Personnel Information

写真a

FUJIMARU Takuya


Job title

Visiting Lecturer
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Campus Career 【 display / non-display 】

  • 2016.04
    -
    2020.03
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Systemic Organ Regulation， Nephrology， Graduate Student
  • 2020.05
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    2021.04
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Systemic Organ Regulation， Department of Nephrology， Visiting Lecturer
  • 2021.05
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    2022.04
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Systemic Organ Regulation， Department of Nephrology， Visiting Lecturer
  • 2022.05
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    2023.04
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Systemic Organ Regulation， Department of Nephrology， Visiting Lecturer
  • 2023.05
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    2024.04
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Systemic Organ Regulation， Department of Nephrology， Visiting Lecturer
  • 2024.05
    -
    Now
    Tokyo Medical and Dental University， Graduate School of Medical and Dental Sciences， Medical and Dental Sciences， Division of Systemic Organ Regulation， Department of Nephrology， Visiting Lecturer

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Published Papers & Misc 【 display / non-display 】

  1. Takahashi N, Kikuchi H, Usui A, Furusho T, Fujimaru T, Fujiki T, Yanagi T, Matsuura Y, Asano K, Yamamoto K, Ando F, Susa K, Mandai S, Mori T, Rai T, Uchida S, Arita M, Sohara E. Deletion of Alox15 improves kidney dysfunction and inhibits fibrosis by increased PGD<sub>2</sub> in the kidney. Clinical and experimental nephrology. 2021.02; ( PubMed, DOI )

  2. Mori Takayasu, Chiga Motoko, Fujimaru Takuya, Kawamoto Ryosuke, Mandai Shintaro, Nanamatsu Azuma, Nomura Naohiro, Ando Fumiaki, Susa Koichiro, Sohara Eisei, Rai Tatemitsu, Uchida Shinichi. Phenotypic differences of mutation-negative cases in Gitelman syndrome clinically diagnosed in adulthood HUMAN MUTATION. 2020.12; 42 (3): 300-309. ( PubMed, DOI )

  3. Sekine Akinari, Hoshino Junichi, Fujimaru Takuya, Suwabe Tatsuya, Mizuno Hiroki, Kawada Masahiro, Hiramatsu Rikako, Hasegawa Eiko, Yamanouchi Masayuki, Hayami Noriko, Mandai Shintaro, Chiga Motoko, Kikuchi Hiroaki, Ando Fumiaki, Mori Takayasu, Sohara Eisei, Uchida Shinichi, Sawa Naoki, Takaichi Kenmei, Ubara Yoshifumi. Genetics May Predict Effectiveness of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease AMERICAN JOURNAL OF NEPHROLOGY. 2020.09; 51 (9): 745-751. ( PubMed, DOI )

  4. Ishii T, Fujimaru T, Nakano E, Takahashi O, Nakayama M, Yamauchi T, Komatsu Y. Association between chronic kidney disease and mortality in stage IV cancer. International journal of clinical oncology. 2020.09; 25 (9): 1587-1595. ( PubMed, DOI )

  5. Fujimaru Takuya, Sohara Eisei. Copy Number Variation: A New Genetic Form of Polycystic Kidney and Liver Disease KIDNEY INTERNATIONAL REPORTS. 2020.05; 5 (5): 575-576. ( PubMed, DOI )

  6. Furusho T, Sohara E, Mandai S, Kikuchi H, Takahashi N, Fujimaru T, Hashimoto H, Arai Y, Ando F, Zeniya M, Mori T, Susa K, Isobe K, Nomura N, Yamamoto K, Okado T, Rai T, Uchida S. Renal TNFα activates the WNK phosphorylation cascade and contributes to salt-sensitive hypertension in chronic kidney disease. Kidney international. 2020.02; ( PubMed, DOI )

  7. Saito D, Fujimaru T, Inoue Y, Hirayama T, Ezaki I, Kin H, Shuo T, Nakayama M, Komatsu Y. Serial measurement of electrolyte and citrate concentrations in blood-primed continuous hemodialysis circuits during closed-circuit dialysis. Pediatric nephrology (Berlin, Germany). 2020.01; 35 (1): 127-133. ( PubMed, DOI )

  8. Fujimaru T, Shimada K, Hamada T, Watanabe K, Ito Y, Nagahama M, Taki F, Isokawa S, Hifumi T, Otani N, Nakayama M. Development of acute kidney injury with massive granular casts and microscopic hematuria in patients with COVID-19: two case presentations with literature review. Renal replacement therapy. 2020; 6 (1): 59. ( PubMed, DOI )

  9. Sakoh Takashi, Sekine Akinari, Mori Takayasu, Mizuno Hiroki, Kawada Masahiro, Hiramatsu Rikako, Hasegawa Eiko, Hayami Noriko, Yamanouchi Masayuki, Suwabe Tatsuya, Sawa Naoki, Ubara Yoshifumi, Fujimaru Takuya, Sohara Eisei, Shinichi Uchida, Hoshino Junichi, Takaichi Kenmei. A familial case of pseudohypoaldosteronism type II (PHA2) with a novel mutation (D564N) in the acidic motif in WNK4 MOLECULAR GENETICS & GENOMIC MEDICINE. 2019.06; 7 (6): e705. ( PubMed, DOI )

  10. Sekine A, Fujimaru T, Hoshino J, Suwabe T, Oguro M, Mizuno H, Kawada M, Sumida K, Hiramatsu R, Hasegawa E, Yamanouchi M, Hayami N, Mandai S, Chiga M, Kikuchi H, Ando F, Mori T, Sohara E, Uchida S, Sawa N, Takaichi K, Ubara Y. Genotype-Clinical Correlations in Polycystic Kidney Disease with No Apparent Family History. American journal of nephrology. 2019.02; 49 (3): 233-240. ( PubMed, DOI )

  11. Watanabe S, Ino J, Fujimaru T, Taneda S, Akihisa T, Makabe S, Kataoka H, Mori T, Sohara E, Uchida S, Nitta K, Mochizuki T. PKD1 mutation may epistatically ameliorate nephronophthisis progression in patients with NPHP1 deletion. Clinical case reports. 2019.02; 7 (2): 336-339. ( PubMed, DOI )

  12. Hashimoto Hiroko, Nomura Naohiro, Shoda Wakana, Isobe Kiyoshi, Kikuchi Hiroaki, Yamamoto Kouhei, Fujimaru Takuya, Ando Fumiaki, Mori Takayasu, Okado Tomokazu, Rai Tatemitsu, Uchida Shinichi, Sohara Eisei. Metformin increases urinary sodium excretion by reducing phosphorylation of the sodium-chloride cotransporter METABOLISM-CLINICAL AND EXPERIMENTAL. 2018.08; 85 23-31. ( PubMed, DOI )

  13. Toriu N, Mizuno H, Sawa N, Sumida K, Suwabe T, Hayami N, Sekine A, Yamanouchi M, Hoshino J, Takaichi K, Yanagita M, Fujimaru T, Mori T, Sohara E, Uchida S, Ubara Y. Everolimus Reduces the Size of Tuberous Sclerosis Complex-Related Huge Renal Angiomyolipomas Exceeding 20 cm in the Longest Diameter. Case reports in oncology. 2018.05; 11 (2): 258-267. ( PubMed, DOI )

  14. T Fujimaru, T Mori, A Sekine, S Mandai, M Chiga, H Kikuchi, F Ando, Y Mori, N Nomura, S Iimori, S Naito, T Okado, T Rai, J Hoshino, Y Ubara, S Uchida, E Sohara. Kidney enlargement and multiple liver cyst formation implicate mutations in PKD1/2 in adult sporadic polycystic kidney disease. Clin. Genet.. 2018.03; ( PubMed, DOI )

  15. Toriu N, Hoshino J, Kobori S, Watanabe S, Oguro M, Oshima Y, Hiramatsu R, Mizuno H, Ikuma D, Sekine A, Hayami N, Sumida K, Yamanouchi M, Hasegawa E, Sawa N, Takaichi K, Yanagita M, Fujimaru T, Sohara E, Uchida S, Ubara Y. Transcatheter Arterial Embolization Therapy for Huge Renal Cysts: Two Case Reports. Case reports in nephrology and dialysis. 2018.01; 8 (1): 82-89. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display 】

  1. Takuya Fujimaru, Takayasu Mori, Michio Nagata, Shintaro Mandai, Motoko Chiga, Hiroaki Kikuchi, Fumiaki Ando, Yutaro Mori, Koichiro Susa, Kiyoshi Isobe, Soichiro Iimori, Naohiro Nomura, Shotaro Naito, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara.. Tubular basement membrane duplication and cell interposition are distinctive histological findings in the adult patients genetically diagnosed with NPHP-RCs. ASN Kidney Week 2019 2019.11

  2. Fujimaru T, Mori T, Mandai S, Chiga M, Kikuchi H, Ando F, Mori Y, Susa K, Isobe K, Iimori S, Nomura N, Naito S, Okado T, Rai T, Nagatsuji K, Nagahama K, Mishima E, Mochizuki T, Sekine A, Hoshino J, Ubara Y, Uchida S, Sohara E.. Genomic Background of Adults with Suspected Ciliopathy on Renal Biopsy.. The 52nd Annual Meeting of American Society of Nephrology, Kidney Week 2018 2018.10.26 San Diego

  3. Takuya Fujimaru, Takayasu Mori, Akinari Sekine, Shintaro Mandai, Motoko Chiga, Hiroaki Kikuchi, Fumiaki Ando, Yutaro Mori, Naohiro Nomura, Soichiro Iimori, Shotaro Naito, Tomokazu Okado, Tatemitsu Rai, Junichi Hoshino, Yoshifumi Ubara, Shinichi Uchida, Eisei Sohara. Genomic diagnosis of adult polycystic kidney disease with no family history. ISN Frontiers Meetings 2018 2018.02.24 Tokyo, Japan

  4. Takuya Fujimaru, Takayasu Mori, Akinari Sekine, Shintaro Mandai, Motoko Chiga, Hiroaki Kikuchi , Fumiaki Ando, Yutaro Mori, Naohiro Nomura, Shotaro Naito, Tomokazu Okado, Tatemitsu Rai, Junichi Hoshino, Yoshifumi Ubara, Shinichi Uchida, Eisei Sohara. Genomic background of adult polycystic kidney disease patients without a family history. Kidney Week 2017 2017.11.03 New Orleans, LA

  5. Takuya Fujimaru, Takayasu Mori, Shintaro Mandai, Motoko Chiga, Hiroaki Kikuchi, Fumiaki Ando, Yutaro Mori, Naohiro Nomura, Shotaro Naito, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara. Development of a Customized Diagnostic Panel for Targeted Exome Sequencing of Polycystic Kidney Diseases. Kidney Week 2016 2016.11.19 Chicago, IL

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Awards & Honors 【 display / non-display 】

  • Takuya Fujimaru. Top 10% Ranked Poster Award，International Society of Nephrology，2018.02

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Others 【 display / non-display 】

  • Genetic analysis sheds light on the role of IFT140 in polycystic kidney disease，2024.09

  • Genetic Analysis Reveals True Origin of Chronic Kidney Disease in Undiagnosed Patients，2024.04

  • Finding clues to nephronophthisis in adults，2021.04

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