Personnel Information

写真a

KOMATSU Keiji


Job title

Junior Associate Professor

Campus Career 【 display / non-display

  • 2016.10
    -
    2017.03
    Tokyo Medical and Dental University, (Old Organization)Dental Hospital, Trainee Resident
  • 2017.04
    -
    2018.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Science and Technology, Student
  • 2018.04
    -
    2021.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Division of Bio-Matrix, Department of Periodontology, Graduate Student
  • 2018.04
    -
    2021.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Periodontology, Graduate Student
  • 2021.11
    -
    2022.04
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Health Sciences and Biomedical Engineering, Department of Lifetime Oral Health Care Sciences, Visiting Lecturer
  • 2022.05
    -
    2023.04
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Health Sciences and Biomedical Engineering, Department of Lifetime Oral Health Care Sciences, Visiting Lecturer
  • 2023.05
    -
    2024.04
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Health Sciences and Biomedical Engineering, Department of Lifetime Oral Health Care Sciences, Visiting Lecturer
  • 2024.05
    -
    2024.09
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Biomedical Sciences and Engineering, Division of Oral Health Sciences, Department of Lifetime Oral Health Care Sciences, Visiting Lecturer
  • 2024.10
    -
    2024.11
    Institute of Science Tokyo, Visiting Lecturer
  • 2024.12
    -
    Now
    Institute of Science Tokyo, -, Graduate Schools, Division of Oral Health Sciences, Department of Lifetime Oral Health Care Sciences, Junior Associate Professor

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Published Papers & Misc 【 display / non-display

  1. Keiji Komatsu, Denny Chao, Takanori Matsuura, Daisuke Kido, Takahiro Ogawa. Advancing osseointegration research: A dynamic three-dimensional (3D) in vitro culture model for dental implants J Dent Sci. 2025.01; 20 (1): 350-360. ( PubMed, DOI )

  2. Nagai, T; Shiba, T; Komatsu, K; Watanabe, T; Nemoto, T; Maekawa, S; Kobayashi, R; Matsumura, S; Ohsugi, Y; Katagiri, S; Takeuchi, Y; Iwata, T. Optimal 16S rRNA gene amplicon sequencing analysis for oral microbiota to avoid the potential bias introduced by trimming length, primer, and database MICROBIOLOGY SPECTRUM. 2024.12; 12 (12): e0351223. ( PubMed, DOI )

  3. Matsuura, T; Komatsu, K; Suzumura, T; Stavrou, S; Juanatas, ML; Park, W; Ogawa, T. Enhanced functionality and migration of human gingival fibroblasts on vacuum ultraviolet light-treated titanium: An implication for mitigating cellular stress to improve peri-implant cellular reaction JOURNAL OF PROSTHODONTIC RESEARCH. 2024.08; ( PubMed, DOI )

  4. Denny Chao, Keiji Komatsu, Takanori Matsuura, James Cheng, Stella C Stavrou, Jay Jayanetti, Ting-Ling Chang, Takahiro Ogawa. Human Gingival Fibroblast Growth and Function in Response to Laser-Induced Meso- and Microscale Hybrid Topography on Dental Implant Healing Abutments. Int J Oral Maxillofac Implants. 2024.08; 39 (4): 603-614. ( PubMed, DOI )

  5. Watanabe, K; Maruyama, Y; Mikami, R; Komatsu, K; Kikuchi, K; Hotta, K; Yoshikawa, T; Ogasawara, K; Hattori, A; Arakawa, S. Highly purified hypochlorous acid water facilitates glucose metabolism and memory formation in type 2 diabetic mice associated with altered-gut microbiota SCIENTIFIC REPORTS. 2024.07; 14 (1): 16107. ( PubMed, DOI )

  6. Keiji Komatsu, Takanori Matsuura, James Cheng, Daisuke Kido, Wonhee Park, Takahiro Ogawa. Nanofeatured surfaces in dental implants: contemporary insights and impending challenges. Int J Implant Dent. 2024.07; 10 (1): 34. ( PubMed, DOI )

  7. Takanori Matsuura, Keiji Komatsu, James Cheng, Gunwoo Park, Takahiro Ogawa. Beyond microroughness: novel approaches to navigate osteoblast activity on implant surfaces. Int J Implant Dent. 2024.07; 10 (1): 35. ( PubMed, DOI )

  8. Gunwoo Park, Takanori Matsuura, Keiji Komatsu, Takahiro Ogawa. Optimizing implant osseointegration, soft tissue responses, and bacterial inhibition: A comprehensive narrative review on the multifaceted approach of the UV photofunctionalization of titanium. J Prosthodont Res. 2024.06; ( PubMed, DOI )

  9. Keiji Komatsu, Takanori Matsuura, Takahiro Ogawa. Achieving Complete Human Gingival Fibroblast Collagen Coverage on Implant Abutments through Vacuum Ultraviolet (VUV) Photofunctionalization. Int J Oral Maxillofac Implants. 2024.04; 0 (0): 1-32. ( PubMed, DOI )

  10. Takahiko Nagai, Takahiko Shiba, Keiji Komatsu, Shunsuke Matsumura, Tatsuro Koyanagi, Takashi Nemoto, Ryota Kobayashi, Yasuo Takeuchi, Takanori Iwata. Characterizing Bacterial Communities among Healthy, Peri-implant Mucositis, and Peri-implantitis Statuses by 16S rRNA gene amplicon sequencing 口腔病学会雑誌. 2024.03; 91 (1):

  11. Shiba T, Komatsu K, Takeuchi Y, Koyanagi T, Taniguchi Y, Takagi T, Maekawa S, Nagai T, Kobayashi R, Matsumura S, Katagiri S, Izumi Y, Aoki A, Iwata T. Novel flowchart guiding the non-surgical and surgical management of peri-implant complications: a narrative review Bioenginnering. 2024.01; 11 (2): 118.

  12. Komatsu, K; Matsuura, T; Suzumura, T; Ogawa, T. Genome-wide transcriptional responses of osteoblasts to different titanium surface topographies MATERIALS TODAY BIO. 2023.12; 23 100852. ( PubMed, DOI )

  13. Takanori Matsuura, Stella Stavrou, Keiji Komatsu, James Cheng, Alisa Pham, Stephany Ferreira, Tomomi Baba, Ting-Ling Chang, Denny Chao, Takahiro Ogawa. Disparity in the Influence of Implant Provisional Materials on Human Gingival Fibroblasts with Different Phases of Cell Settlement: An In Vitro Study. Int J Mol Sci. 2023.12; 25 (1): ( PubMed, DOI )

  14. Toyoshima, K; Ohsugi, Y; Lin, PY; Komatsu, K; Shiba, T; Takeuchi, Y; Hirota, T; Shimohira, T; Tsuchiya, Y; Katagiri, S; Iwata, T; Aoki, A. Blue Light-Emitting Diode Irradiation Without a Photosensitizer Alters Oral Microbiome Composition of Ligature-Induced Periodontitis in Mice PHOTOBIOMODULATION PHOTOMEDICINE AND LASER SURGERY. 2023.10; 41 (10): 549-559. ( PubMed, DOI )

  15. Kido, D; Komatsu, K; Suzumura, T; Matsuura, T; Cheng, JM; Kim, J; Park, W; Ogawa, T; Canullo, L. Influence of Surface Contaminants and Hydrocarbon Pellicle on the Results of Wettability Measurements of Titanium INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023.10; 24 (19): ( PubMed, DOI )

  16. Toshikatsu Suzumura, Takanori Matsuura, Keiji Komatsu, Yoshihiko Sugita, Hatsuhiko Maeda, Takahiro Ogawa. Vacuum Ultraviolet (VUV) Light Photofunctionalization to Induce Human Oral Fibroblast Transmigration on Zirconia. Cells. 2023.10; 12 (21): ( PubMed, DOI )

  17. Shiba T, Komatsu K, Watanabe T, Takeuchi Y, Nemoto T, Ohsugi Y, Katagiri S, Shimogishi M, Marukawa E, Iwata T. Peri-implantitis management by resective surgery combined with implantoplasty and Er:YAG laser irradiation, accompanied by free gingival graft: a case report. Therapeutic advances in chronic disease. 2023.06; 14 20406223231174816. ( PubMed, DOI )

  18. Kataoka A, Shiba T, Katagiri S, Koyama S, Kito K, Ota T, Katayama T, Ohsugi Y, Nagai T, Kobayashi R, Komatsu K, Urata M, Imazuru T, Iwata T, Kozuma K. Novel and Efficient Method for Diagnosing Infective Endocarditis Using 16S Ribosomal RNA Gene Amplicon Sequence JACC Case Reports. 2023.04; 11 101793. ( PubMed, DOI )

  19. Hiroaki Kitajima, Keiji Komatsu, Takanori Matsuura, Ryotaro Ozawa, Juri Saruta, Samira Rahim Taleghani, James Cheng, Takahiro Ogawa. Impact of nano-scale trabecula size on osteoblastic behavior and function in a meso-nano hybrid rough biomimetic zirconia model. J Prosthodont Res. 2023.04; 67 (2): 288-299. ( PubMed, DOI )

  20. Matsuura, T; Komatsu, K; Choi, K; Suzumura, T; Cheng, JM; Chang, TL; Chao, DY; Ogawa, T. Conditional Mitigation of Dental-Composite Material-Induced Cytotoxicity by Increasing the Cure Time JOURNAL OF FUNCTIONAL BIOMATERIALS. 2023.03; 14 (3): ( PubMed, DOI )

  21. Toshikatsu Suzumura, Takanori Matsuura, Keiji Komatsu, Takahiro Ogawa. A Novel High-Energy Vacuum Ultraviolet Light Photofunctionalization Approach for Decomposing Organic Molecules around Titanium. Int J Mol Sci. 2023.01; 24 (3): ( PubMed, DOI )

  22. Komatsu, K; Hamajima, K; Ozawa, R; Kitajima, H; Matsuura, T; Ogawa, T. Novel Tuning of PMMA Orthopedic Bone Cement Using TBB Initiator: Effect of Bone Cement Extracts on Bioactivity of Osteoblasts and Osteoclasts CELLS. 2022.12; 11 (24): ( PubMed, DOI )

  23. Takanori Matsuura, Keiji Komatsu, Denny Chao, Yu-Chun Lin, Nimish Oberoi, Kalie McCulloch, James Cheng, Daniela Orellana, Takahiro Ogawa. Cell Type-Specific Effects of Implant Provisional Restoration Materials on the Growth and Function of Human Fibroblasts and Osteoblasts. Biomimetics (Basel). 2022.12; 7 (4): ( PubMed, DOI )

  24. Takanori Matsuura, Keiji Komatsu, Takahiro Ogawa. N-Acetyl Cysteine-Mediated Improvements in Dental Restorative Material Biocompatibility. Int J Mol Sci. 2022.12; 23 (24): ( PubMed, DOI )

  25. Hiroaki Kitajima, Makoto Hirota, Keiji Komatsu, Hitoshi Isono, Takanori Matsuura, Kenji Mitsudo, Takahiro Ogawa. Ultraviolet Light Treatment of Titanium Microfiber Scaffolds Enhances Osteoblast Recruitment and Osteoconductivity in a Vertical Bone Augmentation Model: 3D UV Photofunctionalization. Cells. 2022.12; 12 (1): ( PubMed, DOI )

  26. Toshikatsu Suzumura, Takanori Matsuura, Keiji Komatsu, Takahiro Ogawa. Decomposing Organic Molecules on Titanium with Vacuum Ultraviolet Light for Effective and Rapid Photofunctionalization. J Funct Biomater. 2022.12; 14 (1): ( PubMed, DOI )

  27. Yuki Nagasawa, Sayaka Katagiri, Kazuharu Nakagawa, Tomomitsu Hirota, Kanako Yoshimi, Aritoshi Uchida, Masahiro Hatasa, Keiji Komatsu, Takahiko Shiba, Yujin Ohsugi, Naofumi Uesaka, Takanori Iwata, Haruka Tohara. Xanthan gum-based fluid thickener decreases postprandial blood glucose associated with increase of Glp1 and Glp1r expression in ileum and alteration of gut microbiome 2022.11;

  28. Nagasawa Y, Katagiri S, Nakagawa K, Hirota T, Yoshimi K, Uchida A, Hatasa M, Komatsu K, Shiba T, Ohsugi Y, Uesaka N, Iwata T, Tohara H. Xanthan gum-based fluid thickener decreases postprandial blood glucose associated with increase of Glp1 and Glp1r expression in ileum and alteration of gut microbiome Journal of Functional Foods. 2022.11; e-pub

  29. Ohsugi Y, Hatasa M, Katagiri S, Hirota T, Shimohira T, Shiba T, Komatsu K, Tsuchiya Y, Fukuba S, Lin P, Toyoshima K, Maekawa S, Niimi H, Iwata T, Aoki A. High-frequency pulsed diode laser irradiation inhibits bone resorption in mice with ligature-induced periodontitis Journal of Clinical Periodontology. 2022.07; e-pub ( PubMed, DOI )

  30. Shiba T, Katagiri S, Komatsu K, Nemoto T, Takeuchi Y, Chen B, Zhou YS, Iwata T. Treatment of peri-implantitis caused by malpositioning and an extra implant: a case report Int J Periodontics Restorative Dent. 2022.01; 42 (1): e15-e20. ( PubMed, DOI )

  31. Shimogishi M, Watanabe T, Shibasaki M, Shiba T, Komatsu K, Nemoto T, Ishihara K, Nakano Y, Iwata T, Kasugai S, Nakagawa I. Patient-specific establishment of bacterial composition within the peri-implant microbiota during the earliest weeks after implant uncovering. Journal of Periodontal Research. 2021.10; 56 (5): 964-971. ( PubMed, DOI )

  32. Nemoto T, Shiba T, Komatsu K, Watanabe T, Shimogishi M, Shibasaki M, Koyanagi T, Nagai T, Katagiri S, Takeuchi Y, Iwata T. Discrimination of bacterial community structures among healthy, gingivitis, and periodontitis statuses through integrated metatranscriptomic and network analyses. mSystems. 2021.10; e0088621. ( PubMed, DOI )

  33. Shiba Takahiko, Komatsu Keiji, Sudo Takeaki, Sawafuji Rikai, Saso Aiko, Ueda Shintaroh, Watanabe Takayasu, Nemoto Takashi, Kano Chihiro, Nagai Takahiko, Ohsugi Yujin, Katagiri Sayaka, Takeuchi Yasuo, Kobayashi Hiroaki, Iwata Takanori. Comparison of Periodontal Bacteria of Edo and Modern Periods Using Novel Diagnostic Approach for Periodontitis With Micro-CT FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2021.09; 11 723821. ( PubMed, DOI )

  34. Saida H, Fukuba S, Shiba T, Komatsu K, Iwata T, Nitta H. Two-stage approach for class II mandibular furcation defect with insufficient keratinized mucosa: a case report with 3 years' follow-up. The Journal of international medical research. 2021.09; 49 (9): 3000605211044595. ( PubMed, DOI )

  35. Lin P, Niimi H, Ohsugi Y, Tsuchiya Y, Shimohira T, Komatsu K, Liu A, Shiba T, Aoki A, Iwata T, Katagiri S. Application of Ligature-Induced Periodontitis in Mice to Explore the Molecular Mechanism of Periodontal Disease International Journal of Molecular Sciences. 2021.08; 22 (16): 8900. ( PubMed, DOI )

  36. Shiba T, Watanabe T, Komatsu K, Koyanagi T, Nemoto T, Ohsugi Y, Michi Y, Katagiri S, Takeuchi Y, Ishihara K, Iwata T. Non-surgical treatment for periodontitis and peri-implantitis: longitudinal clinical and bacteriological findings-A case report with a 7-year follow-up evaluation. SAGE open medical case reports. 2021; 9 2050313X211029154. ( PubMed, DOI )

  37. Komatsu K, Shiba T, Takeuchi Y, Watanabe T, Koyanagi T, Nemoto T, Shimogishi M, Shibasaki M, Katagiri S, Kasugai S, Iwata T. Discriminating Microbial Community Structure Between Peri-Implantitis and Periodontitis With Integrated Metagenomic, Metatranscriptomic, and Network Analysis Frontiers in Cellular and Infection Microbiology, Tokyo Medical and Dental University. 2020.12; 10 596490. ( DOI )

  38. Watanabe Kazuki, Katagiri Sayaka, Takahashi Hirokazu, Sasaki Naoki, Maekawa Shogo, Komazaki Rina, Hatasa Masahiro, Kitajima Yoichiro, Maruyama Yusuke, Shiba Takahiko, Komatsu Keiji, Ohsugi Yujin, Tanaka Kenichi, Matsuzawa Ayumi, Hirota Tomomitsu, Tohara Haruka, Eguchi Yuichiro, Anzai Keizo, Hattori Atsuhiko, Iwata Takanori. Porphyromonas gingivalis impairs glucose uptake in skeletal muscle associated with altering gut microbiota FASEB JOURNAL. 2020.11; 35 (2): e21171. ( PubMed, DOI )

  39. Katagiri S, Shiba T, Tohara H, Yamaguchi K, Hara K, Nakagawa K, Komatsu K, Watanabe K, Ohsugi Y, Maekawa S, Iwata T. Re-initiation of Oral Food Intake Following Enteral Nutrition Alters Oral and Gut Microbiota Communities Frontiers in Cellular and Infection Microbiology. 2019.12; 9 434. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  1. Koki Takada, Takahiko Shiba, Takahiko Nagai, Ryota Kobayashi, Shunsuke Matsumura, Keiji Komatsu, Sayaka Katagiri, Takanori Iwata . Exploring the Relationship between Oral Bacteria and Infective Endocarditis through Next-Generation Sequencing. 口腔病学会 2024.12.06

  2. Ryota Kobayashi, Takahiko Shiba, Takahiko Nagai, Keiji Komatsu, Shunsuke Matsumura, Takashi Nemoto, Koki Takada, Yasuo Takeuchi, Takanori Iwata. Shifting the Microbiome Following Non-Surgical Treatment for Each Periodontal Status. The 110th Annual Meeting of the American Academy of Periodontology 2024.11.06

  3. Takahiko Nagai1, Takahiko Shiba1, Keiji Komatsu2, Shunsuke Matsumura1, Tatsuro Koyanagi1, Takashi Nemoto, Ryota Kobayashi, Yasuo Takeuchi, Takanori Iwata. Characterizing Bacterial Communities among Healthy, Peri-implant Mucositis, and Peri-implantitis Statuses by 16S rRNA gene amplicon sequencing.. American Academy of Periodontology, 110th ANNUAL MEETING 2024.10.31

  4. Daisuke Kido, Keiji Komatsu, Toshikatsu Suzumura, Takanori Matsuura, Takahiro Ogawa. Clinical Determinants of Hydrophilic State of Titanium Surfaces. the 2023 IADR/LAR General Session & Exhibition with WCPD 2023.06.24

  5. Komatsu Keiji, Matsuura Takanori, Ogawa Takahiro. UV treatment of healing abutments maximizes human gingival fibroblast function by regulating gene expression. Academy of Osseointegration Annual Meeting 2023.03.17 Phoenix, USA

  6. Suzumura Toshikatsu, Matsuura Takanori, Komatsu Keiji, Vanjari Gauri, Ogawa Takahiro. Investigations of vacuum-UV treatment to maximize the effectiveness of organic compounds degradation. Academy of Osseointegration Annual Meeting 2023.03.17 Phoenix, USA

  7. Matsuura Takanori, Taleghani Samira, Shokeen Bhumika, Komatsu Keiji, Kitajima Hiroaki, Cheng James, Lux Renate, Ogawa Takahiro. Distinct behavior and microbiome of oral biofilm formed on titanium and zirconia. Academy of Osseointegration Annual Meeting 2023.03.17 Phoenix, USA

  8. Nagai Takahiko, Shiba Takahiko, Komatsu Keiji, Nemoto Takashi, Kobayashi Ryouta, Takeuchi Yasuo, Iwata Takanori. Determining the best approach for sequencing analysis of oral microbiota. The 108th Annual Meeting of the American Academy of Periodontology in collaboration with the Japanese Society of Periodontology and Japanese Academy of Clinical Periodontology 2022.10 Phoenix, USA

  9. 下平 剛, 大杉勇人, 片桐さやか, 芝多佳彦, 駒津匡二, 劉 安豪, 林 培雅, 豊嶋啓汰, 青木 章. 近赤外線光線療法の薬剤関連性顎骨壊死への応用と分子機構の解明. 第64回歯科基礎医学会学術大会 2022.09.17 徳島

  10. Komatsu K, Takeuchi Y, Shiba T, Watanabe T, Shimogishi M, Shibasaki M, Nemoto T, Koyanagi T, Katagiri S, Iwata T. Omics analysis defines differences in microbial community structure between peri-implantitis and periodontitis. The 68th Annual Meeting of Japan Dental Research 2020.11.07 Virtual

  11. Komatsu K, Shiba T, Watanabe T, Nemoto T, Koyanagi T, Iwata T. Non-surgical treatment and microbiome of periodontitis and peri-implantitis: seven-year. The 106th Annual Meeting of the American Academy of Periodontology in collaboration with the Japanese Society of Periodontology and Japanese Academy of Clinical Periodontology 2020.11.06 Virtual

  12. 芝 多佳彦,竹内康雄,片桐さやか,駒津匡二,小柳達郎,根本昂,青木章. オミックス解析による口腔内複合感染症の病因および病態機序の解明. 第83回 口腔病学会学術大会 2018.12.01 東京都文京区

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Awards & Honors 【 display / non-display

  • UCLA Science Day Poster Presentation First Place Award,UCLA School of Dentistry,2024.06

  • UCLA Science Day Poster Presentation First Place Award,UCLA School of Dentistry,2022.06