Personnel Information

写真a

OHSUGI Yujin


Job title

Assistant Professor

Graduating School 【 display / non-display

  • Showa University, Faculty of Dentistry, 2014.03, Graduated

Graduate School 【 display / non-display

  • Tokyo Medical and Dental University, Doctor's Course, 2019.03, Completed

Campus Career 【 display / non-display

  • 2015.04
    -
    2019.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Periodontology, Graduate Student
  • 2019.04
    -
    2019.08
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Division of Bio-Matrix, Department of Periodontology, Visiting Lecturer
  • 2019.09
    -
    2022.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Periodontology, Dental Resident
  • 2022.04
    -
    Now
    Tokyo Medical and Dental University, Tokyo Medical and Dental University, Division of Clinical Dentistry, Department of Conservative Dentistry, Periodontics, Assistant Professor
  • 2022.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Periodontology, Assistant Professor

Research Areas 【 display / non-display

  • Conservative dentistry

 

Published Papers & Misc 【 display / non-display

  1. Aoki A, Mizutani K, Taniguchi Y, Lin T, Ohsugi Y, Mikami R, Katagiri S, Meinzer W, Iwata T. Current status of Er:YAG laser in periodontal surgery. The Japanese dental science review. 2024.12; 60 1-14. ( PubMed, DOI )

  2. Lin P, Liu A, Tsuchiya Y, Noritake K, Ohsugi Y, Toyoshima K, Tsukahara Y, Shiba T, Nitta H, Aoki A, Iwata T, Katagiri S. Association between periodontal disease and chronic obstructive pulmonary disease Japanese Dental Science Review. 2023.12; 59 389-402. ( PubMed, DOI )

  3. Lin P, Niimi H, Hirota T, Ohsugi Y, Shimohira T, Toyoshima K, Katagiri S, Iwata T, Aoki A. Effects of low-level Er:YAG laser irradiation on proliferation and gene expression in primary gingival fibroblasts isolated from mouse maxilla J Biophotonics. 2023.11; e202300166. ( PubMed, DOI )

  4. Katagiri S, Ohsugi Y, Shiba T, Yoshimi K, Nakagawa K, Nagasawa Y, Uchida A, Liu A, Lin P, Tsukahara Y, Iwata T, Tohara H. Homemade blenderized tube feeding improves gut microbiome communities in children with enteral nutrition Frontiers in Microbiology. 2023.08; 14 1215236.

  5. Katagiri S, Ohsugi Y, Shiba T, Yoshimi K, Nakagawa K, Nagasawa Y, Uchida A, Liu A, Lin P, Tsukahara Y, Iwata T, Tohara H.. Homemade blenderized tube feeding improves gut microbiome communities in children with enteral nutrition Frontiers in Microbiology. 2023.08; 23 (14): 1214236.

  6. Shiba T, Komatsu K, Watanabe T, Takeuchi Y, Nemoto T, Ohsugi Y, Katagiri S, Shimogishi M, Marukawa E, Iwata T. Peri-implantitis management by resective surgery combined with implantoplasty and Er:YAG laser irradiation, accompanied by free gingival graft: a case report. Therapeutic advances in chronic disease. 2023.06; 14 20406223231174816. ( PubMed, DOI )

  7. Aoki A, Mizutani K, Mikami R, Ohsugi Y, Kobayashi H, Akizuki T, Taniguchi Y, Takeuchi Y, Katagiri S, Sasaki Y, Komaki M, Meinzer W, Izumi Y, Iwata T. Er:YAG laser-assisted comprehensive periodontal pocket therapy for residual periodontal pocket treatment: A randomized controlled clinical trial. Journal of Periodontology. 2023.04; e-pub ( PubMed, DOI )

  8. Kataoka A, Shiba T, Katagiri S, Koyama S, Kito K, Ota T, Katayama T, Ohsugi Y, Nagai T, Kobayashi R, Komatsu K, Urata M, Imazuru T, Iwata T, Kozuma K. Novel and Efficient Method for Diagnosing Infective Endocarditis Using 16S Ribosomal RNA Gene Amplicon Sequence JACC Case Reports. 2023.04; 11 101793. ( PubMed, DOI )

  9. Ohsugi Y, Hatasa M, Katagiri S, Hirota T, Shimohira T, Shiba T, Komatsu K, Tsuchiya Y, Fukuba S, Lin P, Toyoshima K, Maekawa S, Niimi H, Iwata T, Aoki A. High-frequency pulsed diode laser irradiation inhibits bone resorption in mice with ligature-induced periodontitis Journal of Clinical Periodontology. 2022.12; 49 (12): 1275-1288. ( PubMed, DOI )

  10. Nagasawa Y, Katagiri S, Nakagawa K, Hirota T, Yoshimi K, Uchida A, Hatasa M, Komatsu K, Shiba T, Ohsugi Y, Uesaka N, Iwata T, Tohara H. Xanthan gum-based fluid thickener decreases postprandial blood glucose associated with increase of Glp1 and Glp1r expression in ileum and alteration of gut microbiome Journal of Functional Foods. 2022.11;

  11. Yoshida S, Hatasa M, Ohsugi Y, Tsuchiya Y, Liu A, Niimi H, Morita K, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Okano T, Hirose A, Ibi R, Noritake K, Tomiga Y, Nitta H, Suzuki T, Takahashi H, Miyasaka N, Iwata T, Katagiri S. Porphyromonas gingivalis administration induces gestational obesity, alters gene expression in the liver and brown adipose tissue in pregnant mice, and causes underweight in fetuses Frontiers in Cellular and Infection Microbiology. 2022.01; 11 745117. ( PubMed, DOI )

  12. Shiba T, Komatsu K, Sudo T, Sawafuji R, Saso A, Ueda S, Watanabe T, Nemoto T, Kano C, Nagai T, Ohsugi Y, Katagiri S, Takeuchi Y, Kobayashi H, Iwata T. Comparison of Periodontal Bacteria of Edo and Modern Periods Using Novel Diagnostic Approach for Periodontitis With Micro-CT. Frontiers in Cellular and Infection Microbiology. 2021.09; 11 723821. ( PubMed, DOI )

  13. Lin P, Niimi H, Ohsugi Y, Tsuchiya Y, Shimohira T, Komatsu K, Liu A, Shiba T, Aoki A, Iwata T, Katagiri S. Application of Ligature-Induced Periodontitis in Mice to Explore the Molecular Mechanism of Periodontal Disease International Journal of Molecular Sciences. 2021.08; 22 (16): 8900. ( PubMed, DOI )

  14. Shimohira T, Niimi H, Ohsugi Y, Tsuchiya Y, Morita K, Yoshida S, Hatasa M, Shiba T, Kadokura H, Yokose S, Katagiri S, Iwata T, Aoki A. Low-Level Erbium-Doped Yttrium Aluminum Garnet Laser Irradiation Induced Alteration of Gene Expression in Osteogenic Cells from Rat Calvariae Photobiomodulation, Photobiomedicine, and Laser Surgery. 2021.07; ( DOI )

  15. Aoki A, Mizutani K, Mikami R, Taniguchi Y, Ohsugi Y, Meinzer W, Izumi Y, Iwata T. Residual periodontal pocket treatment with Er:YAG laser-assisted comprehensive periodontal pocket therapy: a retrospective study. Clinical Oral Investigations. 2021.07; e-pub ( PubMed, DOI )

  16. Shiba T, Watanabe T, Komatsu K, Koyanagi T, Nemoto T, Ohsugi Y, Michi Y, Katagiri S, Takeuchi Y, Ishihara K, Iwata T. Non-surgical treatment for periodontitis and peri-implantitis: longitudinal clinical and bacteriological findings-A case report with a 7-year follow-up evaluation. SAGE open medical case reports. 2021.07; 9 2050313X211029154. ( PubMed, DOI )

  17. Kataoka A, Katagiri S, Kawashima H, Nagura F, Nara Y, Hioki H, Nakashima M, Sasaki N, Hatasa M, Maekawa S, Ohsugi Y, Shiba T, Watanabe Y, Shimokawa T, Iwata T, Kozuma K. Association between Periodontal Bacteria and Degenerative Aortic Stenosis: A Pilot Study Journal of Periodontal and Implant Science. 2021.04; 51 (e9): 1-24.

  18. Hatasa M, Yoshida S, Takahashi H, Tanaka K, Kubotsu Y, Ohsugi Y, Katagiri T, Iwata T, Katagiri S. Relationship between NAFLD and Periodontal Disease from the View of Clinical and Basic Research, and Immunological Response International Journal of Molecular Sciences. 2021.04; 22 (7): 3728.

  19. Hatasa M, Ohsugi Y, Katagiri S, Yoshida S, Niimi H, Morita K, Tsuchiya Y, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Tohara H, Takahashi H, Nitta H, Iwata T. Endotoxemia by Porphyromonas gingivalis alters endocrine functions in brown adipose tissue Frontiers in Cellular and Infection Microbiology. 2021.01; 19 (10): 580577.

  20. Shimohira T, Katagiri S, Ohsugi Y, Hirota T, Hatasa M, Mizutani K, Watanabe K, Niimi H, Iwata T, Aoki A. Comprehensive and Sequential Gene Expression Analysis of Bone Healing Process Following Er:YAG Laser Ablation Photobiomodulation, Photobiomedicine, and Laser Surgery. 2020.12; ( PubMed, DOI )

  21. Ohsugi Y, Niimi H, Shimohira T, Hatasa M, Katagiri S, Aoki A, Iwata T. In vitro cytological responses against laser photobiomodulation for periodontal regeneration International Journal of Molecular Sciences. 2020.11; 21 (23): 9002.

  22. Watanabe Kazuki, Katagiri Sayaka, Takahashi Hirokazu, Sasaki Naoki, Maekawa Shogo, Komazaki Rina, Hatasa Masahiro, Kitajima Yoichiro, Maruyama Yusuke, Shiba Takahiko, Komatsu Keiji, Ohsugi Yujin, Tanaka Kenichi, Matsuzawa Ayumi, Hirota Tomomitsu, Tohara Haruka, Eguchi Yuichiro, Anzai Keizo, Hattori Atsuhiko, Iwata Takanori. Porphyromonas gingivalis impairs glucose uptake in skeletal muscle associated with altering gut microbiota FASEB JOURNAL. 2020.11; 35 (2): e21171. ( PubMed, DOI )

  23. Ohsugi Y, Katagiri S, Hirota T, Niimi H, Hatasa M, Watanabe K, Shimohira T, Mizutani K, Kitazawa M, Matsuzawa A, Kadokura H, Yokose S, Iwata T, Aoki A. Laser irradiation decreases sclerostin expression in bone and osteogenic cells. The FASEB Journal. 2020.08; 34 (9): 12877-12893. ( PubMed, DOI )

  24. Niimi H, Ohsugi Y, Katagiri S, Watanabe K, Hatasa M, Shimohira T, Tsuchiya Y, Maekawa S, Hirota T, Kadokura H, Yokose S, Iwata T, Aoki A. Effects of Low-Level Er:YAG Laser Irradiation on Proliferation and Calcification of Primary Osteoblast-Like Cells Isolated From Rat Calvaria Frontiers in cell and developmental biology. 2020.06; 6 (459):

  25. Tanaka K, Takahashi H, Katagiri S, Sasaki K, Ohsugi Y, Watanabe K, Rasadul IMD, Mine K, Nagafuchi S, Iwata T, Eguchi Y, Anzai K. Combined effect of canagliflozin and exercise training on high-fat diet-fed mice. American journal of physiology. Endocrinology and metabolism. 2020.04; 318 (4): E492-E503. ( PubMed, DOI )

  26. Ogawa M, Katagiri S, Koyanagi T, Maekawa S, Shiba T, Ohsugi Y, Takeuchi Y, Ikawa T, Takeuchi S, Sekiuchi T, Arai Y, Kazama R, Wakabayashi N, Izumi Y, Iwata T. Accuracy of cone beam computed tomography in evaluation of palatal mucosa thickness. Journal of Clinical Periodontology. 2020.01; ( PubMed, DOI )

  27. Hatasa M, Ohsugi Y, Katagiri S, Yoshida S, Niimi H, Morita K, Tsuchiya Y, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Tohara H, Takahashi H, Nitta H, Iwata T.. Endotoxemia by Porphyromonas gingivalis alters endocrine functions in brown adipose tissue Frontiers in Cellular and Infection Microbiology. 2020; 10 580577. ( PubMed, DOI )

  28. Katagiri S, Shiba T, Tohara H, Yamaguchi K, Hara K, Nakagawa K, Komatsu K, Watanabe K, Ohsugi Y, Maekawa S, Iwata T. Re-initiation of Oral Food Intake Following Enteral Nutrition Alters Oral and Gut Microbiota Communities Frontiers in Cellular and Infection Microbiology. 2019.12; 9 434. ( PubMed, DOI )

  29. Maekawa S, Onizuka S, Katagiri S, Hatasa M, Ohsugi Y, Sasaki N, Watanabe K, Ohtsu A, Komazaki R, Ogura K, Miyoshi-Akiyama T, Iwata T, Nitta H, Izumi Y. RNA sequencing for ligature induced periodontitis in mice revealed important role of S100A8 and S100A9 for periodontal destruction. Scientific reports. 2019.10; 9 (1): 14663. ( PubMed, DOI )

  30. Watanabe K, Ohsugi Y, Maekawa S, Sasaki N, Shiba T, Katagiri S, Arakawa S. Ozone Ultrafine Bubble Water improves wound healing via modification of inflammation Journal of the Stomatological Society. 2019.07; 86 (2): 25-34.

  31. Ohsugi Y, Aoki A, Mizutani K, Katagiri S, Komaki M, Noda M, Takagi T, Kakizaki S, Meinzer W, Izumi Y. Evaluation of bone healing following Er:YAG laser ablation in rat calvaria compared with bur drilling Journal of Biophotonics. 2018.10; e201800245. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  1. Lin P, Niimi H, Hirota T, Ohsugi Y, Shimohira T, Toyoshima K, Katagiri K, Iwata T, Aoki A. Effect of low-level Er:YAG laser irradiation on proliferation and gene expression changes of primary gingival fibroblasts isolated from mouse maxilla. The 17th Congress of WFLD, Faculty of Pharmacy 2023.04.16 Wrocław Medical University, Wroclaw

  2. 下平 剛, 大杉勇人, 片桐さやか, 芝多佳彦, 駒津匡二, 劉 安豪, 林 培雅, 豊嶋啓汰, 青木 章. 近赤外線光線療法の薬剤関連性顎骨壊死への応用と分子機構の解明. 第64回歯科基礎医学会学術大会 2022.09.17 徳島

  3. Yoshida S, Hatasa M, Ohsugi Y, Tsuchiya Y, Liu A, Niimi H, Morita K, Shimohira T, Sasaki N, Maekawa S, Shiba T, Hirota T, Noritake K, Nitta H, Katagiri S, Iwata T. Porphyromonas gingivalis administration induces obesity, modifies gene expression in the liver and brown adipose tissue in pregnant mice, and causes underweight in fetuses. Europerio 10 2022.06.15 Copenhagen

  4. Ohsugi Y, Katagiri S, Niimi H, Hatasa M, Watanabe K, Shimohira T, Mizutani K, Kadokura H, Yokose S, Iwata T, Aoki A. Sequential microarray analysis of Er:YAG laser ablated bone tissue. The 99th General Session of the IADR 2021.07.21 Virtual

  5. Shimohira T, Niimi H, Ohsugi Y, Tsuchiya Y, Morita K, Yoshida S, Hatasa M, Shiba T, Kadokura H, Yokose S, Katagiri S, Iwata T, Aoki A. . Low-level Er:YAG laser irradiation induced alteration of gene expression in rat calvarial osteogenic cells. Dental Laser Virtual Scientific Conference 2021 2021.07.16

  6. Katagiri S, Ohsugi Y, Aoki A. Photobiomodulatory suppressive effect of a 910-nm diode laser on periodontal disease progression in mice. Academy of Laser Dentistry 28th Annual Conference 2021.04.08 Virtual

  7. Ohsugi Y, Katagiri S, Aoki A. Novel bone regenerative therapy: sequential microarray analysis of Er:YAG Laser-ablated bone tissue and the modification of gene expression in osteocytes and osteoblasts. Academy of Laser Dentistry 28th Annual Conference 2021.04.08 Virtual

  8. Er:YAGレーザーによるラット頭蓋骨由来初代培養骨芽細胞様細胞の増殖と石灰化に対する効果. 第32回日本レーザー歯学会総会・学術大会 2020.11.28 誌上開催

  9. Ohsugi Y, Katagiri S, Hirota T, Niimi H, Hatasa M, Watanabe K, Shimohira T, Mizutani K, Kitazawa M, Matsuzawa A, Kadokura H, Yokose S, Iwata T, Aoki A. Laser irradiation decreases Sost expression in bone and osteogenic cells. The 106th Annual meeting American Academy of Periodontology 2020.11.06 Virtual

  10. Niimi H, Ohsugi Y, Katagiri S, Watanabe K, Hatasa M, Shimohira T, Tsuchiya Y, Maekawa S, Hirota T, Kadokura H, Yokose S, Iwata T, Aoki A. The effects of Er:YAG laser irradiation on primary osteoblast-like cells. AAP 106th Annual Meeting 2020.11.06 Virtual

  11. Hatasa M, Ohsugi Y, Katagiri S, Hirota T, Yoshida S, Morita K, Niimi H, Shimohira T, Watanabe K, Sasaki N, Maekawa S, Nitta H, Iwata T. Endotoxemia by Porphyromonas gingivalis aggravates inflammation in brown adipose tissue. AAP 106th Annual Meeting 2020.11.06

  12. Shimohira T, Katagiri S, Ohsugi Y, Hirota T, Hatasa M, Mizutani K, Watanabe K, Niimi H, Iwata T, Aoki A. Comprehensive and sequential gene expression analysis during bone healing process following Er:YAG laser ablation. 第63回春季日本歯周病学会 2020.07.13

  13. Shimohira T, Katagiri S, Ohsugi Y, Hirota T, Mizutani K, Watanabe K, Niimi H, Hatasa M, Meinzer W, Iwata T, Aoki A . Comprehensive and Sequential Gene expression analysis of bone healing process following Er:YAG laser ablation. World Federation of Laser Dentistry Dubai Congress 2020 2020.02.05

  14. Ohsugi Y, Katagiri S, Mizutani K, Takagi T, Kakizaki S, Kitanaka Y, Watanabe K, Niimi H, Hatasa M, Shimohira T, Meinzer W, Hirota T, Iwata T, Aoki A. Microarray analysis of comprehensive gene expression in rat calvarial bone after Er:YAG laser ablation. The first asian pacific division of the World Federation for Laser Dentistry 2019.11.10 Beijing

  15. Ohsugi Y, Katagiri S, Mizutani K, Takagi T, Kakizaki S, Kitanaka Y, Watanabe K, Niimi H, Meinzer W, Hirota T, Iwata T, Aoki A. Comprehensive gene expression analysis in rat calvarial bone after ablation with Er:YAG laser and the effects of Er:YAG laser on osteocytes. The 105th Annual meeting American Academy of Periodontology 2019.11.03 Chicago, IL

  16. 坪川正樹, 柿﨑 翔, 大杉勇人, 北中祐太郎, 水谷幸嗣, 角 保徳, 岩田隆紀, 青木 章.. OCTによるプラークの検出および定量. 第62回秋季日本歯周病学会学術大会 2019.10.25 小倉

  17. Ohsugi Y, Aoki A, Mizutani K, Katagiri S, Komaki M, Noda M, Takagi T, Kakizaki S, Kitanaka Y, Lin T, Meinzer W, Izumi Y. Comprehensive Analysis of Gene Expression Related to Healing After Bone Ablation with Er:YAG Laser. 2019.04.04 Dallas, Texus, US

  18. Ohsugi Y, Aoki A, Mizutani K, Katagiri S, Komaki M, Noda M, Takagi T, Kakizaki S, Meinzer W, Izumi Y. Comparison of Er:YAG laser ablation vs. Bur drilling in rat calvarial bone healing. The 16th congress of the World Federation for lasers Dentistry (WFLD) 2018.10.02 Aachen, Germany

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Awards & Honors 【 display / non-display

  • JSP Research Encouragement Award (Ohsugi Y),Japanese Society of Periodontology,2023.05

  • Dr. Eugene M. Seidner Student Scholarship First Prize (Ohsugi Y), ALD,Academy of Laser Dentistry,2019.04