論文・総説 - 岡田　隆平

1. Atsushi Kaida, Yuriko Igarashi, Hitomi Nojima, Mio Nakayama, Ryuhei Okada, Ryosuke Takahashi, Hisataka Kobayashi, Masahiko Miura. Uncovering cell cycle-dependent effects on cell survival in near-infrared photoimmunotherapy. Experimental Cell Research. 2025.05; 448 (2): 114570. ( PubMed, DOI )

2. Shuhei Okuyama, Daiki Fujimura, Aki Furusawa, Hiroshi Fukushima, Ryuhei Okada, Tairo Ogura, Masayuki Nishimura, Peter L Choyke, Hisataka Kobayashi. Urinary IR700 Ligand as an Early Biomarker of Therapeutic Efficacy of Near-Infrared Photoimmunotherapy. ACS Omega. 2025.02; 10 (7): 6983-6991. ( PubMed, DOI )

3. Hiroshi Fukushima, Aki Furusawa, Ryuhei Okada, Yasuhisa Fujii, Peter L Choyke, Hisataka Kobayashi. Antitumor host immunity enhanced by near-infrared photoimmunotherapy. Cancer Sci. 2024.12; ( PubMed, DOI )

4. Ryuhei Okada, Taku Ito, Hiroaki Kawabe, Takeshi Tsutsumi, Takahiro Asakage. Mixed reality-supported near-infrared photoimmunotherapy for oropharyngeal cancer: a case report. Ann Med Surg (Lond). 2024.09; 86 (9): 5551-5556. ( PubMed, DOI )

5. Fuyuki F Inagaki, Makoto Kano, Aki Furusawa, Takuya Kato, Ryuhei Okada, Hiroshi Fukushima, Seiichiro Takao, Shuhei Okuyama, Peter L Choyke, Hisataka Kobayashi. Near-infrared photoimmunotherapy targeting PD-L1: Improved efficacy by preconditioning the tumor microenvironment. Cancer Sci. 2024.07; 115 (7): 2396-2409. ( PubMed, DOI )

6. Yusuke Mizuno, Ryuhei Okada, Susumu Kirimura, Ryoichi Yoshimura, Takahiro Asakage. A Case of Malignant Transformation of Recurrent Respiratory Papillomatosis That Was Effectively Treated with Pembrolizumab Case Rep Oncol. 2024.07; 17 (1): 734-740. ( DOI )

7. Fujikawa T, Ito T, Okada R, Sawada M, Mohri K, Tateishi Y, Takahashi R, Asakage T, Tsutsumi T. Combined genetic polymorphisms of the GSTT1 and NRF2 genes increase susceptibility to cisplatin-induced ototoxicity: A preliminary study. Hearing research. 2024.04; 445 108995. ( PubMed, DOI )

8. Shigeru Kondo, Ryuhei Okada, Yosuke Ariizumi, Takashi Kurita, Hiroshi Shintaku, Takahiro Asakage. A Case of Syphilis Suspected Preoperatively as a Case of Tongue Cancer. Case Rep Otolaryngol. 2023.11; 2023 9469814. ( PubMed, DOI )

9. Naoyuki Sakihama, Ryuhei Okada, Naoto Takahashi, Naoki Fushimi, Tomoki Ooka, Hiroaki Kawabe, Yosuke Ariizumi, Kazuchika Ohno, Yutaka Ueki, Niro Tayama, Takeshi Tsutsumi, Takahiro Asakage. Post-intubation laryngeal injury after COVID-19 treatment causing dyspnea: A report of six cases. Auris Nasus Larynx. 2023.10; 50 (5): 816-820. ( PubMed, DOI )

10. Takumi Kumai, Hirotaka Shinomiya, Hirofumi Shibata, Hideaki Takahashi, Toshihiro Kishikawa, Ryuhei Okada, Shigeharu Fujieda, Masafumi Sakashita. Translational research in head and neck cancer: Molecular and immunological updates. Auris Nasus Larynx. 2023.08; 51 (2): 391-400. ( PubMed, DOI )

11. Ryuhei Okada. [Ⅴ. Future Prospects of Photoimmunotherapy]. Gan To Kagaku Ryoho. 2023.07; 50 (7): 794-798. ( PubMed )

12. Fuyuki F Inagaki, Hiroaki Wakiyama, Aki Furusawa, Ryuhei Okada, Takuya Kato, Daiki Fujimura, Shuhei Okuyama, Hiroshi Fukushima, Seiichiro Takao, Peter L Choyke, Hisataka Kobayashi. Near-infrared photoimmunotherapy (NIR-PIT) of bone metastases. Biomed Pharmacother. 2023.04; 160 114390. ( PubMed, DOI )

13. Takuya Kato, Aki Furusawa, Ryuhei Okada, Fuyuki Inagaki, Hiroaki Wakiyama, Hideyuki Furumoto, Hiroshi Fukushima, Shuhei Okuyama, Peter L Choyke, Hisataka Kobayashi. Near-Infrared Photoimmunotherapy Targeting Podoplanin-Expressing Cancer Cells and Cancer-Associated Fibroblasts. Mol Cancer Ther. 2023.01; 22 (1): 75-88. ( PubMed, DOI )

14. Moriya T, Hashimoto M, Matsushita H, Masuyama S, Yoshida R, Okada R, Furusawa A, Fujimura D, Wakiyama H, Kato T, Choyke PL, Kusumoto Y, Chtanova T, Kobayashi H, Tomura M.. Near-infrared photoimmunotherapy induced tumor cell death enhances tumor dendritic cell migration Cancer Immunology Immunotherapy. 2022.12; 71 (12): 3099-3106. ( PubMed )

15. Wakiyama H, Furusawa A, Okada R, Inagaki F, Kato T, Furumoto H, Fukushima H, Okuyama S, Choyke PL, Kobayashi H.. Opening up new VISTAs: V-domain immunoglobulin suppressor of T cell activation (VISTA) targeted near-infrared photoimmunotherapy (NIR-PIT) for enhancing host immunity against cancers Cancer Immunology Immunotherapy. 2022.12; 71 (12): 2869-2879. ( PubMed )

16. Takuya Kato, Hiroshi Fukushima, Aki Furusawa, Ryuhei Okada, Hiroaki Wakiyama, Hideyuki Furumoto, Shuhei Okuyama, Seiichiro Takao, Peter L Choyke, Hisataka Kobayashi. Selective depletion of polymorphonuclear myeloid derived suppressor cells in tumor beds with near infrared photoimmunotherapy enhances host immune response. Oncoimmunology. 2022.11; 11 (1): 2152248. ( PubMed, DOI )

17. Hiroaki Wakiyama, Takuya Kato, Aki Furusawa, Ryuhei Okada, Fuyuki Inagaki, Hideyuki Furumoto, Hiroshi Fukushima, Shuhei Okuyama, Peter L Choyke, Hisataka Kobayashi. Treg-Dominant Tumor Microenvironment Is Responsible for Hyperprogressive Disease after PD-1 Blockade Therapy. Cancer Immunol Res. 2022.11; 10 (11): 1386-1397. ( PubMed, DOI )

18. Kato T, Okada R, Furusawa A, Wakiyama H, Furumoto H, Fukushima H, Okuyama S, Choyke PL, Kobayashi H.. Comparison of the Effectiveness of IgG Antibody versus F(ab') 2 Antibody Fragment in CTLA4-Targeted Near-Infrared Photoimmunotherapy Molecular Pharmaceutics. 2022.10; 19 (10): 3600-3611. ( PubMed )

19. Fukushima H, Kato T, Furusawa A, Okada R, Wakiyama H, Furumoto H, Okuyama S, Kondo E, Choyke PL, Kobayashi H.. Intercellular adhesion molecule-1-targeted near-infrared photoimmunotherapy of triple-negative breast cancer Cancer Science. 2022.09; 113 (9): 3180-3192. ( PubMed )

20. Fuyuki F Inagaki, Takuya Kato, Aki Furusawa, Ryuhei Okada, Hiroaki Wakiyama, Hideyuki Furumoto, Shuhei Okuyama, Peter L Choyke, Hisataka Kobayashi. Disialoganglioside GD2-Targeted Near-Infrared Photoimmunotherapy (NIR-PIT) in Tumors of Neuroectodermal Origin. Pharmaceutics. 2022.09; 14 (10): 2037. ( PubMed, DOI )