi, Tomohiro Onodera, Norimasa Iwasaki, Toshimitsu Uede. Syndecan 4 Regulation of the Development of Autoimmune Arthritis in Mice by Modulating B Cell Migration and Germinal Center Formation. Arthritis & rheumatology (Hoboken, N.J.). 2015.09; 67 (9): 2512-2522. ( PubMed, DOI )

  16. Masashi Kanayama, You-Wen He, Mari L Shinohara. The lung is protected from spontaneous inflammation by autophagy in myeloid cells. J. Immunol.. 2015.06; 194 (11): 5465-5471. ( PubMed, DOI )

  17. Masashi Kanayama, Makoto Inoue, Keiko Danzaki, Gianna Hammer, You-Wen He, Mari L Shinohara. Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity. Nature Communications. 2015.01; 6 5779. ( PubMed, DOI )

  18. Daichi Ota, Masashi Kanayama, Yutaka Matsui, Koyu Ito, Naoyoshi Maeda, Goro Kutomi, Koichi Hirata, Toshihiko Torigoe, Noriyuki Sato, Akinori Takaoka, Ann F Chambers, Junko Morimoto, Toshimitsu Uede. Tumor-α9β1 integrin-mediated signaling induces breast cancer growth and lymphatic metastasis via the recruitment of cancer-associated fibroblasts. J. Mol. Med.. 2014.12; 92 (12): 1271-1281. ( PubMed, DOI )

  19. Shigeyuki Kon, Yosuke Nakayama, Naoki Matsumoto, Koyu Ito, Masashi Kanayama, Chiemi Kimura, Hitomi Kouro, Dai Ashitomi, Tadashi Matsuda, Toshimitsu Uede. A novel cryptic binding motif, LRSKSRSFQVSDEQY, in the C-terminal fragment of MMP-3/7-cleaved osteopontin as a novel ligand for α9β1 integrin is involved in the anti-type II collagen antibody-induced arthritis. PLoS ONE. 2014.12; 9 (12): e116210. ( PubMed, DOI )

  20. Tsuyoshi Asano, Norimasa Iwasaki, Shigeyuki Kon, Masashi Kanayama, Junko Morimoto, Akio Minami, Toshimitsu Uede. α9β1 integrin acts as a critical intrinsic regulator of human rheumatoid arthritis. Rheumatology (Oxford). 2014.03; 53 (3): 415-424. ( PubMed, DOI )

  21. Keiko Danzaki, Yutaka Matsui, Masahiro Ikesue, Daichi Ohta, Koyu Ito, Masashi Kanayama, Daisuke Kurotaki, Junko Morimoto, Yoichiro Iwakura, Hideo Yagita, Hiroyuki Tsutsui, Toshimitsu Uede. Interleukin-17A deficiency accelerates unstable atherosclerotic plaque formation in apolipoprotein E-deficient mice. Arterioscler. Thromb. Vasc. Biol.. 2012.02; 32 (2): 273-280. ( PubMed, DOI )

  22. Yukinori Tsukuda, Norimasa Iwasaki, Naoki Seito, Masashi Kanayama, Naoki Fujitani, Yasuro Shinohara, Yasuhiko Kasahara, Tomohiro Onodera, Koji Suzuki, Tsuyoshi Asano, Akio Minami, Tadashi Yamashita. Ganglioside GM3 has an essential role in the pathogenesis and progression of rheumatoid arthritis. PLoS ONE. 2012.01; 7 (6): e40136. ( PubMed, DOI )

  23. Masashi Kanayama, Junko Morimoto, Yutaka Matsui, Masahiro Ikesue, Keiko Danzaki, Daisuke Kurotaki, Koyu Ito, Toshimichi Yoshida, Toshimitsu Uede. α9β1 integrin-mediated signaling serves as an intrinsic regulator of pathogenic Th17 cell generation. J. Immunol.. 2011.12; 187 (11): 5851-5864. ( PubMed, DOI )

  24. Daisuke Kurotaki, Shigeyuki Kon, Kyeonghwa Bae, Koyu Ito, Yutaka Matsui, Yosuke Nakayama, Masashi Kanayama, Chiemi Kimura, Yoshinori Narita, Takashi Nishimura, Kazuya Iwabuchi, Matthias Mack, Nico van Rooijen, Shimon Sakaguchi, Toshimitsu Uede, Junko Morimoto. CSF-1-dependent red pulp macrophages regulate CD4 T cell responses. J. Immunol.. 2011.02; 186 (4): 2229-2237. ( PubMed, DOI )

  25. Masashi Kanayama, Daisuke Kurotaki, Junko Morimoto, Tsuyoshi Asano, Yutaka Matsui, Yosuke Nakayama, Yoshinari Saito, Koyu Ito, Chiemi Kimura, Norimasa Iwasaki, Koji Suzuki, Tanenobu Harada, Hong Mei Li, Jun Uehara, Tadaaki Miyazaki, Akio Minami, Shigeyuki Kon, Toshimitsu Uede. Alpha9 integrin and its ligands constitute critical joint microenvironments for development of autoimmune arthritis. J. Immunol.. 2009.06; 182 (12): 8015-8025. ( PubMed, DOI )

  26. Koyu Ito, Shigeyuki Kon, Yosuke Nakayama, Daisuke Kurotaki, Yoshinari Saito, Masashi Kanayama, Chiemi Kimura, Hongyan Diao, Junko Morimoto, Yutaka Matsui, Toshimitsu Uede. The differential amino acid requirement within osteopontin in alpha4 and alpha9 integrin-mediated cell binding and migration. Matrix Biol.. 2009.01; 28 (1): 11-19. ( PubMed, DOI )

  27. Yoshinari Saito, Shigeyuki Kon, Yukio Fujiwara, Yosuke Nakayama, Daisuke Kurotaki, Naoki Fukuda, Chiemi Kimura, Masashi Kanayama, Koyu Ito, Hongyan Diao, Yutaka Matsui, Yasuo Komatsu, Eiko Ohtsuka, Toshimitsu Uede. Osteopontin small interfering RNA protects mice from fulminant hepatitis. Hum. Gene Ther.. 2007.12; 18 (12): 1205-1214. ( PubMed, DOI )

  28. 金山 剛士, 樗木 俊聡. 【造血研究の最前線】緊急時造血応答におけるミエロイド様B細胞の役割 臨床免疫・アレルギー科. 2024.10; 82 (4): 339-345. ( 医中誌 )

  29. 金山剛士, 樗木俊聡. 感染時に出現する調節性B細胞 実験医学増刊号　ヒト疾患と免疫細胞サブセット. 2024.07; 42 (12):

  30. 泉 湧太, 金山 剛士, 樗木 俊聡. 【シン・マクロファージ　あらゆる疾患を制御する機能的多様性】(第2章)病気とマクロファージの多様性を知る14の方法　マクロファージ分化経路とその治療標的としての可能性 実験医学. 2022.03; 40 (5): 704-709. ( 医中誌 )

  31. 泉　湧太, 金山　剛士, 樗木　俊聡. 単球・マクロファージの分化経路 血液内科. 2021.07; 83 (1): 1-7.

  32. 金山 剛士, 樗木 俊聡. 【免疫系の暴走　サイトカインストーム　多様な疾患で生じる全身性の炎症反応その共通機構から病態を理解する】高サイトカイン血症と単球・マクロファージ 実験医学. 2021.03; 39 (4): 512-516. ( 医中誌 )

  33. 金山 剛士. 免疫老化における胸腺マクロファージの機能解析 上原記念生命科学財団研究報告集. 2019.12; 33 1-4. ( 医中誌 )

  34. 金山剛士, 篠原眞理. 分泌型および細胞内型のオステオポンチンによるミエロイド系細胞とリンパ球系細胞とのバランスの制御 臨床免疫・アレルギー科　. 2018.03; 63 (3): 219-224.

  35. 金山 剛士, 篠原 眞理. 【リンパ球の分化と機能制御】 分泌型および細胞内型のオステオポンチンによるミエロイド系細胞とリンパ球系細胞のバランス制御 臨床免疫・アレルギー科. 2018.03; 69 (3): 219-224. ( 医中誌 )

  36. 遠藤 努, 伊藤 甲雄, 森本 純子, 金山 剛士, 太田 大地, 池末 昌弘, 今 重之, 小野寺 智洋, 高橋 大介, 岩崎 倫政, 上出 利光. Syndecan-4 regulates development of autoimmune arthritis by modulating B cell migration and germinal center formation　自己免疫性関節炎におけるシンデカン-4の機能解析 北海道整形災害外科学会雑誌. 2017.08; 59 (1): 11-17. ( 医中誌 )

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