Graduating School 【 display / non-display 】
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Tokyo Medical and Dental University, Faculty of Medicine, 2011.03, Graduated
Graduate School 【 display / non-display 】
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Tokyo Medical and Dental University, Doctor's Course, 2019.03, Completed
Campus Career 【 display / non-display 】
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2015.04-2019.03Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Systemic Organ Regulation, Gastroenterology and Hepatology, Graduate Student
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2019.10Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Hospital Departments, Department of Internal Medicine, Gastroenterology and Hepatology, Project Assistant Professor
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2019.11-2020.03Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Hospital Departments, Department of Internal Medicine, Gastroenterology and Hepatology, Project Assistant Professor
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2020.04-2020.09Tokyo Medical and Dental University, (Old Organization)Medical Hospital, Hospital Departments, Department of Internal Medicine, Gastroenterology and Hepatology, Technical Staff
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2020.10-2022.05Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Systemic Organ Regulation, Gastroenterology and Hepatology, Assistant Professor
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2022.06-NowTokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Systemic Organ Regulation, Gastroenterology and Hepatology, Assistant Professor
Published Papers & Misc 【 display / non-display 】
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Jun Tsuchiya, Masato Miyoshi, Sei Kakinuma, Fukiko Kawai-Kitahata, Akihide Kamiya, Taro Shimizu, Ayako Sato, Keiya Watakabe, Tomohiro Mochida, Kento Inada, Rion Kamimae, Shun Kaneko, Miyako Murakawa, Sayuri Nitta, Mina Nakagawa, Mamoru Watanabe, Yasuhiro Asahina, Ryuichi Okamoto. Hepatitis B Virus-KMT2B Integration Drives Hepatic Oncogenic Processes in a Human Gene-edited Induced Pluripotent Stem Cells-derived Model. Cell Mol Gastroenterol Hepatol. 2024.10; Online ahead of print 101422. ( PubMed, DOI )
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Watakabe K, Miyoshi M, Kakinuma S, Sato A, Tsuchiya J, Shimizu T, Mochida T, Inada K, Kaneko S, Kawai-Kitahata F, Murakawa M, Nitta S, Nakagawa M, Oshima S, Watanabe M, Ma A, Asahina Y, Okamoto R. A20 in hepatic stellate cells suppresses chronic hepatitis by inhibiting DCLK1-JNK pathway-dependent chemokines. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2024.07; 38 (13): e23757. ( PubMed, DOI )
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Murakawa M, Nakagawa M, Nishimura H, Kaneko S, Miyoshi M, Kawai-Kitahata F, Nitta S, Tsuchiya J, Shimizu T, Watakabe K, Mochida T, Inada K, Iizuka Y, Sakai H, Sakurai Y, Sato A, Azuma S, Kawamura T, Maeyashiki C, Kurosaki M, Kusano F, Watanabe H, Kurata H, Karakama Y, Fujiwara T, Nagata Y, Tanaka T, Kakinuma S, Okamoto R, Asahina Y. High serum gamma-glutamyltransferase level after hepatitis C virus elimination is a risk factor for the development of hepatocellular carcinoma. Hepatology research : the official journal of the Japan Society of Hepatology. 2024.07; ( PubMed, DOI )
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Shun Kaneko, Yasuhiro Asahina, Miyako Murakawa, Seishin Azuma, Kento Inada, Tomohiro Mochida, Keiya Watakabe, Taro Shimizu, Jun Tsuchiya, Masato Miyoshi, Fukiko Kawai-Kitahata, Sayuri Nitta, Marie Takahashi, Tomoyuki Fujioka, Mitsuhiro Kishino, Tatsuhiko Anzai, Sei Kakinuma, Mina Nakagawa, Ryuichi Okamoto. Analysis of prognosis and background liver disease in non-advanced hepatocellular carcinoma in two decades. PLoS One. 2024; 19 (3): e0297882. ( PubMed, DOI )
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Shun Kaneko, Yasuhiro Asahina, Miyako Murakawa, Shunsuke Ueyama, Chiaki Maeyashiki, Hideki Watanabe, Akiko Kusano-Kitazume, Ayako Sato, Kozue Uchidate, Takehito Asakawa, Sho Watanabe, Yasuhiro Iizuka, Isamu Shibata, Shinya Oooka, Yuko Karakama, Takashi Fujii, Taro Watabe, Keiichi Akahoshi, Minoru Tanabe, Kento Inada, Tomohiro Mochida, Keiya Watakabe, Taro Shimizu, Jun Tsuchiya, Masato Miyoshi, Fukiko Kitahata-Kawai, Sayuri Nitta, Mina Nakagawa, Sei Kakinuma, Ryuichi Okamoto, . Prognostic Significance of C-Reactive Protein in Unresectable Hepatocellular Carcinoma treated with Atezolizumab and Bevacizumab. Hepatol Res. 2023.12; Online ahead of print. ( PubMed, DOI )
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Kaneko Shun, Asahina Yasuhiro, Nakagawa Mina, Murakawa Miyako, Miyazaki Yasunari, Asakage Takahiro, Fukuda Shohei, Namiki Takeshi, Kano Yoshihito, Nagata Masashi, Tsuchiya Jun, Miyoshi Masato, Kitahata-Kawai Fukiko, Nitta Sayuri, Itsui Yasuhiro, Kakinuma Sei, Okamoto Ryuichi. 免疫チェックポイント阻害薬による治療が実施された進行癌患者における肝障害および予後関連因子(Factors associated with liver injury and prognosis in advanced cancer patients treated with immune checkpoint inhibitors) Hepatology Research. 2023.05; 53 (5): 450-459. ( ichushi )
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Shun Kaneko, Yasuhiro Asahina, Mina Nakagawa, Miyako Murakawa, Yasunari Miyazaki, Takahiro Asakage, Shohei Fukuda, Takeshi Namiki, Yoshito Kano, Masashi Nagata, Jun Tsuchiya, Masato Miyoshi, Fukiko Kitahata-Kawai, Sayuri Nitta, Yasuhiro Itsui, Sei Kakinuma, Ryuichi Okamoto. Factors associated with liver injury and prognosis in advanced cancer patients treated with immune checkpoint inhibitors. Hepatol Res. 2023.01; 53 (5): 450-459. ( PubMed, DOI )
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Nakagawa Mina, Nawa Nobutoshi, Takeichi Eiko, Shimizu Taro, Tsuchiya Jun, Sato Ayako, Miyoshi Masato, Kawai-Kitahata Fukiko, Murakawa Miyako, Nitta Sayuri, Itsui Yasuhiro, Azuma Seishin, Kakinuma Sei, Fujiwara Takeo, Watanabe Mamoru, Tanaka Yujiro, Asahina Yasuhiro. 直接作用型抗ウイルス薬(DAA)によるC型肝炎ウイルス根絶後の患者の生存に関する新規予測バイオマーカーとしてのMac-2結合タンパク糖鎖修飾異性体(Mac-2 binding protein glycosylation isomer as a novel predictive biomarker for patient survival after hepatitis C virus eradication by DAAs) Journal of Gastroenterology. 2020.10; 55 (10): 990-999. ( ichushi )
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Mina Nakagawa, Nobutoshi Nawa, Eiko Takeichi, Taro Shimizu, Jun Tsuchiya, Ayako Sato, Masato Miyoshi, Fukiko Kawai-Kitahata, Miyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Takeo Fujiwara, Mamoru Watanabe, Yujiro Tanaka, Yasuhiro Asahina, . Mac-2 binding protein glycosylation isomer as a novel predictive biomarker for patient survival after hepatitis C virus eradication by DAAs. J. Gastroenterol. 2020.08; 55 (10): 990-999. ( PubMed, DOI )
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Nitta Sayuri, Takahashi Kazuaki, Kawai-Kitahata Fukiko, Tsuchiya Jun, Sato Ayako, Miyoshi Masato, Murakawa Miyako, Itsui Yasuhiro, Nakagawa Mina, Azuma Seishin, Kakinuma Sei, Watanabe Mamoru, Asahina Yasuhiro. 慢性E型肝炎患者におけるウイルス配列および免疫グロブリン抗体価の経時変化(Time course alterations of virus sequences and immunoglobulin titers in a chronic hepatitis E patient) Hepatology Research. 2020.04; 50 (4): 524-531. ( ichushi )
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Sayuri Nitta, Kazuaki Takahashi, Fukiko Kawai-Kitahata, Jun Tsuchiya, Ayako Sato, Masato Miyoshi, Miyako Murakawa, Yasuhiro Istui, Mina Nakagawa, Seishin Azuma, Sei Kakinuma, Mamoru Watanabe, Yasuhiro Asahina. Time course alterations of virus sequences and immunoglobulin titers in a chronic hepatitis E patient Hepatology Research. 2020; 50 (4): 524-531.
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Kawai-Kitahata Fukiko, Asahina Yasuhiro, Kaneko Shun, Tsuchiya Jun, Sato Ayako, Miyoshi Masato, Tsunoda Tomoyuki, Inoue-Shinomiya Emi, Murakawa Miyako, Nitta Sayuri, Itsui Yasuhiro, Nakagawa Mina, Azuma Seishin, Kakinuma Sei, Tanabe Minoru, Sugawara Emiko, Takemoto Akira, Ojima Hidenori, Sakamoto Michiie, Muraoka Masaru, Takano Shinichi, Maekawa Shinya, Enomoto Nobuyuki, Watanabe Mamoru. 肝細胞癌様領域と異時性肝細胞癌が併存する胆管細胞癌の網羅的遺伝子解析(Comprehensive genetic analysis of cholangiolocellular carcinoma with a coexistent hepatocellular carcinoma-like area and metachronous hepatocellular carcinoma) Hepatology Research. 2019.12; 49 (12): 1466-1474. ( ichushi )
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Fukiko Kawai-Kitahata, Yasuhiro Asahina, Shun Kaneko, Jun Tsuchiya, Ayako Sato, Masato Miyoshi, Tomoyuki Tsunoda, Emi Inoue-Shinomiya, Miyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Sei Kakinuma, Minoru Tanabe, Emiko Sugawara, Akira Takemoto, Hidenori Ojima, Michiie Sakamoto, Masaru Muraoka, Shinichi Takano, Shinya Maekawa, Nobuyuki Enomoto, Mamoru Watanabe. Comprehensive genetic analysis of cholangiolocellular carcinoma with a coexistent hepatocellular carcinoma-like area and metachronous hepatocellular carcinoma. Hepatol. Res.. 2019.07; 49 (12): 1466-1474. ( PubMed, DOI )
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Emi Inoue-Shinomiya, Miyako Murakawa, Yasuhiro Asahina, Mina Nakagawa, Jun Tsuchiya, Ayako Sato, Tomoyuki Tsunoda, Masato Miyoshi, Sayuri Nitta, Fukiko Kawai-Kitahata, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Kazumoto Murata, Masashi Mizokami, Mamoru Watanabe. Association of serum interferon-λ3 levels with hepatocarcinogenesis in chronic hepatitis C patients treated with direct-acting antiviral agents. Hepatol. Res.. 2019.05; 49 (5): 500-511. ( PubMed, DOI )
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Inoue-Shinomiya Emi, Murakawa Miyako, Asahina Yasuhiro, Nakagawa Mina, Tsuchiya Jun, Sato Ayako, Tsunoda Tomoyuki, Miyoshi Masato, Nitta Sayuri, Kawai-Kitahata Fukiko, Itsui Yasuhiro, Azuma Seishin, Kakinuma Sei, Murata Kazumoto, Mizokami Masashi, Watanabe Mamoru. 直接作用型抗ウイルス薬を投与されたC型慢性肝炎患者における血清インターフェロン-λ3値と肝細胞癌発症との関連性(Association of serum interferon-λ3 levels with hepatocarcinogenesis in chronic hepatitis C patients treated with direct-acting antiviral agents) Hepatology Research. 2019.05; 49 (5): 500-511. ( ichushi )
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Sayuri Nitta, Yasuhiro Asahina, Takanobu Kato, Jun Tsuchiya, Emi Inoue-Shinomiya, Ayako Sato, Tomoyuki Tsunoda, Masato Miyoshi, Fukiko Kawai-Kitahata, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Sei Kakinuma, Hayato Hikita, Tetsuo Takehara, Mamoru Watanabe. Impact of novel NS5A resistance-associated substitutions of hepatitis C virus detected in treatment-experienced patients. Sci Rep. 2019.04; 9 (1): 5722. ( PubMed, DOI )
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Tomoyuki Tsunoda, Sei Kakinuma, Masato Miyoshi, Akihide Kamiya, Shun Kaneko, Ayako Sato, Jun Tsuchiya, Sayuri Nitta, Fukiko Kawai-Kitahata, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Tsuyoshi Sogo, Haruki Komatsu, Ryutaro Mukouchi, Ayano Inui, Tomoo Fujisawa, Hiromitsu Nakauchi, Yasuhiro Asahina, Mamoru Watanabe. Loss of fibrocystin promotes interleukin-8-dependent proliferation and CTGF production of biliary epithelium. J. Hepatol.. 2019.03; 71 (1): 143-152. ( PubMed, DOI )
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Masato Miyoshi, Sei Kakinuma, Akihide Kamiya, Tomoyuki Tsunoda, Jun Tsuchiya, Ayako Sato, Shun Kaneko, Sayuri Nitta, Fukiko Kawai-Kitahata, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Hiromitsu Nakauchi, Yasuhiro Asahina, Mamoru Watanabe. LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells. Sci Rep. 2019.02; 9 (1): 2072. ( PubMed, DOI )
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Seishin Azuma, Yasuhiro Asahina, Sei Kakinuma, Keiko Azuma, Masato Miyoshi, Emi Inoue, Tomoyuki Tsunoda, Ayako Sato, Shun Kaneko, Hiroko Nagata, Fukiko Kawai-Kitahata, Miyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Makoto Tomita, Mina Nakagawa, Mamoru Watanabe. Diabetic Retinopathy as a Risk Factor Associated with the Development of Hepatocellular Carcinoma in Nonalcoholic Fatty Liver Disease. Dig Dis. 2019; 37 (3): 247-254. ( PubMed, DOI )
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Murakawa Miyako, Asahina Yasuhiro, Nagata Hiroko, Nakagawa Mina, Kakinuma Sei, Nitta Sayuri, Kawai-Kitahata Fukiko, Otani Satoshi, Kaneko Shun, Miyoshi Masato, Tsunoda Tomoyuki, Asano Yu, Sato Ayako, Itsui Yasuhiro, Azuma Seishin, Nouchi Toshihiko, Furumoto Yohei, Asano Tooru, Chuganji Yoshimichi, Tohda Shuji, Watanabe Mamoru. ソホスブビル+リバビリン治療を行ったC型慢性肝炎ジェノタイプ2患者におけるITPA遺伝的変異とリバビリン誘発性貧血(ITPA gene variation and ribavirin-induced anemia in patients with genotype 2 chronic hepatitis C treated with sofosbuvir plus ribavirin) Hepatology Research. 2017.10; 47 (11): 1212-1218. ( ichushi )
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Goto Fumio, Kakinuma Sei, Miyoshi Masato, Tsunoda Tomoyuki, Kaneko Shun, Sato Ayako, Asano Yu, Otani Satoshi, Azuma Seishin, Nagata Hiroko, Kawai-Kitahata Fukiko, Murakawa Miyako, Nitta Sayuri, Itsui Yasuhiro, Nakagawa Mina, Asahina Yasuhiro, Watanabe Mamoru. 骨形成因子4は胎児肝幹/前駆細胞の増殖と最終分化を調整する(Bone morphogenetic protein-4 modulates proliferation and terminal differentiation of fetal hepatic stem/progenitor cells) Hepatology Research. 2017.08; 47 (9): 941-952. ( ichushi )
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Hiroko Nagata, Mina Nakagawa, Yasuhiro Asahina, Ayako Sato, Yu Asano, Tomoyuki Tsunoda, Masato Miyoshi, Shun Kaneko, Satoshi Otani, Fukiko Kawai-Kitahata, Miyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Toshihiko Nouchi, Hideki Sakai, Makoto Tomita, Mamoru Watanabe, . Effect of interferon-based and -free therapy on early occurrence and recurrence of hepatocellular carcinoma in chronic hepatitis C. J. Hepatol. 2017.06; 67 (5): 933-939. ( PubMed, DOI )
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Miyako Murakawa, Yasuhiro Asahina, Hiroko Nagata, Mina Nakagawa, Sei Kakinuma, Sayuri Nitta, Fukiko Kawai-Kitahata, Satoshi Otani, Shun Kaneko, Masato Miyoshi, Tomoyuki Tsunoda, Yu Asano, Ayako Sato, Yasuhiro Itsui, Seishin Azuma, Toshihiko Nouchi, Yohei Furumoto, Tooru Asano, Yoshimichi Chuganji, Shuji Tohda, Mamoru Watanabe. ITPA gene variation and ribavirin-induced anemia in patients with genotype 2 chronic hepatitis C treated with sofosbuvir plus ribavirin. Hepatol. Res. 2017.01; 47 (11): 1212-1218. ( PubMed, DOI )
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Miyako Murakawa, Yasuhiro Asahina, Fukiko Kawai-Kitahata, Mina Nakagawa, Sayuri Nitta, Satoshi Otani, Hiroko Nagata, Shun Kaneko, Yu Asano, Tomoyuki Tsunoda, Masato Miyoshi, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Yasuhito Tanaka, Sayuki Iijima, Kaoru Tsuchiya, Namiki Izumi, Shuji Tohda, Mamoru Watanabe. Hepatic IFNL4 expression is associated with non-response to interferon-based therapy through the regulation of basal interferon-stimulated gene expression in chronic hepatitis C patients. [Epub ahead of print] J. Med. Virol. 2016.12; 89 (7): 1241-1247. ( PubMed, DOI )
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Masato Miyoshi, Sei Kakinuma, Yoko Tanabe, Koji Ishii, Tian-Cheng Li, Takaji Wakita, Yukio Tsuura, Hideki Watanabe, Yasuhiro Asahina, Mamoru Watanabe, Takaaki Ikeda. Chronic Hepatitis E Infection in a Persistently Immunosuppressed Patient Unable to Be Eliminated after Ribavirin Therapy. Intern. Med. 2016.10; 55 (19): 2811-2817. ( PubMed, DOI )
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Miyoshi Masato, Kakinuma Sei, Tanabe Yoko, Ishii Koji, Li Tian-Cheng, Wakita Takaji, Tsuura Yukio, Watanabe Hideki, Asahina Yasuhiro, Watanabe Mamoru, Ikeda Takaaki. 恒常的免疫抑制患者における慢性E型肝炎感染はリバビリン療法後に排除することができない(Chronic Hepatitis E Infection in a Persistently Immunosuppressed Patient Unable to Be Eliminated after Ribavirin Therapy) Internal Medicine. 2016.10; 55 (19): 2811-2817. ( ichushi )
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Fumio Goto, Sei Kakinuma, Masato Miyoshi, Tomoyuki Tsunoda, Shun Kaneko, Ayako Sato, Yu Asano, Satoshi Otani, Seishin Azuma, Hiroko Nagata, Fukiko Kawai-Kitahata, Miyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Mina Nakagawa, Yasuhiro Asahina, Mamoru Watanabe. Bone morphogenetic protein-4 modulates proliferation and terminal differentiation of fetal hepatic stem/progenitor cells. Hepatol. Res. 2016.09; 47 (9): 941-952. ( PubMed, DOI )
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Shun Kaneko, Sei Kakinuma, Yasuhiro Asahina, Akihide Kamiya, Masato Miyoshi, Tomoyuki Tsunoda, Sayuri Nitta, Yu Asano, Hiroko Nagata, Satoshi Otani, Fukiko Kawai-Kitahata, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Hiromitsu Nakauchi, Hironori Nishitsuji, Saneyuki Ujino, Kunitada Shimotohno, Masashi Iwamoto, Koichi Watashi, Takaji Wakita, Mamoru Watanabe. Human induced pluripotent stem cell-derived hepatic cell lines as a new model for host interaction with hepatitis B virus. Sci Rep. 2016.07; 6 29358. ( PubMed, DOI )
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Hiroko Nagata, Mina Nakagawa, Yuki Nishimura-Sakurai, Yu Asano, Tomoyuki Tsunoda, Masato Miyoshi, Shun Kaneko, Fumio Goto, Satoshi Otani, Fukiko Kawai-Kitahata, Miyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Naoko Tojo, Shuji Tohda, Yasuhiro Asahina, Mamoru Watanabe, . Serial measurement of Wisteria floribunda agglutinin positive Mac-2-binding protein is useful for predicting liver fibrosis and the development of hepatocellular carcinoma in chronic hepatitis C patients treated with IFN-based and IFN-free therapy.[Epub ahead of print] Hepatol Int. 2016.07; 10 (6): 956-964. ( PubMed, DOI )
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Satoshi Otani, Sei Kakinuma, Akihide Kamiya, Fumio Goto, Shun Kaneko, Masato Miyoshi, Tomoyuki Tsunoda, Yu Asano, Fukiko Kawai-Kitahata, Sayuri Nitta, Toru Nakata, Ryuichi Okamoto, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Yasuhiro Asahina, Tomoyuki Yamaguchi, Naohiko Koshikawa, Motoharu Seiki, Hiromitsu Nakauchi, Mamoru Watanabe. Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells. Biochem. Biophys. Res. Commun. 2016.01; 469 (4): 1062-1068. ( PubMed, DOI )
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Nagawa F, Kishishita N, Shimizu K, Hirose S, Miyoshi M, Nezu J, Nishimura T, Nishizumi H, Takahashi Y, Hashimoto S, Takeuchi M, Miyajima A, Takemori T, Otsuka AJ, Sakano H. Antigen-receptor genes of the agnathan lamprey are assembled by a process involving copy choice. Nature immunology. 2007.02; 8 (2): 206-13. ( PubMed, DOI )
Conference Activities & Talks 【 display / non-display 】
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Mina Nakagawa, Miyako Murakawa, Masato Miyoshi, Shun Kaneko, Tsuchiya Jun, Taro Shimizu, Keiya Watakabe, Sei Kakinuma, Ryuichi Okamoto and Yasuhiro Asahina. High GGT levels is a risk factor for HCC development having potential to reflect mitochondrial dysfunction after HCV eradication. AASLD2024 2024.11.15
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Mina Nakagawa, Miyako Murakawa, Masato Miyoshi, Shun Kaneko, Fukiko Kawai-Kitahata, Sayuri Nitta, Sei Kakinuma, Ryuichi Okamoto and Yasuhiro Asahina. SVR後の肝癌、生存とメタボ因子に関する解析. APASL 2024 Kyoto 2024.03.28
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Mina Nakagawa, Miyako Murakawa, Masato Miyoshi, Shun Kaneko, Fukiko Kawai-Kitahata, Sayuri Nitta, Sei Kakinuma, Yasuhiro Asahina, Ryuichi Okamoto. Factors associated with HCC development and patients’ survival in patients with an SVR. The 3rd JSH International Liver Conference 2023.09.07
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柿沼晴,三好正人,朝比奈靖浩. ヒトiPS細胞由来肝構成細胞を用いた細胞間相互作用の解析. 第58回日本肝臓学会総会 2022.06.02
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Mina Nakagawa, Masato Miyoshi, Fukiko Kawai-Kitahata, Miyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Yasuhiro Asahina. Factors associated with HCC development and patients’ survival in patients with an SVR. JSH International Liver Conference 2021 2021.10.03
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Fukiko Kawai-Kitahata, Yasuhiro Asahina , Sei Kakinuma, Miyako Murakawa, Sayuri Nitta, Masato Miyoshi, Ayako Sato, Jun Tsuchiya, Taro Shimizu, Eiko Takeichi, Mina Nakagawa, Yasuhiro Itsui, Seishin Azuma, Shinji Tanaka , Minoru Tanabe, Shinya Maekawa, Nobuyuki Enomoto and Mamoru Watanabe. Comprehensive analysis of cancer-related genes and aav/hepatitis b virus integration into genome on development of hepatocellular carcinoma in patients with prior hepatitis b virus infection. EASL The Digital International Liver Congress 2020 2020.08.28 Web開催
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Miyako Murakawa, Yasuhiro Asahina, Emi Inoue, Mina Nakagawa, Jun Tuchiya, Ayako Sato, Masato Miyoshi, Tomoyuki Tsunoda, Fukiko Kitahata-Kawai, Sayuri Nitta, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Mamoru Watanabe. The association of serum IFN-lambda 3 levels with liver fibrosis and hepatocarcinogenesis in chronic hepatitis C patients treated with direct-acting antiviral agents . EASL, The International Liver Congress 2019 2019.04.13 Vienna (Austria)
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MIna Nakagawa, Yasuhiro Asahina, Jun Tsuchiya, Ayako Sato, Tomoyuki Tsunoda, Msato Miyosh, Emi Inoue, Fukiko Kawai-Kitahata, MIyako Murakawa, Sayuri Nitta, Yasuhiro Itsui, Seishin Azuma, Sei Kakinuma, Makoto Tomita, Mamoru Watanabe. Impact of HCV clearance on HCC development and patient survival: Propensity score-matched analysis of an ongoing database of 2173 CHC patients. EASL, The International Liver Congress 2019 2019.04.13 Messe Wien Congress and Exhibition Center(Vienna (Austria))
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Nitta S, Kato T, Tuchiya J, Sato A, Tsunoda T, Miyoshi M, Inoue- Shinomiya E, Kawai-Kitahata F, Murakawa M, Itsui Y, Nakagawa M, Azuma S, Kakinuma S, Asahina Y. The Characteristic and the Anti-HCV Reagents Susceptibility Analysis of NS5A Resistance-Associated Substitutions (RAS) Detected after Daa Treatment Failure Patients. AASLD, The Liver Meeting 2018 2018.11.10 San Francisco (USA)
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Nitta S, Kato T, Tuchiya J, Shinomiya-Inoue E, Sato A, Tsunoda T, Miyoshi M, Kitahata-Kawai F, Murakawa M, Istui Y, Azuma S, Nakagawa M, Kakinuma S, Asahina Y. The in vitro analysis of NS5A resistance-associated substitutions (RAS) observed in DAA treatment failure patients. 25th International Symposium on Hepatitis C Virus and Related Viruses 2018.10.09 Dublin(Ireland)
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Kitahata-kawai F, Asahina Y, KakinumaS, Murakawa M, Nitta S, Nagata H, Kaneko S, Inoue E, Miyoshi M, Tsunoda T, Sato A, Nakagawa M, Itsui Y, Azuma S, Tanaka S, Tanabe M, Maekawa S, Enomoto N and Watanabe M. Difference of gene mutational profile among viral- and non-viral HCC with or without prior HBV infection: Results of comprehensive deep sequencing analyses of cancer genes and HBV/A AV integration. EASL, The International Liver Congress 2018 2018.04.14 Paris(France)
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Shun Kaneko, Sei Kakinuma, Yasuhiro Asahina, Akihide Kamiya, Masato Miyoshi, Tomoyuki Tsunoda, Emi Inoue-Shinomiya, Sayuri Nitta, Ayako Sato, Yu Asano, Hiroko Nagata, Fukiko Kawai-Kitahata, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Mamoru Watanabe. A novel culture model for coinfection of hepatitis B and hepatitis C viruses using human induced pluripotent stem cell–derived hepatic cells for analyses of changes in host-innate immune responses . AASLD The Liver Meeting 2017 2017.10.22 Washington DC
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Miyako Murakawa, Yasuhiro Asahina, Mina Nakagawa, Sayuri Nitta, Fukiko Kawai-Kitahata, Hiroko Nagata, Syun Kaneko, Yu Asano, Masato Miyoshi, Tomoyuki Tsunoda, Emi Inoue-Shinomiya, Ayako Sato, Yasuhiro Itsui, Sei Kakinuma, Seishin Azuma, Mamoru Watanabe. On-treatment higher levels of alpha-fetoprotein and M2BPGi are associated with development of hepatocellular carcinoma during nucleos(t)ide analog therapy in patients with HBV chronic infection. AASLD, The Liver Meeting 2017 2017.10.21 Washington DC
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Shun Kaneko, Sei Kakinuma, Yasuhiro Asahina, Akihide Kamiya,Masato Miyoshi, Tomoyuki Tsunoda, Sayuri Nitta, Ayako Sato, Yu Asano, Hiroko Nagata, Satoshi Otani, Fukiko Kawai-Kitahata, Miyako Murakawa, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Mamoru Watanabe. Genetically modified human induced pluripotent stem cell-derived hepatic progenitor-like cell lines as a model for interaction between hepatitis B virus and host cells. AASLD The Liver meeting 2016 2016.11.11 Boston(USA)
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Kaneko S, Kakinuma S, Asahina Y, Kamiya A, Nitta S, Tsunoda T, Miyoshi M, Asano Y, Nagata H , Goto F., Otani S, Kitahata F, Murakawa M, Itsui Y, Nakagawa M, Azuma S, Watanabe M. A new model for studying interaction between hepatitis B virus and host cells derived from human induced pluripotent stem cells. EASL The International Liver Congress 2016 2016.04.14 Barcelona(Spain)
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Kaneko S, Kakinuma S, Asahina Y, Kamiya A, Nitta S, Tsunoda T, Miyoshi M, Asano Y, Nagata H, Goto F, Otani S, Kitahata F, Murakawa M , Itsui Y, Nakagawa M, Azuma S, Watanabe M. A Model for Interaction between HBV and Host Cells Derived from Human Induced Pluripotent Stem Cells. The 25th Asian Pacific Association for the Study of the Liver 2016.02.22 International Convention Center Pamir, Tokyo(JAPAN)
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Kawai-Kitahata F, Asahina Y, Tanaka S, Kakinuma S, Murakawa M, Nitta S, Otani S, Goto F, Nagata H, Kaneko S, Asano Y, Miyoshi M, Tsunoda T, Azuma S, Itsui Y, Nakagawa M, Tanabe M, Maekawa S, Enomoto N, Watanabe M. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma. The 25th Asian Pacific Association for the Study of the Liver 2016.02.22 International Convention Center Pamir, Tokyo(JAPAN)
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Shun Kaneko, Sei Kakinuma, Yasuhiro Asahina, Akihide Kamiya, Sayuri Nitta, Tomoyuki Tsunoda, Masato Miyoshi, Hiroko Nagata, Fumio Goto, Satoshi Otani, Miyako Murakawa, Fukiko Kawai-Kitahata, Yasuhiro Itsui, Mina Nakagawa, Seishin Azuma, Mamoru Watanabe. Human induced pluripotent stem cell-derived hepatic progenitor-like cells and hepatocyte-like cells as a model for interaction between hepatitis B virus and host cells. AASLD The Liver Meeting 2015 2015.11.16 San Francisco, CA
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